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26 results on '"Ulysse, Christine A."'

1. Fostering Inclusivity in Research Engagement for Underrepresented Populations in Parkinson's Disease: The FIRE-UP PD study

Author

Ison, Juliana M., Jackson, Jonathan D., Hemley, Helen, Willis, Allison, Siddiqi, Bernadette, Macklin, Eric A., Ulysse, Christine, Fitts, Michael S., Pham, Tiffany T.-H., Afshari, Mitra, Agarwal, Pinky, Aminoff, Michael, Bissonnette, Stephanie, Fullard, Michelle, Khan, Tarannum S., Larson, Danielle N., Wielinski, Catherine, and Sanchez, Angie V.

Published
2024
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2. Association of Race and Ethnicity with Sedation Management in Pediatric Intensive Care.

Author

Natale, JoAnne E, Asaro, Lisa A, Joseph, Jill G, Ulysse, Christine, Ascenzi, Judith, Bowens, Cindy, Wypij, David, Curley, Martha AQ, and RESTORE Study Investigators

Subjects
RESTORE Study Investigators, Humans, Respiratory Insufficiency, Pain, Respiration, Artificial, Critical Care, Adolescent, Child, Child, Preschool, Infant, Infant, Newborn, Intensive Care Units, Pediatric, Female, Male, Multicenter Studies as Topic, Randomized Controlled Trials as Topic, Healthcare Disparities, Pain Management, Ethnicity, Hispanic or Latino, White People, Black People, artificial, child, disparities, respiration, withdrawal, Clinical Trials and Supportive Activities, Patient Safety, Pediatric, Clinical Research, Chronic Pain, Pain Research
Abstract

Rationale: Racial disparities in pain management have been previously reported for children receiving emergency care.Objectives: To determine whether patient race or ethnicity is associated with the broader goal of pain management and sedation among pediatric patients mechanically ventilated for acute respiratory failure.Methods: Planned secondary analysis of RESTORE (Randomized Evaluation of Sedation Titration for Respiratory Failure). RESTORE, a cluster-randomized clinical trial conducted in 31 U.S. pediatric intensive care units, compared protocolized sedation management (intervention arm) with usual care (control arm). Participants included 2,271 children identified as non-Hispanic white (white, n = 1,233), non-Hispanic Black (Black, n = 502), or Hispanic of any race (Hispanic, n = 536).Results: Within each treatment arm, neither opioid nor benzodiazepine selection, nor cumulative dosing, differed significantly among race and ethnicity groups. Black patients experienced fewer days with an episode of pain (compared with white patients in the control arm and with Hispanic patients in the intervention arm) and experienced less iatrogenic withdrawal syndrome (compared with white patients in either arm or with Hispanic patients in the intervention arm). The percentage of days awake and calm while intubated was not significantly different in pairwise comparisons by race and ethnicity groups in either the control arm (median: white, 75%; Black, 71%; Hispanic, 75%) or the intervention arm (white, 86%; Black, 88%; Hispanic, 85%).Conclusions: Across multiple measures, our study found scattered differences in sedation management among critically ill Black, Hispanic, and white children that did not consistently favor any group. However, racial disparities related to implicit bias cannot be completely ruled out.Clinical trial registered with clinicaltrials.gov (NCT00814099).

Published
2021

3. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome

Author

Moss, Marc, Huang, David T, Brower, Roy G, Ferguson, Niall D, Ginde, Adit A, Gong, MN, Grissom, Colin K, Gundel, Stephanie, Hayden, Douglas, Hite, R Duncan, Hou, Peter C, Hough, Catherine L, Iwashyna, Theodore J, Khan, Akram, Liu, Kathleen D, Talmor, Daniel, Thompson, B Taylor, Ulysse, Christine A, Yealy, Donald M, and Angus, Derek C

Subjects
Clinical Research, Lung, Bioengineering, Cardiovascular, Acute Respiratory Distress Syndrome, Rare Diseases, Clinical Trials and Supportive Activities, Respiratory, Good Health and Well Being, Adult, Aged, Atracurium, Combined Modality Therapy, Conscious Sedation, Female, Hospital Mortality, Humans, Male, Middle Aged, Neuromuscular Blockade, Neuromuscular Blocking Agents, Positive-Pressure Respiration, Respiratory Distress Syndrome, Treatment Failure, National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundThe benefits of early continuous neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation remain unclear.MethodsWe randomly assigned patients with moderate-to-severe ARDS (defined by a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen of

Published
2019

4. Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial.

Author

Natale, Joanne E, Lebet, Ruth, Joseph, Jill G, Ulysse, Christine, Ascenzi, Judith, Wypij, David, Curley, Martha AQ, and Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators

Subjects
Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) Study Investigators, Humans, Critical Care, Parents, Refusal to Participate, Child, Child, Preschool, Infant, Female, Male, Hispanic or Latino, White People, Black or African American, RESTORE, cluster randomized trial, disparity, Pediatric, Clinical Trials and Supportive Activities, Behavioral and Social Science, Prevention, Patient Safety, Clinical Research, Management of diseases and conditions, 7.3 Management and decision making, African Americans, Whites, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo evaluate whether race or ethnicity was independently associated with parental refusal of consent for their child's participation in a multisite pediatric critical care clinical trial.Study designWe performed a secondary analyses of data from Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE), a 31-center cluster randomized trial of sedation management in critically ill children with acute respiratory failure supported on mechanical ventilation. Multivariable logistic regression modeling estimated associations between patient race and ethnicity and parental refusal of study consent.ResultAmong the 3438 children meeting enrollment criteria and approached for consent, 2954 had documented race/ethnicity of non-Hispanic White (White), non-Hispanic Black (Black), or Hispanic of any race. Inability to approach for consent was more common for parents of Black (19.5%) compared with White (11.7%) or Hispanic children (13.2%). Among those offered consent, parents of Black (29.5%) and Hispanic children (25.9%) more frequently refused consent than parents of White children (18.2%, P

Published
2017

5. Supplementary Data from Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas

Author

Wo, Jennifer Y., primary, Clark, Jeffrey W., primary, Eyler, Christine E., primary, Mino-Kenudson, Mari, primary, Klempner, Samuel J., primary, Allen, Jill N., primary, Keane, Florence K., primary, Parikh, Aparna R., primary, Roeland, Eric, primary, Drapek, Lorraine C., primary, Ryan, David P., primary, Corcoran, Ryan B., primary, Van Seventer, Emily, primary, Fetter, Isobel J., primary, Shahzade, Heather A., primary, Khandekar, Melin J., primary, Lanuti, Michael, primary, Morse, Christopher R., primary, Heist, Rebecca S., primary, Ulysse, Christine A., primary, Christopher, Benjamin, primary, Baglini, Christian, primary, Yeap, Beow Y., primary, Mullen, John T., primary, and Hong, Theodore S., primary

Published
2023
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6. Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial

Author

Curley, Martha A.Q., Wypij, David, Allen, Geoffrey L., Angus, Derek C., Asaro, Lisa A., Ascenzi, Judy A., Bateman, Scot T., Borasino, Santiago, Bowens, Cindy Darnell, Bysani, G. Kris, Cheifetz, Ira M., Cowl, Allison S., Dodson, Brenda L., Faustino, E. Vincent S., Fineman, Lori D., Flori, Heidi R., Franck, Linda S., Gedeit, Rainer G., Grant, Mary Jo C., Harabin, Andrea L., Haskins-Kiefer, Catherine, Hertzog, James H., Hutchins, Larissa, Kirby, Aileen L., Lebet, Ruth M., Matthay, Michael A., McLaughlin, Gwenn E., Natale, Joanne E., Oren, Phineas P., Polavarapu, Nagendra, Schneider, James B., Schwarz, Adam J., Shanley, Thomas P., Simone, Shari, Singer, Lewis P., Sorce, Lauren R., Truemper, Edward J., Vander Heyden, Michele A., Watson, R. Scott, Wells, Claire R., Lebet, Ruth, Joseph, Jill G., Ulysse, Christine, and Ascenzi, Judith

Published
2017
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11. Characteristics and Outcomes of US Patients Hospitalized With COVID-19

Author

Peltan, Ithan D., primary, Caldwell, Ellen, additional, Admon, Andrew J., additional, Attia, Engi F., additional, Gundel, Stephanie J., additional, Mathews, Kusum S., additional, Nagrebetsky, Alexander, additional, Sahetya, Sarina K., additional, Ulysse, Christine, additional, Brown, Samuel M., additional, Chang, Steven Y., additional, Goodwin, Andrew J., additional, Hope, Aluko A., additional, Iwashyna, Theodore J., additional, Johnson, Nicholas J., additional, Lanspa, Michael J., additional, Richardson, Lynne D., additional, Vranas, Kelly C., additional, Angus, Derek C., additional, Baron, Rebecca M., additional, Haaland, Benjamin A., additional, Hayden, Douglas L., additional, Thompson, B. Taylor, additional, Rice, Todd W., additional, and Hough, Catherine L., additional

Published
2022
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12. Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas

Author

Wo, Jennifer Y., primary, Clark, Jeffrey W., additional, Eyler, Christine E., additional, Mino-Kenudson, Mari, additional, Klempner, Samuel J., additional, Allen, Jill N., additional, Keane, Florence K., additional, Parikh, Aparna R., additional, Roeland, Eric, additional, Drapek, Lorraine C., additional, Ryan, David P., additional, Corcoran, Ryan B., additional, Van Seventer, Emily, additional, Fetter, Isobel J., additional, Shahzade, Heather A., additional, Khandekar, Melin J., additional, Lanuti, Michael, additional, Morse, Christopher R., additional, Heist, Rebecca S., additional, Ulysse, Christine A., additional, Christopher, Benjamin, additional, Baglini, Christian, additional, Yeap, Beow Y., additional, Mullen, John T., additional, and Hong, Theodore S., additional

Published
2021
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13. Assessment of a Contralateral Esophagus–Sparing Technique in Locally Advanced Lung Cancer Treated With High-Dose Chemoradiation

Author

Kamran, Sophia C., primary, Yeap, Beow Y., additional, Ulysse, Christine A., additional, Cronin, Catherine, additional, Bowes, Cynthia L., additional, Durgin, Brittany, additional, Gainor, Justin F., additional, Khandekar, Melin J., additional, Tansky, Joanna Y., additional, Keane, Florence K., additional, Olsen, Christine C., additional, and Willers, Henning, additional

Published
2021
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14. Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19

Author

Self, Wesley H., Semler, Matthew W., Leither, Lindsay M., Casey, Jonathan D., Angus, Derek C., Brower, Roy G., Chang, Steven Y., Collins, Sean P., Eppensteiner, John C., Filbin, Michael R., Files, D. Clark, Gibbs, Kevin W., Ginde, Adit A., Gong, Michelle N., Harrell Jr, Frank E., Hayden, Douglas L., Hough, Catherine L., Johnson, Nicholas J., Khan, Akram, Lindsell, Christopher J., Matthay, Michael A., Moss, Marc, Park, Pauline K., Rice, Todd W., Robinson, Bryce R. H., Schoenfeld, David A., Shapiro, Nathan I., Steingrub, Jay S., Ulysse, Christine A., Weissman, Alexandra, Yealy, Donald M., Thompson, B. Taylor, and Brown, Samuel M.

Subjects
General Medicine
Published
2020
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15. Local and systemic recurrence following total neoadjuvant therapy (TNT) and resection for borderline resectable and locally advanced pancreatic adenocarcinoma: Long-term follow up from two phase II studies.

Author

Ryan, Grace E., primary, Murphy, Janet E., additional, Ulysse, Christine A., additional, Yeap, Beow Y., additional, Wo, Jennifer Yon-Li, additional, Weekes, Colin D., additional, Clark, Jeffrey William, additional, Allen, Jill N., additional, Blaszkowsky, Lawrence Scott, additional, Nipp, Ryan David, additional, Drapek, Lorraine C., additional, Parikh, Aparna Raj, additional, Bolton, Christine, additional, Maruna, Jacob, additional, Ferrone, Cristina R., additional, Qadan, Motaz, additional, Lillemoe, Keith D., additional, Ryan, David P., additional, Fernandez Del-Castillo, Carlos, additional, and Hong, Theodore S., additional

Published
2021
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16. The use of elevated circulating hepatocyte growth factor (HGF) level as a potential prognostic biomarker in locally advanced pancreatic cancer.

Author

Roberts, Hannah Johnson, primary, Wo, Jennifer Yon-Li, additional, Yeap, Beow Y., additional, Ulysse, Christine A., additional, Murphy, Janet E., additional, Weekes, Colin D., additional, Ryan, David P., additional, Clark, Jeffrey William, additional, Ferrone, Cristina R., additional, Lillemoe, Keith D., additional, Qadan, Motaz, additional, Fernandez-del Castillo, Carlos, additional, Jain, Rakesh K., additional, Hong, Theodore S., additional, and Duda, Gabriel Dan, additional

Published
2021
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17. Results and molecular correlates from a pilot study of neoadjuvant induction FOLFIRINOX followed by chemoradiation and surgery for gastroesophageal adenocarcinomas

Author

Wo, Jennifer, primary, Clark, Jeffrey, additional, Eyler, Christine, additional, Mino-Kenudson, Mari, additional, Klempner, Samuel, additional, Allen, Jill, additional, Keane, Florence, additional, Parikh, Aparna, additional, Roeland, Eric, additional, Drapek, Lorraine, additional, Ryan, David, additional, Corcoran, Ryan, additional, Seventer, Emily van, additional, Fetter, Isobel, additional, Shahzade, Heather, additional, Khandekar, Melin, additional, Lanuti, Michael, additional, Morse, Christopher, additional, Heist, Rebecca, additional, Ulysse, Christine, additional, Christopher, Benjamin, additional, Baglini, Christian, additional, Yeap, Beow, additional, Mullen, John, additional, and Hong, Theodore, additional

Published
2020
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19. A pilot study of durvalumab/tremelimumab (durva/treme) and radiation (XRT) for metastatic biliary tract cancer (mBTC): Preliminary safety and efficacy.

Author

Hong, Theodore S., primary, Goyal, Lipika, additional, Parikh, Aparna Raj, additional, Yeap, Beow Y., additional, Ulysse, Christine A., additional, Drapek, Lorraine C., additional, Allen, Jill N., additional, Clark, Jeffrey William, additional, Christopher, Benjamin, additional, Bolton, Christine, additional, Ryan, David P., additional, Corcoran, Ryan Bruce, additional, Meyerhardt, Jeffrey A., additional, Wo, Jennifer Yon-Li, additional, and Zhu, Andrew X., additional

Published
2020
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20. Early Neuromuscular Blockade in the Acute Respiratory Distress Syndrome

Author

National Heart, Lung, and Blood Institute PETAL Clinical Trials Network, Moss, Marc, Huang, David T, Brower, Roy G, Ferguson, Niall D, Ginde, Adit A, Gong, MN, Grissom, Colin K, Gundel, Stephanie, Hayden, Douglas, Hite, R Duncan, Hou, Peter C, Hough, Catherine L, Iwashyna, Theodore J, Khan, Akram, Liu, Kathleen D, Talmor, Daniel, Thompson, B Taylor, Ulysse, Christine A, Yealy, Donald M, and Angus, Derek C

Subjects
Adult, Male, Clinical Trials and Supportive Activities, Conscious Sedation, Bioengineering, Cardiovascular, Medical and Health Sciences, Positive-Pressure Respiration, Rare Diseases, Clinical Research, General & Internal Medicine, Humans, Treatment Failure, Hospital Mortality, Lung, Acute Respiratory Distress Syndrome, Aged, Respiratory Distress Syndrome, National Heart, Middle Aged, Combined Modality Therapy, Good Health and Well Being, Atracurium, Neuromuscular Blockade, Respiratory, and Blood Institute PETAL Clinical Trials Network, Female, Neuromuscular Blocking Agents
Abstract

BackgroundThe benefits of early continuous neuromuscular blockade in patients with acute respiratory distress syndrome (ARDS) who are receiving mechanical ventilation remain unclear.MethodsWe randomly assigned patients with moderate-to-severe ARDS (defined by a ratio of the partial pressure of arterial oxygen to the fraction of inspired oxygen of

Published
2019

21. A pilot study of neoadjuvant FOLFIRINOX followed by chemoradiation for gastric and gastroesophageal cancer: Preliminary results.

Author

Wo, Jennifer Yon-Li, primary, Clark, Jeffrey William, additional, Allen, Jill N., additional, Blaszkowsky, Lawrence Scott, additional, Keane, Florence, additional, Drapek, Lorraine C., additional, Ryan, David P., additional, Corcoran, Ryan Bruce, additional, Roeland, Eric, additional, Parikh, Aparna Raj, additional, Khandekar, Melin Janardan, additional, Heist, Rebecca Suk, additional, Morse, Christopher, additional, Yeap, Beow Y., additional, Ulysse, Christine A, additional, Christopher, Benjamin, additional, Lanuti, Michael, additional, Berger, David L., additional, Mullen, John Thomas, additional, and Hong, Theodore S., additional

Published
2019
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24. Racial and Ethnic Disparities in Parental Refusal of Consent in a Large, Multisite Pediatric Critical Care Clinical Trial

Author

Natale, Joanne E., primary, Lebet, Ruth, additional, Joseph, Jill G., additional, Ulysse, Christine, additional, Ascenzi, Judith, additional, Wypij, David, additional, Curley, Martha A.Q., additional, Allen, Geoffrey L., additional, Angus, Derek C., additional, Asaro, Lisa A., additional, Ascenzi, Judy A., additional, Bateman, Scot T., additional, Borasino, Santiago, additional, Bowens, Cindy Darnell, additional, Bysani, G. Kris, additional, Cheifetz, Ira M., additional, Cowl, Allison S., additional, Dodson, Brenda L., additional, Faustino, E. Vincent S., additional, Fineman, Lori D., additional, Flori, Heidi R., additional, Franck, Linda S., additional, Gedeit, Rainer G., additional, Grant, Mary Jo C., additional, Harabin, Andrea L., additional, Haskins-Kiefer, Catherine, additional, Hertzog, James H., additional, Hutchins, Larissa, additional, Kirby, Aileen L., additional, Lebet, Ruth M., additional, Matthay, Michael A., additional, McLaughlin, Gwenn E., additional, Natale, Joanne E., additional, Oren, Phineas P., additional, Polavarapu, Nagendra, additional, Schneider, James B., additional, Schwarz, Adam J., additional, Shanley, Thomas P., additional, Simone, Shari, additional, Singer, Lewis P., additional, Sorce, Lauren R., additional, Truemper, Edward J., additional, Vander Heyden, Michele A., additional, Watson, R. Scott, additional, and Wells, Claire R., additional

Published
2017
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