239 results on '"Tyson, Darren R."'
Search Results
2. Identifying mechanisms driving the early response of triple negative breast cancer patients to neoadjuvant chemotherapy using a mechanistic model integrating in vitro and in vivo imaging data
3. A community-based approach to image analysis of cells, tissues and tumors
4. Purinergic Ca 2+ Signaling as a Novel Mechanism of Drug Tolerance in BRAF-Mutant Melanoma.
5. Beyond Programmed Death-Ligand 1: B7-H6 Emerges as a Potential Immunotherapy Target in SCLC
6. An unbiased metric of antiproliferative drug effect in vitro
7. Purinergic calcium signaling drives drug tolerance through ERK reactivation in BRAF-mutant melanoma
8. The contribution of age structure to cell population responses to targeted therapeutics
9. A global sensitivity analysis of a mechanistic model of neoadjuvant chemotherapy for triple negative breast cancer constrained by in vitro and in vivo imaging data
10. Abstract B036: Treatment modalities in KRAS-driven cancer
11. Abstract A032: Targeting RAS beyond KRAS, a review
12. Data from Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer
13. Supplementary Table 1 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
14. Supplementary Figure 2 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
15. Supplementary Figure 1 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
16. Supplementary Figures from Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer
17. Supplementary Tables from Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer
18. Supplementary Figure 3 from Reverse-Phase Protein Array Profiling of Oropharyngeal Cancer and Significance of PIK3CA Mutations in HPV-Associated Head and Neck Cancer
19. Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity
20. Involvement of epithelial-mesenchymal transition genes in small cell lung cancer phenotypic plasticity
21. Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer
22. Proteomics of Cancer of Hormone-Dependent Tissues
23. Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines
24. Utilizing Three-Dimensional Culture Methods to Improve High-Throughput Drug Screening in Anaplastic Thyroid Carcinoma
25. Abstract P1-08-20: In silico analysis of a novel mathematical model integrating in vitro and in vivo imaging data reveals driving mechanisms of breast cancer response to NAT for personalized tumor forecasting
26. A heterogeneous drug tolerant persister state in BRAF-mutant melanoma is characterized by ion channel dysregulation and susceptibility to ferroptosis
27. Dependence On Glycolysis Sensitizes BRAF-mutated Melanomas For Increased Response To Targeted BRAF Inhibition
28. Response of Head and Neck Squamous Cell Carcinoma Cells Carrying PIK3CA Mutations to Selected Targeted Therapies
29. Periprostatic Adipose Tissue as a Modulator of Prostate Cancer Aggressiveness
30. An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability
31. Thunor: visualization and analysis of high-throughput dose–response datasets
32. Bone marrow stem cells for urologic tissue engineering
33. Abstract PS13-44: Identifying relevant parameters that characterize the early response to NAT in breast cancer patients using a novel personalized mechanistic model integrating in vitro and in vivo imaging data
34. Beyond genetics in personalized cancer treatment: assessing dynamics and heterogeneity of tumor responses
35. Transmembrane Receptor Oligomerization
36. Proteomics for the identification of new prostate cancer biomarkers
37. Trait Variability of Cancer Cells Quantified by High-Content Automated Microscopy of Single Cells
38. ACDC: Automated Cell Detection and Counting for Time-Lapse Fluorescence Microscopy
39. A unifying framework disentangles genetic, epigenetic, and stochastic sources of drug-response variability in anin vitromodel of tumor heterogeneity
40. Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers
41. Loss of annexin A1 disrupts normal prostate glandular structure by inducing autocrine IL-6 signaling
42. Long-Term Impact of a Robot Assisted Laparoscopic Prostatectomy Mini Fellowship Training Program on Postgraduate Urological Practice Patterns
43. REDUCED ANNEXIN A1 EXPRESSION CONTRIBUTES TO PROSTATE CANCER BY ACTIVATION OF AKT AND INDUCTION OF IL-6: 1229
44. COMPARATIVE ANALYSIS OF GENE EXPRESSION SIGUNATURES OF 3-D CULTURE SPECIFIC GENES AND EPITHELIAL SPECIFIC GENES FROM CLINICALY LOCALIZED HUMAN PROSTATE NORMAL AND CANCER SPECIMENS: 1236
45. DIFFERENTIAL GENE EXPRESSION AND LIGAND-INDUCED SIGNAL TRANSDUCTION IN THREE-DIMENSIONAL PROSTATIC EPITHELIAL CELL CULTURE: 547
46. Visualization and analysis of high-throughput in vitro dose–response datasets with Thunor
47. Transmembrane Receptor Oligomerization
48. Culture Requirements of Prostatic Epithelial Cell Lines for Acinar Morphogenesis and Lumen Formation In Vitro: Role of Extracellular Calcium
49. The Impact of Altered Annexin I Protein Levels on Apoptosis and Signal Transduction Pathways in Prostate Cancer Cells
50. PTH Induction of Transcriptional Activity of the cAMP Response Element-Binding Protein Requires the Serine 129 Site and Glycogen Synthase Kinase-3 Activity, But Not Casein Kinase II Sites
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