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20 results on '"Vasicova, Pavla"'

1. Frentizole derivatives with mTOR inhibiting and senomorphic properties

Author

Chrienova, Zofia, Rysanek, David, Novak, Josef, Vasicova, Pavla, Oleksak, Patrik, Andrys, Rudolf, Skarka, Adam, Dumanovic, Jelena, Milovanovic, Zoran, Jacevic, Vesna, Chvojkova, Marketa, Holubova, Kristina, Vales, Karel, Skoupilova, Veronika, Valko, Marian, Jomova, Klaudia, Alomar, Suliman Y., Botelho, Fernanda D., Franca, Tanos C.C., Kuca, Kamil, Hodny, Zdenek, and Nepovimova, Eugenie

Published
2023
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4. Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Author

Chrienova, Zofia, primary, Rysanek, David, additional, Oleksak, Patrik, additional, Stary, Dorota, additional, Bajda, Marek, additional, Reinis, Milan, additional, Mikyskova, Romana, additional, Novotny, Ondrej, additional, Andrys, Rudolf, additional, Skarka, Adam, additional, Vasicova, Pavla, additional, Novak, Josef, additional, Valis, Martin, additional, Kuca, Kamil, additional, Hodny, Zdenek, additional, and Nepovimova, Eugenie, additional

Published
2022
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8. Front Cover: Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity (J. Biophotonics 12/2019)

Author

Salajkova, Sarka, primary, Sramek, Michal, additional, Malinak, David, additional, Havel, Filip, additional, Musilek, Kamil, additional, Benkova, Marketa, additional, Soukup, Ondrej, additional, Vasicova, Pavla, additional, Prchal, Lukas, additional, Dolezal, Rafael, additional, Hodny, Zdenek, additional, Bartek, Jiri, additional, Zarska, Monika, additional, and Kuca, Kamil, additional

Published
2019
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9. Analysis of the Corynebacterium glutamicum dapA promoter

Author

Vasicova, Pavla, Patek, Miroslav, Nesvera, Jan, Sahm, Hermann, and Eikmanns, Bernhard

Subjects
Promoters (Genetics) -- Research, Gene mutations -- Analysis, Bacterial genetics -- Physiological aspects, Biological sciences
Abstract

Results indicate that an extended -10 region and a six thymidine stretch at -55 to -50 positions are important for the promoter function of the Corynebacterium glutamicum promoter P-dapA.

Published
1999

11. Highly hydrophilic cationic gold nanorods stabilized by novel quaternary ammonium surfactant with negligible cytotoxicity

Author

Salajkova, Sarka, primary, Sramek, Michal, additional, Malinak, David, additional, Havel, Filip, additional, Musilek, Kamil, additional, Benkova, Marketa, additional, Soukup, Ondrej, additional, Vasicova, Pavla, additional, Prchal, Lukas, additional, Dolezal, Rafael, additional, Hodny, Zdenek, additional, Bartek, Jiri, additional, Zarska, Monika, additional, and Kuca, Kamil, additional

Published
2019
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12. Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence

Author

Mrazkova, Blanka, primary, Dzijak, Rastislav, additional, Imrichova, Terezie, additional, Kyjacova, Lenka, additional, Barath, Peter, additional, Dzubak, Petr, additional, Holub, Dusan, additional, Hajduch, Marian, additional, Nahacka, Zuzana, additional, Andera, Ladislav, additional, Holicek, Petr, additional, Vasicova, Pavla, additional, Sapega, Olena, additional, Bartek, Jiri, additional, and Hodny, Zdenek, additional

Published
2018
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13. Microbial Cell / Formaldehyde fixation is detrimental to actin cables in glucose-depleted S. cerevisiae cells

Author

Vasicova, Pavla, Rinnerthaler, Mark, Haskova, Danusa, Novakova, Lenka, Malcova, Ivana, Breitenbach, Michael, and Hasek, Jiri

Subjects
Actin patches, Abp140-GFP, macromolecular substances, yeast, Actin cables, Abp1-RFP
Abstract

Actin filaments form cortical patches and emanating cables in fermenting cells of Saccharomyces cerevisiae. This pattern has been shown to be depolarized in glucose-depleted cells after formaldehyde fixation and staining with rhodamine-tagged phalloidin. Loss of actin cables in mother cells was remarkable. Here we extend our knowledge on actin in live glucose-depleted cells co-expressing the marker of actin patches (Abp1-RFP) with the marker of actin cables (Abp140-GFP). Glucose depletion resulted in appearance of actin patches also in mother cells. However, even after 80 min of glucose deprivation these cells showed a clear network of actin cables labeled with Abp140-GFP in contrast to previously published data. In live cells with a mitochondrial dysfunction (rho0 cells), glucose depletion resulted in almost immediate appearance of Abp140-GFP foci partially overlapping with Abp1-RFP patches in mother cells. Residual actin cables were clustered in patch-associated bundles. A similar overlapping “patchy” pattern of both actin markers was observed upon treatment of glucose-deprived rho+ cells with FCCP (the inhibitor of oxidative phosphorylation) and upon treatment with formaldehyde. While the formaldehyde-targeted process stays unknown, our results indicate that published data on yeast actin cytoskeleton obtained from glucose-depleted cells after fixation should be considered with caution. P26713 (VLID)2689913

Published
2016

20. Interferon gamma/NADPH oxidase defense system in immunity and cancer.

Author

Hodny, Zdenek, Reinis, Milan, Hubackova, Sona, Vasicova, Pavla, and Bartek, Jiri

Subjects
CANCER immunology, CELLULAR immunity, INTERFERON gamma, NADPH oxidase, ANTINEOPLASTIC agents, REACTIVE oxygen species
Abstract

As a part of cellular pathogen defense, IFNγ triggers induction of NADPH oxidase NOX2, which produces superoxide into phagosomes of immune cells. Recent data show that a similar mechanism can also operate in IFNγ-mediated anticancer control. IFNγ is capable of inducing expression of constitutively active NADPH oxidase NOX4 in tumor cells leading to generation of reactive oxygen species (ROS) damaging DNA, activation of DNA damage response and cell cycle arrest/premature cellular senescence. [ABSTRACT FROM AUTHOR]

Published
2016
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