Search

Background: Ventricular arrhythmias (VA) can be life-threatening complications of myocardial infarction (MI). In coronary artery disease (CAD), the main substrates of arrhythmia are fibrous areas of the ventricular myocardium formed after a previous MI. This study aimed to evaluate the hypothesis that left ventricular mechanical dispersion (LVMD) can identify subjects at high risk for developing VA among post-MI patients with left ventricular ejection fractions (LVEFs) >40%. Methods and Results: The study included 100 CAD patients (mean age of 62.7±9.61 years) with a history of acute Q-wave MI no earlier than two months. According to the Lown grading system, all patients (59% men and 41% women) were divided into two groups based on the presence of premature ventricular contractions (PVCs). Group 1 consisted of 58 patients with PVCs, and Group 2 included 42 patients without PVCs. All patients underwent general clinical examination, biochemical blood tests, and functional methods (daily ECG monitoring, standard transthoracic two-dimensional echocardiography [TTE] with ECG synchronization, 2D-STE with the assessment of global longitudinal strain [GLS] and left ventricular mechanical dispersion [LVMD]). In the general patient group, analysis of the two-dimensional TTE parameters indicated relative preservation of the LV structural and functional parameters, except for a slight decrease in the systolic function with a mildly abnormal LVEF of 45.9±11.5%. A comparative analysis of clinical and demographic indicators in groups with and without PVCs demonstrated relative homogeneity and comparability regarding average age, the duration of CAD and hypertension, lipid metabolism indicators, and structural and functional parameters of the left ventricle and left atrium (P>0.05). We studied the deformation properties of the left ventricle in the longitudinal direction in three apical views. The integral average GLS value was -12.98±3.34% in the group with PVCs and -13.49±3.43% in the group without PVCs (P=0.458). The LVMD was significantly higher in patients with PVCs than those without PVCs: 34.07±9.3 ms versus 9.8±5.54 ms (P=0.000). The analysis of the 2D-STE parameters showed the absence of statistically significant differences in the LVGLS (F=0.8585, P=0.4655) between the subgroups, taking into account the Lown grading system for PVCs, but significant differences in the LVMD were noted. The minimal mean LVMD value (9.3±5.57 ms) was revealed in the group with PVC Grade 0. LVMD increased with the increasing the PVC grade, reaching maximum values in the subgroup with PVC Grades IV- V: 15±8.37 ms in the subgroup with PVC Grades I-II, 34.0±6.30 ms in the subgroup with PVC Grade III, 49.8±12.8 ms in the subgroup with PVC Grades IV-V (F=129.6136, P=0.0000). Conclusion: Left ventricular mechanical dispersion, determined by 2-D STE, is an important prognostic marker related to the development of ventricular arrhythmia in post-MI patients with intermediate LVEF.

IntroductionA National Immunization Technical Advisory Group (NITAG) provides independent guidance to Ministries of Health (MoH) and policymakers, enabling them to make informed decisions on national immunization policies and practices. As of 2022, 50 of the 53 countries in the World Health Organization (WHO) European Region (the Region) had established a NITAG, with 58% of all NITAGs and 66% of those in middle-income countries (MICs) in the Region meeting all six WHO process indicators of NITAG functionality. However, many newly established NITAGs in MICs in the Region experience challenges in terms of their functioning, structure, and outputs.MethodsTo address these challenges and achieve the goal of evidence-informed decision making on immunizations, the WHO Regional Office for Europe and the Robert Koch Institute (RKI) implemented a project to strengthen the functioning of MIC NITAGs of the Region through comprehensive evaluations of nine NITAGs and development and implementation of improvement plans.ResultsAll evaluated NITAGs are formally established and complete the most important aspects of NITAG functioning. The main challenge for all NITAGs is the lack of a well-staffed Secretariat to establish annual workplans and develop NITAG recommendations following a standardized process.DiscussionThe evaluation identified NITAGs' strengths and challenges. Some challenges have been addressed through improvement plan implementation. WHO and RKI will continue to evaluate NITAGs and support development and implementation of improvement plans. WHO and NITAG partners will continue to provide training on the standardized recommendation-making process and advocate increased MoH support to NITAGs, including dedicated Secretariat staff.

This paper reviews epidemiological data on primary hyperparathyroidism (PHPT). PHPT is an endocrine disease caused by a tumor or hyperplastic changes in the parathyroid glands (PTG); it leads to disturbances in calcium-phosphorus homeostasis and can cause organ dysfunction. The results of epidemiological studies in various countries indicate an "epidemic" of PHPT at the end of the 20th century. Currently, PHPT ranks as the third endocrine problem in the world. Its prevalence is about 0.86-1% in people under 50 and 2% in people over 50. It was found that PHPT occurs more often in people aged 40-60 years, with an increase in the frequency of its detection after 25 years of age, especially in women after menopause. The review emphasizes the importance of PHPT, which represents a severe medical and social problem. Regular screening and the introduction of modern diagnostic methods play a vital role in the timely detection and management of PHPT, which is of great importance for improving patients' quality of life and preventing severe complications. When compiling the literature review, we used the following databases: PubMed, Embase, Medline, ScienceDirect, Cochrane Library, eLibrary, and CyberLeninka. The literature search was carried out using the following keywords: "epidemiology of primary hyperparathyroidism", "prevalence", "incidence", "normocalcemic hyperparathyroidism", "parathyroid gland", and "parathyroid hormone". The search identified more than 1070 scientific papers, from which 48 studies were selected. These studies cover the epidemiological aspects (incidence and prevalence) of PHPT conducted in various countries. The selection was done without considering each study's specific period and volume of observations. The selection process focused on studies using automated blood calcium analyzers to evaluate the impact of regular screening on the effectiveness of detecting PHPT. Works presenting both global and regional data were also included in the analysis. Studies that did not meet the established selection criteria were excluded.

Nematodes are the most widespread multicellular organisms found in soil ecosystems. They engage in complex and diverse relationships with plants and other living organisms. Additionally, the composition of nematode communities varies across different climatic conditions. This study was conducted in the Zarafshan Valley of Uzbekistan, where the species and ecological diversity of nematodes have not been thoroughly explored. Our research identified 87 nematode species belonging to seven orders across various biotopes associated with tomato plants in three regions of the Zarafshan Valley. Notably, the majority of these species were found in the rhizosphere soil. For the first time in this region, we classified nematodes into ecological groups based on their trophic characteristics, revealing that the bacterivores group is the most dominant. We calculated ecological indicators for nematodes in different biotopes using the Simpson index (Dˊ), Shannon index (Hˊ), Menhinck index, Margalef index, and Berger-Parker index. The diversity of nematode fauna across these biotopes was analyzed in relation to soil organic matter content, humidity, and pH levels. Our findings further demonstrate that variations in the species and ecological composition of nematodes among biotopes are influenced by multiple factors, particularly their trophic characteristics.

Adverse environmental conditions, including drought stress, pose a significant threat to plant survival and agricultural productivity, necessitating innovative and efficient approaches to enhance their resilience. MicroRNAs (miRNAs) are recognized as key elements in regulating plant adaptation to drought stress, with a notable ability to modulate various physiological and molecular mechanisms. This review provides an in-depth analysis of the role of miRNAs in drought response mechanisms, including abscisic acid (ABA) signaling, reactive oxygen species (ROS) detoxification, and the optimization of root system architecture. Additionally, it examines the effectiveness of bioinformatics tools, such as those employed in in silico analyses, for studying miRNA-mRNA interactions, as well as the potential for their integration with experimental methods. Advanced methods such as microarray analysis, high-throughput sequencing (HTS), and RACE-PCR are discussed for their contributions to miRNA target identification and validation. Moreover, new data and perspectives are presented on the role of miRNAs in plant responses to abiotic stresses, particularly drought adaptation. This review aims to deepen the understanding of genetic regulatory mechanisms in plants and to establish a robust scientific foundation for the development of drought-tolerant crop varieties.

Over the past decade, the topic of climate change has become an integral part of our everyday life. Significant anthropogenic impact on the environment contributes to the acceleration of this process and leads to catastrophic consequences in some regions. This directs the views of scientists in many industries to the development and implementation of environmentally friendly technologies, waste-free production and the use of non-traditional approaches to the ecology of production, including agriculture. One of the areas that has recently attracted the attention of scientists from many countries around the world is the use of microalgae, among which Chlorella vulgaris is becoming increasingly popular, having a wide range of applications. The paper presents the results of the effect of a suspension culture of living cells of the microalga Chlorella vulgaris, as well as a suspension preparation of Chlorella vulgaris grown on digestate, on changes in the chemical composition of sand and on the sowing qualities of winter wheat seeds of the Shestopalovka variety. A high positive correlation was established between the length of roots and coleoptiles of winter wheat seedlings of the Shestopalovka variety (r = 0.86) in the variant with an aqueous concentration of the suspension “Chlorella with Digestat”.

This study aimed to investigate the possibility of extracting protein from chicken feathers. We conducted our research in a controlled laboratory environment, where we carefully washed feathers collected from white broiler chickens. The feathers were ground and hydrolyzed using a 1:10 ratio of 0.2 eq/L of standard sodium hydroxide (NaOH) solution and 28.5 % sodium hydrosulfite (NaHSO3) solutions. The hydrolyzed solution was further processed in a 90 °C water bath for 6 h using a rotor stirrer. After this, the solution was neutralized with 99 % acetic acid (CH3COOH) and filtered. The filtrate was dialyzed with distilled water in a cellophane membrane bag for 24 h. Following dialysis, we obtained two samples of the dried and ground protein. The first sample was subjected to physicochemical analysis, while the second sample was treated with 5 % H2O2 before analysis. Our analysis, conducted using the Kjeldahl and liquid chromatography methods, revealed that 68–78 % of proteins were synthesized. The study of free amino acids found that the highest indicator, which belongs to 38–40 % of cysteine, asparagine, glutamine, and tryptophan in the protein, failed because of alkaline hydrolysis. However, samples 1 and 2 of the protein containing 17 free amino acids were comparable, further validating our findings.

Monilinia fructigena Pers is a specialized fungus known for its impact on pome crops, particularly during the fruiting phase. This pathogen is responsible for causing significant damage through fruit rot, affecting fruit quality and economic outcomes for growers. The primary objective of this research was to comprehensively investigate M. fructigena Pers, its distribution, and its effects on various fruit crops. Additionally, the study aimed to identify other fungal species associated with fruit rot and assess varietal resistance among different fruit tree varieties. Between 2021 and 2023, isolates of fungi belonging to the Monilinia genus were collected from fruits, inflorescences, shoots, and fruit formations of apple trees affected by moniliosis. Identification was conducted using polymerase chain reaction with species-specific primers and sequencing of the ITS 1-5.8S rRNA-ITS 2 locus of ribosomal DNA. The prevalence and impact of M. fructigena Pers and other identified fungi were analyzed. M. fructigena Pers was found to be the dominant fungus, with a frequency of occurrence ranging from 91.6 to 100%. This fungus was responsible for damage to inflorescences, shoots (monilial burn), and fruits (fruit rot). Other fungi, such as Fusarium proliferatum and Alternaria alternata, were also identified. Quarantine species M. fructicola was not found in the research orchards. In addition, varietal resistance experiments revealed differing susceptibility levels among apple tree varieties, with the Maksat variety being more susceptible than Voskhod. In conclusion, M. fructigena posed a significant threat to fruit crops, particularly pome varieties, in the studied regions. The research shed light on its prevalence, distribution, and impact. In addition, the identification of other fungal species associated with fruit rot provided valuable insights into disease management. The variable varietal resistance underscores the challenges of breeding for fruit rot resistance and highlights the importance of continued research in this area for more effective disease control strategies.

Introduction. In the last decade, a high-throughput 16S ribosomal RNA (rRNA) sequencing allowed to markedly extend insights into female reproductive tract microbiome. However, evidence about its role on in vitro fertilization (IVF) outcomes remains scarce and controversial.Aim: to analyze literature data for assessing an impact of the vaginal, uterine, and ovarian microbiome on IVF outcomes.Materials and Methods. The review was carried out based on publications from available in PubMed/MEDLINE, EBSCO, ResearchGate, Google Academy and еLibrary databases released over the last 20 years. For this, there was search for keywords and their combinations in Russian- and English-written publications: «vaginal microbiome», «cervical microbiome», «uterine microbiome», «ovarian microbiome», «microbiome of ovarian follicles», «IVF», «miscarriage», «early pregnancy loss», «implantation failure», «ovarian failure», «inflammasome». Only full-text original articles and reviews published in peer-reviewed journals were included in the review. Exclusion criteria were as follows: studies containing less than 10 observations per group, abstracts of conferences, studies on the male reproductive tract microbiome. Duplicate publicationswere excluded. The publications were selected independently by two co-authors, and in case of discrepancy two other co-authors were involved.Results. Vaginal, uterine, and ovarian microbiomes were characterized by providing relevant classifications and the features related to implantation failures and pregnancy loss after IVF. It was found that a decline in total Lactobacillus level and elevated proportion of L. jensenii, G. vaginalis, and Proteobacteria in the vaginal microbiome were predictors of implantation failure. In addition, IVF failure was also associated with the presence of Atopobium, Bifidobacterium, Chryseobacterium, Gardnerella, Streptococcus, Haemophilus, Staphylococcus, Brevundimonas, and Ralstonia in the uterine cavity as well as Bifidobacterium, Gardnerella, and Klebsiella in the endometrial tissue. On the other hand, Lactobacillus dominance in the uterine microbiome has a favorable effect. The colonization of the follicle by any microorganisms as well as the presence of follicular fluid anaerobic bacteria-derived metabolite trimethylamine-N-oxide (TMAO) associated with bacterial vaginosis additionally alters IVF outcomes. Moreover, the role of infectious cues in lowered ovarian reserve has also been established. Activation of the NLRP3 (NLR Family Pyrin Domain Containing 3) inflammasome by microbe-derived ligands stimulates production of pro-inflammatory cytokines and contributes to reduced follicle number. Blocking NLRP3 in mouse experiments can delay depletion of the follicle pool and result in elevated fertility.Conclusion. Favorable IVF outcomes are associated with Lactobacillus predominance in the vaginal and endometrial microbiome as well as lack of follicular fluid microorganisms. TMAO detected in the follicular fluid as well as activated NLRP3 inflammasome serve as negative predictors of IVF outcomes.

Link for citation: Mazlova E.A., Blinovskaya Ya.Yu., Sokolova L.I., Tursunova G.Sh. Organochlorine pesticides pollution of the bottom sediments of Nakhodka bay and Partizanskaya river. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 9, рр. 25-35. In Rus. Relevance. The new data on the organochlorine pesticides pollution of the bottom sediments of Nakhodka bay and Partizanskaya river were obtained in 2020–2021. The objective of the article is to report the organochlorine pesticides pollution level of the bottom sediments and to define the possible sources of organochlorine pesticides in the marine environment. Techniques: sample collection of bottom sediments, Gas Chromatography Mass Spectrometry analysis of samples, Gas-liquid Chromatography method with electronic capture detector, statistical processing, assessment of the organochlorine pesticides contamination of sediments. Results. The new data were obtained on the organochlorine pesticides concentrations in Nakhodka bay in 2020–2021. The previous data on the studied area are described. The concentration of HCH pesticides (α- , β- and γ-HCH), DDT and its metabolites was analyzed. It was found that the concentration of α- , β- HCCH and DDT in bottom sediments increased in 2021.To determine the quality of bottom sediments, the average annual values of organochlorine pesticides concentrations in the bottom sediments gathered during the field works were compared with the quality guidelines. There are no approved quality guidelines for maximum permissible concentrations of pollutants in bottom sediments in the Russian Federation. For this reason, we used the quality guidelines applied in foreign countries («Dutch sheets» (Neue Niederlandische Liste. NNL) and Canadian quality standards for marine and estuarine bottom sediments (Canadian Sediment Quality Guidelines, CSQGs). Possible sources of organochlorine pesticides in the marine environment were analyzed. The results of this work showed that despite the ban on the use of these substances, these pesticides are included in the multiple compounds used in different industries and continue to enter and accumulate in the marine environment.

The incidence of osteoarticular tuberculosis in 15 regions of the Siberian and Far Eastern Federal Districts from 2018 to 2020 was assessed. The incidence of osteoarticular tuberculosis and co-infection of osteoarticular tuberculosis with HIV and osteoarticular tuberculosis with hepatitis B/C was analyzed. Variants of osteoarticular tuberculosis with respiratory tuberculosis, variants of tuberculosis sites in the bone articular system and the most typical neurological disorders in those patients were presented.

In this paper, we consider covariant functors F : Comp [right arrow] Comp acting in category of shape-preserving compact sets [2], infinite compact sets, and shape equivalence [6]. Also we study action of compact functors and shape properties of the compact space X consisting of connected components [??]X of the compact X as well as shape identity ShX = ShY of infinite compacts X and Y for the space P(X) of probability measures and its subspaces., CONTENTS 1. Introduction 21 2. Topologies on Subspaces of Spaces of Probabilistic Measures 23 3. Main Part 25 References 31 1. Introduction If X is a compactum, then P(X) denotes [...]

In the present work the application of the spectral method with Chebyshev polynomials of the second kind is considered for solving a boundary value problem of an ordinary differential equation with a small parameter at the highest derivative. Numerical and graphical results illustrate the effectiveness of the applied method for various values of polynomials.

Adverse environmental conditions, including drought stress, pose a significant threat to plant survival and agricultural productivity, necessitating innovative and efficient approaches to enhance their resilience. MicroRNAs (miRNAs) are recognized as key elements in regulating plant adaptation to drought stress, with a notable ability to modulate various physiological and molecular mechanisms. This review provides an in-depth analysis of the role of miRNAs in drought response mechanisms, including abscisic acid (ABA) signaling, reactive oxygen species (ROS) detoxification, and the optimization of root system architecture. Additionally, it examines the effectiveness of bioinformatics tools, such as those employed in in silico analyses, for studying miRNA-mRNA interactions, as well as the potential for their integration with experimental methods. Advanced methods such as microarray analysis, high-throughput sequencing (HTS), and RACE-PCR are discussed for their contributions to miRNA target identification and validation. Moreover, new data and perspectives are presented on the role of miRNAs in plant responses to abiotic stresses, particularly drought adaptation. This review aims to deepen the understanding of genetic regulatory mechanisms in plants and to establish a robust scientific foundation for the development of drought-tolerant crop varieties. [ABSTRACT FROM AUTHOR]

The global water crisis, which intensifies each year, underscores the urgent need for accurate assessment and sustainable management of freshwater resources. Lakes, as significant components of surface water systems, are particularly vulnerable to human activities and climate change due to their slow renewal rates. Western Kazakhstan, a region affected by economic development and intensive mining activities, faces acute water scarcity. A reliable water supply is crucial to meeting the requirements of industrial operations and the needs of the region's population. Understanding the dynamics of lake systems and implementing effective conservation and restoration strategies are essential to addressing this challenge. This study, employing cartographic and remote sensing techniques, identified 323 lakes in Western Kazakhstan, covering a total area of 1944 km2. Comparative analysis with historical data from the 1960s and 1970s revealed a 23% decrease in the number of lakes exceeding 1 km2. The most significant decline was observed in the Atyrau and Mangystau Regions, where the number of such lakes diminished by a factor of three. These findings highlight the pressing need for an integrated, interdisciplinary approach to water resource management in Western Kazakhstan. [ABSTRACT FROM AUTHOR]

This article presents an analysis of the calculation of the distribution of river flow in the irrigation system by depth of flow. These studies aim to understand the dynamics of river flows and the impact of irrigation, with researchers dedicating years to this endeavor . In the clarifiers, the larger and medium fractions of sediments should be retained in such quantities that they cannot be transported by the downstream channels. In this case, it is not allowed to re-cool the water in the clarifier, as this will cause the channels in the system to be washed and reduce the fine particles that will increase the productivity of the fields It is known that many scientific studies have been conducted on the depth of river flows. In this case, we will analyze the distribution of river sediments along the depth of the current, using the proposed formulas for calculation. Furthermore, research has demonstrated that the distribution of river flows by depth follows a linear pattern with increasing flow rate or a higher percentage of smaller fractions in suspended particle composition. This distribution characteristic has been observed in various related studies. The practical and scientific findings of these studies are exemplified through research conducted at the “Ekin-Tekin Pumping Station” in the Andijan region, serving as a significant case study in this field. We chose the “Ekin-Tekin pumping station„ located in the Andijan region, as the object of research, and calculated the distribution of turbidity of the river at this pumping station depending on the depth of the flow.

In this article, polymerization processes are carried out under various physicochemical conditions. The reaction medium can be a solution of the polymer in a monomer or solvent with a viscosity from 10-3 to 102 -103 Pa, a suspension of solid polymer particles in a hydrocarbon diluent or water with a polymer concentration from 10 to 60%, aqueous dispersions, gas systems solid. Thermodynamic conditions and kinetic characteristics can also vary within wide limits: temperature from 70 to 300 °C, and contact time from tens of seconds to several hours. Polymerization processes typically involve significant heat release (60-100 kJ/mol). In a number of cases, directly or indirectly, temperature and hydrodynamic (shear) conditions affect the molecular weight distribution or dispersed composition of polymer particles and, thus, determine the physical and mechanical properties of the polymer. Naturally, the implementation of the necessary temperature, concentration, and hydrodynamic conditions depends on the design and type of reactor.

The comparison of cerebral circulation impairment in humans and horses provides important insights into the dynamics of blood flow in the brain across different species, connecting veterinary and human medicine. This analysis brings together findings from various studies to highlight the similarities in anatomy and physiology between humans and horses, which can improve our understanding of cerebrovascular health. Research emphasizes the importance of maintaining stable cerebral blood flow to prevent damage from lack of oxygen, which is essential for the brain’s metabolism in both humans and horses. Studies on the factors affecting overall blood flow in the body reveal strong connections between cardiovascular health and blood flow to the brain, showing how baroreflex sensitivity and blood pressure play a role in maintaining brain function. Understanding the reactivity of blood vessels in the brain is associated with neurological disorders, emphasizing the need for non-invasive evaluation techniques that can be used for both humans and horses. Research on the coupling of nerve and blood vessel activity further explains how blood flow is regulated during brain activity, highlighting potential weaknesses under unhealthy conditions. While the role of exercise in promoting cerebrovascular health is recognized, there are still gaps in our knowledge of its effects on the brain, especially in horses. Advanced imaging techniques like MRI are presented as essential tools for assessing the health of small blood vessels and blood flow in the brain, offering potential applications in the early detection and treatment of cerebrovascular diseases. By comparing the dynamics of blood flow in the brain in humans and horses, this review not only increases our understanding but also suggests a more integrated approach to diagnosis and treatment, improving practices in both fields. These insights emphasize the common principles and specific differences in cerebrovascular health in different species, and support the need for collaborative research in veterinary and human medicine.

Calculation of foundations using elastic models simplifies the calculation of loads and impacts on foundations. However, in some cases they can significantly distort the real deformations, foundation efforts and in some cases cause their damage. In practice, designing and calculating foundations using these models, there are cases of excessively high concentrations of bending moments and shear forces, which requires a high percentage of reinforcement in these nodes. Sometimes, for example, with distributed loads, with the real presence of such efforts, calculations performed on models with a bedding coefficient show, on the contrary, their absence. The type of the adopted model and the rigidity of the foundation structures have a significant impact on the calculated deflection of the beam. The value of the adopted values of the model parameters also has a great impact on the calculation results. Calculation models in the area of contact with the soil base, the reactive pressure of the foundation P (x) linearly depends on the coefficient of local soil compression C1 and the shear resistance of the soil C2.

Today, many countries are extraction the underground resources (non-ferrous and rare metals) by having a leading processing plants. In Uzbekistan, metals such as gold, silver, copper, uranium, rhenium, and tungsten are mined from underground resources and produced as finished products. A significant part of the costs of the extraction of underground resources is spent on the processes of crushing and grinding crushing minerals. Hard alloys used in the process of crushing and grinding ores are produced based on metals such as tungsten and cobalt. This article presents scientific-practical research on the properties of powders that form the basis of tungsten carbide-cobalt-based hard alloys used in crushing underground resources. During the research, the chemical composition of tungsten and cobalt carbide powders chosen as raw materials, the location of the powders in the raw materials, the granulometric sizes of the powders, and their morphology were studied. In all conducted studies, tungsten carbide powders produced at the JSC “Almalyk MMC” were used as a raw material to prepare samples of tungsten carbide-cobalt-based hard alloys and also as a binder. Cobalt powder produced in this enterprise was selected. All studies were carried out on a scanning electron microscope, JSM-IT200 (JEOL, Japan), at the Uzbekistan-Japan Youth Innovation Center.

An examination of various approaches, methods, and technologies recommended as optimal for safeguarding atmospheric air against dust pollution has led to the identification of the distinct advantages associated with vortex inertial dust collectors utilizing swirling currents. These collectors, referred to as Cyclone Separation Fans (CSF), have been determined to serve as primary and auxiliary equipment in dust removal systems within the production of building materials and other industries. Traditionally employed circuit designs for dust collection systems were also subject to analysis, revealing two prevalent types: open and partially closed air circulation systems. In the latter, a portion of the cleaned airflow is reintroduced into the system, representing a key feature of the design. This assessment underscores the significance of vortex inertial dust collectors, specifically CSFs, as instrumental components in dust removal systems across various industrial sectors. Their effectiveness in mitigating dust pollution, coupled with their versatility as both primary and supplementary equipment, positions them as recommended technologies for atmospheric air protection in the production of building materials and other related industries. The recognition of open and partially closed air circulation systems in traditional dust collection circuit designs further contributes to refining and optimizing dust removal processes for enhanced environmental protection.

The theory of river flow transport is the major cause in the development of the irrigation sector and largely determines the stability of the irrigation scheme. Crop water requirements vary due to climate and crop growth stages. For this reason, the flow of sediments changes during the irrigation season. In this article, in order to evaluate the carrying capacity of the canals, researches in natural field conditions were carried out in the Amu-zang canal belonging to the “Amu-Surkhan Irrigation Systems” basin administration. Flow transportability in natural channels was calculated for particles with d=0.05 mm by S.Kh.Abalyans, A.Zamarin, A.M.Arifzhanov and Engelund and Hansen methods. A histogram of the dependence of flow capacity, channel depth and average speed on the Amuzang channel was obtained, according to which it was determined that the flow capacity is 1.5-1.8 kg/m3 in the range of 0.6-0.8 m/s.

Article mentions the use of a new technology for cleaning irrigation systems from muddy sediments. This technology was modeled and tested using Ansys Mechanical Finite Element Analysis (FEA) Software for Structural Engineering. Analytical analyzes were carried out to maintain the design parameters of irrigation system coatings. As a result of the analysis, a deformable tooth device using a wedge with a unit of k (N/m) is applied to the coating with an impact force F (N) at an angle of α =100-300, so that it is compressed in the range of Δl =5-15 (mm) without damaging the coating of the irrigation system. determined.

Chemical (oxidation, oxygen demand, Al, CNS, As, Co, Ni, Zn, Cr, Cu, Pb, Mn, Na, K, H2S, CO2, C (organic matter), total mineralization, B, Br, J, SiO2, total hardness, NO3-, Cl-, SO42-, HCO3-, CO32-, Fe (total), Mg2+, Ca2+, dry matter, pH, acidity, alkalinity, XPK) and physical (clarity, sedimentation, color level, odor) properties of water samples collected for analysis from 7 water springs (Spring No. 42, Spring No. 43, Spring No. 44, Spring No. 45, Spring No. 46, Spring No. 47, Spring No. 48) and it was investigated (during 2019-2022). The results of laboratory analyzes were evaluated and according to the results, it was proved that the spring water serves as a drinking water, but does not meet the requirements as a healing mineral water.

See the retraction notice E3S Web of Conferences 538, 00001 (2024), https://doi.org/10.1051/e3sconf/202453800001

This paper discusses methods of obtaining fuel briquettes from hydrocarbon-containing waste of oil refineries as a binder, as well as conducts a comparative analysis of the operational characteristics of the obtained products and previously known fuel briquettes. To improve the operational properties of oil sludge briquettes, research is conducted and an optimal composition of the fuel briquette based on licorice root waste in combination with a binder mixture based on oil and fat residues is proposed. The paper provides a technology for obtaining a binder mixture based on oil and fat residues. Six types of alternative road bitumen samples based on the developed composition have been obtained, and research has been conducted on the following indicators: water absorption of the fuel briquette, total moisture in the fuel briquette, degree of ash content, and the amount of total sulfur in the fuel briquette. The article also presents a recommended technological scheme for the production of fuel briquettes using licorice root waste as a binder mixture.

The study presents biological characteristics of the major apple pests in Uzbekistan. For evaluating the key insects, field observation has been conducted. The in-situ results have identified six major apple pests in three selected research areas of the province. Thus, in this study, the biological behavior and potential harm of the determined pests on apple trees are provided. This field-based investigation helps to establish an integrated method to fight against those harmful pests and their devastating influence.