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Background: Alcohol is one of the most abused substances in the world. Alcohol has been known to produce toxic effects in almost every organ system in the body, many of these medical conditions can be attributed to the direct toxic effect of alcohol and its metabolites, whereas others are indirect sequelae that may result from nutritional deficiency particularly thiamine. A neurological complication of alcohol dependence is extremely common and affects every level of neuroaxis including the Brain-Peripheral nervous system-Muscle. Aim & Objective: To quantify the number of different neurological disorders in alcohol-dependent patients and to the established relationship between the frequency of these disorders with type, duration, amount, and frequency of alcohol intake. Method & Material: A cross-sectional study was conducted in 100 alcoholics who came to tertiary care centers of central India in the 1-year duration. Demographic data, questions related to their alcohol consumption, and Neurological examination of all patients were done as pre-decided protocol. Informed consent was obtained from all patients. Data was entered and analyzed using appropriate software. Result: Study participants were mostly (70%) in the age group of 21 to 40 years, 87% resided in the urban area, 81% were Hindu. 78% were educated up to class 8th and 76% were employed with any kind of jobs. There were 64% of cases that had any kind of neurological manifestation, 20% had peripheral neuropathy and less than 10% has severe manifestation Korsakoff’s psychosis, and cerebellar degeneration. Conclusion: Neurological manifestations were common among alcohol dependents, but it variably depends on the amount, pattern, chronicity, and type of alcohol consumption. There is a need for further studies that specifically point out alcohol-related nervous manifestations.

In recent years demand of low power devices is increasing and the reason behind this is scaling of CMOS technology. Due to the scaling, size of the chip decreases and number of transistor in system on chip (SOC) increases and this phenomenon also apply on memories that are used in SOC. Generally the number of transistors used in chip to store data is more as compared to the number of transistors used for other function. So in future the need of low power memories is increasing and to design low power memories leakage power is attentive parameter to design low power devices because it plays a major role in increasing the total power consumption of the devices. In this paper, 7T simple SRAM and technique based 7T SRAM has been designed and parameters like total power and leakage power has been calculated. SRAM (Static Random Access Memory) is a type of memory that provide a link with CPU and designing of SRAM is very critical because it takes large part of power and area therefore to achieve low power SRAM we have designed Memristor based SRAM. Memristor is a forth missing non-linear resistor which acts as memory and it improves the power and speed. It is invented in 1971 by L. O. Chua and in this paper MTCMOS (Multi Threshold CMOS) technique is used, recently it is very famous in academia and industry. It is a power reducing technique that helps in reducing leakage power in the SRAM by turning of the inactive circuit domains. Designing and calculation of parameters of simple SRAM, Memristor based SRAM and MTCMOS based Memristor SRAM has been done with cadence virtuoso tool and that was done at 45 nm technology with the operating voltage of 0.7 volt.

Introduction: Burn injuries are a serious public health problem. In our study we have identified different epidemiological factors based on 10 years of our experience at a burn unit in central India and recommend some strategies to prevent burn injuries. Materials and Methods: This is a retrospective analysis (2001-2010) of database from burn unit of S.S. Medical College, Rewa, India. Results: 2499 patients with burn injury were analysed. 66.8% and 38.2% patients were females and males respectively, with a median age of 25 years. Flame (80.1%) was most common cause, home (96%) was most common place, traditional Indian stove (28.8%), kerosene lamp (26.7%), hot liquid (12.2%) and kerosene stove (10.4%) were common causes. Median Total Body Surface Area (TBSA) burn was 40.0%; females had significantly greater (P < 0.001) burn than males (median 50% vs 26.0%). High mortality (40.3%) seen; female sex (OR 3.22, 95% CI 2.65-3.92); young age (15-29 year) (OR 3.48, 95% CI 2.45-4.94); flame burn (OR 12.9, 95% CI 1.69-98.32); suicidal burn OR 6.82 95%CI 4.44-10.48) and TBSA > 76% (OR 3099, 95%CI 1302-7380) were significant risk factors for death. Median hospital stays was 8 days; shorter hospital stays seen among TBSA burn > 76% (2 days), suicidal intent (4 days), and those who expired (4 days). Septicemia (45.8%) and burn shock (41%) were the major cause for death. Conclusions: Cooking and lighting equipments are major cause of burn injury among females and young age group. Equipment modification to improve safety features and public awareness programs are necessary to reduce burn incidents.