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468 results on '"VECCHIET, Jacopo"'

2. Ultrasound imaging of the axilla

Author

Cocco, Giulio, Ricci, Vincenzo, Ricci, Costantino, Naňka, Ondřej, Catalano, Orlando, Corvino, Antonio, Boccatonda, Andrea, Serafini, Francesco Lorenzo, Izzi, Jacopo, Vallone, Gianfranco, Cantisani, Vito, Iannetti, Giovanni, Caulo, Massimo, Ucciferri, Claudio, Vecchiet, Jacopo, and Pizzi, Andrea Delli

Published
2023
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3. Ultrasound imaging of bone fractures

Author

Cocco, Giulio, Ricci, Vincenzo, Villani, Michela, Delli Pizzi, Andrea, Izzi, Jacopo, Mastandrea, Marco, Boccatonda, Andrea, Naňka, Ondřej, Corvino, Antonio, Caulo, Massimo, and Vecchiet, Jacopo

Published
2022
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4. Antimicrobial resistance in intensive care patients hospitalized with SEPSIS: a comparison between the COVID-19 pandemic and pre-pandemic era

Author

Falasca, Katia, primary, Vetrugno, Luigi, additional, Borrelli, Paola, additional, Di Nicola, Marta, additional, Ucciferri, Claudio, additional, Gambi, Alessandra, additional, Bazydlo, Magdalena, additional, Taraschi, Giorgia, additional, Vecchiet, Jacopo, additional, and Maggiore, Salvatore Maurizio, additional

Published
2024
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5. Early detection of pleuro‐pulmonary tuberculosis by bedside lung ultrasound: A case report and review of literature

Author

Giulio Cocco, Andrea Boccatonda, Ilaria Rossi, Damiano D’Ardes, Antonio Corvino, Andrea Delli Pizzi, Claudio Ucciferri, Falasca Katia, and Vecchiet Jacopo

Subjects
bedside, lung ultrasound, pleural effusion, tuberculosis, Medicine, Medicine (General), R5-920
Abstract

Abstract We present a case in which lung ultrasound (LUS) was relevant to reach an early diagnosis of lung tuberculosis and to manage the patient in the right setting. Moreover, ultrasound allowed to detect and treat massive pleural effusion through an ultrasound‐guided thoracentesis.

Published
2022
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8. Transcriptomic analysis revealed increased expression of genes involved in keratinization in the tears of COVID-19 patients

Author

Mastropasqua, Leonardo, Toto, Lisa, Chiricosta, Luigi, Diomede, Francesca, Gugliandolo, Agnese, Silvestro, Serena, Marconi, Guya Diletta, Sinjari, Bruna, Vecchiet, Jacopo, Cipollone, Francesco, D’Ardes, Damiano, Auricchio, Antonio, Lanzini, Manuela, Caputi, Sergio, D’Aloisio, Rossella, Mazzon, Emanuela, and Trubiani, Oriana

Published
2021
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9. Radiomics-based machine learning differentiates “ground-glass” opacities due to COVID-19 from acute non-COVID-19 lung disease

Author

Delli Pizzi, Andrea, Chiarelli, Antonio Maria, Chiacchiaretta, Piero, Valdesi, Cristina, Croce, Pierpaolo, Mastrodicasa, Domenico, Villani, Michela, Trebeschi, Stefano, Serafini, Francesco Lorenzo, Rosa, Consuelo, Cocco, Giulio, Luberti, Riccardo, Conte, Sabrina, Mazzamurro, Lucia, Mereu, Manuela, Patea, Rosa Lucia, Panara, Valentina, Marinari, Stefano, Vecchiet, Jacopo, and Caulo, Massimo

Published
2021
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10. HepaDisk – A new quality of life questionnaire for HCV patients

Author

Fagiuoli, Stefano, Caporaso, Nicola, Morisco, Filomena, Buelli, Fabio, Gualberti, Giuliana, Saragaglia, Valeria, Chessa, Luchino, Corti, Giampaolo, Maida, Ivana, Mastroianni, Claudio M., Pirisi, Mario, Russo, Francesco P., Farina, Francesca, Giannitrapani, Lydia, Toniutto, Pierluigi, Tarquini, Pierluigi, Tundo, Paolo, Vecchiet, Jacopo, Vinci, Maria, and Taliani, Gloria

Published
2019
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13. Unexpected rise in the circulation of complex HBV variants enriched of HBsAg vaccine-escape mutations in HBV genotype-D: potential impact on HBsAg detection/quantification and vaccination strategies

Author

Piermatteo, Lorenzo, primary, D’Anna, Stefano, additional, Bertoli, Ada, additional, Bellocchi, Maria, additional, Carioti, Luca, additional, Fabeni, Lavinia, additional, Alkhatib, Mohammad, additional, Frazia, Simone La, additional, Lichtner, Miriam, additional, Mastroianni, Claudio, additional, Sanctis, Giuseppe De, additional, Marignani, Massimo, additional, Pasquazzi, Caterina, additional, Iapadre, Nerio, additional, Parruti, Giustino, additional, Cappiello, Giuseppina, additional, Vecchiet, Jacopo, additional, Malagnino, Vincenzo, additional, Grelli, Sandro, additional, Ceccherini-Silbertein, Francesca, additional, Andreoni, Massimo, additional, Sarmati, Loredana, additional, Svicher, Valentina, additional, and Salpini, Romina, additional

Published
2023
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14. Stable temporal trend of HDV seroprevalence in central Italy across the last two decades with the circulation of HDV sub-genotypes 1 inducing different inflammatory stimuli

Author

Piermatteo, Lorenzo, primary, Salpini, Romina, additional, Torre, Giulia, additional, D’Anna, Stefano, additional, Khan, Sohaib, additional, Duca, Leonardo, additional, Bertoli, Ada, additional, Malagnino, Vincenzo, additional, Di Traglia, Loide, additional, Paba, Pierpaolo, additional, Ciotti, Marco, additional, Lenci, Ilaria, additional, Francioso, Simona, additional, Pasquazzi, Caterina, additional, Lichtner, Miriam, additional, Mastroianni, Claudio M., additional, Santopaolo, Francesco, additional, De Sanctis, Giuseppe Maria, additional, Marignani, Massimo, additional, Pellicelli, Adriano, additional, Galati, Giovanni, additional, Moretti, Alessandra, additional, Casinelli, Katia, additional, Caterini, Luciano, additional, Iapadre, Nerio, additional, Parruti, Giustino, additional, Vecchiet, Jacopo, additional, Maurizio, Paoloni, additional, Grelli, Sandro, additional, Silberstein, Francesca Ceccherini, additional, Sarmati, Loredana, additional, and Svicher, Valentina, additional

Published
2023
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17. Kinetics of hepatitis C virus RNA decay, quasispecies evolution and risk of virological failure during telaprevir-based triple therapy in clinical practice

Author

Cento, Valeria, Tontodonati, Monica, Di Maio, Velia Chiara, Bellocchi, Maria Concetta, Valenti, Fabrizio, Manunta, Alessandra, Fortuna, Serena, Armenia, Daniele, Carioti, Luca, Antonucci, Francesco Paolo, Bertoli, Ada, Trave, Francesca, Cacciatore, Pierluigi, Angelico, Mario, Navarra, Pierluigi, Neumann, Avidan U., Vecchiet, Jacopo, Parruti, Giustino, Babudieri, Sergio, Perno, Carlo Federico, and Ceccherini-Silberstein, Francesca

Published
2015
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18. Hepatitis C virus RNA levels at week-2 of telaprevir/boceprevir administration are predictive of virological outcome

Author

Cento, Valeria, Di Paolo, Daniele, Di Carlo, Domenico, Micheli, Valeria, Tontodonati, Monica, De Leonardis, Francesco, Aragri, Marianna, Antonucci, Francesco Paolo, Di Maio, Velia Chiara, Mancon, Alessandro, Lenci, Ilaria, Manunta, Alessandra, Taliani, Gloria, Di Biagio, Antonio, Nicolini, Laura Ambra, Nosotti, Lorenzo, Sarrecchia, Cesare, Siciliano, Massimo, Landonio, Simona, Pellicelli, Adriano, Gasbarrini, Adriano, Vecchiet, Jacopo, Magni, Carlo Federico, Babudieri, Sergio, Mura, Maria Stella, Andreoni, Massimo, Parruti, Giustino, Rizzardini, Giuliano, Angelico, Mario, Perno, Carlo Federico, and Ceccherini-Silberstein, Francesca

Published
2015
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19. Predictive Value of Echocardiographic Pulmonary to Left Atrial Ratio for In-Hospital Death in Patients with COVID-19

Author

Renda, Giulia, primary, Mennuni, Marco G., additional, Pizzoferrato, Giovanni, additional, Esposto, Daniele, additional, Alberani, Angela, additional, De Vecchi, Simona, additional, Degiovanni, Anna, additional, Giubertoni, Ailia, additional, Spinoni, Enrico Guido, additional, Grisafi, Leonardo, additional, Sagazio, Emanuele, additional, Ucciferri, Claudio, additional, Falasca, Katia, additional, Vecchiet, Jacopo, additional, Gallina, Sabina, additional, and Patti, Giuseppe, additional

Published
2023
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20. Iron Dyshomeostasis in COVID-19: Biomarkers Reveal a Functional Link to 5-Lipoxygenase Activation

Author

Dufrusine, Beatrice, primary, Valentinuzzi, Silvia, additional, Bibbò, Sandra, additional, Damiani, Verena, additional, Lanuti, Paola, additional, Pieragostino, Damiana, additional, Del Boccio, Piero, additional, D’Alessandro, Ersilia, additional, Rabottini, Alberto, additional, Berghella, Alessandro, additional, Allocati, Nerino, additional, Falasca, Katia, additional, Ucciferri, Claudio, additional, Mucedola, Francesco, additional, Di Perna, Marco, additional, Martino, Laura, additional, Vecchiet, Jacopo, additional, De Laurenzi, Vincenzo, additional, and Dainese, Enrico, additional

Published
2022
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31. Association of inflammatory biomarkers and cardiovascular risk scores in an Italian cohort of HIV positive patient undergoing antiretroviral therapy

Author

Falasca Katia, Ucciferri Claudio, Auricchio Antonio, Reale Marcella, Costantini Erica, and Vecchiet Jacopo

Subjects
Infectious Diseases, Virology
Abstract

Background: Several algorithms have been developed to predict cardiovascular risk (CVR) over time, however none of them seem to be accurate when applied to HIV patients. Objective: The aim of this study was to assess plasma inflammatory biomarkers in relation to multiple CVR scores (FRS, ASCVD, PROCAM and the DAD-5 Years-Estimated-Risk) in an Italian cohort of HIV patients undergoing a combined Antiretroviral Therapy (cART). Methods: We enrolled HIV patients undergoing cART without any change in the HIV-related pharmacological therapy over the last 48 weeks Demographic and anamnestic data were collected, and a biochemical panel including the following biomarkers was collected: CRP, Cystatin-C, microalbuminuria, IL-18, IL-2, IL-4, IL-6, IL-10, TNF-α and IFN- γ. CVR scores were obtained for each patient and compared to the biochemical panel to assess statistical correlation. Results: 90 Caucasian HIV patients were enrolled. Assessment of CVR scores showed FRS values of 6.98±6.11%, ASCVD 7.18±6.25%, PROCAM 6.7±7.4% and DAD-5 Years Estimated Risk 3.10±3.41%. We found correlations between the levels of circulating cytokines measured and the cardiovascular risk prediction scores. Conclusions: Our data showed that the values of selected inflammatory biomarkers strongly correlate with the CVR scores, suggesting that they can be employed as reliable predictors of cardiovascular disease in HIV patients. The routine use of selected biomarkers associated with systemic inflammation could be a valid and readily available tool for clinicians to assess and monitor cardiovascular risk in HIV patients.

Published
2021

35. Effects of Probiotic Mixture Supplementation on the Immune Response to the 13-Valent Pneumococcal Conjugate Vaccine in People Living with HIV

Author

Reale, Marcella, primary, Ucciferri, Claudio, additional, Costantini, Erica, additional, Di Nicola, Marta, additional, Porreca, Annamaria, additional, Di Giovanni, Pamela, additional, Pontolillo, Michela, additional, Auricchio, Antonio, additional, Vecchiet, Jacopo, additional, and Falasca, Katia, additional

Published
2021
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38. Iron Dyshomeostasis in COVID-19: Biomarkers Reveal a Functional Link to 5-Lipoxygenase Activation.

Author

Dufrusine, Beatrice, Valentinuzzi, Silvia, Bibbò, Sandra, Damiani, Verena, Lanuti, Paola, Pieragostino, Damiana, Del Boccio, Piero, D'Alessandro, Ersilia, Rabottini, Alberto, Berghella, Alessandro, Allocati, Nerino, Falasca, Katia, Ucciferri, Claudio, Mucedola, Francesco, Di Perna, Marco, Martino, Laura, Vecchiet, Jacopo, De Laurenzi, Vincenzo, and Dainese, Enrico

Subjects
CERULOPLASMIN, COVID-19, POST-acute COVID-19 syndrome, TRANSFERRIN, IRON metabolism, BIOMARKERS, IRON proteins
Abstract

Coronavirus disease 2019 (COVID-19) is characterized by a broad spectrum of clinical symptoms. After acute infection, some subjects develop a post-COVID-19 syndrome known as long-COVID. This study aims to recognize the molecular and functional mechanisms that occur in COVID-19 and long-COVID patients and identify useful biomarkers for the management of patients with COVID-19 and long-COVID. Here, we profiled the response to COVID-19 by performing a proteomic analysis of lymphocytes isolated from patients. We identified significant changes in proteins involved in iron metabolism using different biochemical analyses, considering ceruloplasmin (Cp), transferrin (Tf), hemopexin (HPX), lipocalin 2 (LCN2), and superoxide dismutase 1 (SOD1). Moreover, our results show an activation of 5-lipoxygenase (5-LOX) in COVID-19 and in long-COVID possibly through an iron-dependent post-translational mechanism. Furthermore, this work defines leukotriene B4 (LTB4) and lipocalin 2 (LCN2) as possible markers of COVID-19 and long-COVID and suggests novel opportunities for prevention and treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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39. BNT162b2 mRNA Vaccination Leads to Long-Term Protection from COVID-19 Disease

Author

Rossi, Claudia, primary, Lanuti, Paola, additional, Cicalini, Ilaria, additional, De Bellis, Domenico, additional, Pierdomenico, Laura, additional, Del Boccio, Piero, additional, Zucchelli, Mirco, additional, Natale, Luca, additional, Sinjari, Bruna, additional, Catitti, Giulia, additional, Vespa, Simone, additional, Simeone, Pasquale, additional, Bologna, Giuseppina, additional, Bucci, Ines, additional, Falasca, Katia, additional, Vecchiet, Jacopo, additional, Stuppia, Liborio, additional, De Laurenzi, Vincenzo, additional, and Pieragostino, Damiana, additional

Published
2021
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40. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and meta-analysis

Author

Di Mascio, Daniele, Khalil, Asma, Saccone, Gabriele, Rizzo, Giuseppe, Buca, Danilo, Liberati, Marco, Vecchiet, Jacopo, Nappi, Luigi, Scambia, Giovanni, Berghella, Vincenzo, D’Antonio, Francesco, Di Mascio, Daniele, Khalil, Asma, Saccone, Gabriele, Rizzo, Giuseppe, Buca, Danilo, Liberati, Marco, Vecchiet, Jacopo, Nappi, Luigi, Scambia, Giovanni, Berghella, Vincenzo, and D’Antonio, Francesco

Subjects
Settore MED/40
Abstract

Objective: The aim of this systematic review was to report pregnancy and perinatal outcomes of Coronavirus (CoV) spectrum infections, and particularly COVID-19 disease due to SARS-COV-2 infection during pregnancy. Data sources: Medline, Embase, Cinahl and Clinicaltrials.gov databases were searched electronically utilizing combinations of word variants for "coronavirus" or "severe acute respiratory syndrome" or "SARS" or "Middle East respiratory syndrome" or "MERS" or "COVID-19" and "pregnancy". The search and selection criteria were restricted to English language. Study eligibility criteria: Inclusion criteria were pregnant women with a confirmed Coronavirus related illness, defined as either SARS, MERS or COVID-19. Study appraisal and synthesis methods: We used meta-analyses of proportions to combine data and reported pooled proportions. The pregnancy outcomes observed included miscarriage, preterm birth, pre-eclampsia, preterm prelabor rupture of membranes, fetal growth restriction, and mode of delivery. The perinatal outcomes observed were fetal distress, Apgar score < 7 at five minutes, neonatal asphyxia, admission to neonatal intensive care unit, perinatal death, and evidence of vertical transmission. Results: 19 studies including 79 women were eligible for this systematic review: 41 pregnancies (51.9%) affected by COVID-19, 12 (15.2%) by MERS, and 26 (32.9%) by SARS. An overt diagnosis of pneumonia was made in 91.8% and the most common symptoms were fever (82.6%), cough (57.1%) and dyspnea (27.0%). For all CoV infections, the rate of miscarriage was 39.1% (95% CI 20.2-59.8); the rate of preterm birth < 37 weeks was 24.3% (95% CI 12.5-38.6); premature prelabor rupture of membranes occurred in 20.7% (95% CI 9.5-34.9), preeclampsia in 16.2% (95% CI 4.2-34.1), and fetal growth restriction in 11.7% (95% CI 3.2-24.4); 84% were delivered by cesarean; the rate of perinatal death was 11.1% (95% CI 84.8-19.6) and 57.2% (95% CI 3.6-99.8) of newborns were admitted to the neonatal intensive care unit. When focusing on COVID-19, the most common adverse pregnancy outcome was preterm birth < 37 weeks, occurring in 41.1% (95% CI 25.6-57.6) of cases, while the rate of perinatal death was 7.0% (95% CI 1.4-16.3). None of the 41 newborns assessed showed clinical signs of vertical transmission. Conclusion: In mothers infected with coronavirus infections, including COVID-19, >90% of whom also had pneumonia, PTB is the most common adverse pregnancy outcome. Miscarriage, preeclampsia, cesarean, and perinatal death (7-11%) were also more common than in the general population. There have been no published cases of clinical evidence of vertical transmission. Evidence is accumulating rapidly, so these data may need to be updated soon. The findings from this study can guide and enhance prenatal counseling of women with COVID-19 infection occurring during pregnancy.

Published
2020

45. PIDOTIMOD IN PAUCISYMPTOMATIC SARS-CoV2 INFECTED PATIENTS

Author

Ucciferri, Claudio, Barone, Mirko, Vecchiet, Jacopo, and Falasca, Katia

Subjects
Treatment, Immunomodulatory, lcsh:RC633-647.5, COVID-19, lcsh:Diseases of the blood and blood-forming organs, Safety, immunomodulatory, COVID-19, treatment, safety, Scientific Letter
Abstract

Background and purpose: Currently clinicians wide world are facing with SARS-CoV-2 pandemy, whose clinical features include fever, dry cough, fatigue and acute respiratory distress syndrome (ARDS) which can progress to life threatening sequelae. Aim of this study is to evaluate both efficacy and safety of pidotimod in paucisymptomatic SARS-CoV-2 patients without any evidence of concurrent pneumonia. Methods: Twenty SARS-CoV-2 1:1 allocated (pidotimod vs symptomatic therapy) Brescia-COVID Respiratory Severity Scale 0 patients were enrolled and complaining fever, cough without any sign of respiratory failure. None of them required standard regimens or hospitalization. Results: At two-brace cohort analysis no significant selection bias between groups were reported. In the absence of relevant drug-induced side effects or disease progression during therapy, the experimental group presented an earlier clinical resolution than the control one (Group A vs Group B: 4.10±2.18 vs 7.50±2.63 days; 95%CI: 1.13 – 5.67, SE: 1.08; p=0.006), as confirmed from a linear regression analysis. Conclusions: Pidotimod regimens in selected SARS-COV2 patients could be a viable option to induce symptoms regression, as an earlier defervescence protects from the indolent course of cytokine cascade activation. Rebalancing the immune status with pidotimod may also have prevented the evolution of the infection in patients.

Published
2020

47. Normal breathing releases SARS-CoV-2 into the air

Author

Di Carlo, Piero, primary, Falasca, Katia, additional, Ucciferri, Claudio, additional, Sinjari, Bruna, additional, Aruffo, Eleonora, additional, Antonucci, Ivana, additional, Di Serafino, Alessandra, additional, Pompilio, Arianna, additional, Damiani, Verena, additional, Mandatori, Domitilla, additional, De Fabritiis, Simone, additional, Dufrusine, Beatrice, additional, Capone, Emily, additional, Chiacchiaretta, Piero, additional, Brune, William H., additional, Di Bonaventura, Giovanni, additional, and Vecchiet, Jacopo, additional

Published
2021
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49. WED-203 - Stable temporal trend of HDV seroprevalence in central Italy across the last two decades with the circulation of HDV sub-genotypes 1 inducing different inflammatory stimuli

Author

Piermatteo, Lorenzo, Salpini, Romina, Torre, Giulia, D’Anna, Stefano, Khan, Sohaib, Duca, Leonardo, Bertoli, Ada, Malagnino, Vincenzo, Di Traglia, Loide, Paba, Pierpaolo, Ciotti, Marco, Lenci, Ilaria, Francioso, Simona, Pasquazzi, Caterina, Lichtner, Miriam, Mastroianni, Claudio M., Santopaolo, Francesco, De Sanctis, Giuseppe Maria, Marignani, Massimo, Pellicelli, Adriano, Galati, Giovanni, Moretti, Alessandra, Casinelli, Katia, Caterini, Luciano, Iapadre, Nerio, Parruti, Giustino, Vecchiet, Jacopo, Maurizio, Paoloni, Grelli, Sandro, Silberstein, Francesca Ceccherini, Sarmati, Loredana, and Svicher, Valentina

Published
2023
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