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Cutaneous melanoma is a neoplasm originating from melanocytes. In equines, a variable incidence of 6 to 14% of the total tegumentary neoplasms. The occurrence of metastasis is uncommon. In this sense, the objective was to describe a case of metastatic cutaneous melanoma in the equine species. A 15-year-old mixed-breed mare, died and was sent to perform necroscopic examination. During the processing of samples of various tissues and organs submitted to histopathological analysis. The main macroscopic alterations observed corresponded to proliferations in cutaneous glandular tissue of the udder, mammary lymph nodes, heart, lung, parietal pleura, liver and spleen, with sometimes blackened cutting surface. The morphological pattern, throughout the udder tissue extension, was compatible with melanoma. Histopathological evaluation of the two affected organs revealed a similar microscopic appearance. When associating the anatomopathological findings, a picture of metastatic cutaneous melanoma was defined. Melanoma should be considered as one of the possible diseases that affect the integument wrapping of the udder of mares of advanced age. A thorough evaluation of the animal is useful, since the metastatic potential is a real possibility.

This study evaluated the effects of varying amounts of melon with high sugar content offered to sheep without prior melon experience and that were not adapted to consuming it. We used 12 eight-month-old, rumen-cannulated crossbred sheep weighing 25 kg each. The animals received a base diet of roughage, and then half were randomly selected to have 25% of their diet replaced with melon (G25%) and the other half had 75% of their diet replaced with melon (75%). Ruminal fluid was collected before administration of melon and at 0, 3, 6, 12, 18, and 24 h after the administration of the fruit. Sheep from the G25% group presented volatile fatty acid ruminal acidosis (sub-acute) between 3 and 6 h after consumption. This acidosis was characterized by a rumen pH slightly lower than 5.6, increased discrete L-lactic acid content, and increased redox potential (RP) and methylene blue redox (MBR) time of the ruminal fluid. The G75% group presented lactic ruminal acidosis at T6h, characterized by a rumen pH lower than 5.0, high lactate-L content, increased RP and MBR time, and increased ruminal fluid osmolarity. Therefore, offering large amounts of melon (75% of dry matter (DM)) is not recommended but 25% of DM of this fruit can be used safely. Resumo: O presente estudo avaliou o efeito da adição à dieta de duas diferentes quantidades de melão com alto teor de açucares oferecidos subitamente à ovinos não adaptados. Foram utilizados 12 ovinos mestiços da raça Santa Inês, com 8 meses de idade e pesando cerca der 25 kg providos de cânula ruminal. Os animais recebiam dieta à base de volumoso e foram aleatoriamente divididos em dois grupos iguais que receberam 25 ou 75% de adição de melão picado à dieta. Foram coletadas amostras de conteúdo ruminal nos momentos zero e após 3, 6, 12, 18, e 24 horas da administração do melão. Ovinos do grupo G25% apresentaram acidose por ácido graxo voláteis (subaguda) entre 3 e 6 horas, caracterizada por pH ruminal ligeiramente abaixo de 5,6, aumento discreto na concentração de ácido láctico L e aumento do potencial redox (PR) e tempo de redução do azul de metileno (TRAM) do fluido ruminal. O grupo G75% apresentou acidose láctica ruminal com pH menor que 5,0, alta concentração de Lactato-L e aumento do PR e TRAM e da osmolaridade ruminal. Em conclusão, o oferecimento de grandes quantidades de melão (75% da MS) não é recomendado, mas 25% da MS desta fruta pode ser utilizada na dieta de ovinos com segurança.

Made available in DSpace on 2016-08-15T20:31:32Z (GMT). No. of bitstreams: 1 RodolfoGV_DISSERT.pdf: 1093559 bytes, checksum: ab9bf9b53ab3a3bbbaa384e5660f820f (MD5) Previous issue date: 2015-07-31 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Creation of goats has an important socio-economic role in the Northeast, concentrating more than 90% of the national herd. This limited activity in this region is for the seasonal rainy period short and low rainfall intensity; restricting the forage supply along the year and favoring the appearance of deficiency and metabolic diseases. This fact stresses the need for seasonality effects of study on energy and protein profile goats extensively created any semiarid Rio Grande do Norte. Were used 20 goats without defined standard racial, male, neutered, healthy, kept two properties, separated into two groups of 10 animals, during 12 months. The blood was collected monthly paragraph rating protein (total protein, albumin and urea) and energy (betahydroxybutyrate, fatty acids esterified not, glucose and cholesterol). Following the reference values literature consulted none of the above variables showed superior values. Among variables such as protein albumin, a protein total, urea values critics had no definite dry period. In the energy assessment, during the rainy season, glucose and cholesterol values showed minor, while the beta-hydroxybutyrate and esterified fatty acids presented no more values indicating the energy deficit especially in this season of the year. That way we can infer the need for energy supplementation no rainy period and protein do not definite dry period, paragraph goats extensive created a non semiarid Northeast A criação de caprinos tem um importante papel socioeconômico na região Nordeste, concentrando a maior parte do rebanho nacional. Esta atividade está limitada nessa região pela sazonalidade do período chuvoso curto e de baixa intensidade pluviométrica; restringindo o suprimento forrageiro ao longo do ano e favorecendo o aparecimento de doenças carenciais e metabólicas. Esse fato releva a necessidade do estudo dos efeitos da sazonalidade sobre o perfil energético e proteico de caprinos criados extensivamente no semiárido do Rio Grande do Norte. Foram utilizados 20 caprinos sem padrão racial definido, machos, castrados, hígidos, mantidos em duas propriedades, sendo 10 animais em cada, durante 12 meses. O sangue foi coletado mensalmente para avaliação proteica (proteína total, albumina e ureia) e energética (beta-hidroxibutirato, ácidos graxos não esterificados, glicose e colesterol). Dentre as variáveis proteicas: albumina, ureia e proteína total apresentaram déficit tanto no período chuvoso quanto no final do período seco. Já na avaliação energética: glicose e colesterol apresentaram valores menores, enquanto beta-hidroxibutirato e ácidos graxos não esterificados apresentaram valores maiores, indicando o déficit energético na época chuvosa. O perfil metabólico determinado mostrou a necessidade de suplementação energética e proteica no período chuvoso, e apenas de proteína no final do período seco para caprinos criados extensivamente no semiárido do Rio Grande do Norte