106 results on '"Vasquez K"'
Search Results
2. STATE OF THE CLIMATE IN 2017
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BLUNDEN, J., HARTFIELD, G., ARNDT, D. S., DUNN, R. J. H., TYE, M. R., BLENKINSOP, S., DONAT, M., DURRE, I., ZIESE, M., COOPER, O. R., HEMMING, D. L., ABERNETHY, R., ARMITAGE, C., BOLMGREN, K., MYNENI, R., PARK, T., RICHARDSON, A. D., RUTISHÄUSER, T., SPARKS, T. H., THACKERAY, S. J., EAKIN, C. M., LIU, G., GOMEZ, A. M., DE LA COUR, J. L., HERON, S. F., SKIRVING, W. J., GEIGER, E. F., MARSH, B. L., TIRAK, K. V., STRONG, A. E., YOON, H., WIDLANSKY, M. J., THOMPSON, P. R., KLOTZBACH, P. J., VELDEN, C. S., ROTH, D. M., NIELSEN-GAMMON, J. W., OSBORNE, E., CRONIN, T., FARMER, J., BEHE, C., DANIEL, R., YORK, A., BHATT, U., THOMAN, R., ZIEL, R., SWART, S., CAMPBELL, E. C., HEUZÉ, C. H., JOHNSON, K., LIESER, J. L., MASSOM, R., MAZLOFF, M., MEREDITH, M., REID, P., SALLÉE, J.-B., STAMMERJOHN, S., MARTINEZ-SÁNCHEZ, O., TAKAHASHI, K., ALIAGA-NESTARES, V., AVALOS, G., BOUCHON, M., CASTRO, A., CRUZADO, L., DEWITTE, B., GUTIÉRREZ, D., LAVADO-CASIMIRO, W., MARENGO, J., MARTÍNEZ, A. G., MOSQUERA-VÁSQUEZ, K., QUISPE, N., ZHU, Z., LI, T., TOGAWA, H., TOBIN, S., and JACOBS, S. J.
- Published
- 2018
3. Enhancing sustainable water management: utilizing UAV-based NIR/SWIR hyperspectral imaging to evaluate grapevine water status in a variably irrigated vineyard
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Laroche-Pinel, E., primary, Vasquez, K., additional, Partida, G., additional, and Brillante, L., additional
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- 2024
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4. Transitioning from laboratory research to real-world application: encouraging results in the practical utilization of hyperspectral images for field detection of grapevine viruses
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Laroche-Pinel, E., primary, Sawyer, E., additional, Corrales, B., additional, Singh, K., additional, Vasquez, K., additional, Cooper, M.L., additional, Fuchs, M., additional, and Brillante, L., additional
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- 2024
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5. Grape composition assessment using NIR/SWIR hyperspectral imagery acquired from a UTV
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Abioye, A.E., primary, Laroche-Pinel, E., additional, Sams, B., additional, Corales, B., additional, Vasquez, K., additional, Cianciola, V., additional, and Brillante, L., additional
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- 2024
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6. Extracts of Chilean native fruits inhibit oxidative stress, inflammation and insulin-resistance linked to the pathogenic interaction between adipocytes and macrophages
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Reyes-Farias, M., Vasquez, K., Fuentes, F., Ovalle-Marin, A., Parra-Ruiz, C., Zamora, O., Pino, M.T., Quitral, V., Jimenez, P., Garcia, L., and Garcia-Diaz, D.F.
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- 2016
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7. [Published] - Love is Not Colorblind: An Investigation of the Racial Hierarchy of Mate Preferences
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Li J, Yim S, Javidi D, Khalil L, Wu J, Disler G, Venegas-Vasquez K, Hensley M, Saraf Y, Haydel J, Willis J, Wang Z, Rodriguez M, and Simanian A
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Racial hierarchy ,Sociology ,Social psychology - Abstract
[Please see published material] - Not my type is the usual invocation when rejecting potential lovers who don’t align with the racial hierarchy of mating preferences. The largely unchallenged norm of interracial intimacy aversion, particularly how the desire for some racial groups and rejection of others reinforces existing racial inequities, is inconsistent with the blanket notion of greater interracial acceptance. Our investigation assessed the openness of monoracial and multiracial individuals to form interracial romantic relationships. We partially replicated an interracial mate preference known as the Multiracial Dividend Effect, finding that most monoracial groups equally preferred same-race lovers and interracially dating multiracials, and they preferred interracially dating someone multiracial over any monoracial group, whereas Multiracials were more open to interracially dating any monoracial group than monoracials were to interracially dating each other. In addition, Hispanic-White and East Asian-White multiracials were more open to interracially dating White individuals than their respective monoracial in-group members, and East Asian-White multiracials were more open to interracially dating all monoracial minority groups than monoracial East Asian participants. Finally, half-White multiracials are more likely to be in partial-racial couples (e.g., former President of the United States Barack Obama is Black-White multiracial and the former First Lady of the United States, Michelle Obama, is Black) whereas interminority multiracials are more likely to be in 100% interracial/non-overlapping couples (e.g., Vice President of the United States Kamala Harris is interminority Tamil Indian and Black whereas the Second Gentleman of the United States, Doug Emhoff, is White).
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- 2020
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8. 91726 Screening for Obesity related renal damage in adolescent women - Body Surface area matters
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Bielopolski, D., primary, Singh, N., additional, Bentur, O.S., additional, Renert-Yuval, Y., additional, MacArthur, R., additional, Vasquez, K., additional, Moftah, D.S., additional, Vaughan, R.D., additional, Kost, R.G., additional, and Tobin, J.N., additional
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- 2021
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9. Sulforaphane induces phase II detoxication enzymes in mouse skin and prevents mutagenesis induced by a mustard gas analog
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Abel, E. L., Boulware, S., Fields, T., McIvor, E., Powell, K. L., DiGiovanni, J., Vasquez, K. M., and MacLeod, M. C.
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- 2013
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10. Maqui, Calafate, and Blueberry fruits extracts treatments suppress the pathogenic interaction amongst human adipocytes and macrophages
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Ovalle-Marin, A., primary, Reyes-Farias, M., additional, Vasquez, K., additional, Parra-Ruiz, C., additional, Quitral, V., additional, Jimenez, P., additional, Garcia, L., additional, Ramirez, L.A., additional, Quezada, J., additional, Gonzalez-Muniesa, P., additional, and Garcia-Diaz, D.F., additional
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- 2020
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11. A polyphenol-rich Calafate (Berberis microphylla) extract rescues glucose tolerance in mice fed with cafeteria diet
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Soto-Covasich, J., primary, Reyes-Farias, M., additional, Torres, R.F., additional, Vasquez, K., additional, Duarte, L., additional, Quezada, J., additional, Jimenez, P., additional, Pino, M.T., additional, Garcia-Nannig, L., additional, Mercado, L., additional, and Garcia-Diaz, D.F., additional
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- 2020
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12. Lose to win: a national workplace weight management programme: T5:OS2.5
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Amin, H, Vasquez, K R, Thilagaratnam, S, Choo, L, and Tseng, P
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- 2010
13. High Mobility Group Protein B1 Affects Mutagenesis and Cell Death Caused by UVC and Psoralen-lnduced DNA Damage.: 17
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Lange, S and Vasquez, K.
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- 2007
14. The Mismatch Repair Proteins, MSH2 and MLH1, Contribute Differently to Cellular Responses to DNA Interstrand Crosslinks in Human Cells.: 5
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Wu, Q and Vasquez, K.
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- 2007
15. 235 No Association of Oxandrolone Administration and the Development or Severity of Heterotopic Ossification Following Burn Injury
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Thorpe, C R, primary, Ulcer Ozgurel, S, additional, Simko, L C, additional, Goldstein, R, additional, Grant, G G, additional, Pagani, C, additional, Hwang, C, additional, Vasquez, K, additional, Sorkin, M, additional, Goverman, J, additional, Sheridan, R L, additional, Friedstat, J, additional, Schulz, J T, additional, Levi, B, additional, Schneider, J C, additional, and Ryan, C M, additional
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- 2019
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16. Puerto Rican Plain Pigeon food intake in a captive breeding program
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Aviles-Vasquez, I.I. and Aviles-Vasquez, K.
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Captive wild animals -- Breeding ,Pigeons -- Food and nutrition -- Behavior -- Observations -- Research ,Captive wild birds -- Food and nutrition -- Behavior -- Observations -- Research ,Animal feeding behavior -- Research -- Behavior ,Environmental issues ,Zoology and wildlife conservation ,Observations ,Research ,Behavior ,Food and nutrition - Abstract
The Puerto Rican Plain Pigeon (Columba inornata wetmorei) is one of the endangered species in the island of Puerto Rico. A captive breeding program was established from 1984 to 2001 [...]
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- 2004
17. P6244Prediction of long-term mortality through the combination of the GRACE and CRUSADE scales in patients with acute coronary syndrome
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Santos-Martinez, S, primary, Vidal-Burdeus, M, additional, Quintern, V, additional, Peiro, O M, additional, Gonzalez-Del-Hoyo, M I, additional, Dominguez-Benito, F, additional, Vasquez, K, additional, Romeu, A, additional, Ferrero-Guillem, M, additional, and Bardaji, A, additional
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- 2018
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18. Innovative simulation models for cervical cancer training in low-resource settings
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Parra, S.G., primary, Brigham, C., additional, Diaz, C., additional, Mia, W., additional, Mnewa, M., additional, Sonka, T., additional, Vasquez, K., additional, Schmeler, K.M., additional, and Richards-Kortum, R., additional
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- 2018
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19. The 2002/2003 El Nino: Equatorial waves sequence and their impact on sea surface temperature
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Mosquera-Vasquez, K., Dewitte, B., Illig, S., Takahashi, K., Garric, G., Laboratoire d'études en Géophysique et océanographie spatiales (LEGOS), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Instituto Geofísico del Perú (IGP), Echanges Côte-Large (ECOLA), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Mercator Océan, Société Civile CNRS Ifremer IRD Météo-France SHOM, Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), and Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)
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WARM POOL ,[SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere ,purl.org/pe-repo/ocde/ford#1.05.09 [http] ,Equatorial waves ,TOPEX/POSEIDON ,CIRCULATION ,Physics::Geophysics ,purl.org/pe-repo/ocde/ford#1.05.00 [http] ,EVENTS ,MODEL ,purl.org/pe-repo/ocde/ford#1.05.11 [http] ,VARIABILITY ,purl.org/pe-repo/ocde/ford#1.05.10 [http] ,OCEAN ,El Niño ,Warm water volume ,TROPICAL PACIFIC ,ENSO ,Physics::Atmospheric and Oceanic Physics - Abstract
ISI Document Delivery No.: 129JU Times Cited: 1 Cited Reference Count: 38 Cited References: Ashok K, 2007, J GEOPHYS RES-OCEANS, V112, DOI 10.1029/2006JC003798 Belmadani A, 2010, J CLIMATE, V23, P3181, DOI 10.1175/2010JCLI2830.1 BLUMENTHAL MB, 1989, J PHYS OCEANOGR, V19, P815, DOI 10.1175/1520-0485(1989)0192.0.CO;2 Bosc C, 2008, J GEOPHYS RES-OCEANS, V113, DOI 10.1029/2007JC004613 BUSALACCHI AJ, 1988, J PHYS OCEANOGR, V18, P801, DOI 10.1175/1520-0485(1988)0182.0.CO;2 Chelton DB, 2001, J CLIMATE, V14, P1479, DOI 10.1175/1520-0442(2001)0142.0.CO;2 CLARKE AJ, 1991, J GEOPHYS RES-OCEANS, V96, P10731, DOI 10.1029/91JC00933 Dewitte B, 2011, J GEOPHYS RES-OCEANS, V116, DOI 10.1029/2010JC006495 Dewitte B, 2012, CLIM DYNAM, V38, P2275, DOI 10.1007/s00382-011-1215-x Dewitte B, 2003, J GEOPHYS RES-OCEANS, V108, DOI 10.1029/2002JC001362 Ducet N, 2000, J GEOPHYS RES-OCEANS, V105, P19477, DOI 10.1029/2000JC900063 Fedorov AV, 2001, J CLIMATE, V14, P3086, DOI 10.1175/1520-0442(2001)0142.0.CO;2 Garric G., 2008, 235 MERC Gentemann CL, 2003, GEOPHYS RES LETT, V30, DOI 10.1029/2002GL016291 HAYES SP, 1991, J GEOPHYS RES-OCEANS, V96, P10553, DOI 10.1029/91JC00942 Jin FF, 1997, J ATMOS SCI, V54, P811, DOI 10.1175/1520-0469(1997)0542.0.CO;2 Kug JS, 2009, J CLIMATE, V22, P1499, DOI 10.1175/2008JCLI2624.1 Kug JS, 2010, J CLIMATE, V23, P1226, DOI 10.1175/2009JCLI3293.1 Kim W, 2011, GEOPHYS RES LETT, V38, DOI 10.1029/2011GL048521 Lee T, 2010, GEOPHYS RES LETT, V37, DOI 10.1029/2010GL044007 Lengaigne M, 2012, CLIM DYNAM, V38, P1031, DOI 10.1007/s00382-011-1051-z Le Traon PY, 1998, J GEOPHYS RES-OCEANS, V103, P8045, DOI 10.1029/97JC01917 Levitus S, 1998, WORLD OCEAN DATABASE Madec G., 1998, OPA 8 1 OCEAN GEN CI McPhaden MJ, 1998, J GEOPHYS RES-OCEANS, V103, P14169, DOI 10.1029/97JC02906 McPhaden MJ, 2011, GEOPHYS RES LETT, V38, DOI 10.1029/2011GL048275 McPhaden MJ, 2012, GEOPHYS RES LETT, V39, DOI 10.1029/2012GL051826 McPhaden MJ, 2004, B AM METEOROL SOC, V85, P677, DOI 10.1175/BAMS-85-5-677 Meinen CS, 2000, J CLIMATE, V13, P3551, DOI 10.1175/1520-0442(2000)0132.0.CO;2 FU LL, 1994, J GEOPHYS RES-OCEANS, V99, P24369, DOI 10.1029/94JC01761 Rayner NA, 2003, J GEOPHYS RES-ATMOS, V108, DOI 10.1029/2002JD002670 Takahashi K, 2011, GEOPHYS RES LETT, V38, DOI 10.1029/2011GL047364 Wang WM, 1999, J PHYS OCEANOGR, V29, P1812, DOI 10.1175/1520-0485(1999)0292.0.CO;2 Wentz FJ, 2000, SCIENCE, V288, P847, DOI 10.1126/science.288.5467.847 Yeh SW, 2009, NATURE, V461, P511, DOI 10.1038/nature08316 Yu JY, 2010, GEOPHYS RES LETT, V37, DOI 10.1029/2010GL042810 Yu JY, 2011, THEOR APPL CLIMATOL, V103, P337, DOI 10.1007/s00704-010-0307-6 ZEBIAK SE, 1987, MON WEATHER REV, V115, P2262, DOI 10.1175/1520-0493(1987)1152.0.CO;2 Mosquera-Vasquez, K. Dewitte, B. Illig, S. Takahashi, K. Garric, G. Takahashi, Ken/G-5321-2010 Takahashi, Ken/0000-0003-3670-2939 Institut de Recherche pour le Developpement (IRD) K. Mosquera-Vasquez benefited from a Ph.D. scholarship received from Institut de Recherche pour le Developpement (IRD). The authors also thank the two anonymous reviewers for their constructive comments. This work is part of the projects of the special agreement between IRD and IGP (2011-2013). 1 AMER GEOPHYSICAL UNION WASHINGTON J GEOPHYS RES-OCEANS; The recent decades have experienced changes in the characteristics of the El Nino phenomenon, with in particular an increased occurrence of so-called Modoki or Central Pacific El Ninos. Here the 2002/2003 El Nino, characterized as a Central Pacific El Nino, is studied from an Ocean General Circulation Model simulation. The focus is on the sequence of equatorial waves and their impact on zonal and vertical advection. The wave amplitude according to the most energetic baroclinic modes are first estimated, which allows inferring the sequence of the intraseasonal equatorial Kelvin (IKW) and Rossby (IRW) waves. It is shown that energetic downwelling IKWs, forced in the western-central Pacific, crossed the equatorial Pacific. Reflections of IKWs into IRWs onto the zonally varying thermocline and eastern boundary are also observed. A simplified heat budget of the surface layer is then carried out to infer the dominant processes at work during the evolution of this event focusing on the wave-induced advection terms. The results indicate that the warming phase (April-November 2002) is mainly controlled by zonal advection of mean temperature (accounted for by IKWs and locally wind-driven current) and by vertical advection in the eastern Pacific. The cooling phase (December 2002 to April 2003) is dominated by a reduction in solar radiation and the IRW-induced zonal advection of mean temperature respectively in the central and eastern equatorial Pacific. The recharge-discharge process is also showed to be at work with the recharge (discharge) process operating mainly through the second (first) baroclinic mode.
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- 2013
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20. Plasma protein and supplemental isoleucine in milk replacers for dairy calves.
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Vasquez, K. M., Morrison, S. Y., Campbell, J. M., and Drackley, J. K.
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CATTLE feeding & feeds , *CALVES , *CATTLE nutrition , *BLOOD proteins , *ISOLEUCINE , *DRY matter in animal nutrition , *BODY weight - Abstract
We measured the effects of milk replacers containing 0, 33, 66, or 100% of the total replaceable whey protein as bovine plasma protein (PP), without or with Ile supplementation, on the intake, growth, and health of 124 male Holstein calves for 35 d. Milk replacers were formulated to contain 18% crude protein and 20% fat, with contents of Lys and Met equalized. When fed to calves at 1.5% of body weight (dry matter basis) under thermoneutral conditions, diets were predicted to allow average daily gains of 0.55 kg/d based on metabolizable energy or 0.40 kg/d based on apparent digestible protein. Protein supply was more limiting than energy so that differences in protein use could be detected. Dry matter intakes decreased with increased PP, irrespective of Ile supplementation. Final body weights decreased linearly with increasing PP, regardless of Ile supplementation. Average daily gain tended to be affected in a quadratic manner as PP increased, either with or without Ile supplementation; average daily gain and gain-feed ratio were greatest for calves fed diets containing 33% PP and lowest for calves fed 100% PP. The analyzed Lys content in the milk replacers was variable compared with formulated values, and this may have affected growth results. However, the gain-Lys ratio was affected by an interaction of the linear effect of increasing PP with Ile supplementation: it decreased with increasing PP but was improved by supplementation with Ile for calves fed 100% PP. Body measurements decreased with increasing PP inclusion; only decreased heart girth was reversed with Ile supplementation. The lowest and highest inclusion of PP, regardless of Ile supplementation, decreased the occurrence of scours compared with the control diet (all whey protein). Calves fed the lowest and highest PP without Ile supplementation also had fewer total days of scours in the first 21 d. In addition, calves fed 100% PP without supplementation of Ile had fewer days of medication compared with the control diet. Even at the highest PP inclusion, average daily gain was minimally affected if Ile was supplemented. Growth rates, gainfeed ratio, and gain-Lys ratio were decreased at higher PP inclusion, but Ile overcame part of the reduction in gain-Lys ratio for 100% PP. Additional titration studies will have to be conducted to determine optimal PP inclusion rates, with a focus on supplementation of potentially limiting essential AA, as well as effects at higher growth rates. [ABSTRACT FROM AUTHOR]
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- 2017
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21. DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells
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Jain, A., primary, Bacolla, A., additional, del Mundo, I. M., additional, Zhao, J., additional, Wang, G., additional, and Vasquez, K. M., additional
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- 2013
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22. Targeted gene conversion induced by triplex-directed psoralen interstrand crosslinks in mammalian cells
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Liu, Y., primary, Nairn, R. S., additional, and Vasquez, K. M., additional
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- 2009
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23. Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease
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Christensen, L. A., primary, Wang, H., additional, Van Houten, B., additional, and Vasquez, K. M., additional
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- 2008
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24. Processing of triplex-directed psoralen DNA interstrand crosslinks by recombination mechanisms
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Liu, Y., primary, Nairn, R. S., additional, and Vasquez, K. M., additional
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- 2008
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25. Inhibitory effect of a short Z-DNA forming sequence on transcription elongation by T7 RNA polymerase
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Ditlevson, J. V., primary, Tornaletti, S., additional, Belotserkovskii, B. P., additional, Teijeiro, V., additional, Wang, G., additional, Vasquez, K. M., additional, and Hanawalt, P. C., additional
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- 2008
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26. Strategies to Working With Institutional Review Boards in Indian Country
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Macedo, J, primary and Vasquez, K, additional
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- 2006
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27. Ionic levels of the gallbladder bile of some teleosts from the Rio Negro, Amazon
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Baldisserotto, B., primary, Lopez-Vasquez, K., additional, Silva, L. V. F., additional, Golombieski, J. I., additional, and Val, A. L., additional
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- 2004
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28. Chromosomal mutations induced by triplex-forming oligonucleotides in mammalian cells
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Vasquez, K., primary
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- 1999
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29. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity
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Finch, R. A., Liu, M. C., Grill, S. P., Rose, W. C., Loomis, R., Vasquez, K. M., Cheng, Y. C., and Sartorelli, A. C.
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- 2000
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30. Expectations of intergroup empathy bias emerge by early childhood.
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Tompkins R, Vasquez K, Gerdin E, Dunham Y, and Liberman Z
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- Humans, Male, Female, Child, Child, Preschool, Adult, Group Processes, Social Perception, Young Adult, Child Development physiology, Empathy
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Across two preregistered studies with children (3-12-year-olds; N = 356) and adults ( N = 262) from the United States, we find robust expectations for intergroup empathic biases. Participants predicted that people would feel better about ingroup fortunes than outgroup fortunes and worse about ingroup misfortunes than outgroup misfortunes. Expectations of empathic bias were stronger when there was animosity and weaker when there was fondness between groups. The largest developmental differences emerged in participants' expectations about how others feel about outgroup misfortunes, particularly when there was intergroup animosity. Whereas young children (3-5-year-olds) generally expected people to feel empathy for the outgroup (regardless of the relationship between the groups), older children (9-12-year-olds) and adults expected Schadenfreude (feeling good when an outgroup experiences a misfortune) when the groups disliked one another. Overall, expectations of empathic biases emerge early but may be weaker when there are positive intergroup relationships. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
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- 2024
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31. Parental financial support and family emotional support to young adults during COVID-19: A help or a hindrance?
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Serido J, Li L, Vosylis R, Vasquez K, Sorgente A, Lep Ž, Fonseca G, Crespo C, Relvas AP, Zupančič M, and Lanz M
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The present study focuses on the role of family support to young adult children during COVID-19 in ameliorating the negative financial impact of the pandemic. Guided by the Conservation of Resources (COR) Theory of stress and coping, we conceptualize the negative financial impact due to COVID-19 as a source of financial stress that would be associated with lower levels of both financial wellbeing and positive outlook of young adults. We rely on data collected from a multinational sample of young adults (ages 18-30) from six countries (China, Italy, Lithuania, Portugal, Slovenia, US; N = 2102) over a 3-month period (July 2020-September 2020). We tested the potential effects of two types of support (i.e., parental financial support and family emotional support) using path analysis. While we find a consistent positive association between family emotional support and both financial wellbeing and positive outlook, we also find a consistent negative association between parental financial support and financial wellbeing, and a nonsignificant or negative association (Lithuania only) with a positive outlook. The significant interaction between COVID-19 financial impact and family emotional support on young adults' positive outlook reveals that the benefit of family emotional support is more evident when the negative financial impact is low or moderate. We discuss the implications of these findings in assisting young adults to cope with financial disruptions., (© 2024 The Author(s). Family Process published by Wiley Periodicals LLC on behalf of Family Process Institute.)
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- 2024
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32. The nonmeek inherit the earth: Children generalize dominance, but not submissiveness.
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Hok H, Vasquez K, Barakzai A, and Shaw A
- Subjects
- Humans, Child, Male, Female, Child, Preschool, Generalization, Psychological physiology, Social Perception, Social Dominance, Child Development physiology
- Abstract
Children and even infants have clear intuitions about power early in development; they can infer who is dominant and subordinate from observing a single interaction. However, it is unclear what children infer about each individual's status from these interactions-do they think dominants and subordinates will maintain their status when interacting with novel partners? In three experiments, we investigate this question. Children (4- to 10-year-olds, N = 365) heard stories about a dominant and subordinate agent and predicted the dominant or subordinate agent's behavior with a novel agent. In all studies, we found that 7- to 10-year-olds generalized dominance, thinking the dominant would again be dominant or "in charge," both for social power (e.g., granting permission) in Study 1 and physical dominance (e.g., a fistfight) in Studies 2 and 3. Furthermore, although they believed dominant agents would win dominance contests (fistfights), they did not believe they would win contests unrelated to dominance (math contests). Younger children did not generalize social power (Study 1) but did generalize physical dominance (Studies 2 and 3). However, even for physical dominance, their generalizations were less selective (i.e., they believed the dominant would win fistfights and math contests). Notably, neither age group generalized an agent's submissiveness in any of the studies-they did not believe a subordinate agent would again be subordinate when paired with a novel partner. We discuss how these results extend past work on children's developing intuitions about dominance and prompt deeper questions about the inferences children draw from dominance interactions. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
- Published
- 2024
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33. Update to: Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore.
- Author
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Lim JT, Mailepessov D, Chong CS, Chang CC, Dickens B, Lai YL, Deng L, Lee C, Tan LY, Chain G, Ho SH, Zulkifli MF, Liew J, Vasquez K, Lee V, Wong JCC, Sim S, Tan CH, and Ng LC
- Subjects
- Animals, Singapore epidemiology, Male, Humans, Incidence, Mosquito Control methods, Female, Pest Control, Biological methods, Dengue prevention & control, Dengue epidemiology, Dengue transmission, Wolbachia, Aedes microbiology, Aedes virology, Mosquito Vectors microbiology, Mosquito Vectors virology, Randomized Controlled Trials as Topic
- Abstract
Background: This trial is a parallel, two-arm, non-blinded cluster randomised controlled trial that is under way in Singapore, with the aim of measuring the efficacy of male Wolbachia-infected Aedes aegypti deployments in reducing dengue incidence in an endemic setting with all four dengue serotypes in circulation. The trial commenced in July 2022 and is expected to conclude in September 2024. The original study protocol was published in December 2022. Here, we describe amendments that have been made to the study protocol since commencement of the trial., Methods: The key protocol amendments are (1) addition of an explicit definition of Wolbachia exposure for residents residing in intervention sites based on the duration of Wolbachia exposure at point of testing, (2) incorporation of a high-dimensional set of anthropogenic and environmental characteristics in the analysis plan to adjust for baseline risk factors of dengue transmission, and (3) addition of alternative statistical analyses for endpoints to control for post hoc imbalance in cluster-based environmental and anthropogenic characteristics., Discussion: The findings from this study will provide the first experimental evidence for the efficacy of releasing male-Wolbachia infected mosquitoes to reduce dengue incidence in a cluster-randomised controlled trial. The trial will conclude in 2024 and results will be reported shortly thereafter., Trial Registration: ClinicalTrials.gov, identifier: NCT05505682. Registered on 16 August 2022. Retrospectively registered. Last updated 11 November 2023., (© 2024. The Author(s).)
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- 2024
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34. Virulence Comparison of a Comprehensive Panel of Xylella fastidiosa Pierce's Disease Isolates from California.
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Burbank L, Gomez L, Shantharaj D, Abdelsamad N, Vasquez K, Burhans A, Ortega B, Rodriguez SH, Strickland J, Krugner R, De La Fuente L, and Naegele R
- Subjects
- California, Virulence, Nicotiana microbiology, Xylella genetics, Xylella pathogenicity, Vitis microbiology, Plant Diseases microbiology
- Abstract
Xylella fastidiosa , the causal agent of Pierce's disease of grapevine, has been found in all major grape-growing regions in California, U.S.A. Large collections of X. fastidiosa isolates are available from these areas, which enable comparative studies of pathogen genetic traits and virulence. Owing to the significant resource requirements for experiments with X. fastidiosa in grapevine, however, most studies use only a single isolate to evaluate disease, and it is not clear how much variability between isolates impacts disease development in experimental or natural settings. In this study, a comprehensive panel of X. fastidiosa isolates from all California grape-growing regions was tested for virulence in susceptible grapevine and in the model host plant, tobacco. Seventy-one isolates were tested, 29 in both grapevine and tobacco. The results of this study highlight the inherent variability of inoculation experiments with X. fastidiosa , including variation in disease severity in plants inoculated with a single isolate, and variability between experimental replicates. There were limited differences in virulence between isolates that were consistent across experimental replicates, or across different host plants. This suggests that choice of isolate within the X. fastidiosa subsp. fastidiosa Pierce's disease group may not make any practical difference when testing in susceptible grape varieties, and that pathogen evolution has not significantly changed virulence of Pierce's disease isolates within California. The location of isolation also did not dictate relative disease severity. This information will inform experimental design for future studies of X. fastidiosa in grapevine and provide important context for genomic research., Competing Interests: The author(s) declare no conflict of interest.
- Published
- 2024
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35. A three-phase algorithm for the pollution traveling Salesman problem.
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García-Vasquez K, Linfati R, and Escobar JW
- Abstract
This paper studies a variant of the Pollution Traveling Salesman Problem (PTSP) focused on fuel consumption and pollution emissions (PTSPC). The PTSPC generalizes the well-known Traveling Salesman Problem (TSP), classified as NP-Hard. In the PTSPC, a vehicle must deliver a load to each customer through a Hamiltonian cycle, minimizing an objective function that considers the speed of each edge, the mass of the truck, the mass of the load pending delivery, and the distance traveled. We have proposed a three-phase algorithm for the PTSPC. The first phase solves the Traveling Salesman Problem (TSP) exactly with a time limit and heuristically using a Nearest Neighborhood Search approach. This phase considers the constraints associated with the PTSPC by using commercial software. In the second phase, both the obtained solutions and their inverse sequences from the initial phase undergo enhancement utilizing metaheuristic algorithms tailored for the PTSPC. These algorithms include Variable Neighborhood Search (VNS), Tabu Search (TS), and Simulated Annealing (SA). Subsequently, for the third phase, the best solution identified in the second phase-determined by having the minimum value by the PTSPC objective function-is subjected to resolution by a mathematical model designed for the PTSPC, considering the heuristic emphasis of commercial software. The efficiency of the former algorithm has been validated through experimentation involving the adaptation of instances from the Pollution Routing Problem (PRP) to the PTSPC. This approach demonstrates the capacity to yield high-quality solutions within acceptable computing times., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)
- Published
- 2024
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36. What Laboratories Can Do to Make Space for People with Disabilities.
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Vasquez K
- Published
- 2024
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37. Head Flail Corridors From Sled Impact Acceleration Tests for Use in Occupant-Centric Vehicle Design.
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Olszko A, Abraczinskas A, McGovern S, Robinette A, Vasquez K, Chancey VC, and Brozoski F
- Subjects
- Humans, Accidents, Traffic prevention & control, Biomechanical Phenomena, Acceleration, Head, Craniocerebral Trauma prevention & control
- Abstract
Introduction: In aircraft crashes, injuries to the head and upper torso are frequently reported, with head injury reported most frequently of all body regions. Because preventing flail of the head and body is of utmost importance for occupant survival, the Aircraft Crash Survival Design Guide (ACSDG), the guide to crashworthy aircraft design, published flail envelopes. However, the ACSDG flail envelopes are based on a single test with an anthropomorphic test device subjected to a frontal acceleration. In this article, human research volunteer (HRV) response data are used to calculate head flail corridors and evaluate the ACSDG flail envelopes., Materials and Methods: Data from HRV sled tests were obtained from the historical Naval Biodynamics Laboratory collection of the Biodynamics Data Resource. Digitized high-speed film for each test was tracked and processed to represent the head flail response in a format amenable to corridor development. Time-based and position-based head flail corridors were developed for groups of exposure-matched tests and then compared to the ACSDG flail envelopes., Results: A collection of 714 HRV sled tests conducted in six different impact directions ranging from 3 to 15 g was used to develop time-based and position-based head flail corridors for 39 match groups. The ACSDG vertical limit and anteroposterior limit and curve were not exceeded by the flail corridors, but the lateral limit and curve were exceeded by 4.6 cm to 15.8 cm., Conclusions: The flail corridors provide a useful baseline for representing the well-restrained occupant response at lower, non-injurious exposure levels and across multiple impact directions. Under these conditions, the ACSDG lateral limit and curve are not adequate. At higher exposure levels or with modified restraints, seating, or equipment, the ACSDG vertical limit and anteroposterior limit and curves may also be inadequate., (Published by Oxford University Press on behalf of the Association of Military Surgeons of the United States 2023. This work is written by (a) US Government employee(s) and is in the public domain in the US.)
- Published
- 2023
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38. Food insecurity and levels of marginalization: food accessibility, consumption and concern in Mexico.
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Martínez-Martínez OA, Gil-Vasquez K, and Romero-González MB
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- Humans, Mexico, Data Collection, Food Insecurity, Adaptation, Psychological, Budgets
- Abstract
Background: Food insecurity continues to be a problem throughout the world. When estimating food insecurity, few studies analyze the contexts where the phenomenon takes place. By bearing in mind levels of marginalization in four states of Mexico, this paper answers two questions: (I) What problems are experienced with access to food, and how these difficulties affect the amount of food consumed in households? and (II) How do households experience the concern of running out of food?, Methods: Our qualitative study draws data from urban and semi-urban areas of four Mexican states: Mexico City, Tamaulipas, the State of Mexico, and Oaxaca. Each state presents different levels of well-being. The study's participants are selected using the snowball method. Eligibility criteria are based on demographic characteristics such as education, age, and gender. A thematic analytical approach is conducted to analyze collected data from a total of 212 semi-structured interviews., Results: The study's findings indicate that concern of food scarcity is a generalized feeling among participants across different levels of marginalization. Individuals with stable jobs living in contexts of low levels of marginalization experience worriedness when their budgets tightened before the end of the payday, a bi-weekly payment format, named the quincena in México. This psychological state of mind changes through the payday cycle, a period when the direct relationship between food accessibility and consumption weakens. In response, individuals develop strategies to cope with the uncertainty of experiencing food insecurity, such as rationing food portions and/or hoarding food supplies. Even when food accessibility exists, interviewees identify insufficient income as the primary issue in contexts of low and very low levels of marginalization., Conclusions: Conclusive remarks drawn from our analysis underline the importance of the context of marginalization in influencing households' experiences with food insecurity. At the quincena's end, food insecurity increases, even in contexts of very low marginalization. Our study calls for rethinking the scales employed to measure food insecurity, specifically the questions related to fear of food scarcity. Coping strategies are implemented by surveyed individuals to resolve issues and repercussions that emerge from experiencing food insecurity differ by context of marginalization., (© 2023. BioMed Central Ltd., part of Springer Nature.)
- Published
- 2023
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39. Genetic events associated with venetoclax resistance in CLL identified by whole-exome sequencing of patient samples.
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Khalsa JK, Cha J, Utro F, Naeem A, Murali I, Kuang Y, Vasquez K, Li L, Tyekucheva S, Fernandes SM, Veronese L, Guieze R, Sasi BK, Wang Z, Machado JH, Bai H, Alasfour M, Rhrissorrakrai K, Levovitz C, Danysh BP, Slowik K, Jacobs RA, Davids MS, Paweletz CP, Leshchiner I, Parida L, Getz G, and Brown JR
- Subjects
- Humans, Bridged Bicyclo Compounds, Heterocyclic pharmacology, Drug Resistance, Neoplasm genetics, Exome Sequencing, Myeloid Cell Leukemia Sequence 1 Protein genetics, Proto-Oncogene Proteins c-bcl-2, Antineoplastic Agents pharmacology, Leukemia, Lymphocytic, Chronic, B-Cell drug therapy, Leukemia, Lymphocytic, Chronic, B-Cell genetics, Leukemia, Lymphocytic, Chronic, B-Cell pathology
- Abstract
Although BCL2 mutations are reported as later occurring events leading to venetoclax resistance, many other mechanisms of progression have been reported though remain poorly understood. Here, we analyze longitudinal tumor samples from 11 patients with disease progression while receiving venetoclax to characterize the clonal evolution of resistance. All patients tested showed increased in vitro resistance to venetoclax at the posttreatment time point. We found the previously described acquired BCL2-G101V mutation in only 4 of 11 patients, with 2 patients showing a very low variant allele fraction (0.03%-4.68%). Whole-exome sequencing revealed acquired loss(8p) in 4 of 11 patients, of which 2 patients also had gain (1q21.2-21.3) in the same cells affecting the MCL1 gene. In vitro experiments showed that CLL cells from the 4 patients with loss(8p) were more resistant to venetoclax than cells from those without it, with the cells from 2 patients also carrying gain (1q21.2-21.3) showing increased sensitivity to MCL1 inhibition. Progression samples with gain (1q21.2-21.3) were more susceptible to the combination of MCL1 inhibitor and venetoclax. Differential gene expression analysis comparing bulk RNA sequencing data from pretreatment and progression time points of all patients showed upregulation of proliferation, B-cell receptor (BCR), and NF-κB gene sets including MAPK genes. Cells from progression time points demonstrated upregulation of surface immunoglobulin M and higher pERK levels compared with those from the preprogression time point, suggesting an upregulation of BCR signaling that activates the MAPK pathway. Overall, our data suggest several mechanisms of acquired resistance to venetoclax in CLL that could pave the way for rationally designed combination treatments for patients with venetoclax-resistant CLL., (© 2023 by The American Society of Hematology.)
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- 2023
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40. Children's memory for gender-neutral pronouns.
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Vasquez K, Tompkins R, Olson KR, and Dunham Y
- Subjects
- Male, Female, Humans, Child, Adolescent, Child, Preschool, Mental Recall, Reading, Language, Gender Identity
- Abstract
Are there disparities in children's memory for gender-neutral pronouns compared with gendered pronouns? We explored this question in two preregistered studies with 4- to 10-year-old children (N = 168; 79 boys, 89 girls, 0 gender-diverse). Participants were presented with a memory task. An experimenter read an illustrated story about a target character. Participants were asked to verbally repeat the story to measure spontaneous pronoun use and then to explicitly recall the characters' pronouns. In Study 1 the story characters had typically feminine or typically masculine appearances (determined by independent raters), whereas in Study 2 the characters had gender-neutral appearances. In both studies, targets were referred to with gendered or gender-neutral pronouns. In both studies, children more accurately recalled gendered pronouns than gender-neutral pronouns. However, on most tasks, children only used "they" if a character had gender-neutral pronouns, and almost never used "they" if a character had gendered pronouns. We also found some evidence suggesting that older children more accurately recall gender-neutral pronouns compared with younger children., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
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41. Assessing the efficacy of male Wolbachia-infected mosquito deployments to reduce dengue incidence in Singapore: study protocol for a cluster-randomized controlled trial.
- Author
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Ong J, Ho SH, Soh SXH, Wong Y, Ng Y, Vasquez K, Lai YL, Setoh YX, Chong CS, Lee V, Wong JCC, Tan CH, Sim S, Ng LC, and Lim JT
- Subjects
- Animals, Male, Humans, Mosquito Control methods, Mosquito Vectors, Incidence, Seroepidemiologic Studies, Singapore epidemiology, Randomized Controlled Trials as Topic, Wolbachia, Dengue epidemiology, Dengue prevention & control, Aedes
- Abstract
Background: Dengue is a severe environmental public health challenge in tropical and subtropical regions. In Singapore, decreasing seroprevalence and herd immunity due to successful vector control has paradoxically led to increased transmission potential of the dengue virus. We have previously demonstrated that incompatible insect technique coupled with sterile insect technique (IIT-SIT), which involves the release of X-ray-irradiated male Wolbachia-infected mosquitoes, reduced the Aedes aegypti population by 98% and dengue incidence by 88%. This novel vector control tool is expected to be able to complement current vector control to mitigate the increasing threat of dengue on a larger scale. We propose a multi-site protocol to study the efficacy of IIT-SIT at reducing dengue incidence., Methods/design: The study is designed as a parallel, two-arm, non-blinded cluster-randomized (CR) controlled trial to be conducted in high-rise public housing estates in Singapore, an equatorial city-state. The aim is to determine whether large-scale deployment of male Wolbachia-infected Ae. aegypti mosquitoes can significantly reduce dengue incidence in intervention clusters. We will use the CR design, with the study area comprising 15 clusters with a total area of 10.9 km
2 , covering approximately 722,204 residents in 1713 apartment blocks. Eight clusters will be randomly selected to receive the intervention, while the other seven will serve as non-intervention clusters. Intervention efficacy will be estimated through two primary endpoints: (1) odds ratio of Wolbachia exposure distribution (i.e., probability of living in an intervention cluster) among laboratory-confirmed reported dengue cases compared to test-negative controls and (2) laboratory-confirmed reported dengue counts normalized by population size in intervention versus non-intervention clusters., Discussion: This study will provide evidence from a multi-site, randomized controlled trial for the efficacy of IIT-SIT in reducing dengue incidence. The trial will provide valuable information to estimate intervention efficacy for this novel vector control approach and guide plans for integration into national vector control programs in dengue-endemic settings., Trial Registration: ClinicalTrials.gov, identifier: NCT05505682 . Registered on 16 August 2022. Retrospectively registered., (© 2022. The Author(s).)- Published
- 2022
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42. Influence of public hesitancy and receptivity on reactive behaviours towards releases of male Wolbachia-Aedes mosquitoes for dengue control.
- Author
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Lwin MO, Ong Z, Panchapakesan C, Sheldenkar A, Soh LT, Chen I, Li X, Niah W, Vasquez K, Sim S, and Ng LC
- Subjects
- Animals, Male, Humans, Mosquito Vectors, Wolbachia, Aedes, Dengue prevention & control, Insect Bites and Stings
- Abstract
Singapore, a highly urbanized Asian tropical country that experiences periodic dengue outbreaks, is piloting field releases of male Wolbachia-carrying Aedes aegypti mosquitoes with the aim of suppressing urban populations of the primary dengue vector Aedes aegypti. This study proposes and assesses a model to explain the roles of hesitancy and receptivity towards Project Wolbachia-Singapore in influencing reactive mosquito prevention behaviors (reactive behaviors) towards the release of Wolbachia-Aedes mosquitoes for residents living in the release sites. Interestingly, both hesitancy and receptivity predicted greater instances of reactive behaviors. The model also examines the roles of general knowledge about Wolbachia technology, perceived severity of mosquito bites, perceived density of mosquitoes, and social responsibility as predictors of hesitancy, receptivity, and reactive behaviors towards the release of Wolbachia-Aedes mosquitoes. Hesitancy towards the project mediated the effects of general knowledge, perceived severity of mosquito bites, and perceived density of mosquitoes on reactive behaviors towards the releases, although receptivity towards the project did not. Having less knowledge about Project Wolbachia-Singapore was associated with higher hesitancy towards the project and higher likelihood of performing reactive behaviors towards the releases. Individuals who perceive mosquito bites to be more severe and think that there are more mosquitoes in their living environments were also more likely to be hesitant about the project and practice reactive behaviors. However, both hesitancy and receptivity towards the project mediated the effect of social responsibility on reactive behaviors. Receptivity towards the project was driven by social responsibility, which was also associated with reduced hesitancy towards the project. Our findings suggest that, to address the hesitancy reported by a minority of participants, future outreach efforts should focus on strengthening the public's sense of social responsibility and on tailored education campaigns targeting groups with low levels of knowledge of the project., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2022 Lwin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Published
- 2022
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43. Macrophage TGF-β signaling is critical for wound healing with heterotopic ossification after trauma.
- Author
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Patel NK, Nunez JH, Sorkin M, Marini S, Pagani CA, Strong AL, Hwang CD, Li S, Padmanabhan KR, Kumar R, Bancroft AC, Greenstein JA, Nelson R, Rasheed HA, Livingston N, Vasquez K, Huber AK, and Levi B
- Subjects
- Humans, Chromatin metabolism, Ligands, Macrophages metabolism, Receptor, Transforming Growth Factor-beta Type I genetics, Wound Healing, Transforming Growth Factor beta metabolism, Ossification, Heterotopic metabolism, Transforming Growth Factor beta1 metabolism
- Abstract
Transforming growth factor-β1 (TGF-β1) plays a central role in normal and aberrant wound healing, but the precise mechanism in the local environment remains elusive. Here, using a mouse model of aberrant wound healing resulting in heterotopic ossification (HO) after traumatic injury, we find autocrine TGF-β1 signaling in macrophages, and not mesenchymal stem/progenitor cells, is critical in HO formation. In-depth single-cell transcriptomic and epigenomic analyses in combination with immunostaining of cells from the injury site demonstrated increased TGF-β1 signaling in early infiltrating macrophages, with open chromatin regions in TGF-β1-stimulated genes at binding sites specific for transcription factors of activated TGF-β1 (SMAD2/3). Genetic deletion of TGF-β1 receptor type 1 (Tgfbr1; Alk5), in macrophages, resulted in increased HO, with a trend toward decreased tendinous HO. To bypass the effect seen by altering the receptor, we administered a systemic treatment with TGF-β1/3 ligand trap TGF-βRII-Fc, which resulted in decreased HO formation and a delay in macrophage infiltration to the injury site. Overall, our data support the role of the TGF-β1/ALK5 signaling pathway in HO.
- Published
- 2022
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44. IACUC/EHS collaboration to prevent non-compliance.
- Author
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Rooks K, Maurer L, Calderon A, and Vasquez K
- Subjects
- Animal Welfare, Animals, Licensure, Animal Care Committees
- Published
- 2022
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45. [Risk factors for malnutrition at two years of corrected age in preterm infants under 32 weeks].
- Author
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Vernal Silva P, Mena Nannig P, Diaz Gonzalez A, Henriquez Höfter MT, Pittaluga Pierdiluca E, D'Apremont Ormeño I, Morgues Nudman M, Standen J, and Johannessen Vasquez K
- Subjects
- Infant, Female, Humans, Infant, Newborn, Overweight epidemiology, Retrospective Studies, Birth Weight, Aftercare, Thinness epidemiology, Patient Discharge, Risk Factors, Infant, Premature, Malnutrition
- Abstract
Post-discharge nutrition of preterm newborns must avoid excessive or insufficient weight gain and optimal length and head circumference growth. In Chile, premature infants less than 32 wee ks at birth receive fortified formulas during the first year, unless they are exclusively breastfed., Objective: To describe growth and identify the risk of malnutrition at 24 months., Patients and Method: Retrospective cohort study that analyzes growth from birth to 2 years of corrected age in preterm patients < 32 weeks of gestational age. Z-score of weight, length, head circumference, and Body Mass Index (BMI) were analyzed. Factors related to Z BMI at 24 months were analyzed as follows: Eutrophic: Z BMI between -1 and +1; Overweight: Z BMI > +1; Underweight: Z BMI < -1., Results: 996 preterm infants were included, 559 completed check-ups at 24 months. 64.5% were eutrophic, 18.4% overweight, and 17.1% underweight. Multivariate analysis showed that risk of overweight was associated with birth weight > 1460 g: OR 5.77 (2.11-15.77) and Z BMI > 1.6 at 6 months: OR 2.67 (1.91-3.74); underweight risk was associated with birth weight < 1000g: OR 3.1 (1.1-8.8) and Z BMI < -0.75 at 6 months: OR 8.2 (4.3-16.3)., Conclusions: The greater risk of overweight and underweight can be anticipated in premature infants under 32 weeks with birth weight or Z BMI at 6 months of corrected age.
- Published
- 2022
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46. Implementing DASH-aligned Congregate Meals and Self-Measured Blood Pressure in two senior centers: An open label study.
- Author
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Hashemi A, Vasquez K, Guishard D, Naji M, Ronning A, George-Alexander G, Vasquez D, Sylvester C, Pagano W, Khalida C, Coffran C, Ezeonu T, Fofana K, Bielopolski D, Vaughan R, Qureshi A, Tobin JN, and Kost RG
- Subjects
- Aged, Blood Pressure, Blood Pressure Monitoring, Ambulatory, COVID-19, Female, Humans, Male, Meals, Self Efficacy, Dietary Approaches To Stop Hypertension, Hypertension diagnosis, Hypertension epidemiology, Hypertension prevention & control
- Abstract
Background and Aims: Cardiovascular Disease (CVD) poses significant health risks for seniors, especially among low-income and minority communities. Senior centers offer multiple services. We tested whether implementing two evidence-based interventions- DASH-aligned meals provided through an existing congregate meal program, and support for home Self-Measured Blood Pressure (SMBP) monitoring-lowers blood pressure among participants at two senior centers serving low-income, racially diverse communities., Methods and Results: Open-label study, enrolling clients aged ≥60, eating ≥4 meals/week at two NYC senior centers. Participants received DASH-aligned congregate meals, and training in nutrition, BP management education, and personal SMBP device. Co-Primary outcomes: a) change in systolic BP measured by independent health professionals, and b) change in percent with "controlled BP" (Eighth Joint National Committee (JNC-8) Guidelines), at Month 1 compared to Baseline., Secondary Outcomes: Changes in BP at Months 3 and 5/6 (last measure). We enrolled 94 participants; COVID closures interrupted implementation mid-study. Mean systolic BP at Month-1 changed by -4.41 mmHg (n = 61 p = 0.07) compared to Baseline. Participants with controlled BP increased (15.7%) at Month 1. Change in mean BP at Month 1 was significantly correlated with BMI (p = 0.02), age (p = 0.04), and baseline BP (p < 0.001). Mean systolic SMBP changed by -6.9 mmHg (p = 0.004) at Months 5/6., Conclusions: Implementing an evidence-based multi-component BP-lowering intervention within existing congregate meal programs at senior centers serving minority and low-income communities is feasible, and early findings show promising evidence of effectiveness. This approach to cardiovascular risk reduction should be further tested for widespread adoption and impact. Registered on ClinicalTrials.gov NCT03993808 (June 21st, 2019)., Competing Interests: Declaration of competing interest The authors have no conflicts of interest to declare., (Copyright © 2022 The Authors. Published by Elsevier B.V. All rights reserved.)
- Published
- 2022
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47. Parents' employment, income, and finances before and during the COVID-19 pandemic.
- Author
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Garrison ST, Rampold SD, Vasquez K, Gillen M, and Baker LM
- Abstract
The COVID-19 pandemic brought grave financial concerns for families in the United States as they attempted to navigate the multifaceted impacts of the pandemic. The present descriptive study examined Florida families' employment characteristics, credit card debt, savings characteristics, use of savings based on employment and income variables, and patterns of use of the first 2020 economic impact payment during the early stages of the COVID-19 pandemic. Responses to an online questionnaire were collected from 526 Florida residents, age 18 or older, who were parents of minor children during the time the study was conducted. Findings are indicative of varying financial impacts on families based on gender, marital status, income level, and employment status related to COVID-19. Implications are presented for employers, educators, researchers, policymakers, and families., (© 2022 American Council on Consumer Interests.)
- Published
- 2022
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48. A Household-Based Survey to Understand Factors Influencing Awareness, Attitudes and Knowledge towards Wolbachia-Aedes Technology.
- Author
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Soh LT, Ong Z, Vasquez K, Chen I, Li X, Niah W, Panchapakesan C, Sheldenkar A, Sim S, Ng LC, and Lwin MO
- Subjects
- Animals, Attitude, Male, Mosquito Vectors, Technology, Aedes, Dengue, Wolbachia
- Abstract
In 2016, Singapore introduced the release of male Wolbachia-Aedes mosquitoes to complement vector control efforts and suppress Aedes aegypti mosquitoes in selected study sites. With ongoing expansion of Project Wolbachia- Singapore to cover larger areas, a household-based survey was conducted between July 2019 to February 2020 in two Project Wolbachia study sites using a structured questionnaire, to evaluate current sentiments and assess the need for enhanced public messaging and engagement. The association of factors that influence awareness, attitudes, and knowledge towards the use of Wolbachia-Aedes technology was analysed using Pearson's Chi-square test and binary logistic regression. Of 500 respondents, 74.8% were aware of Project Wolbachia- Singapore. Comparatively, the level of knowledge on Wolbachia-Aedes technology was lower, suggesting knowledge gaps that require enhanced communication and messaging to address misinformation. Longer exposure to the project predicted greater awareness, whereas higher education levels predicted higher knowledge levels. Younger age groups and higher education levels were associated with high acceptance towards the project. High levels of trust and acceptance towards the project were also observed across the population. The public's positive perception of the project is a testament to the effective public communication undertaken to date and will facilitate programme expansion.
- Published
- 2021
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49. Author Correction: Serum immunoglobulin free light chains and their association with clinical phenotypes, serology and activity in patients with IgG4‑related disease.
- Author
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Martín-Nares E, Saavedra-González V, Fagundo-Sierra R, Santinelli-Núñez BE, Romero-Maceda T, Calderón-Vasquez K, and Hernandez-Molina G
- Published
- 2021
- Full Text
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50. Novel Lineage-Tracing System to Identify Site-Specific Ectopic Bone Precursor Cells.
- Author
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Pagani CA, Huber AK, Hwang C, Marini S, Padmanabhan K, Livingston N, Nunez J, Sun Y, Edwards N, Cheng YH, Visser N, Yu P, Patel N, Greenstein JA, Rasheed H, Nelson R, Kessel K, Vasquez K, Strong AL, Hespe GE, Song JY, Wellik DM, and Levi B
- Subjects
- Adipocytes metabolism, Animals, Chondrocytes metabolism, Disease Models, Animal, Ectopic Gene Expression, Epigenomics, Female, Gene Expression Profiling, Homeodomain Proteins genetics, Homeodomain Proteins metabolism, Male, Mice, Mice, Transgenic, Muscle, Skeletal metabolism, Ossification, Heterotopic pathology, Osteoblasts metabolism, Single-Cell Analysis, Tendons metabolism, Bone and Bones metabolism, Cell Differentiation, Cell Lineage, Mesenchymal Stem Cells metabolism, Ossification, Heterotopic genetics, Ossification, Heterotopic metabolism, Osteogenesis
- Abstract
Heterotopic ossification (HO) is a form of pathological cell-fate change of mesenchymal stem/precursor cells (MSCs) that occurs following traumatic injury, limiting range of motion in extremities and causing pain. MSCs have been shown to differentiate to form bone; however, their lineage and aberrant processes after trauma are not well understood. Utilizing a well-established mouse HO model and inducible lineage-tracing mouse (Hoxa11-CreER
T2 ;ROSA26-LSL-TdTomato), we found that Hoxa11-lineage cells represent HO progenitors specifically in the zeugopod. Bioinformatic single-cell transcriptomic and epigenomic analyses showed Hoxa11-lineage cells are regionally restricted mesenchymal cells that, after injury, gain the potential to undergo differentiation toward chondrocytes, osteoblasts, and adipocytes. This study identifies Hoxa11-lineage cells as zeugopod-specific ectopic bone progenitors and elucidates the fate specification and multipotency that mesenchymal cells acquire after injury. Furthermore, this highlights homeobox patterning genes as useful tools to trace region-specific progenitors and enable location-specific gene deletion., (Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.)- Published
- 2021
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