43,129 results on '"Velazquez"'
Search Results
2. Effect of Azadirachta indica and Phyllanthus niruri plant meal on performance and health in growing calves
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Pulido-Huertas, S., Mendoza-Martinez, G.D., Espinosa-Ayala, E., Hernandez-Garcia, P.A., Martinez-Gomez, D., Gonzalez-Sanchez, J.F., Martinez-Cortes, I., Velazquez-Cruz, L.A., and Diaz-Galvan, C.
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- 2024
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3. Method of Developing a Culturally Tailored Diabetes Intervention for American Indians
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Scarton, Lisa, Cobas, Heather, Velazquez, Ilse, McClaren, Mariah, Legaspi, Anatolia, Iyer, Samvit, Choate, Annette, Cannady, Tamela K., and Wilkie, Diana J.
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- 2023
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- View/download PDF
4. When a Woman Looks at a Woman: Poetics of the Look in Zhai Yongming's Ekphrastic Writings
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Velazquez-Velazquez, Laura
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- 2022
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5. Desperados: Crypto-Mexicans and Firefly's Mutation of the Western
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Curry, Agnes B. and Velazquez, Josef
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post-western ,western genre ,mexicans in westerns ,state of nature ,theological grace ,utopianism ,domestication ,jayne cobb ,inara sera ,Motion pictures ,PN1993-1999 - Published
- 2022
6. Healthy Parks Healthy People as an Upstream Stress Reduction Strategy
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Yoshino, Aiko, Wilson, Jackson, Velazquez, Edgar J., and Johnson, Eric
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- 2022
7. Detecting Neurodegenerative Diseases using Frame-Level Handwriting Embeddings
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Laouedj, Sarah, Wang, Yuzhe, Villalba, Jesus, Thebaud, Thomas, Moro-Velazquez, Laureano, and Dehak, Najim
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Computer Science - Machine Learning ,Computer Science - Computer Vision and Pattern Recognition - Abstract
In this study, we explored the use of spectrograms to represent handwriting signals for assessing neurodegenerative diseases, including 42 healthy controls (CTL), 35 subjects with Parkinson's Disease (PD), 21 with Alzheimer's Disease (AD), and 15 with Parkinson's Disease Mimics (PDM). We applied CNN and CNN-BLSTM models for binary classification using both multi-channel fixed-size and frame-based spectrograms. Our results showed that handwriting tasks and spectrogram channel combinations significantly impacted classification performance. The highest F1-score (89.8%) was achieved for AD vs. CTL, while PD vs. CTL reached 74.5%, and PD vs. PDM scored 77.97%. CNN consistently outperformed CNN-BLSTM. Different sliding window lengths were tested for constructing frame-based spectrograms. A 1-second window worked best for AD, longer windows improved PD classification, and window length had little effect on PD vs. PDM.
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- 2025
8. The detailed balance property and chemical systems out of equilibrium
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Franco, E. and Velázquez, J. J. L.
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Mathematics - Classical Analysis and ODEs ,Mathematical Physics ,34A, 92B - Abstract
The detailed balance property is a fundamental property that must be satisfied in all the macroscopic systems with a well defined temperature at each point. On the other hand, many biochemical networks work in non-equilibrium conditions and they can be effectively modelled using sets of equations in which the detailed balance condition fails. In this paper we study a class of "out of equilibrium" chemical networks that can be obtained freezing the concentration of some substances in chemical networks for which the detailed balance property holds. In particular, we prove that any chemical system with bidirectional chemical reactions can be extended to a system having additional substances and for which the detailed balance property holds.
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- 2025
9. A search for the anomalous events detected by ANITA using the Pierre Auger Observatory
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The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caracas, I. A., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., de Errico, B. P. de Souza, De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fernandes, A., Fick, B., Figueira, J. M., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Fujii, T., Fuster, A., Galea, C., Galelli, C., García, B., Gaudu, C., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Johnsen, J. A., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lu, L., Luce, Q., Lundquist, J. P., Payeras, A. Machado, Majercakova, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mastrodicasa, M., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Morello, C., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pereira, L. A. S., Martins, E. E. Pereira, Armand, J. Perez, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., de Carvalho, W. Rodrigues, Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Silli, G., Sima, O., Simkova, K., Simon, F., Smau, R., Šmída, R., Sommers, P., Soriano, J. F., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Trimarelli, C., Tueros, M., Unger, M., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vásquez-Ramírez, A., Veberič, D., Ventura, C., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Prechelt, R., Romero-Wolf, A., Wissel, S., and Zeolla, A.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
A dedicated search for upward-going air showers at zenith angles exceeding $110^\circ$ and energies $E>0.1$ EeV has been performed using the Fluorescence Detector of the Pierre Auger Observatory. The search is motivated by two "anomalous" radio pulses observed by the ANITA flights I and III which appear inconsistent with the Standard Model of particle physics. Using simulations of both regular cosmic ray showers and upward-going events, a selection procedure has been defined to separate potential upward-going candidate events and the corresponding exposure has been calculated in the energy range [0.1-33] EeV. One event has been found in the search period between 1 Jan 2004 and 31 Dec 2018, consistent with an expected background of $0.27 \pm 0.12$ events from mis-reconstructed cosmic ray showers. This translates to an upper bound on the integral flux of $(7.2 \pm 0.2) \times 10^{-21}$ cm$^{-2}$ sr$^{-1}$ y$^{-1}$ and $(3.6 \pm 0.2) \times 10^{-20}$ cm$^{-2}$ sr$^{-1}$ y$^{-1}$ for an $E^{-1}$ and $E^{-2}$ spectrum, respectively. An upward-going flux of showers normalized to the ANITA observations is shown to predict over 34 events for an $E^{-3}$ spectrum and over 8.1 events for a conservative $E^{-5}$ spectrum, in strong disagreement with the interpretation of the anomalous events as upward-going showers., Comment: 10+5 Pages of Manuscript plus Supplemental Material, 3+8 figures, Accepted for publication in Physical Review Letters
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- 2025
10. Search for a diffuse flux of photons with energies above tens of PeV at the Pierre Auger Observatory
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The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Ambrosone, A., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Bellido, J. A., Berat, C., Bertaina, M. E., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caraça-Valente, J., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Boone, E. -T., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Freitas, M., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Ghia, P. L., Giaccari, U., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Köhler, J., Krieger, F., Kubatova, M., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lundquist, J. P., Payeras, A. Machado, Mallamaci, M., Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mogarkar, M., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novikov, A., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Ochoa, J., Oliveira, C., Östman, L., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Pytel, K., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodriguez, E., Fernandez, G. Rodriguez, Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Sampathkumar, P., Martin, N. San, Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Vaiman, I., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verpoest, S., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Vuta, J. B., Watanabe, C., Watson, A. A., Weindl, A., Weitz, M., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zas, E., Zavrtanik, D., and Zavrtanik, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Diffuse photons of energy above 0.1 PeV, produced through the interactions between cosmic rays and either interstellar matter or background radiation fields, are powerful tracers of the distribution of cosmic rays in the Galaxy. Furthermore, the measurement of a diffuse photon flux would be an important probe to test models of super-heavy dark matter decaying into gamma-rays. In this work, we search for a diffuse photon flux in the energy range between 50 PeV and 200 PeV using data from the Pierre Auger Observatory. For the first time, we combine the air-shower measurements from a 2 km$^2$ surface array consisting of 19 water-Cherenkov surface detectors, spaced at 433 m, with the muon measurements from an array of buried scintillators placed in the same area. Using 15 months of data, collected while the array was still under construction, we derive upper limits to the integral photon flux ranging from 13.3 to 13.8 km$^{-2}$ sr$^{-1}$ yr$^{-1}$ above tens of PeV. We extend the Pierre Auger Observatory photon search program towards lower energies, covering more than three decades of cosmic-ray energy. This work lays the foundation for future diffuse photon searches: with the data from the next 10 years of operation of the Observatory, this limit is expected to improve by a factor of $\sim$20., Comment: Submitted to JCAP
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- 2025
11. The hyperspace {\omega}(f) when f is a transitive dendrite mapping
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Martínez-Montejano, Jorge M., Méndez, Héctor, and Velázquez-Inzunza, Yajaida N.
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Mathematics - General Topology ,Mathematics - Dynamical Systems - Abstract
Let $X$ be a compact metric space. By $2^X$ we denote the hyperspace of all closed and non-empty subsets of $X$ endowed with the Hausdorff metric. Let $f:X\to X$ be a continuous function. In this paper we study some topological properties of the hyperspace $\omega(f)$, the collection of all omega limits sets $\omega(x,f)$ with $x\in X$. We prove the following: $i)$ If $X$ has no isolated points, then, for every continuous function $f:X\to X$, $int_{2^X}(\omega(f))=\emptyset$. $ii)$ If $X$ is a dendrite for which every arc contains a free arc and $f:X\to X$ is transitive, then the hyperspace $\omega(f)$ is totally disconnected. $iii)$ Let $D_\infty$ be the Wazewski's universal dendrite. Then there exists a transitive continuous function $f:D_\infty\to D_\infty$ for which the hyperspace $\omega(f)$ contains an arc; hence, $\omega(f)$ is not totally disconnected.
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- 2025
12. Cross-Modality Embedding of Force and Language for Natural Human-Robot Communication
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Tejwani, Ravi, Velazquez, Karl, Payne, John, Bonato, Paolo, and Asada, Harry
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Computer Science - Robotics ,Computer Science - Artificial Intelligence ,Computer Science - Human-Computer Interaction - Abstract
A method for cross-modality embedding of force profile and words is presented for synergistic coordination of verbal and haptic communication. When two people carry a large, heavy object together, they coordinate through verbal communication about the intended movements and physical forces applied to the object. This natural integration of verbal and physical cues enables effective coordination. Similarly, human-robot interaction could achieve this level of coordination by integrating verbal and haptic communication modalities. This paper presents a framework for embedding words and force profiles in a unified manner, so that the two communication modalities can be integrated and coordinated in a way that is effective and synergistic. Here, it will be shown that, although language and physical force profiles are deemed completely different, the two can be embedded in a unified latent space and proximity between the two can be quantified. In this latent space, a force profile and words can a) supplement each other, b) integrate the individual effects, and c) substitute in an exchangeable manner. First, the need for cross-modality embedding is addressed, and the basic architecture and key building block technologies are presented. Methods for data collection and implementation challenges will be addressed, followed by experimental results and discussions., Comment: Under review in RSS 2025
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- 2025
13. Study of long-term spectral evolution and X-ray and Gamma-ray correlation of blazars seen by HAWC
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Alfaro, R., Alvarez, C., Andrés, A., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Belmont-Moreno, E., Bernal, A., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Carreón, F., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., Depaoli, D., Di Lalla, N., Hernandez, R. Diaz, Dingus, B. L., DuVernois, M. A., Durocher, M., Díaz-Vélez, J. C., Engel, K., Espinoza, C., Fan, K. L., Fraija, N., Fraija, S., García-González, J. A., Garfias, F., Muñoz, A. Gonzalez, González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Hernández-Cadena, S., Herzog, I., Huang, D., Hueyotl-Zahuantitla, F., Iriarte, A., Joshi, V., Kaufmann, S., Kieda, D., Lara, A., Lee, W. H., Lee, J., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Malone, K., Martinez, O., Martinez-Castellanos, I., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Montes, J. A., Moreno, E., Mostafá, M., Nayerhoda, A., Nellen, L., Nisa, M. U., Noriega-Papaqui, R., Omodei, N., Osorio, M., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E., Salazar, H., Salazar-Gallegos, D., Sandoval, A., Schneider, M., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Varela, E., Villaseñor, L., Wang, X., Watson, I. J., Whitaker, K., Willox, E., Yun-Cárcamo, S., Zhou, H., de León, C., Falcone, Abraham D., and Hancock, Fredric
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
The HAWC Observatory collected 6 years of extensive data, providing an ideal platform for long-term monitoring of blazars in the Very High Energy (VHE) band, without bias towards specific flux states. HAWC continuously monitors blazar activity at TeV energies, focusing on sources with a redshift of {z \lt 0.3}, based on the Third Fermi-LAT Catalog of High-Energy sources. We specifically focused our analysis on Mrk 421 and Mrk 501, as they are the brightest blazars observed by the HAWC Observatory. With a dataset of 2143 days, this work significantly extends the monitoring previously published, which was based on 511 days of observation. By utilizing HAWC data for the VHE {\gamma}-ray emission in the 300 GeV to 100 TeV energy range, in conjunction with Swift-XRT data for the 0.3 to 10 keV X-ray emission, we aim to explore potential correlations between these two bands. For Mrk 501, we found evidence of a long-term correlation. Additionally, we identified a period in the light curve where the flux was very low for more than two years. On the other hand, our analysis of Mrk 421 measured a strong linear correlation for quasi-simultaneous observations collected by HAWC and Swift-XRT. This result is consistent with a linear dependence and a multiple-zone synchrotron self-Compton model to explain the X-ray and the {\gamma}-ray emission. Finally, as suggested by previous findings, we confirm a harder-when-brighter behavior in the spectral evolution of the flux properties for Mrk 421. These findings contribute to the understanding of blazar emissions and their underlying mechanisms.
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- 2025
14. Homoenergetic solutions for the Rayleigh-Boltzmann equation: existence of a stationary non-equilibrium solution
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Miele, Nicola, Nota, Alessia, and Velázquez, Juan J. L.
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Mathematics - Analysis of PDEs ,Mathematical Physics - Abstract
In this paper we consider a particular class of solutions of the linear Boltzmann-Rayleigh equation, known in the nonlinear setting as Homoenergetic solutions. These solutions describe the dynamics of Boltzmann gases under the effect of different mechanical deformations. Therefore, the long-time behaviour of these solutions cannot be described by Maxwellian distributions and it strongly depends on the homogeneity of the collision kernel of the equation. Here we focus on the paradigmatic case of simple shear deformations and in the case of cut-off collision kernels with homogeneity $\gamma\geq 0$, in particular covering the case of Maxwell molecules (i.e. $\gamma=0$) and hard potentials with $0\leq \gamma <1$. We first prove a well-posedness result for this class of solutions in the space of non-negative Radon measures and then we rigorously prove the existence of a stationary solution under the non-equilibrium condition which is induced by the presence of the shear deformation. In the case of Maxwell molecules we prove that there is a different behaviour of the solutions for small and large values of the shear parameter., Comment: 35 pages
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- 2025
15. Study of the IC 443 region with the HAWC observatory
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Alfaro, R., Alvarez, C., Araya, M., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Bernal, A., Caballero-Mora, K. S., Capistran, T., Carramiñana, A., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., Depaoli, D., Desiati, P., Di Lalla, N., Hernandez, R. Diaz, Dingus, B. L., DuVernois, M. A., Díaz-Vélez, J. C., Ergin, T., Espinoza, C., Fang, K., Fraija, N., Fraija, S., García-González, J. A., Goksu, H., González-Cervera, J. A., González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Hernández-Cadena, S., Herzog, I., Hinton, J., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Kaufmann, S., Lara, A., Lee, J., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Malone, K., Martinez, O., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Montes, J. A., Morales-Soto, J. A., Moreno, E., Mostafá, M., Najafi, M., Nellen, L., Nisa, M. U., Noriega-Papaqui, R., Olivera-Nieto, L., Omodei, N., Osorio, M., Ponce, E., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Roth, M., Ruiz-Velasco, E., Salazar, H., Sandoval, A., Schneider, M., Schwefer, G., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Wang, X., Wang, Z., Watson, I. J., Wu, H., Yu, S., Yun-Cárcamo, S., Zhou, H., and de León, C.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Context. Supernova remnants are one potential source class considered a PeVatron (i.e. capable of accelerating cosmic rays above PeV energies). The shock fronts produced after the explosion of the supernova are ideal regions for particle acceleration. IC 443 is a supernova remnant that has been studied extensively at different wavelengths. We study this region using very-high-energy gamma-ray data. Aims. We explore the region of IC 443 using 2966 days of gamma-ray data from the HAWC observatory. We study the emission of this supernova remnant and search for signatures that would show acceleration of (hadronic) cosmic rays at the PeV range. Methods. We use the maximum likelihood estimation and a likelihood ratio test to perform a multi-source fitting search. We find the best-fit morphology and spectrum of the IC 443 region above $\sim$300 GeV that best describes the HAWC data. Results. We observe a point source located at ($\alpha$=94.42$^{\circ}$, $\delta$=22.35$^{\circ}$) that we associate with IC 443. The measured spectrum is a simple power law with an index of -3.14$\pm$0.18, which is consistent with previous TeV observations. We also find a new extended component in the region whose emission is described by a simple power law with an index of -2.49$\pm$0.08 and which we call HAWC J0615+2213. Conclusions. Although we cannot confirm that IC 443 is a hadronic PeVatron, we do not find any sign that the spectrum has a cut off at tens of TeV energies, with the spectrum extending to $\sim$30 TeV. Furthermore, we find a new extended source in the region. While we show evidence that this new source might be a new TeV halo, we defer a detailed analysis of this new source to another publication.
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- 2025
16. EarthView: A Large Scale Remote Sensing Dataset for Self-Supervision
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Velazquez, Diego, López, Pau Rodriguez, Alonso, Sergio, Gonfaus, Josep M., Gonzalez, Jordi, Richarte, Gerardo, Marin, Javier, Bengio, Yoshua, and Lacoste, Alexandre
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Computer Science - Computer Vision and Pattern Recognition - Abstract
This paper presents EarthView, a comprehensive dataset specifically designed for self-supervision on remote sensing data, intended to enhance deep learning applications on Earth monitoring tasks. The dataset spans 15 tera pixels of global remote-sensing data, combining imagery from a diverse range of sources, including NEON, Sentinel, and a novel release of 1m spatial resolution data from Satellogic. Our dataset provides a wide spectrum of image data with varying resolutions, harnessed from different sensors and organized coherently into an accessible HuggingFace dataset in parquet format. This data spans five years, from 2017 to 2022. Accompanying the dataset, we introduce EarthMAE, a tailored Masked Autoencoder, developed to tackle the distinct challenges of remote sensing data. Trained in a self-supervised fashion, EarthMAE effectively processes different data modalities such as hyperspectral, multispectral, topographical data, segmentation maps, and temporal structure. This model helps us show that pre-training on Satellogic data improves performance on downstream tasks. While there is still a gap to fill in MAE for heterogeneous data, we regard this innovative combination of an expansive, diverse dataset and a versatile model adapted for self-supervised learning as a stride forward in deep learning for Earth monitoring., Comment: 2nd Workshop on Computer Vision for Earth Observation (CV4EO) Applications
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- 2025
17. Solar irradiance statistical analysis in Mexico City from 2018 to 2021
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Fernández, C. H. Zepeda, Ramírez-Cerón, M., Cancino-Rojas, X., Barbosa, E. Moreno, Arredondo-Velázquez, M., and Hernández-López, J. M.
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Physics - Space Physics - Abstract
Solar radiation is made up of three components of electromagnetic waves: infrared, visible and ultraviolet. The infrared component is the cause of thermal energy, the visible spectrum allows to see through the eyes and the ultraviolet component is the most energetic and damaging. Solar radiation has several benefits, such as helping to synthesize vitamin D in the skin, favors blood circulation, among others benefits for the human body. In the Earth, it is the main source of energy for agriculture, also used as an alternative source of energy to hydrocarbons, through solar cells. The solar irradiance represents the surface power density with units W/m$^2$ in SI. Too much exposure can cause damage and an increase in value over the time can be can be also damaging. In this work it was used an open data base provided by Secretar\'ia del Medio Ambiente, from which a statistical analysis was performed of the solar irradiance values measured at various meteorological stations in Mexico City and the so-called metropolitan area, from 2018 to 2021. This analysis was carried out per years, months and days. From the solar irradiance values distributions, it was obtained the averages, maximums and means were it was found there was no variation in the solar irradiance values over this period of years.
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- 2025
18. Utilidad de la resonancia magnética avanzada para la aproximación diagnóstica preoperatoria en gliomas
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Garavaglia F, Pueyrredon F, Velazquez D, Rinaudo F, Herrera E, and Campana J
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Gliomas ,Neuroimágenes ,Resonancia Magnética ,Sistema Nervioso Central ,Ki 67 ,Science ,Biology (General) ,QH301-705.5 - Abstract
INTRODUCCIÓN: Los tumores cerebrales son lesiones de gran diversidad histológica y genética, de ellos los gliomas son el grupo más frecuente. Los avances imagenológicos enfocados en la resonancia magnética avanzada y funcional, así como la categorización genética han permitido mejorar el enfoque terapéutico de estos pacientes, pero sin cambios significativos en el pronóstico. OBJETIVO: Reconocer la capacidad de la Espectroscopía, Perfusión y Difusión para el diagnóstico preoperatorio sobre las características histopatológicas e inmunohistoquímicas de las lesiones ocupantes de espacio de origen glial. MATERIAL Y MÉTODO: Se aplicaron técnicas de resonancia magnética avanzada (Espectroscopia - Perfusión - Difusión) a los pacientes con lesiones ocupantes de espacio en SNC con diagnóstico histopatológico de gliomas. Se correlacionaron estos resultados con el análisis histopatológico e inmunohistoquímico de las piezas quirúrgicas. Se revisó la asociación de estos índices imagenológicos (Índice Cho/Cr-Cho/NAA-NAA/Cr-DWI-rCVB) con la histología y la inmunohistoquímica en relación al índice de replicación celular de estas lesiones (anticuerpo KI 67) RESULTADOS: Se evidenció una relación entre aumento de índices de espectroscopia (Cho/Cr y Cho/NAA) e índices de difusión (DWI) y su relación con KI67/MIB1 en tumores de alto grado. DISCUSIÓN: Si bien los resultados no pueden probarse de forma estadística debido al tamaño de la muestra se puede evidenciar asociación entre hallazgos imagenológicos preoperatorios con características genéticas tumorales de forma preoperatoria. CONCLUSION: Las técnicas imagenológicas han avanzado en forma significativa en las últimas décadas, pero poco se ha logrado influir en el pronóstico de pacientes con lesiones gliales del SNC. La posibilidad de conocer en una etapa preoperatoria de las características histológicas e inmunohistoquímicas de los tumores primarios del SNC podría ser de gran ayuda en el abordaje interdisciplinario de estas lesiones.
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- 2023
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19. Pharmacodynamic Studies of Fluorescent Diamond Carriers of Doxorubicin in Liver Cancer Cells and Colorectal Cancer Organoids
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Firestein R, Marcinkiewicz C, Nie L, Chua HK, Velazquez Quesada I, Torelli M, Sternberg M, Gligorijevic B, Shenderova O, Schirhagl R, and Feuerstein GZ
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liver cancer cell-lines ,human colorectal cancer organoids ,fluorescent diamond particles-nv-700/800nm ,doxorubicin ,apoptosis ,Medical technology ,R855-855.5 ,Chemical technology ,TP1-1185 - Abstract
Ron Firestein,1,2,* Cezary Marcinkiewicz,3,4,* Linyan Nie,5 Hui Kheng Chua,1,2 Ines Velazquez Quesada,4 Marco Torelli,6 Mark Sternberg,3 Bojana Gligorijevic,4 Olga Shenderova,6 Romana Schirhagl,5 Giora Z Feuerstein3 1Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, Victoria, 3168, Australia; 2Department of Molecular and Translational Sciences, Monash University, Clayton, Victoria, 3800, Australia; 3Debina Diagnostics Inc., Newtown Square, PA, USA; 4College of Engineering, Department of Bioengineering, Temple University, Philadelphia, PA, USA; 5Groningen University, Groningen, 9727, the Netherlands; 6Adámas Nanotechnologies, Inc., Raleigh, NC, 27617, USA*These authors contributed equally to this workCorrespondence: Giora Z FeuersteinDebina Diagnostics Inc., 33 Bishop Hollow Road, Newtown Square, PA, 19073, USATel +4842221575Email giorafeuerstein@gmail.comBackground: We recently reported on preferential deposition of bare fluorescent diamond particles FDP-NV-700/800nm (FDP-NV) in the liver following intravenous administration to rats. The pharmacokinetics of FDP-NV in that species indicated short residency in the circulation by rapid clearance by the liver. Retention of FDP-NV in the liver was not associated with any pathology. These observations suggested that cancer therapeutics, such as doxorubicin, linked to FDP-NV, could potentially serve for anti-cancer treatment while sparing toxicities of peripheral organs.Purpose: To generate proof-of-concept (POC) and detail mechanisms of action of doxorubicin-coated FDP-NV-700/800nm (FDP-DOX) as a prospective chemotherapeutic for metastatic liver cancer.Methods: FDP-DOX was generated by adsorption chemistry. Experimental design included concentration and time-dependent efficacy studies as compared with naïve (baren) FDP-NV in in vitro liver cancer cells models. Uptake of FDP-NV and FDP-DOX by HepG-2, Hep-3B and hCRC organoids were demonstrated by flow-cytometry and fluorescent microscopy. FDP-DOX pharmacodynamic effects included metabolic as well as cell death biomarkers Annexin V, TUNEL and LDH leakage. DOX desorpted from FDP-DOX was assessed by confocal microscopy and chemical assay of cells fractions.Results: FDP-DOX efficacy was dose- and time-dependent and manifested in both liver cancer cell lines and human CRC organoids. FDP-DOX was rapidly internalized into cancer cells/organoids leading to cancer growth inhibition and apoptosis. FDP-DOX disrupted cell membrane integrity as evident by LDH release and suppressing mitochondrial metabolic pathways (AlamarBlue assay). Access of free DOX to the nuclei was confirmed by direct UV-Visible fluorescent assay and confocal microscopy of DOX fluorescence.Conclusion: The rapid uptake and profound cancer inhibition observed using FDP-DOX in clinically relevant cancer models, highlight FDP-DOX promise for cancer chemotherapeutics. We also conclude that the in vitro data justify further investment in in vivo POC studies.Keywords: liver cancer cell-lines, human colorectal cancer organoids, fluorescent diamond particles-NV-700/800nm, doxorubicin, apoptosis
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- 2021
20. Lung Inflammatory Response to Environmental Dust Exposure in Mice Suggests a Link to Regional Respiratory Disease Risk
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Burr AC, Velazquez JV, Ulu A, Kamath R, Kim SY, Bilg AK, Najera A, Sultan I, Botthoff JK, Aronson E, Nair MG, and Nordgren TM
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salton sea ,dust exposure ,lung inflammation ,asthma ,proteases ,protease activated receptors ,Pathology ,RB1-214 ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Abigail C Burr,1,* Jalene V Velazquez,1,* Arzu Ulu,1 Rohan Kamath,1 Sang Yong Kim,1 Amanpreet K Bilg,1 Aileen Najera,1 Iman Sultan,1 Jon K Botthoff,2 Emma Aronson,3 Meera G Nair,1 Tara M Nordgren1 1Division of Biomedical Sciences, University of California Riverside, Riverside, CA, 92521, USA; 2Center for Conservation Biology, University of California Riverside, Riverside, CA, 92521, USA; 3Department of Plant Pathology and Microbiology, University of California Riverside, Riverside, CA, 92521, USA*These authors contributed equally to this workCorrespondence: Tara M NordgrenDivision of Biomedical Sciences, University of California Riverside, 92521 University Avenue, Riverside, CA, 92521, USATel +1 951 827 3148Email tmnordgren@gmail.comPurpose: The Salton Sea, California’s largest lake, is designated as an agricultural drainage reservoir. In recent years, the lake has experienced shrinkage due to reduced water sources, increasing levels of aerosolized dusts in surrounding regions. Communities surrounding the Salton Sea have increased asthma prevalence versus the rest of California; however, a connection between dust inhalation and lung health impacts has not been defined.Methods: We used an established intranasal dust exposure murine model to study the lung inflammatory response following single or repetitive (7-day) exposure to extracts of dusts collected in regions surrounding the Salton Sea (SSDE), complemented with in vitro investigations assessing SSDE impacts on the airway epithelium.Results: In these investigations, single or repetitive SSDE exposure induced significant lung inflammatory cytokine release concomitant with neutrophil influx. Repetitive SSDE exposure led to significant lung eosinophil recruitment and altered expression of genes associated with allergen-mediated immune response, including Clec4e. SSDE treatment of human bronchial epithelial cells (BEAS-2B) induced inflammatory cytokine production at 5- and 24-hours post-treatment. When BEAS-2B were exposed to protease activity-depleted SSDE (PDSSDE) or treated with SSDE in the context of protease-activated receptor-1 and − 2 antagonism, inflammatory cytokine release was decreased. Furthermore, repetitive exposure to PDSSDE led to decreased neutrophil and eosinophilic influx and IL-6 release in mice compared to SSDE-challenged mice.Conclusion: These investigations demonstrate potent lung inflammatory responses and tissue remodeling in response to SSDE, in part due to environmental proteases found within the dusts. These studies provide the first evidence supporting a link between environmental dust exposure, protease-mediated immune activation, and respiratory disease in the Salton Sea region.Keywords: Salton Sea, dust exposure, lung inflammation, asthma, proteases, protease-activated receptors
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- 2021
21. $\pi$-yalli: un nouveau corpus pour le nahuatl
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Torres-Moreno, Juan-Manuel, Guzmán-Landa, Juan-José, Ranger, Graham, Garrido, Martha Lorena Avendaño, Figueroa-Saavedra, Miguel, Quintana-Torres, Ligia, González-Gallardo, Carlos-Emiliano, Pontes, Elvys Linhares, Morales, Patricia Velázquez, and Jiménez, Luis-Gil Moreno
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Computer Science - Computation and Language ,Computer Science - Artificial Intelligence - Abstract
The NAHU$^2$ project is a Franco-Mexican collaboration aimed at building the $\pi$-YALLI corpus adapted to machine learning, which will subsequently be used to develop computer resources for the Nahuatl language. Nahuatl is a language with few computational resources, even though it is a living language spoken by around 2 million people. We have decided to build $\pi$-YALLI, a corpus that will enable to carry out research on Nahuatl in order to develop Language Models (LM), whether dynamic or not, which will make it possible to in turn enable the development of Natural Language Processing (NLP) tools such as: a) a grapheme unifier, b) a word segmenter, c) a POS grammatical analyser, d) a content-based Automatic Text Summarization; and possibly, e) a translator translator (probabilistic or learning-based)., Comment: 9 pages, in French language, 2 figures
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- 2024
22. Looking for optimal materials for whispering gallery modes applications at the 2 $\mu$m window
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Velazquez-Ibarra, Lorena and Barranco, Juan
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Physics - Optics - Abstract
The diverse applications of whispering gallery modes in spherical microresonators are strongly related to the sphere size and material composition. Their design should therefore be optimized to ensure that parameters such as the quality factor and the free spectral range are maximized. Because of the imminent capacity crisis of the optical communication systems operating at the 1550 nm wavelength regime, it is time to explore optical communications at the 2 $\mu\mbox{m}$ wavelength window. In this work, we analytically investigate key resonator parameters - quality factor and free spectral range - as a function of wavelength, aiming to establish a methodology to help identify optimal materials for whispering gallery mode sensors, with special attention at the 2 $\mu\mbox{m}$ wavelength window. Specifically, we examine three materials: fused silica, AsSe chalcogenide glass and calcium fluoride, and we perform a comparison between them in order to identify the region in the parameter space of resonant wavelengths and sphere radius, $(\lambda_R,R$), where the WGM resonators are optimal at wavelengths $1.8 \mu\mbox{m}<\lambda<2.1 \mu\mbox{m}$., Comment: 13 pages; 8 figures
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- 2024
23. Perfect revivals of Rabi oscillations and hybrid Bell states in a trapped ion
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Torres, Juan Mauricio, Ventura-Velázquez, Christian, and Arellano-Melendez, Ivan
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Quantum Physics - Abstract
We show that perfect revivals of Rabi oscillations are possible, under certain conditions, in the population inversion of a trapped ion. Based on this property, we find that Schr\"odinger cat states of the atomic motion are naturally generated by the unitary dynamics. Using a pair of symmetric and antisymmetric Schr\"odinger cat states of the motion, together with an electronic excited or ground state, we find that the interaction leads to four orthonormal maximally entangled states of the two partitions, which we identify as Bell states. We also study a quadratic Kerr-type evolution that is possible for short interaction times., Comment: 9 pages, 7 figures
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- 2024
24. An invitation to Fibonacci digits
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Cheigh, Justin, Moura, Guilherme Zeus Dantas e, Duke, Jacob Lehmann, Mauro, Annika, McDonald, Zoe, Mello, Anna, Miller, Kayla, Miller, Steven J., and Iannuzzelli, Santiago Velazquez
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Mathematics - History and Overview ,Mathematics - Number Theory - Abstract
The purpose of this short note is to show the interplay between math outreach and conducting original research, in particular how each can build off the other., Comment: 9 pages, 5 figures
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- 2024
25. Impact of Device Resistances in the Performance of Graphene-based Terahertz Photodetectors
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Castelló, O., Baptista, Sofía M. López, Watanabe, K., Taniguchi, T., Diez, E., Velázquez-Pérez, J. E., Meziani, Y. M., Caridad, J. M., and Delgado-Notario, J. A.
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Condensed Matter - Mesoscale and Nanoscale Physics ,Physics - Instrumentation and Detectors - Abstract
In recent years, graphene Field-Effect-Transistors (GFETs) have demonstrated an outstanding potential for Terahertz (THz) photodetection due to their fast response and high-sensitivity. Such features are essential to enable emerging THz applications, including 6G wireless communications, quantum information, bioimaging and security. However, the overall performance of these photodetectors may be utterly compromised by the impact of internal resistances presented in the device, so-called access or parasitic resistances. In this work, we provide a detailed study of the influence of internal device resistances in the photoresponse of high-mobility dual-gate GFET detectors. Such dual-gate architectures allow us to fine tune (decrease) the internal resistance of the device by an order of magnitude and consequently demonstrate an improved responsivity and noise-equivalent-power values of the photodetector, respectively. Our results can be well understood by a series resistance model, as shown by the excellent agreement found between the experimental data and theoretical calculations. These findings are therefore relevant to understand and improve the overall performance of existing high-mobility graphene photodetectors.
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- 2024
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26. CA-SSLR: Condition-Aware Self-Supervised Learning Representation for Generalized Speech Processing
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Lu, Yen-Ju, Liu, Jing, Thebaud, Thomas, Moro-Velazquez, Laureano, Rastrow, Ariya, Dehak, Najim, and Villalba, Jesus
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Electrical Engineering and Systems Science - Audio and Speech Processing ,Computer Science - Computation and Language ,Computer Science - Machine Learning ,Computer Science - Sound - Abstract
We introduce Condition-Aware Self-Supervised Learning Representation (CA-SSLR), a generalist conditioning model broadly applicable to various speech-processing tasks. Compared to standard fine-tuning methods that optimize for downstream models, CA-SSLR integrates language and speaker embeddings from earlier layers, making the SSL model aware of the current language and speaker context. This approach reduces the reliance on input audio features while preserving the integrity of the base SSLR. CA-SSLR improves the model's capabilities and demonstrates its generality on unseen tasks with minimal task-specific tuning. Our method employs linear modulation to dynamically adjust internal representations, enabling fine-grained adaptability without significantly altering the original model behavior. Experiments show that CA-SSLR reduces the number of trainable parameters, mitigates overfitting, and excels in under-resourced and unseen tasks. Specifically, CA-SSLR achieves a 10% relative reduction in LID errors, a 37% improvement in ASR CER on the ML-SUPERB benchmark, and a 27% decrease in SV EER on VoxCeleb-1, demonstrating its effectiveness., Comment: 38th Conference on Neural Information Processing Systems (NeurIPS 2024)
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- 2024
27. Noncommutative Model Selection and the Data-Driven Estimation of Real Cohomology Groups
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Guzmán-Tristán, Araceli, Rieser, Antonio, and Velázquez-Richards, Eduardo
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Computer Science - Computational Geometry ,Computer Science - Machine Learning ,Mathematics - Algebraic Topology - Abstract
We propose three completely data-driven methods for estimating the real cohomology groups $H^k (X ; \mathbb{R})$ of a compact metric-measure space $(X, d_X, \mu_X)$ embedded in a metric-measure space $(Y,d_Y,\mu_Y)$, given a finite set of points $S$ sampled from a uniform distrbution $\mu_X$ on $X$, possibly corrupted with noise from $Y$. We present the results of several computational experiments in the case that $X$ is embedded in $\mathbb{R}^n$, where two of the three algorithms performed well., Comment: 15 pages, sequel to "Noncommutative Model Selection for Data Clustering and Dimension Reduction Using Relative von Neumann Entropy"
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- 2024
28. A Study of Malware Prevention in Linux Distributions
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Vu, Duc-Ly, Dunlap, Trevor, Obermeier-Velazquez, Karla, Gibert, Paul, Meyers, John Speed, and Torres-Arias, Santiago
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Computer Science - Cryptography and Security ,Computer Science - Software Engineering - Abstract
Malicious attacks on open source software packages are a growing concern. This concern morphed into a panic-inducing crisis after the revelation of the XZ Utils backdoor, which would have provided the attacker with, according to one observer, a "skeleton key" to the internet. This study therefore explores the challenges of preventing and detecting malware in Linux distribution package repositories. To do so, we ask two research questions: (1) What measures have Linux distributions implemented to counter malware, and how have maintainers experienced these efforts? (2) How effective are current malware detection tools at identifying malicious Linux packages? To answer these questions, we conduct interviews with maintainers at several major Linux distributions and introduce a Linux package malware benchmark dataset. Using this dataset, we evaluate the performance of six open source malware detection scanners. Distribution maintainers, according to the interviews, have mostly focused on reproducible builds to date. Our interviews identified only a single Linux distribution, Wolfi OS, that performs active malware scanning. Using this new benchmark dataset, the evaluation found that the performance of existing open-source malware scanners is underwhelming. Most studied tools excel at producing false positives but only infrequently detect true malware. Those that avoid high false positive rates often do so at the expense of a satisfactory true positive. Our findings provide insights into Linux distribution package repositories' current practices for malware detection and demonstrate the current inadequacy of open-source tools designed to detect malicious Linux packages., Comment: 14 pages, 3 figures, 11 tables
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- 2024
29. Extendibility of foliations
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Perrella, Pablo and Velazquez, Sebastián
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Mathematics - Algebraic Geometry ,14D15, 14D15, 14D06, 32S65, 32M25 - Abstract
Given a foliation $\mathcal{F}$ on $X$ and an embedding $X\subseteq Y$, is there a foliation on $Y$ extending $\mathcal{F}$? Using formal methods, we show that this question has an affirmative answer whenever the embedding is sufficiently positive with respect to $(X,\mathcal{F})$ and the singularities of $\mathcal{F}$ belong to a certain class. These tools also apply in the case where $Y$ is the total space of a deformation of $X$. Regarding the uniqueness of the extension, we prove a foliated version of a statement by Fujita and Grauert ensuring the existence of tubular neighborhoods. We also give sufficient conditions for a foliation to have only trivial unfoldings, generalizing a result due to G\'omez-Mont.
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- 2024
30. Spectral study of very high energy gamma rays from SS 433 with HAWC
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Alfaro, R., Alvarez, C., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Belmont-Moreno, E., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotzomi, J., De la Fuente, E., Depaoli, D., Di Lalla, N., Hernandez, R. Diaz, Dingus, B. L ., DuVernois, M. A., Engel, K., Ergin, T., Espinoza, C ., Fan, K. L., Fang, K., Fraija, N., Fraija, S., García-González, J. A., Muñoz, A. González, González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Hernández-Cadena, S., Herzog, I., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Kaufmann, S., Lara, A ., Lee, W. H., Lee, J., de León, C., Vargas, H. León, Longinotti, A. L., Luis-Raya, G., Malone, K., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Montes, J. A., Moreno, E., Mostafá, M., Nellen, L., Nisa, M. U ., Noriega-Papaqui, R ., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E ., Salazar, H., Sandoval, A., Schneider, M., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W ., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Varela, E ., Villaseñor, L., Wang, X., Wang, Z., Watson, I. J., Yu, S ., Yun-Cárcamo, S., and Zhou, H.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Very-high-energy (0.1-100 TeV) gamma-ray emission was observed in HAWC data from the lobes of the microquasar SS 433, making them the first set of astrophysical jets that were resolved at TeV energies. In this work, we update the analysis of SS 433 using 2,565 days of data from the High Altitude Water Cherenkov (HAWC) observatory. Our analysis reports the detection of a point-like source in the east lobe at a significance of $6.6\,\sigma$ and in the west lobe at a significance of $8.2\,\sigma$. For each jet lobe, we localize the gamma-ray emission and identify a best-fit position. The locations are close to the X-ray emission sites "e1" and "w1" for the east and west lobes, respectively. We analyze the spectral energy distributions and find that the energy spectra of the lobes are consistent with a simple power-law $\text{d}N/\text{d}E\propto E^{\alpha}$ with $\alpha = -2.44^{+0.13+0.04}_{-0.12-0.04}$ and $\alpha = -2.35^{+0.12+0.03}_{-0.11-0.03}$ for the east and west lobes, respectively. The maximum energy of photons from the east and west lobes reaches 56 TeV and 123 TeV, respectively. We compare our observations to various models and conclude that the very-high-energy gamma-ray emission can be produced by a population of electrons that were efficiently accelerated.
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- 2024
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31. Ultra-High-Energy Gamma-Ray Bubble around Microquasar V4641 Sgr
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Alfaro, R., Alvarez, C., Arteaga-Velázquez, J. C., Rojas, D. Avila, Solares, H. A. Ayala, Babu, R., Belmont-Moreno, E., Caballero-Mora, K. S., Capistrán, T., Carramiñana, A., Casanova, S., Cotti, U., Cotzomi, J., de León, S. Coutiño, De la Fuente, E., Depaoli, D., Di Lalla, N., Hernandez, R. Diaz, Dingus, B. L., DuVernois, M. A., Durocher, M., Díaz-Vélez, J. C., Engel, K., Espinoza, C., Fan, K. L., Fang, K., Fraija, N., Fraija, S., García-González, J. A., Garfias, F., Muñoz, A. Gonzalez, González, M. M., Goodman, J. A., Groetsch, S., Harding, J. P., Herzog, I., Hinton, J., Huang, D., Hueyotl-Zahuantitla, F., Hüntemeyer, P., Iriarte, A., Joshi, V., Kaufmann, S., Kieda, D., de León, C., Lee, J., Vargas, H. León, Linnemann, J. T., Longinotti, A. L., Luis-Raya, G., Malone, K., Martinez, O., Martínez-Castro, J., Matthews, J. A., Miranda-Romagnoli, P., Morales-Soto, J. A., Moreno, E., Mostafá, M., Nayerhoda, A., Nellen, L., Newbold, M., Nisa, M. U., Noriega-Papaqui, R., Olivera-Nieto, L., Omodei, N., Osorio, M., Araujo, Y. Pérez, Pérez-Pérez, E. G., Rho, C. D., Rosa-González, D., Ruiz-Velasco, E., Salazar, H., Salazar-Gallegos, D., Sandoval, A., Schneider, M., Serna-Franco, J., Smith, A. J., Son, Y., Springer, R. W., Tibolla, O., Tollefson, K., Torres, I., Torres-Escobedo, R., Turner, R., Ureña-Mena, F., Varela, E., Villaseñor, L., Wang, X., Watson, I. J., Willox, E., Yun-Cárcamo, S., and Zhou, H.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Microquasars are laboratories for the study of jets of relativistic particles produced by accretion onto a spinning black hole. Microquasars are near enough to allow detailed imaging of spatial features across the multiwavelength spectrum. The recent extension of the spatial morphology of a microquasar, SS 433, to TeV gamma rays \cite{abeysekara2018very} localizes the acceleration of electrons at shocks in the jet far from the black hole \cite{hess2024ss433}. Here we report TeV gamma-ray emission from another microquasar, V4641~Sgr, which reveals particle acceleration at similar distances from the black hole as SS~433. Additionally, the gamma-ray spectrum of V4641 is among the hardest TeV spectra observed from any known gamma-ray source and is detected up to 200 TeV. Gamma rays are produced by particles, either electrons or hadrons, of higher energies. Because electrons lose energy more quickly the higher their energy, such a spectrum either very strongly constrains the electron production mechanism or points to the acceleration of high-energy hadrons. This observation suggests that large-scale jets from microquasars could be more common than previously expected and that microquasars could be a significant source of Galactic cosmic rays. high energy gamma-rays also provide unique constraints on the acceleration mechanisms of extra-Galactic cosmic rays postulated to be produced by the supermassive black holes and relativistic jets of quasars. The distance to quasars limits imaging studies due to insufficient angular resolution of gamma-rays and due to attenuation of the highest energy gamma-rays by the extragalactic background light.
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- 2024
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32. Phase retrieval from short-time Fourier transform in LCA groups
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Accomazzo, Natalia, Carando, Daniel, Nores, Rocio, Paternostro, Victoria, and Velazquez, Sebastian
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Mathematics - Classical Analysis and ODEs ,43A70, 42C30, 94A20 - Abstract
We study the short-time Fourier transform phase retrieval problem in locally compact abelian groups. Using probabilistic methods, we show that for a large class of groups $G$ and compact subsets $K\subseteq G$ there exists a window function and a uniformly separated set in $G\times \widehat{G}$ allowing phase retrieval in $L^2(K)$.
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- 2024
33. Solvability of MHS equations with Grad-Rubin boundary conditions in general domains
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del Pino, Daniel Sánchez-Simón and Velázquez, Juan J. L.
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Mathematics - Analysis of PDEs ,Mathematical Physics - Abstract
In this paper we study the solvability of the magnetohydrostatic equations with Grad-Rubin boundary conditions in general domains. Earlier results for this problem were obtained in the recent years by D. Alonso-Or\'an and J. L. L. Vel\'azquez, where particularly simple geometries were considered. In this article we develop a theory that allows to solve these boundary value problems for a larger class of domains. We will give precise applications to more physically relevant situations, like the case of the space between two circumferences or spheres and domains close to them., Comment: 60 pages, 1 figure
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- 2024
34. Non-parametric reconstruction of cosmological observables using Gaussian Processes Regression
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Velázquez, José de Jesús, Escamilla, Luis A., Mukherjee, Purba, and Vázquez, J. Alberto
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Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The current accelerated expansion of the Universe remains ones of the most intriguing topics in modern cosmology, driving the search for innovative statistical techniques. Recent advancements in machine learning have significantly enhanced its application across various scientific fields, including physics, and particularly cosmology, where data analysis plays a crucial role in problem-solving. In this work, a non-parametric regression method with Gaussian processes is presented along with several applications to reconstruct some cosmological observables, such as the deceleration parameter and the dark energy equation of state, in order to contribute with some information that helps to clarify the behavior of the Universe. It was found that the results are consistent with $\Lambda$CDM and the predicted value of the Hubble parameter at redshift zero is $H_{0}=68.798\pm 6.340(1\sigma) \text{ km}\text{ s}^{-1}\text{ Mpc}^{-1}$., Comment: 21 pages, 19 figures, Universe 10 (2024) 12
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- 2024
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35. On multiplicative Jacobi polynomials and function approximation through multiplicative series
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Fuentes, Edinson, Garza, Luis E., and C, Fabián Velázquez
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Mathematics - Classical Analysis and ODEs ,42C05, 65D15 - Abstract
In this contribution, we introduce the multiplicative Jacobi polynomials that arise as one of the solutions of the multiplicative Sturm-Liouville equation \begin{equation*} \frac{d^*}{dx}\left( e^{(1-x^2)\omega(x)}\odot \frac{d^*y}{dx} \right)\oplus \left(e^{ n(n+\alpha+\beta+1)\omega(x)}\odot y\right)=1, \ x\in[-1,1], \end{equation*} where $\omega(x)=(1-x)^{\alpha}(1+x)^{\beta}$ with $\alpha, \beta >-1$ real numbers and $n$ is a non-negative integer number. We extend some properties of classical Jacobi polynomials to the multiplicative case. In particular, we present several properties of multiplicative Legendre polynomials and multiplicative Chebyshev polynomials of first and second kind. We also prove that every real and positive function can be expressed as a multiplicative Jacobi-Fourier series and show that such functions can be approximated by the corresponding partial products of these series. We illustrate the obtained results with some examples., Comment: 34 pages, 10 figures
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- 2024
36. Developing Learning Skills through Game-Based Learning in Complex Scenarios: A Case in Undergraduate Logistics Education
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Ernesto Pacheco-Velazquez, Virginia Rodés, and David Salinas-Navarro
- Abstract
This study investigates the impact of game-based learning (GBL), an increasingly popular educational approach, on the development of self-directed learning (SDL) skills in complex scenarios, particularly in undergraduate logistics education. A key component of the three year study is LOST (Logistics Education Simulator), a serious game platform, deployed in an undergraduate engineering course in Mexico. An extensive literature review was carried out using Scopus to examine recent works published between 2019 and 2024, providing a state-of-the-art overview of the field. Subsequently, a survey based on the scale created by Fisher, King, and Tague (2001), known for its extensively evaluated internal consistency, revealed five distinct factors of self-directed learning. The findings underscore that the LOST platform significantly enhances self-directed learning, promoting the development of Self-management Skills, Openness to Learning Opportunities, Initiative and Independence in Learning, Self-concept as an Effective Learner, and Love of Learning. The students demonstrated a significant increase in their perception of these skills over the course of the study, highlighting the effectiveness of GBL in promoting such learning skills. These findings highlight the multidimensional nature of learning skills that can be fostered through GBL. The study concludes by discussing the vital role of GBL in complex scenarios, particularly in enhancing the development of self-directed learning skills in undergraduate logistics education.
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- 2024
37. The comprehensive management of patients with rhino-orbito-cerebral mucormycosis; a perspective from antifungal treatment to prosthetic rehabilitation: A descriptive cohort study
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Castrejon, Angelica Julian, Hernandez Martinez, Rosa Marene, Mendez, Diana Rivero, Gil Velazquez, Israel Nayensei, Rodriguez Pina, Juan Heriberto, Salgado Camacho, Juan Manuel, Calva, Nicolas Teyes, Espindola Chavarria, Sayuri I, Meza-Meneses, Patricia A, and Castro-Fuentes, Carlos Alberto
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- 2024
38. Cultivating Community Cultural Wealth and Armed Love: Freedom School as a Vanguard
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Nancy Ares, Laura Cochell, Tyana Velazquez-Smith, and Jeremy Smith
- Abstract
We present a conceptual exploration of armed love as a component of liberatory pedagogy. We ground our work in community cultural wealth theory (CCW) that centers social capital often found in non-dominant communities under pressure. We argue that recognizing and working against exploitation using the community's social, cultural, and historical assets are central to liberatory pedagogy. Explicating the connections between armed love and CCW is a novel contribution to the field, as it has not been done before and it highlights how asset-based pedagogies that are grounded in love can act as a protective factor for students in a racist society.
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- 2024
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39. Intimate partner violence among HIV-positive women in Nairobi, Kenya
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Brooks RD, Jolly PE, Marsh L, Velazquez JM, Padilla L, and Jaoko WG
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intimate partner violence ,emotional abuse ,sexual violence ,physical violence ,controlling behavior ,violence against women ,Gynecology and obstetrics ,RG1-991 - Abstract
RD Brooks,1 PE Jolly,1 L Marsh,1 JM Velazquez,1 L Padilla,1 WG Jaoko21Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA; 2Department of Medical Microbiology, School of Medicine, University of Nairobi, Nairobi, KenyaCorrespondence: PE JollyDepartment of Epidemiology, University of Alabama at Birmingham, School of Public Health, 1665 University Boulevard, RPHB 217, Birmingham, Alabama 35294-0022, USATel +1 205 934 1823Fax +1 205 975 3329Email jollyp@uab.eduPurpose: This study was conducted to identify the prevalence and sociodemographic factors associated with four forms of intimate partner violence (IPV) among HIV-positive women attending the Comprehensive Care Centre at the Kenyatta National Hospital in Nairobi, Kenya.Methods: A cross-sectional study was conducted among 600 sexually active HIV-positive women aged 18–69 years from May to August of 2012. A structured questionnaire including questions pertaining to sociodemographic characteristics, health care decisions, and forms of IPV (controlling behavior, emotional abuse, physical violence, and sexual violence) was administered to each woman.Results: All women reported experiencing emotional abuse; 20%, 17%, and 15% experienced controlling behavior, physical violence, and sexual violence, respectively. Women who reported low/below average socioeconomic status (SES) had a greater likelihood of experiencing controlling behavior than women with high/average SES (adjusted odds ratio [aOR] =1.62, 95% CI 1.05–2.51). Women who were unemployed had greater odds of experiencing physical violence than those who were employed (aOR =2.35, 95% CI 1.31–4.23). Non-Christian women had higher odds of experiencing controlling behavior, physical violence, and sexual violence than Christian women (aOR =4.41, 95% CI 1.81–10.76 and aOR =3.33, 95% CI 1.43–7.80).Conclusion: Based on the prevalence of IPV and the sociodemographic factors identified to be associated with IPV among women in this study it may be beneficial to include IPV screening as part of routine clinic visits for HIV-positive and other women. Furthermore, women who report emotional abuse or controlling behavior from spouse should not be overlooked, as these two forms of IPV may precede or accompany physical and sexual IPV. Women who report experiencing IPV during clinic visits may be referred to organizations and resources available to battered women in Kenya. Increased funding for anti-IPV programs and changes in policy may also contribute to a reduction in IPV among HIV-positive and other women in Kenya.Keywords: intimate partner violence, emotional abuse, sexual violence, physical violence, controlling behavior, violence against women
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- 2019
40. Exposure to constant artificial light alters honey bee sleep rhythms and disrupts sleep.
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Kim, Ashley, Velazquez, Aura, Saavedra, Belen, Smarr, Benjamin, and Nieh, James
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Anthropogenic stressors ,Circadian rhythm ,Honey bee colony health ,Light pollution ,Sleep disturbances ,Animals ,Bees ,Sleep ,Circadian Rhythm ,Light ,Behavior ,Animal ,Photoperiod - Abstract
Artificial light at night (ALAN) changes animal behavior in multiple invertebrates and vertebrates and can result in decreased fitness. However, ALAN effects have not been studied in European honey bees (Apis mellifera), an important pollinator in which foragers show strong circadian rhythmicity. Colonies can be exposed to ALAN in swarm clusters, when bees cluster outside the nest on hot days and evenings, and, in limited cases, when they build nests in the open. We captured and maintained foragers in incubated cages and subjected them to constant light (LL), constant dark (DD), or 12 h light:12 h dark (LD) cycle, and observed them with infrared cameras. After 79 h, there was a significant interaction of treatment and time because LL bees slept less. In detail, the bees maintained a regular sleep pattern for three days but LL bees showed a shift on the fourth day. LL bees had the largest sleep differences from LD controls, with trends of lengthened periods and increased phase misalignment from both LD and DD bees. LL bees also experienced significantly more disturbances from their nestmates and preferred to sleep in the lower portion of the cages, which had significantly lower light intensity. These findings suggest that ALAN can disrupt the sleep of honey bee foragers, which has implications for their behavior and overall colony health.
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- 2024
41. NAB2::STAT6 fusions and genome-wide DNA methylation profiling: Predictors of patient outcomes in meningeal solitary fibrous tumors.
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Eschbacher, Kathryn, Tran, Quynh, Moskalev, Evgeny, Jenkins, Sarah, Fritchie, Karen, Stoehr, Robert, Caron, Alissa, Link, Michael, Brown, Paul, Guajardo, Andrew, Brat, Daniel, Wu, Ashley, Santagata, Sandro, Louis, David, Brastianos, Priscilla, Kaplan, Alexander, Alexander, Brian, Rossi, Sabrina, Ferrarese, Fabio, Raleigh, David, Nguyen, Minh, Gross, John, Velazquez Vega, Jose, Rodriguez, Fausto, Perry, Arie, Martinez-Lage, Maria, Orr, Brent, Haller, Florian, and Giannini, Caterina
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CNS WHO grade ,NAB2::STAT6 ,TERT ,meningeal solitary fibrous tumor ,solitary fibrous tumor ,Humans ,Female ,Male ,Middle Aged ,Solitary Fibrous Tumors ,DNA Methylation ,STAT6 Transcription Factor ,Adult ,Repressor Proteins ,Aged ,Meningeal Neoplasms ,Young Adult ,Adolescent ,Aged ,80 and over ,Child ,Prognosis ,Telomerase - Abstract
Meningeal solitary fibrous tumors (SFT) are rare and have a high frequency of local recurrence and distant metastasis. In a cohort of 126 patients (57 female, 69 male; mean age at surgery 53.0 years) with pathologically confirmed meningeal SFTs with extended clinical follow-up (median 9.9 years; range 15 days-43 years), we performed extensive molecular characterization including genome-wide DNA methylation profiling (n = 80) and targeted TERT promoter mutation testing (n = 98). Associations were examined with NAB2::STAT6 fusion status (n = 101 cases; 51 = ex5-7::ex16-17, 26 = ex4::ex2-3; 12 = ex2-3::exANY/other and 12 = no fusion) and placed in the context of 2021 Central Nervous System (CNS) WHO grade. NAB2::STAT6 fusion breakpoints (fusion type) were significantly associated with metastasis-free survival (MFS) (p = 0.03) and, on multivariate analysis, disease-specific survival (DSS) when adjusting for CNS WHO grade (p = 0.03). DNA methylation profiling revealed three distinct clusters: Cluster 1 (n = 38), Cluster 2 (n = 22), and Cluster 3 (n = 20). Methylation clusters were significantly associated with fusion type (p
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- 2024
42. Explainable Metrics for the Assessment of Neurodegenerative Diseases through Handwriting Analysis
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Thebaud, Thomas, Favaro, Anna, Chen, Casey, Chavez, Gabrielle, Moro-Velazquez, Laureano, Butala, Ankur, and Dehak, Najim
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Quantitative Biology - Neurons and Cognition ,Computer Science - Machine Learning - Abstract
Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a wide array of explainable metrics extracted from the handwriting signals of 113 subjects performing multiple tasks on a digital tablet, as part of the Neurological Signals dataset. The aim is to measure their effectiveness in characterizing NDs, including AD and PD. To this end, task-agnostic and task-specific metrics are extracted from 14 distinct tasks. Subsequently, through statistical analysis and a series of classification experiments, we investigate which metrics provide greater discriminative power between NDs and healthy controls and amongst different NDs. Preliminary results indicate that the tasks at hand can all be effectively leveraged to distinguish between the considered set of NDs, specifically by measuring the stability, the speed of writing, the time spent not writing, and the pressure variations between groups from our handcrafted explainable metrics, which shows p-values lower than 0.0001 for multiple tasks. Using various binary classification algorithms on the computed metrics, we obtain up to 87 % accuracy for the discrimination between AD and healthy controls (CTL), and up to 69 % for the discrimination between PD and CTL., Comment: 14 pages including references, under review in IEEE JHBI
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- 2024
43. Alternative Bell's states and teleportation
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Romero, Juan M., Montoya-Gonzalez, Emiliano, and Velazquez-Alvarado, Oscar
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Quantum Physics - Abstract
Bell's states are among the most useful in quantum computing. These state are an orthonormal base of entagled states with two qubits. We propose alternative bases of entangled states. Some of these states depend on a continuous parameter. We present the quantum circuit and code of these alternative bases. In addition, we study quantum teleportation with these entangled states and present their quantum circuits and codes associated., Comment: 39 pages, 15 figures, minor corrections. Comments welcome
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- 2024
44. Benchmarking the design of the cryogenics system for the underground argon in DarkSide-20k
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Collaboration, DarkSide-20k, Acerbi, F., Adhikari, P., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Angiolilli, M., Aprile, E., Ardito, R., Corona, M. Atzori, Auty, D. J., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Olmedo, A. Barrado, Barrillon, P., Batignani, G., Bhowmick, P., Blua, S., Bocci, V., Bonivento, W., Bottino, B., Boulay, M. G., Buchowicz, A., Bussino, S., Busto, J., Cadeddu, M., Cadoni, M., Calabrese, R., Camillo, V., Caminata, A., Canci, N., Capra, A., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castellani, A., Castello, P., Cavalcante, P., Cebrian, S., Ruiz, J. Cela, Chashin, S., Chepurnov, A., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Coadou, Y., Cocco, V., Colaiuda, D., Vilda, E. Conde, Consiglio, L., Costa, B. S., Czubak, M., D'Aniello, M., D'Auria, S., Rolo, M. D. Da Rocha, Darbo, G., Davini, S., De Cecco, S., De Guido, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Ludovico, A., Di Noto, L., Di Stefano, P., Dias, L. K., Mairena, D. Díaz, Ding, X., Dionisi, C., Dolganov, G., Dordei, F., Dronik, V., Elersich, A., Ellingwood, E., Erjavec, T., Diaz, M. Fernandez, Ficorella, A., Fiorillo, G., Franchini, P., Franco, D., Gatti, H. Frandini, Frolov, E., Gabriele, F., Gahan, D., Galbiati, C., Galiński, G., Gallina, G., Gallus, G., Garbini, M., Abia, P. Garcia, Gawdzik, A., Gendotti, A., Ghisi, A., Giovanetti, G. K., Casanueva, V. Goicoechea, Gola, A., Grandi, L., Grauso, G., di Cortona, G. Grilli, Grobov, A., Gromov, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A., Hamer, A., Haranczyk, M., Harrop, B., Hessel, T., Hill, S., Horikawa, S., Hu, J., Hubaut, F., Hucker, J., Hugues, T., Hungerford, E. V., Ianni, A., Ippolito, V., Jamil, A., Jillings, C., Jois, S., Kachru, P., Keloth, R., Kemmerich, N., Kemp, A., Kendziora, C. L., Kimura, M., Kish, A., Kondo, K., Korga, G., Kotsiopoulou, L., Koulosousas, S., Kubankin, A., Kunzé, P., Kuss, M., Kuźniak, M., Kuzwa, M., La Commara, M., Lai, M., Guirriec, E. Le, Leason, E., Leoni, A., Lidey, L., Lissia, M., Luzzi, L., Lychagina, O., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Marasciulli, A., Mari, S. M., Mariani, C., Maricic, J., Martinez, M., Martoff, C. J., Matteucci, G., Mavrokoridis, K., McDonald, A. B., Mclaughlin, J., Merzi, S., Messina, A., Milincic, R., Minutoli, S., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Murphy, M., Murra, M., Muscas, C., Musico, P., Nania, R., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikoloudaki, E., Nowak, J., Olchanski, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solórzano, A. Ortiz, Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Papi, D., Pastuszak, G., Paternoster, G., Peck, A., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Perez, R., Perotti, F., Pesudo, V., Piacentini, S. I., Pino, N., Plante, G., Pocar, A., Poehlmann, M., Pordes, S., Pralavorio, P., Price, D., Puglia, S., Bazetto, M. Queiroga, Ragusa, F., Ramachers, Y., Ramirez, A., Ravinthiran, S., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Rivetti, A., Roberts, A., Roberts, C., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Rudik, D., Sabia, M., Salomone, P., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Santos, E. M., Savarese, C., Scapparone, E., Schillaci, G., Schuckman II, F. G., Scioli, G., Semenov, D. A., Shalamova, V., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sotnikov, A., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Sulis, S., Sung, A., Sunny, C., Suvorov, Y., Szelc, A. M., Taborda, O., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thompson, A., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil, T. J., Van Uffelen, M., Velazquez-Fernandez, L., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Vyas, B., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wojaczyński, R., Wojcik, M., Wojcik, M. M., Wright, T., Xiao, X., Xie, Y., Yang, C., Yin, J., Zabihi, A., Zakhary, P., Zani, A., Zhang, Y., Zhu, T., Zichichi, A., Zuzel, G., and Zykova, M. P.
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Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
DarkSide-20k (DS-20k) is a dark matter detection experiment under construction at the Laboratori Nazionali del Gran Sasso (LNGS) in Italy. It utilises ~100 t of low radioactivity argon from an underground source (UAr) in its inner detector, with half serving as target in a dual-phase time projection chamber (TPC). The UAr cryogenics system must maintain stable thermodynamic conditions throughout the experiment's lifetime of over 10 years. Continuous removal of impurities and radon from the UAr is essential for maximising signal yield and mitigating background. We are developing an efficient and powerful cryogenics system with a gas purification loop with a target circulation rate of 1000 slpm. Central to its design is a condenser operated with liquid nitrogen which is paired with a gas heat exchanger cascade, delivering a combined cooling power of more than 8 kW. Here we present the design choices in view of the DS-20k requirements, in particular the condenser's working principle and the cooling control, and we show test results obtained with a dedicated benchmarking platform at CERN and LNGS. We find that the thermal efficiency of the recirculation loop, defined in terms of nitrogen consumption per argon flow rate, is 95 % and the pressure in the test cryostat can be maintained within $\pm$(0.1-0.2) mbar. We further detail a 5-day cool-down procedure of the test cryostat, maintaining a cooling rate typically within -2 K/h, as required for the DS-20k inner detector. Additionally, we assess the circuit's flow resistance, and the heat transfer capabilities of two heat exchanger geometries for argon phase change, used to provide gas for recirculation. We conclude by discussing how our findings influence the finalisation of the system design, including necessary modifications to meet requirements and ongoing testing activities., Comment: 44 pages, 25 figures, 1 table. Updated to match the published journal version
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- 2024
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45. Supportive Supervision for a Better Child Welfare Work Environment
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Velázquez, Jorge
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- 2024
46. Extrinsic Fluctuations in the p53 Cycle
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Hernández-García, Manuel Eduardo, Gómez-Schiavon, Mariana, and Velázquez-Castro, Jorge
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Quantitative Biology - Molecular Networks ,92-10, 62L20, 92C45 ,G.3 - Abstract
Fluctuations are inherent to biological systems, arising from the stochastic nature of molecular interactions, and influence various aspects of system behavior, stability, and robustness. These fluctuations can be categorized as intrinsic, stemming from the system's inherent structure and dynamics, and extrinsic, arising from external factors, such as temperature variations. Understanding the interplay between these fluctuations is crucial for obtaining a comprehensive understanding of biological phenomena. However, studying these effects poses significant computational challenges. In this study, we used an underexplored methodology to analyze the effect of extrinsic fluctuations in stochastic systems using ordinary differential equations instead of solving the Master Equation with stochastic parameters. By incorporating temperature fluctuations into reaction rates, we explored the impact of extrinsic factors on system dynamics. We constructed a master equation and calculated the equations for the dynamics of the first two moments, offering computational efficiency compared with directly solving the chemical master equation. We applied this approach to analyze a biological oscillator, focusing on the p53 model and its response to temperature-induced extrinsic fluctuations. Our findings underscore the impact of extrinsic fluctuations on the nature of oscillations in biological systems, with alterations in oscillatory behavior depending on the characteristics of extrinsic fluctuations. We observed an increased oscillation amplitude and frequency of the p53 concentration cycle. This study provides valuable insights into the effects of extrinsic fluctuations on biological oscillations and highlights the importance of considering them in more complex systems to prevent unwanted scenarios related to health issues., Comment: 21 pages, 9 figures
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- 2024
47. Exact Solutions for Small Systems: Urns Models
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Hernández-García, Manuel Eduardo and Velázquez-Castro, Jorge
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Condensed Matter - Statistical Mechanics ,Mathematics - Probability ,60 ,G.3 - Abstract
In this study, we analyzed urn models by solving the discrete-time master equation using an expansion in moments. This approach is a viable alternative to conventional methods, such as system-size expansion, allowing for the determination of analytical expressions for the mean and variance in an exact form and thus valid for any system size. In particular, this approach was used to study Bernoulli-Laplace and Ehrenfest urns, for which analytic expressions describing their evolution were found. This approach and the results will contribute to a more comprehensive understanding of stochastic systems and statistical physics for small-sized systems, where the thermodynamic limit cannot be assumed., Comment: 6 pages, 5 figures
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- 2024
48. Variations on distributed belief
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Lindqvist, John, Velázquez-Quesada, Fernando R., and Ågotnes, Thomas
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Computer Science - Logic in Computer Science - Abstract
Motivated by the search for forms of distributed belief that do not collapse in the face of conflicting information, this paper introduces the notions of cautious and bold distributed belief. Both notions rely on maximally consistent subgroups of agents, with cautious quantifying universally and bold quantifying existentially. As a result, while the cautious distributed belief of a group is inconsistent only when all group members are individually inconsistent, the bold distributed belief of a group is never inconsistent. The paper discusses these two notions, presenting their respective modalities and semantic interpretations, discussing some of their basic properties, studying whether they preserve doxastic properties from the members of the group, and comparing them not only with standard distributed belief but also with one another, both at the level of modalities and at the level of language expressivity.
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- 2024
49. Beyond spectral resolution in optical sensing: Picometer-level precision with multispectral readout
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Cano-Velázquez, M. S., Buntinx, S., Hendriks, A. L., Van Klinken, A., Li, C., Heijnen, B. J., Dolci, M., Picelli, L., Abdelkhalik, M. S., Sevo, P., Petruzzella, M., Pagliano, F., Hakkel, K. D., van Elst, D. M. J., van Veldhoven, P. J., Verhagen, E., Zijlstra, P., and Fiore, A.
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Physics - Optics ,Physics - Instrumentation and Detectors - Abstract
Optical sensors offer precision, remote read-out, and immunity to electromagnetic interference but face adoption challenges due to complex and costly readout instrumentation, mostly based on high-resolution. This article challenges the notion that high spectral resolution is necessary for high performance optical sensing. We propose co-optimizing the linewidths of sensor and readout to achieve picometer-level precision using low-resolution multispectral detector arrays and incoherent light sources. This approach is validated in temperature sensing, fiber-tip refractive index sensing, and biosensing, achieving superior precision to high-resolution spectrometers. This paradigm change in readout will enable optical sensing systems with costs and dimensions comparable to electronic sensors.
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- 2024
50. Large-scale cosmic ray anisotropies with 19 years of data from the Pierre Auger Observatory
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The Pierre Auger Collaboration, Halim, A. Abdul, Abreu, P., Aglietta, M., Allekotte, I., Cheminant, K. Almeida, Almela, A., Aloisio, R., Alvarez-Muñiz, J., Ambrosone, A., Yebra, J. Ammerman, Anastasi, G. A., Anchordoqui, L., Andrada, B., Dourado, L. Andrade, Andringa, S., Apollonio, L., Aramo, C., Ferreira, P. R. Araújo, Arnone, E., Velázquez, J. C. Arteaga, Assis, P., Avila, G., Avocone, E., Bakalova, A., Barbato, F., Mocellin, A. Bartz, Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Bianciotto, M., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Arbeletche, L. Bonneau, Borodai, N., Brack, J., Orchera, P. G. Brichetto, Briechle, F. L., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Cabana-Freire, S., Caccianiga, L., Campuzano, F., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Čermáková, B., Cermenati, A., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cerutti, A. C. Cobos, Colalillo, R., Conceição, R., Condorelli, A., Consolati, G., Conte, M., Convenga, F., Santos, D. Correia dos, Costa, P. J., Covault, C. E., Cristinziani, M., Sanchez, C. S. Cruz, Dasso, S., Daumiller, K., Dawson, B. R., de Almeida, R. M., de Errico, B., de Jesús, J., de Jong, S. J., Neto, J. R. T. de Mello, De Mitri, I., de Oliveira, J., Franco, D. de Oliveira, de Palma, F., de Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Denner, N., Deval, L., di Matteo, A., Dobrigkeit, C., D'Olivo, J. C., Mendes, L. M. Domingues, Dorosti, Q., Anjos, J. C. dos, Anjos, R. C. dos, Ebr, J., Ellwanger, F., Emam, M., Engel, R., Epicoco, I., Erdmann, M., Etchegoyen, A., Evoli, C., Falcke, H., Farrar, G., Fauth, A. C., Fehler, T., Feldbusch, F., Fernandes, A., Fick, B., Figueira, J. M., Filip, P., Filipčič, A., Fitoussi, T., Flaggs, B., Fodran, T., Freitas, M., Fujii, T., Fuster, A., Galea, C., García, B., Gaudu, C., Ghia, P. L., Giaccari, U., Gobbi, F., Gollan, F., Golup, G., Berisso, M. Gómez, Vitale, P. F. Gómez, Gongora, J. P., González, J. M., González, N., Góra, D., Gorgi, A., Gottowik, M., Guarino, F., Guedes, G. P., Guido, E., Gülzow, L., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harvey, V. M., Haungs, A., Hebbeker, T., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Jilek, V., Jurysek, J., Kampert, K. -H., Keilhauer, B., Khakurdikar, A., Covilakam, V. V. Kizakke, Klages, H. O., Kleifges, M., Knapp, F., Köhler, J., Krieger, F., Kubatova, M., Kunka, N., Lago, B. L., Langner, N., de Oliveira, M. A. Leigui, Lema-Capeans, Y., Letessier-Selvon, A., Lhenry-Yvon, I., Lopes, L., Lundquist, J. P., Payeras, A. Machado, Mandat, D., Manning, B. C., Mantsch, P., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Bravo, O. Martínez, Martins, M. A., Mathes, H. -J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Meinert, J., Melo, D., Menshikov, A., Merx, C., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Mulrey, K., Mussa, R., Namasaka, W. M., Negi, S., Nellen, L., Nguyen, K., Nicora, G., Niechciol, M., Nitz, D., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Panja, S., Parente, G., Paulsen, T., Pawlowsky, J., Pech, M., Pękala, J., Pelayo, R., Pelgrims, V., Pereira, L. A. S., Martins, E. E. Pereira, Bertolli, C. Pérez, Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Shahvar, M. Pourmohammad, Privitera, P., Prouza, M., Querchfeld, S., Rautenberg, J., Ravignani, D., Akim, J. V. Reginatto, Reuzki, A., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodriguez, E., Rojo, J. Rodriguez, Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Sampathkumar, P., Gomez, J. D. Sanabria, Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Sedoski, A., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Simkova, K., Simon, F., Šmída, R., Sommers, P., Squartini, R., Stadelmaier, M., Stanič, S., Stasielak, J., Stassi, P., Strähnz, S., Straub, M., Suomijärvi, T., Supanitsky, A. D., Svozilikova, Z., Szadkowski, Z., Tairli, F., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Peixoto, C. J. Todero, Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Tueros, M., Unger, M., Uzeiroska, R., Vaclavek, L., Vacula, M., Galicia, J. F. Valdés, Valore, L., Varela, E., Vašíčková, V., Vásquez-Ramírez, A., Veberič, D., Quispe, I. D. Vergara, Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Weitz, M., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yue, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., and Zavrtanik, M.
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Astrophysics - High Energy Astrophysical Phenomena - Abstract
Results are presented for the measurement of large-scale anisotropies in the arrival directions of ultra-high-energy cosmic rays detected at the Pierre Auger Observatory during 19 years of operation, prior to AugerPrime, the upgrade of the Observatory. The 3D dipole amplitude and direction are reconstructed above $4\,$EeV in four energy bins. Besides the established dipolar anisotropy in right ascension above $8\,$EeV, the Fourier amplitude of the $8$ to $16\,$EeV energy bin is now also above the $5\sigma$ discovery level. No time variation of the dipole moment above $8\,$EeV is found, setting an upper limit to the rate of change of such variations of $0.3\%$ per year at the $95\%$ confidence level. Additionally, the results for the angular power spectrum are shown, demonstrating no other statistically significant multipoles. The results for the equatorial dipole component down to $0.03\,$EeV are presented, using for the first time a data set obtained with a trigger that has been optimized for lower energies. Finally, model predictions are discussed and compared with observations, based on two source emission scenarios obtained in the combined fit of spectrum and composition above $0.6\,$EeV., Comment: Minor typo in table 4 corrected
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- 2024
- Full Text
- View/download PDF
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