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5. Frequentie

Author

Bouter, L. M., Zeegers, M. P. A., van Kuijk, S. M. J., Bouter, L.M., Zeegers, M.P.A., and van Kuijk, S.M.J.

Published
2024
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7. Associatie

Author

Bouter, L. M., Zeegers, M. P. A., van Kuijk, S. M. J., Bouter, L.M., Zeegers, M.P.A., and van Kuijk, S.M.J.

Published
2024
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12. Interventie

Author

Bouter, L. M., Zeegers, M. P. A., van Kuijk, S. M. J., Bouter, L.M., Zeegers, M.P.A., and van Kuijk, S.M.J.

Published
2024
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13. Onderzoeksopzet

Author

Bouter, L. M., Zeegers, M. P. A., van Kuijk, S. M. J., Bouter, L.M., Zeegers, M.P.A., and van Kuijk, S.M.J.

Published
2024
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14. Epidemiologie

Author

Bouter, L. M., Zeegers, M. P. A., van Kuijk, S. M. J., Bouter, L.M., Zeegers, M.P.A., and van Kuijk, S.M.J.

Published
2024
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17. Frequentie

Author

Bouter, L. M., primary, Zeegers, M. P. A., additional, and van Kuijk, S. M. J., additional

Published
2023
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21. Value of ultra-high field MRI in patients with suspected focal epilepsy and negative 3 T MRI (EpiUltraStudy): protocol for a prospective, longitudinal therapeutic study

Author

van Lanen, R. H. G. J., Wiggins, C. J., Colon, A. J., Backes, W. H., Jansen, J. F. A., Uher, D., Drenthen, G. S., Roebroeck, A., Ivanov, D., Poser, B. A., Hoeberigs, M. C., van Kuijk, S. M. J., Hoogland, G., Rijkers, K., Wagner, G. L., Beckervordersandforth, J., Delev, D., Clusmann, H., Wolking, S., Klinkenberg, S., Rouhl, R. P. W., Hofman, P. A. M., and Schijns, O. E. M. G.

Published
2022
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25. Monitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort.

Author

Ghossein, M. A., de Kok, J. W. T. M., Eerenberg, F., van Rosmalen, F., Boereboom, R., Duisberg, F., Verharen, K., Sels, J. E. M., Delnoij, T., Geyik, Z., Mingels, A. M. A., Meex, S. J. R., van Kuijk, S. M. J., van Stipdonk, A. M. W., Ghossein, C., Prinzen, F. W., van der Horst, I. C. C., Vernooy, K., van Bussel, B. C. T., and Driessen, R. G. H.

Abstract

Background: Manually derived electrocardiographic (ECG) parameters were not associated with mortality in mechanically ventilated COVID‐19 patients in earlier studies, while increased high‐sensitivity cardiac troponin‐T (hs‐cTnT) and N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP) were. To provide evidence for vectorcardiography (VCG) measures as potential cardiac monitoring tool, we investigated VCG trajectories during critical illness. Methods: All mechanically ventilated COVID‐19 patients were included in the Maastricht Intensive Care Covid Cohort between March 2020 and October 2021. Serum hs‐cTnT and NT‐proBNP concentrations were measured daily. Conversion of daily 12‐lead ECGs to VCGs by a MATLAB‐based script provided QRS area, T area, maximal QRS amplitude, and QRS duration. Linear mixed‐effect models investigated trajectories in serum and VCG markers over time between non‐survivors and survivors, adjusted for confounders. Results: In 322 patients, 5461 hs‐cTnT, 5435 NT‐proBNP concentrations and 3280 ECGs and VCGs were analyzed. Non‐survivors had higher hs‐cTnT concentrations at intubation and both hs‐cTnT and NT‐proBNP significantly increased compared with survivors. In non‐survivors, the following VCG parameters decreased more when compared to survivors: QRS area (−0.27 (95% CI) (−0.37 to −0.16, p <.01) μVs per day), T area (−0.39 (−0.62 to −0.16, p <.01) μVs per day), and maximal QRS amplitude (−0.01 (−0.01 to −0.01, p <.01) mV per day). QRS duration did not differ. Conclusion: VCG‐derived QRS area and T area decreased in non‐survivors compared with survivors, suggesting that an increase in myocardial damage and tissue loss play a role in the course of critical illness and may drive mortality. These VCG markers may be used to monitor critically ill patients. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Hybrid ablation versus repeated catheter ablation in persistent atrial fibrillation: long-term results of the HARTCAP-AF trial

Author

Van Der Heijden, C A J, primary, Vroomen, M, additional, Weberndorfer, C V, additional, Luermans, J G L M, additional, Chaldoupi, S M, additional, Bidar, E, additional, Vernooy, K, additional, Maessen, J G, additional, Van Kuijk, S M J, additional, La Meir, M, additional, Crijns, H J G M, additional, and Maesen, B A E, additional

Published
2024
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28. Identification of Predictors for Progression of Scoliosis in Rett Syndrome

Author

MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Weeda, J. E., van Kuijk, S. M.J., van den Berg, M. P., Bastiaenen, C. H.G., Borst, H. E., van Rhijn, L. W., de Bie, R. A., MS Orthopaedie Algemeen, Regenerative Medicine and Stem Cells, Weeda, J. E., van Kuijk, S. M.J., van den Berg, M. P., Bastiaenen, C. H.G., Borst, H. E., van Rhijn, L. W., and de Bie, R. A.

Published
2024

29. Quality assurance of radiation therapy after breast-conserving surgery among patients in the BOOG 2013-08 trial

Author

Wintraecken, V. M., Boersma, L. J., van Roozendaal, L. M., de Vries, J., van Kuijk, S. M.J., Vane, M. L.G., van Dalen, T., van der Hage, J. A., Strobbe, L. J.A., Linn, S. C., Lobbes, M. B.I., Poortmans, P. M.P., Tjan-Heijnen, V. C.G., van de Vijver, K. K.B.T., Westenberg, A. H., de Wilt, J. H.W., Smidt, M. L., Simons, J. M., Wintraecken, V. M., Boersma, L. J., van Roozendaal, L. M., de Vries, J., van Kuijk, S. M.J., Vane, M. L.G., van Dalen, T., van der Hage, J. A., Strobbe, L. J.A., Linn, S. C., Lobbes, M. B.I., Poortmans, P. M.P., Tjan-Heijnen, V. C.G., van de Vijver, K. K.B.T., Westenberg, A. H., de Wilt, J. H.W., Smidt, M. L., and Simons, J. M.

Abstract

Background and purpose: In the BOOG 2013-08 trial (NCT02271828), cT1-2N0 breast cancer patients were randomized between breast conserving surgery with or without sentinel lymph node biopsy (SLNB) followed by whole breast radiotherapy (WBRT). While awaiting primary endpoint results (axillary recurrence rate), this study aims to perform a quality assurance analysis on protocol adherence and (incidental) axillary radiation therapy (RT) dose. Materials and methods: Patients were enrolled between 2015 and 2022. Data on prescribed RT and (in 25% of included patients) planning target volumes (PTV) parameters were recorded for axillary levels I-IV and compared between treatment arms. Multivariable linear regression analysis was performed to determine prognostic variables for incidental axillary RT dose. Results: 1,439/1,461 included patients (98.5%) were treated according to protocol and 87 patients (5.9%) received regional RT (SLNB 10.9%, no-SLNB 1.5 %). In 326 patients included in the subgroup analysis, the mean incidental PTV dose at axilla level I was 59.5% of the prescribed breast RT dose. In 5 patients (1.5%) the mean PTV dose at level I was ≥95% of the prescribed breast dose. No statistically or clinically significant differences regarding incidental axillary RT dose were found between treatment arms. Tumour bed boost (yes/no) was associated with a higher incidental mean dose in level I (R2 = 0.035, F(6, 263) = 1.532, p 0.168). Conclusion: The results indicate that RT-protocol adherence was high, and that incidental axillary RT dose was low in the BOOG 2013-08 trial. Potential differences between treatmentarms regarding the primary endpoint can thus not be attributed to different axillary radiation doses.

Published
2024

50. Risk factors for total ankle arthroplasty failure

Author

Hermus, J P S, van Kuijk, S M J, Spekenbrink-Spooren, A, Witlox, M A, Poeze, M, van Rhijn, L W, Arts, J J C, Orthopedie, MUMC+: MA Orthopedie (9), RS: CAPHRI - R3 - Functioning, Participating and Rehabilitation, MUMC+: KIO Kemta (9), Epidemiologie, RS: CAPHRI - R2 - Creating Value-Based Health Care, RS: NUTRIM - R3 - Respiratory & Age-related Health, MUMC+: MA Heelkunde (9), MUMC+: TPZ Netwerk Acute Zorg Limburg (9), Surgery, MUMC+: MA Orthopedie (3), and MUMC+: Centrum voor Bewegen (3)

Subjects
Reoperation, Arthroplasty, Replacement, Ankle, Risk Factors, Humans, Orthopedics and Sports Medicine, Ankle, Prosthesis Failure, Retrospective Studies
Abstract

BACKGROUND: Studies concerning total ankle arthroplasty could be influenced by several forms of bias. Independent national arthroplasty registries represent objective data on survival and patient reported outcomes. The aim of this study was to determine survival and identify risk factors for early failure in a nationwide series of total ankle arthroplasties from the Dutch Arthroplasty Register (LROI).PATIENTS AND METHODS: Data of 810 patients, who received 836 total ankle arthroplasties between 2014 and 2020 were obtained from the Dutch Arthroplasty Register (LROI) with a median follow-up of 38 months (range 1-84 months). Survival was expressed in Kaplan-Meier analysis and associated hazard ratios for implant failure were determined. Implant failure was defined as the need for revision surgery for any reason or (pan)arthrodesis.RESULTS: During follow-up, we recorded 39 failures (4.7%) resulting in a implant survival of 95.3% with a median follow-up of 38 months (range 1-84 months). Medial malleolus osteotomy (HR = 2.27), previous surgery (HR = 1.83), previous osteotomy (HR = 2.82) and previous ligament reconstruction (HR = 2.83) all showed potentially clinically meaningful associations with a higher incidence of implant failure, yet only previous OCD treatment (HR = 6.21), BMI (HR = 1.09) and age (HR = 0.71) were statistically significant.INTERPRETATION: Excellent short-term survival (95.3%) with a median follow-up of 38 months was reported for TAA patients from the Dutch Arthroplasty Register. Patients with a lower age, a higher BMI or who had a prior surgical OCD treatment before TAA surgery appear to have a higher risk for revision after short-term clinical follow-up. Thorough patient selection with emphasis on risk factors associated with early implant failure might be essential to improve TAA survivorship.

Published
2022
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