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Background: The clinical profile of COVID-19-positive pregnant mothers and their outcome has not been studied in Mizoram. Aims and Objectives: The objectives was to study the clinical profile of COVID-19-positive pregnant mothers and also to study the positivity rate among the babies born to those pregnant mothers. Materials and Methods: This study was a retrospective cohort of COVID-19-positive pregnant mothers who were admitted in a tertiary care center in Mizoram from July 2020 to September 2021. The data were collected from the case sheets of the patients retrospectively. The babies were also tested for COVID-19 after 24 h after birth by rapid antigen test (RAT). P<0.05 was considered statistically significant. Data analysis was done by coGuide Statistics software, Version 1.0. Results: Out of 81 COVID-19-positive pregnant mothers, majority 56 (69.14%) were in the age group 19-25 years. Only 6 (7.41%) were vaccinated. The most common symptoms observed were fever 35 (43.21%) followed by cough 28 (34.57%). Sixty-five (80.25%) were full term at the time of admission and 36 (44.44%) were primigravida. The mode of delivery was full-term cesarean section 55 (67.90%), term normal vaginal delivery 21 (25.93%), hysterotomy 3 (3.7%), abortion 1 (1.23%), and pre-term vaginal delivery 1 (1.23%). The mortality among pregnant mothers was 3 (3.70%). The positivity rate for babies tested by RAT was 2 (2.47%). Conclusion: The mortality among pregnant mothers was 3.70% and the COVID-19 positivity rate among newborn babies was 2.47%. [ABSTRACT FROM AUTHOR]

The severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) that causes the COVID-19 pandemic has affected every household of the remotest part of North East India, Mizoram. The pregnant women do not have a higher chance of getting infected, yet the infection seems to be more severe. We are reporting five cases of maternal death and two cases of maternal near miss in ZMC of Mizoram. Case 1 to 5 were maternal death due to COVID-19. All of them were multigravida within the age group of 27–41 years with a period of gestation 24–37 weeks. The presenting complaints were fever and cough more than 3 days with an investigation report revealing raised C-reactive protein (CRP) and severe pneumonia. Case 6 (Near miss) was 20 years, primigravida at term pregnancy in labor with a history of fever for 2 days with an investigation report revealing raised CRP and severe pneumonia, the baby was delivered asphyxiated and died. Case 7 (Near miss) was 17 years old primigravida at term pregnancy admitted as asymptomatic COVID-19 positive, elective caesarean section was done for Obstetrics indication, the patient later developed fever and moderate pneumonia on 5 days of hospitalization, she also developed eclampsia on 7th hospital day, she survived after intensive care in the intensive care unit. [ABSTRACT FROM AUTHOR]