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3. The Prognostic Value of Troponin-T in Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation: A COACT Substudy

Author

Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van der Pas, Stéphanie, and van Royen, Niels

Published
2024
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5. Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study

Author

Abrough, Fekri, Acharya, Subhash P, Amin, Pravin, Arabi, Yaseen, Aragao, Irene, Bauer, Philippe, Beduneau, Gaëtan, Beitler, Jeremy, Berkius, Johan, Bugedo, Guillermo, Camporota, Luigi, Cerny, Vladimir, Cho, Young-Jae, Clarkson, Kevin, Estenssoro, Elisa, Goligher, Ewan, Grasselli, Giacomo, Gritsan, Alexey, Hashemian, Seyed Mohammadreza, Hermans, Greet, Heunks, Leo M, Jovanovic, Bojan, Kurahashi, Kiyoyasu, Laake, Jon Henrik, Matamis, Dimitrios, Moerer, Onnen, Molnar, Zsolt, Ozyilmaz, Ezgi, Panka, Bernardo, Papali, Alfred, Peñuelas, Óscar, Perbet, Sébastien, Piquilloud, Lise, Qiu, Haibo, Razek, Assem Abdel, Rittayamai, Nuttapol, Roldan, Rollin, Serpa Neto, Ary, Szuldrzynski, Konstanty, Talmor, Daniel, Tomescu, Dana, Van Haren, Frank, Villagomez, Asisclo, Zeggwagh, Amine Ali, Abe, Toshikazu, Aboshady, Abdelrhman, Acampo-de Jong, Melanie, Acharya, Subhash, Adderley, Jane, Adiguzel, Nalan, Agrawal, Vijay Kumar, Aguilar, Gerardo, Aguirre, Gaston, Aguirre-Bermeo, Hernan, Ahlström, Björn, Akbas, Türkay, Akker, Mustafa, Al Sadeh, Ghamdan, Alamri, Sultan, Algaba, Angela, Ali, Muneeb, Aliberti, Anna, Allegue, Jose Manuel, Alvarez, Diana, Amador, Joaquin, Andersen, Finn H, Ansari, Sharique, Apichatbutr, Yutthana, Apostolopoulou, Olympia, Arellano, Daniel, Arica, Mestanza, Arikan, Huseyin, Arinaga, Koichi, Arnal, Jean-Michel, Asano, Kengo, Asín-Corrochano, Marta, Avalos Cabrera, Jesus Milagrito, Avila Fuentes, Silvia, Aydemir, Semih, Aygencel, Gulbin, Azevedo, Luciano, Bacakoglu, Feza, Badie, Julio, Baedorf Kassis, Elias, Bai, Gabriela, Balaraj, Govindan, Ballico, Bruno, Banner-Goodspeed, Valerie, Banwarie, Preveen, Barbieri, Rosella, Baronia, Arvind, Barrett, Jonathan, Barrot, Loïc, Barrueco-Francioni, Jesus Emilio, Barry, Jeffrey, Bawangade, Harshal, Beavis, Sarah, Beck, Eduardo, Beehre, Nina, Belenguer Muncharaz, Alberto, Bellani, Giacomo, Belliato, Mirko, Bellissima, Agrippino, Beltramelli, Rodrigo, Ben Souissi, Asma, Benitez-Cano, Adela, Benlamin, Mohamed, Benslama, Abdellatif, Bento, Luis, Benvenuti, Daniela, Bernabe, Laura, Bersten, Andrew, Berta, Giacomo, Bertini, Pietro, Bertram-Ralph, Elliot, Besbes, Mohamed, Bettini, Lisandro Roberto, Beuret, Pascal, Bewley, Jeremy, Bezzi, Marco, Bhakhtiani, Lakshay, Bhandary, Rakesh, Bhowmick, Kaushik, Bihari, Shailesh, Bissett, Bernie, Blythe, David, Bocher, Simon, Boedjawan, Narain, Bojanowski, Christine M, Boni, Elisa, Boraso, Sabrina, Borelli, Massimo, Borello, Silvina, Borislavova, Margarita, Bosma, Karen J, Bottiroli, Maurizio, Boyd, Owen, Bozbay, Suha, Briva, Arturo, Brochard, Laurent, Bruel, Cédric, Bruni, Andrea, Buehner, Ulrike, Bulpa, Pierre, Burt, Karen, Buscot, Mathieu, Buttera, Stefania, Cabrera, Jorge, Caccese, Roberta, Caironi, Pietro, Canchos Gutierrez, Ivan, Canedo, Nancy, Cani, Alma, Cappellini, Iacopo, Carazo, Jesus, Cardonnet, Luis Pablo, Carpio, David, Carriedo, Demetrio, Carrillo, Ramón, Carvalho, João, Caser, Eliana, Castelli, Antonio, Castillo Quintero, Manuel, Castro, Heloisa, Catorze, Nuno, Cengiz, Melike, Cereijo, Enrique, Ceunen, Helga, Chaintoutis, Christos, Chang, Youjin, Chaparro, Gustavogcha, Chapman, Carmel, Chau, Simon, Chavez, Cecilia Eugenia, Chelazzi, Cosimo, Chelly, Jonathan, Chemouni, Frank, Chen, Kai, Chena, Ariel, Chiarandini, Paolo, Chilton, Phil, Chiumello, Davide, Chou-Lie, Yvette, Chudeau, Nicolas, Cinel, Ismail, Cinnella, Gilda, Clark, Michele, Clark, Thomas, Clementi, Stefano, Coaguila, Luis, Codecido, Alexis Jaspe, Collins, Amy, Colombo, Riccardo, Conde, Juan, Consales, Guglielmo, Cook, Tim, Coppadoro, Andrea, Cornejo, Rodrigo, Cortegiani, Andrea, Coxo, Cristina, Cracchiolo, Andrea Neville, Crespo Ramirez, Mónica, Crova, Philippe, Cruz, José, Cubattoli, Lucia, Çukurova, Zafer, Curto, Francesco, Czempik, Piotr, D'Andrea, Rocco, da Silva Ramos, Fernando, Dangers, Laurence, Danguy des Déserts, Marc, Danin, Pierre-Eric, Dantas, Fabianne, Daubin, Cédric, Dawei, Wu, de Haro, Candelaria, de Jesus Montelongo, Felipe, De Mendoza, Diego, de Pablo, Raúl, De Pascale, Gennaro, De Rosa, Silvia, Decavèle, Maxens, Declercq, Pierre-Louis, Deicas, Alberto, del Carmen Campos Moreno, María, Dellamonica, Jean, Delmas, Benjamin, Demirkiran, Oktay, Demirkiran, Hilmi, Dendane, Tarek, di Mussi, Rossella, Diakaki, Chrysi, Diaz, Anatilde, Diaz, Willy, Dikmen, Yalim, Dimoula, Aikaterini, Doble, Patricia, Doha, Nagwa, Domingos, Guilherme, Dres, Martin, Dries, David, Duggal, Abhijit, Duke, Graeme, Dunts, Pavel, Dybwik, Knut, Dykyy, Maksym, Eckert, Philippe, Efe, Serdar, Elatrous, Souheil, Elay, Gülseren, Elmaryul, Abubaker S, Elsaadany, Mohamed, Elsayed, Hany, Elsayed, Samar, Emery, Malo, Ena, Sébastien, Eng, Kevin, Englert, Joshua A, Erdogan, Elif, Ergin Ozcan, Perihan, Eroglu, Ege, Escobar, Miguel, Esen, Figen, Esen Tekeli, Arzu, Esquivel, Alejandro, Esquivel Gallegos, Helbert, Ezzouine, Hanane, Facchini, Alberto, Faheem, Mohammad, Fanelli, Vito, Farina, Maria Fernanda, Fartoukh, Muriel, Fehrle, Lutz, Feng, Feng, Feng, Yufeng, Fernandez, Irene, Fernandez, Borja, Fernandez-Rodriguez, Maria Lorena, Ferrando, Carlos, Ferreira da Silva, Maria João, Ferreruela, Mireia, Ferrier, Janet, Flamm Zamorano, Matias Jesús, Flood, Laura, Floris, Leda, Fluckiger, Martin, Forteza, Catalina, Fortunato, Antonella, Frans, Eric, Frattari, Antonella, Fredes, Sebastian, Frenzel, Tim, Fumagalli, Roberto, Furche, Mariano Andres, Fusari, Maurizio, Fysh, Edward, Galeas-Lopez, Juan Luis, Galerneau, Louis-Marie, Garcia, Analía, Garcia, María Fernanda, Garcia, Elisabet, Garcia Olivares, Pablo, Garlicki, Jaroslaw, Garnero, Aude, Garofalo, Eugenio, Gautam, Prabha, Gazenkampf, Andrey, Gelinotte, Stéphanie, Gelormini, Domenico, Ghrenassia, Etienne, Giacomucci, Angelo, Giannoni, Robert, Gigante, Andrea, Glober, Nancy, Gnesin, Paolo, Gollo, Yari, Gomaa, Dina, Gomero Paredes, Rosita, Gomes, Rui, Gomez, Raúl Alejandro, Gomez, Oscar, Gomez, Aroa, Gondim, Louise, Gonzalez, Manuel, Gonzalez, Isabel, Gonzalez-Castro, Alejandro, Gordillo Romero, Orlando, Gordo, Federico, Gouin, Philippe, Graf Santos, Jerónimo, Grainne, Rooney, Grando, Matilde, Granov Grabovica, Sanja, Grasso, Salvatore, Grasso, Rinaldo, Grimmer, Lisa, Grissom, Colin, Gu, Qing, Guan, Xiang-Dong, Guarracino, Fabio, Guasch, Neus, Guatteri, Luca, Gueret, Renaud, Guérin, Claude, Guerot, Emmanuel, Guitard, Pierre-Gildas, Gül, Fethi, Gumus, Ayca, Gurjar, Mohan, Gutierrez, Patricia, Hachimi, Abdelhamid, Hadzibegovic, Adi, Hagan, Samantha, Hammel, Clare, Han Song, Joo, Hanlon, Gabrielle, Heines, Serge, Henriksson, Johanna, Herbrecht, Jean-Etienne, Heredia Orbegoso, Gabriel Omar, Hermon, Andrew, Hernandez, Rosana, Hernandez, Carmen, Herrera, Luis, Herrera-Gutierrez, Manuel, Heunks, Leo, Hidalgo, Juan, Hill, Dianne, Holmquist, Dagmar, Homez, Marcela, Hongtao, Xia, Hormis, Anil, Horner, Daniel, Hornos, M Carmen, Hou, Meihong, House, Stacy, Housni, Brahim, Hugill, Keith, Humphreys, Sally, Humbert, Louis, Hunter, Stephanie, Hwa Young, Lee, Iezzi, Nicolas, Ilutovich, Santiago, Inal, Volkan, Innes, Richard, Ioannides, Panagiotis, Iotti, Giorgio Antonio, Ippolito, Mariachiara, Irie, Hiromasa, Iriyama, Hiroki, Itagaki, Taiga, Izura, Javier, Izza, Santiago, Jabeen, Rakhshanda, Jamaati, Hamidreza, Jamadarkhana, Sunil, Jamoussi, Amira, Jankowski, Milosz, Jaramillo, Luis Alberto, Jeon, Kyeongman, Jeong Lee, Seok, Jeswani, Deepak, Jha, Simant, Jiang, Liangyan, Jing, Chen, Jochmans, Sébastien, Johnstad, Bror Anders, Jongmin, Lee, Joret, Aurélie, Junhasavasdikul, Detajin, Jurado, Maria Teresa, Kam, Elisa, Kamohara, Hidenobu, Kane, Caroline, Kara, Iskender, Karakurt, Sait, Karnjanarachata, Cherdkiat, Kataoka, Jun, Katayama, Shinshu, Kaushik, Shuchi, Kelebek Girgin, Nermin, Kerr, Kathryn, Kerslake, Ian, Khairnar, Prakash, Khalid, Abidi, Khan, Akram, Khanna, Ashish K, Khorasanee, Reza, Kienhorst, Dieneke, Kirakli, Cenk, Knafelj, Rihard, Kol, Mark Kol, Kongpolprom, Napplika, Kopitko, Csaba, Korkmaz Ekren, Pervin, Kubisz-Pudelko, Agnieszka, Kulcsar, Zoltan, Kumasawa, Junji, Kuriyama, Akira, Kutchak, Fernanda, Labarca, Eduardo, Labat, Françoise, Laborda, César, Laca Barrera, Manuel Alberto, Lagache, Laurie, Landaverde Lopez, Antonio, Lanspa, Michael, Lascari, Valeria, Le Meur, Matthieu, Lee, Su Hwan, Lee, Young Ju, Lee, Jinwoo, Lee, Won-Yeon, Lee, Jarone, Legernaes, Terje, Leiner, Tamaas, Lemiale, Virginie, Leonor, Tiago, Lepper, Philipp M, Li, Dahuan, Li, Hongbin, Li, Oleg, Lima, Ana Raquel, Lind, Dan, Litton, Edward, Liu, Ning, Liu, Ling, Liu, Jialin, Llitjos, Jean-François, Llorente, Beatriz, Lopez, Rodolfo, Lopez, Claudia Elizabeth, Lopez Nava, Claudia, Lovazzano, Pablo, Lu, Min, Lucchese, Francesca, Lugano, Manuela, Lugo Goytia, Gustavo, Luo, Hua, Lynch, Ceri, Macheda, Sebastiano, Madrigal Robles, Victor Hugo, Maggiore, Salvatore Maurizio, Magret Iglesias, Mònica, Malaga, Peter, Mallapura Maheswarappa, Harish, Malpartida, Guillermo, Malyarchikov, Andrey, Mansson, Helena, Manzano, Anaid, Marey, Ismael, Marin, Nathalie, Marin, Maria del Carmen, Markman, Eliana, Martin, Felix, Martin, Alex, Martin Dal Gesso, Cristina, Martinez, Felipe, Martínez-Fidalgo, Conchita, Martin-Loeches, Ignacio, Mas, Arantxa, Masaaki, Sakuraya, Maseda, Emilio, Massa, Eleni, Mattsson, Anna, Maugeri, Jessica, McCredie, Victoria, McCullough, James, McGuinness, Shay, McKown, Andrew, Medve, László, Mei, Chengqing, Mellado Artigas, Ricard, Mendes, Vitor, Mervat, Mohamed Khalaf Ebraheim, Michaux, Isabelle, Mikhaeil, Michael, Milagros, Olga, Milet, Igor, Millan, Maria Teresa, Minwei, Zhang, Mirabella, Lucia, Mishra, Sanghamitra, Mistraletti, Giovanni, Mochizuki, Katsunori, Moghal, Arif, Mojoli, Francesco, Molin, Alexandre, Montiel, Raquel, Montini, Luca, Monza, Gianmario, Mora Aznar, Maria, Morakul, Sunthiti, Morales, Maria, Moreno Torres, Daniel, Morocho Tutillo, Diego Rolando, Motherway, Catherine, Mouhssine, Doumiri, Mouloudi, Eleni, Muñoz, Tapia, Munoz de Cabo, Carlos, Mustafa, Mohamed, Muthuchellappan, Radhakrishnan, Muthukrishnan, Muraleekrishnan, Muttini, Stefano, Nagata, Isao, Nahar, Dick, Nakanishi, Misuzu, Nakayama, Izumi, Namendys-Silva, Silvio Antonio, Nanchal, Rahul, Nandakumar, Sivakumar, Nasi, Alessandra, Nasir, Kamal, Navalesi, Paolo, Naz Aslam, Tayyba, Nga Phan, Thuy, Nichol, Alistair, Niiyama, Shuhei, Nikolakopoulou, Sofia, Nikolic, Elena, Nitta, Kenichi, Noc, Marko, Nonas, Stephanie, Nseir, Saad, Nur Soyturk, Ayse, Obata, Yukako, Oeckler, Richard, Oguchi, Moe, Ohshimo, Shinichiro, Oikonomou, Marina, Ojados, Agueda, Oliveira, Maria Teresa, Oliveira Filho, Wilson, Oliveri, Carlo, Olmos, Aitor, Omura, Kazuya, Orlandi, Maria Cristina, Orsenigo, Francesca, Ortiz-Ruiz De Gordoa, Laura, Ota, Kei, Ovalle Olmos, Rainier, Öveges, Nándo, Oziemski, Peter, Ozkan Kuscu, Ozlem, Pachas Alvarado, Fernando, Pagella, Gonzalo, Palaniswamy, Vijayanand, Palazon Sanchez, Eugenio Luis, Palmese, Salvatore, Pan, Guojun, Pan, Wensen, Papanikolaou, Metaxia, Papavasilopoulou, Theonymfi, Parekh, Ameet, Parke, Rachael, Parrilla, Francisco J, Parrilla, Dácil, Pasha, Taha, Pasin, Laura, Patão, Luis, Patel, Mayur, Patel, Grisma, Pati, Basanta Kumar, Patil, Jayaprakash, Pattnaik, Saroj, Paul, Daniel, Pavesi, Maurizio, Pavlotsky, Vanesa Alejandra, Paz, Graciela, Paz, Enrique, Pecci, Elisabetta, Pellegrini, Carlos, Peña Padilla, Andrea Gabriela, Perchiazzi, Gaetano, Pereira, Tiago, Pereira, Vera, Perez, Manuel, Perez Calvo, Cesar, Perez Cheng, Meisy, Perez Maita, Ronald, Pérez-Araos, Rodrigo, Perez-Teran, Purificación, Perez-Torres, David, Perkins, Gavin, Persona, Paolo, Petnak, Tananchai, Petrova, Marina, Pham, Tai, Philippart, François, Picetti, Edoardo, Pierucci, Elisabetta, Piervincenzi, Edoardo, Pinciroli, Riccardo, Pintado, Maria-Consuelo, Piraino, Thomas, Piras, Stephanie, Piras, Claudio, Pirompanich, Pattarin, Pisani, Luigi, Platas, Enrique, Plotnikow, Gustavo, Porras, Willy, Porta, Virginia, Portilla, Mariana, Portugal, José, Povoa, Pedro, Prat, Gwenael, Pratto, Romina, Preda, Gabriel, Prieto, Isidro, Prol-Silva, Estefania, Pugh, Richard, Qi, Yupeng, Qian, Chuanyun, Qin, Tiehe, Qu, Hongping, Quintana, Teobaldo, Quispe Sierra, Rosari, Quispe Soto, Rocio, Rabbani, Raihan, Rabee, Mohamed, Rabie, Ahmed, Rahe Pereira, Maria Augusta, Rai, Ashish, Raj Ashok, Sundar, Rajab, Mostafa, Ramdhani, Navin, Ramey, Elizabeth, Ranieri, Marco, Rathod, Darshana, Ray, Banambar, Redwanul Huq, Shihan Mahmud, Regli, Adrian, Reina, Rosa, Resano Sarmiento, Natalia, Reynaud, Faustine, Rialp, Gemma, Ricart, Pilar, Rice, Todd, Richardson, Angus, Rieder, Marcelo, Rinket, Martin, Rios, Fernando, Risso Vazquez, Alejandro, Riva, Ivano, Rivette, Monaly, Roca, Oriol, Roche-Campo, Ferran, Rodriguez, Covadonga, Rodriguez, Gabriel, Rodriguez Gonzalez, Daniel, Rodriguez Tucto, Xandra Yanina, Rogers, Angela, Romano, María Elena, Rørtveit, Linda, Rose, Alastair, Roux, Damien, Rouze, Anahita, Rubatto Birri, Paolo Nahuel, Ruilan, Wang, Ruiz Robledo, Aldana, Ruiz-Aguilar, Antonio Luis, Sadahiro, Tomohito, Saez, Ignacio, Sagardia, Judith, Saha, Rajnish, Saha, Rohit, Saiphoklang, Narongkorn, Saito, Shigeki, Salem, Maie, Sales, Gabriele, Salgado, Patricia, Samavedam, Srinivas, Sami Mebazaa, Mhamed, Samuelsson, Line, San Juan Roman, Nandyelly, Sanchez, Patricia, Sanchez-Ballesteros, Jesus, Sandoval, Yazcitk, Sani, Emanuele, Santos, Martin, Santos, Carla, Sanui, Masamitsu, Saravanabavan, Lakshmikanthcharan, Sari, Sema, Sarkany, Agnes, Sauneuf, Bertrand, Savioli, Monica, Sazak, Hilal, Scano, Riccardo, Schneider, Francis, Schortgen, Frédérique, Schultz, Marcus J, Schwarz, Gabriele Leonie, Seçkin Yücesoy, Faruk, Seely, Andrew, Seiler, Frederik, Seker Tekdos, Yasemin, Seok Chan, Kim, Serano, Luca, Serednicki, Wojciech, Setten, Mariano, Shah, Asim, Shah, Bhagyesh, Shang, You, Shanmugasundaram, Pradeep, Shapovalov, Konstantin, Shebl, Eman, Shiga, Takuya, Shime, Nobuaki, Shin, Phil, Short, Jack, Shuhua, Chen, Siddiqui, Sughrat, Silesky Jimenez, Juan Ignacio, Silva, Daniel, Silva Sales, Betania, Simons, Koen, Sjøbø, Brit Ågot, Slessor, David, Smiechowicz, Jakub, Smischney, Nathan, Smith, Paul, Smith, Tim, Smith, Mark, Snape, Sarah, Snyman, Lindi, Soetens, Filiep, Sook Hong, Kyung, Sosa Medellin, Miguel Ángel, Soto, Giovanna, Souloy, Xavier, Sousa, Elsa, Sovatzis, Stefania, Sozutek, Didem, Spadaro, Savino, Spagnoli, Marco, Spångfors, Martin, Spittle, Nick, Spivey, Mike, Stapleton, Andrew, Stefanovic, Branislava, Stephenson, Lorraine, Stevenson, Elizabeth, Strand, Kristian, Strano, Maria Teresa, Straus, Slavenka, Sun, Chenliang, Sun, Rongqing, Sundaram, Venkat, SunPark, Tai, Surlemont, Elisabeth, Sutherasan, Yuda, Szabo, Zsuzsanna, Tainter, Christopher, Takaba, Akihiro, Tallott, Mandy, Tamasato, Tamasato, Tang, Zhanhong, Tangsujaritvijit, Viratch, Taniguchi, Leandro, Taniguchi, Daisuke, Tarantino, Fabio, Teerapuncharoen, Krittika, Temprano, Susana, Terragni, Pierpaolo, Terzi, Nicolas, Thakur, Anand, Theerawit, Pongdhep, Thille, Arnaud W, Thomas, Matt, Thungtitigul, Poungrat, Thyrault, Martial, Tilouch, Nejla, Timenetsky, Karina, Tirapu, Juna, Todeschini, Manuel, Tomas, Roser, Tomaszewski, Christian, Tonetti, Tommaso, Tonnelier, Alexandre, Trinder, John, Trongtrakul, Konlawij, Truwit, Jonathon, Tsuei, Betty, Tulaimat, Aiman, Turan, Sema, Turkoglu, Melda, Tyagi, Sanjeev, Ubeda, Alejandro, Vagginelli, Federica, Valenti, María Florencia, Vallverdu, Imma, Van Axel, Alisha, van den Hul, Ingrid, van der Hoeven, Hans, Van Der Meer, Nardo, Vanhoof, Marc, Vargas-Ordoñez, Mónica, Vaschetto, Rosanna, Vascotto, Ettore, Vatsik, Maria, Vaz, Ana, Vazquez-Sanchez, Antonia, Ventura, Sara, Vermeijden, Jan Wytze, Vidal, Anxela, Vieira, Jocyelle, Vilela Costa Pinto, Bruno, Villagra, Ana, Villegas Succar, Cristina, Vinorum, Ole Georg, Vitale, Giovanni, Vj, Ramesh, Vochin, Ana, Voiriot, Guillaume, Volta, Carlo Alberto, von Seth, Magnus, Wajdi, Maazouzi, Walsh, Don, Wang, Shouhong, Wardi, Gabriel, Ween-Velken, Nils Christian, Wei, Bi-Lin, Weller, Dolf, Welsh, Deborah, Welters, Ingeborg, Wert, Michael, Whiteley, Simon, Wilby, Elizabeth, Williams, Erin, Williams, Karen, Wilson, Antoinette, Wojtas, Jadwiga, Won Huh, Jin, Wrathall, David, Wright, Christopher, Wu, Jian-Feng, Xi, Guo, Xing, Zheng-Jiang, Xu, Hongyang, Yamamoto, Kotaro, Yan, Jie, Yáñez, Julio, Yang, Xiaobo, Yates, Elliot, Yazicioglu Mocin, Ozlem, Ye, Zhenglong, Yildirim, Fatma, Yoshida, Norifumi, Yoshido, Hector Higo Leon, Young Lee, Bo, Yu, Rongguo, Yu, Gong, Yu, Tao, Yuan, Boyun, Yuangtrakul, Nadwipa, Yumoto, Tetsuya, Yun, Xie, Zakalik, Graciela, Zaki, Ahmad, Zalba-Etayo, Begoña, Zambon, Massimo, Zang, Bin, Zani, Gianluca, Zarka, Jonathan, Zerbi, Simone Maria, Zerman, Avsar, Zetterquist, Harald, Zhang, Jiuzhi, Zhang, Hongwen, Zhang, Wei, Zhang, Guoxiu, Zhang, Weixin, Zhao, Hongsheng, Zheng, Jia, Zhu, Bin, Zumaran, Ronald, Pham, Tài, Madotto, Fabiana, Goligher, Ewan C, Mancebo, Jordi, Peñuelas, Oscar, Pesenti, Antonio, Wunsch, Hannah, van Haren, Frank, and Laffey, John G

Published
2023
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10. The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial

Author

Lemkes, Jorrit S., Spoormans, Eva M., Demirkiran, Ahmet, Leutscher, Sophie, Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Rémon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Jessurun, Gillian A.J., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van de Ven, Peter M., van Loon, Ramon B., and van Royen, Niels

Published
2021
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12. Sex differences in patients with out-of-hospital cardiac arrest without ST-segment elevation: A COACT trial substudy

Author

Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., van de Ven, Peter M., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., der Harst, Pim van, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Jessurun, Gillian A.J., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., Appelman, Yolande, and van Royen, Niels

Published
2021
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13. Rationale and design of the PRAETORIAN-COVID trial: A double-blind, placebo-controlled randomized clinical trial with valsartan for PRevention of Acute rEspiraTORy dIstress syndrome in hospitAlized patieNts with SARS-COV-2 Infection Disease

Author

Gommans, D. H. Frank, Nas, Joris, Pinto-Sietsma, Sara-Joan, Koop, Yvonne, Konst, Regina E., Mensink, Frans, Aarts, Goaris W.A., Konijnenberg, Lara S.F., Cortenbach, Kimberley, Verhaert, Dominique V.M., Thannhauser, Jos, Mol, Jan-Quinten, Rooijakkers, Maxim J.P., Vos, Jacqueline L., van Rumund, Anouke, Vart, Priya, Hassing, Robert-Jan, Cornel, Jan-Hein, de Jager, C. Peter C., van den Heuvel, Michel M., van der Hoeven, Hans G., Verbon, Annelies, Pinto, Yigal M., van Royen, Niels, van Kimmenade, Roland R.J., de Leeuw, Peter W., van Agtmael, Michiel A., Bresser, Paul, van Gilst, Wiek H., Vonk-Noordergraaf, Anton, and Tijssen, Jan G.P.

Published
2020
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16. COVID-19: 10 things I wished I'd known some months ago

Author

Pickkers, Peter, van der Hoeven, Hans, and Citerio, Giuseppe

Subjects
Hospital patients, Medical centers, Communicable diseases, COVID-19, Medical schools, Medical colleges
Abstract

Author(s): Peter Pickkers [sup.1] [sup.2], Hans van der Hoeven [sup.1] [sup.2], Giuseppe Citerio [sup.3] Author Affiliations: (1) grid.10417.33, 0000 0004 0444 9382, Department of Intensive Care Medicine, Radboud University Medical [...]

Published
2020
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17. The Prognostic Value of Troponin-T in Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation:A COACT Substudy

Author

Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van der Pas, Stéphanie, van Royen, Niels, Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van der Pas, Stéphanie, and van Royen, Niels

Abstract

Background: In out-of-hospital cardiac arrest (OHCA) without ST-elevation, predictive markers that can identify those with a high risk of acute coronary syndrome are lacking. Methods: In this post hoc analysis of the Coronary Angiography after Cardiac Arrest (COACT) trial, the baseline, median, peak, and time-concentration curves of troponin-T (cTnT) (T-AUC) in OHCA patients without ST-elevation were studied. cTnT values were obtained at predefined time points at 0, 3, 6, 12, 24, 36, 28, and 72 hours after admission. All patients who died within the measurement period were not included. The primary outcome was the association between cTnT and 90-day survival. Secondary outcomes included the association of cTnT and acute thrombotic occlusions, acute unstable lesions, and left ventricular function. Results: In total, 352 patients were included in the analysis. The mean age was 64 ± 13 years (80.4% men). All cTnT measures were independent prognostic factors for mortality after adjustment for potential confounders age, sex, history of coronary artery disease, witnessed arrest, time to BLS, and time to return of spontaneous circulation (eg, for T-AUC: hazard ratio, 1.44; 95% CI, 1.06-1.94; P = .02; P value for all variables ≤ .02). Median cTnT (odds ratio [OR], 1.58; 95% CI, 1.18-2.12; P = .002) and T-AUC (OR, 2.03; 95% CI, 1.25-3.29; P = .004) were independent predictors for acute unstable lesions. Median cTnT (OR, 1.62; 95% CI, 1.17-2.23; P = .003) and T-AUC (OR, 2.16; 95% CI, 1.27-3.68; P = .004) were independent predictors for acute thrombotic occlusions. CTnT values were not associated with the left ventricular function (eg, for T-AUC: OR, 2.01; 95% CI, 0.65-6.19; P = .22; P value for all variables ≥ .14)Conclusion:In OHCA patients without ST-segment elevation, cTnT release during the first 72 hours after return of spontaneous circulation was associated with clinical outcomes.

Published
2024

18. The Prognostic Value of Troponin-T in Out-of-Hospital Cardiac Arrest Without ST-Segment Elevation: A COACT Substudy

Author

Cardiologie, Team Medisch, Gezonde Vaten, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van der Pas, Stéphanie, van Royen, Niels, Cardiologie, Team Medisch, Gezonde Vaten, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M., Lemkes, Jorrit S., Janssens, Gladys N., van der Hoeven, Nina W., Jewbali, Lucia S.D., Dubois, Eric A., Meuwissen, Martijn, Rijpstra, Tom A., Bosker, Hans A., Blans, Michiel J., Bleeker, Gabe B., Baak, Remon, Vlachojannis, Georgios J., Eikemans, Bob J.W., van der Harst, Pim, van der Horst, Iwan C.C., Voskuil, Michiel, van der Heijden, Joris J., Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P., Vlaar, Alexander P.J., Vink, Maarten A., van den Bogaard, Bas, Heestermans, Ton A.C.M., de Ruijter, Wouter, Delnoij, Thijs S.R., Crijns, Harry J.G.M., Oemrawsingh, Pranobe V., Gosselink, Marcel T.M., Plomp, Koos, Magro, Michael, Elbers, Paul W.G., van der Pas, Stéphanie, and van Royen, Niels

Published
2024

22. Effects of levosimendan on respiratory muscle function in patients weaning from mechanical ventilation

Author

Roesthuis, Lisanne, van der Hoeven, Hans, Sinderby, Christer, Frenzel, Tim, Ottenheijm, Coen, Brochard, Laurent, and Doorduin, Jonne

Subjects
Analysis, Research, Medical research -- Analysis, Continuous positive airway pressure -- Analysis -- Research, Drug approval -- Research -- Analysis, Medicine, Experimental -- Analysis
Abstract

Author(s): Lisanne Roesthuis [sup.1], Hans van der Hoeven [sup.1], Christer Sinderby [sup.2] [sup.3] [sup.4], Tim Frenzel [sup.1], Coen Ottenheijm [sup.5] [sup.6], Laurent Brochard [sup.2] [sup.7], Jonne Doorduin [sup.8], Leo Heunks [...], Purpose Respiratory muscle weakness frequently develops in critically ill patients and is associated with adverse outcome, including difficult weaning from mechanical ventilation. Today, no drug is approved to improve respiratory muscle function in these patients. Previously, we have shown that the calcium sensitizer levosimendan improves calcium sensitivity of human diaphragm muscle fibers in vitro and contractile efficiency of the diaphragm in healthy subjects. The main purpose of this study is to investigate the effects of levosimendan on diaphragm contractile efficiency in mechanically ventilated patients. Methods In a double-blind randomized placebo-controlled trial, mechanically ventilated patients performed two 30-min continuous positive airway pressure (CPAP) trials with 5-h interval. After the first CPAP trial, study medication (levosimendan 0.2 [micro]g/kg/min continuous infusion or placebo) was administered. During the CPAP trials, electrical activity of the diaphragm (EA.sub.di), transdiaphragmatic pressure (P.sub.di), and flow were measured. Neuromechanical efficiency (primary outcome parameter) was calculated. Results Thirty-nine patients were included in the study. Neuromechanical efficiency was not different during the CPAP trial after levosimendan administration compared to the CPAP trial before study medication. Tidal volume and minute ventilation were higher after levosimendan administration (11 and 21%, respectively), whereas EA.sub.di and P.sub.di were higher in both groups in the CPAP trial after study medication compared to the CPAP trial before study medication. Conclusions Levosimendan does not improve diaphragm contractile efficiency.

Published
2019
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23. Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE)

Author

Pham, Tài, Heunks, Leo, Bellani, Giacomo, Madotto, Fabiana, Aragao, Irene, Beduneau, Gaëtan, Goligher, Ewan C, Grasselli, Giacomo, Laake, Jon Henrik, Mancebo, Jordi, Peñuelas, Oscar, Piquilloud, Lise, Pesenti, Antonio, Wunsch, Hannah, van Haren, Frank, Brochard, Laurent, Laffey, John G, Abrough, Fekri, Acharya, Subhash P, Amin, Pravin, Arabi, Yaseen, Bauer, Philippe, Beitler, Jeremy, Berkius, Johan, Bugedo, Guillermo, Camporota, Luigi, Cerny, Vladimir, Cho, Young-Jae, Clarkson, Kevin, Estenssoro, Elisa, Goligher, Ewan, Gritsan, Alexey, Hashemian, Seyed Mohammadreza, Hermans, Greet, Heunks, Leo M, Jovanovic, Bojan, Kurahashi, Kiyoyasu, Matamis, Dimitrios, Moerer, Onnen, Molnar, Zsolt, Ozyilmaz, Ezgi, Panka, Bernardo, Papali, Alfred, Peñuelas, Óscar, Perbet, Sébastien, Qiu, Haibo, Razek, Assem Abdel, Rittayamai, Nuttapol, Roldan, Rollin, Serpa Neto, Ary, Szuldrzynski, Konstanty, Talmor, Daniel, Tomescu, Dana, Van Haren, Frank, Villagomez, Asisclo, Zeggwagh, Amine Ali, Abe, Toshikazu, Aboshady, Abdelrhman, Acampo-de Jong, Melanie, Acharya, Subhash, Adderley, Jane, Adiguzel, Nalan, Agrawal, Vijay Kumar, Aguilar, Gerardo, Aguirre, Gaston, Aguirre-Bermeo, Hernan, Ahlström, Björn, Akbas, Türkay, Akker, Mustafa, Al Sadeh, Ghamdan, Alamri, Sultan, Algaba, Angela, Ali, Muneeb, Aliberti, Anna, Allegue, Jose Manuel, Alvarez, Diana, Amador, Joaquin, Andersen, Finn H, Ansari, Sharique, Apichatbutr, Yutthana, Apostolopoulou, Olympia, Arellano, Daniel, Arica, Mestanza, Arikan, Huseyin, Arinaga, Koichi, Arnal, Jean-Michel, Asano, Kengo, Asín-Corrochano, Marta, Avalos Cabrera, Jesus Milagrito, Avila Fuentes, Silvia, Aydemir, Semih, Aygencel, Gulbin, Azevedo, Luciano, Bacakoglu, Feza, Badie, Julio, Baedorf Kassis, Elias, Bai, Gabriela, Balaraj, Govindan, Ballico, Bruno, Banner-Goodspeed, Valerie, Banwarie, Preveen, Barbieri, Rosella, Baronia, Arvind, Barrett, Jonathan, Barrot, Loïc, Barrueco-Francioni, Jesus Emilio, Barry, Jeffrey, Bawangade, Harshal, Beavis, Sarah, Beck, Eduardo, Beehre, Nina, Belenguer Muncharaz, Alberto, Belliato, Mirko, Bellissima, Agrippino, Beltramelli, Rodrigo, Ben Souissi, Asma, Benitez-Cano, Adela, Benlamin, Mohamed, Benslama, Abdellatif, Bento, Luis, Benvenuti, Daniela, Bernabe, Laura, Bersten, Andrew, Berta, Giacomo, Bertini, Pietro, Bertram-Ralph, Elliot, Besbes, Mohamed, Bettini, Lisandro Roberto, Beuret, Pascal, Bewley, Jeremy, Bezzi, Marco, Bhakhtiani, Lakshay, Bhandary, Rakesh, Bhowmick, Kaushik, Bihari, Shailesh, Bissett, Bernie, Blythe, David, Bocher, Simon, Boedjawan, Narain, Bojanowski, Christine M, Boni, Elisa, Boraso, Sabrina, Borelli, Massimo, Borello, Silvina, Borislavova, Margarita, Bosma, Karen J, Bottiroli, Maurizio, Boyd, Owen, Bozbay, Suha, Briva, Arturo, Bruel, Cédric, Bruni, Andrea, Buehner, Ulrike, Bulpa, Pierre, Burt, Karen, Buscot, Mathieu, Buttera, Stefania, Cabrera, Jorge, Caccese, Roberta, Caironi, Pietro, Canchos Gutierrez, Ivan, Canedo, Nancy, Cani, Alma, Cappellini, Iacopo, Carazo, Jesus, Cardonnet, Luis Pablo, Carpio, David, Carriedo, Demetrio, Carrillo, Ramón, Carvalho, João, Caser, Eliana, Castelli, Antonio, Castillo Quintero, Manuel, Castro, Heloisa, Catorze, Nuno, Cengiz, Melike, Cereijo, Enrique, Ceunen, Helga, Chaintoutis, Christos, Chang, Youjin, Chaparro, Gustavogcha, Chapman, Carmel, Chau, Simon, Chavez, Cecilia Eugenia, Chelazzi, Cosimo, Chelly, Jonathan, Chemouni, Frank, Chen, Kai, Chena, Ariel, Chiarandini, Paolo, Chilton, Phil, Chiumello, Davide, Chou-Lie, Yvette, Chudeau, Nicolas, Cinel, Ismail, Cinnella, Gilda, Clark, Michele, Clark, Thomas, Clementi, Stefano, Coaguila, Luis, Codecido, Alexis Jaspe, Collins, Amy, Colombo, Riccardo, Conde, Juan, Consales, Guglielmo, Cook, Tim, Coppadoro, Andrea, Cornejo, Rodrigo, Cortegiani, Andrea, Coxo, Cristina, Cracchiolo, Andrea Neville, Crespo Ramirez, Mónica, Crova, Philippe, Cruz, José, Cubattoli, Lucia, Çukurova, Zafer, Curto, Francesco, Czempik, Piotr, D'Andrea, Rocco, da Silva Ramos, Fernando, Dangers, Laurence, Danguy des Déserts, Marc, Danin, Pierre-Eric, Dantas, Fabianne, Daubin, Cédric, Dawei, Wu, de Haro, Candelaria, de Jesus Montelongo, Felipe, De Mendoza, Diego, de Pablo, Raúl, De Pascale, Gennaro, De Rosa, Silvia, Decavèle, Maxens, Declercq, Pierre-Louis, Deicas, Alberto, del Carmen Campos Moreno, María, Dellamonica, Jean, Delmas, Benjamin, Demirkiran, Oktay, Demirkiran, Hilmi, Dendane, Tarek, di Mussi, Rossella, Diakaki, Chrysi, Diaz, Anatilde, Diaz, Willy, Dikmen, Yalim, Dimoula, Aikaterini, Doble, Patricia, Doha, Nagwa, Domingos, Guilherme, Dres, Martin, Dries, David, Duggal, Abhijit, Duke, Graeme, Dunts, Pavel, Dybwik, Knut, Dykyy, Maksym, Eckert, Philippe, Efe, Serdar, Elatrous, Souheil, Elay, Gülseren, Elmaryul, Abubaker S, Elsaadany, Mohamed, Elsayed, Hany, Elsayed, Samar, Emery, Malo, Ena, Sébastien, Eng, Kevin, Englert, Joshua A, Erdogan, Elif, Ergin Ozcan, Perihan, Eroglu, Ege, Escobar, Miguel, Esen, Figen, Esen Tekeli, Arzu, Esquivel, Alejandro, Esquivel Gallegos, Helbert, Ezzouine, Hanane, Facchini, Alberto, Faheem, Mohammad, Fanelli, Vito, Farina, Maria Fernanda, Fartoukh, Muriel, Fehrle, Lutz, Feng, Feng, Feng, Yufeng, Fernandez, Irene, Fernandez, Borja, Fernandez-Rodriguez, Maria Lorena, Ferrando, Carlos, Ferreira da Silva, Maria João, Ferreruela, Mireia, Ferrier, Janet, Flamm Zamorano, Matias Jesús, Flood, Laura, Floris, Leda, Fluckiger, Martin, Forteza, Catalina, Fortunato, Antonella, Frans, Eric, Frattari, Antonella, Fredes, Sebastian, Frenzel, Tim, Fumagalli, Roberto, Furche, Mariano Andres, Fusari, Maurizio, Fysh, Edward, Galeas-Lopez, Juan Luis, Galerneau, Louis-Marie, Garcia, Analía, Garcia, María Fernanda, Garcia, Elisabet, Garcia Olivares, Pablo, Garlicki, Jaroslaw, Garnero, Aude, Garofalo, Eugenio, Gautam, Prabha, Gazenkampf, Andrey, Gelinotte, Stéphanie, Gelormini, Domenico, Ghrenassia, Etienne, Giacomucci, Angelo, Giannoni, Robert, Gigante, Andrea, Glober, Nancy, Gnesin, Paolo, Gollo, Yari, Gomaa, Dina, Gomero Paredes, Rosita, Gomes, Rui, Gomez, Raúl Alejandro, Gomez, Oscar, Gomez, Aroa, Gondim, Louise, Gonzalez, Manuel, Gonzalez, Isabel, Gonzalez-Castro, Alejandro, Gordillo Romero, Orlando, Gordo, Federico, Gouin, Philippe, Graf Santos, Jerónimo, Grainne, Rooney, Grando, Matilde, Granov Grabovica, Sanja, Grasso, Salvatore, Grasso, Rinaldo, Grimmer, Lisa, Grissom, Colin, Gu, Qing, Guan, Xiang-Dong, Guarracino, Fabio, Guasch, Neus, Guatteri, Luca, Gueret, Renaud, Guérin, Claude, Guerot, Emmanuel, Guitard, Pierre-Gildas, Gül, Fethi, Gumus, Ayca, Gurjar, Mohan, Gutierrez, Patricia, Hachimi, Abdelhamid, Hadzibegovic, Adi, Hagan, Samantha, Hammel, Clare, Han Song, Joo, Hanlon, Gabrielle, Heines, Serge, Henriksson, Johanna, Herbrecht, Jean-Etienne, Heredia Orbegoso, Gabriel Omar, Hermon, Andrew, Hernandez, Rosana, Hernandez, Carmen, Herrera, Luis, Herrera-Gutierrez, Manuel, Hidalgo, Juan, Hill, Dianne, Holmquist, Dagmar, Homez, Marcela, Hongtao, Xia, Hormis, Anil, Horner, Daniel, Hornos, M Carmen, Hou, Meihong, House, Stacy, Housni, Brahim, Hugill, Keith, Humphreys, Sally, Humbert, Louis, Hunter, Stephanie, Hwa Young, Lee, Iezzi, Nicolas, Ilutovich, Santiago, Inal, Volkan, Innes, Richard, Ioannides, Panagiotis, Iotti, Giorgio Antonio, Ippolito, Mariachiara, Irie, Hiromasa, Iriyama, Hiroki, Itagaki, Taiga, Izura, Javier, Izza, Santiago, Jabeen, Rakhshanda, Jamaati, Hamidreza, Jamadarkhana, Sunil, Jamoussi, Amira, Jankowski, Milosz, Jaramillo, Luis Alberto, Jeon, Kyeongman, Jeong Lee, Seok, Jeswani, Deepak, Jha, Simant, Jiang, Liangyan, Jing, Chen, Jochmans, Sébastien, Johnstad, Bror Anders, Jongmin, Lee, Joret, Aurélie, Junhasavasdikul, Detajin, Jurado, Maria Teresa, Kam, Elisa, Kamohara, Hidenobu, Kane, Caroline, Kara, Iskender, Karakurt, Sait, Karnjanarachata, Cherdkiat, Kataoka, Jun, Katayama, Shinshu, Kaushik, Shuchi, Kelebek Girgin, Nermin, Kerr, Kathryn, Kerslake, Ian, Khairnar, Prakash, Khalid, Abidi, Khan, Akram, Khanna, Ashish K, Khorasanee, Reza, Kienhorst, Dieneke, Kirakli, Cenk, Knafelj, Rihard, Kol, Mark Kol, Kongpolprom, Napplika, Kopitko, Csaba, Korkmaz Ekren, Pervin, Kubisz-Pudelko, Agnieszka, Kulcsar, Zoltan, Kumasawa, Junji, Kuriyama, Akira, Kutchak, Fernanda, Labarca, Eduardo, Labat, Françoise, Laborda, César, Laca Barrera, Manuel Alberto, Lagache, Laurie, Landaverde Lopez, Antonio, Lanspa, Michael, Lascari, Valeria, Le Meur, Matthieu, Lee, Su Hwan, Lee, Young Ju, Lee, Jinwoo, Lee, Won-Yeon, Lee, Jarone, Legernaes, Terje, Leiner, Tamaas, Lemiale, Virginie, Leonor, Tiago, Lepper, Philipp M, Li, Dahuan, Li, Hongbin, Li, Oleg, Lima, Ana Raquel, Lind, Dan, Litton, Edward, Liu, Ning, Liu, Ling, Liu, Jialin, Llitjos, Jean-François, Llorente, Beatriz, Lopez, Rodolfo, Lopez, Claudia Elizabeth, Lopez Nava, Claudia, Lovazzano, Pablo, Lu, Min, Lucchese, Francesca, Lugano, Manuela, Lugo Goytia, Gustavo, Luo, Hua, Lynch, Ceri, Macheda, Sebastiano, Madrigal Robles, Victor Hugo, Maggiore, Salvatore Maurizio, Magret Iglesias, Mònica, Malaga, Peter, Mallapura Maheswarappa, Harish, Malpartida, Guillermo, Malyarchikov, Andrey, Mansson, Helena, Manzano, Anaid, Marey, Ismael, Marin, Nathalie, Marin, Maria del Carmen, Markman, Eliana, Martin, Felix, Martin, Alex, Martin Dal Gesso, Cristina, Martinez, Felipe, Martínez-Fidalgo, Conchita, Martin-Loeches, Ignacio, Mas, Arantxa, Masaaki, Sakuraya, Maseda, Emilio, Massa, Eleni, Mattsson, Anna, Maugeri, Jessica, McCredie, Victoria, McCullough, James, McGuinness, Shay, McKown, Andrew, Medve, László, Mei, Chengqing, Mellado Artigas, Ricard, Mendes, Vitor, Mervat, Mohamed Khalaf Ebraheim, Michaux, Isabelle, Mikhaeil, Michael, Milagros, Olga, Milet, Igor, Millan, Maria Teresa, Minwei, Zhang, Mirabella, Lucia, Mishra, Sanghamitra, Mistraletti, Giovanni, Mochizuki, Katsunori, Moghal, Arif, Mojoli, Francesco, Molin, Alexandre, Montiel, Raquel, Montini, Luca, Monza, Gianmario, Mora Aznar, Maria, Morakul, Sunthiti, Morales, Maria, Moreno Torres, Daniel, Morocho Tutillo, Diego Rolando, Motherway, Catherine, Mouhssine, Doumiri, Mouloudi, Eleni, Muñoz, Tapia, Munoz de Cabo, Carlos, Mustafa, Mohamed, Muthuchellappan, Radhakrishnan, Muthukrishnan, Muraleekrishnan, Muttini, Stefano, Nagata, Isao, Nahar, Dick, Nakanishi, Misuzu, Nakayama, Izumi, Namendys-Silva, Silvio Antonio, Nanchal, Rahul, Nandakumar, Sivakumar, Nasi, Alessandra, Nasir, Kamal, Navalesi, Paolo, Naz Aslam, Tayyba, Nga Phan, Thuy, Nichol, Alistair, Niiyama, Shuhei, Nikolakopoulou, Sofia, Nikolic, Elena, Nitta, Kenichi, Noc, Marko, Nonas, Stephanie, Nseir, Saad, Nur Soyturk, Ayse, Obata, Yukako, Oeckler, Richard, Oguchi, Moe, Ohshimo, Shinichiro, Oikonomou, Marina, Ojados, Agueda, Oliveira, Maria Teresa, Oliveira Filho, Wilson, Oliveri, Carlo, Olmos, Aitor, Omura, Kazuya, Orlandi, Maria Cristina, Orsenigo, Francesca, Ortiz-Ruiz De Gordoa, Laura, Ota, Kei, Ovalle Olmos, Rainier, Öveges, Nándo, Oziemski, Peter, Ozkan Kuscu, Ozlem, Özyilmaz, Ezgi, Pachas Alvarado, Fernando, Pagella, Gonzalo, Palaniswamy, Vijayanand, Palazon Sanchez, Eugenio Luis, Palmese, Salvatore, Pan, Guojun, Pan, Wensen, Papanikolaou, Metaxia, Papavasilopoulou, Theonymfi, Parekh, Ameet, Parke, Rachael, Parrilla, Francisco J, Parrilla, Dácil, Pasha, Taha, Pasin, Laura, Patão, Luis, Patel, Mayur, Patel, Grisma, Pati, Basanta Kumar, Patil, Jayaprakash, Pattnaik, Saroj, Paul, Daniel, Pavesi, Maurizio, Pavlotsky, Vanesa Alejandra, Paz, Graciela, Paz, Enrique, Pecci, Elisabetta, Pellegrini, Carlos, Peña Padilla, Andrea Gabriela, Perchiazzi, Gaetano, Pereira, Tiago, Pereira, Vera, Perez, Manuel, Perez Calvo, Cesar, Perez Cheng, Meisy, Perez Maita, Ronald, Pérez-Araos, Rodrigo, Perez-Teran, Purificación, Perez-Torres, David, Perkins, Gavin, Persona, Paolo, Petnak, Tananchai, Petrova, Marina, Pham, Tai, Philippart, François, Picetti, Edoardo, Pierucci, Elisabetta, Piervincenzi, Edoardo, Pinciroli, Riccardo, Pintado, Maria-Consuelo, Piraino, Thomas, Piras, Stephanie, Piras, Claudio, Pirompanich, Pattarin, Pisani, Luigi, Platas, Enrique, Plotnikow, Gustavo, Porras, Willy, Porta, Virginia, Portilla, Mariana, Portugal, José, Povoa, Pedro, Prat, Gwenael, Pratto, Romina, Preda, Gabriel, Prieto, Isidro, Prol-Silva, Estefania, Pugh, Richard, Qi, Yupeng, Qian, Chuanyun, Qin, Tiehe, Qu, Hongping, Quintana, Teobaldo, Quispe Sierra, Rosari, Quispe Soto, Rocio, Rabbani, Raihan, Rabee, Mohamed, Rabie, Ahmed, Rahe Pereira, Maria Augusta, Rai, Ashish, Raj Ashok, Sundar, Rajab, Mostafa, Ramdhani, Navin, Ramey, Elizabeth, Ranieri, Marco, Rathod, Darshana, Ray, Banambar, Redwanul Huq, Shihan Mahmud, Regli, Adrian, Reina, Rosa, Resano Sarmiento, Natalia, Reynaud, Faustine, Rialp, Gemma, Ricart, Pilar, Rice, Todd, Richardson, Angus, Rieder, Marcelo, Rinket, Martin, Rios, Fernando, Risso Vazquez, Alejandro, Riva, Ivano, Rivette, Monaly, Roca, Oriol, Roche-Campo, Ferran, Rodriguez, Covadonga, Rodriguez, Gabriel, Rodriguez Gonzalez, Daniel, Rodriguez Tucto, Xandra Yanina, Rogers, Angela, Romano, María Elena, Rørtveit, Linda, Rose, Alastair, Roux, Damien, Rouze, Anahita, Rubatto Birri, Paolo Nahuel, Ruilan, Wang, Ruiz Robledo, Aldana, Ruiz-Aguilar, Antonio Luis, Sadahiro, Tomohito, Saez, Ignacio, Sagardia, Judith, Saha, Rajnish, Saha, Rohit, Saiphoklang, Narongkorn, Saito, Shigeki, Salem, Maie, Sales, Gabriele, Salgado, Patricia, Samavedam, Srinivas, Sami Mebazaa, Mhamed, Samuelsson, Line, San Juan Roman, Nandyelly, Sanchez, Patricia, Sanchez-Ballesteros, Jesus, Sandoval, Yazcitk, Sani, Emanuele, Santos, Martin, Santos, Carla, Sanui, Masamitsu, Saravanabavan, Lakshmikanthcharan, Sari, Sema, Sarkany, Agnes, Sauneuf, Bertrand, Savioli, Monica, Sazak, Hilal, Scano, Riccardo, Schneider, Francis, Schortgen, Frédérique, Schultz, Marcus J, Schwarz, Gabriele Leonie, Seçkin Yücesoy, Faruk, Seely, Andrew, Seiler, Frederik, Seker Tekdos, Yasemin, Seok Chan, Kim, Serano, Luca, Serednicki, Wojciech, Setten, Mariano, Shah, Asim, Shah, Bhagyesh, Shang, You, Shanmugasundaram, Pradeep, Shapovalov, Konstantin, Shebl, Eman, Shiga, Takuya, Shime, Nobuaki, Shin, 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Short, Jack, Shuhua, Chen, Siddiqui, Sughrat, Silesky Jimenez, Juan Ignacio, Silva, Daniel, Silva Sales, Betania, Simons, Koen, Sjøbø, Brit Ågot, Slessor, David, Smiechowicz, Jakub, Smischney, Nathan, Smith, Paul, Smith, Tim, Smith, Mark, Snape, Sarah, Snyman, Lindi, Soetens, Filiep, Sook Hong, Kyung, Sosa Medellin, Miguel Ángel, Soto, Giovanna, Souloy, Xavier, Sousa, Elsa, Sovatzis, Stefania, Sozutek, Didem, Spadaro, Savino, Spagnoli, Marco, Spångfors, Martin, Spittle, Nick, Spivey, Mike, Stapleton, Andrew, Stefanovic, Branislava, Stephenson, Lorraine, Stevenson, Elizabeth, Strand, Kristian, Strano, Maria Teresa, Straus, Slavenka, Sun, Chenliang, Sun, Rongqing, Sundaram, Venkat, SunPark, Tai, Surlemont, Elisabeth, Sutherasan, Yuda, Szabo, Zsuzsanna, Tainter, Christopher, Takaba, Akihiro, Tallott, Mandy, Tamasato, Tamasato, Tang, Zhanhong, Tangsujaritvijit, Viratch, Taniguchi, Leandro, Taniguchi, Daisuke, Tarantino, Fabio, Teerapuncharoen, Krittika, Temprano, Susana, Terragni, Pierpaolo, Terzi, Nicola, Thakur, Anand, Theerawit, Pongdhep, Thille, Arnaud W, Thomas, Matt, Thungtitigul, Poungrat, Thyrault, Martial, Tilouch, Nejla, Timenetsky, Karina, Tirapu, Juna, Todeschini, Manuel, Tomas, Roser, Tomaszewski, Christian, Tonetti, Tommaso, Tonnelier, Alexandre, Trinder, John, Trongtrakul, Konlawij, Truwit, Jonathon, Tsuei, Betty, Tulaimat, Aiman, Turan, Sema, Turkoglu, Melda, Tyagi, Sanjeev, Ubeda, Alejandro, Vagginelli, Federica, Valenti, María Florencia, Vallverdu, Imma, Van Axel, Alisha, van den Hul, Ingrid, van der Hoeven, Han, Van Der Meer, Nardo, Vanhoof, Marc, Vargas-Ordoñez, Mónica, Vaschetto, Rosanna, Vascotto, Ettore, Vatsik, Maria, Vaz, Ana, Vazquez-Sanchez, Antonia, Ventura, Sara, Vermeijden, Jan Wytze, Vidal, Anxela, Vieira, Jocyelle, Vilela Costa Pinto, Bruno, Villagra, Ana, Villegas Succar, Cristina, Vinorum, Ole Georg, Vitale, Giovanni, Vj, Ramesh, Vochin, Ana, Voiriot, Guillaume, Volta, Carlo Alberto, von Seth, Magnu, Wajdi, Maazouzi, Walsh, Don, Wang, Shouhong, Wardi, Gabriel, Ween-Velken, Nils Christian, Wei, Bi-Lin, Weller, Dolf, Welsh, Deborah, Welters, Ingeborg, Wert, Michael, Whiteley, Simon, Wilby, Elizabeth, Williams, Erin, Williams, Karen, Wilson, Antoinette, Wojtas, Jadwiga, Won Huh, Jin, Wrathall, David, Wright, Christopher, Wu, Jian-Feng, Xi, Guo, Xing, Zheng-Jiang, Xu, Hongyang, Yamamoto, Kotaro, Yan, Jie, Yáñez, Julio, Yang, Xiaobo, Yates, Elliot, Yazicioglu Mocin, Ozlem, Ye, Zhenglong, Yildirim, Fatma, Yoshida, Norifumi, Yoshido, Hector Higo Leon, Young Lee, Bo, Yu, Rongguo, Yu, Gong, Yu, Tao, Yuan, Boyun, Yuangtrakul, Nadwipa, Yumoto, Tetsuya, Yun, Xie, Zakalik, Graciela, Zaki, Ahmad, Zalba-Etayo, Begoña, Zambon, Massimo, Zang, Bin, Zani, Gianluca, Zarka, Jonathan, Zerbi, Simone Maria, Zerman, Avsar, Zetterquist, Harald, Zhang, Jiuzhi, Zhang, Hongwen, Zhang, Wei, Zhang, Guoxiu, Zhang, Weixin, Zhao, Hongsheng, Zheng, Jia, Zhu, Bin, Zumaran, Ronald, Pham T., Heunks L., Bellani G., Madotto F., Aragao I., Beduneau G., Goligher E. C., Grasselli G., Laake J. H., Mancebo J., et al., Intensive Care Medicine, ACS - Diabetes & metabolism, ACS - Microcirculation, ACS - Pulmonary hypertension & thrombosis, AII - Inflammatory diseases, Intensive Care, Econometrics, Neurosurgery, Cardiothoracic Surgery, and Internal Medicine

Subjects
Pulmonary and Respiratory Medicine, Internal Medicine Sciences, Klinik Tıp, RESPIRATORY SYSTEM, Dahili Tıp Bilimleri, Göğüs Hastalıkları ve Allerji, CLINICAL MEDICINE, Sağlık Bilimleri, Clinical Medicine (MED), Tıp, SOLUNUM SİSTEMİ, Mechanical ventilation, N/A, Health Sciences, Settore MED/41 - ANESTESIOLOGIA, Akciğer ve Solunum Tıbbı, Medicine, Klinik Tıp (MED), Chest Diseases and Allergy
Abstract

Background: Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients requiring at least 2 days of invasive mechanical ventilation. Methods: WEAN SAFE was an international, multicentre, prospective, observational cohort study done in 481 intensive care units in 50 countries. Eligible participants were older than 16 years, admitted to a participating intensive care unit, and receiving mechanical ventilation for 2 calendar days or longer. We defined weaning initiation as the first attempt to separate a patient from the ventilator, successful weaning as no reintubation or death within 7 days of extubation, and weaning eligibility criteria based on positive end-expiratory pressure, fractional concentration of oxygen in inspired air, and vasopressors. The primary outcome was the proportion of patients successfully weaned at 90 days. Key secondary outcomes included weaning duration, timing of weaning events, factors associated with weaning delay and weaning failure, and hospital outcomes. This study is registered with ClinicalTrials.gov, NCT03255109. Findings: Between Oct 4, 2017, and June 25, 2018, 10 232 patients were screened for eligibility, of whom 5869 were enrolled. 4523 (77·1%) patients underwent at least one separation attempt and 3817 (65·0%) patients were successfully weaned from ventilation at day 90. 237 (4·0%) patients were transferred before any separation attempt, 153 (2·6%) were transferred after at least one separation attempt and not successfully weaned, and 1662 (28·3%) died while invasively ventilated. The median time from fulfilling weaning eligibility criteria to first separation attempt was 1 day (IQR 0–4), and 1013 (22·4%) patients had a delay in initiating first separation of 5 or more days. Of the 4523 (77·1%) patients with separation attempts, 2927 (64·7%) had a short wean (≤1 day), 457 (10·1%) had intermediate weaning (2–6 days), 433 (9·6%) required prolonged weaning (≥7 days), and 706 (15·6%) had weaning failure. Higher sedation scores were independently associated with delayed initiation of weaning. Delayed initiation of weaning and higher sedation scores were independently associated with weaning failure. 1742 (31·8%) of 5479 patients died in the intensive care unit and 2095 (38·3%) of 5465 patients died in hospital. Interpretation: In critically ill patients receiving at least 2 days of invasive mechanical ventilation, only 65% were weaned at 90 days. A better understanding of factors that delay the weaning process, such as delays in weaning initiation or excessive sedation levels, might improve weaning success rates. Funding: European Society of Intensive Care Medicine, European Respiratory Society.

Published
2023

24. The Prognostic Value of Troponin-T in OHCA Without ST-Segment Elevation: A COACT Trial’s Secondary Analysis

Author

Spoormans, Eva M., primary, Lemkes, Jorrit S., additional, Janssens, Gladys N., additional, van der Hoeven, Nina W., additional, Jewbali, Lucia S.D., additional, Dubois, Eric A., additional, Meuwissen, Martijn, additional, Rijpstra, Tom A., additional, Bosker, Hans A., additional, Blans, Michiel J., additional, Bleeker, Gabe B., additional, Baak, Remon, additional, Vlachojannis, Georgios J., additional, Eikemans, Bob J.W., additional, van der Harst, Pim, additional, van der Horst, Iwan C.C., additional, Voskuil, Michiel, additional, van der Heijden, Joris J., additional, Beishuizen, Albertus, additional, Stoel, Martin, additional, Camaro, Cyril, additional, van der Hoeven, Hans, additional, Henriques, José P., additional, Vlaar, Alexander P.J., additional, Vink, Maarten A., additional, van den Bogaard, Bas, additional, Heestermans, Ton A.C.M., additional, de Ruijter, Wouter, additional, Delnoij, Thijs S.R., additional, Crijns, Harry J.G.M., additional, Oemrawsingh, Pranobe V., additional, Gosselink, Marcel T.M., additional, Plomp, Koos, additional, Magro, Michael, additional, Elbers, Paul W.G., additional, van der Pas, Stéphanie, additional, and van Royen, Niels, additional

Published
2023
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28. Family participation in essential care activities: Needs, perceptions, preferences, and capacities of intensive care unit patients, relatives, and healthcare providers—An integrative review

Author

General Practice & Nursing Science, Verplegingswetenschap, Cancer, JC onderzoeksprogramma Methodology, Dijkstra, Boukje M., Felten-Barentsz, Karin M., van der Valk, Margriet J.M., Pelgrim, Thomas, van der Hoeven, Hans G., Schoonhoven, Lisette, Ebben, Remco H.A., Vloet, Lilian C.M., General Practice & Nursing Science, Verplegingswetenschap, Cancer, JC onderzoeksprogramma Methodology, Dijkstra, Boukje M., Felten-Barentsz, Karin M., van der Valk, Margriet J.M., Pelgrim, Thomas, van der Hoeven, Hans G., Schoonhoven, Lisette, Ebben, Remco H.A., and Vloet, Lilian C.M.

Published
2023

31. Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients

Author

Timmermans, Kim, Kox, Matthijs, Vaneker, Michiel, van den Berg, Maarten, John, Aaron, van Laarhoven, Arjan, and van der Hoeven, Hans

Subjects
Research, Risk factors, Health aspects, Cytokines -- Research -- Health aspects, Emergency medical services -- Research -- Health aspects, Disease susceptibility -- Research -- Risk factors, Medical research -- Health aspects, Infection -- Risk factors -- Research, Heat shock proteins -- Health aspects -- Research, EDTA -- Research, Gene expression -- Research -- Health aspects, HLA antigens -- Research -- Health aspects, Mitochondrial DNA -- Research -- Health aspects, Medicine, Experimental -- Health aspects, HLA histocompatibility antigens -- Research -- Health aspects, Ethylenediaminetetraacetic acid -- Research, Histocompatibility antigens -- Research -- Health aspects
Abstract

Author(s): Kim Timmermans [sup.1] [sup.2], Matthijs Kox [sup.1] [sup.2], Michiel Vaneker [sup.2] [sup.3], Maarten van den Berg [sup.1], Aaron John [sup.1] [sup.2], Arjan van Laarhoven [sup.4], Hans van der Hoeven [...], Purpose Danger-associated molecular patterns (DAMPs) released of trauma could contribute to an immune suppressed state that renders patients vulnerable towards nosocomial infections. We investigated DAMP release in trauma patients, starting in the prehospital phase, and assessed its relationship with immune suppression and nosocomial infections. Methods Blood was obtained from 166 adult trauma patients at the trauma scene, emergency room (ER), and serially afterwards. Circulating levels of DAMPs and cytokines were determined. Immune suppression was investigated by determination of HLA-DRA gene expression and ex vivo lipopolysaccharide-stimulated cytokine production. Results Compared with healthy controls, plasma levels of nuclear DNA (nDNA) and heat shock protein-70 (HSP70) but not mitochondrial DNA were profoundly increased immediately following trauma and remained elevated for 10 days. Plasma cytokines were increased at the ER, and levels of anti-inflammatory IL-10 but not of pro-inflammatory cytokines peaked at this early time-point. HLA-DRA expression was attenuated directly after trauma and did not recover during the follow-up period. Plasma nDNA (r = -0.24, p = 0.006) and HSP70 (r = -0.38, p < 0.0001) levels correlated negatively with HLA-DRA expression. Ex vivo cytokine production revealed an anti-inflammatory phenotype already at the trauma scene which persisted in the following days, characterized by attenuated TNF-[alpha] and IL-6, and increased IL-10 production. Finally, higher concentrations of nDNA and a further decrease of HLA-DRA expression were associated with infections. Conclusions Plasma levels of DAMPs are associated with immune suppression, which is apparent within minutes/hours following trauma. Furthermore, aggravated immune suppression during the initial phase following trauma is associated with increased susceptibility towards infections.

Published
2016
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34. Ischaemic electrocardiogram patterns and its association with survival in out-of-hospital cardiac arrest patients without ST-segment elevation myocardial infarction: a COACT trials’ post-hoc subgroup analysis

Author

Spoormans, Eva M, primary, Lemkes, Jorrit S, additional, Janssens, Gladys N, additional, Soultana, Ouissal, additional, van der Hoeven, Nina W, additional, Jewbali, Lucia S D, additional, Dubois, Eric A, additional, Meuwissen, Martijn, additional, Rijpstra, Tom A, additional, Bosker, Hans A, additional, Blans, Michiel J, additional, Bleeker, Gabe B, additional, Baak, Remon, additional, Vlachojannis, Georgios J, additional, Eikemans, Bob J W, additional, van der Harst, Pim, additional, van der Horst, Iwan C C, additional, Voskuil, Michiel, additional, van der Heijden, Joris J, additional, Beishuizen, Albertus, additional, Stoel, Martin, additional, Camaro, Cyril, additional, van der Hoeven, Hans, additional, Henriques, José P, additional, Vlaar, Alexander P J, additional, Vink, Maarten A, additional, van den Bogaard, Bas, additional, Heestermans, Ton A C M, additional, de Ruijter, Wouter, additional, Delnoij, Thijs S R, additional, Crijns, Harry J G M, additional, Oemrawsingh, Pranobe V, additional, Gosselink, Marcel T M, additional, Plomp, Koos, additional, Magro, Michael, additional, Elbers, Paul W G, additional, van de Ven, Peter M, additional, and van Royen, Niels, additional

Published
2022
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35. Ischaemic electrocardiogram patterns and its association with survival in out-of-hospital cardiac arrest patients without ST-segment elevation myocardial infarction: a COACT trials' post-hoc subgroup analysis

Author

Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, Soultana, Ouissal, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, van de Ven, Peter M, van Royen, Niels, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, Soultana, Ouissal, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, van de Ven, Peter M, and van Royen, Niels

Published
2022

36. Cost Analysis From a Randomized Comparison of Immediate Versus Delayed Angiography After Cardiac Arrest

Author

Team Medisch, Circulatory Health, Medische Staf Intensive Care, Camaro, Cyril, Bonnes, Judith L, Adang, Eddy M, Spoormans, Eva M, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Rémon, Vlachojannis, George J, Eikemans, Bob J, van der Harst, Pim, van der Horst, Iwan C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Bert, Stoel, Martin, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A, de Ruijter, Wouter, Delnoij, Thijs S, Crijns, Harry J, Jessurun, Gillian A, Oemrawsingh, Pranobe V, Gosselink, Marcel T, Plomp, Koos, Magro, Michael, Elbers, Paul W, van de Ven, Peter M, Lemkes, Jorrit S, van Royen, Niels, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Camaro, Cyril, Bonnes, Judith L, Adang, Eddy M, Spoormans, Eva M, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Rémon, Vlachojannis, George J, Eikemans, Bob J, van der Harst, Pim, van der Horst, Iwan C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Bert, Stoel, Martin, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A, de Ruijter, Wouter, Delnoij, Thijs S, Crijns, Harry J, Jessurun, Gillian A, Oemrawsingh, Pranobe V, Gosselink, Marcel T, Plomp, Koos, Magro, Michael, Elbers, Paul W, van de Ven, Peter M, Lemkes, Jorrit S, and van Royen, Niels

Published
2022

37. Targeted Temperature Management in Out-of-Hospital Cardiac Arrest With Shockable Rhythm: A Post Hoc Analysis of the Coronary Angiography After Cardiac Arrest Trial

Author

Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, Girbes, Armand R J, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, van de Ven, Peter M, van Royen, Niels, Elbers, Paul W G, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, Girbes, Armand R J, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, van de Ven, Peter M, van Royen, Niels, and Elbers, Paul W G

Published
2022

40. Cost Analysis From a Randomized Comparison of Immediate Versus Delayed Angiography After Cardiac Arrest

Author

Camaro, Cyril, primary, Bonnes, Judith L., additional, Adang, Eddy M., additional, Spoormans, Eva M., additional, Janssens, Gladys N., additional, van der Hoeven, Nina W., additional, Jewbali, Lucia S., additional, Dubois, Eric A., additional, Meuwissen, Martijn, additional, Rijpstra, Tom A., additional, Bosker, Hans A., additional, Blans, Michiel J., additional, Bleeker, Gabe B., additional, Baak, Rémon, additional, Vlachojannis, George J., additional, Eikemans, Bob J., additional, van der Harst, Pim, additional, van der Horst, Iwan C., additional, Voskuil, Michiel, additional, van der Heijden, Joris J., additional, Beishuizen, Bert, additional, Stoel, Martin, additional, van der Hoeven, Hans, additional, Henriques, José P., additional, Vlaar, Alexander P., additional, Vink, Maarten A., additional, van den Bogaard, Bas, additional, Heestermans, Ton A., additional, de Ruijter, Wouter, additional, Delnoij, Thijs S., additional, Crijns, Harry J., additional, Jessurun, Gillian A., additional, Oemrawsingh, Pranobe V., additional, Gosselink, Marcel T., additional, Plomp, Koos, additional, Magro, Michael, additional, Elbers, Paul W., additional, van de Ven, Peter M., additional, Lemkes, Jorrit S., additional, and van Royen, Niels, additional

Published
2022
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44. Targeted Temperature Management in Out-of-Hospital Cardiac Arrest With Shockable Rhythm: A Post Hoc Analysis of the Coronary Angiography After Cardiac Arrest Trial

Author

Spoormans, Eva M., primary, Lemkes, Jorrit S., additional, Janssens, Gladys N., additional, van der Hoeven, Nina W., additional, Jewbali, Lucia S. D., additional, Dubois, Eric A., additional, Meuwissen, Martijn, additional, Rijpstra, Tom A., additional, Bosker, Hans A., additional, Blans, Michiel J., additional, Bleeker, Gabe B., additional, Baak, Remon, additional, Vlachojannis, Georgios J., additional, Eikemans, Bob J. W., additional, Girbes, Armand R. J., additional, van der Harst, Pim, additional, van der Horst, Iwan C. C., additional, Voskuil, Michiel, additional, van der Heijden, Joris J., additional, Beishuizen, Albertus, additional, Stoel, Martin, additional, Camaro, Cyril, additional, van der Hoeven, Hans, additional, Henriques, José P., additional, Vlaar, Alexander P. J., additional, Vink, Maarten A., additional, van den Bogaard, Bas, additional, Heestermans, Ton A. C. M., additional, de Ruijter, Wouter, additional, Delnoij, Thijs S. R., additional, Crijns, Harry J. G. M., additional, Jessurun, Gillian A. J., additional, Oemrawsingh, Pranobe V., additional, Gosselink, Marcel T. M., additional, Plomp, Koos, additional, Magro, Michael, additional, van de Ven, Peter M., additional, van Royen, Niels, additional, and Elbers, Paul W. G., additional

Published
2021
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45. COVID-19 is associated with distinct myopathic features in the diaphragm of critically ill patients

Author

Shi, Zhonghua, primary, Bogaards, Sylvia J P, additional, Conijn, Stefan, additional, Onderwater, Yeszamin, additional, Espinosa, Pedro, additional, Bink, Diewertje I, additional, van den Berg, Marloes, additional, van de Locht, Martijn, additional, Bugiani, Marianna, additional, van der Hoeven, Hans, additional, Boon, Reinier A, additional, Heunks, Leo, additional, and Ottenheijm, Coen A C, additional

Published
2021
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48. Dysregulated Innate and Adaptive Immune Responses Discriminate Disease Severity in COVID-19

Author

CDL Staf Research, Circulatory Health, CDL Arcadia, Medische Staf Intensive Care, Infection & Immunity, Arts Assistenten Longziekten, Onderzoeksgroep 6, Janssen, Nico A.F., Grondman, Inge, de Nooijer, Aline H., Boahen, Collins K., Koeken, Valerie A.C.M., Matzaraki, Vasiliki, Kumar, Vinod, He, Xuehui, Kox, Matthijs, Koenen, Hans J.P.M., Smeets, Ruben L., Joosten, Irma, Brüggemann, Roger J.M., Kouijzer, Ilse J.E., van der Hoeven, Hans G., Schouten, Jeroen A., Frenzel, Tim, Reijers, Monique H.E., Hoefsloot, Wouter, Dofferhoff, Anton S.M., van Apeldoorn, Marjan J., Blaauw, Marc J.T., Veerman, Karin, Maas, Coen, Schoneveld, Arjan H., Hoefer, Imo E., Derde, Lennie P.G., van Deuren, Marcel, van der Meer, Jos W.M., van Crevel, Reinout, Giamarellos-Bourboulis, Evangelos J., Joosten, Leo A.B., van den Heuvel, Michel M., Hoogerwerf, Jacobien, de Mast, Quirijn, Pickkers, Peter, Netea, Mihai G., van de Veerdonk, Frank L., CDL Staf Research, Circulatory Health, CDL Arcadia, Medische Staf Intensive Care, Infection & Immunity, Arts Assistenten Longziekten, Onderzoeksgroep 6, Janssen, Nico A.F., Grondman, Inge, de Nooijer, Aline H., Boahen, Collins K., Koeken, Valerie A.C.M., Matzaraki, Vasiliki, Kumar, Vinod, He, Xuehui, Kox, Matthijs, Koenen, Hans J.P.M., Smeets, Ruben L., Joosten, Irma, Brüggemann, Roger J.M., Kouijzer, Ilse J.E., van der Hoeven, Hans G., Schouten, Jeroen A., Frenzel, Tim, Reijers, Monique H.E., Hoefsloot, Wouter, Dofferhoff, Anton S.M., van Apeldoorn, Marjan J., Blaauw, Marc J.T., Veerman, Karin, Maas, Coen, Schoneveld, Arjan H., Hoefer, Imo E., Derde, Lennie P.G., van Deuren, Marcel, van der Meer, Jos W.M., van Crevel, Reinout, Giamarellos-Bourboulis, Evangelos J., Joosten, Leo A.B., van den Heuvel, Michel M., Hoogerwerf, Jacobien, de Mast, Quirijn, Pickkers, Peter, Netea, Mihai G., and van de Veerdonk, Frank L.

Published
2021

49. The effect of immediate coronary angiography after cardiac arrest without ST-segment elevation on left ventricular function. A sub-study of the COACT randomised trial

Author

Team Medisch, Circulatory Health, Medische Staf Intensive Care, Lemkes, Jorrit S, Spoormans, Eva M, Demirkiran, Ahmet, Leutscher, Sophie, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Rémon, Vlachojannis, Georgios J, Eikemans, Bob J W, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, van de Ven, Peter M, van Loon, Ramon B, van Royen, Niels, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Lemkes, Jorrit S, Spoormans, Eva M, Demirkiran, Ahmet, Leutscher, Sophie, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Rémon, Vlachojannis, Georgios J, Eikemans, Bob J W, van der Harst, Pim, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, van de Ven, Peter M, van Loon, Ramon B, and van Royen, Niels

Published
2021

50. Sex differences in patients with out-of-hospital cardiac arrest without ST-segment elevation: A COACT trial substudy

Author

Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, van de Ven, Peter M, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, der Harst, Pim van, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, Appelman, Yolande, van Royen, Niels, Team Medisch, Circulatory Health, Medische Staf Intensive Care, Spoormans, Eva M, Lemkes, Jorrit S, Janssens, Gladys N, van der Hoeven, Nina W, Jewbali, Lucia S D, Dubois, Eric A, van de Ven, Peter M, Meuwissen, Martijn, Rijpstra, Tom A, Bosker, Hans A, Blans, Michiel J, Bleeker, Gabe B, Baak, Remon, Vlachojannis, Georgios J, Eikemans, Bob J W, der Harst, Pim van, van der Horst, Iwan C C, Voskuil, Michiel, van der Heijden, Joris J, Beishuizen, Albertus, Stoel, Martin, Camaro, Cyril, van der Hoeven, Hans, Henriques, José P, Vlaar, Alexander P J, Vink, Maarten A, van den Bogaard, Bas, Heestermans, Ton A C M, de Ruijter, Wouter, Delnoij, Thijs S R, Crijns, Harry J G M, Jessurun, Gillian A J, Oemrawsingh, Pranobe V, Gosselink, Marcel T M, Plomp, Koos, Magro, Michael, Elbers, Paul W G, Appelman, Yolande, and van Royen, Niels

Published
2021

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