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1,008 results on '"Vessella, Robert L."'

1. Targeting FOXAI-mediated repression of TGF-[beta] signaling suppresses castration-resistant prostate cancer progression

Author

Song, Bing, Park, Su-Hong, Zhao, Jonathan C., Fong, Ka-Wing, Li, Shangze, Lee, Yongik, Yang, Yeqing A., Sridhar, Subhasree, Lu, Xiaodong, Abdulkadir, Sarki A., Vessella, Robert L., Morrissey, Colm, Kuzel, Timothy M., Catalona, William, Yang, Ximing, and Yu, Jindan

Subjects
Cellular signal transduction -- Research, Drug resistance -- Research, Enzalutamide -- Dosage and administration, Prostate cancer -- Development and progression -- Drug therapy, Transforming growth factors -- Research, Antiandrogens, DNA microarrays, Bone morphogenetic proteins, Occupancy, Stem cells, Tumors, Genes, Cancer metastasis, Transcription (Genetics), B cells, Health care industry
Abstract

Prostate cancer (PC) progressed to castration resistance (CRPC) is a fatal disease. CRPC tumors develop resistance to new-generation antiandrogen enzalutamide through lineage plasticity, characterized by epithelial-mesenchymal transition (EMT) and a basal-like phenotype. FOXA1 is a transcription factor essential for epithelial lineage differentiation. Here, we demonstrate that FOXA1 loss leads to remarkable upregulation of transforming growth factor beta 3 (TGFB3), which encodes a ligand of the TGF-[beta] pathway. Mechanistically, this is due to genomic occupancy of FOXA1 on an upstream enhancer of the TGFB3 gene to directly inhibit its transcription. Functionally, FOXA1 downregulation induces TGF-[beta] signaling, EMT, and cell motility, which is effectively blocked by the TGF-[beta] receptor I inhibitor galunisertib (LY2157299). Tissue microarray analysis confirmed reduced levels of FOXA1 protein and a concordant increase in TGF-[beta] signaling, indicated by SMAD2 phosphorylation, in CRPC as compared with primary tumors. Importantly, combinatorial LY2157299 treatment sensitized PC cells to enzalutamide, leading to synergistic effects in inhibiting cell invasion in vitro and xenograft CRPC tumor growth and metastasis in vivo. Therefore, our study establishes FOXA1 as an important regulator of lineage plasticity mediated in part by TGF-[beta] signaling, and supports a novel therapeutic strategy to control lineage switching and potentially extend clinical response to antiandrogen therapies., Introduction Prostate cancer (PC) is the third leading cause of cancer-related death among men in the United States, where 1 in 8 men are expected to be diagnosed with PC [...]

Published
2019
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2. Prostate cancer cell phenotypes based on AGR2 and CD10 expression

Author

Ho, Melissa E, Quek, Sue-Ing, True, Lawrence D, Morrissey, Colm, Corey, Eva, Vessella, Robert L, Dumpit, Ruth, Nelson, Peter S, Maresh, Erin L, Mah, Vei, Alavi, Mohammed, Kim, Sara R, Bagryanova, Lora, Horvath, Steve, Chia, David, Goodglick, Lee, and Liu, Alvin Y

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Urologic Diseases, Prostate Cancer, Animals, Biomarkers, Tumor, Bone Neoplasms, Carcinoma, Disease-Free Survival, Heterografts, Humans, Immunohistochemistry, Immunophenotyping, Kaplan-Meier Estimate, Lymphatic Metastasis, Male, Mice, Mice, Inbred BALB C, Mice, Nude, Mucoproteins, Multivariate Analysis, Neoplasm Grading, Neoplasm Recurrence, Local, Neoplasm Transplantation, Neprilysin, Oncogene Proteins, Phenotype, Proportional Hazards Models, Prostatic Neoplasms, Proteins, Risk Factors, Time Factors, Tissue Array Analysis, AGR2, bone and soft tissue metastases, cancer cell phenotypes, CD10, patient stratification, prostate cancer, xenografts, Medical and Health Sciences, Pathology, Clinical sciences
Abstract

The combination of expression patterns of AGR2 (anterior gradient 2) and CD10 by prostate cancer provided four phenotypes that correlated with clinical outcome. Based on immunophenotyping, CD10(low)AGR2(high), CD10(high)AGR2(high), CD10(low)AGR2(low), and CD10(high)AGR2(low) were distinguished. AGR2(+) tumors were associated with longer recurrence-free survival and CD10(+) tumors with shorter recurrence-free survival. In high-stage cases, the CD10(low)AGR2(high) phenotype was associated with a ninefold higher recurrence-free survival than the CD10(high)AGR2(low) phenotype. The CD10(high)AGR2(high) and CD10(low)AGR2(low) phenotypes were intermediate. The CD10(high)AGR2(low) phenotype was most frequent in high-grade primary tumors. Conversely, bone and other soft tissue metastases, and derivative xenografts, expressed more AGR2 and less CD10. AGR2 protein was readily detected in tumor metastases. The CD10(high)AGR2(low) phenotype in primary tumors is predictive of poor outcome; however, the CD10(low)AGR2(high) phenotype is more common in metastases. It appears that AGR2 has a protective function in primary tumors but may have a role in the distal spread of tumor cells.

Published
2013

4. Data from Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer

Author

Zhang, Yixian, primary, Castaneda, Stephen, primary, Dumble, Melissa, primary, Wang, Maoliang, primary, Mileski, Mary, primary, Qu, Zhengxing, primary, Kim, Steven, primary, Shi, Victoria, primary, Kraft, Patricia, primary, Gao, Ying, primary, Pak, Jenny, primary, Sapra, Puja, primary, Bandaru, Raj, primary, Zhao, Hong, primary, Vessella, Robert L., primary, Horak, Ivan D., primary, and Greenberger, Lee M., primary

Published
2023
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7. Supplementary Methods, Figures 1-5 from Reduced Expression of the Androgen Receptor by Third Generation of Antisense Shows Antitumor Activity in Models of Prostate Cancer

Author

Zhang, Yixian, primary, Castaneda, Stephen, primary, Dumble, Melissa, primary, Wang, Maoliang, primary, Mileski, Mary, primary, Qu, Zhengxing, primary, Kim, Steven, primary, Shi, Victoria, primary, Kraft, Patricia, primary, Gao, Ying, primary, Pak, Jenny, primary, Sapra, Puja, primary, Bandaru, Raj, primary, Zhao, Hong, primary, Vessella, Robert L., primary, Horak, Ivan D., primary, and Greenberger, Lee M., primary

Published
2023
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8. Supplementary Figure 2 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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9. Supplementary Figure 3 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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12. Supplementary Figure 5 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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13. Supplementary Figure 6 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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14. Supplementary Figure 8 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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15. Supplementary Figure 4 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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16. Supplementary Figure 7 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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17. Supplementary Figure 1 from VEGF/Neuropilin-2 Regulation of Bmi-1 and Consequent Repression of IGF-IR Define a Novel Mechanism of Aggressive Prostate Cancer

Author

Goel, Hira Lal, primary, Chang, Cheng, primary, Pursell, Bryan, primary, Leav, Irwin, primary, Lyle, Stephen, primary, Xi, Hualin Simon, primary, Hsieh, Chung-Cheng, primary, Adisetiyo, Helty, primary, Roy-Burman, Pradip, primary, Coleman, Ilsa M., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, Davis, Roger J., primary, Plymate, Stephen R., primary, and Mercurio, Arthur M., primary

Published
2023
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19. Supplementary Table 5 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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20. Supplementary Table 1 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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21. Supplementary Material from Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts

Author

Lam, Hung-Ming, primary, McMullin, Ryan, primary, Nguyen, Holly M., primary, Coleman, Ilsa, primary, Gormley, Michael, primary, Gulati, Roman, primary, Brown, Lisha G., primary, Holt, Sarah K., primary, Li, Weimin, primary, Ricci, Deborah S., primary, Verstraeten, Karin, primary, Thomas, Shibu, primary, Mostaghel, Elahe A., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Corey, Eva, primary

Published
2023
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22. Data from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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23. Supplementary Table 2 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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24. Supplemental Figure 6 from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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25. Supplementary Table 3 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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26. Supplemental Figure 3 from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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27. Supplementary Table. S2 from GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models

Author

Shourideh, Mojgan, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, DePriest, Adam, primary, Wadosky, Kristine M, primary, Gillard, Bryan M, primary, Karasik, Ellen, primary, Heemers, Hannelore, primary, Kyprianou, Natasha, primary, Gelman, Irwin H., primary, Corey, Eva, primary, Vessella, Robert L, primary, Mohler, James L., primary, and Koochekpour, Shahriar, primary

Published
2023
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28. Supplementary Figure S4 from Cyclin D1 Loss Distinguishes Prostatic Small-Cell Carcinoma from Most Prostatic Adenocarcinomas

Author

Tsai, Harrison, primary, Morais, Carlos L., primary, Alshalalfa, Mohammed, primary, Tan, Hsueh-Li, primary, Haddad, Zaid, primary, Hicks, Jessica, primary, Gupta, Nilesh, primary, Epstein, Jonathan I., primary, Netto, George J., primary, Isaacs, William B., primary, Luo, Jun, primary, Mehra, Rohit, primary, Vessella, Robert L., primary, Karnes, R. Jeffrey, primary, Schaeffer, Edward M., primary, Davicioni, Elai, primary, De Marzo, Angelo M., primary, and Lotan, Tamara L., primary

Published
2023
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29. Supplemental Figure 5 from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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30. Supplementary Figure. S3 from GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models

Author

Shourideh, Mojgan, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, DePriest, Adam, primary, Wadosky, Kristine M, primary, Gillard, Bryan M, primary, Karasik, Ellen, primary, Heemers, Hannelore, primary, Kyprianou, Natasha, primary, Gelman, Irwin H., primary, Corey, Eva, primary, Vessella, Robert L, primary, Mohler, James L., primary, and Koochekpour, Shahriar, primary

Published
2023
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31. Supplemental Table 1-5 from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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32. Supplemental Figure Legends from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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33. Supplementary Figure Legends from GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models

Author

Shourideh, Mojgan, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, DePriest, Adam, primary, Wadosky, Kristine M, primary, Gillard, Bryan M, primary, Karasik, Ellen, primary, Heemers, Hannelore, primary, Kyprianou, Natasha, primary, Gelman, Irwin H., primary, Corey, Eva, primary, Vessella, Robert L, primary, Mohler, James L., primary, and Koochekpour, Shahriar, primary

Published
2023
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34. Supplementary Table 4 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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35. Supplemental Figure 4 from SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

Author

Zhang, Xiaotun, primary, Coleman, Ilsa M., primary, Brown, Lisha G., primary, True, Lawrence D., primary, Kollath, Lori, primary, Lucas, Jared M., primary, Lam, Hung-Ming, primary, Dumpit, Ruth, primary, Corey, Eva, primary, Chéry, Lisly, primary, Lakely, Bryce, primary, Higano, Celestia S., primary, Montgomery, Bruce, primary, Roudier, Martine, primary, Lange, Paul H., primary, Nelson, Peter S., primary, Vessella, Robert L., primary, and Morrissey, Colm, primary

Published
2023
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36. Supplementary Figure 1 from HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

Author

Laitinen, Virpi H., primary, Wahlfors, Tiina, primary, Saaristo, Leena, primary, Rantapero, Tommi, primary, Pelttari, Liisa M., primary, Kilpivaara, Outi, primary, Laasanen, Satu-Leena, primary, Kallioniemi, Anne, primary, Nevanlinna, Heli, primary, Aaltonen, Lauri, primary, Vessella, Robert L., primary, Auvinen, Anssi, primary, Visakorpi, Tapio, primary, Tammela, Teuvo L.J., primary, and Schleutker, Johanna, primary

Published
2023
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37. Supplementary Figure S1 and Supplementary Tables S1-2 from Radium-223 Inhibits Osseous Prostate Cancer Growth by Dual Targeting of Cancer Cells and Bone Microenvironment in Mouse Models

Author

Suominen, Mari I., primary, Fagerlund, Katja M., primary, Rissanen, Jukka P., primary, Konkol, Yvonne M., primary, Morko, Jukka P., primary, Peng, ZhiQi, primary, Alhoniemi, Esa J., primary, Laine, Salla K., primary, Corey, Eva, primary, Mumberg, Dominik, primary, Ziegelbauer, Karl, primary, Käkönen, Sanna-Maria, primary, Halleen, Jussi M., primary, Vessella, Robert L., primary, and Scholz, Arne, primary

Published
2023
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38. Supplementary Materials and Methods from GRM1 is An Androgen-Regulated Gene and its Expression Correlates with Prostate Cancer Progression in Pre-Clinical Models

Author

Shourideh, Mojgan, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, DePriest, Adam, primary, Wadosky, Kristine M, primary, Gillard, Bryan M, primary, Karasik, Ellen, primary, Heemers, Hannelore, primary, Kyprianou, Natasha, primary, Gelman, Irwin H., primary, Corey, Eva, primary, Vessella, Robert L, primary, Mohler, James L., primary, and Koochekpour, Shahriar, primary

Published
2023
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39. Supplementary Figure 5 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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41. Supplementary Figure 4 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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42. Data from Cyclin D1 Loss Distinguishes Prostatic Small-Cell Carcinoma from Most Prostatic Adenocarcinomas

Author

Tsai, Harrison, primary, Morais, Carlos L., primary, Alshalalfa, Mohammed, primary, Tan, Hsueh-Li, primary, Haddad, Zaid, primary, Hicks, Jessica, primary, Gupta, Nilesh, primary, Epstein, Jonathan I., primary, Netto, George J., primary, Isaacs, William B., primary, Luo, Jun, primary, Mehra, Rohit, primary, Vessella, Robert L., primary, Karnes, R. Jeffrey, primary, Schaeffer, Edward M., primary, Davicioni, Elai, primary, De Marzo, Angelo M., primary, and Lotan, Tamara L., primary

Published
2023
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43. Supplementary Figure Legend from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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44. Supplementary Figure 3 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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45. Supplementary Figure 2 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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46. supplemental figure legend and Materials and Methods from Cyclin D1 Loss Distinguishes Prostatic Small-Cell Carcinoma from Most Prostatic Adenocarcinomas

Author

Tsai, Harrison, primary, Morais, Carlos L., primary, Alshalalfa, Mohammed, primary, Tan, Hsueh-Li, primary, Haddad, Zaid, primary, Hicks, Jessica, primary, Gupta, Nilesh, primary, Epstein, Jonathan I., primary, Netto, George J., primary, Isaacs, William B., primary, Luo, Jun, primary, Mehra, Rohit, primary, Vessella, Robert L., primary, Karnes, R. Jeffrey, primary, Schaeffer, Edward M., primary, Davicioni, Elai, primary, De Marzo, Angelo M., primary, and Lotan, Tamara L., primary

Published
2023
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47. Supplementary Table 2 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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48. Supplementary Figure 1 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
Full Text
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49. Supplementary Table 1 from Serum Glutamate Levels Correlate with Gleason Score and Glutamate Blockade Decreases Proliferation, Migration, and Invasion and Induces Apoptosis in Prostate Cancer Cells

Author

Koochekpour, Shahriar, primary, Majumdar, Sunipa, primary, Azabdaftari, Gissou, primary, Attwood, Kristopher, primary, Scioneaux, Ray, primary, Subramani, Dhatchayini, primary, Manhardt, Charles, primary, Lorusso, Giovanni D., primary, Willard, Stacey S., primary, Thompson, Hillary, primary, Shourideh, Mojgan, primary, Rezaei, Katayoon, primary, Sartor, Oliver, primary, Mohler, James L., primary, and Vessella, Robert L., primary

Published
2023
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50. Data from Genomic Alterations Indicate Tumor Origin and Varied Metastatic Potential of Disseminated Cells from Prostate Cancer Patients

Author

Holcomb, Ilona N., primary, Grove, Douglas I., primary, Kinnunen, Martin, primary, Friedman, Cynthia L., primary, Gallaher, Ian S., primary, Morgan, Todd M., primary, Sather, Cassandra L., primary, Delrow, Jeffrey J., primary, Nelson, Peter S., primary, Lange, Paul H., primary, Ellis, William J., primary, True, Lawrence D., primary, Young, Janet M., primary, Hsu, Li, primary, Trask, Barbara J., primary, and Vessella, Robert L., primary

Published
2023
Full Text
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