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24 results on '"Umeda, Kouji"'

1. Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea among pediatric patients

Author

Rahman, Shofiqur, Higo-Moriguchi, Kyoko, Htun, Khaing Win, Taniguchi, Koki, Icatlo, Faustino C., Jr., Tsuji, Takao, Kodama, Yoshikatsu, Van Nguyen, Sa, Umeda, Kouji, Oo, Htun Naing, Myint, Yi Yi, Htut, Than, Myint, Swe Swe, Thura, Kyaw, Thu, Hlaing Myat, Fatmawati, Ni Nengah Dwi, and Oguma, Keiji

Published
2012
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6. Chicken Egg Yolk Antibodies (IgY) for Prophylaxis and Treatment of Rotavirus Diarrhea in Human and Animal Neonates: A Concise Review

Author

Thu, Hlaing Myat, primary, Myat, Theingi Win, additional, Win, Mo Mo, additional, Thant, Kyaw Zin, additional, Rahman, Shofiqur, additional, Umeda, Kouji, additional, Nguyen, Sa Van, additional, Icatlo, Faustino C. Jr., additional, Higo-Moriguchi, Kyoko, additional, Taniguchi, Koki, additional, Tsuji, Takao, additional, Oguma, Keiji, additional, Kim, Sang Jong, additional, Bae, Hyun Suk, additional, and Choi, Hyuk Joon, additional

Published
2017
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7. High Prevalence of G12 Human Rotaviruses in Children with Gastroenteritis in Myanmar

Author

Ide, Tomihiko, primary, Higo-Moriguchi, Kyoko, additional, Komoto, Satoshi, additional, Htun, Khaing Win, additional, Myint, Yi Yi, additional, Myat, Theingi Win, additional, Thant, Kyaw Zin, additional, Thu, Hlaing Myat, additional, Win, Mo Mo, additional, Oo, Htun Naing, additional, Htut, Than, additional, Rahman, Shofiqur, additional, Nguyen, Sa Van, additional, Umeda, Kouji, additional, Oguma, Keiji, additional, Tsuji, Takao, additional, and Taniguchi, Koki, additional

Published
2016
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8. Evaluation of lozenges containing egg yolk antibody against Porphyromonas gingivalis gingipains as an adjunct to conventional non-surgical therapy in periodontitis patients: A randomized controlled clinical trial.

Author

Nguyen, Sa V., Nguyen, Minh T.H., Tran, Binh C., Ho, Minh T.Q., Umeda, Kouji, and Rahman, Shofiqur

Abstract

Background: In a previous pilot study, one-time application of anti-Porphyromonas gingivalis gingipain egg yolk immunoglobulin (IgY) into scaling and root planing (SRP)-treated periodontal pockets showed profound improvement of clinical and bacteriological parameters in patients with chronic periodontitis. The present study aims to evaluate the efficacy of daily use of lozenges fortified with the antibody as an adjunct to non-surgical therapy in patients with periodontitis.Methods: Sixty-four patients with periodontitis were divided randomly into a test and a placebo group. The groups were treated by SRP followed by a daily use of lozenges containing either specific IgY against P. gingivalis gingipains (test) or a sham-immune IgY (placebo). Gingival bleeding index (GBI), probing pocket depth (PD) and quantitation of P. gingivalis in the gingival pockets were assessed at baseline and 8 weeks after the initiation of treatment and compared by using Wilcoxon signed rank test, Mann-Whitney U-test or t test.Results: Both groups showed significant improvement of all parameters at 8 weeks post treatment (P < 0.001). There was a significant difference in reduction of GBI (P < 0.001) and P. gingivalis cell counts (P < 0.05) in the test group compared with the placebo group. The reduction of PD was greater in the test group compared with the placebo group although there was no statistically significant difference between the two groups.Conclusions: The adjunctive use of lozenges containing IgY antibody against gingipains from P. gingivalis resulted in clinical and microbiological benefits in the treatment for chronic periodontitis. Additional investigations are needed to examine if the IgY brings benefits to case patients who do not receive SRP. [ABSTRACT FROM AUTHOR]

Published
2018
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9. Whole Genomic Analysis of Human G12P[6] and G12P[8] Rotavirus Strains that Have Emerged in Myanmar

Author

Ide, Tomihiko, primary, Komoto, Satoshi, additional, Higo-Moriguchi, Kyoko, additional, Htun, Khaing Win, additional, Myint, Yi Yi, additional, Myat, Theingi Win, additional, Thant, Kyaw Zin, additional, Thu, Hlaing Myat, additional, Win, Mo Mo, additional, Oo, Htun Naing, additional, Htut, Than, additional, Wakuda, Mitsutaka, additional, Dennis, Francis Ekow, additional, Haga, Kei, additional, Fujii, Yoshiki, additional, Katayama, Kazuhiko, additional, Rahman, Shofiqur, additional, Nguyen, Sa Van, additional, Umeda, Kouji, additional, Oguma, Keiji, additional, Tsuji, Takao, additional, and Taniguchi, Koki, additional

Published
2015
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10. Passive protection of dogs against clinical disease due to Canine parvovirus-2 by specific antibody from chicken egg yolk

Author

Van Nguyen, Sa, Umeda, Kouji, Yokoyama, Hideaki, Tohya, Yukinobu, and Kodama, Yoshikatsu

Subjects
Parvovirus, Canine, animal diseases, viruses, Short Communications, Immunization, Passive, Antibodies, Viral, Weight Gain, Egg Yolk, Virus Shedding, Parvoviridae Infections, Dogs, Animals, Newborn, Antibody Specificity, Neutralization Tests, Animals, Dog Diseases, Chickens
Abstract

The protective effect of immunoglobulins derived from chicken egg yolk (IgY) against infection by Canine parvovirus 2 (CPV-2) was evaluated in 10 beagle dogs orally challenged with a strain of the virus. The 2-mo-old dogs were divided into 3 groups and treated with powders containing CPV-2 IgY or normal egg yolk for 7 d after the challenge. The 4 dogs receiving normal egg yolk (control group) demonstrated mild symptoms typical of CPV-2 infection, such as vomiting, diarrhea, and weight loss. No symptoms were observed by 16 d after challenge in the 3 dogs receiving 2 g of IgY powder. Of the 3 dogs receiving 0.5 g of IgY powder, 2 had clinical CPV-2 disease; however, the manifestations were less severe than in the control group. Furthermore, the IgY-treated groups had significantly greater weight gain and shorter duration of virus shedding than the control group. These results indicate that IgY is useful in protecting dogs from CPV-2-induced clinical disease.

Published
2006

11. Evaluation of lozenges containing egg yolk antibody against Porphyromonas gingivalisgingipains as an adjunct to conventional non‐surgical therapy in periodontitis patients: A randomized controlled clinical trial

Author

Nguyen, Sa V., Nguyen, Minh T.H., Tran, Binh C., Ho, Minh T.Q., Umeda, Kouji, and Rahman, Shofiqur

Abstract

In a previous pilot study, one‐time application of anti‐Porphyromonas gingivalisgingipain egg yolk immunoglobulin (IgY) into scaling and root planing (SRP)‐treated periodontal pockets showed profound improvement of clinical and bacteriological parameters in patients with chronic periodontitis. The present study aims to evaluate the efficacy of daily use of lozenges fortified with the antibody as an adjunct to non‐surgical therapy in patients with periodontitis. Sixty‐four patients with periodontitis were divided randomly into a test and a placebo group. The groups were treated by SRP followed by a daily use of lozenges containing either specific IgY against P. gingivalisgingipains (test) or a sham‐immune IgY (placebo). Gingival bleeding index (GBI), probing pocket depth (PD) and quantitation of P. gingivalisin the gingival pockets were assessed at baseline and 8 weeks after the initiation of treatment and compared by using Wilcoxon signed rank test, Mann‐Whitney U‐test or ttest. Both groups showed significant improvement of all parameters at 8 weeks post treatment (P < 0.001). There was a significant difference in reduction of GBI (P < 0.001) and P. gingivaliscell counts (P < 0.05) in the test group compared with the placebo group. The reduction of PD was greater in the test group compared with the placebo group although there was no statistically significant difference between the two groups. The adjunctive use of lozenges containing IgY antibody against gingipains from P. gingivalisresulted in clinical and microbiological benefits in the treatment for chronic periodontitis. Additional investigations are needed to examine if the IgY brings benefits to case patients who do not receive SRP.

Published
2018
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22. A CASE OF VILLOUS TUMOR OF THE CECUM

Author

ANDO, Hisami, primary, HIRAIWA, Katsumasa, additional, UMEDA, Kouji, additional, SEO, Takahiko, additional, KISIDA, Yoshihiko, additional, IIO, Kenji, additional, ISHIGURO, Yukio, additional, and ITO, Takahiro, additional

Published
1988
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24. Passive protection of dogs against clinical disease due to Canine parvovirus-2 by specific antibody from chicken egg yolk.

Author

Van Nguyen S, Umeda K, Yokoyama H, Tohya Y, and Kodama Y

Subjects
Animals, Animals, Newborn, Antibody Specificity, Chickens, Dog Diseases virology, Dogs, Egg Yolk, Immunization, Passive methods, Neutralization Tests veterinary, Parvoviridae Infections prevention & control, Parvoviridae Infections virology, Virus Shedding, Weight Gain, Antibodies, Viral blood, Dog Diseases prevention & control, Immunization, Passive veterinary, Parvoviridae Infections veterinary, Parvovirus, Canine immunology
Abstract

The protective effect of immunoglobulins derived from chicken egg yolk (IgY) against infection by Canine parvovirus 2 (CPV-2) was evaluated in 10 beagle dogs orally challenged with a strain of the virus. The 2-mo-old dogs were divided into 3 groups and treated with powders containing CPV-2 IgY or normal egg yolk for 7 d after the challenge. The 4 dogs receiving normal egg yolk (control group) demonstrated mild symptoms typical of CPV-2 infection, such as vomiting, diarrhea, and weight loss. No symptoms were observed by 16 d after challenge in the 3 dogs receiving 2 g of IgY powder. Of the 3 dogs receiving 0.5 g of IgY powder, 2 had clinical CPV-2 disease; however, the manifestations were less severe than in the control group. Furthermore, the IgY-treated groups had significantly greater weight gain and shorter duration of virus shedding than the control group. These results indicate that IgY is useful in protecting dogs from CPV-2-induced clinical disease.

Published
2006

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