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2. Principal component analysis of the Serological response to Plasmodium Falciparum using a Multiplex bead-based assay in Nigeria

Author

Schultz, Jonathan S., Okoli, Mary, Lee, Scott, Leonard, Colleen M., Sayre, Dean, Heilig, Charles M., Uhomoibhi, Perpetua, Ogunniyi, Abiodun, Ndodo, Nnaemeka, Mba, Nwando, Abubakar, Ado G., Akinmulero, Oluwaseun, Dawurung, Ayuba B., Okoye, McPaul, Iriemenam, Nnaemeka C., Plucinski, Mateusz, Steinhardt, Laura, Rogier, Eric, and Ihekweazu, Chickwe

Published
2024
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3. Correction: An observational analysis of the impact of deltamethrin + piperonyl butoxide insecticide-treated nets on malaria case incidence and entomological indicators in Ebonyi State, Nigeria, 2017–2021

Author

Davis, Kelly M., Okoko, Okefu O., Oduola, Adedayo O., Inyama, Petrus U., Uneke, Chigozi J., Ambrose, Kelley, Seyoum, Aklilu, Uhomoibhi, Perpetua, Rhoda, Dale A., Clary, Caitlin B., Millar, Justin, Littrell, Megan, Rogers, John H., Yoshimizu, Melissa, Inyang, Uwem, Maire, Mark, and Burnett, Sarah M.

Published
2024
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4. An observational analysis of the impact of deltamethrin + piperonyl butoxide insecticide-treated nets on malaria case incidence and entomological indicators in Ebonyi State, Nigeria, 2017–2021

Author

Davis, Kelly M., Okoko, Okefu O., Oduola, Adedayo O., Inyama, Petrus U., Uneke, Chigozi J., Ambrose, Kelley, Seyoum, Aklilu, Uhomoibhi, Perpetua, Rhoda, Dale A., Clary, Caitlin B., Millar, Justin, Littrell, Megan, Rogers, John H., Yoshimizu, Melissa, Inyang, Uwem, Maire, Mark, and Burnett, Sarah M.

Published
2024
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5. A qualitative look at bed net access and use in Burkina Faso, Mozambique, Nigeria, and Rwanda following piloted distributions of dual-active ingredient insecticide-treated nets

Author

Shannon, Jenny, Kagone, Moubassira, Candrinho, Baltazar, Otikwu, Sylvanus, Ingabire, Chantal, Gansane, Adama, Pooda, Samy, Aboubacar, Fofana, Ouattara, Fatou, Savaio, Binete, Joanguete, Celestino, Sixpence, Lucio, Koenker, Hannah, Uhomoibhi, Perpetua, Okoko, Okefu Oyale, Ali, Onoja, Babarinde, Dele, Ogundairo, Janet, Lemah, Ayorinde Samuel, Mbituyumuremyi, Aimable, Singirankabo, Joseph H., Kawakyu, Nami, Guglielmo, Federica, Fornadel, Christen, Arnett, Kyra, Wagman, Joe, Gogue, Christelle, Tynuv, Kenzie, Digre, Peder, Mwesigwa, Julia, and Robertson, Molly

Published
2024
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6. Assessing availability, prices, and market share of quality-assured malaria ACT and RDT in the private retail sector in Nigeria and Uganda

Author

Woldeghebriel, Meley, Aso, Ezinne, Berlin, Erica, Fashanu, Chizoba, Kirumira, Sylvia N., Lam, Felix, Mugerwa, Robert, Nakiganda, Juliet, Olaleye, Tayo, Opigo, Jimmy, Osinupebi, Funlola, Priestley, Natalie, Stringham, Rodger, Uhomoibhi, Perpetua, Visser, Theodoor, Ward, Abigail, Wiwa, Owens, and Woolsey, Aaron

Published
2024
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7. Spatial distribution and ecological niche modeling of geographical spread of Anopheles gambiae complex in Nigeria using real time data

Author

Adeogun, Adedapo, Babalola, Ayodele Samuel, Okoko, Okefu Oyale, Oyeniyi, Tolulope, Omotayo, Ahmed, Izekor, Romoke Tawakalitu, Adetunji, Oluwakemi, Olakiigbe, Abiodun, Olagundoye, Olalekan, Adeleke, Monsuru, Ojianwuna, Cynthia, Adamu, Dagona, Daskum, Abdullahi, Musa, Jibrin, Sambo, Obadiah, Adedayo, Oduola, Inyama, Petrus Uchenna, Samdi, Lazarus, Obembe, Abiodun, Dogara, Musa, Kennedy, Poloma, Mohammed, Suleiman, Samuel, Rebecca, Amajoh, Chioma, Adesola, Musa, Bala, Mohammed, Esema, Mary, Omo-Eboh, Mamudu, Sinka, Marianne, Idowu, Olufunmilayo Ajoke, Ande, Adeolu, Olayemi, Israel, Yayo, Abdulsalami, Uhomoibhi, Perpetua, Awolola, Samson, and Salako, Babatunde

Published
2023
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8. Using antenatal care as a platform for malaria surveillance data collection: study protocol

Author

Gutman, Julie R., Mwesigwa, Julia Nanteza, Arnett, Kyra, Kangale, Chabu, Aaron, Sijenunu, Babarinde, Dele, Buekens, Julie, Candrinho, Baltazar, Debe, Siaka, Digre, Peder, Drake, Mary, Gansané, Adama, Gogue, Christelle, Griffith, Kevin S., Hicks, Joseph, Kinda, Réné, Koenker, Hannah, Lemwayi, Ruth, Munsey, Anna, Obi, Emmanuel, Ogouyèmi-Hounto, Aurore, Okoko, Okefu Oyale, Onikpo, Faustin, Onoja, Ali, Porter, Travis, Savaio, Binete, Tynuv, Kenzie, Uhomoibhi, Perpetua, Wagman, Joseph, Wolf, Katherine, Zulliger, Rose, Walker, Patrick, Miller, John M., and Robertson, Molly

Published
2023
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15. Malaria Frontline Project: strategic approaches to improve malaria control program leveraging experiences from Kano and Zamfara States, Nigeria, 2016–2019

Author

Adewole, Adefisoye, Ajumobi, Olufemi, Waziri, Ndadilnasiya, Umar, Amina Abdullahi, Bala, Usaini, Gidado, Saheed, Ugbenyo, Gideon, Simple, Edwin, Igbaver, Isaac, Attahiru, Adam, Michael, Charles A., Uba, Belinda, Nguku, Patrick, Uhomoibhi, Perpetua, Muhammad, Basheer, Ismael, Munira, Cash, Shelby, Williamson, John, McElroy, Peter, Kachur, Stephen Patrick, and Asamoa, Kwame

Published
2023
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16. Design and methods for a quasi-experimental pilot study to evaluate the impact of dual active ingredient insecticide-treated nets on malaria burden in five regions in sub-Saharan Africa

Author

Gansané, Adama, Candrinho, Baltazar, Mbituyumuremyi, Aimable, Uhomoibhi, Perpetua, NFalé, Sagnon, Mohammed, Audu Bala, Guelbeogo, Wamdaogo Moussa, Sanou, Antoine, Kangoye, David, Debe, Siaka, Kagone, Moubassira, Hakizimana, Emmanuel, Uwimana, Aline, Tuyishime, Albert, Ingabire, Chantal M., Singirankabo, Joseph H., Koenker, Hannah, Marrenjo, Dulcisaria, Abilio, Ana Paula, Salvador, Crizologo, Savaio, Binete, Okoko, Okefu Oyale, Maikore, Ibrahim, Obi, Emmanuel, Awolola, Samson Taiwo, Adeogun, Adedapo, Babarinde, Dele, Ali, Onoja, Guglielmo, Federica, Yukich, Joshua, Scates, Sara, Sherrard-Smith, Ellie, Churcher, Thomas, Fornadel, Christen, Shannon, Jenny, Kawakyu, Nami, Beylerian, Emily, Digre, Peder, Tynuv, Kenzie, Gogue, Christelle, Mwesigwa, Julia, Wagman, Joseph, Adeleke, Monsuru, Adeolu, Ande Taiwo, and Robertson, Molly

Published
2022
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17. The potential public health consequences of COVID-19 on malaria in Africa

Author

Sherrard-Smith, Ellie, Hogan, Alexandra B., Hamlet, Arran, Watson, Oliver J., Whittaker, Charlie, Winskill, Peter, Ali, Fatima, Mohammad, Audu B., Uhomoibhi, Perpetua, Maikore, Ibrahim, Ogbulafor, Nnenna, Nikau, Jamilu, Kont, Mara D., Challenger, Joseph D., Verity, Robert, Lambert, Ben, Cairns, Matthew, Rao, Bhargavi, Baguelin, Marc, Whittles, Lilith K., Lees, John A., Bhatia, Sangeeta, Knock, Edward S., Okell, Lucy, Slater, Hannah C., Ghani, Azra C., Walker, Patrick G. T., Okoko, Okefu Oyale, and Churcher, Thomas S.

Published
2020
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19. Process and Methodological Considerations for Observational Analyses of Vector Control Interventions in Sub-Saharan Africa Using Routine Malaria Data

Author

Burnett, Sarah M., primary, Davis, Kelly M., additional, Assefa, Gudissa, additional, Gogue, Christelle, additional, Hinneh, Levi D., additional, Littrell, Megan, additional, Mwesigwa, Julia, additional, Okoko, Okefu O., additional, Rabeherisoa, Saraha, additional, Sillah-Kanu, Musa, additional, Sheahan, William, additional, Slater, Hannah C., additional, Uhomoibhi, Perpetua, additional, Yamba, Frederick, additional, Ambrose, Kelley, additional, and Stillman, Kathryn, additional

Published
2023
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23. Design, Implementation, and Coordination of Malaria Therapeutic Efficacy Studies in Nigeria in 2018

Author

Olukosi, Adeola Yetunde, primary, Musa, Adesola Zaidat, additional, Ogbulafor, Nnenna, additional, Aina, Oluwagbemiga, additional, Mokuolu, Olugbenga, additional, Oguche, Stephen, additional, Wammanda, Robinson, additional, Okafor, Henrietta, additional, Ekama, Sabdat Ozichu, additional, David, Agatha Nkiru, additional, Happi, Christian Tientcha, additional, Ozor, Lynda, additional, Babatunde, Seye, additional, Ijezie, Simon N., additional, Uhomoibhi, Perpetua E., additional, Awolola, Samson Taiwo, additional, Mohammed, Audu Bala, additional, and Salako, Babatunde Lawal, additional

Published
2023
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24. Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modeling analysis

Author

Runge, Manuela, primary, Stahlfeld, Anne, additional, Ambrose, Monique, additional, Toh, Kok Ben, additional, Rahman, Semiu, additional, Omoniwa, Omowunmi F., additional, Bever, Caitlin A., additional, Oresanya, Olusola, additional, Uhomoibhi, Perpetua, additional, Galatas, Beatriz, additional, Tibenderana, James K., additional, and Gerardin, Jaline, additional

Published
2023
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25. Additional file 1 of Facilitators and barriers to seasonal malaria chemoprevention (SMC) uptake in Nigeria: a qualitative approach

Author

Ogbulafor, Nnenna, Uhomoibhi, Perpetua, Shekarau, Emmanuel, Nikau, Jamilu, Okoronkwo, Chukwu, Fanou, Nadia M. L., Mbaye, Ibrahima Marietou, Ndiaye, Jean-Louis, Tchouatieu, Andre-Marie, Poku-Awuku, Abena, Merle, Corinne, Scott, Susana, Milligan, Paul, Ali, Aminu, Yusuf, Hauwa’u Evelyn, Oguche, Stephen, and Dahiru, Tukur

Abstract

Additional file 1. In Depth Interview Guide. This file contains the questions and prompts used by interviewers during data collection. The guide was developed based on a literature review and pilot testing.

Published
2023
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26. Additional file 1 of Application of mathematical modelling to inform national malaria intervention planning in Nigeria

Author

Ozodiegwu, Ifeoma D., Ambrose, Monique, Galatas, Beatriz, Runge, Manuela, Nandi, Aadrita, Okuneye, Kamaldeen, Dhanoa, Neena Parveen, Maikore, Ibrahim, Uhomoibhi, Perpetua, Bever, Caitlin, Noor, Abdisalan, and Gerardin, Jaline

Abstract

Additional file 1: Figure S1. Assignment of 774 LGAs in Nigeria into 22 epidemiological archetypes. Figure S2. Simulated seasonality of clinical malaria by archetype compared with the Rapid Impact Assessment health facility data for years 2014 – 2018. Thin red lines show 50 stochastic realizations and solid red dots and line show the mean over the realizations. Figure S3. a: Case management among children under the age, insecticide treated nets use and PfPR among children under the age of five years in 2010 by LGA. b: Two plots are shown for each archetype with archetype names at the top of each plot. The left plot is the larval habitat multiplierand likelihood evaluation against archetype U5 PfPR 2010 MIS. The red dot is maximum likelihood estimate of LHM. The right plot is the simulated U5 PfPR within each archetype compared with monthly U5 PfPR from the 2010 MIS. The thick red line indicates the best match while thin red lines show PfPR under other larval habitat scale factors. Each line is the mean of 10 stochastic realizations. 12 out of the 22 archetypes are shown here, remainder are shown in Fig S3b. Figure S4. ITN coverage among pregnant women attending ANC in 2018. Figure S5. Estimated ITN kill rate for a 12% reduction in annual malaria incidence among children under the age of five years. Figure S6. The relationship between permethrin bioassay mortality and ITN killing rate in the Churcher et al. model and EMOD. Scale factors was calculated by dividing the EMOD kill rateby the kill rate from the Churcher et al. model. Figure S7. Fitted splines showing estimated IPTp coverage through time for a random subset of LGAs. Points show DHS/MIS data and lines show the fitted splines, with each color indicating a different LGA. Figure S8. Fraction of IPTp-receiving individuals who reported receiving one, two, or three or more doses in each DHSor MIS. Figure S9. LGAs designated as eligible to receive IPTi. Figure S10. Mean DTP1-3 vaccine coverage per LGA in the 2018 DHS survey. Figure S11. Archetype level scatterplot highlighting beta-regression model equations used to compute predicted average yearly change CM coverages per archetype. Annual case management is the proportion of children with fever in the 2 weeks period prior to the survey that received an ACT. Figure S12. Malaria seasonality in routine health facility data and simulation for 37 Nigerian states in 2014. Incidence values in the health facility data were scaled by the median relative difference between the simulation and RIA data by state. Vertical purple horizontal lines are 95% confidence intervals for the RIA data. Vertical blue lines are the ranges of the simulations from 5 seed runs. Figure S13. Comparison of DHIS2 and simulation seasonality trends in 2014 with a cross-correlation function. CCF at the time lag zero is a measure of the contemporaneous correlation or the linear relationship between the two time series. Figure S14. Malaria seasonality in routine health facility data and simulation for 37 Nigerian states in 2015. Incidence values in the health facility data were scaled by the median relative difference between the simulation and RIA data by state. Vertical purple horizontal lines are 95% confidence intervals for the RIA data. Vertical blue lines are the ranges of the simulations from 5 seed runs. Figure S15. Comparison of DHIS2 and simulation seasonality trends in 2015 with a cross-correlation function. CCF at the time lag zero is a measure of the contemporaneous correlation or the linear relationship between the two time series. Figure S16. Malaria seasonality in routine health facility data and simulation for 37 Nigerian states in 2016. Incidence values in the health facility data were scaled by the median relative difference between the simulation and RIA data by state. Vertical purple horizontal lines are 95% confidence intervals for the RIA data. Vertical blue lines are the ranges of the simulations from 5 seed runs. Figure S17. Comparison of DHIS2 and simulation seasonality trends in 2016 with a cross-correlation function. CCF at the time lag zero is a measure of the contemporaneous correlation or the linear relationship between the two time series. Figure S18. Malaria seasonality in routine health facility data and simulation for 37 Nigerian states in 2017. Incidence values in the health facility data were scaled by the median relative difference between the simulation and RIA data by state. Vertical purple horizontal lines are 95% confidence intervals for the RIA data. Vertical blue lines are the ranges of the simulations from 5 seed runs. Figure S19. Comparison of DHIS2 and simulation seasonality trends in 2017 with a cross-correlation function. CCF at the time lag zero is a measure of the contemporaneous correlation or the linear relationship between the two time series. Figure S20. Malaria seasonality in routine health facility data and simulation for 37 Nigerian states in 2018. Incidence values in the health facility data were scaled by the median relative difference between the simulation and RIA data by state. Vertical purple horizontal lines are 95% confidence intervals for the RIA data. Vertical blue lines are the ranges of the simulations from 5 seed runs. Figure S21. Comparison of DHIS2 and simulation seasonality trends in 2018 with a cross-correlation function. CCF at the time lag zero is a measure of the contemporaneous correlation or the linear relationship between the two time series.

Published
2023
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27. Additional file 1 of Using antenatal care as a platform for malaria surveillance data collection: study protocol

Author

Gutman, Julie R., Mwesigwa, Julia Nanteza, Arnett, Kyra, Kangale, Chabu, Aaron, Sijenunu, Babarinde, Dele, Buekens, Julie, Candrinho, Baltazar, Debe, Siaka, Digre, Peder, Drake, Mary, Gansané, Adama, Gogue, Christelle, Griffith, Kevin S., Hicks, Joseph, Kinda, Réné, Koenker, Hannah, Lemwayi, Ruth, Munsey, Anna, Obi, Emmanuel, Ogouyèmi-Hounto, Aurore, Okoko, Okefu Oyale, Onikpo, Faustin, Onoja, Ali, Porter, Travis, Savaio, Binete, Tynuv, Kenzie, Uhomoibhi, Perpetua, Wagman, Joseph, Wolf, Katherine, Zulliger, Rose, Walker, Patrick, Miller, John M., and Robertson, Molly

Abstract

Additional file 1: ANC1 Surveillance Questions.

Published
2023
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28. Additional file 1 of Perennial malaria chemoprevention with and without malaria vaccination to reduce malaria burden in young children: a modelling analysis

Author

Runge, Manuela, Stahlfeld, Anne, Ambrose, Monique, Toh, Kok Ben, Rahman, Semiu, Omoniwa, Omowunmi F., Bever, Caitlin A., Oresanya, Olusola, Uhomoibhi, Perpetua, Galatas, Beatriz, Tibenderana, James K., and Gerardin, Jaline

Abstract

Additional file 1: Methodological supplement and additional results.

Published
2023
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29. Improving health information system for malaria program management: malaria frontline project lessons learned from Kano and Zamfara States, Nigeria, 2016-2019

Author

Adewole, Adefisoye, primary, Ajumobi, Olufemi, additional, Waziri, Ndadilnasiya, additional, Umar, Amina, additional, Bala, Usaini, additional, Gidado, Saheed, additional, Nguku, Patrick, additional, Uhomoibhi, Perpetua, additional, Muhammad, Basheer, additional, Ismail, Munira, additional, Cash, Shelby, additional, Williamson, John, additional, Kachur, Stephen Patrick, additional, McElroy, Peter, additional, and Asamoa, Kwame, additional

Published
2023
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30. Dynamics of IgG antibody response against Plasmodium antigens among Nigerian infants and young children.

Author

Leonard, Colleen M., Uhomoibhi, Perpetua, Abubakar, Ado, Ogunniyi, Abiodun, Mba, Nwando, Greby, Stacie M., Okoye, McPaul I., Iriemenam, Nnaemeka C., Ihekweazu, Chikwe, Steinhardt, Laura, and Rogier, Eric

Subjects
ANTIBODY formation, NIGERIANS, IMMUNOGLOBULIN G, ANTIGENS, CHILD mortality
Abstract

Background: Plasmodium falciparum malaria is a leading cause of child mortality in Nigeria. Neonates are born with maternal antibodies from placental transfer which may protect against malaria infection in the first months of life. The IgG dynamics of the transition from passively transferred antimalarial antibodies to actively acquired IgG from natural exposure have not been well elucidated. Methods: Blood samples collected during a 2018 Nigeria nationwide HIV/AIDS household survey were available for 9,443 children under 5 years of age, with a subset of infants under 2 months of age having maternal samples available (n=41). Samples were assayed for the P. falciparum HRP2 antigen and antimalarial IgG antibodies. LOESS regression examined the dynamics in IgG response in the first 5 years of life. Correlation with maternal IgG levels was assessed for mother/child pairs. Results: Consistent decreases were observed in median IgG levels against all Plasmodium spp. antigen targets for the first months of life. At a population level, P. falciparum apical membrane antigen-1 (AMA1) and merozoite surface protein- 1 19kD (PfMSP1) IgG decreased during the first 12 months of life before reaching a nadir, whereas IgGs to other targets only declined for the first 4 months of life. Seropositivity showed a similar decline with the lowest seropositivity against AMA1 and PfMSP1 at 10-12 months, though remaining above 50% during the first 2 years of life in higher transmission areas. No protective association was observed between IgG positivity and P. falciparum infection in infants. Maternal antibody levels showed a strong positive correlation with infant antibody levels for all P. falciparum antigens from birth to 2 months of age, but this correlation was lost by 6 months of age. Discussion: Maternally transferred anti-malarial IgG antibodies rapidly decline during the first 6 months of life, with variations among specific antigens and malaria transmission intensity. From 3-23 months of age, there was a wide range in IgG levels for the blood-stage antigens indicating high individual variation in antibody production as children are infected with malaria. Non-falciparum species-specific antigens showed similar patterns in waning immunity and correlation with paired mother's IgG levels compared to P. falciparum antigens. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Setting a Nigeria national malaria operational research agenda: the process

Author

Ajumobi, Olufemi, Uhomoibhi, Perpetua, Onyiah, Pamela, Babalola, Obafemi, Sharafadeen, Salami, Ughasoro, Maduka D., Adamu, Al-Mukhtar Y., Odeyinka, Oluwaseun, Orimogunje, Taiwo, Maikore, Ibrahim, Shekarau, Emmanuel, Ogunwale, Akintayo, Afolabi, Rotimi, Udeh, Sylvester, Ndubuisi, Akpuh, Umoette, Ntiense, Nguku, Patrick, and Ajayi, IkeOluwapo O.

Published
2018
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33. Malaria parasite density and detailed qualitative microscopy enhances large-scale profiling of infection endemicity in Nigeria

Author

Oyibo, Wellington, primary, Latham, Victoria, additional, Oladipo, Oladosu, additional, Ntadom, Godwin, additional, Uhomoibhi, Perpetua, additional, Ogbulafor, Nnnena, additional, Okoronkwo, Chukwu, additional, Okoh, Festus, additional, Mahmoud, Aminu, additional, Shekarau, Emmanuel, additional, Oresanya, Olusola, additional, Cherima, Yakubu Joel, additional, Jalingo, Innua, additional, Abba, Bintu, additional, Audu, Mohammed, additional, and Conway, David J., additional

Published
2022
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34. Facilitators and Barriers to SMC Uptake in Nigeria: A Qualitative Approach

Author

Ogbulafor, Nnenna, primary, Uhomoibhi, Perpetua, additional, Shekarau, Emmanuel, additional, Nikau, Jamilu, additional, Okoronkwo, Chukwu, additional, Fanou, Nadia ML, additional, MBaye, Ibrahima, additional, NDiaye, Jean Louis, additional, Tchouatieu, Andre-Marie, additional, Poku-Awuku, Abena, additional, Merle, Corinne, additional, Scott, Susana, additional, Milligan, Paul, additional, Ali, Aminu, additional, Yusuf, Hauwau, additional, Ogwuche, Stephen, additional, and Dahiru, Tukur, additional

Published
2022
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35. Drivers of long-lasting insecticide-treated net utilisation and parasitaemia among under-five children in 13 States with high malaria burden in Nigeria

Author

Uhomoibhi, Perpetua, primary, Okoronkwo, Chukwu, additional, Ajayi, IkeOluwapo O., additional, Mokuolu, Olugbenga, additional, Maikore, Ibrahim, additional, Fagbamigbe, Adeniyi, additional, Akinyemi, Joshua O., additional, Okoh, Festus, additional, Ademu, Cyril, additional, Kawu, Issa, additional, Kalambo, Jo-Angeline, additional, and Ssekitooleko, James, additional

Published
2022
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36. Introducing field digital data collection systems into seasonal malaria chemoprevention campaigns: opportunities for robust evidence development and national e-health strategies

Author

Balla, Kanda, primary, Malm, Kezia, additional, Njie, Ousman, additional, Hounto Ogouyemi, Aurore, additional, Uhomoibhi, Perpetua, additional, Poku-Awuku, Abena, additional, Tchouatieu, André-Marie, additional, Aikpon, Rock, additional, Bah, Alieu, additional, Kolley, Olimatou, additional, Ogbulafor, Nnenna, additional, Oppong, Samuel, additional, Adomako, Kofi, additional, Houndjo, William, additional, Jah, Huja, additional, Banerji, Jaya, additional, Nikau, Jamilu, additional, Affoukou, Cyriaque, additional, Egwu, Elijah, additional, Houtohossou, Camille, additional, and Van Hulle, Suzanne, additional

Published
2022
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37. Redoubling efforts to sustain seasonal malaria chemoprevention

Author

Uhomoibhi, Perpetua, primary, Malm, Keziah Laurencia, additional, Cisse, Idrissa, additional, Dzibo, Hamza, additional, Poku-Awuku, Abena, additional, Tchouatieu, André-Marie, additional, Olumese, Peter Ehizibue, additional, Van Hulle, Suzanne, additional, Florey, Lia, additional, Filler, Scott, additional, and Banerji, Jaya, additional

Published
2022
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38. Additional file 1 of Design and methods for a quasi-experimental pilot study to evaluate the impact of dual active ingredient insecticide-treated nets on malaria burden in five regions in sub-Saharan Africa

Author

Gansan��, Adama, Candrinho, Baltazar, Mbituyumuremyi, Aimable, Uhomoibhi, Perpetua, NFal��, Sagnon, Mohammed, Audu Bala, Guelbeogo, Wamdaogo Moussa, Sanou, Antoine, Kangoye, David, Debe, Siaka, Kagone, Moubassira, Hakizimana, Emmanuel, Uwimana, Aline, Tuyishime, Albert, Ingabire, Chantal M., Singirankabo, Joseph H., Koenker, Hannah, Marrenjo, Dulcisaria, Abilio, Ana Paula, Salvador, Crizologo, Savaio, Binete, Okoko, Okefu Oyale, Maikore, Ibrahim, Obi, Emmanuel, Awolola, Samson Taiwo, Adeogun, Adedapo, Babarinde, Dele, Ali, Onoja, Guglielmo, Federica, Yukich, Joshua, Scates, Sara, Sherrard-Smith, Ellie, Churcher, Thomas, Fornadel, Christen, Shannon, Jenny, Kawakyu, Nami, Beylerian, Emily, Digre, Peder, Tynuv, Kenzie, Gogue, Christelle, Mwesigwa, Julia, Wagman, Joseph, Adeleke, Monsuru, Adeolu, Ande Taiwo, and Robertson, Molly

Abstract

Additional file 1. Table S1. Summary of insecticide-treated bed net products.

Published
2022
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39. Additional file 2 of Design and methods for a quasi-experimental pilot study to evaluate the impact of dual active ingredient insecticide-treated nets on malaria burden in five regions in sub-Saharan Africa

Author

Gansan��, Adama, Candrinho, Baltazar, Mbituyumuremyi, Aimable, Uhomoibhi, Perpetua, NFal��, Sagnon, Mohammed, Audu Bala, Guelbeogo, Wamdaogo Moussa, Sanou, Antoine, Kangoye, David, Debe, Siaka, Kagone, Moubassira, Hakizimana, Emmanuel, Uwimana, Aline, Tuyishime, Albert, Ingabire, Chantal M., Singirankabo, Joseph H., Koenker, Hannah, Marrenjo, Dulcisaria, Abilio, Ana Paula, Salvador, Crizologo, Savaio, Binete, Okoko, Okefu Oyale, Maikore, Ibrahim, Obi, Emmanuel, Awolola, Samson Taiwo, Adeogun, Adedapo, Babarinde, Dele, Ali, Onoja, Guglielmo, Federica, Yukich, Joshua, Scates, Sara, Sherrard-Smith, Ellie, Churcher, Thomas, Fornadel, Christen, Shannon, Jenny, Kawakyu, Nami, Beylerian, Emily, Digre, Peder, Tynuv, Kenzie, Gogue, Christelle, Mwesigwa, Julia, Wagman, Joseph, Adeleke, Monsuru, Adeolu, Ande Taiwo, and Robertson, Molly

Abstract

Additional file 2. Annex S1. Country-specific context.

Published
2022
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40. The potential public health impact of COVID-19 on malaria in Africa

Author

Sherrard-Smith, Ellie, Hogan, Alexandra B., Hamlet, Arran, Watson, Oliver J., Whittaker, Charlie, Winskill, Peter, Ali, Fatima, Mohammad, Audu B., Uhomoibhi, Perpetua, Maikore, Ibrahim, Ogbulafor, Nnenna, Nikau, Jamilu, Kont, Mara D., Challenger, Joseph D., Verity, Robert, Lambert, Ben, Cairns, Matthew, Rao, Bhargavi, Baguelin, Marc, Whittles, Lilith K., Lees, John A., Bhatia, Sangeeta, Knock, Edward S., Okell, Lucy, Slater, Hannah C., Ghani, Azra C., Walker, Patrick G.T., Okoko, Okefu Oyale, and Churcher, Thomas S.

Subjects
Antimalarials, Betacoronavirus, Insecticides, Mosquito Control, SARS-CoV-2, Pneumonia, Viral, COVID-19, Humans, Public Health, Coronavirus Infections, Pandemics, Article, Malaria
Abstract

Malaria burden is heavily concentrated in sub-Saharan Africa (SSA) where cases and deaths associated with COVID-19 are rising. In response, countries are implementing societal measures aimed at curtailing transmission. Despite this, the COVID-19 epidemic could still result in millions of deaths as local health facilities become overwhelmed. Advances in malaria control this century have been largely due to distribution of long-lasting insecticidal nets (LLINs), with many SSA countries planning campaigns for 2020. Here we use COVID-19 and malaria transmission models to estimate the impact of disruption of malaria prevention activities and other core health services under different COVID-19 epidemic scenarios. If activities are halted, the malaria burden in 2020 could be more than double that of 2019. Mitigating this negative impact is possible, and LLIN distributions in particular should be prioritised alongside access to antimalarial treatment to prevent substantial malaria epidemics.

Published
2020

41. Geographical and temporal variation in reduction of malaria infection among children under 5 years of age throughout Nigeria

Author

Oyibo, Wellington, primary, Ntadom, Godwin, additional, Uhomoibhi, Perpetua, additional, Oresanya, Olusola, additional, Ogbulafor, Nnenna, additional, Ajumobi, Olufemi, additional, Okoh, Festus, additional, Maxwell, Kolawole, additional, Ezeiru, Sonachi, additional, Nwokolo, Ernest, additional, Amajoh, Chioma, additional, Ezeigwe, Nnenna, additional, Audu, Mohammed, additional, and Conway, David, additional

Published
2021
Full Text
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42. Geographical and temporal variation in reduction of malaria infection among children under five years of age throughout Nigeria

Author

Oyibo, Wellington, primary, Ntadom, Godwin, additional, Uhomoibhi, Perpetua, additional, Oresanya, Olusola, additional, Ogbulafor, Nnenna, additional, Ajumobi, Olufemi, additional, Okoh, Festus, additional, Maxwell, Kolawole, additional, Ezeiru, Sonachi, additional, Nwokolo, Ernest, additional, Amajoh, Chioma, additional, Ezeigwe, Nnenna, additional, Audu, Mohammed, additional, and Conway, David J., additional

Published
2021
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44. Validating functional health facilities and capacity for improved disease surveillance through DHIS2: Experience from Kano and Zamfara States, Nigeria

Author

Usaini Bala, Olufemi Ajumobi, Umar, Amina, Adefisoye Adewole, Ndadilnasiya Waziri, Saheed Gidado, Ieren Isaac, Ugbenyo, Gideon, Simple, Edwin, Gurusu, Muhammad, Binjing, Mathew, Abdulkarim Zubair, Jega, Yusuf, Talatu Tadi, Tasiu Habib, Shuayb, Fatima, Yahaya, Mohammed, Abubakar, Jafar, Alhassan Da'u, Audu B Mohammed, Uhomoibhi, Perpetua, Muhammad, Basheer, Ismail, Munira, Cash, Shelby, and Kwame Asamoa

Published
2018
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45. Additional file 2: of Setting a Nigeria national malaria operational research agenda: the process

Author

Olufemi Ajumobi, Uhomoibhi, Perpetua, Onyiah, Pamela, Obafemi Babalola, Salami Sharafadeen, Maduka Ughasoro, Al-Mukhtar Adamu, Oluwaseun Odeyinka, Taiwo Orimogunje, Maikore, Ibrahim, Shekarau, Emmanuel, Akintayo Ogunwale, Rotimi Afolabi, Udeh, Sylvester, Akpuh Ndubuisi, Ntiense Umoette, Nguku, Patrick, and IkeOluwapo Ajayi

Abstract

Nigeria National Malaria Operational Research Agenda Online Survey questionnaire. (DOC 144 kb)

Published
2018
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46. Additional file 3: of Setting a Nigeria national malaria operational research agenda: the process

Author

Olufemi Ajumobi, Uhomoibhi, Perpetua, Onyiah, Pamela, Obafemi Babalola, Salami Sharafadeen, Maduka Ughasoro, Al-Mukhtar Adamu, Oluwaseun Odeyinka, Taiwo Orimogunje, Maikore, Ibrahim, Shekarau, Emmanuel, Akintayo Ogunwale, Rotimi Afolabi, Udeh, Sylvester, Akpuh Ndubuisi, Ntiense Umoette, Nguku, Patrick, and IkeOluwapo Ajayi

Subjects
3. Good health
Abstract

Nigeria National Malaria Operational Research Agenda Key Informant Interview Guide. (PDF 44 kb)

47. Additional file 1: of Setting a Nigeria national malaria operational research agenda: the process

Author

Olufemi Ajumobi, Uhomoibhi, Perpetua, Onyiah, Pamela, Obafemi Babalola, Salami Sharafadeen, Maduka Ughasoro, Al-Mukhtar Adamu, Oluwaseun Odeyinka, Taiwo Orimogunje, Maikore, Ibrahim, Shekarau, Emmanuel, Akintayo Ogunwale, Rotimi Afolabi, Udeh, Sylvester, Akpuh Ndubuisi, Ntiense Umoette, Nguku, Patrick, and IkeOluwapo Ajayi

Subjects
3. Good health
Abstract

List of Reviewed Documents from the National Malaria Elimination Programme (available at www.nmcp.gov.ng/archives , accessed 2016 October 7). (DOCX 29 kb)

48. Additional file 3: of Setting a Nigeria national malaria operational research agenda: the process

Author

Olufemi Ajumobi, Uhomoibhi, Perpetua, Onyiah, Pamela, Obafemi Babalola, Salami Sharafadeen, Maduka Ughasoro, Al-Mukhtar Adamu, Oluwaseun Odeyinka, Taiwo Orimogunje, Maikore, Ibrahim, Shekarau, Emmanuel, Akintayo Ogunwale, Rotimi Afolabi, Udeh, Sylvester, Akpuh Ndubuisi, Ntiense Umoette, Nguku, Patrick, and IkeOluwapo Ajayi

Subjects
3. Good health
Abstract

Nigeria National Malaria Operational Research Agenda Key Informant Interview Guide. (PDF 44 kb)

49. Additional file 1: of Setting a Nigeria national malaria operational research agenda: the process

Author

Olufemi Ajumobi, Uhomoibhi, Perpetua, Onyiah, Pamela, Obafemi Babalola, Salami Sharafadeen, Maduka Ughasoro, Al-Mukhtar Adamu, Oluwaseun Odeyinka, Taiwo Orimogunje, Maikore, Ibrahim, Shekarau, Emmanuel, Akintayo Ogunwale, Rotimi Afolabi, Udeh, Sylvester, Akpuh Ndubuisi, Ntiense Umoette, Nguku, Patrick, and IkeOluwapo Ajayi

Subjects
3. Good health
Abstract

List of Reviewed Documents from the National Malaria Elimination Programme (available at www.nmcp.gov.ng/archives , accessed 2016 October 7). (DOCX 29 kb)

50. A cluster-randomized trial of client and provider directed financial interventions to align incentives with appropriate case management in private medicine retailers: Results of the TESTsmART trial in Lagos, Nigeria.

Author

Visser T, Laktabai J, Kimachas E, Kipkoech J, Menya D, Arthur D, Zhou Y, Chepkwony T, Abel L, Robie E, Amunga M, Ambani G, Uhomoibhi P, Ogbulafor N, Oshinowo A, Ogunsola O, Woldeghebriel M, Garber E, Olaleye T, Eze N, Nwidae L, Mudabai P, Gallis JA, Fashanu C, Saran I, Woolsey A, Wiwa O, Turner EL, and Prudhomme O'Meara W

Abstract

Malaria remains a major health priority in Nigeria. Among children with fever who seek care, less than a quarter gets tested for malaria, leading to inappropriate use of the recommended treatment for malaria; Artemisinin-based Combination Therapy (ACT). Here we test an innovative strategy to target ACT subsidies to clients seeking care in Nigeria's private retail health sector who have a confirmed malaria diagnosis. We supported point-of-care malaria testing (mRDTs) in 48 Private Medicine Retailers (PMRs) in the city of Lagos, Nigeria and randomized them to two study arms; a control arm offering subsidized mRDT testing for USD $0.66, and an intervention arm where, in addition to access to subsidized testing as in the control arm, clients who received a positive mRDT at the PMR were eligible for a free (fully subsidized) first-line ACT and PMRs received USD $0.2 for every mRDT performed. Our primary outcome was the proportion of ACTs dispensed to individuals with a positive diagnostic test. Secondary outcomes included proportion of clients who were tested at the PMR and adherence to diagnostic test results. Overall, 23% of clients chose to test at the PMR. Test results seemed to inform treatment decisions and resulted in enhanced targeting of ACTs to confirmed malaria cases with only 26% of test-negative clients purchasing an ACT compared to 58% of untested clients. However, the intervention did not offer further improvements, compared to the control arm, in testing rates or dispensing of ACTs to test-positive clients. We found that ACT subsidies were not passed on to clients testing positive in the intervention arm. We conclude that mRDTs could reduce ACT overconsumption in Nigeria's private retail health sector, but PMR-oriented incentive structures are difficult to implement and may need to be complemented with interventions targeting clients of PMRs to increase test uptake and adherence. Trials registration: Clinical Trials Registration Number: NCT04428307. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816435/ Correction: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9476591/., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Visser et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Published
2024
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