164 results on '"Verkaik, Nicole S."'
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2. Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests
3. Functional Homologous Recombination (HR) Screening Shows the Majority of BRCA1/2 -Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient.
4. Supplemental legend from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
5. Figure S3 from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
6. Table S1, Table S2, Table S3 from Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
7. Data from A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
8. Supplementary Data from A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
9. Ex Vivo Functional Assay for Evaluating Treatment Response in Tumor Tissue of Head and Neck Squamous Cell Carcinoma
10. DNA-PKcs inhibitors sensitize neuroendocrine tumor cells to peptide receptor radionuclide therapy in vitro and in vivo
11. XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination
12. Abstract 805: RECAP (REpair CAPacity) identifies a subset of breast cancers unable to form RAD51 foci which are undetected by DNA-based BRCAness tests
13. Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity
14. In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib.
15. Functional Ex Vivo Tissue-Based Chemotherapy Sensitivity Testing for Breast Cancer
16. A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
17. Dynamic Assembly of End-Joining Complexes Requires Interaction between Ku70/80 and XRCC4
18. An XRCC4 Splice Mutation Associated With Severe Short Stature, Gonadal Failure, and Early-Onset Metabolic Syndrome
19. Preclinical Assessment of the Combination of PSMA-Targeting Radionuclide Therapy with PARP Inhibitors for Prostate Cancer Treatment.
20. A DNA-PKcs mutation in a radiosensitive [T.sup.-][B.sup.-] SCID patient inhibits Artemis activation and nonhomologous end-joining
21. Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.
22. Inter and intra-tumor somatostatin receptor 2 heterogeneity influences peptide receptor radionuclide therapy response
23. C-Terminal Extensions of Ku70 and Ku80 Differentially Influence DNA End Binding Properties
24. Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells
25. Direct Ex Vivo Observation of Homologous Recombination Defect Reversal After DNA-Damaging Chemotherapy in Patients With Metastatic Breast Cancer
26. A DNA-PKcs mutation in a radiosensitive T−B− SCID patient inhibits Artemis activation and nonhomologous end-joining
27. A new type of radiosensitive T−B−NK+severe combined immunodeficiency caused by a LIG4 mutation
28. End-joining of blunt DNA double-strand breaks in mammalian fibroblasts is precise and requires DNA-PK and XRCC4
29. The role of DNA dependent protein kinase in synapsis of DNA ends
30. Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre–B-cell receptor checkpoint in bone marrow
31. Correction: Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
32. Functional Ex Vivo Assay Reveals Homologous Recombination Deficiency in Breast Cancer Beyond BRCA Gene Defects
33. The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins
34. Silencing of CD44 Expression in Prostate Cancer by Hypermethylation of the CD44 Promoter Region
35. N-terminal truncated human RAG1 proteins can direct T-cell receptor but not immunoglobulin gene rearrangements
36. Tumor slice culture system to assess drug response of primary breast cancer
37. AnXRCC4Splice Mutation Associated With Severe Short Stature, Gonadal Failure, and Early-Onset Metabolic Syndrome
38. Attenuated XPC Expression Is Not Associated with Impaired DNA Repair in Bladder Cancer
39. Abstract 2425: Exploiting DNA repair defects in breast cancer
40. Functional Ex Vivo Assay to Select Homologous Recombination–Deficient Breast Tumors for PARP Inhibitor Treatment
41. The role of DNA dependent protein kinase in synapsis of DNA ends
42. A novel radiosensitive SCID patient with a pronounced G2/M sensitivity
43. NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication
44. MicroRNA responses and stress granule formation modulate the DNA damage response
45. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
46. The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends
47. A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining
48. Defective Artemis nuclease is characterized by coding joints with microhomology in long palindromic-nucleotide stretches
49. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells
50. Down-regulation of CD44 expression in human prostatic carcinoma cell lines is correlated with DNA hypermethylation
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