1. Practical Advice for Primary Care Clinicians on the Safe and Effective Use of Vortioxetine for Patients with Major Depressive Disorder (MDD)
- Author
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Montano CB, Jackson WC, Vanacore D, and Weisler RH
- Subjects
antidepressant ,measurement-guided care ,shared decision-making ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
C Brendan Montano,1,2 W Clay Jackson,3,4 Denise Vanacore,5 Richard H Weisler6,7 1Montano Wellness LLC, Cromwell, CT, USA; 2Department of Family Medicine, University of Connecticut Medical School, Farmington, CT, USA; 3Department of Psychiatry and Family Medicine, West Cancer Center, Germantown, TN, USA; 4Department of Psychiatry and Family Medicine, University of Tennessee College of Medicine, Memphis, TN, USA; 5Department of Nursing, Messiah University, Mechanicsburg, PA, USA; 6Richard H. Weisler MD, P.A. & Associates, Raleigh, NC, USA; 7Department of Psychiatry, Duke University and the University of North Carolina at Chapel Hill, Chapel Hill, NC, USACorrespondence: C Brendan Montano, Montano Wellness LLC, 160 West St., Ste. 1A, Cromwell, CT, 06416, USA, Tel +1 860-632-0144, Fax +1 860-632-7882, Email docmontano@aol.comAbstract: Primary care clinicians have a vital role to play in the diagnosis and management of patients with major depressive disorder (MDD). This includes screening for MDD as well as identifying other possible psychiatric disorders including bipolar disorder and/or other comorbidities. Once MDD is confirmed, partnering with patients in the shared decision-making process while considering different treatment options and best management of MDD over the course of their illness is recommended. Vortioxetine has been approved for the treatment of adults with MDD since 2013, and subsequent US label updates indicate that vortioxetine may be particularly beneficial for specific populations of patients with MDD, including those with treatment-emergent sexual dysfunction and patients experiencing certain cognitive symptoms. Given these recent label updates, this prescribing guide for vortioxetine aims to provide clear and practical guidance for primary care clinicians on the safe and effective use of vortioxetine for the treatment of MDD, including how to identify appropriate patients for treatment.Keywords: antidepressant, measurement-guided care, shared decision-making
- Published
- 2022