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1. Impact of coronary revascularization on coronary flow capacity measured by transthoracic Doppler echocardiography in patients with chronic coronary syndrome

Author

Ueno, Hiroki, Usui, Eisuke, Hoshino, Masahiro, Kanaji, Yoshihisa, Sugiyama, Tomoyo, Hada, Masahiro, Nagamine, Tatsuhiro, Hanyu, Yoshihiro, Nogami, Kai, Setoguchi, Mirei, Sayama, Kodai, Tahara, Tomohiro, Matsuda, Kazuki, Sai, Rika, Sakamoto, Tatsuya, Shimosato, Hikaru, Watanabe, Takahiro, Mineo, Takashi, Yonetsu, Taishi, Sasano, Tetsuo, and Kakuta, Tsunekazu

Published
2024
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20. Prognostic Value of Integrated Assessment of Cardiac Magnetic Resonance-Derived Global Coronary Flow Reserve and Cardiopulmonary Exercise Testing-Derived Peak Oxygen Consumption in Patients With Acute Myocardial Infarction

Author

Sugiyama, Tomoyo, primary, Kanaji, Yoshihisa, additional, Hoshino, Masahiro, additional, Hada, Masahiro, additional, Hanyu, Yoshihiro, additional, Nagamine, Tatsuhiro, additional, Nogami, Kai, additional, Ueno, Hiroki, additional, Matsuda, Kazuki, additional, Sayama, Kodai, additional, Sakamoto, Tatsuya, additional, Usui, Eisuke, additional, Wakasa, Nobutaka, additional, Umino, Takashi, additional, Hamano, Ippei, additional, Yamamoto, Manabu, additional, Yonetsu, Taishi, additional, Sasano, Tetsuo, additional, and Kakuta, Tsunekazu, additional

Published
2024
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21. Characteristic findings of microvascular dysfunction on coronary computed tomography angiography in patients with intermediate coronary stenosis

Author

Hoshino, Masahiro, Yang, Seokhun, Sugiyama, Tomoyo, Zhang, Jinlong, Kanaji, Yoshihisa, Hamaya, Rikuta, Yamaguchi, Masao, Hada, Masahiro, Horie, Tomoki, Nogami, Kai, Ueno, Hiroki, Misawa, Toru, Yonetsu, Taishi, Hwang, Doyeon, Lee, Joo Myung, Shin, Eun-Seok, Doh, Joon-Hyung, Nam, Chang-Wook, Koo, Bon-Kwon, Sasano, Tetsuo, and Kakuta, Tsunekazu

Published
2021
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24. Utility of Magnetic Resonance Spectroscopy for the Progression of Neurological Symptoms in Lenticulostriate Artery Territory Infarction

Author

Shiga, Yuji, Nezu, Tomohisa, Nakamori, Masahiro, Hosomi, Naohisa, Akiyama, Yuji, Tachiyama, Keisuke, Kamimura, Teppei, Kinoshita, Naoto, Hayashi, Yuki, Matsushima, Hayato, Imamura, Eiji, Aoki, Shiro, Ueno, Hiroki, Ohshita, Tomohiko, Wakabayashi, Shinichi, Yamasaki, Fumiyuki, Awai, Kazuo, and Maruyama, Hirofumi

Published
2021
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27. A Mathematical Justification of a Thin Film Approximation for the Flow down an Inclined Plane

Author

Ueno, Hiroki and Iguchi, Tatsuo

Subjects
Mathematics - Analysis of PDEs
Abstract

We consider a two-dimensional motion of a thin film flowing down an inclined plane under the influence of the gravity and the surface tension. In order to investigate the stability of such flow, we often use a thin film approximation, which is an approximation obtained by the perturbation expansion with respect to the aspect ratio of the film. The famous example of the approximate equations are the Burgers equation, Kuramoto--Sivashinsky equation, KdV--Burgers equation, KdV--Kuramoto--Sivashinsky equation, and so on. In this paper, we give a mathematically rigorous justification of a thin film approximation by establishing an error estimate between the solution of the Navier--Stokes equations and those of approximate equations.

Published
2015

28. Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study

Author

Vita, Giuseppe, Rizzo, Vincenzo, Russo, Massimo, Mazzeo, Anna, Gentile, Luca, Berk, John L, Brueckner, Caitlin, Lazzari, Victoria, Wiesman, Janice, DeLong, Douglas, Victory, Jennifer, Dalton, James, May, John, Gilmore, Catherine, Attarian, Shahram, Diallo, Saran, Delmont, Emilien, Pouget, Jean, Verschueren, Annie, Grapperon, Aude-Marie, Campana-Salort, Emmanuelle, Conceição, Isabel M, Lopes, Ana, Lamas, Filipa, Neves, Carlos, Castro, Jose, Pereira, Pedro, Castro, Isabel, Franco, Ana, Santos, Miguel Oliveira, de Azevedo Coutinho, Conceição, Falcao de Campos, Catarina, Coelho, Teresa, Hipólito Reis, Antonio, Correia, Nuno, Perez, Javier M, Martins da Silva, Ana, Alves, Cristina, Cardoso, Marcio, Valdrez, Katia, Monte, Julia R, Pessoa, Bernardete, Guimaraes, Nadia, Freitas, Monica, Ramalho, Joana, Ferreira, Natalia, Kuzume, Daisuke, Tard, Celine, Waucquier, Nawal, Rougeaux, Isabelle, Brice, Sylvie, Kasprzyk, Emmanuelle, Elrezzi, Elise, Meguig, Sayah, Hachulla, Eric, Gauvain, Clement, Migaud-Chervy, Maria-Claire, Deplanque, Dominique, Jozefowicz, Elsa, Lebellec, Loic, Adams, David, Balaya-Gouraya, Line, Jehan Lacour, Nathalie, Bournane, Halima, Martin, Nathalie, Elabed, Mongia, Sacko, Niamey, Boubrit, Yasmine, Gaouar, Amina, Rakotondratafika, Fetra, Théaudin-Saliou, Marie, Cauquil-Michon, Cécile, Labeyrie, Celine, Not, Adeline, Al-Salameh, Abdallah, Lecoq, Anne-Lise, Stephant, Maeva, Echaniz-Laguna, Andoni, Becquemont, Laurent, Beaudonnet, Guillemette, Algalarrondo, Vincent, Eliahou, Ludivine, Slama, Michel S, Rousseau, Antoine, Signate, Aissatou, Berthelot, Emeline, Inamo, Jocelyn, Planté-Bordeneuve, Violaine, Vervoitte, Laetitia, Focseneanu, Cecile, Gendre, Thierry, Arrouasse, Raphaele, Ayache, Samar S., Ernande, Laura, Le Corvoisier, Philippe, Salhi, Hayet, Choumert, Ariane, Ehinger, Vincent, Ruiz, Julie, Charlin, Cyril, Megelin, Thomas, Brannagan III, Thomas H, Fayerman, Raisy, Kim, Arreum, Paras, Allan, Gonzalez, Leidy J, Tsang, Steven, Wajnsztajn, Fernanda, Shije, Jeffrey, Ulane, Christina, Kleyman, Inna, Weimer, Louis, Cioroiu, Comana, Lambrianides, Sakis, Abu-Manneh, Rana, Zamba-Papanicolaou, Eleni, Agathangelou, Petros, Leonidou, Eleni, Tada, Satoshi, Fujita, Akemi, Nagai, Masahiro, Ando, Rina, Hosokawa, Yuko, Yamanishi, Yuki, Overcash, J. Scott, Giardino, Elena, Boyer, Leslie, Dang, Lien, Le, An, Nguyen, Tyler, Giang, Lien, Sellers, Peter, Tran, Leyla, Truong, Nghi, Vinas, Maita, Hrkman, Nicole, Miller, Sarah, Nguyen, David, Smith, Ashley, Pu, Helen, Li, Steve, Vuong, Thao, Dioso, Holly, Green, Sinikka, Lee, Kia, Chu, Hanh, Waters, Michael, Coskun, Derya J, Zepeda, Karla A, O'Riordan, William, Obici, Laura, Cortese, Andrea, Lozza, Alessandro, Merlini, Giampaolo, Rosti, Vittorio, Sabatelli, Mario, Bisogni, Giulia, Bernardo, Daniela, Luigetti, Marco, Di Paolantonio, Andrea, Guglielmino, Valeria, Romano, Angela, Nienhuis, Hans, Bulthuis-Kuiper, Janita, Kristen, Arnt V, Gerk, Olga, Ulbricht, Hannah, Taylor, Lenka, Meyle, Eva, Kleinschmidt, Natalia, Meyrath, David, Noe-Schwenn, Simone, Meng, Ulrike, Bauer, Ralf, aus dem Siepen, Fabian, Hein, Selina, Takahashi, Tetsuya, Oshita, Tomohiko, Koujin, Yoko, Neshige, Shuichiro, Nezu, Tomohisa, Segawa, Akiko, Ueno, Hiroki, Morino, Hiroyuki, Campistol, Josep M, Rodas Marin, Lida Maria, Blasco Pelicano, Josep Miquel, Dávila, Lucía Galán, Palacios, Marta, Pytel Cordoba, Vanesa, Guerrero Sola, Antonio, Horga, Alejandro, García Feijoo, Julián, Perez de Isla, Leopoldo, Marques Júnior, Wilson, Moscardini, Mariana, Litcanov, Debora Cristina, Viera Lima, Ana Flavia, Rodrigues, Leonardo, Marques Coutinho, Barbara, Moreira, Carolina Lavigne, Daccach Marques, Vanessa, Munoz Beamud, Francisco, Gragera Martínez, Álvaro, Borrachero, Cristina, Losada López, Inés Asunción, Cisneros Barroso, Eugenia, Rodríguez Rodríguez, Adrián, Sanz, Monica, Rigo Oliver, Elena, González Moreno, Juan, Gamez Martinez, Jose M, Descals, Cristina, Uson, Mercedes, Jose Vega, Francisco, Figuerola, Antoni, Montala, Carles, Waddington-Cruz, Márcia, Dias da Silva, Moises, Gervais de Santa Rosa, Renata, Pinto, Luiz Felipe, Pinto, Marcus Vinicius, Cardoso Berensztejn, Amanda, Barroso, Fabio, Lautre, Andrea, Orellana, Lucas G, González-Duarte Briseño, Maria Alejandra, Cárdenas-Soto, Karla, Jiménez López, Brenda Poled, Pérez-Castañeda, Sandra Lorena, Cantú Brito, Carlos Gerardo, Rivera de la Parra, David, Hernandez Reyes, Jose Pablo, del Mar Saniger Alba, Maria, Criollo Mora, Elia, Parman, Yesim, Rezzan, Kus Jülide, Sahin, Erdi, Serbest, Nail G, Durmus, Hacer, Cakar, Arman, Tugal Tutkun, Nuriye Ilknur, Karamursel, Sacit, Elitok, Ali, Sirin Inan, Nermin G, Altinkurt, Emre, Polydefkis, Michael, Ye, Jing, Allen, Adriane C, Chaudhry, Vinay, Jarrett, Raquel, Bressler, Neil, Burks, Kathleen L, Liu, Qingfeng, Khoshnoodi, Mohammad, Judge, Daniel P, Vista, Geno, Shah, Syed Mahmood, Hamaguchi, Hirotoshi, Oda, Junko, Fukase, Emi, Taniguchi, Ikuko, Oda, Tetsuya, Endo, Hironobu, Shimomura, Masahiro, Katanazaka, Kimitaka, Koto, Shusuke, Nakano, Takahiro, Scheid, Christof, Zueiter, Andreas, Pester, Lars, Walter, Doreen, Özdemir, Betül, Frenzel, Lukas F, Holtick, Udo, Oh, Jeeyoung, Kim, Hee Jin, Shin, Hyun Jin, Choi, Kyomin, Yamashita, Taro, Ueda, Mitsuharu, Masuda, Teruaki, Misumi, Yohei, Ueda, Akihiko, Nakahara, Keiichi, Yorita, Akiko, Tsuruhisa, Seiko, Taniwaki, Takayuki, Harada, Masaya, Moritaka, Taiga, Sakurada, Naonori, Mauricio, Elizabeth A, Baskin, Amber, Dimberg, Elliot, Dispenzieri, Angela, Fonder, Amie, Hobbs, Miriam, Russell, Stephen J, Dyck, Peter, Gonsalves, Wilson, Leung, Nelson, Witzig, Thomas E, Zeldenrust, Steven R, Hwa, Lisa, Kapoor, Prashant, Kumar, Shaji K, Lin, Yi, Lust, John A, Rajkumar, Vincent S, Dingli, David, Gertz, Morie A, Go, Ronald, Hayman, Suzanne R, Dalia, Samir, Carrillo, Esmeralda, Gorevic, Peter, Mason, Garnette, Chao, Chi-Chao, Lee, Ming-Jen, Su, Jen-Jen, Hsieh, Sung-Tsang, Tsai, Li-Kai, Yeh, Shin-Joe, Yang, Chih-Chao, Ajroud-Driss, Senda Ajroud-Driss, Casey, Patricia, Joslin, Benjamin C, Freimer, Miriam, Sankey, Alison, Kenepp, Amanda, Heintzman, Sarah, LoRusso, Samantha, Hokezu, Youichi, Kim, Byoung-Joon, Kim, JuHyeon, Lee, Ga Yeon, Cho, Eun Bin, Jeon, Eun-Seok, Min, Ju-Hong, Seok, Jin Myoung, Lee, Hye Lim, Park, Jae Hong, Sekijima, Yoshiki, Miyazawa, Chinatsu, Kato, Nagaaki, Kishida, Dai, Hineno, Akiyo, Kodaira, Minori, Yoshinaga, Tsuneaki, Miyahara, Teruyoshi, Imai, Akira, Matsumoto, Kazuhiko, Lin, Kon-Ping, Lee, Yi-Chung, Wixner, Jonas, Falk, Malin, Pilebro, Bjorn, Suhr, Ole, Lindqvist, Per, Soderberg, Karin, Pedrosa-Domellöf, Fatima, Anan, Intissar, Nordh, Erik, Tournev, Ivaylo, Zhelyazkova-Glaveeva, Sashka, Cherneva, Zheyna, Sarafov, Staiko, Chamova, Teodora, Cherninkova-Gopina, Sylvia, Schmidt, Hartmut H, Friebel, Frauke, Zibert, Andree, Mihailovic, Natasa, Schubert, Friederike, Vorona, Elena, Lahme, Larissa, Huesing-Kabar, Anna, Schilling, Matthias, Kabar, Iyad, Gillmore, Julian D, Martinez-Naharro, Ana, Chacko, Liza, Cohen, Oliver, Law, Steven, Rezk, Tamer, Lachmann, Helen J, Quan, Dianna, Blume, Brianna, Dixon, Stacy, Low, Soon Chai, Chan, Soo Looi, Lim, He Eng Li, Goh, Khean Jin, Mezei, Michelle M, Kraus, Deborah, Jack, Kristin, Wade, N. Kevin, Lopate, Glenn, Zwijack, Brittany, Florence, Julaine, Sommerville, R. Brian, Stewart, Graeme, Ryder, Julie, Mekhael, Linda, Taylor, Mark, Suan, Daniel, Wells, Karen, Stone, Paula, Itoya, Amenze, Owusu-Sekyere, Mercy, Thai, Desmond, Chahine, Ilonah, Pedrosa, Salve, Do, Thi Hoa (Therese), González-Duarte, Alejandra, Kyriakides, Theodoros, Ajroud-Driss, Senda, Mauricio, Elizabeth, Brannagan, Thomas H, III, Aldinc, Emre, Wang, Jing Jing, White, Matthew T, Vest, John, Berber, Erhan, and Sweetser, Marianne T

Published
2021
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34. Uniform Estimates for the Flow of a Viscous Incompressible Fluid down an Inclined Plane in the Thin Film Regime

Author

Ueno, Hiroki, Shiraishi, Akinori, and Iguchi, Tatsuo

Subjects
Mathematics - Analysis of PDEs
Abstract

We consider a two-dimensional motion of a thin film flowing down an inclined plane under the influence of the gravity and the surface tension. In order to investigate the stability of such flow, it is hard to treat the Navier--Stokes equations directly, so that a thin film approximation is often used. It is an approximation obtained by the perturbation expansion with respect to the aspect ratio $\delta$ of the film under the thin film regime $\delta\ll1$. Our purpose is to give a mathematically rigorous justification of the thin film approximation by establishing an error estimate between the solution of the Navier--Stokes equations and those of approximate equations. To this end, in this paper we derive a uniform estimate for the solution of the Navier--Stokes equations with respect to $\delta$ under appropriate assumptions.

Published
2014

35. Impact of pericoronary adipose tissue inflammation on left ventricular hypertrophy and regional physiological indices in stable coronary artery disease patients with preserved systolic function

Author

Hirano, Hidenori, Kanaji, Yoshihisa, Sugiyama, Tomoyo, Hoshino, Masahiro, Horie, Tomoki, Misawa, Toru, Nogami, Kai, Ueno, Hiroki, Hada, Masahiro, Yamaguchi, Masao, Sumino, Yohei, Hamaya, Rikuta, Usui, Eisuke, Murai, Tadashi, Lee, Tetsumin, Yonetsu, Taishi, and Kakuta, Tsunekazu

Published
2021
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38. Association between optical coherence tomography-defined culprit morphologies and changes in hyperemic coronary flow after elective stenting assessed by transthoracic Doppler echocardiography.

Author

Usui, Eisuke, Hanyu, Yoshihiro, Sakamoto, Tatsuya, Hoshino, Masahiro, Hada, Masahiro, Nagamine, Tatsuhiro, Nogami, Kai, Ueno, Hiroki, Setoguchi, Mirei, Matsuda, Kazuki, Sayama, Kodai, Tahara, Tomohiro, Mineo, Takashi, Kanaji, Yoshihisa, Sugiyama, Tomoyo, Yonetsu, Taishi, Sasano, Tetsuo, and Kakuta, Tsunekazu

Subjects
DOPPLER echocardiography, PERCUTANEOUS coronary intervention, LOGISTIC regression analysis, COHERENCE (Optics), FLOW velocity, OPTICAL coherence tomography
Abstract

Background: Stress-transthoracic Doppler echocardiography (S-TDE) provides a noninvasive assessment of coronary flow parameters in the left anterior descending artery (LAD). However, the association between morphological characteristics and coronary flow changes after elective percutaneous coronary intervention (PCI) remains unclear. We aimed to evaluate the relationships between periprocedural coronary flow changes observed on S-TDE and lesion-specific plaque characteristics obtained by optical coherence tomography (OCT) in the interrogated vessels in patients with chronic coronary syndrome (CCS). Methods and results: Patients with CCS who underwent pre- and post-PCI S-TDE and elective fractional flow reserve (FFR)-guided PCI under OCT guidance for de novo single LAD lesions were included. S-TDE-derived hyperemic diastolic peak flow velocity (hDPV) was used as a surrogate for coronary flow. Lesions were categorized into two groups based on the %hDPV increase or decrease. The baseline clinical, physiological, and OCT findings were compared between the groups. In total, 103 LAD lesions were studied in 103 patients. After PCI, hDPV significantly increased from 55.6 cm/s to 69.5 cm/s (P<0.01), with a median %hDPV increase of 27.2 (6.32–59.1) %, while %hDPV decreased in 20 (19.4%) patients. The FFR improved in all patients. On OCT, layered plaques were more frequently present in the culprit vessels in the %hDPV-decrease group than in the %hDPV-increase group (85.0% vs. 50.6%, P = 0.01). Multivariable logistic regression analysis showed that the presence of layered plaques and high pre-PCI hDPV were independent predictors of %hDPV decrease. Conclusions: In patients who underwent successful uncomplicated elective PCI for de novo single LAD lesions, the presence of layered plaques was independently associated with hyperemic coronary flow decrease as assessed by S-TDE. [ABSTRACT FROM AUTHOR]

Published
2024
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39. Detection of unrecognized myocardial infarction by preprocedural transthoracic echocardiography in patients undergoing elective percutaneous coronary intervention

Author

Misawa, Toru, primary, Hoshino, Masahiro, additional, Sugiyama, Tomoyo, additional, Kanaji, Yoshihisa, additional, Hada, Masahiro, additional, Nagamine, Tatsuhiro, additional, Ueno, Hiroki, additional, Nogami, Kai, additional, Sayama, Kodai, additional, Matsuda, Kazuki, additional, Yonetsu, Taishi, additional, Sasano, Tetsuo, additional, and Kakuta, Tsunekazu, additional

Published
2023
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40. Diagnostic value of computed tomography myocardial perfusion imaging to detect coexisting microvascular dysfunction in patients with obstructive epicardial coronary artery disease

Author

Hada, Masahiro, primary, Hoshino, Masahiro, additional, Sugiyama, Tomoyo, additional, Kanaji, Yoshihisa, additional, Usui, Eisuke, additional, Hanyu, Yoshihiro, additional, Nagamine, Tatsuhiro, additional, Nogami, Kai, additional, Ueno, Hiroki, additional, Matsuda, Kazuki, additional, Sakamoto, Tatsuya, additional, Yonetsu, Taishi, additional, Sasano, Tetsuo, additional, and Kakuta, Tsunekazu, additional

Published
2023
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41. Prognostic implications of non-infarct-related territory unrecognized myocardial infarction in patients with non-ST-segment-elevation acute coronary syndrome

Author

Sayama, Kodai, primary, Hoshino, Masahiro, additional, Kanaji, Yoshihisa, additional, Sugiyama, Tomoyo, additional, Misawa, Toru, additional, Hada, Masahiro, additional, Nagamine, Tatsuhiro, additional, Nogami, Kai, additional, Teng, Yun, additional, Ueno, Hiroki, additional, Matsuda, Kazuki, additional, Yonetsu, Taishi, additional, and Kakuta, Tsunekazu, additional

Published
2023
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42. Prognostic Impact of Culprit Lesion Calcified Nodule After Emergency Coronary Intervention: A TACTICS Registry Subanalysis

Author

Hada, Masahiro, Kakuta, Tsunekazu, Sugiyama, Tomoyo, Hoshino, Masahiro, Yonetsu, Taishi, Usui, Eisuke, Hanyu, Yoshihiro, Nagamine, Tatsuhiro, Nogami, Kai, Ueno, Hiroki, Matsuda, Kazuki, Sayama, Kodai, Setoguchi, Mirei, Tahara, Tomohiro, Sakamoto, Tatsuya, Mineo, Takashi, Kobayashi, Nobuaki, Takano, Masamichi, Kondo, Seita, Wakabayashi, Kohei, Suwa, Satoru, Dohi, Tomotaka, Mori, Hiroyoshi, Kimura, Shigeki, Mitomo, Satoru, Nakamura, Sunao, Higuma, Takumi, Yamaguchi, Junichi, Natsumeda, Makoto, Ikari, Yuji, Yamashita, Jun, Mizukami, Takuya, Yamamoto, Myong Hwa, Sasano, Tetsuo, and Shinke, Toshiro

Published
2024
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45. Prognostic Implications of Fractional Flow Reserve and Coronary Flow Reserve After Drug-Eluting Stent Implantation

Author

Ueno, Hiroki, primary, Hoshino, Masahiro, additional, Usui, Eisuke, additional, Sugiyama, Tomoyo, additional, Kanaji, Yoshihisa, additional, Hada, Masahiro, additional, Misawa, Toru, additional, Nagamine, Tatsuhiro, additional, Hanyu, Yoshihiro, additional, Nogami, Kai, additional, Sayama, Kodai, additional, Matsuda, Kazuki, additional, Sakamoto, Tatsuya, additional, Yonetsu, Taishi, additional, Sasano, Tetsuo, additional, and Kakuta, Tsunekazu, additional

Published
2023
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46. LTE: Scientific basis for retraction of article “microvascular resistance reserve in the presence of functionally significant epicardial stenosis and changes after revascularization”

Author

Hanyu, Yoshihiro, primary, Hoshino, Masahiro, additional, Usui, Eisuke, additional, Sugiyama, Tomoyo, additional, Kanaji, Yoshihisa, additional, Hada, Masahiro, additional, Nagamine, Tatsuhiro, additional, Nogami, Kai, additional, Ueno, Hiroki, additional, Sayama, Kodai, additional, Matsuda, Kazuki, additional, Sakamoto, Tatsuya, additional, Yonetsu, Taishi, additional, Sasano, Tetsuo, additional, and Kakuta, Tsunekazu, additional

Published
2023
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48. Detection of unrecognized myocardial infarction by preprocedural transthoracic echocardiography in patients undergoing elective percutaneous coronary intervention.

Author

Misawa, Toru, Hoshino, Masahiro, Sugiyama, Tomoyo, Kanaji, Yoshihisa, Hada, Masahiro, Nagamine, Tatsuhiro, Ueno, Hiroki, Nogami, Kai, Sayama, Kodai, Matsuda, Kazuki, Yonetsu, Taishi, Sasano, Tetsuo, and Kakuta, Tsunekazu

Abstract

Background: Previous studies showed that unrecognized myocardial infarction (UMI) identified on cardiac magnetic resonance (CMR) was related to worse prognosis. We aimed to investigate the efficacy of preprocedural transthoracic echocardiography (TTE) to detect the presence of UMI in patients undergoing percutaneous coronary intervention (PCI). Methods: A total of 138 patients with chronic coronary syndrome (CCS) and preserved left ventricular ejection fraction (LVEF) without history of myocardial infarction or revascularization were retrospectively studied. UMI was evaluated with pre‐PCI late gadolinium enhancement (LGE)‐CMR. TTE and two‐dimensional speckle‐tracking echocardiography (2D‐STE) were performed before PCI. All patients were divided into two groups according to the presence or absence of UMI, and clinical and echocardiographic findings were compared between these two groups. Results: UMI was detected in 43 patients (31.2%). Multivariable logistic regression analysis revealed that higher SYNTAX score, the presence of wall motion abnormalities (WMAs) and lower global longitudinal strain (GLS) were independent predictors of the presence of UMI. Furthermore, GLS provided incremental efficacy for the detection of UMI over abnormal Q waves, SYNTAX score and WMAs. Conclusions: Preprocedural TTE in combination with 2D‐STE could help identify patients with UMI regardless of the presence or absence of ECG findings and WMAs. [ABSTRACT FROM AUTHOR]

Published
2024
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