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Your search keyword '"Ute Marlies Bäzner"' showing total 2 results
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2 results on '"Ute Marlies Bäzner"'

1. Comprehensive neurosurgical and visceral surgical therapy of retroperitoneal nerve tumors: a descriptive and retrospective analysis

Author

Martin Petkov, Marko Kornmann, Ute Marlies Bäzner, Lena Minzenmay, Andrej Pala, Maria Teresa Pedro, Christian Rainer Wirtz, and Gregor Antoniadis

Subjects
BPNST, MPNST, Nerve, Tumor, Retroperitoneum, Visceral, Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Nerve tumors in the retroperitoneal space are a rarity. Radical surgery according to soft tissue tumors can lead to persistent pain and neurological deficits. This study aims to evaluate clinical outcomes of patients treated by a visceral- / neurosurgical approach. 33 patients with a retroperitoneal nerve tumor underwent surgery between 01/2002 and 12/2022 at our department. A visceral surgeon provided access to the retroperitoneal space, followed by micro-neurosurgical tumor preparation under neuromonitoring. Clinical examination and MRI were performed 12 weeks after surgery and further 3 months (WHO grade > 1) or 12 months (WHO grade 1). Further examinations were based on MRI findings and residual symptoms with median follow-up time of 24 months. One patient was treated for two distinct masses resulting in a total of 34 histological findings. Schwannomas (n = 15; 44.1%) and neurofibromas (n = 10; 29.4%) were the most common tumors. Long-term improvements were noted in radicular pain (15/18 patients; 83.3%), motor deficits (7/16 patients; 43.8%), abdominal discomfort and pain (5/7 patients; 71.4%). Recurrences were observed in 3/33 (9,1%) patients. This study represents the largest series of retroperitoneal BPNSTs treated with microsurgical techniques. Prospective multicenter studies are warranted to establish standardized treatment guidelines.

Published
2024
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2. Quality of life of patients with neurofibromatosis 1 – physical disability does not necessarily result in inferior mental health

Author

Ute Marlies Bäzner, Leonie Stauss, Thomas Kapapa, Christian Rainer Wirtz, and Andrej Pala

Abstract

Introduction Neurofibromatosis 1 (NF1) is a chronic neurocutaneous disease with tremendous impact on quality of life (QoL). We have performed an analysis of disease severity, mental and physical QoL and compared the different severity classes of patients with neurofibromatosis 1 (NF1). Patients and methods We performed a prospective analysis of 89 patients with NF-1 which are included in the period of 1/2016 - 3/2018. Local records served as data source including demographic data, employment status, level of education, and marital status were evaluated. All patients received 36-Item Short Form Health Survey (SF-36). Additionally, numerical pain rating scale (NPS) Patients were stratified according to different severity of NF-1 and different visibility and severity of disease. Results: Out of 89 patients, severity grad 4 was identified in 42 (47.2%), moderate in 17 (19.1%), mild in 23 (25.8%) and minimal in 7 (7.9%) cases. According to visibility scale, severe grade 3 was found in 28 (31.5%), moderate grade 2 in 26 (29.2%) and mild grade in 35 (39.3%) cases. All SF-36 related data except for pain showed significantly lower values, if compared to the standard German population (p40 was significantly associated with lower physical (p=0.027) but not mental component (p=0.362). According to the numerical pain rating scale, 7-10 were noted in 9 cases (10,1%), 5-6 in 10 patients (11.2%), 1-4 in 26 patients (29.2%) and no pain in 44 cases (49.4%). Physical component showed significant difference between different NPS grades (p

Published
2022
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