1,000 results on '"Vijg, Jan"'
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2. Concurrent analysis of genome and transcriptome in one single cell
3. Polygenic prediction of human longevity on the supposition of pervasive pleiotropy
4. Analyzing somatic mutations by single-cell whole-genome sequencing
5. Author Correction: Rare genetic coding variants associated with human longevity and protection against age-related diseases
6. Aging of the eye: Lessons from cataracts and age-related macular degeneration
7. Chromosome instability and aneuploidy in the mammalian brain
8. Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging
9. Meeting Report: Aging Research and Drug Discovery
10. Judith Campisi (1948–2024), cell biologist who explored how cells age
11. Age‐related telomere attrition causes aberrant gene expression in sub‐telomeric regions
12. Somatic mutation burden in relation to aging and functional life span: implications for cellular reprogramming and rejuvenation
13. Mitigating age-related somatic mutation burden
14. Genetic wrinkles in time
15. ARDD 2020: from aging mechanisms to interventions
16. Why Gilgamesh failed: the mechanistic basis of the limits to human lifespan
17. Negative Selection Allows DNA Mismatch Repair-Deficient Mouse Fibroblasts In Vitro to Tolerate High Levels of Somatic Mutations
18. Single-cell analysis of somatic mutations in human bronchial epithelial cells in relation to aging and smoking
19. The shortness of human life constitutes its limit
20. A direct comparison of interphase FISH versus low-coverage single cell sequencing to detect aneuploidy reveals respective strengths and weaknesses.
21. A mechanism for inheriting radiation-induced DNA damage
22. Einstein-Nathan Shock Center: translating the hallmarks of aging to extend human health span
23. Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence
24. Parkinson’s disease patients display a DNA damage signature in blood that is predictive of disease progression
25. Genomic expansion of Aldh1a1 protects beavers against high metabolic aldehydes from lipid oxidation
26. Rare genetic coding variants associated with human longevity and protection against age-related diseases
27. A workflow for simultaneous DNA copy number and methylome analysis of inner cell mass and trophectoderm cells from human blastocysts
28. The central role of DNA damage in the ageing process
29. Whole Chromosome Instability induces senescence and promotes SASP.
30. Polygenic prediction of human longevity on the supposition of pervasive pleiotropy
31. Analyzing somatic mutations by single-cell whole-genome sequencing
32. Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan
33. Genetics of extreme human longevity to guide drug discovery for healthy ageing
34. Inducible aging in Hydra oligactis implicates sexual reproduction, loss of stem cells, and genome maintenance as major pathways
35. Concurrent analysis of genome and transcriptome in one single cell
36. Single-cell analysis of somatic mutation burden in mammary epithelial cells of pathogenic BRCA1/2 mutation carriers
37. Genome instability and aging: Cause or effect?
38. Impact papers on aging in 2009
39. Longevity-associated SMAD3 non-coding centenarian variant impairs a cell-type specific enhancer to reduce inflammation
40. DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale
41. Reduced frequency of clonal hematopoiesis in Parkinson′s disease
42. Expression of retrotransposons contributes to aging in Drosophila
43. Aging and Genome Maintenance: Lessons from the Mouse?
44. Clonally Expanded mtDNA Point Mutations are Abundant in Individual Cells of Human Tissues
45. Distinct Spectra of Somatic Mutations Accumulated with Age in Mouse Heart and Small Intestine
46. Loss of gene coordination as a stochastic cause of ageing
47. Mechanisms of cancer resistance in long-lived mammals
48. A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
49. Editorial: Somatic mutations, genome mosaicism and aging
50. Age is in the nucleus
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