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6 results on '"Vecchiarelli, Pietro"'

2. Prevention and treatment of catheter-related venous thrombosis in long-term parenteral nutrition: A SINuC position statement

Author

Zaccone, Vincenzo, primary, Santoro, Luca, additional, Guerrieri, Emanuele, additional, Diblasi, Ilaria, additional, Roncarati, Ilaria, additional, Viticchi, Giovanna, additional, Vecchiarelli, Pietro, additional, Santoliquido, Angelo, additional, Fiore, Francesca, additional, Molfino, Alessio, additional, Landi, Francesco, additional, Moroncini, Gianluca, additional, Gasbarrini, Antonio, additional, Muscaritoli, Maurizio, additional, and Falsetti, Lorenzo, additional

Published
2023
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3. Polymyxin-B hemoperfusion in septic patients: analysis of a multicenter registry

Author

Cutuli, Salvatore Lucio, Artigas, Antonio, Fumagalli, Roberto, Monti, Gianpaola, Ranieri, Vito Marco, Ronco, Claudio, Antonelli, Massimo, Maviglia, Riccardo, Cicconi, Sandra, Silvestri, Davide, Bello, Giuseppe, Brendolan, Alessandra, Nalesso, Federico, Villa, Gianluca, Piccinni, Pasquale, Martin, Erica, Cantaluppi, Vincenzo, Vesconi, Sergio, Casella, Giampaolo, Fasanella, Egidio, Debitonto, Michele, Monza, Gianmario, Blasetti, Angelo, Coletta, Rosaria, D’Ambrosio, Michele, Cinnella, Gilda, Murino, Patrizia, Piscitelli, Eugenio, Centonze, Gaetano, Cucurachi, Marco, Altieri, Giuseppe, Leonardo, Vincenzo, Idra, Anna Sara, del Rosso, Goffredo, Polidoro, Maria, Stigliano, Nicola, Pittella, Giuseppe, Paternoster, Gianluca, Pulito, Giuseppe, Puscio, Daniela, Cingolani, Diego, Falzetti, Gabriele, Vecchiarelli, Pietro, Giunta, Francesco, Forfori, Francesco, Castiglione, Giacomo, Greco, Stefano, Capra, Carlo, Crema, Luciano, Tamayo, Leonor, Urbano, Cristina, Pezza, Brunello, Zarrillo, Nadia, di Monaco, Pasquale, Climaco, Giuseppe, de Negri, Pasquale, Modano, Pasqualina, Pagliarulo, Riccardo, Petrillo, Claudio, Stripoli, Tania, Oggioni, Roberto, Campiglia, Laura, Valletta, Anna Rita, Lugano, Manuela, Milella, Domenico, Micucci, Laura, Reist, Ursula, Ensner, Rolf, Gianbarba, Christian, Brander, Lukas, Paul, Rajib, Crawla, Rajesh, Jasujia, Sanjeev, Pande, Rajesh, Dileep, Pratibha, Sundar, Sankaran, Ganesan, Raju, Dewan, Sandeep, Nangia, Vivek, Mani, Raj Kumar, Singh, Omender, Sathe, Pracee, Sachin, Gupta, D’Costa, Pradeep M., Srivanas, Samavedam, Singh, Yogendra Pal, Doi, Kent, Taki, Fumika, Roca, Ricard Ferrer, Medina, Eduardo Romay, Gernacho, Josè, Martí, Francisco, Martinez-Ruiz, Alberto, Martinez-Sagasti, Fernando, Crespo, Rafael Zaragoza, Torti, Paola, Terzi, Valeria, and The EUPHAS 2 Collaborative Group

Published
2016
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4. Acute intestinal failure: International multicenter point-of-prevalence study

Author

Reintam Blaser, Annika, primary, Ploegmakers, Ilse, additional, Benoit, Michael, additional, Holst, Mette, additional, Rasmussen, Henrik Hojgaard, additional, Burgos, Rosa, additional, Forbes, Alastair, additional, Shaffer, Jon, additional, Gabe, Simon, additional, Irtun, Oivind, additional, Thibault, Ronan, additional, Klek, Stanislaw, additional, Olde Damink, Steven WM, additional, van de Poll, Marcel, additional, Panisic-Sekeljic, Marina, additional, Wanten, Geert, additional, Pironi, Loris, additional, Mihnovits, Vladislav, additional, Britenkova, Antonina, additional, Lind, Kadri, additional, Pertsev, Ivan, additional, Lansche, Gregor, additional, Sasdelli, Anna Simona, additional, Bodnar, Zsolt, additional, Pracca, Francisco, additional, Bioni, Italo, additional, Kekstas, Gintautas, additional, Venlavicute, Karolina, additional, Vecchiarelli, Pietro, additional, Krznaric, Zeljko, additional, Kunovic, Ana, additional, Nunez, Ramiro Manzano, additional, Ordonez, Carlos A., additional, Lepp, Hanna-Liis, additional, Compher, Charlene, additional, Aloupis, Marianne, additional, Senussi, Nizar, additional, Murillo, Ana Zugasti, additional, Maíz-Jiménez, María, additional, Matia, Pilar, additional, Wanden-Berghe, Carmina, additional, and Dabrowski, Wojciech, additional

Published
2020
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5. Acute intestinal failure: International multicenter point-of-prevalence study

Author

Gregor Lansche, Marcel C. G. van de Poll, Henrik Højgaard Rasmussen, Charlene Compher, Øivind Irtun, Italo Bioni, Pilar Matía, Carlos A. Ordoñez, Steven W.M. Olde Damink, Alastair Forbes, Anna Simona Sasdelli, Zsolt Bodnár, Gintautas Kekstas, María Maíz-Jiménez, Ana Zugasti Murillo, Nizar H. Senussi, Ronan Thibault, Ramiro Manzano Nunez, Pietro Vecchiarelli, Wojciech Dabrowski, Carmina Wanden-Berghe, Hanna-Liis Lepp, Marianne S. Aloupis, Karolina Venlavicute, Stanislaw Klek, Geert J. A. Wanten, Vladislav Mihnovitš, Michael Benoit, Rosa Burgos, Loris Pironi, Kadri Lind, Ana Kunović, Zeljko Krznaric, Jon Shaffer, Ivan Pertsev, Simon M. Gabe, Francisco Pracca, Antonina Britenkova, Mette Holst, Marina Panisic-Sekeljic, Ilse Ploegmakers, Annika Reintam Blaser, Reintam Blaser, Annika, Ploegmakers, Ilse, Benoit, Michael, Holst, Mette, Rasmussen, Henrik Hojgaard, Burgos, Rosa, Forbes, Alastair, Shaffer, Jon, Gabe, Simon, Irtun, Oivind, Thibault, Ronan, Klek, Stanislaw, Olde Damink, Steven WM, van de Poll, Marcel, Panisic-Sekeljic, Marina, Wanten, Geert, Pironi, Lori, Mihnovits, Vladislav, Britenkova, Antonina, Lind, Kadri, Pertsev, Ivan, Lansche, Gregor, Sasdelli, Anna Simona, Bodnar, Zsolt, Pracca, Francisco, Bioni, Italo, Kekstas, Gintauta, Venlavicute, Karolina, Vecchiarelli, Pietro, Krznaric, Zeljko, Kunovic, Ana, Nunez, Ramiro Manzano, Ordonez, Carlos A., Lepp, Hanna-Lii, Compher, Charlene, Aloupis, Marianne, Senussi, Nizar, Murillo, Ana Zugasti, Maíz-Jiménez, María, Matia, Pilar, Wanden-Berghe, Carmina, Dabrowski, Wojciech, University of Tartu, Maastricht University Medical Centre (MUMC), Maastricht University [Maastricht], Aalborg University [Denmark] (AAU), Vall d'Hebron University Hospital [Barcelona], Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), University of Bologna/Università di Bologna, Travel expenses and accommodation for AIF SIG meetings were funded by European Society for Clinical Nutrition and Metabolism (ESPEN), Luxembourg for all AIF-SIG members., Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), University of Bologna, MUMC+: MA Heelkunde (9), Surgery, and RS: NUTRIM - R2 - Liver and digestive health

Subjects
Male, 0301 basic medicine, Time Factors, Epidemiology, AIF study group, Critical Care and Intensive Care Medicine, law.invention, 0302 clinical medicine, law, Intestinal failure, Acute care, Prevalence, Nutrition and Dietetic, Hospital Mortality, Aged, 80 and over, Nutrition and Dietetics, acute, Middle Aged, Intensive care unit, 3. Good health, nutrition, Acute Disease, Female, Adult, medicine.medical_specialty, Ileus, Abdominal surgery, 030209 endocrinology & metabolism, parenteral nutrition, Acute, CLASSIFICATION, Sepsis, Young Adult, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, medicine, Humans, Mortality, Aged, 030109 nutrition & dietetics, Nutrition & Dietetics, business.industry, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Parenteral nutrition, medicine.disease, mortality, Intestinal Diseases, lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4], Emergency medicine, 1111 Nutrition and Dietetics, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business
Abstract

Background & aims: Intestinal failure (IF) is defined from a requirement or intravenous supplementation due to failing capacity to absorb nutrients and fluids. Acute IF is an acute, potentially reversible form of IF. We aimed to identify the prevalence, underlying causes and outcomes of acute IF.Methods: This point-of-prevalence study included all adult patients hospitalized in acute care hospitals and receiving parenteral nutrition (PN) on a study day. The reason for PN and the mechanism of IF (if present) were documented by local investigators and reviewed by an expert panel.Results: Twenty-three hospitals (19 university, 4 regional) with a total capacity of 16,356 acute care beds and 1237 intensive care unit (ICU) beds participated in this study. On the study day, 338 patients received PN (21 patients/1000 acute care beds) and 206 (13/1000) were categorized as acute IF. The categorization of reason for PN was revised in 64 cases (18.9% of total) in consensus between the expert panel and investigators. Hospital mortality of all study patients was 21.5%; the median hospital stay was 36 days. Patients with acute IF had a hospital mortality of 20.5% and median hospital stay of 38 days (P > 0.05 for both outcomes). Disordered gut motility (e.g. ileus) was the most common mechanism of acute IF, and 71.5% of patients with acute IF had undergone abdominal surgery. Duration of PN of >= 42 days was identified as being the best cut-off predicting hospital mortality within 90 days. PN >= 42 days, age, sepsis and ICU admission were independently associated with 90-day hospital mortality.Conclusions: Around 2% of adult patients in acute care hospitals received PN, 60% of them due to acute IF. High 90-day hospital mortality and long hospital stay were observed in patients receiving PN, whereas presence of acute IF did not additionally influence these outcomes. Duration of PN was associated with increased 90-day hospital mortality. (C) 2019 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

Published
2020

6. Immunonutrients in critically ill patients: an analysis of the most recent literature.

Author

Annetta MG, Pittiruti M, Vecchiarelli P, Silvestri D, Caricato A, and Antonelli M

Subjects
Animals, Humans, Immunity drug effects, Inflammation drug therapy, Critical Care methods, Critical Illness, Dietary Supplements
Abstract

Modulation of inflammatory and immune response to critical illness has been the goal of much research in the last decade and a variety of drugs and nutrients (so called "immunonutrients") have been tested in experimental models with promising results. Though, in the clinical setting of intensive care, their efficacy have been inconsistently proven, most likely because the effects of each drug may vary in relation to the timing, the dose, the route of administration, the interaction with other nutrients, the severity of illness and many other factors. Though the early studies of the beginning of this century (2000-2009) have shown some clinical benefits, recent multicenter trials (2011-2015) have failed to prove a consistent benefit of immunonutrition in terms of mortality or other clinical endpoints. Reviewing the latest evidence-based documents on this subject (multicenter trials, systematic reviews, meta-analyses and international guidelines), there is no convincing evidence that immunonutrients may be beneficial in the critically ill. Considering that these substances invariably increase the costs of health care and may be unsafe or even harmful in some subgroups, particularly in septic patients, we conclude that routine administration of immune-nutrients (glutamine, arginine, omega-3 fatty acids, selenium, etc.) cannot be currently recommended in the critically ill.

Published
2016

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