1. Randomized Trial of a “Dynamic Choice” Patient-Centered Care Intervention for Mobile Persons With HIV in East Africa
- Author
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Ayieko, James, Balzer, Laura B, Inviolata, Colette, Kakande, Elijah, Opel, Fred, Wafula, Erick M, Kabami, Jane, Owaraganise, Asiphas, Mwangwa, Florence, Nakato, Hellen, Bukusi, Elizabeth A, Camlin, Carol S, Charlebois, Edwin D, Bacon, Melanie C, Petersen, Maya L, Kamya, Moses R, Havlir, Diane V, Chamie, Gabriel, and Team, SEARCH Study
- Subjects
Health Services and Systems ,Biomedical and Clinical Sciences ,Health Sciences ,Clinical Research ,Clinical Trials and Supportive Activities ,Infectious Diseases ,Sexually Transmitted Infections ,HIV/AIDS ,Infection ,Good Health and Well Being ,Female ,Humans ,Adult ,Male ,HIV Infections ,Kenya ,Uganda ,Ambulatory Care Facilities ,Patient-Centered Care ,mobile ,HIV retention ,ART possession ,viral suppression ,SEARCH Study Team ,Clinical Sciences ,Public Health and Health Services ,Virology ,Clinical sciences ,Epidemiology ,Public health - Abstract
BackgroundPersons with HIV (PWH) with high mobility face obstacles to HIV care engagement and viral suppression. We sought to understand whether a patient-centered intervention for mobile PWH would improve viral suppression and retention in care, and if so, which subgroups would benefit most.MethodsIn a randomized trial, we evaluated the effect of an intervention designed to address barriers to care among mobile (≥2 weeks out of community in previous year) PWH with viral nonsuppression or recent missed visits in Kenya and Uganda (NCT04810650). The intervention included dynamic choice of a "travel pack" (emergency antiretroviral therapy [ART] supply, discrete ART packaging, and travel checklist), multimonth and offsite refills, facilitated transfer to out-of-community clinics, and hotline access to a mobility coordinator. The primary outcome was viral suppression (
- Published
- 2024