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2. Autoren

Author

P. Albers, R.P. Andrié, J. Angenendt, B. Appenrodt, A. Arkudas, H. Aubin, R. Autschbach, S. Baldus, J. Balzer, J. Baltzer, J. Behr, A. Behrens, Marcus Benz, M. Berger, F. Berr, S.C. Bischoff, A. Böhm, M. Böhm, D. Bokemeyer, F. Borowitzka, M. Brüwer, M. Buchfelder, A. Burk, K. Caca, S. Daum, C. Detter, H.-C. Diener, W. Domschke, K. Doppler, C.E. Elger, C. Ell, J. Ellinger, H.-J. Epple, B. Esser, Sebastian Ewen, C. Fibbe, S. Fichtner-Feigl, P. Fiegel, W. Fischbach, M. Fischereder, U.R. Fölsch, M. Forsting, N. Frey, S.M. Freys, M. Friedrich, T. Frieling, U. Frommberger, P. Frühmorgen, S. Geidel, C.-T. Germer, F.-D. Goebel, A. Goetzenich, K. Grabitz, M. Greetfeld, A. Groeneveld, P.K. Groha, F. Gundling, C.N. Gutt, T. Haak, U. Hartmann, H. Hauner, C. Hausteiner-Wiehle, P. Henningsen, B. Herpertz-Dahlmann, D. Heuß, P. Heußner, J. Hoffmann, U. Hohenfellner, R.E. Horch, M. Hüll, S. John, B. Jordan, C. Jurowich, A. Käberich, H. Katus, C. Keck, M. Kelm, K. Kiehne, Adrienne Kilian, I. Kindermann, A. Kleindienst, K. Klingel, Y. von Kodolitsch, H. Kölbl, S. Koletzko, O. Kollmar, S. Konstantinidis, H.J. Kramer, M.E. Kreis, B. Kroener-Herwig, C. Kurschat, F. Lammert, G. Lamprecht, J.M. Langosch, P. Layer, L. Leifeld, A. Lichtenberg, K. Lindner, A. Link, N. Lügering, Achim Lusch, T. Marth, U. Merle, F. Mellert, M. Meyer-Marcotty, G. Michels, J.M. Middeke, G. Möddel, J. Mössner, A. Müller, J.L. Müller, R.-U. Müller, S.C. Müller, S. Müller-Lissner, U. Müller-Werdan, M. Neubrand, C. Neuhof, K.G. Parhofer, E. Petri, T. Pfeiffer, Adrian Pilatz, C. Pizarro, T. Pohle, E. Polykandriotis, C. Probst, W. Rascher, B. Rauch, M. Reuss-Borst, C. Riedner, E. Rietschel, V. Röckelein, Ch. Rüster, M. Ruß, M. Sailer, W. Sandmann, T. Sauerbruch, B. Schaaf, C.A. Schaefer, N. Schahab, A. Schaper, J. Schetelig, M. Schmitz, H.-G. Schnürch, J. Schölmerich, Ulf Schönermarck, J.W. Schrickel, A. Schuchert, H. Schunkert, S.E. Segerer, N. Senninger, U. Seybold, B. Siegmund, D. Skowasch, C. Sommer, U. Spengler, M. Stahl, A. Stallmach, G. Stolpmann, W. Stremmel, U. Sure, F. Tacke, B.T. te Wildt, P. Trinkler, H. Tröger, M. Unnewehr, T. Vloet, U. Voderholzer, P.M. Vogt, W. von Scheidt, F. Wagenlehner, T. Wahlers, L.T. Weber, T. Wehrmann, B.T. Weis-Müller, K. Werdan, U. Wintergerst, T. Wittwer, Gunter Wolf, K. Wölfling, G. Wolkersdörfer, D. Ziegler, and S. Zierz

Published
2018
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6. Achalasie

Author

S. Katsoulis, H.-J. Meyer, and U.R. Fölsch

Subjects
business.industry, Medicine, business
Published
2015
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7. Functional anatomy of the papilla Vateri

Author

U.R. Fölsch, T. Bobka, Friedrich Paulsen, Michael Tsokos, and Bernhard Tillmann

Subjects
Pathology, medicine.medical_specialty, medicine.diagnostic_test, Bile duct, business.industry, Lumen (anatomy), Anatomy, Mucous gland, digestive system, digestive system diseases, Endoscopy, Major duodenal papilla, medicine.anatomical_structure, Biliary tract, Duodenum, medicine, Surgery, business, Ampulla
Abstract

Background: Problems with intubation of the ampulla Vateri during diagnostic and therapeutic endoscopic maneuvers are a well-known feature. The ampulla Vateri was analyzed three-dimensionally to determine whether these difficulties have a structural background. Methods: Thirty-five human greater duodenal papillae were examined by light and scanning electron microscopy as well as immunohistochemically. Results: Histologically, highly vascularized finger-like mucosal folds project far into the lumen of the ampulla Vateri. The excretory ducts of seromucous glands containing many lysozyme-secreting Paneth cells open close to the base of the mucosal folds. Scanning electron microscopy revealed large mucosal folds inside the ampulla that continued into the pancreatic and bile duct, comparable to valves arranged in a row. Conclusions: Mucosal folds form pocket-like valves in the lumen of the ampulla Vateri. They allow a unidirectional flow of secretions into the duodenum and prevent reflux from the duodenum into the ampulla Vateri. Subepithelial mucous gland secretions functionally clean the valvular crypts and protect the epithelium. The arrangement of pocket-like mucosal folds may explain endoscopic difficulties experienced when attempting to penetrate the papilla of Vater during endoscopic retrograde cholangiopancreaticographic procedures.

Published
2001
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8. Neue Therapieoption bei M. Crohn

Author

U.R. Fölsch and S. Nitschmann

Subjects
Nephrology, medicine.medical_specialty, business.industry, Crohn disease, Azathioprine, Hepatology, Gastroenterology, Infliximab, Antibodies monoclonal, Internal medicine, Internal Medicine, medicine, business, medicine.drug
Published
2010
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9. Band 15, Heft 4, Dezember 1999

Author

U. Zöllner, B. Gloor, Kilian Weigand, F. May, H.-J. Brambs, W. Arnold, Jens Werner, N. Schmitter, M.W. Büchler, T. Arendt, C.A. Müller, S. Schölzel, Waldemar Uhl, R. Roscher, T. Foitzik, I. Klempa, H. Treugut, C. Müller, Ernst Klar, U.R. Fölsch, and J. Horn

Subjects
Gastroenterology, Surgery
Published
1999
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10. Indikationen für die interventionelle Endoskopie bei akuter biliärer Pankreatitis

Author

U.R. Fölsch and T. Arendt

Subjects
medicine.medical_specialty, Endoscopic retrograde cholangiopancreatography, integumentary system, medicine.diagnostic_test, business.industry, Gastroenterology, medicine.disease, digestive system, digestive system diseases, Surgery, Major duodenal papilla, surgical procedures, operative, stomatognathic system, medicine, Acute pancreatitis, business
Abstract

SummaryGallstone migration through the papilla of Vater may cause acute pancreatitis. The role of endoscopic retrograde cholangiopancreatography (ERCP) with endoscopic sphincterotomy (ES)

Published
1999
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11. Inhalt Band 15, 1999

Author

Jens Werner, J. Horn, F. May, U.R. Fölsch, W. Arnold, T. Arendt, M.W. Büchler, S. Schölzel, Kilian Weigand, T. Foitzik, I. Klempa, H. Treugut, B. Gloor, H.-J. Brambs, C. Müller, Ernst Klar, R. Roscher, C.A. Müller, N. Schmitter, Waldemar Uhl, and U. Zöllner

Subjects
Gastroenterology, Surgery
Published
1999
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13. Importance of Intracellular S-Adenosylmethionine Decarboxylase Activity for the Regulation of Camostate-lnduced Pancreatic Polyamine Metabolism and Growth: In vivo Effect of Two Novel S-Adenosylmethionine Decarboxylase Inhibitors

Author

U.R. Fölsch, Chr. Löser, and T. Fitting

Subjects
Intracellular Fluid, Male, Adenosylmethionine Decarboxylase, Pancreatic disease, Gabexate, Amidines, Biology, Guanidines, Ornithine decarboxylase, Random Allocation, chemistry.chemical_compound, In vivo, Polyamines, medicine, Animals, Enzyme Inhibitors, Rats, Wistar, Pancreas, Deoxyadenosines, Gastroenterology, Esters, medicine.disease, Rats, Spermidine, medicine.anatomical_structure, Liver, chemistry, Biochemistry, Enzyme inhibitor, Indans, Putrescine, biology.protein, sense organs, Intracellular
Abstract

The present study was designed to investigate the inhibitory potency of the two novel S-adenosylmethionine decarboxylase (SAM-DC) inhibitors MDL 73811 and CGP 48664 on the camostate-induced pancreatic polyamine metabolism and especially intracellular spermidine accumulation as well as pancreatic growth in vivo. Male Wistar rats (180 g) were either treated with (1) the synthetic trypsin inhibitor camostate (200 mg/kg b.w. orally twice daily), (2) camostate+MDL 73811 (100 mg/kg b.w. i.p. twice daily), (3) camostate+CGP 48664 (5 mg/kg b.w. i.p. once daily) or (4) saline as controls. Animals (5-9 per group) were sacrificed after 1, 2 and 5 days of treatment. MDL 73811 caused a long-lasting (95%; p0.005) inhibition of SAM-DC followed by a significant (p0.005) increase in ornithine decarboxylase and putrescine, while spermine was decreased (p0.005). In contrast to MDL 73811, CGP 48664 had little effect in vivo. Despite potent inhibition of SAM-DC camostate-stimulated intracellular spermidine accumulation was not prevented by the simultaneous administration of MDL 73811. Consequently organ growth was not affected either. Since de novo synthesis of spermidine was effectively inhibited by MDL 73811, counterregulatory mechanisms (i.e. interconversion pathway, extracellular uptake) had to step in to maintain the intracellular balance of spermidine. The present data support the general concept of the importance of intracellular spermidine accumulation for the maintenance of pancreatic growth in vivo.

Published
1997
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14. Weekly High-Dose 5-Fluorouracil 24-Hour Infusion and Intermediate-Dose Folinic Acid Bolus in Metastatic Colorectal Cancer

Author

K.-H. Zurborn, V. Boehme, T. Arendt, C. Stoffregen, U.R. Fölsch, G. Lorenz, and A. Schmid

Subjects
Cancer Research, medicine.medical_specialty, business.industry, Colorectal cancer, Hematology, medicine.disease, Gastroenterology, Surgery, Folinic acid, Bolus (medicine), Oncology, Fluorouracil, Internal medicine, medicine, In patient, business, medicine.drug
Abstract

Background: Weekly high-dose 5-fluorouracil (5-FU; 24-hour infusion of 2.6 g/m2) and folinic acid (FA; 500 mg/m2as 1- or 2-hour infusion) proved to be effective in patients with metastatic

Published
1996
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15. Reports of Oncological Societies

Author

J.M. Debois, Siegfried Seeber, Hans-Joachim Meyer, A. Wilier, M. Rave-Fränk, A. Schmid, Axel-R. Hanauske, K. Bornemann, K. Böhning, Clemens F. Hess, Peter M. Schlag, V. Boehme, M. Korn, G. Lorenz, Lutz Edler, M. Panzer, D. Laurent, U.R. Fölsch, C. Stoffregen, Jörg Rüdiger Siewert, Ulrich Fink, Stephan C. Bischoff, O. Pradir, K.-H. Zurborn, Hansjochen Wilke, G. Käfer, Udo Vanhoefer, O. Selberg, T. Arendt, Michael Stahl, W. Queißer, U.R. Kleeberg, H. Renter, Ruediger Hehlmann, A. Weirnann, F.M. Haustrate, R. Raab, T.G Wendt, K.M. Stenson, Eckhart Dühmke, F. W. Eigler, Jan Hastka, Reiner Hartenstein, Martin Busch, J. Müller, E.E. Vokes, Heinz Schmidberger, T.P.U. Wustrow, and K. Ranft

Subjects
Cancer Research, medicine.medical_specialty, Oncology, business.industry, Family medicine, Alternative medicine, Medicine, Hematology, business
Published
1996
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16. Autorenverzeichnis

Author

Wolfgang Rascher, Johannes Atta, I.B. Autenrieth, Karsten Becker, Marcus Benz, Reinhard Berner, Konrad Bork, Hans-Dieter Carl, S. Castell, W. Enzensberger, Hans-Jörg Epple, Hubertus Feußner, P. Fiegel, Wolfgang Fischbach, U.R. Fölsch, Wolfgang Frank, K. Friese, Andrea Gingelmaier, Frank-Detlef Goebel, Ilse Grosch-Wörner, Gerhard Haidl, Michael Hammer, W. Handrick, Thomas Hauer, K. Hörmann, Thomas Hornung, Tomas Jelinek, Klaus Andreas Jendrissek, Karlheinz Kiehne, Matthias Klein, Christian Kneitz, Henrik Köhler, Lars Köhler, Sibylle Koletzko, Jens Gert Kuipers, Frank Lammert, B. Lembcke, R. Loddenkemper, J. Lorenz, T. Löscher, Gerd Lux, K. Magdorf, Thomas Meinertz, Volker Melichar, H.J. Meyer, Jacob Nattermann, T. Nicolai, Tim Niehues, Bernward Passlick, Eiko E. Petersen, Boris Pfaffenbach, Hans-Walter Pfister, Adrian Pilatz, Annette Pohl-Koppe, H. Prange, D. Reinhardt, Ernst Rietschel, Reinhard Roos, Markus Ruhnke, K.P. Schaal, Michael Schifferdecker, Stefan Schliep, Thomas Schneider, H. Scholz, Annemarie Schraml, V. Schuster, Tino F. Schwarz, Ulrich Seybold, G. Siemon, Ulrich Spengler, Michael Sticherling, Christian Stremmel, B.A. Stuck, Thomas M.K. Völkl, Florian E.M. Wagenlehner, Lutz Weber, Wolfgang Weidner, Thomas Weinke, M. Weiß, Uwe Wintergerst, Martin Zeitz, and Theodor Zimmermann

Published
2013
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18. Autorenverzeichnis

Author

W. Domschke, M. Berger, W. Hohenberger, T. Meinertz, C. Vogelmeier, T. Sauerbruch, H.J. Kramer, S.C. Müller, H. Serve, M.M. Weber, B. Göke, J.R. Kalden, B. Manger, W. Rascher, B. Appenrodt, J. Atta, C. Auernhammer, I.B. Autenrieth, W. Avenhaus, M. Backmund, C. Bausewein, J. Behr, A. Behrens, R. Berner, F. Berr, N. Blank, E. Blind, M. Bockhorn, D. Bokemeyer, M. Böhm, G. Bönner, G.D. Borasio, K. Bork, J. Braun, H.-P. Bruch, T.H. Brümmendorf, U. Brunnberg, M. Brüwer, M.W. Büchler, C. Detter, S. Diederich, C. Diehm, J. Distler, D. Domagk, T. Dörner, H.-G. Dörr, H. Dralle, M. Dreyling, I. Ehlebracht-König, C. Ell, W. Enzensberger, H.-J. Epple, M. Fassnacht, H. Feußner, P. Fiegel, C. Fisang, D. Filipas, W. Fischbach, C.H. Flamme, J. Floege, U.R. Fölsch, C. Fottner, W. Frank, N. Frey, K. Friese, A. Frilling, M. Fröhner, P. Frühmorgen, P.R. Galle, S. Geidel, E. Genth, A. Gingelmaier, F.-D. Goebel, N. Gökbuget, R. Göke, K. Grabitz, M. Grünke, S. Hahner, W. Handrick, C. Hasslacher, E. Heidbreder, W. Heindel, V. Heinemann, J. Heitmann, H.W. Heiß, H. Hof, L. Hering, E. Hiller, A. Hirner, W.-K. Hofmann, E. Holler, A.H. Hölscher, G. Holtmann, J. Hölzen, J. Honegger, S. Hörle, K. Hörmann, R. Hörmann, I. Hornke, R.M. Huber, J. Hübner, R. Hummel, S. Irmscher, T. Jelinek, S. Jonas, E. Jost, H.H. Jung, G.J. Kahaly, M. Karaus, S. Katsoulis, H. Katus, H.P. Kessler, K. Kiehne, W. Kiess, M. Kindermann, Y. von Kodolitsch, H. Köhler, L. Köhler, M. Köhler, E. Kohne, H.-J. Kolb, J. Köninger, K. Koop, R. Köster, I. Kötter, H.J.J. Kramer, B. Kremer, P. Kroll, J.G. Kuipers, F. Lammert, M. Langer, M. Laukötter, H. Lehnert, B. Lembcke, M.M. Lerch, S. Liebe, A. Lieber, R. Loddenkemper, M. Löhr, H.-M. Lorenz, J. Lorenz, T. Löscher, M. Luster, G. Lux, K. Mann, J. Mayerle, U. Merle, H.-J. Meyer, C. Möbius, M. Moehler, H. Mönnikes, J. Mössner, S.A. Müller, T.J. Musholt, J. Nattermann, M. Neubrand, P. Neuhaus, B. Neundörfer, T. Nicolai, J. Nolde, H. Olschewski, J. Ostermeyer, C. Ott, S. Pahernik, U. Pankratius, K.G. Parhofer, B. Passlick, O. Pech, B. Pfaffenbach, T. Pfeiffer, A. Pilatz, T. Pohle, A. Pohl-Koppe, Katharina A. Ponto, H. Prange, A. Pruß, J. Rädle, B. Rauch, F. Raue, C. Reichel, C. Reindl, C. Reißfelder, Dipl.-Phys. J. Rendl, E. Rietschel, E. Rijcken, R. Roos, G. Rudofsky†, W. Samtleben, W. Sandmann, G. Sauter, K.P. Schaal, J.R. Schaefer, U. Schäfer-Graf, W. Schepp, M. Schlemmer, S. Schliep, H. Schmidt, B. Schmied, W. Schmiegel, A. Schießl, A. Schmid, A. Schneider, T. Schneider, J. Schölmerich, H. Scholz, U. Schönermarck, J. Schopohl, H. Schrezenmeier, H. Schulze-Koops, D. Schuppan, V. Schuster, G. Schüßler, O. Schwandner, T.F. Schwarz, R. Secknus, N. Senninger, O. Sezer, B.R. Simmen, U. Spengler, U. Stabenow-Lohbauer, R. Stebler, D. Steven, M. Sticherling, U. Strauch, C. Stremmel, W. Stremmel, B.A. Stuck, H. Stürz, C. Taube, O. Thulesius, K. Thurau, J.W. Thüroff, C. Tomiak, W. Uhl, D. Vallböhmer, T. Vogel, P. von den Driesch, F.M.E. Wagenlehner, A. Wagner, U. Wagner, K. Weber, W. Weidner, T. Weinke, B.T. Weis-Müller, M. Weiß, S. Willems, U. Wintergerst, M. Wirth, G.W. Wolkersdörfer, and M. Zeitz

Published
2011
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20. Subject Index, Vol. 43, 1991

Author

Martin Bickel, B. Lembcke, Kaito Tsurumi, Thomas Scholl, Klaus Weidmann, W.S. Bennett, C. Subramony, Robert M. Levin, E. Siegel, Ahmet Bilgen, C.W. Ogle, Alan J. Wein, Hiroyuki Mibu, Andreas W. Herling, Hajime Fujimura, R. Ebert, Masakatsu Nozaki, Yang Zhao, Hans-J. Lang, L.A. Farias, U.R. Fölsch, Robert Rippel, W. Gatzemeier, Karl-H. Scheunemann, A.A. Mihas, C.H. Cho, Masayuki Niwa, Angel K. Markov, and W. Creutzfeldt

Subjects
Pharmacology, Index (economics), Statistics, Subject (documents), General Medicine, Mathematics
Published
1991
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21. Inhibition of Glycemic and Hormonal Responses after Repetitive Sucrose and Starch Loads by Different Doses of the α-Glucosidase Inhibitor Miglitol (BAY m 1099) in Man

Author

W. Creutzfeldt, W. Gatzemeier, U.R. Fölsch, B. Lembcke, E. Siegel, and R. Ebert

Subjects
Adult, Blood Glucose, Male, Sucrose, medicine.medical_specialty, 1-Deoxynojirimycin, medicine.medical_treatment, Gastric Inhibitory Polypeptide, 030204 cardiovascular system & hematology, 01 natural sciences, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Internal medicine, Dietary Carbohydrates, medicine, Humans, Insulin, Glycoside Hydrolase Inhibitors, Pancreatic hormone, Glycemic, Pharmacology, Glucosamine, biology, Miglitol, Starch, General Medicine, Carbohydrate, 3. Good health, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Endocrinology, chemistry, Tolerability, Enzyme inhibitor, biology.protein, Imino Pyranoses, medicine.drug
Abstract

In two randomized, placebo-controlled, double-blind studies, the efficacy, duration of action and tolerability of a single morning dose of 25, 50, and 100 mg miglitol (BAY m 1099), an absorbable inhibitor of intestinal alpha-glucosidases, were assessed after repetitive sucrose or maize-starch loads (50 g of carbohydrates in 400 ml of water each at 08.00, 12.00, and 17.00 h). With sucrose, miglitol reduced the postprandial rise in blood glucose, serum insulin and serum gastric inhibitory polypeptide concentrations at any dosage. This effect was dose-dependent and confined to the first carbohydrate load in the morning, thus indicating the duration of alpha-glucosidase inhibition of less than 4 h. Sucrose malabsorption, indicated by breath hydrogen responses, occurred dose-dependently with 50 and 100 mg, but not with 25 mg of miglitol. Similarly, symptoms of carbohydrate malabsorption were absent with 25 mg of the inhibitor and mild to moderate after 50 and 100 mg of miglitol. With starch as the substrate, BAY m 1099 led to a significant amelioration of glycemic and hormonal rises after the first meal, but not thereafter. A numerical dose dependency was recognized, but this was not significant at the 5% level. Symptoms of carbohydrate malabsorption were absent with 25 mg and negligible with 50 mg BAY m 1099, but occurred almost regularly with the 100-mg dose. Breath hydrogen concentrations increased gradually with the dose of miglitol administered. A single morning dose of 25-100 mg of miglitol thus may be useful for the control of postprandial hyperglycemia after breakfast. Due to the duration of action of less than 4 h, this substance should be given with the three main meals.

Published
1991
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22. Contents, Vol. 43, 1991

Author

Yang Zhao, W. Gatzemeier, Angel K. Markov, Klaus Weidmann, W.S. Bennett, Thomas Scholl, R. Ebert, Martin Bickel, C. Subramony, C.H. Cho, Karl-H. Scheunemann, C.W. Ogle, Kaito Tsurumi, L.A. Farias, W. Creutzfeldt, Ahmet Bilgen, Masayuki Niwa, U.R. Fölsch, Alan J. Wein, Robert Rippel, Masakatsu Nozaki, A.A. Mihas, Robert M. Levin, Hajime Fujimura, Andreas W. Herling, Hans-J. Lang, Hiroyuki Mibu, B. Lembcke, and E. Siegel

Subjects
Pharmacology, General Medicine
Published
1991
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23. Autorenverzeichnis

Author

V. Andresen, J. Angenendt, C. Anthoni, B. Appenrodt, M. Arbogast, G. Arco, J. Atta, M. Auer, C. Auernhammer, I.B. Autenrieth, W. Avenhaus, R. Bachem, M. Backmund, D. Bänsch, A. Ballauff, J. Baltzer, J. Barth, A. Batra, M.A. Bazarra-Castro, S. Beck, K. Becker, Karsten Becker, J. Behr, A. Behrens, O. Belyaev, Ch. Bender-Götze, J. Bengel, M. Benz, von Haunerschen, J. Berberich, M. Berger, R. Berner, F. Berr, null S.C., N. Blank, C. Bleh, Eberhard Blind, H.E. Blum, N. Bock, M. Bockhorn, J. Böhler, M. Böhm, D. Bokemeyer, G. Bönner, K. Bork, G. Born, Thomas Brandt, J. Braun, H.-P. Bruch, T.H. Brümmendorf, M. Brüwer, U. Brunnberg, M. Buchfelder, G. Buchkremer, M.W. Büchler, H.-D. Carl, S. Castell, C. Daniels, S. Daum, C. Detter, G. Deuschl, E. Dieckmann, S. Diederich, C. Diehm, T. Diemer, H.C. Diener, H. Diepolder, J. Distler, T. Dörner, null Prof. Dr., D. Domagk, W. Domschke, A. Dragu, H. Dralle, M. Dreyling, P. van, T. Dürk, D. Ebert, I. Ehlebracht-König, C.E. Elger, C. Ell, J. Ellinger, G. Emons, O. Engel, W. Enzensberger, H.-J. Epple, R. Erbel, M. Fassnacht, Hubertus Feußner, M. Fichter, P. Fiegel, D. Filipas, C. Fisang, M. Fisch, W. Fischbach, N. Fischer, M. Fischer, C.H. Flamme, K. Fleckenstein, J. Floege, G. Fluhr, U.R. Fölsch, M. Forsting, C. Fottner, W. Frank, N. Frey, H. Freyberger, K. Friese, A. Frilling, PD. Dr. habil, U. Frommberger, P. Frühmorgen, Johannes Fuss, R. Gätje, P.R. Galle, S. Geidel, H.-Ch. Geiß, Ekkehard Genth, J.M. Gilsbach, A. Gingelmaier, F.-D. Goebel, J. Göhl, N. Gökbuget, R. Gold, M.A. Gonzalez-Carmona, F. Gossé, K. Grabitz, M. Greetfeld, F.A. Gries, I. Grosch-Wörner, N. Grüner, M. Grünke, A. Grüters-Kieslich, V. Gülberg, T. Haak, R. Häfner, M. Härter, T. Hagenacker, S. Hahn, S. Hahner, G. Haidl, M. Hammer, F. Hammersen, W. Handrick, F. Hanisch, M.P. Hansen, Sara Hanke, J. Haschka, C. Hasslacher, Th. Hauer, A. Hauptmann, M. Heckmann, E. Heidbreder, U. Heim, W. Heindel, J. Heitmann, U. Hegenbart, W. Hermann, J.M. Herrmann, B. Herpertz-Dahlmann, B. Heßlinger, D. Heuß, P. Heußner, E. Hiller, A. Hirner, A.H. Hölscher, J. Hölzen, W.H. Hörl†, S. Hörle, H. Hof, W.-K. Hofmann, W. Hohenberger, U. Hohenfellner, E. Holler, G. Holtmann, J. Honegger, H.C. Hopf, R.E. Horch, I. Hornke, T. Hornung, R.M. Huber, A. Hueber, J. Hübner, R. Hummel, S. Irmscher, O.E. Janßen, T. Jelinek, K.A. Jendrissek, S. Jonas, E. Jost, H.H. Jung, G.J. Kahaly, J.R. Kalden, J. Kalff, T. Kapellen, M. Karaus, O. Kastrup, S. Katsoulis, H. Katus, C.P. Kaudel, R. Kaulitz, C. Keck, F. Keller, S. Kellnar, K. Kiehne, W. Kiess, M. Kindermann, A. Kirschbaum, M. Klein, A. Kleindienst, C. Kneitz, Y. von Kodolitsch, D. Köhler, H.P. Kessler, G. Köhler, H. Köhler, L. Köhler, M. Köhler, M. Köhnke, C. Königs, J. Köninger, D. Könsgen-Mustea, R. Köster, I. Kötter, E. Kohne, H.-J. Kolb, S. Koletzko, R. Kollmar, S. Konstantinidis, K. Koop, H.G. Kopp, T. Koschinsky, H.J. Kramer, J. Krauss, M.E. Kreis, B. Kremer, H.K. Kroemer, B. Kröner-Herwig, P. Kroll, A.K. Külz, H. Kuhl, J.G. Kuipers, M. Laaser, U. Lamla, F. Lammert, M. Langer, M. Laß, M. Laukötter, P. Layer, M. Leffler, H. Lehnert, M. Lehrke, B. Lembcke, M.M. Lerch, S. Liebe, A. Lieber, V. Limmroth, H. Lochs, R. Loddenkemper, J.-M. Löhr, T. Löscher, A. Loh, H.-M. Lorenz, J. Lorenz, N. Lügering, M. Luster, G. Lux, O. Luzar, A. Maercker, K. Magdorf, P. Mallmann, T. Marth, K. May, J. Mayerle, T. Meinertz, V. Melichar, U. Merle, H.J. Meyer, Th. Meyer, H. Meyer-Lehnert, A. Meyer-Marcotty, H. Michels, C. Möbius, G. Möddel, M. Möhler, H. Mönnikes, J. Mössner, M.G. Mohaupt, S.C. Müller, S.A. Müller, S. Müller-Lissner, J. Müller-Quernheim, A. Muntau, T.J. Musholt, W. Nacimiento, J. Nattermann, G. Nelles, M. Neubrand, C. Neuhäuser, P. Neuhaus, P.-A. Neumann, B. Neundörfer, T. Nicolai, W.-B. Niebling, T. Niehues, G. Nilius, J. Nolde, J. Noth, H. Olschewski, J. Ostermeyer, C. Ott, S. Pahernik, D. Palmes, U. Pankratius, K. Parhofer, R. Paschke, B. Passlick, O. Pech, F.W. Pelster, E.E. Petersen, E. Petri, B. Pfaffenbach, M. Pfeifer, T. Pfeiffer, H.W. Pfister, null Diplom-Gesundheitswirt, J. Pickel, A. Pilatz, M. Pirlich, E. Polykandriotis, B. Pontz, K. Possinger, A. Pohl-Koppe, T. Pohle, H. Prange, A. Prasse, A. Pruß, J. Rädle, K. Raile, W. Randerath, W. Rascher, B. Rauch, F. Raue, B. Raziorruh, J. Rech, A.C. Regierer, C. Reichel, C. Reindl, D. Reinhardt, C. Reißfelder, J. Rendl, M. Reuss-Borst, P. Rieckmann, C. Riedner, E. Rietschel, E. Rijcken, M. Rister, K. Rödder, S. Rogenhofer, F.C. Roos, R. Roos, D. Rosskopf, S. Rudnik-Schöneborn, G. Rudofsky†, M. Ruhnke, M. Ruß, C.F. Rust, F. Saborowski, M. Sailer, M. Sedigh Salakdeh, Walter Samtleben, W. Sandmann, T. Sauerbruch, K.P. Schaal, G. Schackert, U. Schäfer-Graf, M. Schäfers, A. Schalhorn, W. Schepp, J. Schetelig, M. Schifferdecker, J. Schipper, A. Schießl, U. Schlegel, S. Schliep, A. Schmid, P. Schmid, F. Schmidt, B. Schmied, W. Schmiegel, A. Schneider, T. Schneider, C. Schneider-Gold, H.-G. Schnürch, J. Schölmerich, U. Schönermarck, B. Schönhofer, S. Schönland, H. Scholz, J. Schopohl, G. Schott, J. Schrader, A. Schraml, H. Schrezenmeier, A. Schuchert, G. Schüßler, H. Schulze-Koops, D. Schuppan, V. Schuster, S. Schwab, O. Schwandner, C.H.M. Schwarz, T.F. Schwarz, K.W. Schweppe, R. Secknus, S.E. Segerer, N. Senninger, H. Serve, U. Seybold, O. Sezer, B. Siegmund, W. Siegmund, G. Siemon, B.R. Simmen, G. Simonetti, C. Sommer, U. Spengler, H. Sprott, U. Stabenow-Lohbauer, M. Stahl, G. Stalla, A. Stallmach, T. Stammschulte, R. Stebler, R. Stein, D. Steven, M. Sticherling, M. Stöhr, U. Strauch, A. Strauss, H.-G. Strauß, C. Stremmel, W. Stremmel, M. Strupp, E. Stüber, H. Stürz, U. Sure, B. Swoboda, C. Taube, K. Thiel, C. Thomssen, K. Thurau, J. Thöne, J. Thüroff, C. Tomiak, K.V. Toyka, H. Tröger, R.M. Trüeb, M. Tryba, W. Uhl, H. Ullerich, L. Unger, D. Vallböhmer, D. van Calker, T. Vloet, U. Voderholzer, Thomas M.K. Völkl, T. Vogel, P. Vogt, F.E.M. Wagenlehner, A. Wagner, U. Wagner, V. Wahn, C.W. Wallesch, F. Watzka, K. Weber, L. Weber, M.M. Weber, T. Wehrmann, W. Weidner, T. Weinke, M. Weiß, B.T. Weis-Müller, Michael Weller, F. Wenz, K. Werdan, M. Wettstein, M. Wick, I. Wiegratz, S. Willems, H. Wilke, U. Wintergerst, M. Wirth, G.W. Wolkersdörfer, C. Wüster, F. Zabel, H. Zeidler, M. Zeitz, K. Zerres, G. Ziemer, S. Zierz, T. Zimmermann, and J. Zwerina

Published
2007
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24. Pharmacological prevention of post-ERCP pancreatitis--an everlasting dream?

Author

U.R. Fölsch and S. Hellmig

Subjects
Cholangiopancreatography, Endoscopic Retrograde, medicine.medical_specialty, Serine Proteinase Inhibitors, Hepatology, Gabexate, business.industry, General surgery, medicine.medical_treatment, Cost-Benefit Analysis, Gastroenterology, medicine.disease, Major duodenal papilla, Catheter, Pancreatitis, Laparotomy, Medicine, Humans, business, Post ercp pancreatitis, Referral and Consultation, Hyperamylasemia
Abstract

In 1965 two radiologists, Rabinov and Simon [1], reported the first successful per oral cannulation of the papilla of Vater using a fluoroscopically guided catheter, rendering a non-operative pancreatography possible. At that time the surgical procedure of pancreatography was dangerous and difficult requiring not only a laparotomy but also duodenotomy and the radiological technique was clumsy, blind and time-consuming. Due to the improved flexibility of instruments, William S. McCune of George Washington University reported his experience with successful endos o t n a t t

Published
2006

25. Role of ERCP and endoscopic sphincterotomy in acute pancreatitis

Author

R. Nitsche and U.R. Fölsch

Subjects
medicine.medical_specialty, Pancreatic disease, Gastroenterology, Sensitivity and Specificity, Sphincterotomy, Endoscopic, Internal medicine, medicine, Humans, Randomized Controlled Trials as Topic, Cholangiopancreatography, Endoscopic Retrograde, Endoscopic retrograde cholangiopancreatography, medicine.diagnostic_test, business.industry, Bile duct, Gallstones, medicine.disease, Prognosis, Surgery, Endoscopy, Major duodenal papilla, medicine.anatomical_structure, Pancreatitis, Acute Disease, Acute pancreatitis, business
Abstract

When assessing the indications for interventional endoscopy, obstructive and non-obstructive causes of acute pancreatitis should be distinguished. In non-obstructive (e.g. alcoholic) pancreatitis, no data are available proving any benefit for endoscopic retrograde cholangiopancreatography (ERCP) and sphincterotomy. In obstructive (e.g. biliary) pancreatitis, the pathogenetic role of gallstones is controversial. The vast majority of gallstones initiating biliary pancreatitis pass spontaneously through the papilla of Vater into the duodenum without causing cholangitis or obstructive jaundice. Three prospective randomized published studies have attempted to answer the question of whether urgent removal of the stone improves the prognosis of patients suffering from acute pancreatitis. From these studies it can be concluded that the use of ERCP in acute biliary pancreatitis should depend on biliary symptoms: in cases of obstructive jaundice or cholangitis, bile duct stones should be removed as soon as possible; in patients without biliary complications, emergency ERCP is neither beneficial nor cost-effective; if retained stones (without biliary complications) are suspected, they can be removed electively.

Published
2000

26. Subject Index, Vol. 46, Supplement 2, 1990

Author

A. Stallmach, A. Pusztai, C. Susini, C. Bergs, T. Rokkas, Alison M. Buchan, V. Gant, Karen C. Watret, Celia Sharp, M. Delvaux, A.M.J. Buchan, G. Grant, Christoph Paprotny, M. Bensaïd, Gerburg Spiekermann, Hermon Dowling, P.K. Lund, Jens J. Holst, D. Felmelden, A.M. Stanier, A. Jarry, S. Vaja, Ernst-Otto Riecken, F. Alves, Claus Niederau, N. Brousse, G.M. Murphy, Nicholas A. Wright, M.R. Moffatt, Patricia Simon-Assmann, U. Braun, P.R. Taylor, M. Zeitz, R. Nustede, Linda D. Ferrell, T.T. MacDonald, C. Gespach, David H. Alpers, Per Brandtzaeg, Edward R. Seidel, R.D. Reidelberger, H. Köhler, S.P. James, Louis Buscail, H.P. Elsässer, G. Bornhoeft, R.C. Mason, S. Pignata, G. Tritto, V. Barbu, Rainer Nustede, D.S. Brown, R.-M. Liehr, L. D’Agostino, C.J. Bentzel, Annick Cauvin, S.W.B. Ewen, J.L. Allen, M.J. Bastie, Jean Christophe, H. Petersen, P. Simo, T.E. Solomon, H. Gregory, J. Chentoufi, Craig D. Logsdon, Philippe Gourlet, H.A. Jonas, Reinhard Lüthen, C. v. Hippel, C. Löser, J. Spencer, M. Fromm, F. Stöckmann, L. Pradayrol, R. Gentile, T.J. Palmer, J.L. Scemama, W Heise, R.A. Pederson, S. Emami, P. Taylor, David D. Ginty, Anton Schafmayer, F. Prats, M. Peiper, R.C. Macon, J.L. Taillemite, E. Chastre, H. Haarstad, K. Hinuma, S. Levin, E. J. M. Van Damme, M. Niederau, Roger Secknus, P. Sarfati, Michael Höcker, H.F. Kern, A.J. Cox, Tadataka Yamada, A. Contegiacomo, Ursula Hahn, Manfred L'age, Anjona Roy Choudhury, B. Göke, E. Douzinas, Jacques Abello, A.R. Bianco, C. Lavagna, S.B. Curtis, T.M. Taranto, C. Ferraro, E. Wehnes, F. Sandforth, Tadao Bamba, C. Seva, D.S. Louie, M.A. Ghatei, Robert T. Jensen, K.H. Herzig, J.P. Tauber, Clemens Sommer, G.A. Werther, Y Di Gioia, N. Tahiri-Jouti, H. Menge, F. Bouziges, Joachim Mössner, Daniel S. Longnecker, Lasse Raaberg, Rakesh Vinayek, Steven H. Erdman, Christian Löser, George Elia, S. Nizard, E. Riecken, M. Gregor, P. Rampal, Lars Thim, N. Cerf-Bensussan, Jerry D. Gardner, N. Vaysse, Toshiyuki Takeuchi, Lucio C. Rovati, M. Reinshagen, Knut Bjerke, Nikolaus Seiler, S.E. Hampson, Michèle Kedinger, M. Maghsoudloo, Dorothy B. Rountree, U.R. Fölsch, Roland Schwarting, Christine Pike, Ira Gantz, R.A. Goodlad, James H. Grendell, Andreas Schleser, O. Goulet, P.G. Isaacson, A. Garner, Catherine Damien, Georg Strohmeyer, I.R. Willshire, J.L. Nano, Michael Kruschwitz, S.R. Bloom, Henrik Harling, Rolf Nitsche, H.L. Schieferdecker, Ulrich R. Fölsch, S. Ito, Gabriele Fritzsche, W. Creutzfeldt, S. Rosewicz, I. McColl, L. Rubio, G. Mazzacca, Edward L. Stuenkel, G. Silvestro, Milton M. Weiser, John A. Williams, T. Takahashi, P Tagliaferri, C. Hanski, G.P. Young, C. Ricour, Katy Haffen, G. D’Adamo, Ernst Otto Riecken, Manabu Murakami, Y. Revillon, J.A. Young, Anne Ferguson, R.H. Dowling, Reiner Ullrich, B. Daniele, A.J. Madgwick, A. Schafmayer, James R. Wilson, Martin Zeitz, Stefan Rosewicz, K. Ziegler, U. Fölsch, Eric Vervisch, A. Hogg, Gerard M. Murphy, Patrick Robberecht, E.O. Riecken, H. Stein, N. Viguerie, W.J. Peumans, D. Guy-Grand, Steven E. Selub, L. De Vries, Werner Creutzfeldt, G. Adler, H. Dowling, I. Nevison, J. Domin, M.H. Lessof, A. Ribet, Wolfgang Schmidt, S. Bardocz, T.G. Nicolet, D. May, D. Schuppan, Harald Stein, J.D. Schulzke, T. N. Rasmussen, Michael N. Marsh, Martin H. Ulshen, Kay Lund, N.A. Wright, and C. Owyang

Subjects
Gerontology, Index (economics), Gastroenterology, Subject (documents), Psychology
Published
1990
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27. 900 CAVEOLIN-2 Q130E GENE POLYMORPHISM IS HIGHLY ASSOCIATED WITH RESPONSE TO ANTIVIRAL THERAPY IN HEPATITIS C AND CLINICAL FEATURES OF HEPATIC STEATOSIS

Author

Rainer Günther, H. Ulf, S. Roß, Samer Nasser, A. Ruether, I. Nitz, Diana Rubin, Stefan Schreiber, Peter Buggisch, F. Doering, J. Schrezenmeir, H. Vollbrecht, Holger Hinrichsen, U.R. Fölsch, and Michael Nothnagel

Subjects
Caveolin 2, Hepatology, business.industry, Antiviral therapy, medicine, Hepatitis C, Gene polymorphism, Steatosis, medicine.disease, business, Virology
Published
2009
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28. Subject Index Vol. 15, 1999

Author

Jens Werner, C. Müller, B. Gloor, N. Schmitter, Ernst Klar, H.-J. Brambs, R. Roscher, J. Horn, U. Zöllner, M.W. Büchler, T. Arendt, S. Schölzel, F. May, W. Arnold, H. Treugut, T. Foitzik, I. Klempa, Waldemar Uhl, U.R. Fölsch, Kilian Weigand, and C.A. Müller

Subjects
Index (economics), Statistics, Gastroenterology, Surgery, Subject (documents), Mathematics
Published
1999
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29. Autorenverzeichnis Band 15, 1999

Author

Kilian Weigand, T. Foitzik, I. Klempa, F. May, Jens Werner, B. Gloor, H.-J. Brambs, N. Schmitter, J. Horn, C.A. Müller, U.R. Fölsch, C. Müller, Waldemar Uhl, Ernst Klar, U. Zöllner, W. Arnold, T. Arendt, H. Treugut, M.W. Büchler, S. Schölzel, and R. Roscher

Subjects
Gastroenterology, Surgery
Published
1999
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30. Briefe an die Herausgeber

Author

W. Arnold, C. Müller, F. May, Ernst Klar, C.A. Müller, Kilian Weigand, R. Roscher, H. Treugut, M.W. Büchler, S. Schölzel, U. Zöllner, Waldemar Uhl, N. Schmitter, T. Foitzik, I. Klempa, T. Arendt, B. Gloor, H.-J. Brambs, J. Horn, U.R. Fölsch, and Jens Werner

Subjects
Gastroenterology, Surgery
Published
1999
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31. Sachwortverzeichnis Band 15, 1999

Author

C.A. Müller, F. May, N. Schmitter, C. Müller, Ernst Klar, U. Zöllner, J. Horn, Waldemar Uhl, W. Arnold, Kilian Weigand, Jens Werner, U.R. Fölsch, T. Arendt, M.W. Büchler, S. Schölzel, B. Gloor, T. Foitzik, H.-J. Brambs, I. Klempa, R. Roscher, and H. Treugut

Subjects
Gastroenterology, Surgery
Published
1999
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34. Regulation of Pancreatic Growth

Author

U.R. Fölsch

Subjects
medicine.medical_specialty, Endocrinology, business.industry, Internal medicine, Gastroenterology, Medicine, Bioinformatics, business
Published
1984
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35. Effect of a Soybean Diet on Enzyme Content and Ultrastructure of the Rat Exocrine Pancreas

Author

K. G. Wormsley, K. Winckler, and U.R. Fölsch

Subjects
endocrine system, medicine.medical_specialty, Normal diet, Secretin, Photometry, Internal medicine, medicine, Animals, Trypsin, Amylase, Lipase, Pancreas, Plant Proteins, biology, Kunitz STI protease inhibitor, fungi, Gastroenterology, food and beverages, Organ Size, Stimulation, Chemical, Diet, Rats, Microscopy, Electron, Endocrinology, medicine.anatomical_structure, Amylases, biology.protein, Ultrastructure, Soybeans, Cholecystokinin, Trypsin Inhibitors, medicine.drug
Abstract

The enzyme content and the ultrastructure of the rat exocrine pancreas were studied after feeding a normal diet or diets containing raw (RSF) or heat-inactivated (HSF) soybean flour for 20 days. The w

Published
1974
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36. THE POSSIBLE ROLE OF CYCLIC AMP AS A SECOND MESSENGER IN PANCREATIC DUCT CELLS

Author

U.R. Fölsch

Subjects
Pancreatic duct, 0303 health sciences, medicine.medical_specialty, Bicarbonate, chemistry.chemical_element, Radioimmunoassay, Calcium, 3. Good health, Secretin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, medicine.anatomical_structure, chemistry, Internal medicine, Second messenger system, medicine, 030211 gastroenterology & hepatology, Centrifugation, Incubation, 030304 developmental biology
Abstract

Publisher Summary This chapter examines the possible role of cyclic AMP (cAMP) as a second messenger in pancreatic duct cells. In a study described in the chapter, the pancreatic duct fragments were isolated by application of collagenase-induced dissociation of the lipomatotic tissue and different centrifugation steps. Between 10,000 and 16,000 fragments (each fragment consisted of 50 to 200 cells) per ml were used for all incubations with the hormones or choleratoxin. Concentrations of cAMP in the duct fragments were initially measured with a protein binding assay and subsequently with a radioimmunoassay. The fragments were incubated with the different agents at 37°C in Krebs–Ringer phosphate buffer (hormones) or Krebs–Ringer bicarbonate buffer (choleratoxin) containing 0.5 mM calcium and 1% albumin. The incubation time varied from 2 to 120 min dependent on the experimental setup. The respective time period of incubation is depicted. The results showed that with a maximal dose of secretin, cAMP concentration increased up to 10 min and then declined significantly to a lower plateau level. In combination with 5 × 10 −4 M theophylline, the concentration of cAMP continued to increase up to 20 min.

Published
1981
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37. To our Referees

Author

F. De Ritis, M.J. Turnbull, G. Wakisaka, R.H. Resnick, M. Fujii, Berard A, K. Winckler, Michael Hill, Harald Goebell, J.N. Badalamenti, F. De Marco, F.L. Iber, D.M. Shepherd, U.R. Fölsch, L. Jordö, Osvaldo Tiscornia, T. Scherstén, Henri Sarles, G. Budillon, Y. Matsumoto, K. Rommel, K. G. Wormsley, H. Minne, Monique Vagne, David Johnston, C. Lancaster, R. Ziegler, D. P. K. M. De Silva, H. Makopour, R. Olsson, S.P. de Silva, J.J. Cerda, J. Hotz, André Robert, Danielle Pansu, Gabriele Mazzacca, John G. Moore, J. Boitnott, Gilles Perret, Giuseppe Palasciano, T. Yamamoto, R. Morishita, M.A. Dechelette, R. Böhmer, R. Lambert, H. Ono, Martha Wolfe, James E. Nezamis, N. Nagaratnam, and B. Thjodleifsson

Subjects
Gastroenterology
Published
1972
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38. Putrescine transport in the rabbit small intestine mounted in the ussing chamber

Author

Dumontier, A.M., Brachet, Patrick, TOME, D., ProdInra, Migration, R.H. Dowling, U.R. Fölsch, C. Löser, Unité de nutrition humaine et de physiologie intestinale, and Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV] Life Sciences [q-bio], [SDV]Life Sciences [q-bio], ILEUM
Abstract

chap. 45

Published
1992

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