Search

Seven patients with active distal ulcerative colitis were treated with IgG enemas given as a daily bedtime retention enema for two weeks. Evaluation of effect was assessed by means of sigmoidoscopy with biopsy, measuring acute phase reactants in peripheral blood, and measuring the faecal protein loss. Clinical signs of active disease were registered by the patients on a diary chart. Five patients completed the treatment period, two patients were withdrawn after 7 and 10 days due to deterioration of disease. Four patients did not register any effect, whereas one patient improved clinically. In conclusion, rectally administered IgG did not exert any effect on rectal ulcerative colitis in our study.

The possibility of using molten mixtures of 1,4-dimethyl-1,2,4-triazolium chloride (DMTC) and aluminum chloride (AlCl3) as secondary battery electrolytes was studied, in some cases extended by the copresence of sodium chloride. DMTC-AlCl, mixtures demonstrated high specific conductivity in a wide temperature range. The equimolar system is most conductive and has kappa values between 4.02 x 10(-5) and 7.78 x 10(-2) S cm-1 in the range from -31 to 123-degrees-C, respectively. The electrochemical window of DMTC-containing sodium tetrachloroaluminate melts varied in the region of 2.5 to 2.2 V (150-170-degrees-C) depending on melt acidity and anode material. DMTC, being specifically adsorbed and reduced on the tungsten electrode surface, had an inhibiting effect on the aluminum reduction, but this effect was suppressed on the aluminum substrate. An electrochemical process with high current density (tens of milliamperes per square centimeter) was observed at 0.344 V on the acidic sodium tetrachloroaluminate background, involving a free triazolium radical mechanism. Molten DMTC-AlCl3 electrolytes are acceptable for battery performance and both the aluminum anode and the triazolium electrolyte can be used as active materials in the acidic DMTC-AlCl3 mixtures.

The preparation of several triazolium chloride derivates has been performed. This includes 1-ethyl-4-methyl-1,2,4-triazolium chloride 1,4- dimethyl-1,24-triazolium chloride 1,2-dimethyl-1,2,3-triazolium chloride 1- methyl-3-paramethoxy-benzyl-1,2,3-triazolium chloride.

This final report for the project 'Organic Electrolytes for Sodium Batteries' contains a summary of earlier given status reports in connection with the project. The aim of the investigations was to develop new room temperature molten salts electrolytes mainly with radical substituted heterocyclic organic chlorides mixed with aluminum chloride. The new electrolytes should have an ionic conductivity comparable with MEIC1:AlCl3 or better. A computer model program MOPAC (Molecular Orbital Package) was to be included to calculate theoretically reduction potentials for a variety of organic cations. Furthermore, MOPAC could be utilized to predict the electron densities, and then give a prediction of the stability of the organic cation.

Udgivelsesdato: 1990-May, We report a detailed study on oral lesions and their association with the WHO revised provisional case definition of AIDS as well as serologic signs of HIV infection among 186 patients in Dar Es Salaam, Tanzania. The patient material consisted of 39 hospitalized suspected AIDS patients, 44 medical nonsuspected patients, 53 dental outpatients, and 50 patients with sexually transmitted diseases. The male:female ratio was 2.1:1 on average. Oral examination was done without knowledge of the HIV status of the patients. Among 39 suspected AIDS patients 97% had WHO AIDS criteria and 90% were seropositive for HIV. Among the 147 patients not suspected of having AIDS 18 (12%) had AIDS criteria and 15% had serologic evidence of HIV infection. The presence of WHO AIDS criteria correlated significantly with the presence of HIV antibodies, but not with HIV antigen. Oral lesions were found in 54% of those with AIDS criteria and 52% of HIV-infected patients, as compared to 3% and 6% of the patients without AIDS criteria and HIV infection, respectively (p less than 0.01). Among patients with AIDS atrophic candidiasis occurred in 21%, pseudomembranous candidiasis in 23%, hairy leukoplakia in 36%, herpetic stomatitis in 2%, Kaposi's sarcoma in 4%, and nonspecific ulcer in 4%. The presence of oral lesions had a high predictive value for presence of AIDS criteria as well as for presence of HIV infection in this hospital setting. All patients should have a thorough oral examination and the presence of the aforementioned oral lesions should lead to testing for HIV infection.