769 results on '"Verma, Chandra S."'
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2. Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists
3. Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities
4. Designer co-beta-peptide copolymer selectively targets resistant and biofilm Gram-negative bacteria
5. Desmoplakin CSM models unravel mechanisms regulating the binding to intermediate filaments and putative therapeutics for cardiocutaneous diseases
6. Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex
7. Author Correction: High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer
8. High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer
9. Molecular Mechanism of P53 Peptide Permeation through Lipid Membranes from Solid-State NMR Spectroscopy and Molecular Dynamics Simulations.
10. List of contributors
11. Stapled peptidomimetic therapeutics
12. The nanotube express: Delivering a stapled peptide to the cell surface
13. Coarse-Grained Model of Glycosaminoglycans for Biomolecular Simulations
14. Mechanisms of biased agonism by Gα i/o -biased stapled peptide agonists of the relaxin-3 receptor
15. Dissecting the geometric and hydrophobic constraints of stapled peptides
16. Three-dimensional structure of Megabalanus rosa Cement Protein 20 revealed by multi-dimensional NMR and molecular dynamics simulations
17. DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11
18. Decreased GLUT2 and glucose uptake contribute to insulin secretion defects in MODY3/HNF1A hiPSC-derived mutant β cells
19. PhosIDP: a web tool to visualize the location of phosphorylation sites in disordered regions
20. The role of molecular simulations in understanding the mechanisms of cell-penetrating peptides
21. An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin
22. Mechanisms of biased agonism by Gαi/o-biased stapled peptide agonists of the relaxin-3 receptor.
23. Elucidating the Effect of Polyethylene Terephthalate Chain Structure on Its Enzymatic Degradation Behavior
24. Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide
25. Molecular descriptors suggest stapling as a strategy for optimizing membrane permeability of cyclic peptides.
26. Prion and Water: Tight and Dynamical Hydration Sites Have a Key Role in Structural Stability
27. Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils
28. A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays
29. Data from TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
30. Supplementary Figures from TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
31. Supplementary Tables from TRK xDFG Mutations Trigger a Sensitivity Switch from Type I to II Kinase Inhibitors
32. Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation
33. A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma
34. Kinetic and thermodynamic effects of phosphorylation on p53 binding to MDM2
35. DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11.
36. Stapled peptide design: principles and roles of computation
37. Design-Rules for Stapled Alpha-Helical Peptides with On-Target In Vivo Activity: Application to Mdm2/X dual antagonists
38. Structome: Exploring the structural neighbourhood of proteins
39. Covalent Rescue of Mutant p53
40. Structome: a tool for the rapid assembly of datasets for structural phylogenetics
41. Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein
42. JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1
43. Exploiting Protein Intrinsic Flexibility in Drug Design
44. Development and application of a transcriptional sensor for detection of heterologous acrylic acid production in E. coli
45. Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides
46. Enrichment of charge-absent regions in phase separated proteins
47. Activation of p53: How phosphorylated Ser15 triggers sequential phosphorylation of p53 at Thr18 by CK1δ
48. Binding of Buried Structural Water Increases the Flexibility of Proteins
49. Exploitation of dihydroorotate dehydrogenase (DHODH) and p53 activation as therapeutic targets: A case study in polypharmacology
50. Abstract 5239: Switching inhibitor class overcomes crizotinib resistance in a MET fusion-positive NSCLC with a novel acquired MET G1090A mutation
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