305 results on '"Van Lanen, Steven G."'
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2. Pyridoxal-5′-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis
3. Pyridoxal-5′-phosphate as an oxygenase cofactor : Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase
4. From Cyclohydrolase to Oxidoreductase: Discovery of Nitrile Reductase Activity in a Common Fold
5. Computer-aided drug design of capuramycin analogues as anti-tuberculosis antibiotics by 3D-QSAR and molecular docking
6. A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products
7. Evidence that oxidative dephosphorylation by the nonheme Fe(II), α‐ketoglutarate
8. Introduction to the special issue: “Natural Product Discovery and Development in the Genomic Era: 2019”
9. The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina
10. A Free-Standing Condensation Enzyme Catalyzing Ester Bond Formation in C-1027 Biosynthesis
11. A Phosphopantetheinylating Polyketide Synthase Producing a Linear Polyene to Initiate Enediyne Antitumor Antibiotic Biosynthesis
12. Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 Involves a New Branching Point in Chorismate Metabolism
13. A High-Throughput Screen for Directed Evolution of the Natural Product Sulfotransferase LipB
14. Enzymatic Cβ–H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases
15. Structure and Function of a Dual Reductase–Dehydratase Enzyme System Involved in p-Terphenyl Biosynthesis
16. Structural characterization of DynU16, a START/Bet v1-like protein involved in dynemicin biosynthesis
17. Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
18. Total synthesis of griseusins and elucidation of the griseusin mechanism of action† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02289a
19. Mithramycin 2′-Oximes with Improved Selectivity, Pharmacokinetics, and Ewing Sarcoma Antitumor Efficacy
20. The crystal structure of AbsH3 : A putative flavin adenine dinucleotide‐dependent reductase in the abyssomicin biosynthesis pathway
21. Fe(II)-Dependent, Uridine-5′-Monophosphate α-Ketoglutarate Dioxygenases in the Synthesis of 5′-Modified Nucleosides
22. Progress in combinatorial biosynthesis for drug discovery
23. chapter 5 Iterative Type I Polyketide Synthases for Enediyne Core Biosynthesis
24. Sugar-Pirating as an Enabling Platform for the Synthesis of 4,6-Dideoxyhexoses
25. Three Self‐resistance Modifications Discovered in Nucleoside Antibiotic Muraymycin
26. Structure Determination, Functional Characterization, and Biosynthetic Implications of Nybomycin Metabolites from a Mining Reclamation Site-Associated Streptomyces
27. Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency
28. Enzymatic Cβ–H Functionalization of l-Arg and l-Leu in Nonribosomally Derived Peptidyl Natural Products: A Tale of Two Oxidoreductases.
29. Baraphenazines A–G, Divergent Fused Phenazine-Based Metabolites from a Himalayan Streptomyces
30. Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics
31. Macrolide derivatives reduce proinflammatory macrophage activation and macrophage‐mediated neurotoxicity
32. The crystal structure of AbsH3: A putative flavin adenine dinucleotide-dependent reductase in the abyssomicin biosynthesis pathway.
33. Self-Resistance during Muraymycin Biosynthesis: a Complementary Nucleotidyltransferase and Phosphotransferase with Identical Modification Sites and Distinct Temporal Order
34. Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics
35. Cover Feature: Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics (ChemMedChem 8/2018)
36. Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics
37. Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471
38. SAM cycles up for colibactin
39. Characterization of the two-component, FAD-dependent monooxygenase SgcC that requires carrier protein-tethered substrates for the biosynthesis of the enediyne antitumor antibiotic C-1027
40. The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis
41. Mechanistic studies of Bacillus subtilis QeuF, the nitrile oxidoreductase involved in queuosine biosynthesis
42. Characterization of the maduropeptin biosynthetic gene cluster from Actinomadura madurae ATCC 39144 supporting a unifying paradigm for enediyne biosynthesis
43. Regiospecific chlorination of (S)-[beta]-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027
44. Characterization of NcsB2 as a promiscuous napthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin
45. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway
46. Antitumor antibiotics: Bleomycin, enediynes, and mitomycin
47. Bi- and Tetracyclic Spirotetronates from the Coal Mine Fire Isolate Streptomyces sp. LC-6-2
48. Antibacterial and Cytotoxic Actinomycins Y6–Y9 and Zp from Streptomyces sp. Strain Gö-GS12
49. Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA)
50. Structure-Based Gene Targeting Discovery of a Novel Bacterial Translocase I Inhibitor, Sphaerimicin**
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