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Background. The neck, its bone-cartilaginous and muscle apparatus, etc. high activity is well known. Cervical spine degenerative-dystrophic processes are considered to be an urgent problem. The purpose of the study was to determine the clinical and morphometric changes of the cervical spine in humans and animals with neck pain based on a clinical and neurological examination, determination of the vertebral body density, their configuration, and ratio for timely correction and prognosis of this patho­logy. Materials and methods. Pain intensity was studied in humans and animals using the adapted visual-analogue scale. The inde­xes of computer tomography with measurement of vertebral body density, and morphometric indexes with an emphasis on C5-C7 le­vel were also studied. All studies were conducted following existing bioethical standards. Results. The pathology of spine configuration was registered in 84.6 % of the examined patients in the form of angular kyphosis or straightened lordosis, more often in women. It was observed in 34.7 % of cases in dogs and cats. The normal configuration is more common: in cats — 78.6 % and in dogs of small breeds — 78.5 %, in large breed dogs — only 26.3 %, and deformations were more frequent than in cats and small dogs (2.7 times more). The cervical vertebrae bodies density in all groups decreased toward the caudal direction with a difference of 18.1 % in humans. In cats — 2.7 %, in dogs of small breeds, it was higher (7.5 %), and in large breed dogs, it reached 14.3 %. The maximum deviations of the studied indicators were found in humans and maximally coincided with those in dogs of large breeds. Conclusions. Thus, animals, especially dogs of large breeds, can serve as a model for studying etiopathogenetic factors, the course, prognosis of degeneration of the bone-cartilage apparatus.

Relevance. Mnestic functions in patients after stroke and coronavirus infection are not restored completely. Nowadays, the search for ways to overcome in such patients is actual. Objective: to find out the possibility of cognitive deficiency’ overcoming in persons after stroke who have suffered from COVID-19 by Phenibut pharmacocorrection and magnetic therapy. Materials and methods. 46 patients aged 40-60 years who had COVID-19 in anamnesis and ischemic stroke in the post-covid period were divided into 3 groups at the stage of comprehensive rehabilitation. In the 1st group (n=15) - the control group - no nootropic drugs and physiotherapeutic procedures were not asdministered; in group 2 (n=15), magnet stimulation procedures were performed for 20 days (frequency of basic impulses 180-195 Hz, frequency of a group of impulses 12,5-29 Hz, average induction of magnetic fields within 100 μT); group 3 (n=16) took Phenibut (β-Phenyl-GABA) one tablet (250 mg) 3 times a day for three months. The study of cognitive functions was carried out with the help of a short mental state scale - MMSE, a set of tests for the study of frontal dysfunction - FAB, a test for memorizing of 10 words according to the A.R. Luria’s method and clock drawing testing All groups were tested twice: at the beginning of the study and after three months. The obtained data were processed statistically; an ordinal logistic regression model was applied, in particular logistic regression with a cumulative relationship. The results. In group 2 the result of the subtest "Voluntary attention" improved (3,8±0,3 points vs. 3,1±0,2 in the control) and the FAB test (15, 2±1,2 points vs. 11,3±0,4 in control). In group 3, the cognitive functions in the MMSE (26,1±0,8 points vs. 21,2±0,6 in the control) and FAB (16,3±0,6 points vs. 11,3±0,4) tests probably improved. The results of the subtests "Discretionary attention" (3,8±0,1 points vs. 3,1±0,1) and "Memory" (2,6±0,2 points vs. 2,0±0,1) improved. In the test for 10 words memorizing, the difference in indicators, compared to the control, was in each subsequent presentation: 1,0±0,05; 1,1±0,09; 1,7±0,10 words, in delayed presentation 1,75±0,05 (in all cases p