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4. Burden of disease due to transportation noise in the Nordic countries

Author

Aasvang, Gunn Marit, primary, Stockfelt, Leo, additional, Sørensen, Mette, additional, Turunen, Anu, additional, Roswall, Nina, additional, Yli-Tuomi, Tarja, additional, Ögren, Mikael, additional, Kollanus, Virpi, additional, Lanki, Timo, additional, Selander, Jenny, additional, Vincens, Natalia, additional, Pyko, Andrei, additional, Pershagen, Göran, additional, Sulo, Gerhard, additional, and Kocbach Bølling, Anette, additional

Published
2023
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5. Socioeconomic inequalities in burden of disease due to traffic noise in the Nordic countries

Author

Bolling, Anette Kocbach, primary, Thacher, Jesse Daniel, additional, Klitkou, Søren Toksvig, additional, Baravelli, Carl Michael, additional, Andersson, Eva, additional, Stockfelt, Leo, additional, Vincens, Natalia, additional, Sørensen, Mette, additional, Turunen, Anu, additional, Yli-Tuomi, Tarja, additional, Ögren, Mikael, additional, Kollanus, Virpi, additional, Lanki, Timo, additional, Selander, Jenny, additional, Sulo, Gerhard, additional, and Aasvang, Gunn Marit, additional

Published
2023
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7. Long-term Exposure to Particulate Matter Constituents and the Incidence of Coronary Events in 11 European Cohorts

Author

Wolf, Kathrin, Stafoggia, Massimo, Cesaroni, Giulia, Andersen, Zorana Jovanovic, Beelen, Rob, Galassi, Claudia, Hennig, Frauke, Migliore, Enrica, Penell, Johanna, Ricceri, Fulvio, Sørensen, Mette, Turunen, Anu W., Hampel, Regina, Hoffmann, Barbara, Kälsch, Hagen, Laatikainen, Tiina, Pershagen, Göran, Raaschou-Nielsen, Ole, Sacerdote, Carlotta, Vineis, Paolo, Badaloni, Chiara, Cyrys, Josef, de Hoogh, Kees, Eriksen, Kirsten T., Jedynsk, Aleksandra, Keuken, Menno, Kooter, Ingeborg, Lanki, Timo, Ranzi, Andrea, Sugiri, Dorothea, Tsai, Ming-Yi, Wang, Meng, Hoek, Gerard, Brunekreef, Bert, Peters, Annette, and Forastiere, Francesco

Published
2015

8. Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Östenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Published
2014
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11. Long term exposure to ambient air pollution and incidence of acute coronary events : prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project

Author

Cesaroni, Giulia, Forastiere, Francesco, Stafoggia, Massimo, Andersen, Zorana J, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, de Faire, Ulf, Erbel, Raimund, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Hampel, Regina, Heier, Margit, Hennig, Frauke, Hilding, Agneta, Hoffmann, Barbara, Houthuijs, Danny, Jöckel, Karl-Heinz, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K E, Migliore, Enrica, Ostenson, Caes-Göran, Overvad, Kim, Pedersen, Nancy L, Juha, Pekkanen J, Penell, Johanna, Pershagen, Göran, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Salomaa, Veikko, Swart, Wim, Turunen, Anu W, Vineis, Paolo, Weinmayr, Gudrun, Wolf, Kathrin, de Hoogh, Kees, Hoek, Gerard, Brunekreef, Bert, and Peters, Annette

Published
2014

13. Socioeconomic inequalities in burden of disease due to traffic noise in the Nordic countries.

Author

Kocbach Bølling, Anette, Thacher, Jesse Daniel, Toksvig Klitkou, Søren, Baravelli, Carl Michael, Andersson, Eva M., Stockfelt, Leo, Vincens, Natalia, Sørensen, Mette, Turunen, Anu, Yli-Tuomi, Tarja, Ögren, Mikael, Kollanus, Virpi, Lanki, Timo, Selander, Jenny, Sulo, Gerhard, and Aasvang, Gunn Marit

Subjects
TRAFFIC noise, SOCIOECONOMICS, REGRESSION analysis, NOISE pollution
Abstract

Environmental noise is the second largest environmental risk factor in disease burden estimates for Europe. While socioeconomic inequalities in noise exposure have been reported, the impact of socioeconomic status (SES) on the disease burden attributable to noise exposure has to our knowledge not been reported previously. The aim of this study is to assess the impact of SES on traffic noise exposure and the associated disease burden in selected Nordic populations. We have employed nationwide data on road traffic noise exposure and SES from the Danish Nationwide Model, and will also include the Norwegian Nationwide Model and cohorts from all the Nordic countries in future analyses. The impact of household income, education and type of housing on traffic noise exposure was assessed using linear regression analyses. The most consistent finding was that, compared to medium and low income, high income was associated with lower noise exposure. Based on stratified exposure distributions according to income (low, medium and high) burden of disease estimates were calculated in terms of Years Lived with Disability (YLD) for high degree of noise annoyance. The YLD for high noise annoyance was up to 20% lower in the high compared to the lower income populations. [ABSTRACT FROM AUTHOR]

Published
2023
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16. Air Pollution and Nonmalignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project

Author

Dimakopoulou, Konstantina, Samoli, Evangelia, Beelen, Rob, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei, Hoek, Gerard, Raaschou-Nielsen, Ole, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Jousilahti, Pekka, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nafstad, Per, Schwarze, Per E., Penell, Johanna, Fratiglioni, Laura, Andersson, Niklas, Pedersen, Nancy, Korek, Michal, De Faire, Ulf, Eriksen, Kirsten Thorup, Tjønneland, Anne, Becker, Thomas, Wang, Meng, Bueno-de-Mesquita, Bas, Tsai, Ming-Yi, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Marcon, Alessandro, Kramer, Ursula, Kuhlbusch, Thomas A.J., Vossoughi, Mohammad, Key, Timothy, de Hoogh, Kees, Hampel, Regina, Peters, Annette, Heinrich, Joachim, Weinmayr, Gudrun, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Jacquemin, Bénédicte, Stempfelet, Morgane, Vilier, Alice, Ricceri, Fulvio, Sacerdote, Carlotta, Pedeli, Xanthi, Katsoulis, Michalis, Trichopoulou, Antonia, Brunekreef, Bert, and Katsouyanni, Klea

Published
2014
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18. Long-term exposure to ambient fine particulate matter originating from traffic and residential wood combustion and the prevalence of depression

Author

Allaouat, Sara, primary, Yli-Tuomi, Tarja, additional, Tiittanen, Pekka, additional, Turunen, Anu W, additional, Siponen, Taina, additional, Kukkonen, Jaakko, additional, Kangas, Leena, additional, Kauhaniemi, Mari, additional, Aarnio, Mia, additional, Ngandu, Tiia, additional, and Lanki, Timo, additional

Published
2021
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19. Tuulivoimaloiden infraääni ja terveys

Author

Maijala, Panu, Turunen, Anu, Kurki, Ilmari, and Sainio, Markku

Subjects
selvitys- ja tutkimustoiminta, tutkimus, tuulivoimalat, tutkimustoiminta, terveys, infraääni
Published
2020

25. Air pollution from road traffic and systemic inflammation in adults: a cross-sectional analysis in the European ESCAPE project

Author

Lanki, Timo, Hampel, Regina, Tiittanen, Pekka, Andrich, Siike, Beeien, Rob, Brunekreef, Bert, Dratva, Julia, De Faire, Ulf, Fuks, Kateryna B., Hoffmann, Barbara, Imboden, Medea, Jousilahti, Pekka, Koenig, Wolfgang, Mahabadi, Amir A., Kunzli, Nino, Pedersen, Nancy L., Penell, Johanna, Pershagen, Goran, Probst-Hensch, Nicole M., Schaffner, Emmanuel, Schindler, Christian, Sugiri, Dorothea, Swart, Wim J.R., Tsai, Ming-Yi, Turunen, Anu W., Weinmayr, Gudrun, Wolf, Kathrin, Yli-Tuomi, Tarja, and Peters, Annette

Subjects
Streets, Inflammation, Roads, Air pollution, Environmental issues, Health
Abstract

BACKGROUND: Exposure to particulate matter air pollution (PM) has been associated with cardiovascular diseases. OBJECTIVES: In this study we evaluated whether annual exposure to ambient air pollution is associated with systemic inflammation, which is hypothesized to be an intermediate step to cardiovascular disease. METHODS: Six cohorts of adults from Central and Northern Europe were used in this crosssectional study as part of the larger ESCAPE project (European Study of Cohorts for Air Pollution Effects). Data on levels of blood markers for systemic inflammation--high-sensitivity C-reactive protein (CRP) and fibrinogen--were available for 22,561 and 17,428 persons, respectively. Land use regression models were used to estimate cohort participants' long-term exposure to various size fractions of PM, soot, and nitrogen oxides (N[O.sub.x]). In addition, traffic intensity on the closest street and traffic load within 100 m from home were used as indicators of traffic air pollution exposure. RESULTS: Particulate air pollution was not associated with systemic inflammation. However, cohort participants living on a busy (> 10,000 vehicles/day) road had elevated CRP values (10.2%; 95% CI: 2.4, 18.8%, compared with persons living on a quiet residential street with < 1,000 vehicles/day). Annual N[O.sub.x] concentration was also positively associated with levels of CRP (3.2%; 95% CI: 0.3, 6.1 per 20 µg/[m.sup.3]), but the effect estimate was more sensitive to model adjustments. For fibrinogen, no consistent associations were observed. CONCLUSIONS: Living close to busy traffic was associated with increased CRP concentrations, a known risk factor for cardiovascular diseases. However, it remains unclear which specific air pollutants are responsible for the association., Introduction Exposure to ambient particulate matter pollution (PM) affects both respiratory and cardiovascular health, and is a major contributor to the global burden of disease (Lim et al. 2012). One [...]

Published
2015
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26. Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results from the ESCAPE and TRANSPHORM projects

Author

Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W., Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W., Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Goran, Pedersen, Nancy L., Ostenson, Claes-Goran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sorensen, Mette, Tjonneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L., Meliefste, Kees, Kraemer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Kuenzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Francoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M., Kukkonen, Jaakko, Sokhi, Ranjeet S., Brunekreef, Bert, Katsouyanni, Klea, Hoek, Gerard, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, and IRAS RATIA-SIB

Subjects
Male, Air pollution, Total population, Joint analysis, medicine.disease_cause, NO2, DISEASE, Cohort Studies, HARVARD 6 CITIES, USE REGRESSION-MODELS, 11. Sustainability, Medicine, Adult Aged Cardiovascular Diseases Cohort Studies Environmental Exposure Europe Female Humans Male Middle Aged Particulate Matter Proportional Hazards Models, lcsh:Environmental sciences, General Environmental Science, lcsh:GE1-350, Hazard ratio, Particulate matter air pollution, cardiovascular mortality, epidemiology, Middle Aged, Particulates, 3. Good health, Europe, Pooled analysis, Cardiovascular Diseases, Constituents, Female, EXTENDED FOLLOW-UP, MOUSE LUNG, Adult, Cardiovascular mortality, TIME-SERIES, ESCAPE, CHEMICAL-COMPOSITION, Environmental health, Humans, PARTICLES, Aged, Proportional Hazards Models, Proportional hazards model, business.industry, Long-term exposure, Environmental engineering, Environmental Exposure, AIR-POLLUTION, TRANSPHORM, 13. Climate action, business, Particulate matter
Abstract

Background: Associations between long-term exposure to ambient particulate matter (PM) and cardiovascular (CVD) mortality have been widely recognized. However, health effects of long-term exposure to constituents of PM on total CVD mortality have been explored in a single study only. Aims: The aim of this study was to examine the association of PM composition with cardiovascular mortality. Methods: We used data from 19 European ongoing cohorts within the framework of the ESCAPE (European Study of Cohorts for Air Pollution Effects) and TRANSPHORM (Transport related Air Pollution and Health impacts — Integrated Methodologies for Assessing Particulate Matter) projects. Residential annual average exposure to elemental constituents within particle matter smaller than 2.5 and 10 μm (PM2.5 and PM10) was estimated using Land Use Regression models. Eight elements representing major sources were selected a priori (copper, iron, potassium, nickel, sulfur, silicon, vanadium and zinc). Cohort-specific analyses were conducted using Cox proportional hazards models with a standardized protocol. Random-effects meta-analysis was used to calculate combined effect estimates. Results: The total population consisted of 322,291 participants, with 9545 CVD deaths. We found no statistically significant associations between any of the elemental constituents in PM2.5 or PM10 and CVD mortality in the pooled analysis. Most of the hazard ratios (HRs) were close to unity, e.g. for PM10 Fe the combined HR was 0.96 (0.84–1.09). Elevated combined HRs were found for PM2.5 Si (1.17, 95% CI: 0.93–1.47), and S in PM2.5 (1.08, 95% CI: 0.95–1.22) and PM10 (1.09, 95% CI: 0.90–1.32). Conclusion: In a joint analysis of 19 European cohorts, we found no statistically significant association between long-term exposure to 8 elemental constituents of particles and total cardiovascular mortality. Keywords: Long-term exposure, Particulate matter, Constituents, Cardiovascular mortality, ESCAPE, TRANSPHORM

Published
2014
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30. Itämeren silakka ravintona – Hyöty-haitta -analyysi

Author

Tuomisto, Jouni T., Niittynen, Marjo, Turunen, Anu, Ung-Lanki, Sari, Kiviranta, Hannu, Harjunpää, Hannu, Vuorinen, Pekka J., Rokka, Mervi, Ritvanen, Tiina, and Hallikainen, Anja

Subjects
Itämeren silakka, dioksiinit, saanti, DALY, rasvahapot, dioksiinin kaltaiset PCB-yhdisteet, D-vitamiini, hyöty-haitta-analyysi
Abstract

Tämän tutkimuksen tarkoitus oli selvittää, onko silakansyönnistä enemmän terveyshyötyä kuin -haittaa Suomessa ja millainen tilanne on eri ikäryhmissä. Aiemmat hyöty-riskiarviot ovat osoittaneet, että kalansyönti on yleensä terveellisempää kuin sen syömättä jättäminen. Tämä johtuu erityisesti kalan terveellisistä omega-3-rasvahapoista. Kuitenkin iso osa hyödyistä tulee aikuisille, joilla on suurentunut sydäntautiriski, ja osa mahdollisista haitoista tulee lapsille hammasvaurioiden ja muiden kehityshäiriöiden riskinä. Eviran toimeksiantona, yhteistyössä THL:n kanssa on vuoden 2014 aikana tehty hyöty-haitta-analyysi, jossa on tarkasteltu nimenomaan eri ikäryhmiä erikseen nykyisen kalankäytön mukaan. Tulokset perustuvat Taloustutkimuksen tekemän kyselyn aineistoon vuodelta 2013, jonka pohjalta on tehty varsinainen terveysvaikutusten tarkastelu. Tulokset ilmaistiin käyttäen haittapainotettuja elinvuosia (Disability Adjusted Life Year DALY) eli yksi DALY vastaa yhtä menetettyä tervettä elinvuotta. Hyödyllisistä ravintoaineista raportissa tarkasteltiin omega-3-rasvahappoja, eikosapentaeenihappoa (EPA) ja dokosaheksaeenihappoa (DHA) sekä D-vitamiinia. Silakassa esiintyvistä terveydelle haitallisista ympäristömyrkyistä tarkasteltiin dioksiineihin luettavia yhdisteitä, joihin kuuluvat polyklooratut dibentso-p-dioksiinit ja polyklooratut furaanit sekä dioksiininkaltaiset polyklooratut bifenyylit (PCB:t). Tulosten mukaan silakansyönti aiheuttaa Suomessa noin 11 (95 % luottamusväli LV 0 – 54) DALY kehityshäiriöistä (hammasvaurio) johtuvaa haittapainotettua elinvuotta (DALY), jotka kaikki kohdistuvat lapsiin äidin välityksellä raskausajan ja imetyksen kautta. Lisäksi silakansyönti aiheuttaa noin 12 (95 % LV 1.7 – 56) DALY dioksiinien aiheuttaman syöpäriskin kautta koko väestössä. Yli 50-vuotiailla naisilla ja varsinkin miehillä silakansyönnin terveyshyödyt ovat selkeästi suuremmat kuin terveyshaitat. Suurimmat terveyshyödyt saadaan sydäntautia ja sydänkuolleisuutta vähentävästä vaikutuksesta, noin -688 (95 % LV -2126 – -41) DALY/vuosi. Tulosten mukaan silakan syönti on vähentynyt väestössä niin paljon, että nykyiset suomalaiset kalan yleiset syöntisuositukset ovat riittävät suojaamaan väestöä dioksiinien ja dioksiinien kaltaisten yhdisteiden aiheuttamilta terveyshaitoilta. Hyöty-haitta-analyysissä tulisi kuitenkin tulevaisuudessa arvioida myös muiden rasvaisten kalojen keräämien ympäristömyrkkyjen kumulatiivisia terveysvaikutuksia ja yleisten syöntisuositusten riittävyyttä. Syftet med denna undersökning var att utreda om konsumtion av strömming från Östersjön ger mer hälsofördelar än hälsoskador i Finland och hurdant läget i olika ålderskategorier är. Tidigare nytta/riskvärderingar har visat att det i allmänhet är hälsosammare att äta fisk än att låta bli att göra det. Det beror särskilt på de hälsosamma omega-3-fettsyrorna i fisken. En stor del av fördelarna tillkommer ändå vuxna personer med förhöjd risk för hjärtsjukdomar och en stor del av skadorna tillkommer barn i form av risk för skador på tänderna och andra utvecklingsstörningar. På uppdrag från Evira och i samarbete med THL har under året 2014 gjorts en nytta/riskanalys, där man uttryckligen granskat olika ålderskategorier skilt för sig i ljuset av den nuvarande konsumtionen av strömming. Resultaten bygger på ett enkätmaterial som Taloustutkimus inhämtat år 2013. Utgående från detta material har sedan den egentliga granskningen av hälsoeffekterna gjorts. Resultaten angavs i form av funktionsjusterade levnadsår (Disability Adjusted Life Year DALY). För de nyttiga näringsämnenas del granskades i rapporten omega-3-fettsyrorna eikosapentaensyra (EPA) och dokosahexaensyra (DHA) och vitamin D. Av de hälsovådliga miljögifterna som förekommer i strömming granskades dioxiner, polyklorerade dibenzo-p-dioxinerna och plyklorerade dibenzofuranerna jämte dioxinliknande polyklorerade bifenylerna (PCB). Resultaten visar att konsumtion av strömming i Finland orsakar cirka 11 (95 % förtroende intervall , FI 0-54) funktionsjusterade levnadsår (DALY) som beror på utvecklingsstörningar (tandskada) och som alla via modern drabbar barn under graviditeten och amningen. Konsumtion av strömming medför också cirka 12 (95 %, FI 1,7-56) DALY via den cancerrisk som dioxinerna orsakar i hela befolkningen. Hos över 50 åriga kvinnor och framförallt män är fördelarna av att äta strömming klart större än hälsoskadorna. De största hälsofördelarna kommer av att risken för hjärtsjukdomar och dödligheten i hjärtsjukdomar minskar, cirka -688 (95 %, FI -2126 -41) DALY/år. Enligt resultaten konsumtion av strömming I Finland har sjunkit till en så låg nivå , att de nuvarande allmänna rekommenderade intagen av fisk konsumtion är tillräckliga för att skydda befolkningen mot hälsoskador av dioxiner eller dioxinlika föreningar. I risk-nytta-analys i framtiden bör ändå utvärderas totala hälsoeffekter av olika miljögifter i andra feta fiskarter ock kolla lämpligheten av rekommendationer av fisk konsumtion. The objective of this study was to determine whether the benefits of eating Baltic Sea herring exceed the risks in Finland, and what the situation is in different age groups. Previous risk-benefit analyses have shown that eating fish is in general healthier than not eating fish. This is particularly due to the healthy omega 3 fatty acids of fish. However, the benefits are largely enjoyed by adults with an elevated risk of heart disease, while children suffer the majority of the risks in the form of dental problems and other developmental disorders. In the riskbenefit analysis carried out to the order of Evira in collaboration with THL during 2014, different age groups were specifically considered separately in the light of current fish consumption. The results are based on the survey of the consumption of Baltic herring conducted by Taloustutkimus in 2013, which was used as the basis for the actual analysis of health effects. The results were expressed as Disability Adjusted Life Years (DALY). Omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as well as vitamin D were analysed in the report as beneficial nutrients. As far as environmental toxins harmful to health are concerned, Baltic herring were analysed for compounds classified as dioxins, which include polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans, as well dioxin-like biphenyls (PCB). According to the results, in Finland eating herring causes ca. 11 (95% confidence interval, CI 0-54) Disability Adjusted Life Years (DALYs) resulting from developmental disorders (dental damage); these affect children via the mother during pregnancy and breastfeeding. In addition, eating herring causes a ca. 12 (95%, CI 1,7-56) DALY cancer risk due to dioxins in the entire population. The health benefits of eating herring clearly exceed risks to health for women and particularly men after the age of 50 years. The greatest health benefits result from the reduction in heart disease and heart-related fatality, ca. –688 (95%, CI -2126 -41) DALY/year. The results show that the consumption of Baltic herring has decreased in Finland to a low level and that the current common dietary advices on fish consumption are adequate to protect the population against the adverse health effects of dioxins and dioxin-like compounds. However, in risk benefit analysis in future it is important to estimate the total health effects of different environmental pollutants and of other fatty fish, and the sufficiency of dietary advices on fish consumption.

Published
2015

31. Long-term exposure to ambient air pollution and incidence of cerebrovascular events: Results from 11 European cohorts within the ESCAPE project

Author

Stafoggia, Massimo, Cesaroni, Giulia, Peters, Annette, Andersen, Zorana J., Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, Cyrys, Josef, de Faire, Ulf, de Hoogh, Kees, Eriksen, Kirsten T., Fratiglioni, Laura, Galassi, Claudia, Gigante, Bruna, Havulinna, Aki S., Hennig, Frauke, Hilding, Agneta, Hoek, Gerard, Hoffmann, Barbara, Houthuijs, Danny, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K., Meisinger, Christa, Migliore, Enrica, Overvad, Kim, Ostenson, Claes-Goran, Pedersen, Nancy L., Pekkanen, Juha, Penell, Johanna, Pershagen, Goran, Pundt, Noreen, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Swart, Wim J. R., Turunen, Anu W., Vineis, Paolo, Weimar, Christian, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Forastiere, Francesco, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, and IRAS RATIA-SIB

Subjects
Male, Health, Toxicology and Mutagenesis, Air pollution, Medizin, 010501 environmental sciences, medicine.disease_cause, NO2, 01 natural sciences, Cohort Studies, 0302 clinical medicine, Risk Factors, USE REGRESSION-MODELS, PARTICULATE MATTER, AREAS, Medicine, 030212 general & internal medicine, ACUTE ISCHEMIC-STROKE, Acute ischemic stroke, Aged, 80 and over, RISK, Air Pollutants, Ambient air pollution, Incidence, Incidence (epidemiology), Middle Aged, Europe, Stroke, Cardiovascular Diseases, Noise, Transportation, PM2.5 ABSORBENCY, Regression Analysis, Female, Nitrogen Oxides, Adult, education, 03 medical and health sciences, Environmental health, Humans, ddc:610, Particle Size, METAANALYSIS, Aged, 0105 earth and related environmental sciences, Extramural, business.industry, Research, MORTALITY, Public Health, Environmental and Occupational Health, Environmental Exposure, PMCOARSE, 13. Climate action, business
Abstract

Background: Few studies have investigated effects of air pollution on the incidence of cerebrovascular events. Objectives: We assessed the association between long-term exposure to multiple air pollutants and the incidence of stroke in European cohorts. Methods: Data from 11 cohorts were collected, and occurrence of a first stroke was evaluated. Individual air pollution exposures were predicted from land-use regression models developed within the European Study of Cohorts for Air Pollution Effects (ESCAPE). The exposures were: PM2.5 [particulate matter (PM) ≤ 2.5 μm in diameter], coarse PM (PM between 2.5 and 10 μm), PM10 (PM ≤ 10 μm), PM2.5 absorbance, nitrogen oxides, and two traffic indicators. Cohort-specific analyses were conducted using Cox proportional hazards models. Random-effects meta-analysis was used for pooled effect estimation. Results: A total of 99,446 study participants were included, 3,086 of whom developed stroke. A 5-μg/m3 increase in annual PM2.5 exposure was associated with 19% increased risk of incident stroke [hazard ratio (HR) = 1.19, 95% CI: 0.88, 1.62]. Similar findings were obtained for PM10. The results were robust to adjustment for an extensive list of cardiovascular risk factors and noise coexposure. The association with PM2.5 was apparent among those ≥ 60 years of age (HR = 1.40, 95% CI: 1.05, 1.87), among never-smokers (HR = 1.74, 95% CI: 1.06, 2.88), and among participants with PM2.5 exposure < 25 μg/m3 (HR = 1.33, 95% CI: 1.01, 1.77). Conclusions: We found suggestive evidence of an association between fine particles and incidence of cerebrovascular events in Europe, even at lower concentrations than set by the current air quality limit value. Citation: Stafoggia M, Cesaroni G, Peters A, Andersen ZJ, Badaloni C, Beelen R, Caracciolo B, Cyrys J, de Faire U, de Hoogh K, Eriksen KT, Fratiglioni L, Galassi C, Gigante B, Havulinna AS, Hennig F, Hilding A, Hoek G, Hoffmann B, Houthuijs D, Korek M, Lanki T, Leander K, Magnusson PK, Meisinger C, Migliore E, Overvad K, Östenson CG, Pedersen NL, Pekkanen J, Penell J, Pershagen G, Pundt N, Pyko A, Raaschou-Nielsen O, Ranzi A, Ricceri F, Sacerdote C, Swart WJ, Turunen AW, Vineis P, Weimar C, Weinmayr G, Wolf K, Brunekreef B, Forastiere F. 2014. Long-term exposure to ambient air pollution and incidence of cerebrovascular events: results from 11 European cohorts within the ESCAPE project. Environ Health Perspect 122:919–925; http://dx.doi.org/10.1289/ehp.1307301

Published
2014
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32. Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE)

Author

Fuks, Kateryna B., Weinmayr, Gudrun, Foraster, Maria, Dratva, Julia, Hampel, Regina, Houthuijs, Danny, Oftedal, Bente, Oudin, Anna, Panasevich, Sviatlana, Penell, Johanna, Sommar, Johan N., Sorensen, Mette, Tiittanen, Pekka, Wolf, Kathrin, Xun, Wei W., Aguilera, Inmaculada, Basagana, Xavier, Beelen, Rob, Bots, Michiel L., Brunekreef, Bert, Bueno-de-Mesquita, H. Bas, Caracciolo, Barbara, Cirach, Marta, de Faire, Ulf, de Nazelle, Audrey, Eeftens, Marloes, Elosua, Roberto, Erbel, Raimund, Forsberg, Bertil, Fratiglioni, Laura, Gaspoz, Jean-Michel, Hilding, Agneta, Jula, Antti, Korek, Michal, Kraemer, Ursula, Kuenzli, Nino, Lanki, Timo, Leander, Karin, Magnusson, Patrik K. E., Marrugat, Jaume, Nieuwenhuijsen, Mark J., Oestenson, Claes-Goeran, Pedersen, Nancy L., Pershagen, Goeran, Phuleria, Harish C., Probst-Hensch, Nicole M., Raaschou-Nielsen, Ole, Schaffner, Emmanuel, Schikowski, Tamara, Schindler, Christian, Schwarze, Per E., Sogaard, Anne J., Sugiri, Dorothea, Swart, Wim J. R., Tsai, Ming-Yi, Turunen, Anu W., Vineis, Paolo, Peters, Annette, Hoffmann, Barbara, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Wolf, Kathrin, Gaspoz, Jean-Michel, Hoffmann, Barbara, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, and IRAS RATIA2

Subjects
Male, Health, Toxicology and Mutagenesis, air pollution, 05 Environmental Sciences, Medizin, Air pollution, VDP::Medisinske fag: 700::Helsefag: 800::Epidemiologi medisinsk og odontologisk statistikk: 803, Review, 030204 cardiovascular system & hematology, 010501 environmental sciences, medicine.disease_cause, Bioinformatics, NO2, Toxicology, 01 natural sciences, 0302 clinical medicine, Risk Factors, USE REGRESSION-MODELS, Medicine, Nitrogen oxides, land use regression (LUR) model, Public, Environmental & Occupational Health, Vehicle Emissions, RISK, education.field_of_study, Air Pollutants, 11 Medical And Health Sciences, ASSOCIATION, 3. Good health, Europe, Noise, Transportation, Female, Nitrogen Oxides, VDP::Midical sciences: 700::Health sciences: 800::Epidemiology, medical and dental statistics: 803, Life Sciences & Biomedicine, PROJECT, Population, Diastole, Environmental Sciences & Ecology, NOx, Land use regression, ESCAPE, 03 medical and health sciences, Arbetsmedicin och miljömedicin, Environmental health, Air Pollution, Humans, PARTICLES, Arterial Pressure, CORONARY-HEART-DISEASE, education, Antihypertensive Agents, METAANALYSIS, 0105 earth and related environmental sciences, ddc:613, Science & Technology, HYPERTENSION, business.industry, Public Health, Environmental and Occupational Health, European population, Odds ratio, Occupational Health and Environmental Health, Environmental Exposure, Blood pressure, Cross-Sectional Studies, ATHEROSCLEROSIS, 13. Climate action, Particulate Matter, business, PRIMARY PREVENTION, Environmental Sciences
Abstract

Background: Long-term exposure to air pollution has been hypothesized to elevate arterial blood pressure (BP). The existing evidence is scarce and country specific. Objectives: We investigated the cross-sectional association of long-term traffic-related air pollution with BP and prevalent hypertension in European populations. Methods: We analyzed 15 population-based cohorts, participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE). We modeled residential exposure to particulate matter and nitrogen oxides with land use regression using a uniform protocol. We assessed traffic exposure with traffic indicator variables. We analyzed systolic and diastolic BP in participants medicated and nonmedicated with BP-lowering medication (BPLM) separately, adjusting for personal and area-level risk factors and environmental noise. Prevalent hypertension was defined as ≥ 140 mmHg systolic BP, or ≥ 90 mmHg diastolic BP, or intake of BPLM. We combined cohort-specific results using random-effects meta-analysis. Results: In the main meta-analysis of 113,926 participants, traffic load on major roads within 100 m of the residence was associated with increased systolic and diastolic BP in nonmedicated participants [0.35 mmHg (95% CI: 0.02, 0.68) and 0.22 mmHg (95% CI: 0.04, 0.40) per 4,000,000 vehicles × m/day, respectively]. The estimated odds ratio (OR) for prevalent hypertension was 1.05 (95% CI: 0.99, 1.11) per 4,000,000 vehicles × m/day. Modeled air pollutants and BP were not clearly associated. Conclusions: In this first comprehensive meta-analysis of European population-based cohorts, we observed a weak positive association of high residential traffic exposure with BP in nonmedicated participants, and an elevated OR for prevalent hypertension. The relationship of modeled air pollutants with BP was inconsistent. Citation: Fuks KB, Weinmayr G, Foraster M, Dratva J, Hampel R, Houthuijs D, Oftedal B, Oudin A, Panasevich S, Penell J, Sommar JN, Sørensen M, Tittanen P, Wolf K, Xun WW, Aguilera I, Basagaña X, Beelen R, Bots ML, Brunekreef B, Bueno-de-Mesquita HB, Caracciolo B, Cirach M, de Faire U, de Nazelle A, Eeftens M, Elosua R, Erbel R, Forsberg B, Fratiglioni L, Gaspoz JM, Hilding A, Jula A, Korek M, Krämer U, Künzli N, Lanki T, Leander K, Magnusson PK, Marrugat J, Nieuwenhuijsen MJ, Östenson CG, Pedersen NL, Pershagen G, Phuleria HC, Probst-Hensch NM, Raaschou-Nielsen O, Schaffner E, Schikowski T, Schindler C, Schwarze PE, Søgaard AJ, Sugiri D, Swart WJ, Tsai MY, Turunen AW, Vineis P, Peters A, Hoffmann B. 2014. Arterial blood pressure and long-term exposure to traffic-related air pollution: an analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE). Environ Health Perspect 122:896–905; http://dx.doi.org/10.1289/ehp.1307725

Published
2014

34. Long-term Exposure to Particulate Matter Constituents and the Incidence of Coronary Events in 11 European Cohorts

Author

LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, IRAS RATIA2, Risk Assessment of Toxic and Immunomodulatory Agents, Wolf, Kathrin, Stafoggia, Massimo, Cesaroni, Giulia, Andersen, Zorana Jovanovic, Beelen, Rob, Galassi, Claudia, Hennig, Frauke, Migliore, Enrica, Penell, Johanna, Ricceri, Fulvio, Sørensen, Mette, Turunen, Anu W, Hampel, Regina, Hoffmann, Barbara, Kälsch, Hagen, Laatikainen, Tiina, Pershagen, Göran, Raaschou-Nielsen, Ole, Sacerdote, Carlotta, Vineis, Paolo, Badaloni, Chiara, Cyrys, Josef, de Hoogh, Kees, Eriksen, Kirsten T, Jedynska, Aleksandra, Keuken, Menno, Kooter, Ingeborg, Lanki, Timo, Ranzi, Andrea, Sugiri, Dorothea, Tsai, Ming-Yi, Wang, Meng, Hoek, Gerard, Brunekreef, Bert, Peters, Annette, Forastiere, Francesco, LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, IRAS RATIA2, Risk Assessment of Toxic and Immunomodulatory Agents, Wolf, Kathrin, Stafoggia, Massimo, Cesaroni, Giulia, Andersen, Zorana Jovanovic, Beelen, Rob, Galassi, Claudia, Hennig, Frauke, Migliore, Enrica, Penell, Johanna, Ricceri, Fulvio, Sørensen, Mette, Turunen, Anu W, Hampel, Regina, Hoffmann, Barbara, Kälsch, Hagen, Laatikainen, Tiina, Pershagen, Göran, Raaschou-Nielsen, Ole, Sacerdote, Carlotta, Vineis, Paolo, Badaloni, Chiara, Cyrys, Josef, de Hoogh, Kees, Eriksen, Kirsten T, Jedynska, Aleksandra, Keuken, Menno, Kooter, Ingeborg, Lanki, Timo, Ranzi, Andrea, Sugiri, Dorothea, Tsai, Ming-Yi, Wang, Meng, Hoek, Gerard, Brunekreef, Bert, Peters, Annette, and Forastiere, Francesco

Published
2015

35. Air Pollution from Road Traffic and Systemic Inflammation in Adults: A Cross-Sectional Analysis in the European ESCAPE Project

Author

IRAS RATIA2, LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, Lanki, Timo, Hampel, Regina, Tiittanen, Pekka, Andrich, Silke, Beelen, Rob, Brunekreef, Bert, Dratva, Julia, De Faire, Ulf, Fuks, Kateryna B, Hoffmann, Barbara, Imboden, Medea, Jousilahti, Pekka, Koenig, Wolfgang, Mahabadi, Amir A, Künzli, Nino, Pedersen, Nancy L, Penell, Johanna, Pershagen, Göran, Probst-Hensch, Nicole M, Schaffner, Emmanuel, Schindler, Christian, Sugiri, Dorothea, Swart, Wim J R, Tsai, Ming-Yi, Turunen, Anu W, Weinmayr, Gudrun, Wolf, Kathrin, Yli-Tuomi, Tarja, Peters, Annette, IRAS RATIA2, LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, Lanki, Timo, Hampel, Regina, Tiittanen, Pekka, Andrich, Silke, Beelen, Rob, Brunekreef, Bert, Dratva, Julia, De Faire, Ulf, Fuks, Kateryna B, Hoffmann, Barbara, Imboden, Medea, Jousilahti, Pekka, Koenig, Wolfgang, Mahabadi, Amir A, Künzli, Nino, Pedersen, Nancy L, Penell, Johanna, Pershagen, Göran, Probst-Hensch, Nicole M, Schaffner, Emmanuel, Schindler, Christian, Sugiri, Dorothea, Swart, Wim J R, Tsai, Ming-Yi, Turunen, Anu W, Weinmayr, Gudrun, Wolf, Kathrin, Yli-Tuomi, Tarja, and Peters, Annette

Published
2015

36. Kodväxling och dess funktioner i klassrummet : en jämförelse mellan svensk- och engelsklärare på gymnasiet

Author

Turunen, Anu

Subjects
luokkakieli, opettaja, vuorovaikutus, ruotsin kieli, luokkaopetus, koodinvaihto, funktio, kvalitatiivinen analyysi, kieltenopettajat, luokkahuonevuorovaikutus, haastattelu, observointi, kielten opetus, englannin kieli
Abstract

Tämän tutkielman päämääränä oli selvittää, missä tilanteissa ruotsin- ja englanninopettajat käyttävät koodinvaihtoa lukiotunneilla ja millaisia funktioita näillä vaihdoilla on. Lisäksi haluttiin tutkia, eroavatko ruotsin- ja englanninopettajien tavat käyttää koodinvaihtoa toisistaan. Materiaali tutkimusta varten kerättiin observoimalla 16 lukiotuntia, joista 8 ruotsin- ja 8 englannintuntia. Observoinnin apuna käytettiin observointilomaketta, johon merkittiin, mistä kielestä mihin opettaja vaihtoi ja mikä funktio vaihdon taustalla oli. Lisäksi observointien aikana tehtiin kenttämuistiinpanoja. Jotta tutkimustuloksiin saataisiin toinen näkökulma, haastateltiin 3 ruotsin- ja 3 englanninopettajaa. Haastatteluissa opettajat vastasivat kysymyksiin luokkakielestä yleensä sekä koodinvaihdosta. Tulokset osoittivat, että ruotsinopettajat vaihtoivat koodia selvästi englanninopettajia enemmän. Useimmiten ruotsinopettajat vaihtoivat koodia kun he opettivat kielioppia, antoivat ohjeita tehtävien tekemiseen ja kun tehtäviä tarkastettiin kun taas englanninopettajat hyödynsivät koodinvaihtoa vastatessaan oppilaiden kysymyksiin, opettaessaan kielioppia ja tehtäviä tarkastettaessa. Koodinvaihdolla oli useita funktioita. Ruotsinopettajat yleensä käänsivät ja toistivat sanoja tai lauseita, englanninopettajat halusivat selittää ja laajentaa sanojen sekä fraasien merkityksiä. Haastatteluihin osallistuneet opettajat totesivat, että koodinvaihdon tärkein tarkoitus on tukea oppilaiden kieltenoppimista ja varmistaa, että kaikki oppilaat ymmärtävät ja pysyvät mukana opetuksessa. Tutkimus osoitti, että lukion ruotsin- ja englanninopettajien luokkakielenkäytössä on jonkin verran eroja. Suurimpana erona voidaan mainita kohdekielen käyttö, joka oli englannin opettajilla ruotsinopettajia laajempaa. Englanninopettajat käyttivät englantia sekä opetuksessa että keskustellessaan vapaammin oppilaitten kanssa kun taas ruotsinopettajat käyttivät ruotsia eniten rutiininomaisissa luokkahuonetilanteissa ja vaihtoivat kielen suomeen oppilaille jutellessaan.

Published
2013

37. Att tala förståeligt. Gymnasieelevernas och lärarnas åsikter om svenskt uttal och uttalsövningar

Author

Turunen, Anu

Subjects
läroplan, uttal, undervisning
Abstract

Tutkielmani tarkoitus oli selvittää, mitä mieltä lukiolaiset ovat ruotsin kielen ääntämisharjoituksista ja niiden riittävyydestä, sekä ottaa selville heidän yleinen kantansa ruotsin kielen opiskelusta. Tutkimuksessa huomioitiin myös, kuinka sukupuoli ja aiempi menestys opinnoissa vaikuttivat vastauksiin. Tämän lisäksi lukio-opettajilta kysyttiin, millaisia ääntämisharjoituksia he käyttävät opetuksessaan. Tutkimus oli kvalitatiivinen ja materiaali koottiin lomakkeiden avulla. Kyselylomakkeita oli kaksi, joista toinen oli oppilaita ja toinen opettajia varten. Tutkimukseen osallistui yhteensä 110 lukiolaista ja 4 opettajaa eri puolilta Suomea. Tuloksista ilmeni, että vain 36,1 % kyselyyn vastanneista lukiolaisista halusi lisää ääntämisenopetusta. Positiivisesti yllättävää oli, että 61,9 % lukiolaisista piti ruotsin opiskelusta. Sukupuoli ja saadut arvosanat vaikuttivat merkittävästi vastauksiin – tytöt ja hyvin menestyneet halusivat enemmän ääntämisen opetusta ja pitivät enemmän ruotsin kielen opiskelusta kuin muut vastaajat. Opettajien vastauksista kävi ilmi, että ääntäminen ja ääntämisharjoitukset ovat tärkeä osa kielenopetusta. Sekä oppilaiden että opettajien mielestä tärkeimmät kriteerit ääntämistä koskien olivat selkeys ja ymmärrettävyys. Tutkimuksen perusteella ääntämisharjoitusten roolia opetussuunnitelmassa tulisi muuttaa näkyvämmäksi. Vaikka vain hieman yli kolmasosa lukiolaisista halusi lisää ääntämisenopettamista, tulisi opettajien harkita, miten he opettavat ääntämistä ja ovatko opetustavat tehokkaita.

Published
2011

39. Long-Term Exposure to Ambient Air Pollution and Incidence of Cerebrovascular Events:Results from 11 European Cohorts within the ESCAPE Project

Author

Stafoggia, Massimo, Cesaroni, Giulia, Peters, Annette, Andersen, Zorana Jovanovic, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, Cyrys, Josef, de Faire, Ulf, de Hoogh, Kees, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Gigante, Bruna, Havulinna, Aki S, Hennig, Frauke, Hilding, Agneta, Hoek, Gerard, Hoffmann, Barbara, Houthuijs, Danny, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K, Meisinger, Christa, Migliore, Enrica, Overvad, Kim, Ostenson, Claes-Göran, Pedersen, Nancy L, Pekkanen, Juha, Penell, Johanna, Pershagen, Göran, Pundt, Noreen, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Swart, Wim J, Turunen, Anu W, Vineis, Paolo, Weimar, Christian, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Forastiere, Francesco, Stafoggia, Massimo, Cesaroni, Giulia, Peters, Annette, Andersen, Zorana Jovanovic, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, Cyrys, Josef, de Faire, Ulf, de Hoogh, Kees, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Gigante, Bruna, Havulinna, Aki S, Hennig, Frauke, Hilding, Agneta, Hoek, Gerard, Hoffmann, Barbara, Houthuijs, Danny, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K, Meisinger, Christa, Migliore, Enrica, Overvad, Kim, Ostenson, Claes-Göran, Pedersen, Nancy L, Pekkanen, Juha, Penell, Johanna, Pershagen, Göran, Pundt, Noreen, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Swart, Wim J, Turunen, Anu W, Vineis, Paolo, Weimar, Christian, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, and Forastiere, Francesco

Abstract

BACKGROUND: Few studies have investigated effects of air pollution on the incidence of cerebrovascular events.OBJECTIVES: We assessed the association between long-term exposure to multiple air pollutants and the incidence of stroke in European cohorts.METHODS: Data from 11 cohorts were collected and occurrence of a first stroke was evaluated. Individual air pollution exposures were predicted from land-use regression models developed within the "European Study of Cohorts for Air Pollution Effects" (ESCAPE). The exposures were: PM2.5 (particulate matter [PM] below 2.5 µm in diameter), coarse PM (PM between 2.5 and 10 µm), PM10 (PM below 10 µm), PM2.5 absorbance, nitrogen oxides, and two traffic indicators. Cohort-specific analyses were conducted using Cox proportional hazards models. Random-effects meta-analysis was used for pooled effect estimation.RESULTS: 99,446 subjects were included, 3,086 of whom developed stroke. A 5-μg/m(3) increase in annual PM2.5 exposure was associated with 19% increased risk of incident stroke (hazard ratio [HR] = 1.19, 95% confidence interval [CI]: 0.88, 1.62). Similar findings were obtained for PM10. The results were robust to adjustment for an extensive list of cardiovascular risk factors and noise co-exposure. The association with PM2.5 was apparent among those aged 60+ years (HR = 1.40, 95% CI: 1.05, 1.87), among never-smokers (HR = 1.74, 95% CI: 1.06, 2.88), and among subjects with PM2.5 exposure below 25 μg/m(3) (HR = 1.33, 95% CI: 1.01, 1.77).CONCLUSIONS: We found suggestive evidence of an association between fine particles and incidence of cerebrovascular events in Europe, even at lower concentrations than set by the current air quality limit value.

Published
2014

40. Air Pollution and Non-Malignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project

Author

Dimakopoulou, Konstantina, Samoli, Evangelia, Beelen, Rob, Stafoggia, Massimo, Jovanovic Andersen, Zorana, Hoffmann, Barbara, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei, Hoek, Gerard, Raaschou-Nielsen, Ole, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Jousilahti, Pekka, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nafstad, Per, Schwarze, Per E, Penell, Johanna, Fratiglioni, Laura, Andersson, Niklas, Pedersen, Nancy, Korek, Michal, De Faire, Ulf, Thorup Eriksen, Kirsten, Tjønneland, Anne, Becker, Thomas, Wang, Meng, Bueno-de-Mesquita, Bas, Tsai, Ming-Yi, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Marcon, Alessandro, Krämer, Ursula, Kuhlbusch, Thomas Aj, Vossoughi, Mohammad, Key, Timothy, de Hoogh, Kees, Hampel, Regina, Peters, Annette, Heinrich, Joachim, Weinmayr, Gudrun, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Jacquemin, Bénédicte, Stempfelet, Morgane, Vilier, Alice, Ricceri, Fulvio, Sacerdote, Carlotta, Pedeli, Xanthi, Katsoulis, Michalis, Trichopoulou, Antonia, Brunekreef, Bert, Katsouyanni, Klea, Dimakopoulou, Konstantina, Samoli, Evangelia, Beelen, Rob, Stafoggia, Massimo, Jovanovic Andersen, Zorana, Hoffmann, Barbara, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei, Hoek, Gerard, Raaschou-Nielsen, Ole, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Jousilahti, Pekka, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nafstad, Per, Schwarze, Per E, Penell, Johanna, Fratiglioni, Laura, Andersson, Niklas, Pedersen, Nancy, Korek, Michal, De Faire, Ulf, Thorup Eriksen, Kirsten, Tjønneland, Anne, Becker, Thomas, Wang, Meng, Bueno-de-Mesquita, Bas, Tsai, Ming-Yi, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Marcon, Alessandro, Krämer, Ursula, Kuhlbusch, Thomas Aj, Vossoughi, Mohammad, Key, Timothy, de Hoogh, Kees, Hampel, Regina, Peters, Annette, Heinrich, Joachim, Weinmayr, Gudrun, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Jacquemin, Bénédicte, Stempfelet, Morgane, Vilier, Alice, Ricceri, Fulvio, Sacerdote, Carlotta, Pedeli, Xanthi, Katsoulis, Michalis, Trichopoulou, Antonia, Brunekreef, Bert, and Katsouyanni, Klea

Abstract

Rationale: Prospective cohort studies have shown that chronic exposure to particulate matter and traffic related air pollution is associated with reduced survival. However, the effects on non-malignant respiratory mortality are less studied and those reported are less consistent. Objectives: We have investigated the relationship of long-term exposure to air pollution and non-malignant respiratory mortality in 16 cohorts with individual level data within the multi center European Study of Cohorts for Air Pollution Effects (ESCAPE). Methods: Data from 16 ongoing cohort studies from Europe were used. The total number of subjects was 307,553. There were 1,559 respiratory deaths during follow-up. Measurements: Air pollution exposure was estimated by land use regression models at the baseline residential addresses of study participants and traffic-proximity variables were derived from geographical databases, following a standardized procedure within ESCAPE study. Cohort-specific hazard ratios obtained by Cox proportional hazard models from standardized individual cohort analyses were combined using meta-analyses. Main Results: We found no significant associations between air pollution exposure and non-malignant respiratory mortality. Most hazard ratios were slightly below unity, with the exception of the traffic-proximity indicators. Conclusions: In this study of 16 cohorts there was no association between air pollution exposure and non malignant respiratory mortality.

Published
2014
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41. Air Pollution and Nonmalignant Respiratory Mortality in 16 Cohorts within the ESCAPE Project

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Dimakopoulou, Konstantina, Samoli, Evangelia, Beelen, Rob, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei, Hoek, Gerard, Raaschou-Nielsen, Ole, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Jousilahti, Pekka, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nafstad, Per, Schwarze, Per E., Penell, Johanna, Fratiglioni, Laura, Andersson, Niklas, Pedersen, Nancy, Korek, Michal, De Faire, Ulf, Eriksen, Kirsten Thorup, Tjonneland, Anne, Becker, Thomas, Wang, Meng, Bueno-de-Mesquita, Bas, Tsai, Ming-Yi, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Marcon, Alessandro, Kramer, Ursula, Kuhlbusch, Thomas A. J., Vossoughi, Mohammad, Key, Timothy, de Hoogh, Kees, Hampel, Regina, Peters, Annette, Heinrich, Joachim, Weinmayr, Gudrun, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Jacquemin, Benedicte, Stempfelet, Morgane, Vilier, Alice, Ricceri, Fulvio, Sacerdote, Carlotta, Pedeli, Xanthi, Katsoulis, Michalis, Trichopoulou, Antonia, Brunekreef, Bert, Katsouyanni, Klea, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Dimakopoulou, Konstantina, Samoli, Evangelia, Beelen, Rob, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei, Hoek, Gerard, Raaschou-Nielsen, Ole, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Jousilahti, Pekka, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nafstad, Per, Schwarze, Per E., Penell, Johanna, Fratiglioni, Laura, Andersson, Niklas, Pedersen, Nancy, Korek, Michal, De Faire, Ulf, Eriksen, Kirsten Thorup, Tjonneland, Anne, Becker, Thomas, Wang, Meng, Bueno-de-Mesquita, Bas, Tsai, Ming-Yi, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Marcon, Alessandro, Kramer, Ursula, Kuhlbusch, Thomas A. J., Vossoughi, Mohammad, Key, Timothy, de Hoogh, Kees, Hampel, Regina, Peters, Annette, Heinrich, Joachim, Weinmayr, Gudrun, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Jacquemin, Benedicte, Stempfelet, Morgane, Vilier, Alice, Ricceri, Fulvio, Sacerdote, Carlotta, Pedeli, Xanthi, Katsoulis, Michalis, Trichopoulou, Antonia, Brunekreef, Bert, and Katsouyanni, Klea

Published
2014

42. Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W., Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S., Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L., Ostenson, Claes-Goeran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Goeran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Kraemer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Kuenzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Francoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, Hoek, Gerard, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W., Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S., Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L., Ostenson, Claes-Goeran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Goeran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Kraemer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Kuenzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Francoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Published
2014

43. Long-Term Exposure to Ambient Air Pollution and Incidence of Cerebrovascular Events: Results from 11 European Cohorts within the ESCAPE Project

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Stafoggia, Massimo, Cesaroni, Giulia, Peters, Annette, Andersen, Zorana J., Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, Cyrys, Josef, de Faire, Ulf, de Hoogh, Kees, Eriksen, Kirsten T., Fratiglioni, Laura, Galassi, Claudia, Gigante, Bruna, Havulinna, Aki S., Hennig, Frauke, Hilding, Agneta, Hoek, Gerard, Hoffmann, Barbara, Houthuijs, Danny, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K., Meisinger, Christa, Migliore, Enrica, Overvad, Kim, Ostenson, Claes-Goran, Pedersen, Nancy L., Pekkanen, Juha, Penell, Johanna, Pershagen, Goran, Pundt, Noreen, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Swart, Wim J. R., Turunen, Anu W., Vineis, Paolo, Weimar, Christian, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, Forastiere, Francesco, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Stafoggia, Massimo, Cesaroni, Giulia, Peters, Annette, Andersen, Zorana J., Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, Cyrys, Josef, de Faire, Ulf, de Hoogh, Kees, Eriksen, Kirsten T., Fratiglioni, Laura, Galassi, Claudia, Gigante, Bruna, Havulinna, Aki S., Hennig, Frauke, Hilding, Agneta, Hoek, Gerard, Hoffmann, Barbara, Houthuijs, Danny, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K., Meisinger, Christa, Migliore, Enrica, Overvad, Kim, Ostenson, Claes-Goran, Pedersen, Nancy L., Pekkanen, Juha, Penell, Johanna, Pershagen, Goran, Pundt, Noreen, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Swart, Wim J. R., Turunen, Anu W., Vineis, Paolo, Weimar, Christian, Weinmayr, Gudrun, Wolf, Kathrin, Brunekreef, Bert, and Forastiere, Francesco

Published
2014

44. Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project.

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Cesaroni, Giulia, Forastiere, Francesco, Stafoggia, Massimo, Andersen, Zorana J, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, de Faire, Ulf, Erbel, Raimund, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Hampel, Regina, Heier, Margit, Hennig, Frauke, Hilding, Agneta, Hoffmann, Barbara, Houthuijs, Danny, Jöckel, Karl-Heinz, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K E, Migliore, Enrica, Ostenson, Caes-Göran, Overvad, Kim, Pedersen, Nancy L, J, Juha Pekkanen, Penell, Johanna, Pershagen, Göran, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Salomaa, Veikko, Swart, Wim, Turunen, Anu W, Vineis, Paolo, Weinmayr, Gudrun, Wolf, Kathrin, de Hoogh, Kees, Hoek, Gerard, Brunekreef, Bert, Peters, Annette, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Cesaroni, Giulia, Forastiere, Francesco, Stafoggia, Massimo, Andersen, Zorana J, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, de Faire, Ulf, Erbel, Raimund, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Hampel, Regina, Heier, Margit, Hennig, Frauke, Hilding, Agneta, Hoffmann, Barbara, Houthuijs, Danny, Jöckel, Karl-Heinz, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K E, Migliore, Enrica, Ostenson, Caes-Göran, Overvad, Kim, Pedersen, Nancy L, J, Juha Pekkanen, Penell, Johanna, Pershagen, Göran, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Salomaa, Veikko, Swart, Wim, Turunen, Anu W, Vineis, Paolo, Weinmayr, Gudrun, Wolf, Kathrin, de Hoogh, Kees, Hoek, Gerard, Brunekreef, Bert, and Peters, Annette

Published
2014

45. Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts: Results from the ESCAPE and TRANSPHORM projects

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W., Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W., Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Goran, Pedersen, Nancy L., Ostenson, Claes-Goran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sorensen, Mette, Tjonneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L., Meliefste, Kees, Kraemer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Kuenzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Francoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M., Kukkonen, Jaakko, Sokhi, Ranjeet S., Brunekreef, Bert, Katsouyanni, Klea, Hoek, Gerard, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W., Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W., Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Goran, Pedersen, Nancy L., Ostenson, Claes-Goran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sorensen, Mette, Tjonneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L., Meliefste, Kees, Kraemer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Kuenzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Francoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M., Kukkonen, Jaakko, Sokhi, Ranjeet S., Brunekreef, Bert, Katsouyanni, Klea, and Hoek, Gerard

Published
2014

46. Arterial Blood Pressure and Long-Term Exposure to Traffic-Related Air Pollution: An Analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE)

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Fuks, Kateryna B., Weinmayr, Gudrun, Foraster, Maria, Dratva, Julia, Hampel, Regina, Houthuijs, Danny, Oftedal, Bente, Oudin, Anna, Panasevich, Sviatlana, Penell, Johanna, Sommar, Johan N., Sorensen, Mette, Tiittanen, Pekka, Wolf, Kathrin, Xun, Wei W., Aguilera, Inmaculada, Basagana, Xavier, Beelen, Rob, Bots, Michiel L., Brunekreef, Bert, Bueno-de-Mesquita, H. Bas, Caracciolo, Barbara, Cirach, Marta, de Faire, Ulf, de Nazelle, Audrey, Eeftens, Marloes, Elosua, Roberto, Erbel, Raimund, Forsberg, Bertil, Fratiglioni, Laura, Gaspoz, Jean-Michel, Hilding, Agneta, Jula, Antti, Korek, Michal, Kraemer, Ursula, Kuenzli, Nino, Lanki, Timo, Leander, Karin, Magnusson, Patrik K. E., Marrugat, Jaume, Nieuwenhuijsen, Mark J., Oestenson, Claes-Goeran, Pedersen, Nancy L., Pershagen, Goeran, Phuleria, Harish C., Probst-Hensch, Nicole M., Raaschou-Nielsen, Ole, Schaffner, Emmanuel, Schikowski, Tamara, Schindler, Christian, Schwarze, Per E., Sogaard, Anne J., Sugiri, Dorothea, Swart, Wim J. R., Tsai, Ming-Yi, Turunen, Anu W., Vineis, Paolo, Peters, Annette, Hoffmann, Barbara, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Fuks, Kateryna B., Weinmayr, Gudrun, Foraster, Maria, Dratva, Julia, Hampel, Regina, Houthuijs, Danny, Oftedal, Bente, Oudin, Anna, Panasevich, Sviatlana, Penell, Johanna, Sommar, Johan N., Sorensen, Mette, Tiittanen, Pekka, Wolf, Kathrin, Xun, Wei W., Aguilera, Inmaculada, Basagana, Xavier, Beelen, Rob, Bots, Michiel L., Brunekreef, Bert, Bueno-de-Mesquita, H. Bas, Caracciolo, Barbara, Cirach, Marta, de Faire, Ulf, de Nazelle, Audrey, Eeftens, Marloes, Elosua, Roberto, Erbel, Raimund, Forsberg, Bertil, Fratiglioni, Laura, Gaspoz, Jean-Michel, Hilding, Agneta, Jula, Antti, Korek, Michal, Kraemer, Ursula, Kuenzli, Nino, Lanki, Timo, Leander, Karin, Magnusson, Patrik K. E., Marrugat, Jaume, Nieuwenhuijsen, Mark J., Oestenson, Claes-Goeran, Pedersen, Nancy L., Pershagen, Goeran, Phuleria, Harish C., Probst-Hensch, Nicole M., Raaschou-Nielsen, Ole, Schaffner, Emmanuel, Schikowski, Tamara, Schindler, Christian, Schwarze, Per E., Sogaard, Anne J., Sugiri, Dorothea, Swart, Wim J. R., Tsai, Ming-Yi, Turunen, Anu W., Vineis, Paolo, Peters, Annette, and Hoffmann, Barbara

Published
2014

47. Long-term exposure to elemental constituents of particulate matter and cardiovascular mortality in 19 European cohorts:Results from the ESCAPE and TRANSPHORM projects

Author

Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W, Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W, Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Göran, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sørensen, Mette, Tjønneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L, Meliefste, Kees, Krämer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Künzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Françoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M, Kukkonen, Jaakko, Sokhi, Ranjeet S, Brunekreef, Bert, Katsouyanni, Klea, Hoek, Gerard, Wang, Meng, Beelen, Rob, Stafoggia, Massimo, Raaschou-Nielsen, Ole, Andersen, Zorana Jovanovic, Hoffmann, Barbara, Fischer, Paul, Houthuijs, Danny, Nieuwenhuijsen, Mark, Weinmayr, Gudrun, Vineis, Paolo, Xun, Wei W, Dimakopoulou, Konstantina, Samoli, Evangelia, Laatikainen, Tiina, Lanki, Timo, Turunen, Anu W, Oftedal, Bente, Schwarze, Per, Aamodt, Geir, Penell, Johanna, De Faire, Ulf, Korek, Michal, Leander, Karin, Pershagen, Göran, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Eriksen, Kirsten Thorup, Sørensen, Mette, Tjønneland, Anne, Bueno-de-Mesquita, Bas, Eeftens, Marloes, Bots, Michiel L, Meliefste, Kees, Krämer, Ursula, Heinrich, Joachim, Sugiri, Dorothea, Key, Timothy, de Hoogh, Kees, Wolf, Kathrin, Peters, Annette, Cyrys, Josef, Jaensch, Andrea, Concin, Hans, Nagel, Gabriele, Tsai, Ming-Yi, Phuleria, Harish, Ineichen, Alex, Künzli, Nino, Probst-Hensch, Nicole, Schaffner, Emmanuel, Vilier, Alice, Clavel-Chapelon, Françoise, Declerq, Christophe, Ricceri, Fulvio, Sacerdote, Carlotta, Marcon, Alessandro, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Katsoulis, Michail, Trichopoulou, Antonia, Keuken, Menno, Jedynska, Aleksandra, Kooter, Ingeborg M, Kukkonen, Jaakko, Sokhi, Ranjeet S, Brunekreef, Bert, Katsouyanni, Klea, and Hoek, Gerard

Abstract

Associations between long-term exposure to ambient particulate matter (PM) and cardiovascular (CVD) mortality have been widely recognized. However, health effects of long-term exposure to constituents of PM on total CVD mortality have been explored in a single study only.

Published
2014

48. Long term exposure to ambient air pollution and incidence of acute coronary events:prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project

Author

Cesaroni, Giulia, Forastiere, Francesco, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, de Faire, Ulf, Erbel, Raimund, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Hampel, Regina, Heier, Margit, Hennig, Frauke, Hilding, Agneta, Hoffmann, Barbara, Houthuijs, Danny, Jöckel, Karl-Heinz, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K E, Migliore, Enrica, Ostenson, Caes-Göran, Overvad, Kim, Pedersen, Nancy L, J, Juha Pekkanen, Penell, Johanna, Pershagen, Göran, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Salomaa, Veikko, Swart, Wim, Turunen, Anu W, Vineis, Paolo, Weinmayr, Gudrun, Wolf, Kathrin, de Hoogh, Kees, Hoek, Gerard, Brunekreef, Bert, Peters, Annette, Cesaroni, Giulia, Forastiere, Francesco, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Badaloni, Chiara, Beelen, Rob, Caracciolo, Barbara, de Faire, Ulf, Erbel, Raimund, Eriksen, Kirsten T, Fratiglioni, Laura, Galassi, Claudia, Hampel, Regina, Heier, Margit, Hennig, Frauke, Hilding, Agneta, Hoffmann, Barbara, Houthuijs, Danny, Jöckel, Karl-Heinz, Korek, Michal, Lanki, Timo, Leander, Karin, Magnusson, Patrik K E, Migliore, Enrica, Ostenson, Caes-Göran, Overvad, Kim, Pedersen, Nancy L, J, Juha Pekkanen, Penell, Johanna, Pershagen, Göran, Pyko, Andrei, Raaschou-Nielsen, Ole, Ranzi, Andrea, Ricceri, Fulvio, Sacerdote, Carlotta, Salomaa, Veikko, Swart, Wim, Turunen, Anu W, Vineis, Paolo, Weinmayr, Gudrun, Wolf, Kathrin, de Hoogh, Kees, Hoek, Gerard, Brunekreef, Bert, and Peters, Annette

Abstract

To study the effect of long term exposure to airborne pollutants on the incidence of acute coronary events in 11 cohorts participating in the European Study of Cohorts for Air Pollution Effects (ESCAPE).

Published
2014

49. Itseohjautuvana verkossa

Author

TURUNEN, ANU, Kasvatustieteiden laitos - Department of Education, Kasvatustieteiden tiedekunta - Faculty of Education, and University of Tampere

Subjects
Aikuiskasvatus - Adult Education
Published
2004

50. Effects of long-term exposure to air pollution on natural-cause mortality:an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, Hoek, Gerard, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Abstract

Few studies on long-term exposure to air pollution and mortality have been reported from Europe. Within the multicentre European Study of Cohorts for Air Pollution Effects (ESCAPE), we aimed to investigate the association between natural-cause mortality and long-term exposure to several air pollutants.

Published
2013

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