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4 results on '"Veronica Gendelman"'

1. International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors

Author

Karin Magnussen, J. N. S. Leung, Mie Topholm Bruun, Emanuele Di Angelantonio, Mindy Goldman, Pierre Tiberghien, Jennifer McKay, Katja van den Hurk, Geneviève Woimant, Maria Kvist, David J. Roberts, Joanna Speedy, Minoko Takanashi, Roberta Fachini, Mahtab Maghsudlu, Johanna Castrén, Nancy Robitaille, Amy McMahon, Silvano Wendel, Eilat Shinar, Marj Bravo, Lise Sofie H. Nissen-Meyer, Hany Kamel, Mary Townsend, Miquel Lozano, Franke A. Quee, Jo Wiersum, Nancy M. Dunbar, Kathleen M. Grima, Veronica Gendelman, Jessyka Deschênes, Hana Raz, Pascal Morel, Cheuk-Kwong Lee, Public and occupational health, and Neurology

Subjects
medicine.medical_specialty, business.industry, medicine, MEDLINE, Hematology, General Medicine, Intensive care medicine, business, Whole blood
Published
2021

2. Qualifying coronavirus disease 2019 convalescent plasma donors in Israel

Author

Oren Zimhony, Sharron Bransburg-Zabary, Eilat Shinar, Marina Izak, Roni Gat, Veronica Gendelman, Boaz Lev, Jacob Chen, Daniel Cohen, Evgeniy Stoyanov, Yasmin Maor, and Avi Benov

Subjects
medicine.medical_specialty, Convalescent plasma, Coronavirus disease 2019 (COVID-19), Blood Donors, 030204 cardiovascular system & hematology, Asymptomatic, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Medicine, Humans, antibodies, In patient, Israel, Volunteer, donors, COVID-19 Serotherapy, Therapeutic strategy, biology, business.industry, SARS-CoV-2, Immunization, Passive, COVID-19, Hematology, General Medicine, Original Articles, Immunization, convalescent plasma, biology.protein, Original Article, medicine.symptom, Antibody, business, 030215 immunology
Abstract

Background and Objectives Passive immunization using investigational COVID‐19 convalescent plasma (CCP) is a promising therapeutic strategy and could improve outcome if transfused early and contain high levels of anti‐SARS‐CoV‐2 antibodies. We report the management of a national CCP collection and distribution program in Israel. Materials and Methods From 1 April 2020 to 15 January 2021, 4020 volunteer donors donated 5221 CCP units and 837 (20.8%) donors donated more than once. Anti‐nucleocapsid IgG antibodies were determined using chemiluminescent immunoassay method (Abbott). A statistical model based on repeated IgG tests in sequential donations was created to predict the time of antibody decline below sample/cut‐off (S/CO) level of 4.0. Results Ninety‐six percent of CCP donors suffered a mild disease or were asymptomatic. Older donors had higher antibody levels. Higher antibody levels (S/CO ≥4) were detected in 35.2% of the donors. Low positive (S/CO ≥1.4–3.99) were found in 37%, and 27.8% had undetectable antibodies (S/CO ≤1.4). The model predicted decrease antibody thresholds of 0.55%/day since the first CCP donation, providing guidance for the effective timing of future collections from donors with high antibody levels. Conclusions An efficient CCP collection and distribution program was achieved, based on performing initial and repeated plasma collections, preferably from donors with higher antibody levels, and only antibody‐rich units were supplied for therapeutic use. The inventory met the quantity and quality standards of the authorities, enabled to respond to the growing demand of the medical system and provide a product that may contribute to improve prognosis in patients with COVID‐19.

Published
2021

3. Vox Sanguinis International Forum on Mitigation Strategies to Prevent Faint and Pre-faint Adverse Reactions in Whole Blood Donors:Summary

Author

Mindy Goldman, Mary Townsend, Karin Magnussen, Miquel Lozano, Lise Sofie Nissen‐Meyer, Cheuk Kwong Lee, Jennifer Ngar‐Sze Leung, Minoko Takanashi, Jennifer McKay, Maria Kvist, Nancy Robitaille, Jessyka Deschênes, Emanuele Di Angelantonio, Amy McMahon, David Roberts, Mahtab Maghsudlu, Johanna Castrén, Pierre Tiberghien, Genevieve Woimant, Pascal Morel, Harry Kamel, Marjorie Bravo, Eilat Shinhar, Veronica Gendelman, Hana Raz, Silvano Wendel, Roberta Fachini, Franke Quee, Katja van den Hurk, Jo Wiersum, Kathleen Grima, Joanna Speedy, Mie Bruun, Nancy Dunbar, Public and occupational health, and Neurology

Subjects
medicine.medical_specialty, business.industry, MEDLINE, medicine, Hematology, General Medicine, Intensive care medicine, business, Whole blood
Published
2021

4. International Forum regarding practices related to donor haemoglobin and iron

Author

Manish J. Gandhi, André Lebrun, Jed B. Gorlin, Hany Kamel, Harvey G. Klein, J. Faed, J. Chay, Anne F. Eder, Giovani Vandewalle, Johanna Castrén, Whitney R. Steele, Vered Yahalom, D. Teo, Andreas Holbro, Gilles Delage, Rachid Djoudi, Joanne Pink, Veronica Gendelman, Michael J. Germain, J. N. S. Leung, Laura Infanti, Anthony J. Keller, Anne-Marie Fillet, Miquel Lozano, C. C. Y. Chu, Andreas Buser, Gail Miflin, Karin Magnussen, Eilat Shinar, Ralph R. Vassallo, Geneviève Woimant, E. M. O'Neill, Cheuk-Kwong Lee, Kamille A. West, Veerle Compernolle, Hwee Huang Tan, K. van den Hurk, Mindy Goldman, Joanna Speedy, Pierre Robillard, J. M. Cardenas, and Public and occupational health

Subjects
education.field_of_study, medicine.medical_specialty, Anemia, business.industry, Population, MEDLINE, Hematology, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, Surgery, 03 medical and health sciences, 0302 clinical medicine, Donation, Family medicine, medicine, education, business, 030215 immunology
Published
2016

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