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1. The clinical spectrum of COVID-19–associated cutaneous manifestations: An Italian multicenter study of 200 adult patients

Author

Marzano, Angelo Valerio, Genovese, Giovanni, Moltrasio, Chiara, Gaspari, Valeria, Vezzoli, Pamela, Maione, Vincenzo, Misciali, Cosimo, Sena, Paolo, Patrizi, Annalisa, Offidani, Annamaria, Quaglino, Pietro, Arco, Renato, Caproni, Marzia, Rovesti, Miriam, Bordin, Giorgio, Recalcati, Sebastiano, Potenza, Concetta, Guarneri, Claudio, Fabbrocini, Gabriella, Tomasini, Carlo, Sorci, Mariarita, Lombardo, Maurizio, Gisondi, Paolo, Conti, Andrea, Casazza, Giovanni, Peris, Ketty, Calzavara-Pinton, Piergiacomo, and Berti, Emilio

Published
2021
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4. Autoimmune bullous dermatoses in cancer patients treated by immunotherapy: a literature review and Italian multicentric experience

Author

Merli, Martina, primary, Accorinti, Martina, additional, Romagnuolo, Maurizio, additional, Marzano, Angelo, additional, Di Zenzo, Giovanni, additional, Moro, Francesco, additional, Antiga, Emiliano, additional, Maglie, Roberto, additional, Cozzani, Emanuele, additional, Parodi, Aurora, additional, Gasparini, Giulia, additional, Sollena, Pietro, additional, De Simone, Clara, additional, Caproni, Marzia, additional, Pisano, Luigi, additional, Fattore, Davide, additional, Balestri, Riccardo, additional, Sena, Paolo, additional, Vezzoli, Pamela, additional, Teoli, Miriam, additional, Ardigò, Marco, additional, Vassallo, Camilla, additional, Michelerio, Andrea, additional, Satta, Rosanna Rita, additional, Dika, Emi, additional, Melotti, Barbara, additional, Ribero, Simone, additional, and Quaglino, Pietro, additional

Published
2023
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5. Clinical‐epidemiological aspects of the Monkeypox 2022 epidemic: A multicentre study by the Italian SIDeMaST Group of Sexually Transmitted, Infectious and Tropical Diseases

Author

Carugno, Andrea, primary, Parietti, Michele, additional, Ciccarese, Giulia, additional, Campanati, Anna, additional, Diotallevi, Federico, additional, Atzori, Laura, additional, Balestri, Riccardo, additional, Caccavale, Stefano, additional, Bellinato, Francesco, additional, Benatti, Simone Vasilij, additional, Venturelli, Serena, additional, Vezzoli, Pamela, additional, Sena, Paolo, additional, and Papini, Manuela, additional

Published
2023
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6. Impact of COVID‐19 in patients with autoimmune bullous diseases: Report from an international registry

Author

Meijer, Joost M., primary, Rashid, Hanan, additional, Vergadi, Styliani, additional, Antiga, Emiliano, additional, Vezzoli, Pamela, additional, Balestri, Riccardo, additional, Patsatsi, Aikaterini, additional, Uzun, Soner, additional, Skiljevic, Dusan, additional, Jedlickova, Hana, additional, Janickova, Lucia, additional, Corrà, Alberto, additional, Ponziani, Alessandra, additional, Günther, Claudia, additional, Cianchini, Giuseppe, additional, Schefzyk, Matthias, additional, Marzano, Angelo, additional, Di Zenzo, Giovanni, additional, Shimanovich, Iakov, additional, Fairley, Janet, additional, Mascaró, Jose M., additional, Caproni, Marzia, additional, Maglie, Roberto, additional, Schmidt, Enno, additional, and Horváth, Barbara, additional

Published
2023
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7. Metronidazole-induced linear immunoglobulin A disease in a patient suffering from ulcerative colitis: a case report and focused review of the literature.

Author

Buffon, Stefano, Parietti, Michele, Carugno, Andrea, Test, Elisa Robustelli, Marzano, Angelo Valerio, Sena, Paolo, and Vezzoli, Pamela

Subjects
DRUG side effects, ORAL drug administration, ULCERATIVE colitis, BLISTERS, IDIOPATHIC diseases
Abstract

Linear immunoglobulin (Ig) A disease (LAD) is a rare autoimmune blistering dermatosis caused by linear deposition of IgA1 along the dermoepidermal junction of skin and mucosae. It can affect both children and adults. Although idiopathic in most cases, it can also be associated with infections, malignancies, or drug administration. Among medications, antibiotics are most commonly responsible, particularly vancomycin. We report the case of a 51-year-old female patient who developed mucocutaneous LAD after oral metronidazole administration, which was confirmed by histopathological examination and direct immunofluorescence of one of the bullous lesions. Lesions rapidly cleared after metronidazole discontinuation and a short course of oral methylprednisolone and dapsone. To our knowledge, this is the third reported case of metronidazole-induced LAD and the first in which metronidazole was not administered in combination with other antibiotics such as ceftriaxone [ABSTRACT FROM AUTHOR]

Published
2024
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8. Safety of anti-IL-23 risankizumab treatment in a patient with severe psoriasis and Charcot-Marie-Tooth disease

Author

Carugno, A, Brigenti, N, Gisondi, P, Al Ghadban, Z, Parietti, M, Vezzoli, P, Sena, P, Pisciotta, C, Carugno, Andrea, Brigenti, Noemi, Gisondi, Paolo, Al Ghadban, Zeina, Parietti, Michele, Vezzoli, Pamela, Sena, Paolo, Pisciotta, Chiara, Carugno, A, Brigenti, N, Gisondi, P, Al Ghadban, Z, Parietti, M, Vezzoli, P, Sena, P, Pisciotta, C, Carugno, Andrea, Brigenti, Noemi, Gisondi, Paolo, Al Ghadban, Zeina, Parietti, Michele, Vezzoli, Pamela, Sena, Paolo, and Pisciotta, Chiara

Published
2023

9. Metronidazole-induced linear immunoglobulin A disease in a patient suffering from ulcerative colitis: a case report and focused review of the literature

Author

Buffon, S, Parietti, M, Carugno, A, Robustelli Test, E, Marzano, A, Sena, P, Vezzoli, P, Buffon, Stefano, Parietti, Michele, Carugno, Andrea, Robustelli Test, Elisa, Marzano, Angelo Valerio, Sena, Paolo, Vezzoli, Pamela, Buffon, S, Parietti, M, Carugno, A, Robustelli Test, E, Marzano, A, Sena, P, Vezzoli, P, Buffon, Stefano, Parietti, Michele, Carugno, Andrea, Robustelli Test, Elisa, Marzano, Angelo Valerio, Sena, Paolo, and Vezzoli, Pamela

Abstract

Linear immunoglobulin (Ig) A disease (LAD) is a rare autoimmune blistering dermatosis caused by linear deposition of IgA1 along the dermoepidermal junction of skin and mucosae. It can affect both children and adults. Although idiopathic in most cases, it can also be associated with infections, malignancies, or drug administration. Among medications, antibiotics are most commonly responsible, particularly vancomycin. We report the case of a 51-year-old female patient who developed mucocutaneous LAD after oral metronidazole administration, which was confirmed by histopathological examination and direct immunofluorescence of one of the bullous lesions. Lesions rapidly cleared after metronidazole discontinuation and a short course of oral methylprednisolone and dapsone. To our knowledge, this is the third reported case of metronidazole-induced LAD, and the first in which metronidazole was not administered in combination with other antibiotics such as ceftriaxone.

Published
2023

10. SARS-CoV-2 Detection by Digital Polymerase Chain Reaction and Immunohistochemistry in Skin Biopsies from 52 Patients with Different COVID-19-Associated Cutaneous Phenotypes

Author

Marzano, Angelo V., primary, Moltrasio, Chiara, additional, Genovese, Giovanni, additional, De Andrea, Marco, additional, Caneparo, Valeria, additional, Vezzoli, Pamela, additional, Morotti, Denise, additional, Sena, Paolo, additional, Venturini, Marina, additional, Battocchio, Simonetta, additional, Caputo, Valentina, additional, Rizzo, Nathalie, additional, Maronese, Carlo Alberto, additional, Venegoni, Luigia, additional, Boggio, Francesca Laura, additional, Rongioletti, Franco, additional, Calzavara-Pinton, Piergiacomo, additional, and Berti, Emilio, additional

Published
2023
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13. Bullous Pemphigoid Associated With COVID-19 Vaccines: An Italian Multicentre Study

Author

Maronese, Carlo Alberto, primary, Caproni, Marzia, additional, Moltrasio, Chiara, additional, Genovese, Giovanni, additional, Vezzoli, Pamela, additional, Sena, Paolo, additional, Previtali, Giulia, additional, Cozzani, Emanuele, additional, Gasparini, Giulia, additional, Parodi, Aurora, additional, Atzori, Laura, additional, Antiga, Emiliano, additional, Maglie, Roberto, additional, Moro, Francesco, additional, Mariotti, Elena Biancamaria, additional, Corrà, Alberto, additional, Pallotta, Sabatino, additional, Didona, Biagio, additional, Marzano, Angelo Valerio, additional, and Di Zenzo, Giovanni, additional

Published
2022
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15. RNAscope in situ hybridization and RT‐PCR for detection of SARS‐CoV‐2 in chilblain‐like lesions: A clinical, laboratory and histopathological study

Author

Robustelli Test, Elisa, primary, Sena, Paolo, additional, Locatelli, Andrea Gustavo, additional, Carugno, Andrea, additional, Mercurio, Marco, additional, Moggio, Erica, additional, Gambini, Daniele Mario, additional, Arosio, Marco Enrico Giovanni, additional, Callegaro, Annapaola, additional, Morotti, Denise, additional, Gianatti, Andrea, additional, and Vezzoli, Pamela, additional

Published
2022
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27. Skin involvement in cutaneous and systemic vasculitis

Author

Vezzoli Pamela, Marzano Angelo, Berti Emilio, Marzano, A, Vezzoli, P, and Berti, E

Subjects
medicine.medical_specialty, Pathology, business.industry, Polyarteritis nodosa, Systemic Vasculitis, Immunology, Connective tissue, medicine.disease, Dermatology, Connective tissue disease, Purpura, medicine.anatomical_structure, medicine, Humans, Immunology and Allergy, medicine.symptom, Urticarial vasculitis, business, Vasculitis, Cutaneous small-vessel vasculitis, Skin, Human, Systemic vasculitis
Abstract

Cutaneous vasculitides are a heterogeneous group of inflammatory disorders affecting skin blood vessels. They may be triggered by several factors, such as infection or drug, or may be related to underlying disease, notably connective tissue or malignancies. However, vasculitis occurs without any demonstrable triggering agents in a relevant number of patients. On the other hand, vasculitic skin lesions may manifest as a component of vasculitis affecting also internal organs; in someone of these patients, skin involvement occurs initially as the sole sign of disease, leading to consider cutaneous vasculitis a diagnosis of exclusion. In this review, we have focused on the most common variants of cutaneous vasculitis, including cutaneous small vessel vasculitis and urticarial vasculitis as well as Henoch-Schönlein purpura, a systemic form in which however skin involvement often predominates. We have also argued on livedoid vasculopathy, a cutaneous entity which, although nonfrankly vasculitic in origin, is frequently associated with connective tissue disease. Finally, we have analyzed the variety of cutaneous manifestations that may develop during the course of the main systemic vasculitides, such as Wegener's granulomatosis, Churg-Strauss syndrome and polyarteritis nodosa.

Published
2013
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32. Blastic Plasmacytoid Dendritic Cell Neoplasm: Clinical, Immunohistochemical and Molecular Evaluation of 23 Cases with Primary Cutaneous Involvement,

Author

Berti, Emilio, primary, Lucioni, Marco, additional, Onida, Francesco, additional, Novara, Francesca, additional, Caprini, Elisabetta, additional, Fiandrino, Giacomo, additional, Riboni, Roberta, additional, Fanoni, Daniele, additional, Vezzoli, Pamela, additional, Arra, Mariarosa, additional, Venegoni, Luigia, additional, Nicola, Marta, additional, Dallera, Elena, additional, Arcaini, Luca, additional, Saporiti, Giorgia, additional, Travaglino, Erica, additional, Boveri, Emanuela, additional, Zuffardi, Orsetta, additional, Russo, Giandomenico, additional, and Paulli, Marco, additional

Published
2011
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38. Three cases of primary cutaneous lymphoblastic lymphoma: microarray-based comparative genomic hybridization and gene expression profiling studies with review of literature.

Author

Vezzoli, Pamela, Novara, Francesca, Fanoni, Daniele, Gambini, Daniele, Balice, Ylenia, Venegoni, Luigia, Paulli, Marco, Crosti, Carlo, and Berti, Emilio

Subjects
*LYMPHOMAS, *COMPARATIVE genomic hybridization, *DNA microarrays, *GENOMICS, *TRISOMY, *GENE expression profiling, *CHROMOSOME abnormalities
Abstract

Lymphoblastic lymphoma (LBL) is a neoplasm of precursor B- or T-lymphocytes, and primary skin involvement is uncommon. The aim of the study was to review all reported primary cutaneous (PC)-LBLs and to examine three new cases to better characterize this neoplasm. Two of our patients showed a pre-B phenotype (PC-B-LBL) and one a never-reported pre-T phenotype (PC-T-LBL). The patient with PC-T-LBL showed an aggressive course, while those with PC-B-LBL showed a complete remission (CR) after polychemotherapy. Cytogenetic analysis and gene expression profiling (GEP) were performed on one case of PC-B-LBL and on that of PC-T-LBL. A specimen of PC-B-LBL and two specimens (early and late stage) of PC-T-LBL were investigated by microarray-based comparative genomic hybridization (CGH). All specimens revealed trisomy of chromosome 4. PC-T-LBL showed a gain of 1p36.33-p22.1 in the early stage and multiple chromosome gains/losses in the late stage. Our data suggest that trisomy 4 could be detected early in LBL and gain of 1p36.33-p22.1 could be an interesting marker in PC-T-LBL. LBL is an aggressive disease but, only in B-LBL, the cutaneous presentation seems to be a favorable prognostic factor and polychemotherapy is the best therapeutic approach. We suggest that PC-LBL should be included as a provisional clinicopathologic entity in future cutaneous lymphoma classification. [ABSTRACT FROM AUTHOR]

Published
2012
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39. Cetuximab-induced Acneiform Eruption and the Response to Isotretinoin.

Author

Vezzoli, Pamela, Marzano, Angelo Valerio, Onida, Francesco, Alessp, Elvio, Galassi, Barbara, Tomirotti, Maurizio, and Berti, Emillo

Subjects
*LETTERS to the editor, *EPIDERMAL growth factor
Abstract

A letter to the editor is presented in response to the article on epidermal growth factor receptor, published in the previous issue.

Published
2008
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41. Multidisciplinary and personalized approach to the management of mycosis fungoides with chlormethine gel: a collection of clinical experiences.

Author

Violetti SA, Ardigò M, Fava P, Gritti G, Morsia E, Onida F, Paulli M, Pileri A, Quaglino P, Rupoli S, Teoli M, and Vezzoli P

Abstract

Topical chlormethine (CL) gel formulation was approved by the EMA in 2017 for the treatment of adult patients with mycosis fungoides (MF). To expand the knowledge on the management of MF, this paper provides an overview of clinical practice evidence about the MF diagnostic phase and a collection of clinical experiences to better characterize the use of CL gel in daily practice. Collected cases underline the importance of the concomitant biopsy and clinical evaluation in the diagnostic phase, with the contribution of a multidisciplinary team, and support the use of CL gel as a first-line or adjuvant treatment in selected patients., Competing Interests: Disclosure and potential conflicts of interest: SAV has received speaking honoraria and advisory board fees from Takeda, Kyowa Kirin and Recordati and advisory board fees from Recordati. FO has received speaking honoraria from Takeda, Medac, Kyowa Kirin, Menarini-Stemline and Recordati, advisory board fees from Rercordati, and travel support from Medac, Jazz and Janssen. GG reports consultancy fees from Genmab, Roche, Abbvie, Ideogen, Kite-Gilead and Takeda, and travel support from Gilead Kite, Janssen and Beigene. PQ received advisory board and speaker fees from Kyowa Kirin, Takeda, Helsinn, Recordati, Cellgene, Innate Pharma and Therakos. MA has received speaking honoraria and advisory board fees from Takeda, Pierre Fabre, Kyowa Kirin, Helsinn, Recordati, Almirall and Cantabria. AP has received consulting and advisory board fees from Kyowa Kyrin, Menarini Stemline and Recordati. SR has received speaking honoraria from Takeda, Kyowa Kirin and Recordati. MT has received support and advisory board fees from Kyowa Kirin, Boehringer Ingelheim and Recordati. MP has received invited speaker/advisory board feed from Menarini, Kyowa Kirin and Recordati. All other authors declare no conflict of interest. The International Committee of Medical Journal Editors (ICMJE) Potential Conflicts of Interests form for the authors is available for download at: https://www.drugsincontext.com/wp-content/uploads/2024/09/dic.2024-6-1-COI.pdf, (Copyright © 2024 Alberti Violetti S, Ardigò M, Fava P, Gritti G, Morsia E, Onida F, Paulli M, Pileri A, Quaglino P, Rupoli S, Teoli M, Vezzoli P.)

Published
2024
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