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Introduction: Stroke or Cerebrovascular accident (CVA) is a major cause of disability worldwide. The estimation of serum Total T3, Total T4 and TSH are very much essential in patients with stroke. Any disturbances in thyroid hormones may have negative influence on the outcome of acute phase of strokes. Aims And Objectives: Aims and objective was to estimate the Total T3, Total T4 and TSH of patients with acute Strokeand to compare it with age/sex matched healthy controls. Materials & Methods:This Hospital Based Case Control Study, consist of total 100 subjects out of which 50 were control ,was carried out in Jorhat Medical College & Hospital, Assam for a period of one year, from July 2017 to June 2018. Age more than 40 years of both sexes was included. Estimation for total T3, total T4, and TSH was carried out in Access 2 ImmunoAssay Systems (Beckman Coulter). Cases were selectedrandomly . Results And Observations: Out of 50 Stroke patients ,the age group of 50 - Conclusion: Nonthyroidal illness syndrome (Low T3 syndrome) is observed in the present study with decreased T3 values without alteration of T4 and TSH levels. Further studies with a large sample size should attempt to investigate whether treatment of low T3 syndrome can improve the final outcome.

INTRODUCTION: Obesity, a chronic non-communicable disease, as indicated by the World Health Organization (WHO), is one of the most rapidly growing health problems worldwide. Obesity affects the respiratory functions and impairs the gas exchange, leading to alterations in pulmonary function tests (PFT).Younger generation and medical students are no exception in regards to the detrimental effects of obesity.Forced vital capacity (FVC),Forced Expiratory st Volume in 1 second (FEV ), Peak Expiratory Flow Rate (PEFR) are reliable pulmonary function tests to diagnose any 1 respiratory disorder.In this study,FVC,FEV ,PEFR of medical students were assessed to find their relationship with Body 1 Mass Index (BMI). MATERIALS AND METHODS:A institution based cross-sectional observational study was done in Dept.of Physiology,Jorhat Medical College including the undergraduate medical students.Sample size was calculated as 160 using EpiTools Software.Height in centimeters,weight in kilograms and digital spirometry of 160 students were recorded. In case of more than two variables, P values were calculated using Anova Test and p value < 0.05 was considered significant. RESULTS: FVC,FEV ,PEFR all were decreased in overweight and obese students compared to 1 normal weight students and our observation was statistically significant in case of FEV and PEFR by Anova test (p value: 1 0.0335 and 0.0428 respectively. CONCLUSION: Changing of life style that includes performing regular physical exercises,yoga,meditation,sticking to a routine time table for sports,study and sleeping hours and regular health check up in the form of Height,Weight, Spirometry could be beneficial for the students to prevent obesity related pulmonary ailments.

Introduction:diabetes mellitus is a metabolic disorder prevalent worldwide . Oxidative stress has been the Cause of complications which arises gradually due to prolonged hyperglycemia. Vitamin c being a potent antioxidant is well consumed in diabetes mellitus. Methods:Serum samples of diabetes mellitus type 2 patients from jorhat medical college of Assam were tested to estimate ascorbate levels using spectrophotometer. Whole blood samples were tested to estimate glycated hemoglobin levels in d-10 biorad hplc machine. A total of 58 patients and equal numbers of age and sex matched apparently healthy controls were included. Results:significantly lower levels of ascorbate were recorded in diabetic cases compared to controls. Newly diagnosed cases had lesser serum ascorbate levels compared to patients who were on treatment with oral hypoglycemic drugs and insulin. Conclusion:the study was done to look for any alteration in serum ascorbic acid levels in diabetes mellitus patients. Patients newly diagnosed had lesser vitamin c levels compared to patients already on medications. It is found that vitamin c is significantly lower in diabetic patients with or without medications compared to healthy controls.

BACKGROUND SLE (systemic lupus erythematous) is an autoimmune disease, which can lead to damage to any organ in the body mediated by tissue binding autoantibodies. It is not that uncommon in North Eastern part of India. Mainly, the female sex in their reproductive age group are affected. Of all the complications, neuropsychiatric complication is also a common manifestation of SLE. The aim of the study is to- 1. Find the incidence of peripheral neuropathy in SLE patients. 2. Its association with morbidity. MATERIALS AND METHODS Patients were enrolled from 1st September 2010 to 31st August 2011 who attend the Department of Medicine, Assam Medical College, Dibrugarh. A total of 73 patients were enrolled. All patients were above 12 years of age. SLE was diagnosed by 1997 updated ACR criteria. Peripheral neuropathy was diagnosed via nerve conduction velocity test. RESULTS Of the 73 patients, 39 patients had evidence of peripheral neuropathy. Of the 39 patients, 28 patients were asymptomatic. The remaining 11 symptomatic patients mainly complained of pins and needles in their feet and 2 additionally complained of tingling sensation in the lower limbs. CONCLUSION From the study, it is seen that the sural nerve is the most common nerve to be affected in SLE. So, doing Nerve Conduction Study (NCS) on the sural nerve singly could be taken as a screening test to diagnose peripheral neuropathy in SLE patients. But, as the number of patients in the study was less, a study with larger number of patients would be required to confirm that the sural nerve is the most common nerve to be affected in SLE.

BACKGROUND SS occurs due to ischaemic pituitary necrosis after severe Postpartum Haemorrhage (PPH) and is characterised by typical history of severe postpartum blood loss, hypotension or shock, postpartum lactation failure, discontinuation of the menses after the delivery, partial or complete anterior pituitary insufficiency and empty sella on CT or MRI. 1,2,3,4 Although unclear, anaemia is well recognised as a feature of hypopituitarism.