58 results on '"U. Okonkwo"'
Search Results
2. An artificial neural network visible mathematical model for predicting slug liquid holdup in low to high viscosity multiphase flow for horizontal to vertical pipes
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Chibuzo Cosmas Nwanwe, Ugochukwu Ilozurike Duru, Charley Iyke C. Anyadiegwu, Azunna I. B. Ekejuba, Stanley I. Onwukwe, Angela N. Nwachukwu, and Boniface U. Okonkwo
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Artificial neural network ,Slug liquid holdup ,Visible mathematical model ,Black-box model ,Linear activation function ,Hyperbolic tangent activation function ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Abstract Slug liquid holdup (SLH) is a critical requirement for accurate pressure drop prediction during multiphase pipe flows and by extension optimal gas lift design and production optimization in wellbores. Existing empirical correlations provide inaccurate predictions because they were developed with regression analysis and data measured for limited ranges of flow conditions. Existing SLH machine learning models provide accurate predictions but are published without any equations making their use by other researchers difficult. The only existing ML model published with actual equations cannot be considered optimum because it was selected by considering artificial neural network (ANN) structures with only one hidden layer. In this study, an ANN-based model for SLH prediction with actual equations is presented. A total of 2699 data points randomly divided into 70%, 15%, and 15% for training, validation, and testing was used in constructing 71 different network structures with 1, 2, and 3 hidden layers respectively. Sensitivity analysis revealed that the optimum network structure has 3 hidden layers with 20, 5, and 15 neurons in the first, second, and third hidden layers, respectively. The optimum network structure was translated into actual equations with the aid of the weights, biases, and activation functions. Trend analysis revealed that this study’s model reproduced the expected effects of inputs on SLH. Test against measured data revealed that this study’s model is in agreement with measured data with coefficient of determinations of 0.9791, 0.9727, 0.9756, and 0.9776 for training, testing, validation, and entire datasets, respectively. Comparative study revealed that this study’s model outperformed existing models with a relative performance factor of 0.002. The present model is presented with visible mathematical equations making its implementation by any user easy and without the need for any ML framework. Unlike existing ANN-based models developed with one hidden layered ANN structures, the present model was developed by considering ANN structures with one, two, and three hidden layers, respectively.
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- 2024
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3. Effect of a maternal infant HIV care clinic for HIV-infected mothers and exposed infants on follow up postnatal HIV testing and care in Southeastern Nigeria: A retrospective review
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A. Nwandu, D. Watson, J. Ilozumba, J. Egharevba, A. Osuji, C. Onuoha, U. Okonkwo, C. Ezeaku, O. Mbah, I. Okafor, and E. Justin
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Infectious and parasitic diseases ,RC109-216 ,Public aspects of medicine ,RA1-1270 - Published
- 2016
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4. Sources and Functionality of Rural Water Supply in Communities from three Senatorial Zones of Imo State, Nigeria
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I. E. Mbuka-Nwosu, L. N. Muoghalu, and A. U. Okonkwo
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Rural water supply ,domestic water access ,environmental management ,good health ,Science - Abstract
Sustainability of domestic water access in communities is essential for good health, society’s dignity and progress. This study investigated the sources and functionality of rural water supply in nine communities of three local government area (LGA) in three senatorial zones of Imo State, Nigeria using structured questionnaires. The questionnaires were administered on 100 women in each community. Data obtained were analysed using multivariate analysis of variance (MANOVA) to reveal the frequency of using the various sources of rural water supply, and Wilcoxon’s test for matched pairs to reveal the functionality status of the most frequently used water source. The findings indicate the importance of borehole water facilities in these rural communities and the necessity for intervention programs to strengthen their functionality in tandem with the State’s aspirations in achieving sustainable development goals.
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- 2022
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5. Determinants of Volume of POME Generation in Palm Oil Mills for Planning Wastewater Recovery in Biogas Energy Development
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E. B. Tambe, A. U. Okonkwo, and L. C. Eme
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POME dynamics ,independent variables ,volumetric vessels ,bioenergy ,ADAPALMS ,Science - Abstract
Wastewater volume is a necessary prerequisite for planning transformation to valuable resource and averting environmental degradation. This study investigated the dynamics of POME volume generation in palm oil mills in relation to types of fresh fruit bunches (FFBs), seasons, milling scales and volume of crude palm oil (CPO) produced in ADAPALMS and catchment communities, Ohaji/Egbema LGA, Imo State. The eight catchment communities of ADAPALMS were categorised into three strata in relation to the number of small-scale mills in each community (1-5mills, 6-10mills, and 11-15mills). In each stratum, a community was randomly sampled. A total of nine small-scale mills were sampled from the three sampled communities (Ohoba, Amafor and Etekwuru) in proportion to the average number of mills in each stratum. The lone medium and large scale mill (ADAPLAMS) in the study area represented the other scales of milling. For small and medium scale mills, the volume of POME generated was measured from the dimensions of the vessels where POME was stored, while that of large scale mill was obtained from industrial records. Data was analysed using multiple linear regression of SPSS. The volume of POME generated is significantly related to milling scales and volume of CPO produced (p< 0.01); R2=0.788. Within small scale mills, the volume of POME is significantly related to types of FFBs (p< 0.01), different small milling scales (p< 0.05), and volume of CPO produced (p< 0.01); R2=0.762. Thus, these independent variables are the principal determinants of POME volume generation in the area. The result has implication on the necessity of predictive models in managing the dynamics of POME volumes for efficient recovery and transformation of the wastewater to bioenergy.
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- 2022
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6. Watermelon (Citrullus vulgaris) seed oil as a potential feedstock for biodiesel production in Nigeria
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O. C. Nwufo, G. C. Nzebuka, B. U. Okonkwo, O. O. Okorafor, C. C. Onwuachu, C. Ononogbo, and J. O. Igbokwe
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Renewable Energy, Sustainability and the Environment ,Waste Management and Disposal - Published
- 2023
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7. Automated and Intelligent Satellite Mission Operations Experiences with the N2 Satellite Ground Segment and Future Directions
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Sanusi, M., primary, Ndana, M. Ibrahim, additional, Jamilu, A., additional, brahim, S. Ramadan, additional, Ngozi, U. Okonkwo, additional, Musa, Z. Mohammed, additional, Fatima, M. Kawuyo, additional, Aisha, S. Onozare, additional, and Patrick, O., additional
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- 2023
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8. Usage of Maize Storage Technologies for Postharvest Loss Prevention in OkeOgun/Saki Area of Oyo State, Nigeria
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Adewale A. Afolabi, Egobude U. Okonkwo, Oluwabunmi M. Omotuyi, Olusola B. Benson, Temitope S. Taiwo, and Ajibade O. Ajayi
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Crop ,Agricultural science ,Descriptive statistics ,Bulk storage ,Silo ,Postharvest ,Development ,General Agricultural and Biological Sciences ,Grain storage ,Education ,Mathematics - Abstract
This study’s objective assessed the usage of traditional and improved maize storage technologies by farmers in Saki/Oke-Ogun area of Oyo State. The study was conducted from April-July, 2019; using a validated structured questionnaire for data collection. A multi-stage sampling technique was adopted to draw a sample of 191 maize farmers. Grain storage technologies usage frequency was measured on a four-point Likert-type numerical scale 4-1 as regularly, occasionally, seldom, and never respectively. Descriptive analysis of collected data revealed regular usage of both raffia woven basket (98.9%) and traditional crib (96.1%) by respondents. Sampled maize farmers overwhelmingly indicated non-usage of rhombus (98.0%) to store their produce; with a substantial number (88.2%) rarely using containers. Further analysis shows maize farmers used improved crib regularly (76.5%). Inert atmosphere silo (80.4%), conventional silo (76.5%), purdue improved crop storage (90.2%) and zerofly™ (65.4%) bags were never used to store maize by farmers. Chi-square ) analysis revealed significant (p≤0.05) associations between technology usage and socioeconomic characteristics of maize farmers. The cost and bulk storage nature of improved storage technology could be traced to its never used; while awareness is also very low on the use of those cost effective bagged technologies.This study’s objective assessed the usage of traditional and improved maize storage technologies by farmers in Saki/Oke-Ogun area of Oyo State. The study was conducted from April-July, 2019; using a validated structured questionnaire for data collection. A multi-stage sampling technique was adopted to draw a sample of 191 maize farmers. Grain storage technologies usage frequency was measured on a four-point Likert-type numerical scale 4-1 as regularly, occasionally, seldom, and never respectively. Descriptive analysis of collected data revealed regular usage of both raffia woven basket (98.9%) and traditional crib (96.1%) by respondents. Sampled maize farmers overwhelmingly indicated non-usage of rhombus (98.0%) to store their produce; with a substantial number (88.2%) rarely using containers. Further analysis shows maize farmers used improved crib regularly (76.5%). Inert atmosphere silo (80.4%), conventional silo (76.5%), purdue improved crop storage (90.2%) and zerofly™ (65.4%) bags were never used to store maize by farmers. Chi-square ) analysis revealed significant (p≤0.05) associations between technology usage and socioeconomic characteristics of maize farmers. The cost and bulk storage nature of improved storage technology could be traced to its never used; while awareness is also very low on the use of those cost effective bagged technologies.
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- 2021
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9. On The Closed Form Strategies of an Investor under the CEV and CIR Processes
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Edikan E. Akpanibah, Udeme O. Ini, Ben I. Oruh, Chidi U. Okonkwo, Everestus Eze, and Bright O. Osu
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Computer science ,Mathematical economics - Abstract
In this paper, the explicit solutions of the optimal investment plans of an investor with exponential utility function exhibiting constant absolute risk aversion (CARA) under constant elasticity of variance (CEV) and stochastic interest rate is studied. A portfolio comprising of a risk-free asset modelled by the Cox-Ingersoll-Ross (CIR) process and two risky assets modelled by the CEV process is considered, where the instantaneous volatilities of the two risky assets form a 2 x 2 matrix n = {np,q}2x2 such that nnT is positive definite. Using the power transformation and change of variable approach with asymptotic expansion technique, explicit solutions of the optimal investment plans are found. Moreover, numerical simulations are used to study the effects of the interest rate, elasticity parameter, correlation coefficient and the risk averse coefficient on the optimal investment plans.
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- 2021
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10. The co-movement of Bitcoin and some African currencies – A wavelet analysis
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Farid Chighoub, Bright O. Osu, Ben I. Oruh, and Chidi U. Okonkwo
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Wavelet coherence ,co-movement-noise ,wavelet analysis ,wavelet coherence ,exchange rate ,Noise ,Wavelet ,Market forces ,Economics ,Econometrics ,Volatility (finance) ,Hedge (finance) ,Continuous wavelet transform ,continuous wavelet transform - Abstract
This paper investigated the co-movement between the bitcoin (BTC) and the exchange rates of some African currencies to the USD (United States Dollars) using the continuous wavelet transform (CWT) and wavelet coherence (WTC). This was done for the noisy as well as the denoised series. The CWT for the noisy series suggests high volatility for those who hold the currencies for the short term and low volatility for those who hold the currencies for a long-term period. The CWT of the denoised series suggests that volatility at low frequency is driven by noise, while volatility at a higher frequency is driven by market forces. The wavelet coherence suggests that in the presence of noise, bitcoin will be a hedge for the currencies. However, in the absence of noise, bitcoin is a haven for the Egyptian EGP, followed by the Algerian DZD, then the Nigerian NGN, and may not be a haven for the South African ZAR.
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- 2021
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11. Wavelet Analysis of Stocks in the Nigerian Capital Market
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C. Chibuisi, C U Okonkwo, Bright O. Osu, and K Uchendu
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Discrete wavelet transform ,Wavelet ,Beverage industry ,Econometrics ,Stock market ,Business ,Volatility (finance) ,Capital market ,Continuous wavelet transform ,Stock (geology) - Abstract
In this paper, the relationship between some selected stocks in the Nigerian Capital Market was investigated using wavelet analysis. The selected stocks are Dangote Cement (Dans) representing the housing sector, Julius Berger (Jbger) representing the Construction industry, Nestle Nigerian Plc (Nese) representing the food and beverages sector and United Bank of Africa (Ubas) representing the banking sector. The goal is to find out how the different sector relate to each other, t also serve as a guide for investors in the Nigerian stock Market. The result shows that on low frequencies, the coherence between stocks are low but volatile. The cross wavelet showed that there is little or no covariability in the magnitude of the movement among the selected stocks but there are co-variability in the direction of the movement. The continuous wavelet transform (wavelet spectrum) shows that for all the stocks, there is high volatility at the low frequency scales and low volatility at high frequency scales. The discrete wavelet transform (DWT) suggests that in the absence of noise, Nese (representing the food and beverage industry is the most volatile stock.
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- 2019
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12. Welfare effects of natural resource privatization: a dynamic analysis
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Martin F. Quaas and Jennifer U. Okonkwo
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Economics and Econometrics ,Discounting ,Inequality ,media_common.quotation_subject ,Pareto principle ,Development ,Natural resource ,Common-pool resource ,Microeconomics ,Resource (project management) ,Distributive property ,Economics ,Welfare ,General Environmental Science ,media_common - Abstract
This paper sets up a dynamic model to study the distributive effects of privatizing an open access resource. We show that with or without discounting, privatization is not always Pareto improving. We further derive conditions under which the poor are made worse off when private use rights are equally distributed compared to a situation with open access resource. These conditions imply that privatization is Pareto improving if the natural resource is sufficiently productive, inequality in alternative private project opportunities is low, and if there is no discounting. In addition, we show that once reduction in income from resource harvesting during the transition to a new steady state is accounted for, privatization is desirable for the poor only for very productive natural resources and low discount rates.
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- 2019
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13. Importance Of Chemical Reactivity In Understanding Environmental Hazard
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Charles U. Okonkwo
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- 2020
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14. Reactor Design With Matlab In A Manufacturing Environment
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Charles U. Okonkwo
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- 2020
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15. The Role Of Process Safety Management In The Manufacturing Engineering Technology Curriculum
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Charles U. Okonkwo and Jerry Gintz
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- 2020
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16. Integrating Dfe As Core Course For Engineering Technology Programs
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Marcia DeMendonca and Charles U. Okonkwo
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- 2020
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17. Environmental Engineering Technology As An Area Of Emphasis In Manufacturing
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Charles U. Okonkwo
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- 2020
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18. Optimal Investment Strategy for Defined Contribution Pension Scheme under the Heston Volatility Model
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C. Chibuisi, Chidi U. Okonkwo, Bright O. Osu, and Silas A. Ihedioha
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Pension ,Matching (statistics) ,Stochastic volatility ,Investment strategy ,media_common.quotation_subject ,010102 general mathematics ,Mathematics::Optimization and Control ,Hamilton–Jacobi–Bellman equation ,01 natural sciences ,Interest rate ,Heston model ,010101 applied mathematics ,Computer Science::Systems and Control ,Econometrics ,Economics ,0101 mathematics ,Constant (mathematics) ,media_common - Abstract
In this paper, the optimal investment strategy for a defined contribution (DC) pension scheme was modeled with the assumption that the fund is invested partly in riskless assets and partly in risky assets. The market has a constant interest rate, a stochastic volatility that follows the Heston model, the salary is assumed constant over the entire career of the Pension Plan Participant (PPP) and the contribution is a constant proportion of the salary. The CRRA utility function was utilized to obtain a Hamilton-Jacobi-Bellman (HJB) equation. The resulting HJB equation was solved using the Prandtl Asymptotic Matching Method following the works in the literature.
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- 2018
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19. Detection of Brain Activation in Unresponsive Patients with Acute Brain Injury
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Kelly M Burger, Joshua U Okonkwo, J. Claassen, Angela Velazquez, Kevin Doyle, Benjamin Rohaut, David Roh, Adu Matory, Andrey Eliseyev, E. Sander Connolly, Sachin Agarwal, Caroline Couch, Murad Megjhani, Soojin Park, Jean-Rémi King, Columbia University [New York], Neuroimagerie cognitive - Psychologie cognitive expérimentale (UNICOG-U992), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National de la Recherche Scientifique (CNRS), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie (UPMC), Université Pierre et Marie Curie - Paris 6 (UPMC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Saclay (COmUE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-CHU Pitié-Salpêtrière [AP-HP], and Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)
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Adult ,Male ,Brain activation ,medicine.medical_specialty ,Support Vector Machine ,MEDLINE ,Glasgow Outcome Scale ,Unconsciousness ,Motor Activity ,030204 cardiovascular system & hematology ,Electroencephalography ,03 medical and health sciences ,Cognition ,0302 clinical medicine ,Physical medicine and rehabilitation ,Reference Values ,Humans ,Medicine ,Glasgow Coma Scale ,Prospective Studies ,030212 general & internal medicine ,Prospective cohort study ,ComputingMilieux_MISCELLANEOUS ,Aged ,Neurologic Examination ,medicine.diagnostic_test ,[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior ,business.industry ,[SCCO.NEUR]Cognitive science/Neuroscience ,fungi ,Motor commands ,Brain ,food and beverages ,[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences ,General Medicine ,Middle Aged ,Prognosis ,Beyond the Blue: What Fellows Are Reading in Other Journals ,Intensive Care Units ,Area Under Curve ,Brain Injuries ,Reference values ,Female ,business - Abstract
Brain activation in response to spoken motor commands can be detected by electroencephalography (EEG) in clinically unresponsive patients. The prevalence and prognostic importance of a dissociation between commanded motor behavior and brain activation in the first few days after brain injury are not well understood.We studied a prospective, consecutive series of patients in a single intensive care unit who had acute brain injury from a variety of causes and who were unresponsive to spoken commands, including some patients with the ability to localize painful stimuli or to fixate on or track visual stimuli. Machine learning was applied to EEG recordings to detect brain activation in response to commands that patients move their hands. The functional outcome at 12 months was determined with the Glasgow Outcome Scale-Extended (GOS-E; levels range from 1 to 8, with higher levels indicating better outcomes).A total of 16 of 104 unresponsive patients (15%) had brain activation detected by EEG at a median of 4 days after injury. The condition in 8 of these 16 patients (50%) and in 23 of 88 patients (26%) without brain activation improved such that they were able to follow commands before discharge. At 12 months, 7 of 16 patients (44%) with brain activation and 12 of 84 patients (14%) without brain activation had a GOS-E level of 4 or higher, denoting the ability to function independently for 8 hours (odds ratio, 4.6; 95% confidence interval, 1.2 to 17.1).A dissociation between the absence of behavioral responses to motor commands and the evidence of brain activation in response to these commands in EEG recordings was found in 15% of patients in a consecutive series of patients with acute brain injury. (Supported by the Dana Foundation and the James S. McDonnell Foundation.).
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- 2019
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20. Welfare effects of carbon taxation on South African households
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Jennifer U. Okonkwo
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Economics and Econometrics ,Carbon tax ,Almost ideal demand system ,Poverty ,business.industry ,020209 energy ,media_common.quotation_subject ,05 social sciences ,02 engineering and technology ,Agricultural economics ,Tax revenue ,General Energy ,Public transport ,0502 economics and business ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Revenue ,Deadweight loss ,050207 economics ,business ,Welfare ,media_common - Abstract
This paper evaluates the welfare impacts of carbon taxation on South African households. Using household survey data for the period 2009–2015, I estimate the Quadratic Almost Ideal Demand System (QUAIDS) model to obtain elasticities and use them to simulate consumer responses to price changes resulting from carbon taxation. Results show that an increase in electricity and public transport prices following a carbon tax policy is regressive while a price increase in motor fuel is progressive. In addition, when there is a simultaneous increase in the prices of energy goods, the poorest and middle income households disproportionately suffer a higher welfare loss compared to the richest households. I also show that income is important in determining whether rural households experience a higher or lower welfare loss than urban households. Furthermore, revenue recycling in terms of lump-sum transfers of the tax revenue to households below the national poverty lines and the bottom 40% would offset the welfare loss from a carbon tax policy in South Africa.
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- 2021
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21. Bloodless Management of Severe Obstetric Hemorrhage With Very Severe Anemia: A Case Report
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Marcus Inyama, Kenneth Ogar Inaku, Chinedu U. Okonkwo, Etetim E. J. Asuquo, Cajethan I. Emechebe, Joseph O. Enabulele, and Nathaniel I. Usoro
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Adult ,Fetus ,Resuscitation ,Blood transfusion ,Hysterectomy ,business.industry ,medicine.medical_treatment ,Glasgow Coma Scale ,Anemia ,General Medicine ,Pregnancy ,Erythropoietin ,Anesthesia ,medicine ,Humans ,Gestation ,Blood Transfusion ,Female ,Hemoglobin ,business ,Jehovah's Witnesses ,medicine.drug - Abstract
This case report describes bloodless management of a 32-year-old Jehovah's Witness who had severe obstetric hemorrhage at 23 weeks of gestation, spontaneously delivering twin fetuses. After resuscitation with crystalloids and colloids, the patient was still bleeding and hemoglobin fell to 3.3 g/dL. She had emergency hysterectomy. On postoperative day 1, her hemoglobin was 1.3 g/dL and Glasgow Coma Scale 6 of 15. Electrolyte derangement and fluid overload were detected and treated promptly. She regained consciousness and received intravenous iron and erythropoietin. She recovered fully without complications and without blood transfusion. Hemoglobin at discharge (postoperative day 18) was 6.9 and 12.5 g/dL 4 months later.
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- 2021
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22. Is the environmental Kuznets curve hypothesis a sound basis for environmental policy in Africa?
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Boqiang Lin, Jennifer U. Okonkwo, Oluwasola E. Omoju, Ebenezer Megbowon, and Ngozi M. Nwakeze
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Driving factors ,Cointegration ,Renewable Energy, Sustainability and the Environment ,Natural resource economics ,020209 energy ,Strategy and Management ,02 engineering and technology ,Building and Construction ,010501 environmental sciences ,01 natural sciences ,Industrial and Manufacturing Engineering ,Industrialisation ,Kuznets curve ,Economy ,Negative relationship ,Energy intensity ,Sustainability ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Population growth ,0105 earth and related environmental sciences ,General Environmental Science - Abstract
Achieving economic development and environmental sustainability simultaneously is one of the most important development challenges for Africa today. The relationship between economic growth and environmental sustainability is founded on the environmental Kuznets curve (EKC). This paper examines the validity of the hypothesis and the driving factors of carbon dioxide (CO2) emission in five African countries using the STIRPAT empirical model, panel cointegration and fully modified ordinary least squares. Unlike previous studies, economic development is disaggregated into agriculture and industrial economic development. The results show that there is no evidence of the validity of the hypothesis in Africa, regardless of whether economic development is driven by agriculture or industrialisation. Energy structure and energy intensity are the two major driving forces of CO2 emissions in Africa. Population growth and urbanisation have negative relationship with CO2 emissions. From our results, the EKC is not a sound basis for environmental policy in Africa; rather, environmental policy in Africa, specifically for CO2 emissions mitigation, should focus on encouraging energy efficiency, enhancing the use of clean energy, incorporating the impact of population growth and harnessing the positive impacts of urbanisation.
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- 2016
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23. Factors influencing renewable electricity consumption in China
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Oluwasola E. Omoju, Jennifer U. Okonkwo, and Boqiang Lin
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Consumption (economics) ,Renewable Energy, Sustainability and the Environment ,business.industry ,Natural resource economics ,020209 energy ,02 engineering and technology ,Energy consumption ,Renewable energy ,Microeconomics ,0202 electrical engineering, electronic engineering, information engineering ,Economics ,Electricity market ,Electricity ,Feed-in tariff ,business ,Energy source ,Electricity retailing - Abstract
Renewable energy is an important factor in achieving a low-carbon economic development path in China. This paper investigates the factors influencing renewable electricity consumption in China. Specifically, the factors that influence the share of renewable electricity in total electricity consumption in China is investigated using data from 1980 to 2011 and employing the Johansen cointegration technique and vector error correction model. The result of the analysis shows that there is a long run relationship between renewable electricity consumption and GDP per capita, trade openness, foreign direct investment, financial development and share of fossil fuel in energy consumption. Economic development and financial development promotes renewable electricity consumption while foreign direct investment, trade openness and the lobby of conventional energy sources undermine the share of renewables in total electricity consumption in China. While the effects of shocks to the other variables appear to die out over time, the “lobby effect” is persistent and explosive. The results also show that there is a uni-directional short run causality from financial development to renewable electricity consumption and from renewable electricity consumption to trade openness. The Chinese government should pursue policies that not only increase the amount of renewable electricity, but also increase the share of renewables in total electricity consumption.
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- 2016
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24. Association between physical activity level and blood pressure: varied and graded mediating effects of obesity indices in schoolchildren – CORRIGENDUM
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Fatai A. Maruf, Marufat O. Odetunde, and Prosper U. Okonkwo
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03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Pediatrics, Perinatology and Child Health ,General Medicine ,030204 cardiovascular system & hematology ,Cardiology and Cardiovascular Medicine - Published
- 2020
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25. Users versus Cloud Service Providers, on the Trust, Threats, Confidentiality and Reliability in Using Cloud Computing Services
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NGOZI U, OKONKWO, primary and A.AJIBOLA, DR. MRS, additional
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- 2020
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26. Public Awareness of Hepatitis B Virus Infection in Cross River State, Nigeria: A Population-Based Survey
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U, Okonkwo, A, Otu, S, Ameh, and H, Okpara
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Adult ,Health Knowledge, Attitudes, Practice ,Hepatitis B virus ,Cross-Sectional Studies ,Surveys and Questionnaires ,Humans ,Nigeria ,Hepatitis B - Abstract
Hepatitis B Virus (HBV) infection is a public health problem that is endemic in Nigeria. Cross River State, a tourist state, located in the coastal area of Nigeria has a relatively high prevalence rate. Insufficient knowledge and negative attitudes are barriers to effective control of infectious diseases.To determine the Knowledge, Attitude and Practice (KAP) of HBV amongst residents of Cross River State, Nigeria.This was a cross sectional descriptive study. A total of 1,620 healthy adults from the three senatorial districts in Cross River State participated in the study from March to September, 2015. KAP towards HBV was assessed using a structured pre-tested questionnaire. Categorical variables were described as frequencies and continuous variables as median and interquartile range. In the inferential analysis, Kruskal-Wallis test was used to determine the relationship between socio-demographic variables and median KAP scores. A p value0.05 was considered significant. All analyses were performed using Stata 12 statistical package.A total of 1,465 respondents completed the questionnaire correctly giving a response rate of 91%. The M: F ratio was 1:1.8. The median age was 38 years. Majority (61%) was married and 32% had formal education up to the tertiary level. Only 45% knew that HBV causes hepatitis. Knowledge of routes of transmission was50% for blood transfusion, sexual contact and sharps but48% for vertical transmission. Median and interquartile range of knowledge scores for the south, central and northern senatorial districts were 8 (2-14), 13 (5-17) and 14 (6-18) which varied significantly with age (p =0.027). The overall attitude and practice towards persons living with HBV was poor. There was good correlation between KAP scores (p0.05).Knowledge of hepatitis B is low among adults in Cross River State. This correlates with poor attitude and practice towards HBV. There is need to utilize health education strategies to improve awareness among the populace, if Nigeria is to meet the global target of elimination of viral hepatitis by 2030.
- Published
- 2018
27. Impact of industrialisation on CO 2 emissions in Nigeria
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Jennifer U. Okonkwo, Boqiang Lin, and Oluwasola E. Omoju
- Subjects
Kaya identity ,Sustainable development ,education.field_of_study ,Cointegration ,Renewable Energy, Sustainability and the Environment ,Natural resource economics ,Population ,Error correction model ,Industrialisation ,Greenhouse gas ,Development economics ,Per capita ,Economics ,education - Abstract
Developing countries, including Nigeria, aim to achieve industrialisation and sustainable development. However, there are few empirical studies that examined the impact of industrialisation-led economic transformation on carbon emissions in developing countries. This is the focus of this study. The paper investigates the impact of industrial value-added on CO2 emissions in Nigeria using the Kaya Identity framework and Augmented Dickey Fuller (ADF), Johansen׳s cointegration technique and vector error correction model (VECM). The data spans from 1980 to 2011. The result of the ADF test indicates that continual long term policies that exert permanent shocks on the variables are required to achieve economic development, industrialisation and CO2 reduction. The result of the analysis shows that industrial value-added has an inverse and significant relationship with CO2 emissions, which suggests that there is no evidence that industrialisation increases carbon emissions in Nigeria. GDP per capita and population has positive and significant impacts on CO2 emission. Energy intensity and carbon intensity has positive but very weak significant impact (at 10% level) on CO2 emission. The paper recommends that policy makers in Nigeria should pursue pragmatic industrialisation policies coupled with modest decarbonisation and energy-efficiency measures in order to ensure long term industrial, economic and sustainable development.
- Published
- 2015
- Full Text
- View/download PDF
28. Will disruptions in OPEC oil supply have permanent impact on the global oil market?
- Author
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Jennifer U. Okonkwo, Boqiang Lin, and Oluwasola E. Omoju
- Subjects
Renewable Energy, Sustainability and the Environment ,Structural break ,Stakeholder ,Cartel ,International economics ,Diversification (marketing strategy) ,chemistry.chemical_compound ,chemistry ,Economy ,Economics ,Petroleum ,Production (economics) ,Production quota ,Unit root - Abstract
OPEC has long been a major stakeholder and strong player in the global energy market, especially in the petroleum sub-sector. In recent time, however, there have been questions over the influence of OPEC in the sub-sector due to changing petroleum production landscape specifically as a result of the discovery of unconventional energy resources in North America and emergence of non-OPEC petroleum producing and exporting countries. This development could have significant effect on the global energy market and the macro-economy of OPEC member countries. The stationarity or otherwise of OPEC oil production/supply has important implications for determining whether fluctuations in OPEC market supply has temporary or permanent effect. Using the Zivot–Andrews structural break stationarity test and production data of OPEC member countries from 1980 to 2011, this paper investigates whether fluctuations in OPEC market supply has temporary or permanent effect. The empirical analysis shows that for only 5 OPEC members–Nigeria, Saudi Arabia, Ecuador, Kuwait and UAE—is the hypothesis of unit root rejected. This implies that for the five (5) OPEC members, the effects of shocks to oil production are not permanent and future pattern of oil production can be predicted following past trend. The practical implication of this finding is that OPEC production quota strategy may not have long-term impact on the global oil market. Thus, the cartel needs to improve oil production policy coordination among members and ensure strict adherence to production quota while also stressing the need for diversification in member countries.
- Published
- 2015
- Full Text
- View/download PDF
29. Biochemical Effects of N-Hexane and Chloroform Fractions of Ceiba pentandra Leaf Used in the Folkloric Treatment of Diabetes
- Author
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A. Abdullah, U. Okonkwo, H. Muhammad, and M. Busari
- Subjects
Hexane ,chemistry.chemical_compound ,Chloroform ,chemistry ,Traditional medicine ,Ceiba ,Diabetes mellitus ,Botany ,medicine ,General Medicine ,Biology ,medicine.disease ,biology.organism_classification - Published
- 2015
- Full Text
- View/download PDF
30. Sustainable PEPFAR Funded In Service HIV Training Delivery Models: A Training Impact Evaluation from Nigeria
- Author
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K. Nike, J. Apata, A. Ehoche, E.A.C. Onu, J. Egharevba, U. Okonkwo, T. Madubuko, A.E. Nwandu, D. Olutola, and J. Ilozumba
- Subjects
Service (business) ,Medical education ,business.industry ,Impact evaluation ,Human immunodeficiency virus (HIV) ,General Medicine ,Infectious and parasitic diseases ,RC109-216 ,medicine.disease_cause ,Training (civil) ,Environmental health ,Medicine ,Public aspects of medicine ,RA1-1270 ,business - Published
- 2017
31. THE PURSUIT OF HISTORICAL OBJECTIVITY IN THE CLAIM THAT THE JEWS KILLED JESUS CHRIST
- Author
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U U Okonkwo
- Subjects
General Arts and Humanities ,Philosophy ,media_common.quotation_subject ,Jesus christ ,General Social Sciences ,Theology ,Objectivity (philosophy) ,media_common - Published
- 2019
- Full Text
- View/download PDF
32. Comparative evaluation of four Nigeria-derived diatomaceous earths and a commercial DE Insecto® againstCallosobruchusmaculatusF. (Coleoptera:Bruchidae) on two varieties of stored cowpea in Nigeria
- Author
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Egobude U. Okonkwo
- Subjects
Geography ,Agronomy ,Agroforestry ,Comparative evaluation - Published
- 2016
- Full Text
- View/download PDF
33. Plant Materials Used for Controlling Insect Pests of Stored Products in Nigeria, Families Annonaceae, Piperaceae, and Rutaceae
- Author
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Ego U. Okonkwo
- Subjects
Pharmacology ,Integrated pest management ,Piper ,biology ,media_common.quotation_subject ,fungi ,food and beverages ,Insect ,Piperaceae ,biology.organism_classification ,Toxicology ,Biopesticide ,Rutaceae ,Complementary and alternative medicine ,Annonaceae ,Botany ,Citrus fruit ,media_common - Abstract
Plant material from the families Annonaceae, Piperaceae, and Rutaceae are used for the protection of stored products against insect pests in Nigeria. Following an outline of the different methods used for assessing insecticidal activity, 16 plants and plant products are alphabetically listed within families, summarizing the laboratory data currently available and, where possible, information on constituents and comparative studies with conventional synthetic insecticides. Of these families, only a few, all species in the genera Citrus, Dennettia, and Piper have been sufficiently tested in the laboratory to give an indication of their potential usefulness as stored-product protectants. More rigorous testing of these plant materials is required if the potential for botanical protectants is to be realized and the plant materials can be compared with recommended synthetic insecticide pyrethroids for repellency/antifeedant activity, contact adult mortality, and reduction in F1 production along with se...
- Published
- 2005
- Full Text
- View/download PDF
34. An effective solid waste management system in Awka, Anambra State, Nigeria: a proffered solution of a well-articulated plan of attributes
- Author
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A. U. Okonkwo
- Subjects
Solid waste management ,education.field_of_study ,Engineering ,Municipal solid waste ,Waste management ,business.industry ,Population ,Agency (sociology) ,Plan (drawing) ,education ,business ,Waste management system - Abstract
Awka, the capital of Anambra State of Nigeria is presently experiencing various forms of waste management problems and is more or less already in a state of visual devastation. Methods of solid waste management are grossly inadequate and this could be attributed to approaches, which are not all embracing. Solid waste management in Awka has experienced change from one management agency to another without yielding the desired results. The existing approaches have often treated solid waste disposal as independent from solid waste generation or density of the population generating the waste or the characteristics of the waste being generated. This paper is emphasizing that, for an effective waste management system; there should be a well-articulated plan of the various attributes of the system. The degree of effectiveness is measured by the volume of actually generated waste and the rate at which it is evacuated.
- Published
- 2014
- Full Text
- View/download PDF
35. BUDD CHIARI SYNDROME: AN UNEXPECTED DIAGNOSIS IN A GASTROENTEROLOGY PRACTICE IN CALABAR, NIGERIA.
- Author
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M., KOOFFREH-ADA, E., CHUKWUDIKE, G., KAJOGBOLA, F., EGHWUBARE, U., OKONKWO, and O., NGIM
- Subjects
BUDD-Chiari syndrome ,HEPATIC veins ,THROMBOSIS ,MAGNETIC resonance imaging ,LIVER transplantation - Abstract
Background: Vascular disorders of the liver are relatively rare in clinical practice. Budd Chiari syndrome (BCS) is a potentially life-threatening condition. It describes a group of disorders characterized by hepatic venous outflow obstruction at any level from the small hepatic veins up to the junction of the inferior vena cava and the right atrium. The prevalence of Budd Chiari Syndrome is greatly influenced by geographical differences. There is a dearth of data in Nigeria regarding this condition. Case report: We report the case of a thirty seven year-old woman presenting with an eight year history of recurrent abdominal swelling, jaundice and progressive weight loss. The patient was promptly screened for viral hepatitis B and C, which were both negative. The laboratory work-up revealed mild hepatic dysfunction and an abdominal ultrasound scan showed mild hepatomegaly and ascites. Abdominal Computed Tomography (CT) scan findings were consistent with Budd Chiari Syndrome, based on the findings of an extensive thrombus, involving the common iliac and hepatic veins, in addition, the inferior vena cava (IVC) and right atrium. Conclusion: This case report highlights the importance of the knowledge of Budd Chiari Syndrome and the diagnostic approach. This condition should be considered whenever investigating the aetiology of chronic or acute liver disease in Gastroenterology practice in Nigeria. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
36. The efficacy of four seed powders and the essential oils as protectants of cowpea and maize grains against infestation byCallosobruchus maculatus(Fabricus) (Coleoptera: Bruchidae) andSitophilus zeamais(Motschulsky) (Coleoptera: Curculionidae) in Nigeria
- Author
-
W. I. Okoye and E. U. Okonkwo
- Subjects
Xylopia aethiopica ,biology ,Weevil ,Sitophilus ,biology.organism_classification ,medicine.disease_cause ,law.invention ,Callosobruchus maculatus ,Horticulture ,law ,Insect Science ,Monodora myristica ,Infestation ,medicine ,Agronomy and Crop Science ,Piper guineense ,Essential oil - Abstract
Seed powders and the essential oils of Dennettia tripetela Baker F., Piper guineense Schum and Thonn, Mondora myristica (Gaerth) Dunal and Xylopia aethiopica Dunal A. Rich were evaluated for their effectiveness in protecting cowpea and maize grains during storage. D. tripetela powder mixed with maize grains, at 1.5 g per 25 g was significantly more effective (P < 0.05) than P. guineense, M. myristica and X. aethiopica in achieving 100% mortality of adults of Sitophilus zeamais in 24 h, and was also as effective as pirimiphosmethyl (10 ppm) in achieving 100% mortality of adult weevil in 24 h, 3 months after treatment at a dose of 3g per 25 g. There was no F1 emergence except in grains treated with M. myristica, X. aethiopica and the untreated controls. Essential oils of D. tripetela and P. guineense achieved 100% mortality of adults of Callosobruchus maculatus and Sitophilus zeamais in 24 h. Except in cowpea treated with X. aethiopica cowpea and maize grains treated with seed oils suppressed the e...
- Published
- 1996
- Full Text
- View/download PDF
37. Genome Wide Association Analysis of a Founder Population Identified TAF3 as a Gene for MCHC in Humans
- Author
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Massimo Mangino, Michael R. Green, Michela Traglia, Tim D. Spector, Giorgio Pistis, Daniel O. Hart, Clara Camaschella, Corrado Masciullo, Swee Lay Thein, Paolo Gasparini, Cinzia Sala, Nicole Soranzo, Nicola Pirastu, Shawntel U. Okonkwo, So-Youn Shin, Iwan Buetti, Daniela Toniolo, Roberto Massacane, Santhi K. Ganesh, Pistis, G, Okonkwo, Su, Traglia, Michela, Sala, C, Shin, Sy, Masciullo, C, Buetti, I, Massacane, R, Mangino, M, Thein, Sl, Spector, Td, Ganesh, S, Pirastu, Nicola, Gasparini, Paolo, Soranzo, N, Camaschella, C, Hart, D, Green, Mr, Toniolo, D., Traglia, M, Pirastu, N, Gasparini, P, Camaschella, Clara, and Clinical Genetics
- Subjects
Erythrocyte Indices ,Linkage disequilibrium ,Erythrocytes ,Red Cells ,Genome-wide association study ,Hereditary spherocytosis ,Cohort Studies ,Hemoglobins ,0302 clinical medicine ,Molecular Cell Biology ,Erythropoiesis ,Promoter Regions, Genetic ,Cytoskeleton ,Genetics ,0303 health sciences ,Multidisciplinary ,Mean corpuscular hemoglobin concentration ,medicine.diagnostic_test ,Reverse Transcriptase Polymerase Chain Reaction ,Anemia ,Hematology ,Founder Effect ,Cellular Structures ,Italy ,030220 oncology & carcinogenesis ,Medicine ,RNA Interference ,Protein Binding ,Research Article ,Chromatin Immunoprecipitation ,Science ,Locus (genetics) ,Biology ,genetics [Hemoglobins] ,Polymorphism, Single Nucleotide ,03 medical and health sciences ,SDG 3 - Good Health and Well-being ,Cell Line, Tumor ,medicine ,Genome-Wide Association Studies ,Animals ,Humans ,Gene ,Genetic Association Studies ,030304 developmental biology ,TATA-Binding Protein Associated Factors ,Spectrin ,Hemoglobins: genetics ,Human Genetics ,Actin cytoskeleton ,medicine.disease ,Hematopoiesis ,Gene Expression Regulation ,Genetics of Disease ,Transcription Factor TFIID ,K562 Cells ,Genome-Wide Association Study - Abstract
The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5-10% of the total observed variance is explained by the genetic loci found to date, suggesting that additional loci should be searched using approaches alternative to large meta analysis. GWAS (Genome Wide Association Study) for red blood cell traits in a founder population cohort from Northern Italy identified a new locus for mean corpuscular hemoglobin concentration (MCHC) in the TAF3 gene. The association was replicated in two cohorts (rs1887582, P = 4.25E-09). TAF3 encodes a transcription cofactor that participates in core promoter recognition complex, and is involved in zebrafish and mouse erythropoiesis. We show here that TAF3 is required for transcription of the SPTA1 gene, encoding alpha spectrin, one of the proteins that link the plasma membrane to the actin cytoskeleton. Mutations in SPTA1 are responsible for hereditary spherocytosis, a monogenic disorder of MCHC, as well as for the normal MCHC level. Based on our results, we propose that TAF3 is required for normal erythropoiesis in human and that it might have a role in controlling the ratio between hemoglobin (Hb) and cell volume and in the dynamics of RBC maturation in healthy individuals. Finally, TAF3 represents a potential candidate or a modifier gene for disorders of red cell membrane.
- Published
- 2013
38. Application of HACCP to post-harvest processing of African breadfruit Treculia africana Decne in Nigeria
- Author
-
Ozioma N. Ubani and Ego U. Okonkwo
- Subjects
biology ,business.industry ,Flesh ,biology.organism_classification ,Husk ,Poor quality ,Biotechnology ,Crop ,Fodder ,Treculia africana ,Critical control point ,Hazard analysis and critical control points ,General Agricultural and Biological Sciences ,business ,Mathematics - Abstract
African breadfruit Treculia africana Decne ‘ukwa’ in Igbo is an important food crop in Southern Nigeria. The seed has less fat (4 to 7%) than some other nuts and contains 19% protein similar to most pulses. The dehulled seeds are in the form in which the seeds are consumed as main dish or roasted as snack. The spongy pulp (deseeded flesh) is used as fodder while the seed hulls are used as feedstuff. Most of the women processors of African breadfruit seeds seem to be ignorant of the importance of good processing practices in value addition to their products. Poor quality products which attract low prices or outright rejection by consumers is a problem for the processors. Processing of the seeds need the application of Hazard Analysis Critical Control Point (HACCP) system for production of high quality and safe products along the value chain for the processors and consumers either manually or mechanically. This study determined the processing stages of African breadfruit seeds from June to November, 2009 and identified the hazards and critical control points in these stages. The results will be useful in recommendations to the processors concerning the need for high quality and safe products. Key words: Hazard analysis critical control point (HACCP), processing, African breadfruit, Nigeria.
- Published
- 2012
- Full Text
- View/download PDF
39. Early virologic responce to pegylated interferon in chronic Hepatitis B infection
- Author
-
Nimzing G. Ladep, AO Malu, U Okonkwo, RA Ugiagbe, and EN Okeke
- Subjects
Male ,Hepatitis B virus ,medicine.medical_specialty ,MEDLINE ,Interferon alpha-2 ,Antiviral Agents ,Polymerase Chain Reaction ,Gastroenterology ,Polyethylene Glycols ,Hepatitis B, Chronic ,Chronic hepatitis ,Pegylated interferon ,Internal medicine ,Humans ,Medicine ,medicine.diagnostic_test ,business.industry ,Interferon-alpha ,General Medicine ,Recombinant Proteins ,Treatment Outcome ,Liver biopsy ,Virologic response ,DNA, Viral ,Case note ,business ,medicine.drug - Abstract
BACKGROUND Early virologic response to pegylated interferon in the treatment of chronic hepatitis B infection is not frequently reported. METHOD The case notes of the patients was retrieved and relevant data extracted, literature review was done using Medline. RESULT A report of a case of early virologic response in a 62 year old man with chronic hepatitis B infection, receiving pegylated interferon is presented with a review of the relevant literature. He had HBV DNA level assessed by PCR and histology of liver biopsy specimen. CONCLUSION Clinicians should be on the lookout for early virologic response to pegylated interferon and the eventual outcome of such early response.
- Published
- 2010
- Full Text
- View/download PDF
40. Management of urban water for domestic and industrial uses and sustainability in Anambra State, Nigeria
- Author
-
A, C C Ezeabasili, primary, O, L Anike, additional, and A U, Okonkwo, additional
- Published
- 2014
- Full Text
- View/download PDF
41. B115 Effects of a Maternal Infant HIV Care Clinic for HIV-infected mothers and exposed infants on follow up postnatal HIV testing and care in Southeastern Nigeria
- Author
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A. Nwandu, I. Okafor, E. Justin, J. Ilozumba, U. Okonkwo, C. Ezeaku, C. Onuoha, J. Egharevba, O. Mbah, A. Osuji, and D. Watson
- Subjects
Pediatrics ,medicine.medical_specialty ,Retrospective review ,business.industry ,Obstetrics ,Human immunodeficiency virus (HIV) ,Hiv testing ,medicine.disease_cause ,Southeastern Nigeria ,Infectious Diseases ,Hiv infected ,Medicine ,Pharmacology (medical) ,business - Published
- 2013
- Full Text
- View/download PDF
42. Application of HACCP to post-harvest processing of African breadfruit Treculia africana Decne in Nigeria
- Author
-
U. Okonkwo, Ego, primary
- Published
- 2012
- Full Text
- View/download PDF
43. Luxury Fashion Branding : Trends, Tactics, Techniques
- Author
-
U. Okonkwo and U. Okonkwo
- Subjects
- Fashion merchandising, Brand name products, Luxuries--Marketing
- Abstract
This groundbreaking fashion branding and management text brings an analytical business dimension to the marketing and corporate techniques of the luxury fashion goods industry. It will make engaging reading for anyone who wishes to learn about the captivating business of turning functional products into objects of desire.
- Published
- 2007
44. Pathogenesis of infectious bursal disease in cyclophosphamide-treated chickens
- Author
-
C. B. O. Onwujiobi, CI Nwosuh, John Osita Arinze Okoye, P. U. Okonkwo, and A. S. Onuoha
- Subjects
Pathology ,medicine.medical_specialty ,animal structures ,Necrosis ,General Immunology and Microbiology ,Cyclophosphamide ,Broiler ,Spleen ,Biology ,medicine.disease ,Virology ,Virus ,Infectious bursal disease ,Pathogenesis ,medicine.anatomical_structure ,Food Animals ,embryonic structures ,medicine ,biology.protein ,Animal Science and Zoology ,medicine.symptom ,Antibody ,medicine.drug - Abstract
Summary Broiler chickens inoculated with cyctophosphamide showed atrophie bursae and severe immuno‐suppression. Infectious bursal disease virus (IBDV) inoculation of the birds at 5 weeks of age caused neither clinical signs nor gross lesions. IBDV was re‐isolated from some bursae samples. Cyclophosphamide non‐treated (CYNT) chickens inoculated with IBDV showed bursal enlargement followed by atrophy. Examination of sections of the organ showed severe lymphocytic necrosis and depletion. IBDV was re‐isolated from the bursa and spleen. The geometric mean titres of the IBDV serum neutralizing antibodies for infected cyclophosphamide treated (CYT) and CYNT chickens were 4.3 and 955.4, respectively. The above observations show that CYT chickens did not develop clinical IBD in the presence of infection and severe immunosuppres‐sion. They confirm the hypothesis that a healthy bursa is essential for the development of clinical IBD in chickens within the susceptible age range.
- Published
- 1992
45. The control ofCallosobruchus maculatus(F.) in stored cowpea with dried groundRicinus communis(L.) leaves in Nigeria
- Author
-
W. I. Okoye and E. U. Okonkwo
- Subjects
Callosobruchus maculatus ,Horticulture ,biology ,Insect Science ,Ricinus ,Euphorbiaceae ,General Earth and Planetary Sciences ,PEST analysis ,biology.organism_classification ,Agronomy and Crop Science ,General Environmental Science - Abstract
One to five grams of dry ground castor leaves, Ricinus communis mixed with 300 g cowpea seeds, achieved mortality up to 100% in 7 days. After 48 h only 20% mortality was recorded with 5 g. The grains were protected from damage for more than 3 months. However, little energy was involved in collecting, drying and grinding sufficient quantities of leaves required for the experiment.
- Published
- 1992
- Full Text
- View/download PDF
46. Serum Levels of Pro-inflammatory Cytokines in relationship to outcomes in Children with P. falciparum malaria, in Nnewi-South east Nigeria
- Author
-
John C Aneke, Christian Ejike Onah, K. U. Okonkwo, EO Ukaejiofor, EC Okocha, JC Ebenebe, and Nancy C Ibeh
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Monocyte ,Febrile illness ,medicine.disease ,Gastroenterology ,Proinflammatory cytokine ,Immune system ,Cytokine ,medicine.anatomical_structure ,Internal medicine ,parasitic diseases ,Immunology ,medicine ,South east ,Platelet ,business ,Malaria - Abstract
Background and Objective : In P. falciparum malaria (PFM) infestation there are marked changes in cytokine production as the body mounts an immune response to it. Hence we set out to study these changes. Methods : A total of 158 cases of PFM among children attending the paediatric unit of our hospital and 56 healthy controls were studied. Children with febrile illness were screened for malaria using 10% Giemsa stained blood smear. Patients with positive smears were recruited; co-infected patients – those infected by another organism in addition to plasmodium specie.- were excluded. Whole blood was collected, some into plain tubes for serum cytokine testing and some into EDTA bottles for complete blood count and parasite density (PD) determination. Controls with asymptomatic parasitaemia were excluded. Results : Using the World Health Organization criteria for defining severe malaria; we identified 15 cases of severe and 143 cases of uncomplicated PFM. Significantly elevated levels of interleukin-1 (IL-1), interleukin 6 (IL-6) and tumour necrosis factor alpha (TNF-α) were seen in the uncomplicated and severe forms of PFM. It was observed that the elevated cytokine values correlated with PD (in uncomplicated PFM but not in the severe forms). The difference between PD/absolute monocyte count (AMC) ratio was not significant (p=0.13); while PD/platelet count (PC) and PC/ AMC ratios were significant (p=0.01, and 0.03 respectively) when compared between uncomplicated and severe disease. Conclusion : Our data seems to suggest that subjects with an adequate immune response to the parasite density, in terms of pro-inflammatory cytokine levels, presented with uncomplicated disease; while those who have an inadequate response presented with severe disease. The ratios of (PD/PC) and (PC/AMC), in the positive and negative directions respectively, may be predictors of increased disease severity. These observations may have implications for predicting disease outcome and PFM therapy. Key Words : plasmodium falciparum malaria, pro-inflammatory cytokines, Parasite density/Platelet count ratio, Platelet count/Absolute monocyte
- Published
- 1970
- Full Text
- View/download PDF
47. Genome wide association analysis of a founder population identified TAF3 as a gene for MCHC in humans.
- Author
-
Giorgio Pistis, Shawntel U Okonkwo, Michela Traglia, Cinzia Sala, So-Youn Shin, Corrado Masciullo, Iwan Buetti, Roberto Massacane, Massimo Mangino, Swee-Lay Thein, Timothy D Spector, Santhi Ganesh, CHARGE Consortium Hematology Working, Nicola Pirastu, Paolo Gasparini, Nicole Soranzo, Clara Camaschella, Daniel Hart, Michael R Green, and Daniela Toniolo
- Subjects
Medicine ,Science - Abstract
The red blood cell related traits are highly heritable but their genetics are poorly defined. Only 5-10% of the total observed variance is explained by the genetic loci found to date, suggesting that additional loci should be searched using approaches alternative to large meta analysis. GWAS (Genome Wide Association Study) for red blood cell traits in a founder population cohort from Northern Italy identified a new locus for mean corpuscular hemoglobin concentration (MCHC) in the TAF3 gene. The association was replicated in two cohorts (rs1887582, P = 4.25E-09). TAF3 encodes a transcription cofactor that participates in core promoter recognition complex, and is involved in zebrafish and mouse erythropoiesis. We show here that TAF3 is required for transcription of the SPTA1 gene, encoding alpha spectrin, one of the proteins that link the plasma membrane to the actin cytoskeleton. Mutations in SPTA1 are responsible for hereditary spherocytosis, a monogenic disorder of MCHC, as well as for the normal MCHC level. Based on our results, we propose that TAF3 is required for normal erythropoiesis in human and that it might have a role in controlling the ratio between hemoglobin (Hb) and cell volume and in the dynamics of RBC maturation in healthy individuals. Finally, TAF3 represents a potential candidate or a modifier gene for disorders of red cell membrane.
- Published
- 2013
- Full Text
- View/download PDF
48. Prevalence of Hypertension and Associated Factors among Schoolteachers in Calabar, Nigeria: A Cross-Sectional Study.
- Author
-
Nwevo CO, Nkang J, Nwilegbara S, Okonkwo U, Otu A, and Ameh S
- Subjects
- Humans, Nigeria epidemiology, Female, Cross-Sectional Studies, Male, Adult, Prevalence, Middle Aged, Risk Factors, Surveys and Questionnaires, Age Factors, Hypertension epidemiology, School Teachers statistics & numerical data, Body Mass Index
- Abstract
Background: Africa has the highest prevalence of hypertension at 46%. Schoolteachers are vulnerable to hypertension due to work-related and general risk factors. Identifying these factors is key to providing interventions., Aim: This study aimed to determine the prevalence of hypertension and associated factors among schoolteachers in Calabar, Nigeria., Methods: This was a cross-sectional study of 427 randomly selected schoolteachers who were recruited through a multistage sampling technique. Questionnaires were self-administered, and blood pressure measurements were done. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 20. A binary logistic regression analysis was used to determine factors associated with hypertension at a 5% significance level., Results: The mean age of the participants was 38 ± 9 years, and 65% of them were females. The prevalence of hypertension was 32%. The adjusted model showed that age and body mass index (BMI) were significantly associated with hypertension. The teachers in the 30-39 (adjusted odds ratio [aOR] = 2.63, 95% confidence interval [CI]: 0.93-7.43, P = 0.07), 40-49 (aOR = 6.27, 95% CI: 2.08-18.91, P < 0.01), and ≥50 (aOR = 7.95, 95% CI: 2.24-28.20, P < 0.01) year age categories had increased odds of being hypertensive than those in the 20-29-year-old age group. Those who were overweight (aOR = 2.63, 95% CI: 1.52-4.57, P < 0.01) or obese (aOR = 2.15, 95% CI: 1.21-3.85, P = 0.01) had two-fold increased odds of having hypertension compared with those who had normal weight., Conclusions: Increasing age and BMI are risk factors for hypertension in this study. Health interventions should focus on weight control, especially among older teachers., (Copyright © 2024 Copyright: © 2024 Nigerian Journal of Clinical Practice.)
- Published
- 2024
- Full Text
- View/download PDF
49. Establishing a hepatitis care centre to promote integrated care and population-level liver cancer prevention in Nigeria: experiences and opportunities.
- Author
-
Otu A, Kooffreh-Ada M, Effa E, Ameh S, Okonkwo U, Udoh U, Akpan U, Itam-Eyo A, Chukwudike E, Akpet O, Essien O, Ikobah J, Ereh S, Onoyom E, and Walley J
- Subjects
- Humans, Nigeria epidemiology, Delivery of Health Care, Integrated, Hepatitis A, Liver Neoplasms epidemiology, Liver Neoplasms prevention & control
- Published
- 2022
- Full Text
- View/download PDF
50. Managerial competencies-A survey of healthcare managers in a tertiary hospital in Calabar, South-South Nigeria.
- Author
-
Okonkwo U, Ekpeyoung B, Ndep A, and Nja G
- Subjects
- Adult, Community Health Services, Cross-Sectional Studies, Delivery of Health Care, Female, Humans, Male, Middle Aged, Nigeria, Professional Competence statistics & numerical data, Quality of Health Care, Surveys and Questionnaires, Tertiary Care Centers, Total Quality Management, Young Adult, Health Facility Administrators, Health Services Administration standards, Knowledge Management, Leadership, Professional Competence standards
- Abstract
Background: Tertiary hospitals are specialized institutions that provide managed care for patients. It has been shown that the productivity of any organization/institution is as good as the performance of its managers., Aim: This study assessed the management knowledge of Healthcare Managers in a tertiary hospital in Calabar, Nigeria., Methodology: This was a descriptive cross-sectional study that employed a structured questionnaire (adapted from the Health Leadership Alliance competency directory). Data were analyzed using SPSS version 20., Results: A total of 266 managers were included in this studywith a M: F ratio of 1.3:1. The knowledge rating of role of non-clinical professionals, regulatory agency standards, preparation of business communication, change process management and policy formulation and analysis varied significantly among the three levels of management (p < 0.05). Less than 50% of operational and middle managers rated themselves as experts in all the competency domains while majority (80%) of strategic managers rated themselves as more than proficient in most of the competency items., Conclusion: There is inadequate managerial knowledge at all levels of management in a typical tertiary hospital in Nigeria with the potential to impact negatively on quality healthcare delivery., Competing Interests: None
- Published
- 2020
- Full Text
- View/download PDF
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