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2,209 results on '"Van den Bergh P"'

1. Disorder of Attention, Motor Control and Perception in Grade 1 Boys and Girls

Author

Monique de Milander, Robert Schall, Mareli Willemse, Jason-Paul Buchholz, Stacey-Lauren Fredericks, Hebeth R. Jonck, and Leandrei van den Bergh

Abstract

Background: Researchers continue to investigate the predictive validity of motor assessment in learners with disorder of attention, motor control and perception (DAMP). Aim: Determine the prevalence of attention-deficit hyperactive disorder (ADHD) and developmental coordination disorder (DCD); assess their association in Grade 1 children. Setting: Two primary schools located within 30 km of the University of the Free State, Bloemfontein. Methods: Attention deficit disorder or attention deficit hyperactive disorder (ADD/ ADHD) was assessed using the strength and weaknesses of ADD/ADHD symptoms normal behaviour rating scale (SWAN) and DCD using the Movement Assessment Battery for Children -- 2 (MABC-2). Results: One-hundred-and-ninety-five children (97 girls; 98 boys) aged 6 years to 8 years participated. MABC-2 and SWAN data were available for 195 and 182 children, respectively. Across both genders, 180 participants (92.3%) had no, 10 (5.1%) had moderate and 5 (2.6%) had severe motor difficulties. No statistically significant association (p = 0.1537) between gender and DCD was found. Similarly, 31 (17.0%) participants had ADHD subtype ADHD-I, 21 (11.5%) ADHD-H and 11 (6.0%) ADHD-C; no significant associations between gender and ADHD-I (p = 0.5579), ADHD-H (p = 0.4938) or ADHD-C (p = 0.7654) were found. There were no significant associations between DCD and the ADHD subtypes ADHD-I (p = 0.2956), ADHD-H (p = 0.7570) and ADHD-C (p = 1.000). Conclusion: Prevalence of DCD in the current study is higher than elsewhere in the world. No significant association between DCD and ADHD was found. Contribution: The relatively high prevalence of DCD in this South African population and its significance in the motor development of young children.

Published
2024

5. The association of quantitative PSMA PET parameters with pathologic ISUP grade: an international multicenter analysis

Author

Soeterik, Timo F. W., Heetman, Joris G., Hermsen, Rick, Wever, Lieke, Lavalaye, Jules, Vinken, Maarten, Bahler, Clinton D., Yong, Courtney, Tann, Mark, Kesch, Claudia, Seifert, Robert, Telli, Tugce, Chiu, Peter Ka-Fung, Wu, Kwan Kit, Zattoni, Fabio, Evangelista, Laura, Segalla, Emma, Barone, Antonio, Ceci, Francesco, Rajwa, Pawel, Marra, Giancarlo, Mazzone, Elio, Van Basten, Jean-Paul A., Van Melick, Harm H. E., Van den Bergh, Roderick C. N., and Gandaglia, Giorgio

Published
2024
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7. Follow-up on patients with initial negative mpMRI target and systematic biopsy for PI-RADS ≥ 3 lesions – an EAU-YAU study enhancing prostate cancer detection

Author

Zattoni, Fabio, Gandaglia, Giorgio, van den Bergh, Roderick C. N., Marra, Giancarlo, Valerio, Massimo, Martini, Alberto, Olivier, Jonathan, Puche – SanzI, Ignacio, Rajwa, Pawel, Maggi, Martina, Campi, Riccardo, Nicoletti, Rossella, Amparore, Daniele, De Cillis, Sabrina, Zhuang, Junlong, Guo, Hongqian, Fuschi, Andrea, Veccia, Alessandro, Ditonno, Francesco, Paulino Pereira, Leonor J., Marquis, Alessandro, Barletta, Francesco, Leni, Riccardo, Kasivisvanathan, Veeru, Antonelli, Alessandro, Rivas, Juan Gomez, Remmers, Sebastiaan, Roobol, Monique J., Briganti, Alberto, Dal Moro, Fabrizio, and Novara, Giacomo

Published
2024
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9. An updated model for predicting side-specific extraprostatic extension in the era of MRI-targeted biopsy

Author

Martini, Alberto, Wever, Lieke, Soeterik, Timo F. W., Rakauskas, Arnas, Fankhauser, Christian Daniel, Grogg, Josias Bastian, Checcucci, Enrico, Amparore, Daniele, Haiquel, Luciano, Rodriguez-sanchez, Lara, Ploussard, Guillaume, Qiang, Peng, Affentranger, Andres, Marquis, Alessandro, Marra, Giancarlo, Ettala, Otto, Zattoni, Fabio, Falagario, Ugo Giovanni, De Angelis, Mario, Kesch, Claudia, Apfelbeck, Maria, Al-Hammouri, Tarek, Kretschmer, Alexander, Kasivisvanathan, Veeru, Preisser, Felix, Lefebvre, Emilie, Olivier, Jonathan, Radtke, Jan Philipp, Carrieri, Giuseppe, Moro, Fabrizio Dal, Boström, Peter, Jambor, Ivan, Gontero, Paolo, Chiu, Peter K., John, Hubert, Macek, Petr, Porpiglia, Francesco, Hermanns, Thomas, van den Bergh, Roderick C. N., van Basten, Jean-Paul A., Gandaglia, Giorgio, and Valerio, Massimo

Published
2024
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13. Development and external evaluation of a self-learning auto-segmentation model for Colorectal Cancer Liver Metastases Assessment (COALA)

Author

Bereska, Jacqueline I., Zeeuw, Michiel, Wagenaar, Luuk, Jenssen, Håvard Bjørke, Wesdorp, Nina J., van der Meulen, Delanie, Bereska, Leonard F., Gavves, Efstratios, Janssen, Boris V., Besselink, Marc G., Marquering, Henk A., van Waesberghe, Jan-Hein T. M., Aghayan, Davit L., Pelanis, Egidijus, van den Bergh, Janneke, Nota, Irene I. M., Moos, Shira, Kemmerich, Gunter, Syversveen, Trygve, Kolrud, Finn Kristian, Huiskens, Joost, Swijnenburg, Rutger-Jan, Punt, Cornelis J. A., Stoker, Jaap, Edwin, Bjørn, Fretland, Åsmund A., Kazemier, Geert, and Verpalen, Inez M.

Published
2024
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22. Cross-border differences in the prevalence and risk factors for carriage of antimicrobial resistance in children attending daycare centers: a point prevalence study in the Netherlands and Belgium

Author

Dequeker, Sara, van Hensbergen, Mitch, den Heijer, Casper D. J., Dhaeze, Wouter, Raven, Stijn F. H., Ewalts-Hakkoer, Helen, Tolsma, Paulien, Willemsen, Ina, van Drunen-Kamp, Karine J., van der Slikke-Verstraten, Krista, Goossens, Herman, Kluytmans-van den Bergh, Marjolein F. Q., and Hoebe, Christian J. P. A.

Published
2024
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31. Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy

Author

Töpf, Ana, Cox, Dan, Zaharieva, Irina T., Di Leo, Valeria, Sarparanta, Jaakko, Jonson, Per Harald, Sealy, Ian M., Smolnikov, Andrei, White, Richard J., Vihola, Anna, Savarese, Marco, Merteroglu, Munise, Wali, Neha, Laricchia, Kristen M., Venturini, Cristina, Vroling, Bas, Stenton, Sarah L., Cummings, Beryl B., Harris, Elizabeth, Marini-Bettolo, Chiara, Diaz-Manera, Jordi, Henderson, Matt, Barresi, Rita, Duff, Jennifer, England, Eleina M., Patrick, Jane, Al-Husayni, Sundos, Biancalana, Valerie, Beggs, Alan H., Bodi, Istvan, Bommireddipalli, Shobhana, Bönnemann, Carsten G., Cairns, Anita, Chiew, Mei-Ting, Claeys, Kristl G., Cooper, Sandra T., Davis, Mark R., Donkervoort, Sandra, Erasmus, Corrie E., Fassad, Mahmoud R., Genetti, Casie A., Grosmann, Carla, Jungbluth, Heinz, Kamsteeg, Erik-Jan, Lornage, Xavière, Löscher, Wolfgang N., Malfatti, Edoardo, Manzur, Adnan, Martí, Pilar, Mongini, Tiziana E., Muelas, Nuria, Nishikawa, Atsuko, O’Donnell-Luria, Anne, Ogonuki, Narumi, O’Grady, Gina L., O’Heir, Emily, Paquay, Stéphanie, Phadke, Rahul, Pletcher, Beth A., Romero, Norma B., Schouten, Meyke, Shah, Snehal, Smuts, Izelle, Sznajer, Yves, Tasca, Giorgio, Taylor, Robert W., Tuite, Allysa, Van den Bergh, Peter, VanNoy, Grace, Voermans, Nicol C., Wanschitz, Julia V., Wraige, Elizabeth, Yoshimura, Kimihiko, Oates, Emily C., Nakagawa, Osamu, Nishino, Ichizo, Laporte, Jocelyn, Vilchez, Juan J., MacArthur, Daniel G., Sarkozy, Anna, Cordell, Heather J., Udd, Bjarne, Busch-Nentwich, Elisabeth M., Muntoni, Francesco, and Straub, Volker

Published
2024
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40. Differential integrated stress response and asparagine production drive symbiosis and therapy resistance of pancreatic adenocarcinoma cells

Author

Halbrook, Christopher J, Thurston, Galloway, Boyer, Seth, Anaraki, Cecily, Jiménez, Jennifer A, McCarthy, Amy, Steele, Nina G, Kerk, Samuel A, Hong, Hanna S, Lin, Lin, Law, Fiona V, Felton, Catherine, Scipioni, Lorenzo, Sajjakulnukit, Peter, Andren, Anthony, Beutel, Alica K, Singh, Rima, Nelson, Barbara S, Van Den Bergh, Fran, Krall, Abigail S, Mullen, Peter J, Zhang, Li, Batra, Sandeep, Morton, Jennifer P, Stanger, Ben Z, Christofk, Heather R, Digman, Michelle A, Beard, Daniel A, Viale, Andrea, Zhang, Ji, Crawford, Howard C, Pasca di Magliano, Marina, Jorgensen, Claus, and Lyssiotis, Costas A

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Rare Diseases, Cancer, Digestive Diseases, Pancreatic Cancer, 2.1 Biological and endogenous factors, Animals, Mice, Humans, Pancreatic Neoplasms, Asparagine, Adenocarcinoma, Symbiosis, Tumor Microenvironment, Immunology, Oncology and carcinogenesis
Abstract

The pancreatic tumor microenvironment drives deregulated nutrient availability. Accordingly, pancreatic cancer cells require metabolic adaptations to survive and proliferate. Pancreatic cancer subtypes have been characterized by transcriptional and functional differences, with subtypes reported to exist within the same tumor. However, it remains unclear if this diversity extends to metabolic programming. Here, using metabolomic profiling and functional interrogation of metabolic dependencies, we identify two distinct metabolic subclasses among neoplastic populations within individual human and mouse tumors. Furthermore, these populations are poised for metabolic cross-talk, and in examining this, we find an unexpected role for asparagine supporting proliferation during limited respiration. Constitutive GCN2 activation permits ATF4 signaling in one subtype, driving excess asparagine production. Asparagine release provides resistance during impaired respiration, enabling symbiosis. Functionally, availability of exogenous asparagine during limited respiration indirectly supports maintenance of aspartate pools, a rate-limiting biosynthetic precursor. Conversely, depletion of extracellular asparagine with PEG-asparaginase sensitizes tumors to mitochondrial targeting with phenformin.

Published
2022

41. Earth stewardship: Shaping a sustainable future through interacting policy and norm shifts

Author

Chapin, F Stuart, Weber, Elke U, Bennett, Elena M, Biggs, Reinette, van den Bergh, Jeroen, Adger, W Neil, Crépin, Anne-Sophie, Polasky, Stephen, Folke, Carl, Scheffer, Marten, Segerson, Kathleen, Anderies, John M, Barrett, Scott, Cardenas, Juan-Camilo, Carpenter, Stephen R, Fischer, Joern, Kautsky, Nils, Levin, Simon A, Shogren, Jason F, Walker, Brian, Wilen, James, and de Zeeuw, Aart

Subjects
Political Science, Human Society, Humans, Policy, Anthropocene, Earth stewardship, Institutions, Market economy, Social norms, Transformation, Ecology
Abstract

Transformation toward a sustainable future requires an earth stewardship approach to shift society from its current goal of increasing material wealth to a vision of sustaining built, natural, human, and social capital-equitably distributed across society, within and among nations. Widespread concern about earth's current trajectory and support for actions that would foster more sustainable pathways suggests potential social tipping points in public demand for an earth stewardship vision. Here, we draw on empirical studies and theory to show that movement toward a stewardship vision can be facilitated by changes in either policy incentives or social norms. Our novel contribution is to point out that both norms and incentives must change and can do so interactively. This can be facilitated through leverage points and complementarities across policy areas, based on values, system design, and agency. Potential catalysts include novel democratic institutions and engagement of non-governmental actors, such as businesses, civic leaders, and social movements as agents for redistribution of power. Because no single intervention will transform the world, a key challenge is to align actions to be synergistic, persistent, and scalable.

Published
2022

42. Benchmark Rating Procedure, Best of Both Worlds? Comparing Procedures to Rate Text Quality in a Reliable and Valid Manner

Author

Bouwer, Renske, Koster, Monica, and van den Bergh, Huub

Abstract

Assessing students' writing performance is essential to adequately monitor and promote individual writing development, but it is also a challenge. The present research investigates a benchmark rating procedure for assessing texts written by upper-elementary students. In two studies we examined whether a benchmark rating procedure (1) leads to reliable and generalisable scores that converge with holistic and analytic ratings, and (2) can be used for rating texts varying in topic and genre. Results support evidence that benchmark ratings are a valid indicator of text quality as they converge with holistic and analytic scores. They are also associated with less rater variance and less task-specific variance, leading to reliable and generalisable ratings. Moreover, a benchmark scale can be used for rating different tasks with the same reliability, at least when texts are written in the same genre. Taken together, a benchmark rating procedure ensures meaningful and useful information on students' writing.

Published
2023
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43. How Teachers Handle Differentiation Dilemmas in the Context of a School's Vision: A Case Study

Author

van Vijfeijken, Marijke, van Schilt-Mol, Tamara, van den Bergh, Linda, Scholte, Ron H. J., and Denessen, Eddie

Abstract

Teachers need to make choices about how they distribute their time and support, and a school's vision may support teachers in making these choices. This study aimed to gain insight into how individual teachers--each with their own beliefs about fair classroom differentiation--handle differentiation dilemmas in the context of their school's vision. A case study was conducted at one primary school with a well-defined vision on classroom differentiation. In this school, quantitative and qualitative data were collected: 25 teachers filled in a questionnaire and four teachers sat for in-depth interviews. Teachers had varying beliefs about differentiation. Some beliefs were in line with the school's vision: these teachers preferred common learning goals and considered it fair to provide extra support to disadvantaged students. However, other teachers preferred individual learning goals and considered it fair to give every student an equal amount of support. Teachers whose vision was similar to that of the school perceived the differentiation dilemmas to be less problematic than teachers whose visions differed from the school's vision. A school vision on fair differentiation may help in making joint agreements, but it does not eliminate differentiation dilemmas. Teachers should discuss the differentiation dilemmas to achieve a shared vision on them.

Published
2023
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44. Effects of Reading Strategy Instruction in English as a Second Language on Students' Academic Reading Comprehension

Author

Yapp, Deborah, de Graaff, Rick, and van den Bergh, Huub

Abstract

The ability to read in a second language (L2) for academic purposes is essential for higher education students. Dutch colleges increasingly use materials in English or teach in English. This can be challenging for L2 readers, especially students entering higher education from vocational studies, who may have less experience with L2 academic reading. Teaching L2 reading programmes containing explicit instruction of reading strategies may benefit higher education students in L2 academic reading, particularly since reading strategies learned in the first language (L1) may not transfer to the L2. In this 7-week L2 reading strategy intervention, 801 first-year polytechnic students learned to use seven reading strategies that were effective according to a meta-analysis of L2 reading strategy studies. Data regarding students reading skills were collected over one academic year, from three treatment waves, using a regression discontinuity design. Three tests of equal difficulty were given to participants. In each wave students completed reading tests several weeks before the intervention, at the beginning and directly after the intervention. Results show that in all three waves the improvement in reading comprehension scores between the second and third measurement (due to the experimental course) significantly exceeded the increase between the first two measurement occasions. Although the intervention was shown to be effective, the effects were to some extent mediated by the previous education level. This study supports the explicit instruction of strategies in L2 reading for students in higher education and welcomes more research into L2 reading strategy interventions for students from vocational backgrounds.

Published
2023
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45. The impact of a second MRI and re-biopsy in patients with initial negative mpMRI-targeted and systematic biopsy for PIRADS ≥ 3 lesions

Author

Zattoni, Fabio, Pereira, Leonor J. Paulino, Marra, Giancarlo, Valerio, Massimo, Olivier, Jonathan, Puche-Sanz, Ignacio, Rajwa, Pawel, Maggi, Martina, Campi, Riccardo, Amparore, Daniele, De Cillis, Sabrina, Junlong, Zhuang, Guo, Hongqian, La Bombarda, Giulia, Fuschi, Andrea, Veccia, Alessandro, Ditonno, Francesco, Marquis, Alessandro, Barletta, Francesco, Leni, Riccardo, Serni, Sergio, Kasivisvanathan, Veeru, Antonelli, Alessandro, Dal Moro, Fabrizio, Rivas, Juan Gomez, van den Bergh, Roderick C. N., Briganti, Alberto, Gandaglia, Giorgio, and Novara, Giacomo

Published
2023
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47. The Added Diagnostic Value of Transcatheter CT Hepatic Arteriography for Intraprocedural Detection of Previously Unknown Colorectal Liver Metastases During Percutaneous Ablation and Impact on the Definitive Treatment Plan

Author

van der Lei, Susan, Opperman, Jip, Dijkstra, Madelon, Kors, Nikita, Boon, Rianne, van den Bemd, Bente A. T., Timmer, Florentine E. F., Nota, Irene M. G. C., van den Bergh, Janneke E., de Vries, Jan J. J., Scheffer, Hester J., Geboers, Bart, Neuss, Timothy, Schouten, Evelien, Lissenberg-Witte, Birgit I., Puijk, Robbert S., and Meijerink, Martijn R.

Published
2023
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48. Governance in the Face of Extreme Events: Lessons from Evolutionary Processes for Structuring Interventions, and the Need to Go Beyond

Author

Levin, Simon A, Anderies, John M, Adger, Neil, Barrett, Scott, Bennett, Elena M, Cardenas, Juan Camilo, Carpenter, Stephen R, Crépin, Anne-Sophie, Ehrlich, Paul, Fischer, Joern, Folke, Carl, Kautsky, Nils, Kling, Catherine, Nyborg, Karine, Polasky, Stephen, Scheffer, Marten, Segerson, Kathleen, Shogren, Jason, van den Bergh, Jeroen, Walker, Brian, Weber, Elke U, and Wilen, James

Subjects
Climate Action, Sustainable Cities and Communities, Resilience, Robustness, Extreme events, Governance, Prevention, Mitigation, Adaptation, Environmental Sciences, Biological Sciences, Ecology
Abstract

The increasing frequency of extreme events, exogenous and endogenous, poses challenges for our societies. The current pandemic is a case in point; but "once-in-a-century" weather events are also becoming more common, leading to erosion, wildfire and even volcanic events that change ecosystems and disturbance regimes, threaten the sustainability of our life-support systems, and challenge the robustness and resilience of societies. Dealing with extremes will require new approaches and large-scale collective action. Preemptive measures can increase general resilience, a first line of protection, while more specific reactive responses are developed. Preemptive measures also can minimize the negative effects of events that cannot be avoided. In this paper, we first explore approaches to prevention, mitigation and adaptation, drawing inspiration from how evolutionary challenges have made biological systems robust and resilient, and from the general theory of complex adaptive systems. We argue further that proactive steps that go beyond will be necessary to reduce unacceptable consequences.

Published
2022

50. How Students Perform Synthesis Tasks: An Empirical Study into Dynamic Process Configurations

Author

Van Steendam, Elke, Vandermeulen, Nina, De Maeyer, Sven, Lesterhuis, Marije, Van den Bergh, Huub, and Rijlaarsdam, Gert

Abstract

In this study we examine process configurations in synthesis tasks. We study whether these configurations are students traits or vary within students per task. In a national survey with a representative sample of 658 Dutch upper-secondary school students, we collected writing tasks, registered students' writing behaviors (via keylogging) and their task perceptions and assessed the quality of their texts. Each participant completed two informative and two argumentative synthesis tasks. Writing process configurations were based on a preselected set of writing behaviors that proved to be related to text quality: time spent on sources and production activities, switching between sources and between sources and text production, and speed of production; with reference to the phase in the process (first, mid, final part). Latent profile analyses distilled four process configurations, some of which were more likely to occur with the informative genre. One process configuration, that is, "Fast text production," was related to qualitatively higher text quality scores than the others. Additionally, at the age of 16-18 a writing process configuration is not a student trait: in most instances, we observed two or more task configurations within students. Writers' task experiences such as topic knowledge and topic interest predicted the occurrence of certain process configurations which could indicate adaptivity. The finding that writing configurations of writers vary even between similar tasks has important implications for the generalizability of (synthesis) writing research on the basis of a single writing task and process per student.

Published
2022
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