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363 results on '"Vienken J"'

26. Erythrocytes and Lymphocytes as Drug Carrier Systems: Techniques for Entrapment of Drugs in Living Cells

Author

Zimmermann, U., Pilwat, G., Vienken, J., Allfrey, V. G., editor, Allgöwer, M., editor, Berenblum, I., editor, Bergel, F., editor, Bernard, J., editor, Bernhard, W., editor, Blokhin, N. N., editor, Bock, H. E., editor, Braun, W., editor, Bucalossi, P., editor, Chaklin, A. V., editor, Chorazy, M., editor, Cunningham, G. J., editor, Della Porta, G., editor, Denoix, P., editor, Dulbecco, R., editor, Eagle, H., editor, Eker, R., editor, Good, R. A., editor, Grabar, P., editor, Harris, R. J. C., editor, Hecker, E., editor, Herbeuval, R., editor, Higginson, J., editor, Hueper, W. C., editor, Isliker, H., editor, Kieler, J., editor, Kirsten, W. H., editor, Klein, G., editor, Koprowski, H., editor, Koss, L. G., editor, Macbeth, R. A., editor, Martz, G., editor, Mathé, G., editor, Mühlbock, O., editor, Old, L. J., editor, Potter, V. R., editor, Sabin, A. B., editor, Sachs, L., editor, Saxén, E. A., editor, Schmidt, C. G., editor, Spiegelman, S., editor, Szybalski, W., editor, Tagnon, H., editor, Tissières, A., editor, Uehlinger, E., editor, Wissler, R. W., editor, Rentchnick, P., editor, Senn, H. J., editor, Mathé, Georges, editor, and Muggia, Franco M., editor

Published
1980
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31. Side Effects of Hybrid Liver Support Therapy: TNF-α Liberation in Pigs, Associated with Extracorporeal Bioreactors

Author

Jörg C. Gerlach, Trost O, Jörres A, James M. Courtney, Peter Neuhaus, Hole O, Gerhard Gahl, and Vienken J

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, 030232 urology & nephrology, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, General Medicine, 030204 cardiovascular system & hematology, Liver transplantation, Extracorporeal, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, Immune system, Endocrinology, Internal medicine, Immunology, Homologous chromosome, Medicine, Liberation, Tumor necrosis factor alpha, Cell activation, business, Perfusion
Abstract

During acute liver failure, hybrid liver support therapy could serve as a bridge to liver transplantation. In this desired temporary use, immune competent cell responses, such as the production of cytokines, might be of limiting relevance. We have investigated the Tumor Necrosis Factor-α (TNF) liberation in two models using pigs, connected with an extracorporeal bioreactor with homologous hepatocytes: TNF liberation was measured in arterial plasma during a 4 day perfusion time in untreated animals, model (i), and during short term perfusion of hepatectomized pigs in model (ii). Animals four days after catheter implantation in model (i) had TNF values of < 5 pg/ml. After connecting the system without hepatocytes, TNF rose to 9.7 ± 2 within 120 min and rose further to 32.6 ± 6 pg/ml within 4 hours after filling the system with the homologous hepatocytes. After 24 hours of continuous perfusion and during four days of perfusion, the TNF levels were lowered to baseline levels. In model (ii), TNF rose to 220 ± 130 pg/ml within 180 min and decreased to 110 ± 10 pg/ml within six hours, whereas controls without hepatocytes showed mean levels with a maximum of 120 ± 20 pg/ml. In both models, there was no correlation between TNF levels and clinical abnormalities such as fever or shock symptoms. There is evidence for an activation of blood cells during experimental extracorporeal hybrid support. No typical side effects were, however, observed. Thus, TNF mediated extracorporeal cell activation does not appear to limit the application of homologous hybrid liver support therapy.

Published
1993
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34. In vitro bicarbonate and urea kinetics during hemodialysis and online hemodiafiltration

Author

Morel, H., Jaffrin, M.Y., Legallais, C., Vienken, J., Guilbert, Chantal, Biomécanique et Bioingénierie (BMBI), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), Fresenius Medical Care AG and Co, and Fresenius

Subjects
ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2008

35. Computer Aided Time-Lapse Video Analysis of Hepatocyte Morphology during Adhesion to Cellulose Membranes

Author

Jörg C. Gerlach, Vienken J, Klaus Affeld, and P. Walker

Subjects
biology, 030232 urology & nephrology, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Video microscopy, General Medicine, Adhesion, 030204 cardiovascular system & hematology, Cell morphology, Cell biology, Biomaterials, Fibronectin, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine.anatomical_structure, Membrane, chemistry, Hepatocyte, medicine, Biophysics, biology.protein, Cellulose, Cell adhesion
Abstract

An investigation was performed to demonstrate that time-lapse cinematography and computer aided video analysis of cell morphology is suitable to study and compare the characteristics of hepatocytes during the adhesion process to membranes. We chose to compare ordinary cellulose Cuprophan membranes and membranes coated with collagen or fibronectin. Striking differences between uncoated cellulose and fibronectin or collagen coating were seen in the cell count per square millimeter and adhesion behaviour. On the investigated uncoated Cuprophan the hepatocytes were found to attach but not to spread whilst on collagen coated Cuprophan most of the cells spread spherically, and on fibronectin coated membranes most of the cells flattened spherically or polygonally. Time-lapse video microscopy seems to be a valuable technique for assessing the morphologic behaviour of cells in a detailed and quantitative manner in order to improve the hepatocyte culture technique in bioreactors for hybrid systems.

Published
1990
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42. Biocompatibility: is it a relevant consideration for today's haemodialysis?

Author

Vienken J and Shaldon S

Subjects
Anaphylatoxins, Biocompatibility, 030232 urology & nephrology, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Biocompatible Materials, 030204 cardiovascular system & hematology, Biomaterials, 03 medical and health sciences, 0302 clinical medicine, Renal Dialysis, Equipment Reuse, Medicine, Humans, Hypoxia, Complement Activation, business.industry, Proteins, Membranes, Artificial, General Medicine, Amyloidosis, Leukopenia, Endotoxins, Kidney Failure, Chronic, Engineering ethics, business, Biomedical engineering
Published
1996

43. Ultra long-term sodium balance studies during the Mars500 campaign

Author

Rakova, N, primary, Jüttner, K, additional, Rauh, M, additional, Dahlmann, A, additional, Goller, U, additional, Beck, L, additional, Agureev, A, additional, Vassilieva, G, additional, Lenkova, L, additional, Johannes, B, additional, Wabel, P, additional, Moissl, U, additional, Vienken, J, additional, Gerzer, R, additional, Eckardt, KU, additional, Müller, DN, additional, Kirsch, K, additional, Morukov, B, additional, Luft, FC, additional, and Titze, J, additional

Published
2012
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44. Nutrition, inflammation and oxidative stress - CKD 5D

Author

Usvyat, L. A., primary, Raimann, J., additional, Thijssen, S., additional, van der Sande, F. M., additional, Kooman, J., additional, Levin, N. W., additional, Kotanko, P., additional, Von Gersdorff, G., additional, Schaller, M., additional, Bayh, I., additional, Etter, M., additional, Grassmann, A., additional, Guinsburg, A., additional, Lam, M., additional, Marcelli, D., additional, Marelli, C., additional, Scatizzi, L., additional, Tashman, A., additional, Toffelmire, T., additional, Usvyat, L., additional, Van der Sande, F., additional, Wang, Y., additional, Barth, C., additional, Moffitt, T., additional, Hariton, F., additional, Devlin, M., additional, Garrett, P., additional, Hannon-Fletcher, M., additional, Ekramzadeh, M., additional, Sohrabi, Z., additional, Salehi, M., additional, Fallahzadeh, M. K., additional, Ayatollahi, M., additional, Geramizadeh, B., additional, Hassanzadeh, J., additional, Sagheb, M. M., additional, Beberashvili, I., additional, Sinuani, I., additional, Azar, A., additional, Kadoshi, H., additional, Shapiro, G., additional, Feldman, L., additional, Averbukh, Z., additional, Weissgarten, J., additional, Abe, Y., additional, Watanabe, M., additional, Ito, K., additional, Sasatomi, Y., additional, Ogahara, S., additional, Nakashima, H., additional, Saito, T., additional, Witt, S., additional, Kunze, R., additional, Guth, H. J., additional, Skarabis, H., additional, Vienken, J., additional, Nowak, P., additional, Wilk, R., additional, Mamelka, B., additional, Prymont-Przyminska, A., additional, Zwolinska, A., additional, Sarniak, A., additional, Wlodarczyk, A., additional, Rysz, J., additional, Nowak, D., additional, Trajceska, L., additional, Dzekova-Vidimliski, P., additional, Gelev, S., additional, Arsov, S., additional, Sikole, A., additional, Sonikian, M., additional, Dona, A., additional, Skarakis, I., additional, Metaxaki, P., additional, Chiotis, C., additional, Papoutsis, I., additional, Karaitianou, A., additional, Spiliopoulou, C., additional, Van der Sande, F. M., additional, Usvyat, L. A., additional, Teta, D., additional, Tappy, L., additional, Theumann, N., additional, Halabi, G., additional, Gauthier, T., additional, Mathieu, C., additional, Tremblay, S., additional, Coti, P., additional, Burnier, M., additional, Zanchi, A., additional, Martinez Vea, A., additional, Cabre, C., additional, Villa, D., additional, Munoz, M., additional, Vives, J. P., additional, Arruche, M., additional, Soler, J., additional, Compte, M. T., additional, Aguilera, J., additional, Romeu, M., additional, Giralt, M., additional, Barril, G., additional, Anaya, S., additional, Vozmediano, C., additional, Celayeta, A., additional, Novillo, R., additional, Bernal, V., additional, Beiret, I., additional, Huarte, E., additional, Martin, J., additional, Santana, H., additional, Torres, G., additional, Sousa, F., additional, Sanchez, R., additional, Lopez-Montes, A., additional, Tornero, F., additional, Uson, J., additional, Pousa, M., additional, Giorgi, M., additional, Rdez Cubillo, B., additional, Malhotra, R., additional, Abbas, S. R., additional, Thjissen, S., additional, Carter, M., additional, von Gersdorff, G., additional, Levin, N., additional, Jens, R., additional, Tepel, M., additional, Katharina, E., additional, Andrea, H., additional, Simone, F., additional, Florian, S., additional, Slusanschi, O., additional, Garneata, L., additional, Moraru, R., additional, Preoteasa, E., additional, Barbulescu, C., additional, Santimbrean, C., additional, Klein, C., additional, Dragomir, D., additional, Mircescu, G., additional, Idorn, T., additional, Knop, F., additional, Holst, J. J., additional, Hornum, M., additional, Feldt-Rasmussen, B., additional, Son, Y. K., additional, An, W. S., additional, Kim, S. E., additional, Kim, K. H., additional, Borrelli, S., additional, Minutolo, R., additional, De Nicola, L., additional, Conte, G., additional, De Simone, W., additional, Zito, B., additional, Guastaferro, P., additional, Nigro, F., additional, Bassi, A., additional, Leone, L., additional, Credendino, O., additional, Genualdo, R., additional, Capuano, M., additional, Iulianiello, G., additional, Auricchio, M. R., additional, Sezer, S., additional, Bal, Z., additional, Tutal, E., additional, Erkmen Uyar, M., additional, Ozdemir Acar, F. N., additional, Ribeiro, S., additional, Faria, M. S., additional, Melo, F., additional, Sereno, J., additional, Freitas, I., additional, Mendonca, M., additional, Nascimento, H., additional, Fernandes, J., additional, Rocha-Pereira, P., additional, Miranda, V., additional, Mendonca, D., additional, Quintanilha, A., additional, Belo, L., additional, Costa, E., additional, Reis, F., additional, Santos-Silva, A., additional, Valtuille, R., additional, Casos, M. E., additional, and Fernandez, E. A., additional

Published
2012
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45. Peritoneal dialysis

Author

Kunze, R., primary, Witt, S., additional, Vienken, J., additional, Rie, K., additional, Masayoshi, N., additional, Aritoshi, K., additional, Yoshinaga, O., additional, Yukiko, H., additional, Takahiro, K., additional, Hiroshi, N., additional, Takeshi, N., additional, Aoki, S., additional, Makino, J., additional, Noguchi, M., additional, Yamasaki, F., additional, Toda, S., additional, Santiago, J., additional, Caparros, G., additional, Vozmediano, C., additional, Molina, F., additional, Javier, L., additional, Sara, A., additional, Minerva, A., additional, Romera, A., additional, Kihm, L., additional, Diekmann, C., additional, Seckinger, J., additional, Sommerer, C., additional, Morath, C., additional, Zeier, M., additional, Schwenger, V., additional, Teixeira, L., additional, Rodrigues, A., additional, Carvalho, M. J., additional, Cabrita, A., additional, and Mendonca, D., additional

Published
2011
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