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10. An Exploration of Physical and Phenotypic Characteristics of Bangladeshi Children with Autism Spectrum Disorder

Author

Rahaman, Md. Ashiquir, Lopa, Maksuda, Uddin, K. M. Furkan, Baqui, Md. Abdul, Keya, Selina Parvin, Faruk, Md. Omar, Sarker, Shaoli, Basiruzzaman, Mohamm, Islam, Mazharul, AlBanna, Ammar, Jahan, Nargis, Chowdhury, M. A. K. Azad, Saha, Narayan, Hussain, Manzoor, Colombi, Costanza, O'Rielly, Darren, Woodbury-Smith, Marc, Ghaziuddin, Mohammad, Rahman, Mohammad Mizanur, and Uddin, Mohamm

Abstract

This study explored the physical and clinical phenotype of Bangladeshi children with autism spectrum disorder (ASD). A totally of 283 children who were referred for screening and administered Module 1 of the Autism Diagnostic Observation Schedule (ADOS) were included. Overall, 209 met the ADOS algorithmic cutoff for ASD. A trend for greater weight and head circumference was observed in children with ASD versus non-ASD. Head circumference was significantly (p < 0.03) larger in ASD males compared with non-ASD males. A trend was also observed for symptom severity, higher in females than males (p = 0.068), with further analyses demonstrating that social reciprocity (p < 0.014) and functional play (p < 0.03) were significantly more impaired in ASD females than males. The findings help understand sex differences in ASD.

Published
2021
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