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201 results on '"Vanwijck, R."'

11. ONLINE MUTATION REPORT

Author

Ghassibé, M, Revencu, N, Bayet, B, Gillerot, Y, Vanwijck, R, Verellen-Dumoulin, C, and Vikkula, M

Published
2004

20. IRF6 Screening of Syndromic and a priori Non-Syndromic Cleft Lip and Palate Patients: Identification of a New Type of Minor VWS Sign

Author

Desmyter, L., primary, Ghassibe, M., additional, Revencu, N., additional, Boute, O., additional, Lees, M., additional, François, G., additional, Verellen-Dumoulin, C., additional, Sznajer, Y., additional, Moncla, A., additional, Benateau, H., additional, Claes, K., additional, Devriendt, K., additional, Mathieu, M., additional, Van Maldergem, L., additional, Addor, M.-C., additional, Drouin-Garraud, V., additional, Mortier, G., additional, Bouma, M., additional, Dieux-Coeslier, A., additional, Genevieve, D., additional, Goldenberg, A., additional, Gozu, A., additional, Makrythanasis, P., additional, McEntagart, M., additional, Sanchez, A., additional, Vilain, C., additional, Vermeer, S., additional, Connell, F., additional, Verheij, J., additional, Manouvrier, S., additional, Pierquin, G., additional, Odent, S., additional, Holder-Espinasse, M., additional, Vincent-Delorme, C., additional, Gillerot, Y., additional, Vanwijck, R., additional, Bayet, B., additional, and Vikkula, M., additional

Published
2010
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30. Wound Bed Preparation by Hydrosurgery.

Author

Eisenmann-Klein, Marita, Neuhann-Lorenz, Constance, Gonzalez Rodriguez de Azero, M., and Vanwijck, R.

Abstract

A wound bed may be prepared by various non-surgical d'ebridements: autolytic facilitated by interactive dressings, larval therapy using sterile maggots and enzymatic débridements using collagenases. These are all effective in selected wounds but tend to be slow. [ABSTRACT FROM AUTHOR]

Published
2008
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38. Management of cleft lip and palate.

Author

Vanwijck, R., Bayet, B., Deggouj, N., Siciliano, S., and Bousaba, S.

Subjects
*CLEFT lip, *CLEFT palate
Abstract

Since 1987, we chosed a neonatal repair of the cleft lip and nose and closure of the cleft palate at 3 months of age. Ventilation tubes are systematically inserted in the drums at time of palatoplasty. Alveolar clefts are grafted when canine erupts. Secondary correction, which might be early, are scheduled according to functional, aesthetic or psychological demands. A interdisciplinary follow-up by a stable and united team is essential for an adequate management of sequels. [Copyright &y& Elsevier]

Published
2002

41. Endoscopic harvest of the medial gastrocnemius muscle flap: a cadaveric study

Author

Basmacioglu, P., Vanwijck, R., Claveria, G., Danino, A., Mamlouk, K., Revol, M., and Servant, J.M.

Abstract

The aim of our study was to prove that endoscopic-assisted harvest of the medial gastrocnemius muscleis as effective as the conventional technique. We performed endoscopic dissection on 10 fresh human cadavers, and found that the medial gastrocnemius muscle was easily harvested through a minor donor-site incision, because of its topography and constant dominant proximal vascular pedicle. The operative technique is described.

Published
2002
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42. Orofacial clefting: Update on the role of genetics

Author

Ghassibe, M., Bayet, B., Revencu, N., Desmyter, L., Verellen-Dumoulin, C., Gillerot, Y., Deggouj, N., Vanwijck, R., Miikka Vikkula, Pellerin, Ph, Boute, O., Lees, M., Devriendt, K., Mortier, G., Maldergem, L., Claes, I. K., Vilain, C., Mcentagart, M. E., Bouma, M., Geneviève, D., Sanchez, A., and Gözü, A.

43. Tumor regressions observed in patients with metastatic melanoma treated with an antigenic peptide encoded by gene MAGE-3 and presented by HLA-A1

Author

Marchand, M., Baren, N., Weynants, P., Brichard, V., Dreno, B., Tessier, Mh, Rankin, E., Parmiani, G., Arienti, F., Humblet, Y., Bourlond, A., Vanwijck, R., Lienard, D., Beauduin, M., Dietrich, Py, Russo, V., Kerger, J., Giuseppe Masucci, Jager, E., Greve, J., Atzpodien, J., Brasseur, F., Coulie, Pg, Bruggen, P., Boon, T., Medical Imaging and Physical Sciences, and Vrije Universiteit Brussel

Subjects
Adult, Male, Antigen Presentation, Remission Induction, Middle Aged, Neoplasm Proteins, Antigens, Neoplasm, Genetic Code, Disease Progression, Humans, Female, Immunotherapy, Melanoma, HLA-A1 Antigen, Aged
Abstract

Thirty-nine tumor-bearing patients with metastatic melanoma were treated with 3 subcutaneous injections of the MAGE-3.A1 peptide at monthly intervals. No significant toxicity was observed. Of the 25 patients who received the complete treatment, 7 displayed significant tumor regressions. All but one of these regressions involved cutaneous metastases. Three regressions were complete and 2 of these led to a disease-free state, which persisted for more than 2 years after the beginning of treatment. No evidence for a cytolytic T lymphocyte (CTL) response was found in the blood of the 4 patients who were analyzed, including 2 who displayed complete tumor regression. Our results suggest that injection of the MAGE-3.A1 peptide induced tumor regression in a significant number of the patients, even though no massive CTL response was produced.

48. [Update to the recommendations for management of melanoma stages I to III].

Author

Guillot B, Dalac S, Denis MG, Dupuy A, Emile JF, De La Fouchardière A, Hindie E, Jouary T, Lassau N, Mirabel X, Piperno Neumann S, De Raucourt S, and Vanwijck R

Subjects
Biomarkers, Tumor analysis, Chemotherapy, Adjuvant, Diagnostic Imaging, Genetic Counseling, Humans, Immunohistochemistry, Lymphatic Metastasis, Margins of Excision, Neoplasm Staging, Radiotherapy, Adjuvant, Melanoma pathology, Melanoma therapy, Skin Neoplasms pathology, Skin Neoplasms therapy
Abstract

As knowledge continues to develop, regular updates are necessary concerning recommendations for practice. The recommendations for the management of melanoma stages I to III were drawn up in 2005. At the request of the Société Française de Dermatologie, they have now been updated using the methodology for recommendations proposed by the Haute Autorité de Santé. In practice, the principal recommendations are as follows: for staging, it is recommended that the 7th edition of AJCC be used. The maximum excision margins have been reduced to 2cm. Regarding adjuvant therapy, the place of interferon has been reduced and no validated emerging medication has yet been identified. Radiotherapy may be considered for patients in stage III at high risk of relapse. The sentinel lymph node technique remains an option. Initial examination includes routine ultrasound as of stage II, with other examinations being optional in stages IIC and III. A shorter strict follow-up period (3years) is recommended for patients, but with greater emphasis on imaging., (Copyright © 2016 Elsevier Masson SAS. All rights reserved.)

Published
2016
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49. [Guidelines for stage I to III melanoma].

Author

Guillot B, Dalac S, Denis M, Dupuy A, Emile JF, De La Fouchardiere A, Hindie E, Jouary T, Lassau N, Mirabel X, Piperno Neumann S, De Raucourt S, and Vanwijck R

Subjects
Antineoplastic Agents therapeutic use, Chemotherapy, Adjuvant, Female, Genotype, Humans, Male, Margins of Excision, Melanoma classification, Melanoma diagnosis, Melanoma pathology, Neoplasm Staging, Proto-Oncogene Proteins B-raf genetics, Sentinel Lymph Node pathology, Sentinel Lymph Node Biopsy, Skin Neoplasms classification, Skin Neoplasms diagnosis, Skin Neoplasms pathology, Melanoma therapy, Skin Neoplasms therapy
Published
2016
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50. Autologous Adipose Stromal Cells Seeded onto a Human Collagen Matrix for Dermal Regeneration in Chronic Wounds: Clinical Proof of Concept.

Author

Lafosse A, Desmet C, Aouassar N, André W, Hanet MS, Beauloye C, Vanwijck R, Poirel HA, Gallez B, and Dufrane D

Subjects
Animals, Chronic Disease, Coculture Techniques methods, Humans, Rats, Rats, Sprague-Dawley, Regeneration physiology, Sensitivity and Specificity, Skin, Artificial, Transplantation, Autologous, Ultrasonography, Wound Healing physiology, Adipocytes transplantation, Biological Dressings statistics & numerical data, Collagen physiology, Neovascularization, Physiologic physiology, Stromal Cells transplantation, Wounds and Injuries diagnostic imaging
Abstract

Background: Nonhealing wounds are unable to integrate skin autografts by avascular and fibrotic dermal tissue. Adipose-derived stromal cells can improve the local environment of the wound bed by angiogenesis and immunomodulation. This work aimed to develop a biological dressing made of adipose-derived stromal cells onto a human acellular collagen matrix., Methods: Adipose-derived stromal cells were isolated from human adipose tissue (n = 8). In vitro, the genetic stability during early and late passages (1, 4, 10, and 16) and vascular endothelial growth factor (VEGF) secretion were assessed. Adipose-derived stromal cell adhesion and spreading on collagen matrix were preliminarily studied. In vivo tumorigenicity, angiogenesis, and tissue oxygenation were assessed after implantation of the construct in nude rats (n = 10). The biological dressing was manufactured and implanted in three patients with chronic wounds., Results: In vitro, aneuploidies, but no clonal transformation, were detected up to late cellular passages. VEGF was secreted more during hypoxia (0.1% oxygen) than during normoxia (21% oxygen). Adipose-derived stromal cells can adhere and spread on the scaffold within 18 to 20 days. No tumor development occurred 3 months after implantation in immunocompromised rats. Vessel counts and tissue oxygenation were higher after adipose-derived stromal cell implantation. In patients, granulation tissue was found (276 percent of vessel density), followed by epithelialization or split-thickness skin engraftment up to 22 months after implantation., Conclusions: Implantation of adipose-derived stromal cells seeded onto human acellular collagen matrix (biological dressing) represents a promising therapy for nonhealing wounds, offering improvement in dermal angiogenesis and remodeling. This therapy using autologous stromal cells is safe, without significant genetic alterations after in vitro expansion.

Published
2015
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