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Whilst there is growing concern within archaeology about the wider impact of archaeological research in general, only limited attention has so far been paid to the impact fieldwork has on local communities. Here, using examples from fieldwork with an agro‐pastoral Mursi community in Ethiopia's Lower Omo Valley, we present a case in which local oral traditions are modified in response to archaeological discoveries. This illustrates a particular example of the impact of fieldwork during and after its completion; and the enduring traces of contact upon fieldwork participants. We argue that in employing an attitude of impact practice within fieldwork that foregrounds the Socratic notion of dialogue, the resulting focus highlights the value and significance of archaeology to local communities.

The first transition-metal complex-based two-photon absorbing luminescence lifetime probes for cellular DNA are presented. This allows cell imaging of DNA free from endogenous fluorophores and potentially facilitates deep tissue imaging. In this initial study, ruthenium(II) luminophores are used as phosphorescent lifetime imaging microscopy (PLIM) probes for nuclear DNA in both live and fixed cells. The DNA-bound probes display characteristic emission lifetimes of more than 160 ns, while shorter-lived cytoplasmic emission is also observed. These timescales are orders of magnitude longer than conventional FLIM, leading to previously unattainable levels of sensitivity, and autofluorescence-free imaging.

The first transition-metal complex-based two-photon absorbing luminescence lifetime probes for cellular DNA are presented. This allows cell imaging of DNA free from endogenous fluorophores and potentially facilitates deep tissue imaging. In this initial study, ruthenium(II) luminophores are used as phosphorescent lifetime imaging microscopy (PLIM) probes for nuclear DNA in both live and fixed cells. The DNA-bound probes display characteristic emission lifetimes of more than 160 ns, while shorter-lived cytoplasmic emission is also observed. These timescales are orders of magnitude longer than conventional FLIM, leading to previously unattainable levels of sensitivity, and autofluorescence-free imaging.

Pastoral and agro-pastoral areas in eastern Africa and elsewhere on the continent have long been regarded as peripheries, especially in economic terms, but also in terms of social and cultural accomplishments. Although biased perceptions of the 'unproductive' uses of pastoralism have become outdated, government policies still do little to formally recognise or integrate pastoral lands as critical parts of rural livelihood systems and economic development models. Instead, many states give preference to large-scale agricultural investments in pastoral areas, resulting in the loss or fragmentation of rangelands, induced sedentarisation of pastoralists, and a radical reduction in livestock numbers. The Lands of the Future Research Network supports the view that alienation of pastoralists from productive lands often is unwarranted, unproductive, and unadvisable. In such cases it would be better for the overall economy and society to leave things as they are, or, if 'development' comes in, to discuss the development potential of pastoralism. In other cases of integrated economies, combining old and new forms ('mixed agriculture' on a societal scale) might offer advantages to all groups of participants as well as the national economy. Drawing on research from Ethiopia, Kenya, Sudan, and Tanzania our paper looks at the significance of pastoralism as a productive economy and the positive bearing it has on the environment, wildlife conservation, and on the health and well-being of pastoral communities. The paper also reflects on what is at stake when one form of land use is replaced by another and when customary rules and practices regarding land access, land use, and traditional law are not fully recognised by policy makers. Using historical examples (e.g. from Afar) and current development trends (e.g. Ethiopia's river basin development in the Omo Valley), the paper shows how the impacts of such development need not be negative (e.g. forced displacement, resettlement, conflict). The authors urge development planners and governments to integrate the expertise of agro-pastoralists into development models and to establish strong relationships between investors, NGOs, GOs, policy makers, researchers, local communities, and other stakeholders in order to find equitable and long-term solutions for changing land uses.

Objective. After previously reporting the presence of disease by cytology findings after treatment for cervical intra-epithelial neoplasia (CIN) in 64.6% of HIV-infected women and in 13.0% of HIV-negative women, we aimed to determine the severity of cytological disease after treatment in HIV-infected women.Methods. We studied HIV-infected (N=571) women treated at the Colposcopy Clinic at Chris Hani Baragwanath Hospital, Gauteng, between April 2003 and December 2006. We compared the initial histology results with Pap smears .6 months later, and evaluated factors associated with reduction in the grade of disease.Results. Mean age was 36.68 (SD+7.33) years; mean parity was 2 (SD+1.46); mean CD4+ count was 242.70 cells/ƒÊl (SD+187.56); 262 (45.80%) were receiving antiretroviral treatment. Persistent disease was detected on the repeat Pap smear in 199 (65.03%); of these, 223 (72.88%) were of a lesser grade than in the original histology results. Of the 152 with histologically confirmed CIN3, 67 (44.08%) had improved to a lesser grade, and 54 (44.63%) had normal cytology results. Among the latter two subject groups (n=141) who had CIN2 histologically, 91 (64.53%) had improved, 29 (20.57%) remained unchanged, and 20 (14.88%) had CIN3; 13 (4.25%) patients with CIN1 returned for follow-up; 11 (84.62%) of these had normal Pap smears and 2 (15.38%) had CIN3.Conclusion. Recurrences were of a lesser degree than initial histology results. This reduction in the grade of disease was related to CD4+ count, complete excision and parity. Antiretroviral therapy use did not improve outcome, perhaps owing to low initial CD4 counts.

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