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Abstract Background Cleft lip and palate (CLP) are among the most common congenital anomaly that affects up to 33,000 newborns in India every year. Nasoalveolar moulding (NAM) is a non-surgical treatment performed between 0 and 6 months of age to reduce the cleft and improve nasal aesthetics prior to lip surgery. The NAM treatment has been a controversial treatment option with 51% of the cleft teams in Europe, 37% of teams in the USA and 25 of cleft teams in India adopting this methodology. This treatment adds to the already existing high burden of care for these patients. Furthermore, the supporting evidence for this technique is limited with no high-quality long-term clinical trials available on the effectiveness of this treatment. Method The NAMUC study is an investigator-initiated, multi-centre, single-blinded randomized controlled trial with a parallel group design. The study will compare the effectiveness of NAM treatment provided prior to lip surgery against the no-treatment control group in 274 patients with non-syndromic unilateral complete cleft lip and palate. The primary endpoint of the trial is the nasolabial aesthetics measured using the Asher McDade index at 5 years of age. The secondary outcomes include dentofacial development, speech, hearing, cost-effectiveness, quality of life, patient perception, feeding and intangible benefits. Randomization will be carried out via central online system and stratified based on cleft width, birth weight and clinical trial site. Discussion We expect the results from this study on the effectiveness of treatment with NAM appliance in the long term along with the cost-effectiveness evaluation can eliminate the dilemma and differences in clinical care across the globe. Trial registration ClinicalTrials.gov CTRI/2022/11/047426 (Clinical Trials Registry India). Registered on 18 November 2022. The first patient was recruited on 11 December 2022. CTR India does not pick up on Google search with just the trial number. The following steps have to be carried out to pick up. How to search: ( https://ctri.nic.in/Clinicaltrials/advsearch.php —use the search boxes by entering the following details: Interventional trial > November 2022 > NAMUC).

Aim: The aim of the present study is to clarify the possible application of orthopantomogram (OPG) for evaluating craniofacial specifications such as angular and linear measurements of the mandible by comparing with lateral cephalogram. Materials and Methods: OPG and lateral cephalogram were taken from 100 patients of age group 16–35 years from Chettinad Dental College and Research Institute. Linear measurements (body length and ramus height) and angular measurement (gonial angle) were assessed both in lateral cephalogram and OPG. Independent t-test was performed for comparison of OPG and lateral cephalogram using SPSS with a probability level of P < 0.05 considered to be statistically significant. Results: The results of the present study show that there is no statistically significant difference in ramus height and gonial angle when compared between OPG and lateral cephalogram while statistically significant difference exists for body length between OPG and lateral cephalogram. Conclusion: It may be concluded that panoramic radiography can be used to determine the gonial angle and ramus height as accurately as a lateral cephalogram. However, clinicians should be vigilant when predicting horizontal measurement from OPGs.

The nose being the centre of the face and one of the most striking facial features influences the aesthetic outcome of orthodontic therapy. This topic has not received as much emphasis as it should. The nose plays an important role in every aspect of orthodontic therapy such as the diagnosis, treatment planning and post treatment prognosis. Most of the patients treated orthodontically are growing patients. Many a times, both the orthodontist and patient may be satisfied with the facial appearance at the end of orthodontic treatment. But as the growth of the nose continues till about the age of 16, the facial appearance may change. [ABSTRACT FROM AUTHOR]

Background: Cleft lip and palate (CLP) are among the most common congenital anomaly that affects up to 33,000 newborns in India every year. Nasoalveolar moulding (NAM) is a non-surgical treatment performed between 0 and 6 months of age to reduce the cleft and improve nasal aesthetics prior to lip surgery. The NAM treatment has been a controversial treatment option with 51% of the cleft teams in Europe, 37% of teams in the USA and 25 of cleft teams in India adopting this methodology. This treatment adds to the already existing high burden of care for these patients. Furthermore, the supporting evidence for this technique is limited with no high-quality long-term clinical trials available on the effectiveness of this treatment., Method: The NAMUC study is an investigator-initiated, multi-centre, single-blinded randomized controlled trial with a parallel group design. The study will compare the effectiveness of NAM treatment provided prior to lip surgery against the no-treatment control group in 274 patients with non-syndromic unilateral complete cleft lip and palate. The primary endpoint of the trial is the nasolabial aesthetics measured using the Asher McDade index at 5 years of age. The secondary outcomes include dentofacial development, speech, hearing, cost-effectiveness, quality of life, patient perception, feeding and intangible benefits. Randomization will be carried out via central online system and stratified based on cleft width, birth weight and clinical trial site., Discussion: We expect the results from this study on the effectiveness of treatment with NAM appliance in the long term along with the cost-effectiveness evaluation can eliminate the dilemma and differences in clinical care across the globe., Trial Registration: ClinicalTrials.gov CTRI/2022/11/047426 (Clinical Trials Registry India). Registered on 18 November 2022. The first patient was recruited on 11 December 2022. CTR India does not pick up on Google search with just the trial number. The following steps have to be carried out to pick up. How to search: ( https://ctri.nic.in/Clinicaltrials/advsearch.php -use the search boxes by entering the following details: Interventional trial > November 2022 > NAMUC)., (© 2024. The Author(s).)

Aim: The aim of the present study is to clarify the possible application of orthopantomogram (OPG) for evaluating craniofacial specifications such as angular and linear measurements of the mandible by comparing with lateral cephalogram., Materials and Methods: OPG and lateral cephalogram were taken from 100 patients of age group 16-35 years from Chettinad Dental College and Research Institute. Linear measurements (body length and ramus height) and angular measurement (gonial angle) were assessed both in lateral cephalogram and OPG. Independent t -test was performed for comparison of OPG and lateral cephalogram using SPSS with a probability level of P < 0.05 considered to be statistically significant., Results: The results of the present study show that there is no statistically significant difference in ramus height and gonial angle when compared between OPG and lateral cephalogram while statistically significant difference exists for body length between OPG and lateral cephalogram., Conclusion: It may be concluded that panoramic radiography can be used to determine the gonial angle and ramus height as accurately as a lateral cephalogram. However, clinicians should be vigilant when predicting horizontal measurement from OPGs., Competing Interests: There are no conflicts of interest.