75 results on '"Van der Wardt V"'
Search Results
2. Factors associated with return-to-work outcomes in inpatient rehabilitation – a systematic scoping review.
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Föhner, K., Seipp, H., Becker, A., Maulbecker-Armstrong, C., Schneider, A., Seifart, U., and van der Wardt, V.
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MUSCULOSKELETAL system diseases ,PSYCHOLOGY information storage & retrieval systems ,HOSPITAL patients ,MEDICAL information storage & retrieval systems ,SYSTEMATIC reviews ,RESEARCH methodology ,REHABILITATION of people with mental illness ,QUALITY assurance ,DESCRIPTIVE statistics ,RESEARCH funding ,EMPLOYMENT reentry ,REHABILITATION ,LITERATURE reviews ,DATA analysis software ,MEDLINE ,CANCER patient rehabilitation ,AMED (Information retrieval system) - Abstract
Inpatient rehabilitation is common in Germany to improve return-to-work outcomes. The objective of this systematic scoping review was to identify factors associated with return-to-work outcomes in musculoskeletal, psychological and oncological health conditions to improve tailoring of rehabilitation therapies. A search was completed in Embase, Medline, PsycInfo and AMED until May 2023 for articles investigating inpatient rehabilitation including working-age patients with oncological, musculoskeletal, or psychological diseases using a quantitative design and reporting factors associated with return-to-work outcomes. Screening of all titles and abstracts was completed by one reviewer, full texts were read by two reviewers. Quality appraisal and data extraction was completed by two reviewers. Data was analysed using a narrative synthesis. Eighteen studies of moderate quality were included. The review identified a wide range of return-to-work parameters including employment status, work ability, sickness absence, retirement status and duration of employment since rehabilitation. In addition, 48 psychological, health- and work-related factors associated with return-to-work parameters were identified. Only one RCT investigated the relationship between a depression prevention intervention and a return-to-work outcome (work ability), which showed a significant effect. In addition to the depression prevention intervention, only the factor 'health literacy' could be considered modifiable and be addressed as part of an inpatient rehabilitation programme. Furthermore, gradual work reintegration programs and/or workplace interventions in addition to inpatient rehabilitation should be further explored to improve return-to-work outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Strategien zur Bewegungsmotivation bei chronischen muskuloskelettalen Schmerzen: ein systematisches Review
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Heisig, J, Lindner, N, Kornder, N, Reichert, W, Viniol, A, and van der Wardt, V
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Bewegung ist eine wirksame Therapie bei chronischen muskuloskelettalen Schmerzen. Die Herausforderung, Patient:innen mit chronischen Schmerzen längerfristig zu Bewegung zu motivieren, begegnet uns täglich in der Hausarztpraxis. In den letzten 30 Jahren wurden schon zahlreiche [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2022
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4. Sektorübergreifende digitale Fallbesprechung zur Rehabilitation von Menschen mit onkologischen, muskuloskelettalen oder psychischen Erkrankungen: die RehaPro-SERVE-Machbarkeitsstudie
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van der Wardt, V, Seipp, H, Seifart, U, Heitz, A, Rolfs, S, Maulbecker-Armstrong, C, Schneider, A, Kraicker, R, and Becker, A
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Langfristige Arbeitsunfähigkeit und gesundheitliches Erwerbsminderungsrisiko haben sowohl für die Betroffenen als auch gesellschaftlich bedeutende negative Auswirkungen. Wenn die Erwerbsfähigkeit gefährdet ist, können über die gesetzlichen Rentenversicherung [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2022
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5. Offene Bedarfe in der Gesundheitsversorgung von Menschen mit Demenz und deren pflegenden Angehörigen aus der Perspektive der Hausärzte
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Rachor, FLM and van der Wardt, V
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Allein in Deutschland leben gegenwärtig 1,6 Millionen Menschen mit Demenz. Hochrechnungen haben ergeben, dass sich die Prävalenz bis 2050 auf ca. 3 Millionen verdoppeln wird. In der Versorgung von Menschen mit Demenz hat der Hausarzt eine wichtige Funktion. Eine erste [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2021
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6. Strategien zur Bewegungsmotivation bei chronischen Rückenschmerzen: ein systematisches Review
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Heisig, J, Lindner, N, Viniol, A, and van der Wardt, V
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Eine der effektivsten Therapien chronischen Rückenschmerzen zu begegnen ist die regelmäßige Bewegung. Die Hürde zur körperlichen Aktivität ist jedoch besonders hoch, wenn die Schmerzen als sehr intensiv und übermächtig erlebt werden, der Wunsch sich [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2021
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7. Qualitative Interviewstudie über Erwartungen und Wünsche von Patient*innen mit Diabetes mellitus Typ 2 an die hausärztliche Lebensstilberatung zur Bewegungsförderung
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Friedrich, LM and van der Wardt, V
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Ernährung und körperliche Aktivität sind Schlüsselelemente der Prävention sowie der Therapie des Diabetes Mellitus 2 (DM2). Hausarztpraxen, die regelmäßigen und oft engen Kontakt zu den Patient*innen haben, könnten einen Ansatzpunkt darstellen, [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2021
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8. Erfahrungen und Erwartungen von Angehörigen von Patienten mit Migrationshintergrund mit Gedächtnisproblemen oder Demenz in der Hausarztpraxis: eine Interviewstudie
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van der Wardt, V and Shan, CW
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: In Deutschland leben zunehmend Menschen mit Demenz und Migrationshintergrund, die häufig von Angehörigen zuhause gepflegt werden. Die Bedarfe von pflegenden Angehörigen (PA) mit Migrationshintergrund an Hausärzt*innen (HÄ) sind unklar, die Erfahrungen und Erwartungen [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2021
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9. Wie kann eine randomisierte, kontrollierte Studie mit virtuellen Fallbesprechungen im hausärztlichen Setting umgesetzt werden? Machbarkeitsstudie der Studie rehapro-SERVE zur Verringerung von Arbeitsunfähigkeitszeiten von Personen mit gesundheitlichem Erwerbsminderungsrisiko
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Seipp, H, van der Wardt, V, Seifart, U, Heitz, A, Rolfs, S, Maulbecker-Armstrong, C, Schneider, A, Kraicker, R, and Becker, A
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ddc: 610 ,Medicine and health - Abstract
Hintergrund: Arbeitsunfähigkeit aufgrund von gesundheitlicher Beeinträchtigung ist sowohl für die einzelnen Betroffenen als auch gesellschaftlich bedeutsam. Hausärztinnen/Hausärzte nehmen eine zentrale Rolle in der Unterstützung dieser Patienten/Patientinnen ein. [zum vollständigen Text gelangen Sie über die oben angegebene URL]
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- 2021
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10. Tele-rehabilitation for people with dementia in the COVID-19 pandemic: A case-study
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Lorito, C. Di, primary, Duff, C., additional, Rogers, C., additional, Tuxworth, J., additional, Bell, J., additional, Fothergill, R., additional, Wilkinson, L., additional, Bosco, A., additional, Howe, L., additional, O’Brien, R., additional, Godfrey, M., additional, Dunlop, M., additional, Van Der Wardt, V., additional, Booth, V., additional, Logan, P., additional, and Harwood, R., additional
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- 2021
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11. 45A FEASIBILITY STUDY TO ASSESS IF AN INTERVENTION TO IMPROVE OLDER PEOPLE’S REHABILITATIVE EXERCISE ENGAGEMENT (OPREE) CAN BE DELIVERED IN THE NHS
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Anthony, K, primary, van der Wardt, V, additional, Pollock, K, additional, Masud, T, additional, and Logan, P, additional
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- 2018
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12. 34DEVELOPMENT OF THE PROMOTING ACTIVITY, INDEPENDENCE AND STABILITY IN EARLY DEMENTIA AND MILD COGNITIVE IMPAIRMENT (PrAISED) INTERVENTION
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Booth, V, primary, Harwood, R H, additional, Hood-Moore, V, additional, Bramley, T, additional, Hancox, J E, additional, Robertson, K, additional, Hall, J, additional, Van Der Wardt, V, additional, and Logan, P A, additional
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- 2018
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13. Interventions designed to increase older people's exercise engagement: a systematic review
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Anthony, K., primary, Van der Wardt, V., additional, Pollock, K., additional, Robinson, K., additional, Masud, T., additional, and Logan, P., additional
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- 2016
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14. P-272: Falls, gait and dual-tasking in older adults with mild cognitive impairment: A cross-sectional study
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Booth, V., primary, Logan, P., additional, Masud, T., additional, Hood, V., additional, Van Der Wardt, V., additional, Taylor, R., additional, and Harwood, R., additional
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- 2015
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15. P-087: The Balance and the Mind study: baseline data
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van der Wardt, V., primary, Logan, P., additional, Booth, V., additional, Hood, V., additional, Masud, T., additional, and Harwood, R., additional
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- 2015
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16. P-088: Recruitment of people with dementia in primary care –experiences from the HIND study
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van der Wardt, V., primary, Conroy, S., additional, Tomas, W., additional, Logan, P., additional, Harrison, J., additional, Taggar, J., additional, and Gladman, J., additional
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- 2015
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17. P495: The relationship between executive function and falls risk in people with mild cognitive impairment (MCI) and early stage dementia
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Van der Wardt, V., primary, Logan, P., additional, Masud, T., additional, and Harwood, R., additional
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- 2014
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18. P242: Prediction of falls risk with six different biomarkers in mild cognitive impairment using principal component analysis
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de Spiegeleer, A., primary, Masud, T., additional, Greenhaff, P., additional, Van den Noortgate, N., additional, Petrovic, M., additional, Hood, V.L., additional, Gladman, J.R., additional, van der Wardt, V., additional, Harwood, R., additional, and Booth, V., additional
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- 2014
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19. P488: The effects of cognitive and exercise interventions for people with mild cognitive impairment and dementia on carers: a systematic review
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Gondek, D., primary, Patel, D., additional, Pollock, K., additional, das Nair, R., additional, Harwood, R., additional, and van der Wardt, V., additional
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- 2014
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20. P269: A qualitative study into the attitudes of people with mild cognitive impairment and early stages of dementia, and their carers, about falls interventions and risk
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Peach, M., primary, Pollock, K., additional, Harwood, R., additional, van der Wardt, V., additional, and Masud, T., additional
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- 2014
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21. P492: Systematic review into motivational strategies that support adherence to exercise for people with mild cognitive impairment (MCI) or dementia
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Van der Wardt, V., primary, Patel, D., additional, Gondek, D., additional, Pollock, K., additional, Logan, P., additional, Das Nair, R., additional, and Harwood, R., additional
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- 2014
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22. Tele-rehabilitation for people with dementia in the COVID-19 pandemic: A case-study.
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Di Lorito, C., Duff, C., Rogers, C., Tuxworth, J., Bell, J., Fothergill, R., Wilkinson, L., Bosco, A., Howe, L., O'Brien, R., Godfrey, M., Dunlop, M., Van Der Wardt, V., Booth, V., Logan, P., and Harwood, R.
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COVID-19 pandemic ,TELEREHABILITATION ,DEMENTIA ,CAREGIVERS ,THEMATIC analysis - Abstract
Introduction: The Promoting Activity, Independence and Stability in Early Dementia (PrAISED) is delivering an exercise programme for people with dementia. The Lincolnshire partnership NHS foundation Trust successfully delivered PrAISED through a videocalling platform during the COVID-19 pandemic. Objectives: This qualitative case-study identified participants that video delivery worked for, and highlighted its benefits and challenges. Methods: Interviews were conducted with participants with dementia, caregivers and therapists, and analysed through thematic analysis. Results: Video delivery worked best when participants had a supporting carer, when therapists showed enthusiasm and had an established rapport with the client. Benefits included timeefficiency of sessions, enhancing participants' motivation, caregivers' dementia awareness and therapists' creativity. Limitations included users' poor IT skills and resources. Conclusions: The COVID-19 pandemic required innovative ways of delivering rehabilitation. This study supports that people with dementia can use tele rehab, but success is reliant on having a caregiver and an enthusiastic and known therapist. [ABSTRACT FROM AUTHOR]
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- 2021
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23. New horizons: the management of hypertension in people with dementia
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Jk, Harrison, Van Der Wardt V, Sp, Conroy, Dj, Stott, Dening T, Al, Gordon, Logan P, Tj, Welsh, Jaspal Taggar, Harwood R, and Jr, Gladman
24. Patients' experience with German primary care practices during Covid-19: an interview study.
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Otto D and van der Wardt V
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Background: Patient access to and communication with German primary care practices (PCPs) changed due to Covid-19. Patients had to comply with Covid-19 regulations, which included closed waiting rooms and appointment-based consultations. It is unclear how patients experienced these changes and how the pandemic impacted their primary care attendance., Aim: The aim of the study was to explore how patients, who frequently attended PCPs before the pandemic, perceived primary care during the initial phase of Covid-19 in Germany., Design & Setting: Between January and June 2021, we completed 17 semi-structured interviews. Participants included primary care patients from two regions in Germany who frequently attended their physician before the start of the pandemic., Method: Data were analysed using content analysis., Results: Four interconnected themes emerged in the analysis: 'fear of COVID-19 infection', 'practice organisation', 'information about COVID-19', and 'telemedicine'. Participants were unconcerned about being infected in their practice and mostly agreed with COVID-19 regulations, although waiting outside for their appointment was uncomfortable for some. Participants consulted their primary care physician in relation to different vaccines but felt they were sufficiently informed regarding general information about COVID-19. Views on telemedicine, which was mostly understood as contact via telephone or video call, differed widely, with some participants being very accepting and interested, while others dismissed telemedicine categorically., Conclusion: Participants regarded the new COVID-19 regulations as sensible. Telemedicine using telephone or video call consultations should be further explored under the assumption that this would be acceptable for some but not all patients., (Copyright © 2024, The Authors.)
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- 2024
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25. What are the views of adults with an intellectual disability (AWID), carers and healthcare professionals on a community falls management programme for AWID: a qualitative interview study in the UK.
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Robinson K, Logan P, Tucker C, Finlayson J, van der Wardt V, Kilby A, Knowles S, Vanhegan S, Hodgson S, and Lidstone N
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- Adult, Humans, Fear, Qualitative Research, Delivery of Health Care, United Kingdom, Caregivers, Intellectual Disability
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Objectives: The aim of this study was to refine a draft of the ACTiON FALLS LD programme based on the views of adults with an intellectual disability (AWID), carers and healthcare professionals (HCPs)., Design, Setting and Participants: The semistructured interview study included HCP as well as AWID and carers supporting AWID living in the community. Community settings included sheltered living, supported living, AWID living at home with family carers or independently. The interview study explored the first draft of the ACTiON FALLS LD programme as well as the wider falls management for AWID. Interviews with AWID were developed to include a range of approaches (eg, case studies, pictures) to support inclusive participation. Individual interviews were digitally recorded and transcribed. Researcher notes were used during interviews with AWID. All data were analysed using the principles of framework analysis., Results: 14 HCP, 8 carers and 13 AWID took part in the interview process. Five key themes were identified: programme components, programme design, programme approach, who would use the programme and programme delivery., Conclusions: The views of AWID, HCP and carers showed the need to consider the impact of risk perception, anxiety and fear of falling in the adaption of the ACTiON FALLS programme. The programme needs to be accessible and support the inclusion of AWID in managing falls and ultimately fulfil the requirement for a proactive and educational tool by all., Competing Interests: Competing interests: PL was the lead of the Falls in Care Homes trial and led the development of the ACTiON FALLS programme for community and care home settings, KR was a researcher on the Falls in Care Homes trial., (© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2024
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26. Recommendations for the primary prevention of atherosclerotic cardiovascular disease in primary care: study protocol for a systematic guideline review.
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Schürmann L, Bredehorst M, González-González AI, Muth C, van der Wardt V, Puzhko S, and Haasenritter J
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- Humans, Delivery of Health Care, Risk Factors, Primary Prevention, Primary Health Care, Systematic Reviews as Topic, Cardiovascular Diseases prevention & control, Cardiovascular Diseases drug therapy, Atherosclerosis prevention & control
- Abstract
Introduction: Atherosclerotic cardiovascular disease (ASCVD) was the main cause of death in Germany in 2021, with major risk factors (ie, hypertension, diabetes, dyslipidaemia, obesity and certain lifestyle factors) being highly prevalent. Preventing ASCVD by assessment and modification of these risk factors is an important challenge for general practitioners. This study aims to systematically review and synthesise recent recommendations of national and international guidelines regarding the primary prevention of ASCVD in adults in primary care., Methods and Analysis: We will conduct a systematic review of clinical practice guidelines (CPGs) to evaluate primary prevention strategies for ASCVD. CPGs will be retrieved from MEDLINE and the Turning Research Into Practice database, guideline-specific databases and websites of guidelines-producing societies, with searches limited to publications from 2016 onwards. We will include CPGs in English, Spanish, German or Dutch languages that provide evidence-based recommendations for ASCVD prevention. The study population will include adults without diagnosed ASCVD. Two independent reviewers will assess guideline eligibility and quality by means of the mini-checklist MiChe, and extract study characteristics and relevant recommendations for further consistency analysis. A third reviewer will resolve disagreements. Findings will be presented as a narrative synthesis and in tabular form., Ethics and Dissemination: This review does not require ethical approval. Our systematic review will inform the CPG of the German College of General Practitioners and Family Physicians on the primary prevention of ASCVD. The review results will also be disseminated through publications in peer-reviewed journals and presentations at local, national and international conferences., Prospero Registration Number: CRD42023394605., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2023
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27. Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial.
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Harwood RH, Goldberg SE, Brand A, van Der Wardt V, Booth V, Di Lorito C, Hoare Z, Hancox J, Bajwa R, Burgon C, Howe L, Cowley A, Bramley T, Long A, Lock J, Tucker R, Adams EJ, O'Brien R, Kearney F, Kowalewska K, Godfrey M, Dunlop M, Junaid K, Thacker S, Duff C, Welsh T, Haddon-Silver A, Gladman J, Logan P, Pollock K, Vedhara K, Hood V, Das Nair R, Smith H, Tudor-Edwards R, Hartfiel N, Ezeofor V, Vickers R, Orrell M, and Masud T
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- Adult, Male, Humans, Aged, Aged, 80 and over, Female, Accidental Falls prevention & control, Activities of Daily Living, Fear, Pandemics, Quality of Life, COVID-19, Cognitive Dysfunction therapy, Dementia therapy
- Abstract
Objective: To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care., Design: Randomised controlled trial., Setting: Participants' homes and communities at five sites in the United Kingdom., Participants: 365 adults with early dementia or mild cognitive impairment who were living at home, and family members or carers., Intervention: The intervention, Promoting activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED), was a specially designed, dementia specific, rehabilitation programme focusing on strength, balance, physical activity, and performance of activities of daily living, which was tailored and progressive and addressed risk and the psychological needs of people with dementia. Up to 50 therapy sessions were provided over 12 months. The control group received usual care plus a falls risk assessment. Procedures were adapted during the covid-19 pandemic., Main Outcome Measures: The primary outcome was score on the carer (informant) reported disability assessment for dementia scale 12 months after randomisation. Secondary outcomes were self-reported activities of daily living, physical activity, quality of life, balance, functional mobility, fear of falling, frailty, cognition, mood, carer strain, service use at 12 months, and falls between months 4 and 15., Results: 365 patient participants were randomised, 183 to intervention and 182 to control. The median age of participants was 80 years (range 65-95), median Montreal cognitive assessment score was 20 out of 30 (range 13-26), and 58% (n=210) were men. Intervention participants received a median of 31 therapy sessions (interquartile range 22-40) and reported completing a mean 121 minutes of PrAISED exercise each week. Primary outcome data were available for 149 intervention and 141 control participants. Scores on the disability assessment for dementia scale did not differ between groups: adjusted mean difference -1.3, 95% confidence interval -5.2 to 2.6; Cohen's d effect size -0.06, 95% confidence interval -0.26 to 0.15; P=0.51). Upper 95% confidence intervals excluded small to moderate effects on any of the range of outcome measures. Between months 4 and 15 the intervention group experienced 79 falls and the control group 200 falls (adjusted incidence rate ratio 0.78, 95% confidence interval 0.5 to 1.3; P=0.3)., Conclusion: The intensive PrAISED programme of exercise and functional activity training did not improve activities of daily living, physical activity, or quality of life; reduce falls; or improve any other secondary health status outcomes, despite good uptake. Future research should consider alternative approaches to maintaining ability and wellbeing in people with dementia., Trial Registration: ISRCTN Registry ISRCTN15320670., Competing Interests: Competing interests: All authors have completed the ICMJE uniform disclosure form at www.icmje.org/disclosure-of-interest/ and declare: support from the National Institute for Health and Care Research for the submitted work; no financial relationships with any organisations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work., (© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. No commercial re-use. See rights and permissions. Published by BMJ.)
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- 2023
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28. The facilitators and barriers to improving functional activity and wellbeing in people with dementia: a qualitative study from the process evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED).
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Di Lorito C, van der Wardt V, Pollock K, Howe L, Booth V, Logan P, Gladman J, Masud T, das Nair R, Goldberg S, Vedhara K, O'Brien R, Adams E, Cowley A, Bosco A, Hancox J, Burgon C, Bajwa R, Lock J, Long A, Godfrey M, Dunlop M, and Harwood RH
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- Humans, Activities of Daily Living, Pandemics, Quality of Life, COVID-19, Dementia diagnosis, Dementia therapy
- Abstract
Background: The PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial showed no measurable benefits in activities of daily living, physical activity or quality of life., Objective: To explore participants' responses to PrAISED and explain why an intervention that might be expected to have produced measurable health gains did not do so., Methods: A process evaluation using qualitative methods, comprising interviews and researcher notes., Setting: Data were collected in participants' homes or remotely by telephone or videoconferencing., Sample: A total of 88 interviews were conducted with 44 participants living with dementia (n = 32 intervention group; n = 12 control group) and 39 caregivers. A total of 69 interviews were conducted with 26 therapists., Results: Participants valued the intervention as proactively addressing health issues that were of concern to them, and as a source of social contact, interaction, information and advice. Facilitators to achieving positive outcomes included perceiving progress towards desired goals, positive expectations, therapists' skills and rapport with participants, and caregiver support. Barriers included: cognitive impairment, which prevented independent engagement and carry-over between sessions; chronic physical health problems and intercurrent acute illness and injury; 'tapering' (progressively infrequent supervision intended to help develop habits and independent activity); and the COVID-19 pandemic., Conclusions: Self-directed interventions may not be appropriate in the context of dementia, even in the mild stages of the condition. Dementia-specific factors affected outcomes including caregiver support, rapport with therapists, availability of supervision, motivational factors and the limitations of remote delivery. The effects of cognitive impairment, multimorbidity and frailty overwhelmed any positive impact of the intervention. Maintenance of functional ability is valued, but in the face of inevitable progression of disease, other less tangible outcomes become important, challenging how we frame 'health gain' and trial outcomes., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2023
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29. Physical activity for chronic back pain: qualitative interview study with patients and GPs in German primary care.
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Lindner N, Kornder N, Heisig J, van der Wardt V, and Viniol A
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- Male, Female, Humans, Physician-Patient Relations, Attitude of Health Personnel, Qualitative Research, Exercise, Back Pain therapy, Primary Health Care, General Practitioners
- Abstract
Background: Chronic back pain (CBP) is common among patients in primary care and is associated with significant personal and socioeconomic burden. Research has shown that physical activity (PA) is one of the most effective therapies to reduce pain; however, for GPs it remains challenging to advise and encourage individuals with CBP to exercise regularly., Aim: To provide insight into the views and experiences of PA in individuals with CBP, along with those of GPs, and to reveal the facilitators and barriers to engaging in, and maintaining, PA., Design and Setting: Qualitative semi-structured interviews with individuals with CBP and GPs recruited via the local research practice network (Famprax) in Hessen, western-central Germany between June and December 2021., Method: Interviews were coded separately by consensus and analysed thematically. Findings of the two groups (GPs and patients with CBP) were compared and summarised., Results: A total of 14 patients ( n = 9 females and n = 5 males) and 12 GPs ( n = 5 females and n = 7 males) were interviewed. Opinions and experiences of PA in individuals with CBP were similar both within and across the GP and patient groups. Interviewees expressed their views on internal and external barriers to PA, and provided strategies to address these barriers and concrete recommendations to increase PA. This study revealed a conflicting doctor-patient relationship ranging from paternalistic, to partnership based, to service provision, which could lead to negative perceptions on both sides, such as frustration and stigma., Conclusion: To the best of the authors' knowledge, this is the first qualitative study exploring opinion and experience of PA in individuals with CBP and GPs in parallel. This study reveals a complex doctor- patient relationship and provides an important insight to motivation for, and adherence to, PA in individuals with CBP., (© The Authors.)
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- 2023
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30. Experiences and understanding of apathy in people with neurocognitive disorders and their carers: a qualitative interview study.
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Burgon C, Goldberg S, van der Wardt V, and Harwood RH
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- Humans, Caregivers psychology, Neurocognitive Disorders, Qualitative Research, Apathy, Dementia psychology
- Abstract
Background: apathy, defined as reduced goal-directed activity, interests and emotion, is highly prevalent in neurocognitive disorders (NCDs). Apathy has important consequences for the individuals who experience it and their carers, yet the lived experiences of apathy in this population are not well understood., Objective: to explore how people with NCDs and their carers understand and experience apathy., Method: in-depth semi-structured interviews were conducted in participants' homes. Sixteen people with NCDs (dementia or mild cognitive impairment) and 14 carers, living in four geographical areas of England, took part. Interviews were audio-recorded and transcribed verbatim. Transcripts were analysed using reflexive thematic analysis., Results: four themes were generated: 'Apathy is Poorly Understood'; 'Too much trouble: Mediating Effort and Outcome'; 'Preserving Identity in the Face of Loss of Capability and Autonomy' and 'Opportunity and Exclusion'., Conclusion: apathy is experienced as an understandable response to the everyday struggle people with NCDs face to preserve identity in the face of threats to capability and autonomy and is exacerbated by the lack of support and opportunities. Social and environmental modifications may help reduce apathy. In line with previous qualitative research, this challenges the dominant view of apathy as a neuropsychiatric symptom that excludes the social-environmental context., (© The Author(s) 2023. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For permissions, please email: journals.permissions@oup.com.)
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- 2023
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31. Exploring perceptions regarding family-based delirium management in the intensive care unit.
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Pandhal JK and Van Der Wardt V
- Abstract
Background: Delirium is a common complication in patients treated in the intensive care unit (ICU). Family members can help alleviate patient anxiety and may be able to aid in the management of delirium. This study aimed to explore the perceptions of former ICU patients and their families together, regarding the involvement of family in delirium management., Method: Nine audio-recorded, semi-structured interviews took place with former ICU patients together with a family member. Participants were interviewed after their intensive care follow-up clinic appointment in an East Midlands hospital in England. Interviews were transcribed, coded and analysed using thematic analysis., Results: Three themes were identified: 'understanding about delirium'; 'influencers of delirium management: family and healthcare professionals' and 'family-based delirium care'. Participants expressed that family have a valuable role to play in the management of delirium in the ICU. However, education and guidance is needed to support the family in how delirium can be managed and the current treatment options available. It is important for ICU staff to gain an understanding of the patient's life and personality to personalise delirium management to the needs of the patient and their family., Conclusion: This study found that family presence and knowledge about the patient may be beneficial to delirium management in the ICU. Further research should investigate the effectiveness of the strategies and interventions to understand their influence on delirium management in ICU patients., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Intensive Care Society 2021.)
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- 2022
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32. Impact of COVID-19 lockdown on physical exercise among participants receiving the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) intervention: a repeated measure study.
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Di Lorito C, van der Wardt V, O'Brien R, Gladman J, Masud T, and Harwood RH
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- Aged, Communicable Disease Control, Exercise, Female, Humans, Male, Pandemics, COVID-19, Cognitive Dysfunction therapy, Dementia epidemiology, Dementia therapy
- Abstract
Background: The potential decrease in daily physical activity associated with the COVID-19 pandemic lockdowns may have a negative impact on people living with dementia. Given the limited literature around the effects of home confinement in people living with dementia, this study investigated changes in physical exercise levels of participants in the intervention arm of the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) Randomised Controlled Trial during the first COVID-19 national lockdown. It hypothesised that participants would maintain physical exercise levels., Methods: A repeated measure (three time points) study involving 30 participants (mean age = 78.0 years, 15 male and 15 female, 22 (73.0%) living with their primary caregiver), from four regions in England receiving the PrAISED intervention. PrAISED is an individually tailored intervention of physical exercises and functional activities. Trained therapists deliver therapy sessions over a period of 52 weeks. Study participants received therapy sessions via phone or video calling during the COVID-19 lockdown. This study investigated self-reported minutes of physical exercise recorded on study calendars for the months of February (i.e., baseline - pre-lockdown), May (i.e., T1 - during lockdown), and August (i.e., T2-post-lockdown) 2020., Results: Participants reported a statistically significant increase in activity levels between February and May (Wilcoxon Z = -2.013, p = 0.044) and a statistically significant decrease between May and August (Wilcoxon Z = -2.726, p = 0.004). No significant difference was found in the physical activity levels from pre- to post-lockdown (Wilcoxon Z = 0.485, p = 0.620)., Conclusion: Despite concerns that the restrictions associated with the COVID-19 pandemic might lead to reductions in physical exercise, participants in receipt of the PrAISED intervention increased their amount of physical exercise during lockdown. Our findings support the potential of remote support for people living with dementia to help them maintain physical exercise levels in circumstances where face-to-face service provision is not possible., Trial Registration: The PrAISED trial and process evaluation have received ethical approval number 18/YH/0059 from the Bradford/Leeds Ethics Committee. The Clinical Trial Identifier for PrAISED is: ISRCTN15320670 ( https://doi.org/10.1186/ISRCTN15320670 ). Registration was made on 04/09/2018., (© 2022. The Author(s).)
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- 2022
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33. Rehabilitation care planning on a digital communication platform for patients with a work disability: protocol for the RehaPro-SERVE feasibility study.
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van der Wardt V, Seipp H, Becker A, Maulbecker-Armstrong C, Kraicker R, Schneider A, Heitz A, and Seifart U
- Abstract
Background: Long-term disability to work is a risk factor for a permanent reduction in income. Rehabilitation care can support people to return to work. In Germany, rehabilitation care to return to work is mostly provided in specialised clinics. The aim of the Rehapro-SERVE study is to reduce work disability days by facilitating rehabilitation care planning using a digital communication platform. To investigate the feasibility, we will test the implementation of the digital platform and evaluate the study procedures. The Rehapro-SERVE study is funded by the German Federal Ministry of Labour and Social Affairs (BMAS) (grant number: 661R0053K1)., Method: The feasibility study includes a two-armed unblinded block randomised controlled study (RCT) without follow-up assessments as well as an interview study. Participants for the RCT (n = 16) are primary care patients with a minimum of 4 weeks of absence from work due to musculoskeletal, oncological or psychological conditions and at high risk of early retirement. Eligibility criteria are age 40 to 60 years; minimum of 4 weeks continuous sick leave before recruitment due to musculoskeletal, mental health or oncological conditions; and being at high risk of early retirement. Patients will be recruited from 8 primary care practices in urban and rural areas in Hesse, Germany. Following baseline assessments, patients will be randomised to either digitalised care planning (treatment) or a control group. The digitalised care planning platform will include the patients' primary care physicians, jobcentres and public health physicians to decide on a tailored return-to-work programme. The collaboration will be supported by a case administrator and, if considered beneficial, a social worker for the patient. An interview study will evaluate the acceptability of the study procedures and the intervention., Discussion: The use of a digital communication platform enables stakeholders to exchange information and discuss rehabilitation care planning in a timely fashion. The results of the feasibility study will lead to the adaptation of study procedures for the main study. The results will support the design and conduct of similar studies including digital applications in primary care or across different healthcare settings., Trial Registration: DRKS - German Clinical Trials Register, DRKS00024207 . Registered on 22 March 2021., (© 2021. The Author(s).)
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- 2021
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34. Promoting physical activity in primary care: a systematic review and meta-analysis.
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van der Wardt V, di Lorito C, and Viniol A
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- Humans, Primary Health Care, Exercise, Motivational Interviewing
- Abstract
Background: Promoting physical activity is an important part of patient care in primary care and has been investigated in many studies with a wide range of intervention characteristics, often including external support. It is unclear, however, if promoting physical activity is effective., Aim: To investigate the effectiveness of behaviour change interventions to promote physical activity in primary care., Design and Setting: This is a systematic review and meta-analysis to evaluate physical activity promotion in a primary care setting., Method: EMBASE, MEDLINE, PsycInfo, and the Joanna Briggs Institute Database were searched for 'physical activity', 'interview', 'motivation', 'primary care', and equivalent words to identify randomised controlled trials with physical activity as the outcome at patient level., Results: The review identified 25 eligible studies. The quality appraisal showed that most studies reported insufficient details regarding randomisation, group allocation, blinding, and fidelity of intervention delivery. The included studies reported a wide range of interventions with varying numbers of follow-up visits or phone calls. The overall effect size for interventions with a 6-month follow-up interval was 0.04 (95% confidence interval [CI] = -0.06 to 0.14), and for interventions with a 12-month follow-up interval it was 0.20 (95% CI = 0.04 to 0.36). Only one intervention based on three motivational interviewing sessions achieved a moderate effect., Conclusion: Counselling to promote physical activity in primary care has a limited effect on patients' behaviour and it might not, on its own, be enough to change physical activity behaviour., (© The Authors.)
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- 2021
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35. Tele-Rehabilitation for People with Dementia during the COVID-19 Pandemic: A Case-Study from England.
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Di Lorito C, Duff C, Rogers C, Tuxworth J, Bell J, Fothergill R, Wilkinson L, Bosco A, Howe L, O'Brien R, Godfrey M, Dunlop M, van der Wardt V, Booth V, Logan P, Cowley A, and Harwood RH
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- Caregivers, England epidemiology, Humans, Pandemics, State Medicine, COVID-19, Dementia rehabilitation, Telerehabilitation
- Abstract
Introduction : The Promoting Activity, Independence and Stability in Early Dementia (PrAISED) is delivering an exercise programme for people with dementia. The Lincolnshire partnership National Health Service (NHS) foundation Trust successfully delivered PrAISED through a video-calling platform during the Coronavirus Disease 2019 (COVID-19) pandemic., Methods: This qualitative case-study aimed to identify participants that video delivery worked for, to highlight its benefits and its challenges. Interviews were conducted between May and August 2020 with five participants with dementia and their caregivers ( n = 10), as well as five therapists from the Lincolnshire partnership NHS foundation Trust. The interviews were analysed through thematic analysis., Results: Video delivery worked best when participants had a supporting caregiver and when therapists showed enthusiasm and had an established rapport with the client. Benefits included time efficiency of sessions, enhancing participants' motivation, caregivers' dementia awareness, and therapists' creativity. Limitations included users' poor IT skills and resources., Discussion: The COVID-19 pandemic required innovative ways of delivering rehabilitation. This study supports that people with dementia can use tele-rehabilitation, but success is reliant on having a caregiver and an enthusiastic and known therapist., Competing Interests: The authors declare no conflict of interest.
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- 2021
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36. Measuring Physical Activity Levels in People With Mild Cognitive Impairment or Mild Dementia.
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van der Wardt V, Hancox JE, Burgon C, Bajwa R, Goldberg S, and Harwood RH
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- Aged, Aged, 80 and over, Cognitive Dysfunction diagnosis, Dementia diagnosis, Female, Humans, Male, Middle Aged, Outcome Assessment, Health Care, Qualitative Research, Reproducibility of Results, Accelerometry methods, Aging, Cognitive Dysfunction psychology, Dementia psychology, Exercise physiology, Surveys and Questionnaires standards
- Abstract
Measuring physical activity (PA) in people with mild cognitive impairment or dementia can be difficult. The aim was to investigate the validity and acceptability of three different PA measurement methods. The mixed-method analysis included 49 participants with mild cognitive impairment or dementia, who completed a daily calendar recording PA, the International Physical Activity Questionnaire, and the Longitudinal Aging Study Amsterdam PA Questionnaire, and those who wore a Misfit Shine accelerometer. The quantitative analysis showed equal completion rates for the International Physical Activity Questionnaire and the accelerometer but a lower completion rate for the calendar. Correlations between outcome measures were moderate or strong. The qualitative analysis indicated that all measures were acceptable, though some participants required help to complete the calendars or fasten the accelerometers. The study supported the validity of these methods for people with mild cognitive impairment and mild dementia. Using accelerometers and completing calendars might increase the motivation to be active for some people.
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- 2021
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37. Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology.
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Burgon C, Goldberg SE, van der Wardt V, Brewin C, and Harwood RH
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- Aged, Consensus, Humans, Psychometrics, Reproducibility of Results, Apathy, Dementia diagnosis
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Background: Apathy is highly prevalent in dementia and is also seen in mild cognitive impairment and the general population. Apathy contributes to failure to undertake daily activities and can lead to health problems or crises. It is therefore important to assess apathy. However, there is currently no gold standard measure of apathy. A comprehensive systematic review of the measurement properties of apathy scales is required., Methods: A systematic review was registered with PROSPERO (ID: CRD42018094390). MEDLINE, Embase, PsycINFO, and CINAHL were searched for studies that aimed to develop or assess the validity or reliability of an apathy scale in participants over 65 years, living in the community. A systematic review was conducted in line with the COnsensus-based Standards for the selection of health Measurement INstruments procedure for reviewing patient-reported outcome measures. The studies' risk of bias was assessed, and all relevant measurement properties were assessed for quality. Results were pooled and rated using a modified Grading of Recommendations Assessment, Development, and Evaluation procedure., Results: Fifty-seven publications regarding 18 measures and 39 variations met the eligibility criteria. The methodological quality of individual studies ranged from inadequate to very good and measurement properties ranged from insufficient to sufficient. Similarly, the overall evidence for measurement properties ranged from very low to high quality. The Apathy Evaluation Scale (AES) and Lille Apathy Rating Scale (LARS) had sufficient content validity, reliability, construct validity, and where applicable, structural validity and internal consistency., Conclusion: Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy., (© 2021 S. Karger AG, Basel.)
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- 2021
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38. Exercise interventions for older adults: A systematic review of meta-analyses.
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Di Lorito C, Long A, Byrne A, Harwood RH, Gladman JRF, Schneider S, Logan P, Bosco A, and van der Wardt V
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- Accidental Falls prevention & control, Accidental Falls statistics & numerical data, Activities of Daily Living, Aged, Bone Density, Brain physiology, Cognition Disorders epidemiology, Fear, Health Status, Humans, Meta-Analysis as Topic, Muscle, Skeletal anatomy & histology, Quality of Life, Time Factors, Exercise, Meditation methods, Resistance Training, Video Games
- Abstract
Background: The evidence concerning which physical exercise characteristics are most effective for older adults is fragmented. We aimed to characterize the extent of this diversity and inconsistency and identify future directions for research by undertaking a systematic review of meta-analyses of exercise interventions in older adults., Methods: We searched the Cochrane Database of Systematic Reviews, PsycInfo, MEDLINE, Embase, CINAHL, AMED, SPORTDiscus, and Web of Science for articles that met the following criteria: (1) meta-analyses that synthesized measures of improvement (e.g., effect sizes) on any outcome identified in studies of exercise interventions; (2) participants in the studies meta-analyzed were adults aged 65+ or had a mean age of 70+; (3) meta-analyses that included studies of any type of exercise, including its duration, frequency, intensity, and mode of delivery; (4) interventions that included multiple components (e.g., exercise and cognitive stimulation), with effect sizes that were computed separately for the exercise component; and (5) meta-analyses that were published in any year or language. The characteristics of the reviews, of the interventions, and of the parameters improved through exercise were reported through narrative synthesis. Identification of the interventions linked to the largest improvements was carried out by identifying the highest values for improvement recorded across the reviews. The study included 56 meta-analyses that were heterogeneous in relation to population, sample size, settings, outcomes, and intervention characteristics., Results: The largest effect sizes for improvement were found for resistance training, meditative movement interventions, and exercise-based active videogames., Conclusion: The review identified important gaps in research, including a lack of studies investigating the benefits of group interventions, the characteristics of professionals delivering the interventions associated with better outcomes, and the impact of motivational strategies and of significant others (e.g., carers) on intervention delivery and outcomes., Competing Interests: Competing interests The authors declare that they have no competing interests., (Copyright © 2020. Production and hosting by Elsevier B.V.)
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- 2021
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39. Mixed-Methods Study on Caregiver Strain, Quality of Life, and Perceived Health.
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Di Lorito C, Bosco A, Godfrey M, Dunlop M, Lock J, Pollock K, Harwood RH, and van der Wardt V
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- Aged, Aged, 80 and over, Anxiety Disorders psychology, Counseling, Humans, Male, Surveys and Questionnaires, Activities of Daily Living psychology, Anxiety psychology, Caregivers psychology, Depression psychology, Quality of Life
- Abstract
Background: Caring for someone with dementia is associated with negative and positive experiences. There is little evidence based on large datasets., Objective: To present data around the experience of caring for someone with dementia, to identify support (emotional and practical) needs, and inform future service provision., Methods: A mixed-methods study embedded in the Promoting Activity, Independence and Stability in Early Dementia (PrAISED) Randomized Controlled Trial. We administered questionnaires on strain, quality of life (QoL), and perceived health to 301 caregivers and assessment of cognitive performance, depression, anxiety, and disability in activities of daily living to 301 participants with dementia. Data were analyzed through descriptive and modelling statistics. A subsample of 20 patient-caregiver dyads were qualitatively interviewed. Data around caregivers' experience of providing care were extrapolated and analyzed through inductive thematic analysis., Results: There were significant negative associations between caregiver strain and QoL (p < 0.01) and between caregiver age and QoL (p < 0.01), and significant positive associations between caregiver strain and disability (p < 0.01), cognitive impairment (p < 0.01), depression (p < 0.05), and anxiety of the person with dementia (p < 0.05). Older caregivers reported a lack of support, reinforced by their reluctance to seek help. All caregivers reported contradictory emotions associated with caring and accumulation of strain over time., Conclusion: While there is recognition that it is essential to support caregivers, dedicated intervention programs, and support strategies to respond to the needs of older caregivers are still needed.
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- 2021
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40. Protocol for the process evaluation of the Promoting Activity, Independence and Stability in Early Dementia (PrAISED), following changes required by the COVID-19 pandemic.
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Di Lorito C, Bosco A, Goldberg SE, Nair R, O'Brien R, Howe L, van der Wardt V, Pollock K, Booth V, Logan P, Godfrey M, Dunlop M, Horne J, and Harwood RH
- Subjects
- Activities of Daily Living, Betacoronavirus, COVID-19, Caregivers, Exercise Therapy, Female, Home Care Services, Humans, Male, Research Design, SARS-CoV-2, Social Isolation, Cognitive Dysfunction therapy, Coronavirus Infections epidemiology, Coronavirus Infections virology, Dementia therapy, Exercise, Health Promotion, Independent Living, Pandemics, Pneumonia, Viral epidemiology, Pneumonia, Viral virology, Process Assessment, Health Care
- Abstract
Introduction: The Promoting Activity, Independence and Stability in Early Dementia (PrAISED) randomised controlled trial (RCT) is evaluating a home-based, face-to-face, individually tailored, activity and exercise programme for people living with dementia. Social distancing requirements following the COVID-19 pandemic necessitated rapid changes to intervention delivery., Methods and Analysis: A mixed-methods process evaluation will investigate how the changes were implemented and the impact that these have on participants' experience. An implementation study will investigate how the intervention was delivered during the pandemic. A study on the mechanisms of impact and context will investigate how these changes were experienced by the PrAISED participants, their carers and the therapists delivering the intervention. The study will commence in May 2020., Ethics and Dissemination: The PrAISED RCT and process evaluation have received ethical approval number 18/YH/0059. The PrAISED process evaluation will enable us to understand how distancing and isolation affected participants, their activity and exercise routines and whether the therapy programme could be continued with remote support. This will be valuable both in explaining trial results and also contribute to understanding and designing new ways of delivering home-based services and rehabilitation interventions for people with dementia and their carers., Trial Registration Number: ISRCTN15320670; Pre-results., Competing Interests: Competing interests: None declared., (© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ.)
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- 2020
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41. Physical activity engagement strategies in people with mild cognitive impairment or dementia - a focus group study.
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van der Wardt V, Hancox J, Pollock K, Logan P, Vedhara K, and Harwood RH
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- Caregivers, Exercise, Focus Groups, Humans, Cognitive Dysfunction, Dementia
- Abstract
Objective: This focus group study aimed to explore how to motivate people with mild cognitive impairment (MCI) or dementia and their carers to engage in exercise and physical activity. Methods: Four focus groups were conducted with six people with MCI or dementia, three carers and four clinicians (nurse, occupational therapist, physiotherapists). A thematic analysis of the data was undertaken. Results: Five main themes were identified: 'memory problems', 'self-motivation', 'external motivation', 'design of activities' and 'barriers'. Participants viewed exercise positively but emphasised that it needed to fit into their daily routine. Goal-setting was seen as helpful by some participants but others saw this as a source of potential failure. Enjoyment was seen as key to engagement. Conclusion: Exercise and physical activity interventions need an individualised approach to engage people with MCI or dementia, with a positive emphasis on enjoyment. Goal-setting should be used with caution in this group of people.
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- 2020
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42. The Impact of a Dementia-Friendly Exercise Class on People Living with Dementia: A Mixed-Methods Study.
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Long A, Di Lorito C, Logan P, Booth V, Howe L, Hood-Moore V, and van der Wardt V
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- Aged, Caregivers, Cognition, Cohort Studies, Female, Humans, Loneliness, Male, Prospective Studies, Dementia rehabilitation, Exercise
- Abstract
Exercise has multiple benefits for people living with dementia. A programme of group exercise classes for people with dementia and their family carers has been established in a University sports centre. This study aims to explore the impact of this programme on participants with dementia and their carers. A mixed-methods design including a prospective, repeated measures cohort study followed by focus groups was employed. Physiological and cognitive outcome measures were repeated at baseline and three months in a cohort of people with dementia attending a group exercise class. Focus groups on the participants' experiences and their perceptions of the impact of the exercise class on their lives were then conducted. The results were analysed and mapped on a model, to illustrate the components that most likely promote participation. Sixteen participants (n = 8 with dementia, and n = 8 carers) were recruited, and completed both baseline and follow up assessments. Positive mean differences were found in physical activity (4.44), loneliness (1.75), mood (1.33) and cognition (1.13). Ten participants were included in the focus groups, which found that accessibility of the exercise venue, opportunities for socialisation and staff who were experienced working with people living with dementia were key to participants reporting benefits. The four key themes from the focus group data were synthesised to produce a model outlining the components that might generate a positive impact of the exercise classes and promote participation. Exercise classes for people with dementia can be delivered with success in novel environments such as University sports centres. There is some indication of improvement over a short period of time. The model derived from this study will inform strategies to promote attendance at dementia-friendly exercise classes.
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- 2020
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43. Adherence to exercise interventions in older people with mild cognitive impairment and dementia: A systematic review and meta-analysis.
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Di Lorito C, Bosco A, Booth V, Goldberg S, Harwood RH, and Van der Wardt V
- Abstract
Adherence to physical exercise is associated with multiple benefits in people with mild cognitive impairment (MCI) and dementia. Given the gap in research, this systematic literature review aimed to determine in the context of exercise intervention studies for people with MCI and dementia: 1. How adherence is defined, monitored and recorded; 2. Adherence rates; 3. Attrition, compliance and adverse events and 4. Intervention characteristics associated with adherence. Embase, Medline, PsychInfo, SPORTDiscus, AMED, CINAHL and the International Bibliography of Social Sciences were searched in November 2018. The data were analyzed through descriptive and correlation/inferential statistics. Forty-one studies were included, 34 involving participants with dementia (n = 2149) and seven participants with MCI (n = 970). Half of the studies operationally defined adherence. Mean adherence rate was 70% [CI, 69-73%]. Adherence was significantly associated with endurance/resistance training, and interventions not including walking. The review found a lack of consistency around reporting of adherence and of key variables mediating adherence, including compliance, attrition and adverse events. Further research using more reliable measures is needed to confirm whether a correlation exists between length of interventions and adherence in participants with MCI and dementia and to identify the factors or strategies that mediate adherence in this population. Relevant implications for practice include a consideration in the development of new interventions of elements associated with higher adherence in this review, such as endurance/resistance training, and the provision of exercise in group formats., (© 2020 The Author(s).)
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- 2020
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44. Adding to the knowledge on Patient and Public Involvement: Reflections from an experience of co-research with carers of people with dementia.
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Di Lorito C, Godfrey M, Dunlop M, Bosco A, Pollock K, van der Wardt V, and Harwood RH
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- Humans, Patient Participation, Qualitative Research, Research Personnel, Caregivers, Dementia
- Abstract
Background: Patient and Public Involvement (PPI) in research ensures that publicly funded research reflects the priorities of the people who will be affected by its results. Co-research, a branch of PPI, is equal partnership between academic researchers and members of the public, who steer and conduct research together., Objectives: To propose a model for good practice in co-researching with carers of people with dementia, by reporting and synthesizing the personal reflections of the academic and lay researchers around the methodological issues, benefits, and challenges of co-research., Design: An academic researcher and two lay researchers with lived experience of caring with someone with dementia collaborated in all stages of a qualitative research study, including development of the research protocol and topic guide, data collection, analysis and synthesis, and dissemination of findings. Throughout the study, the academic and lay researchers annotated reflections of their experience in personal diaries. Data from the diaries were synthesized and mapped out in a model for good practice in co-research., Results: Co-research yielded benefits for all those involved and on research outputs. There were practicalities and challenges that required extra resources, in order to make the involvement of lay researchers meaningful and effective., Discussion: The model for good practice illustrates overarching and stage-specific guidelines, which can inform researchers and members of the public wishing to undertake good practice in co-research., (© 2020 The Authors Health Expectations published by John Wiley & Sons Ltd.)
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- 2020
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45. External Validation of the ' PHYT in Dementia' , a Theoretical Model Promoting Physical Activity in People with Dementia.
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Di Lorito C, Bosco A, Pollock K, H Harwood R, das Nair R, Logan P, Goldberg S, Booth V, Vedhara K, Godfrey M, Dunlop M, and van der Wardt V
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- Caregivers, Humans, Male, Models, Theoretical, Motivation, Program Evaluation, Dementia therapy, Exercise, Health Promotion methods
- Abstract
Physical activity is beneficial for people with dementia. We previously developed a theoretical model to explain behaviour change in physical activity in dementia (PHYT-in-dementia). This study aimed to externally validate the model. Validation occurred through the process evaluation of a programme promoting activity in people with dementia (PrAISED 2). Twenty participants with dementia and their carers were interviewed to investigate their experience of the programme. The data were analysed through content analysis. The original constructs of the model were used as initial codes and new codes were generated, if elicited from the data. The constructs were also ranked, based on their frequency in the interviews. All of the original model constructs were validated and two novel constructs created: 'personal history' and 'information/knowledge' . Certain constructs (e.g., support) were more frequently mentioned than others (e.g., personal beliefs). We suggested modifications and integrated them into a revised model. The PHYT-in-dementia recognised that dementia has an impact on motivation to initiate and maintain behaviour change over time. The model advocates that interventions adopt a more holistic approach than traditional behaviour change strategies. The suggested revisions require further validation to accurately predict behaviour change in physical activity in people with dementia.
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- 2020
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46. A randomised controlled trial of an exercise intervention promoting activity, independence and stability in older adults with mild cognitive impairment and early dementia (PrAISED) - A Protocol.
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Bajwa RK, Goldberg SE, Van der Wardt V, Burgon C, Di Lorito C, Godfrey M, Dunlop M, Logan P, Masud T, Gladman J, Smith H, Hood-Moore V, Booth V, Das Nair R, Pollock K, Vedhara K, Edwards RT, Jones C, Hoare Z, Brand A, and Harwood RH
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Male, Accidental Falls prevention & control, Caregivers, Cost-Benefit Analysis, Delivery of Health Care methods, Exercise, Feasibility Studies, Follow-Up Studies, Multicenter Studies as Topic, Postural Balance, Pragmatic Clinical Trials as Topic, Quality of Life, Cognitive Dysfunction therapy, Dementia therapy, Exercise Therapy methods, Independent Living psychology
- Abstract
Background: People with dementia progressively lose cognitive and functional abilities. Interventions promoting exercise and activity may slow decline. We developed a novel intervention to promote activity and independence and prevent falls in people with mild cognitive impairment (MCI) or early dementia. We successfully undertook a feasibility randomised controlled trial (RCT) to refine the intervention and research delivery. We are now delivering a multi-centred RCT to evaluate its clinical and cost-effectiveness., Methods: We will recruit 368 people with MCI or early dementia (Montreal Cognitive Assessment score 13-25) and a family member or carer from memory assessment clinics, other community health or social care venues or an online register (the National Institute for Health Research Join Dementia Research). Participants will be randomised to an individually tailored activity and exercise programme delivered using motivational theory to promote adherence and continued engagement, with up to 50 supervised sessions over one year, or a brief falls prevention assessment (control). The intervention will be delivered in participants' homes by trained physiotherapists, occupational therapists and therapy assistants. We will measure disabilities in activities of daily living, physical activity, balance, cognition, mood, quality of life, falls, carer strain and healthcare and social care use. We will use a mixed methods approach to conduct a process evaluation to assess staff training and delivery of the intervention, and to identify individual- and context-level mechanisms affecting intervention engagement and activity maintenance. We will undertake a health economic evaluation to determine if the intervention is cost-effective., Discussion: We describe the protocol for a multi-centre RCT that will evaluate the clinical and cost-effectiveness of a therapy programme designed to promote activity and independence amongst people living with dementia., Trial Registration: ISRCTN, ISRCTN15320670. Registered on 4 September 2018.
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- 2019
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47. Promoting activity, Independence and stability in early dementia (PrAISED): a, multisite, randomised controlled, feasibility trial.
- Author
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Goldberg SE, van der Wardt V, Brand A, Burgon C, Bajwa R, Hoare Z, Logan PL, and Harwood RH
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- Accidental Falls prevention & control, Aged, Aged, 80 and over, Caregivers psychology, Exercise Therapy methods, Feasibility Studies, Female, Humans, Independent Living psychology, Male, Outcome Assessment, Health Care methods, Single-Blind Method, Surveys and Questionnaires, Activities of Daily Living psychology, Dementia psychology, Dementia therapy, Exercise physiology, Exercise psychology, Postural Balance physiology
- Abstract
Background: We tested the feasibility of delivering and evaluating a complex therapy intervention which aimed to promote activity and independence for people with early dementia (PrAISED). Feasibility questions were on: recruitment, randomisation, intervention delivery, adherence and withdrawals, level of supervision required, adverse events, data collection and sample size assumptions., Methods: We conducted a three-arm, multi-site, single-blind, randomised controlled feasibility trial. Eligibility criteria were aged 65 years or older, diagnosed mild dementia or mild cognitive impairment, able to walk without human help, and communicate in English, no co-morbidities that prevented participation in cognitive assessment and capacity to give consent. Participants were recruited from Memory Assessment Service clinics and the 'Join Dementia Research' register. Patient participants were randomised 1:1:1 to a high intensity supervision PrAISED intervention, moderate intensity supervision PrAISED intervention or brief falls prevention assessment and advice (control). The PrAISED intervention aimed for participants to complete three hours of PrAISED exercises a week for 12 months. It included individualised activity and exercise plans and supervised exercises with regular re-assessment and progression, and was delivered by occupational therapists, physiotherapists and rehabilitation support workers. Primary efficacy outcome was the Disability Assessment for Dementia (DAD), measured after 12 months. Secondary outcomes included physical activity, quality of life, mood, cognition, strength, balance, rate of falls, frailty and carer strain. Falls and activity were ascertained by monthly diary., Results: Between September 2016 and March 2017 we recruited 60 patient participants and 54 carer participants from two sites. Forty-nine patient participants completed a follow-up interview. Feasibility outcomes were mostly satisfactory, including recruitment and retention, intervention delivery and data completeness for most scales used. We could not maintain blinding of researchers at follow-up and experienced difficulties collecting data using some questionnaires and devices. Participants only completed a mean 77 (moderate supervision) and 71 (high supervision) minutes per week of PrAISED exercises over 12 months. We recorded 19 adverse events, none serious and related to the intervention., Conclusion: We conclude that with some adjustments to the trial protocol, it is feasible to deliver the PrAISED intervention and conduct a trial., Trial Registration: ClinicalTrials.gov: NCT02874300 (first posted 22nd August 2016), ISRCTN: 10550694 (date assigned 31st August 2016).
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- 2019
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48. Factors influencing adherence to home-based strength and balance exercises among older adults with mild cognitive impairment and early dementia: Promoting Activity, Independence and Stability in Early Dementia (PrAISED).
- Author
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Hancox JE, van der Wardt V, Pollock K, Booth V, Vedhara K, and Harwood RH
- Subjects
- Aged, Aged, 80 and over, Cognitive Dysfunction physiopathology, Cognitive Dysfunction psychology, Dementia physiopathology, Dementia psychology, Exercise physiology, Exercise psychology, Exercise Therapy psychology, Feasibility Studies, Female, Humans, Male, Patient Compliance psychology, Postural Balance physiology, Resistance Training methods, Treatment Outcome, Cognitive Dysfunction therapy, Dementia therapy, Exercise Therapy methods
- Abstract
Background: Older adults with dementia are at a high risk of losing abilities and of accidental falls. Promoting Activity, Independence and Stability in Early Dementia (PrAISED) is a 12-month person-centred exercise and activity programme which aims to increase activity and independence whilst reducing falls in people with early dementia. In this patient group, as well as many others, poor adherence to exercise interventions can undermine treatment effectiveness. We aimed to explore patterns of barriers and facilitators influencing PrAISED participants' adherence to home-based strength and balance exercises., Methods: Participants were a subsample of 20 individuals with mild cognitive impairment or early dementia and their carer(s) taking part in the PrAISED programme. Participants (with the support of a carer where necessary) kept a daily exercise diary. Participants' adherence were categorised based upon reported number of times a week they undertook the PrAISED strength and balance exercises over a 4 month period (<3 times a week = low adherence, 3-4 = meeting adherence expectations, >5 = exceeding adherence expectations). Semi-structured interviews were conducted in month 4 of the PrAISED programme to explore barriers and facilitators to adherence. A mixture of deductive and inductive thematic analysis was employed with themes categorised using the Theoretical Domains Framework., Findings: Participants completed on average 98 minutes of home-based strength and balance exercises per week, 3.8 sessions per week, for an average of 24 minutes per session. Five participants were categorised as exceeding adherence expectations, 7 as meeting adherence expectations, and 8 as low adherers. Analysis of interview data based on self-reported adherence revealed six interacting themes: 1) routine, 2) practical and emotional support, 3) memory support, 4) purpose, 5) past experiences of sport and exercise, and 6) belief in and experience of benefits., Conclusions: Identifiable cognitive, psychological, and practical factors influence adherence to exercise, and should be addressed in future development of interventions with this population., Competing Interests: The authors have declared that no competing interests exist.
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- 2019
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49. Protocol for the process evaluation of the promoting activity, independence and stability in early dementia and mild cognitive impairment (PrAISED 2) randomised controlled trial.
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Di Lorito C, Pollock K, Harwood R, Nair RD, Logan P, Goldberg S, Booth V, Godfrey M, Dunlop M, and Van Der Wardt V
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- Humans, Cognitive Dysfunction, Dementia, Independent Living
- Abstract
Introduction: We are conducting a randomised controlled trial (Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment - PrAISED 2) to test the effectiveness of an intervention to promote activity and independence amongst people with mild cognitive impairment and early dementia. A process evaluation is needed to determine how the intervention works. This protocol outlines the rationale, aims, objectives and methods of the process evaluation., Methods: The process evaluation will use a mixed-methods design and comprise two studies: An implementation study, examining the process through which PrAISED 2 is delivered, and a study on the mechanisms of impact and context, focussing on the mediating mechanisms that contribute to study outcomes. Integration of separate analyses of quantitative and qualitative data will provide a holistic view of how the PrAISED 2 intervention works., Conclusion: Results from this process evaluation will further the understanding of the factors that can impinge on the success of complex interventions. This will represent invaluable information for researchers undertaking further research around behaviour change among people with cognitive impairment and dementia., (Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.)
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- 2019
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50. A scoping review of behaviour change theories in adults without dementia to adapt and develop the 'PHYT in dementia', a model promoting physical activity in people with dementia.
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Di Lorito C, Pollock K, Harwood R, das Nair R, Logan P, Goldberg S, Booth V, Vedhara K, and Van Der Wardt V
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- Humans, Quality of Life, Behavior, Dementia psychology, Exercise, Models, Theoretical
- Abstract
Introduction: Research has established that exercise and physical activity can improve executive functioning, independence and quality of life in people with dementia. A dedicated theory explaining behaviour change in relation to physical activity in people with dementia does not exist. We aimed to develop a theoretical model which can be used to inform effective interventions to promote physical activity in people with dementia., Methods: There were five phases: 1. A search of the literature to identify theories which have been used to explain behaviour change in relation to physical activity in adult populations without a diagnosis of dementia; 2. Description of the theories (and sub-theories) and their main constructs; 3. Synthesis of the constructs; 4. Adaptation of the constructs to dementia; 5. Development and explanation of a model for physical activity in people with dementia (the 'PHYT in dementia')., Results: We identified nine theories used to explain behaviour change in relation to physical activity in adult populations without a diagnosis of dementia. Through our synthesis, we identified nine umbrella constructs. We integrated three more dementia-relevant constructs and developed the 'PHYT in dementia'. The model was explained by providing a practical example of its application., Discussion: Based on a scoping review of behaviour change theories in adults without dementia and following adaptation of the constructs from these theories to dementia, we derived a new theoretical model, the 'PHYT in dementia', which includes both individual-level and environment-level constructs. The model needs to be tested empirically, which our research team will do in the process evaluation of the Promoting Activity, Independence and Stability in Early Dementia and Mild Cognitive Impairment (PrAISED 2) study. Results from field-testing will inform refinement of the model., (Copyright © 2019. Published by Elsevier B.V.)
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- 2019
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