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2. P166 Utility of lung clearance index (LCI2.5) as an outcome measure in cystic fibrosis clinical trials – perspectives of people with cystic fibrosis and LCI2.5 operators

Author

Kilarski, E., primary, Taylor, E., additional, Abkir, M., additional, Saunders, C., additional, Cunningham, S., additional, Lewis, S., additional, Neilson, A., additional, Ensor, H., additional, Miller, D., additional, Bowen, D., additional, Lacey, E., additional, Vogiatzis, I., additional, Allen, L., additional, Soilemezi, D., additional, Saynor, Z., additional, and Urquhart, D., additional

Published
2024
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3. EPS4.06 Safety of exercise as an airway clearance technique to replace chest physiotherapy in people with cystic fibrosis: preliminary insights from the ExACT-CF trial

Author

Saynor, Z., primary, Cunningham, S., additional, Lewis, S., additional, Neilson, A., additional, Ensor, H., additional, Miller, D., additional, Kilarski, E., additional, Bowen, D., additional, Lacey, E., additional, Vogiatzis, I., additional, Allen, L., additional, Soilemezi, D., additional, Morrison, L., additional, Taylor, E., additional, and Urquhart, D., additional

Published
2024
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4. P164 Utility of LCI2.5 as an outcome measure for people with cystic fibrosis of all ages – Experience from a pilot feasibility trial spanning adult and paediatric care

Author

Miller, D., primary, Kilarski, E., additional, Taylor, E., additional, Cunningham, S., additional, Lewis, S., additional, Neilson, A., additional, Bowen, D., additional, Lacey, E., additional, Abkir, M., additional, Saunders, C., additional, Vogiatzis, I., additional, Allen, L., additional, Soilemezi, D., additional, Saynor, Z., additional, and Urquhart, D., additional

Published
2024
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6. Α Respiratory Sound Database for the Development of Automated Classification

Author

Rocha, B. M., Filos, D., Mendes, L., Vogiatzis, I., Perantoni, E., Kaimakamis, E., Natsiavas, P., Oliveira, A., Jácome, C., Marques, A., Paiva, R. P., Chouvarda, I., Carvalho, P., Maglaveras, N., Magjarevic, Ratko, Series Editor, Ładyżyński, Piotr, Associate Editor, Ibrahim, Fatimah, Associate Editor, Lackovic, Igor, Associate Editor, Rock, Emilio Sacristan, Associate Editor, Maglaveras, Nicos, editor, Chouvarda, Ioanna, editor, and de Carvalho, Paulo, editor

Published
2018
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7. Long COVID research: an update from the PHOSP-COVID Scientific Summit

Author

Brightling, Christopher E, primary, Evans, Rachael A, additional, Singapuri, Amisha, additional, Smith, Nikki, additional, Wain, Louise V, additional, Brightling, C E, additional, Evans, R A, additional, Wain, L V, additional, Chalmers, J D, additional, Harris, V C, additional, Ho, L P, additional, Horsley, A, additional, Houchen-Wolloff, L, additional, Marks, M, additional, Raman, B, additional, Singapuri, A, additional, Barran, P, additional, Bingham, M, additional, Chilvers, E R, additional, Daynes, E, additional, Efstathiou, C M, additional, Elneima, O, additional, Guillen Guio, B, additional, Harrison, E M, additional, Jenkins, R G, additional, Liew, F, additional, Lone, N I, additional, Lord, J M, additional, McAuley, H J C, additional, McCann, G P, additional, Mitchell, J, additional, Plekhanova, T, additional, Russell, R J, additional, Saunders, R M, additional, Semple, M G, additional, Smith, N, additional, Trivedi, D, additional, Turtle, L, additional, Walker, S, additional, Abel, K, additional, Adamali, H, additional, Adeloye, D, additional, Adeyemi, O, additional, Adrego, R, additional, Aguilar Jimenez, L A, additional, Ahmad, S, additional, Ahmad Haider, N, additional, Ahmed, R, additional, Ahwireng, N, additional, Ainsworth, M, additional, Al-Sheklly, B, additional, Alamoudi, A, additional, Ali, M, additional, Aljaroof, M, additional, Allan, L, additional, Allen, R J, additional, Allerton, L, additional, Allsop, L, additional, Allt, AM, additional, Almeida, P, additional, Altmann, D, additional, Alvarez Corral, M, additional, Amoils, S, additional, Anderson, D, additional, Antoniades, C, additional, Arbane, G, additional, Arias, A, additional, Armour, C, additional, Armstrong, L, additional, Armstrong, N, additional, Arnold, D, additional, Arnold, H, additional, Ashish, A, additional, Ashworth, A, additional, Ashworth, M, additional, Aslani, S, additional, Assefa-Kebede, H, additional, Atkin, P, additional, Atkin, C, additional, Aul, R, additional, Aung, H, additional, Austin, L, additional, Avram, C, additional, Ayoub, A, additional, Babores, M, additional, Baggott, R, additional, Bagshaw, J, additional, Baguley, D, additional, Bailey, L, additional, Baillie, J K, additional, Bain, S, additional, Bakali, M, additional, Bakau, M, additional, Baldry, E, additional, Baldwin, M, additional, Baldwin, D, additional, Ballard, C, additional, Banerjee, A, additional, Bang, D, additional, Barker, R E, additional, Barman, L, additional, Barratt, S, additional, Barrett, F, additional, Basire, D, additional, Basu, N, additional, Bates, M, additional, Bates, A, additional, Batterham, R, additional, Baxendale, H, additional, Baxter, G, additional, Bayes, H, additional, Beadsworth, M, additional, Beckett, P, additional, Beggs, M, additional, Begum, M, additional, Beirne, P, additional, Bell, M, additional, Bell, R, additional, Bennett, K, additional, Beranova, E, additional, Bermperi, A, additional, Berridge, A, additional, Berry, C, additional, Betts, S, additional, Bevan, E, additional, Bhui, K, additional, Birchall, K, additional, Bishop, L, additional, Bisnauthsing, K, additional, Blaikely, J, additional, Bloss, A, additional, Bolger, A, additional, Bolton, C E, additional, Bonnington, J, additional, Botkai, A, additional, Bourne, C, additional, Bourne, M, additional, Bramham, K, additional, Brear, L, additional, Breen, G, additional, Breeze, J, additional, Breeze, K, additional, Briggs, A, additional, Bright, E, additional, Brill, S, additional, Brindle, K, additional, Broad, L, additional, Broadley, A, additional, Brookes, C, additional, Broome, M, additional, Brown, V, additional, Brown, M, additional, Brown, J, additional, Brown, A, additional, Brown, J S, additional, Brugha, T, additional, Brunskill, N, additional, Buch, M, additional, Buckley, P, additional, Bularga, A, additional, Bullmore, E, additional, Bunker, J, additional, Burden, L, additional, Burdett, T, additional, Burn, D, additional, Burns, G, additional, Burns, A, additional, Busby, J, additional, Butcher, R, additional, Butt, A, additional, Byrne, S, additional, Cairns, P, additional, Calder, P C, additional, Calvelo, E, additional, Carborn, H, additional, Card, B, additional, Carr, C, additional, Carr, L, additional, Carson, G, additional, Carter, P, additional, Casey, A, additional, Cassar, M, additional, Cavanagh, J, additional, Chablani, M, additional, Chalder, T, additional, Chambers, R C, additional, Chan, F, additional, Channon, K M, additional, Chapman, K, additional, Charalambou, A, additional, Chaudhuri, N, additional, Checkley, A, additional, Chen, J, additional, Cheng, Y, additional, Chetham, L, additional, Childs, C, additional, Chinoy, H, additional, Chiribiri, A, additional, Chong-James, K, additional, Choudhury, N, additional, Choudhury, G, additional, Chowienczyk, P, additional, Christie, C, additional, Chrystal, M, additional, Clark, C, additional, Clark, D, additional, Clarke, J, additional, Clohisey, S, additional, Coakley, G, additional, Coburn, Z, additional, Coetzee, S, additional, Cole, J, additional, Coleman, C, additional, Conneh, F, additional, Connell, D, additional, Connolly, B, additional, Connor, L, additional, Cook, A, additional, Cooper, S, additional, Cooper, B, additional, Cooper, J, additional, Copeland, D, additional, Cosier, T, additional, Coulding, M, additional, Coupland, C, additional, Cox, E, additional, Craig, T, additional, Crisp, P, additional, Cristiano, D, additional, Crooks, M G, additional, Cross, A, additional, Cruz, I, additional, Cullinan, P, additional, Cuthbertson, D, additional, Daines, L, additional, Dalton, M, additional, Daly, P, additional, Daniels, A, additional, Dark, P, additional, Dasgin, J, additional, David, C, additional, David, A, additional, Davies, F, additional, Davies, E, additional, Davies, K, additional, Davies, G, additional, Davies, G A, additional, Davies, M J, additional, Dawson, J, additional, Dawson, C, additional, De Soyza, A, additional, Deakin, B, additional, Deans, A, additional, Deas, C, additional, Deery, J, additional, Defres, S, additional, Dell, A, additional, Dempsey, K, additional, Denneny, E, additional, Dennis, J, additional, Dewar, A, additional, Dharmagunawardena, R, additional, Diar-Bakerly, N, additional, Dickens, C, additional, Dipper, A, additional, Diver, S, additional, Diwanji, S N, additional, Dixon, M, additional, Djukanovic, R, additional, Dobson, H, additional, Dobson, S L, additional, Docherty, A B, additional, Donaldson, A, additional, Dong, T, additional, Dormand, N, additional, Dougherty, A, additional, Dowling, R, additional, Drain, S, additional, Draxlbauer, K, additional, Drury, K, additional, Dulawan, P, additional, Dunleavy, A, additional, Dunn, S, additional, Dupont, C, additional, Earley, J, additional, Easom, N, additional, Echevarria, C, additional, Edwards, S, additional, Edwardson, C, additional, El-Taweel, H, additional, Elliott, A, additional, Elliott, K, additional, Ellis, Y, additional, Elmer, A, additional, Evans, T, additional, Evans, R I, additional, Evans, D, additional, Evans, R, additional, Evans, H, additional, Evans, J, additional, Evenden, C, additional, Evison, L, additional, Fabbri, L, additional, Fairbairn, S, additional, Fairman, A, additional, Fallon, K, additional, Faluyi, D, additional, Favager, C, additional, Fayzan, T, additional, Featherstone, J, additional, Felton, T, additional, Ferreira, V, additional, Finch, J, additional, Finney, S, additional, Finnigan, J, additional, Finnigan, L, additional, Fisher, H, additional, Fletcher, S, additional, Flockton, R, additional, Flynn, M, additional, Foot, H, additional, Foote, D, additional, Ford, A, additional, Forton, D, additional, Fraile, E, additional, Francis, C, additional, Francis, R, additional, Francis, S, additional, Frankel, A, additional, Fraser, E, additional, Free, R, additional, French, N, additional, Fu, X, additional, Fuld, J, additional, Furniss, J, additional, Garner, L, additional, Gautam, N, additional, Geddes, J R, additional, George, J, additional, George, P, additional, Gibbons, M, additional, Gill, R, additional, Gill, M, additional, Gilmour, L, additional, Gleeson, F, additional, Glossop, J, additional, Glover, S, additional, Goodman, N, additional, Goodwin, C, additional, Gooptu, B, additional, Gordon, H, additional, Gorsuch, T, additional, Greatorex, M, additional, Greenhaff, P L, additional, Greenhalf, W, additional, Greenhalgh, A, additional, Greening, N J, additional, Greenwood, J, additional, Gregory, R, additional, Gregory, H, additional, Grieve, D, additional, Griffin, D, additional, Griffiths, L, additional, Guerdette, A-M, additional, Gummadi, M, additional, Gupta, A, additional, Gurram, S, additional, Guthrie, E, additional, Guy, Z, additional, Hadley, K, additional, Haggar, A, additional, Hainey, K, additional, Hairsine, B, additional, Haldar, P, additional, Hall, L, additional, Hall, I, additional, Halling-Brown, M, additional, Hamil, R, additional, Hancock, A, additional, Hancock, K, additional, Hanley, N A, additional, Haq, S, additional, Hardwick, H E, additional, Hardy, T, additional, Hardy, E, additional, Hargadon, B, additional, Harrington, K, additional, Harris, E, additional, Harrison, P, additional, Hart, N, additional, Harvey, A, additional, Harvey, M, additional, Harvie, M, additional, Haslam, L, additional, Hastie, C, additional, Havinden-Williams, M, additional, Hawkes, J, additional, Hawkings, N, additional, Haworth, J, additional, Hayday, A, additional, Haynes, M, additional, Hazeldine, J, additional, Hazelton, T, additional, Heaney, L G, additional, Heeley, C, additional, Heeney, J L, additional, Heightman, M, additional, Heller, S, additional, Henderson, M, additional, Henson, H, additional, Hesselden, L, additional, Hewitt, M, additional, Highett, V, additional, Hillman, T, additional, Hiwot, T, additional, Hoare, M, additional, Hoare, A, additional, Hockridge, J, additional, Hogarth, P, additional, Holbourn, A, additional, Holden, S, additional, Holdsworth, L, additional, Holgate, D, additional, Holland, M, additional, Holloway, L, additional, Holmes, K, additional, Holmes, M, additional, Holroyd-Hind, B, additional, Holt, L, additional, Hormis, A, additional, Hosseini, A, additional, Hotopf, M, additional, Howard, L S, additional, Howard, K, additional, Howell, A, additional, Hufton, E, additional, Hughes, R A, additional, Hughes, J, additional, Hughes, A D, additional, Humphries, A, additional, Huneke, N, additional, Hurditch, E, additional, Hurst, J, additional, Husain, M, additional, Hussell, T, additional, Hutchinson, J, additional, Ibrahim, W, additional, Ilyas, F, additional, Ingham, J, additional, Ingram, L, additional, Ionita, D, additional, Isaacs, K, additional, Ismail, K, additional, Jackson, T, additional, Jacob, J, additional, James, W Y, additional, Jang, W, additional, Jarman, C, additional, Jarrold, I, additional, Jarvis, H, additional, Jastrub, R, additional, Jayaraman, B, additional, Jezzard, P, additional, Jiwa, K, additional, Johnson, C, additional, Johnson, S, additional, Johnston, D, additional, Jolley, C J, additional, Jones, S, additional, Jones, H, additional, Jones, L, additional, Jones, I, additional, Jones, G, additional, Jones, M G, additional, Jones, D, additional, Jose, S, additional, Kabir, T, additional, Kaltsakas, G, additional, Kamwa, V, additional, Kanellakis, N, additional, Kaprowska, S, additional, Kausar, Z, additional, Keenan, N, additional, Kelly, S, additional, Kemp, G, additional, Kerr, S, additional, Kerslake, H, additional, Key, A L, additional, Khan, F, additional, Khunti, K, additional, Kilroy, S, additional, King, B, additional, King, C, additional, Kingham, L, additional, Kirk, J, additional, Kitterick, P, additional, Klenerman, P, additional, Knibbs, L, additional, Knight, S, additional, Knighton, A, additional, Kon, O, additional, Kon, S, additional, Kon, S S, additional, Korszun, A, additional, Koychev, I, additional, Kurasz, C, additional, Kurupati, P, additional, Laing, C, additional, Lamlum, H, additional, Landers, G, additional, Langenberg, C, additional, Lavelle-Langham, L, additional, Lawrie, A, additional, Lawson, C, additional, Layton, A, additional, Lea, A, additional, Leavy, O C, additional, Lee, J-H, additional, Lee, E, additional, Lee, D, additional, Leitch, K, additional, Lenagh, R, additional, Lewis, V, additional, Lewis, J, additional, Lewis, K E, additional, Lewis, D, additional, Lewis-Burke, N, additional, Li, X, additional, Light, T, additional, Lightstone, L, additional, Lilaonitkul, W, additional, Lim, L, additional, Linford, S, additional, Lingford-Hughes, A, additional, Lipman, M, additional, Liyanage, K, additional, Lloyd, A, additional, Logan, S, additional, Lomas, D, additional, Loosley, R, additional, Lota, H, additional, Lovegrove, W, additional, Lucey, A, additional, Lucy, L, additional, Lukaschuk, E, additional, Lye, A, additional, Lynch, C, additional, MacDonald, S, additional, MacGowan, G, additional, Macharia, I, additional, Mackie, J, additional, Macliver, L, additional, Madathil, S, additional, Madzamba, G, additional, Magee, N, additional, Magtoto, M M, additional, Mairs, N, additional, Majeed, N, additional, Major, E, additional, Malein, F, additional, Malim, M, additional, Mallison, G, additional, Man, W D-C, additional, Mandal, S, additional, Mangion, K, additional, Manisty, C, additional, Manley, R, additional, March, K, additional, Marciniak, S, additional, Marino, P, additional, Mariveles, M, additional, Marouzet, E, additional, Marsh, S, additional, Marshall, M, additional, Marshall, B, additional, Martin, J, additional, Martineau, A, additional, Martinez, L M, additional, Maskell, N, additional, Matila, D, additional, Matimba-Mupaya, W, additional, Matthews, L, additional, Mbuyisa, A, additional, McAdoo, S, additional, McAllister-Williams, H, additional, McArdle, P, additional, McArdle, A, additional, McAulay, D, additional, McCormick, W, additional, McCormick, J, additional, McCourt, P, additional, McCracken, C, additional, McGarvey, L, additional, McGee, C, additional, Mcgee, K, additional, McGinness, J, additional, McGlynn, K, additional, McGovern, A, additional, McGuinness, H, additional, McInnes, I B, additional, McIntosh, J, additional, McIvor, E, additional, McIvor, K, additional, McLeavey, L, additional, McMahon, A, additional, McMahon, M J, additional, McMorrow, L, additional, Mcnally, T, additional, McNarry, M, additional, McNeill, J, additional, McQueen, A, additional, McShane, H, additional, Mears, C, additional, Megson, C, additional, Megson, S, additional, Mehta, P, additional, Meiring, J, additional, Melling, L, additional, Mencias, M, additional, Menke, R, additional, Menzies, D, additional, Merida Morillas, M, additional, Michael, A, additional, Michael, B, additional, Miller, C A, additional, Milligan, L, additional, Mills, N L, additional, Mills, C, additional, Mills, G, additional, Milner, L, additional, Misra, S, additional, Mohamed, A, additional, Mohamed, N, additional, Mohammed, S, additional, Molyneaux, P L, additional, Monteiro, W, additional, Moriera, S, additional, Morley, A, additional, Morrison, L, additional, Morriss, R, additional, Morrow, A, additional, Moss, P, additional, Moss, A J, additional, Motohashi, K, additional, Msimanga, N, additional, Mukaetova-Ladinska, E, additional, Munawar, U, additional, Murira, J, additional, Nanda, U, additional, Nassa, H, additional, Nasseri, M, additional, Nathu, R, additional, Neal, A, additional, Needham, R, additional, Neill, P, additional, Neubauer, S, additional, Newby, D E, additional, Newell, H, additional, Newman, J, additional, Newman, T, additional, Newton-Cox, A, additional, Nichols, T E, additional, Nicholson, T, additional, Nicolaou, C, additional, Nicoll, D, additional, Nikolaidis, A, additional, Nikolaidou, C, additional, Nolan, C M, additional, Noonan, M J, additional, Norman, C, additional, Novotny, P, additional, Nunag, J L, additional, Nwafor, L, additional, Nwanguma, U, additional, Nyaboko, J, additional, O'Brien, C, additional, O'Donnell, K, additional, O'Regan, D P, additional, O'Brien, L, additional, Odell, N, additional, Ogbole, G, additional, Ogg, G, additional, Olaosebikan, O, additional, Oliver, C, additional, Omar, Z, additional, Openshaw, P J M, additional, Orriss-Dib, L, additional, Osborne, L, additional, Osbourne, R, additional, Ostermann, M, additional, Overton, C, additional, Owen, J, additional, Oxton, J, additional, Pack, J, additional, Pacpaco, E, additional, Paddick, S, additional, Painter, S, additional, Pakzad, A, additional, Palmer, S, additional, Papineni, P, additional, Paques, K, additional, Paradowski, K, additional, Pareek, M, additional, Parekh, D, additional, Parfrey, H, additional, Pariante, C, additional, Parker, S, additional, Parkes, M, additional, Parmar, J, additional, Patale, S, additional, Patel, M, additional, Patel, B, additional, Patel, S, additional, Pattenadk, D, additional, Pavlides, M, additional, Payne, S, additional, Pearce, L, additional, Pearl, J E, additional, Peckham, D, additional, Pendlebury, J, additional, Peng, Y, additional, Pennington, C, additional, Peralta, I, additional, Perkins, E, additional, Peterkin, Z, additional, Peto, T, additional, Petousi, N, additional, Petrie, J, additional, Pfeffer, P, additional, Phipps, J, additional, Piechnik, S, additional, Pimm, J, additional, Piper Hanley, K, additional, Pius, R, additional, Plant, H, additional, Plein, S, additional, Plowright, M, additional, Poinasamy, K, additional, Polgar, O, additional, Poll, L, additional, Porter, J, additional, Porter, J C, additional, Portukhay, S, additional, Powell, N, additional, Prabhu, A, additional, Pratt, J, additional, Price, A, additional, Price, C, additional, Price, L, additional, Price, D, additional, Prickett, A, additional, Propescu, I, additional, Propescu, J, additional, Prosper, S, additional, Pugmire, S, additional, Quaid, S, additional, Quigley, J, additional, Quint, J, additional, Qureshi, H, additional, Qureshi, I N, additional, Radhakrishnan, K, additional, Rahman, N M, additional, Ralser, M, additional, Ramos, H, additional, Ramos, A, additional, Rangeley, J, additional, Rangelov, B, additional, Ratcliffe, L, additional, Ravencroft, P, additional, Reddington, A, additional, Reddy, R, additional, Reddy, A, additional, Redfearn, H, additional, Redwood, D, additional, Reed, A, additional, Rees, M, additional, Rees, T, additional, Regan, K, additional, Reynolds, W, additional, Ribeiro, C, additional, Richards, A, additional, Richardson, E, additional, Richardson, M, additional, Rivera-Ortega, P, additional, Roberts, K, additional, Robertson, E, additional, Robinson, L, additional, Robinson, E, additional, Roche, L, additional, Roddis, C, additional, Rodger, J, additional, Rogers, N, additional, Ross, G, additional, Ross, A, additional, Rossdale, J, additional, Rostron, A, additional, Rowe, A, additional, Rowland, J, additional, Rowland, M J, additional, Rowland, A, additional, Rowland-Jones, S L, additional, Roy, M, additional, Roy, K, additional, Rudan, I, additional, Russell, R, additional, Russell, E, additional, Saalmink, G, additional, Sabit, R, additional, Sage, E K, additional, Samakomva, T, additional, Samani, N, additional, Samat, A A, additional, Sampson, C, additional, Samuel, K, additional, Samuel, R, additional, Sanders, Z B, additional, Sanderson, A, additional, Sapey, E, additional, Saralaya, D, additional, Sargant, J, additional, Sarginson, C, additional, Sass, T, additional, Sattar, N, additional, Saunders, K, additional, Saunders, P, additional, Saunders, L C, additional, Savill, H, additional, Saxon, W, additional, Sayer, A, additional, Schronce, J, additional, Schwaeble, W, additional, Scott, J T, additional, Scott, K, additional, Selby, N, additional, Sereno, M, additional, Sewell, T A, additional, Shah, K, additional, Shah, A, additional, Shah, P, additional, Shankar-Hari, M, additional, Sharma, M, additional, Sharpe, C, additional, Sharpe, M, additional, Shashaa, S, additional, Shaw, A, additional, Shaw, V, additional, Shaw, K, additional, Sheikh, A, additional, Shelton, S, additional, Shenton, L, additional, Shevket, K, additional, Shikotra, A, additional, Short, J, additional, Siddique, S, additional, Siddiqui, S, additional, Sidebottom, J, additional, Sigfrid, L, additional, Simons, G, additional, Simpson, N, additional, Simpson, J, additional, Singh, S, additional, Singh, C, additional, Singh, S J, additional, Sissons, D, additional, Skeemer, J, additional, Slack, K, additional, Smith, D, additional, Smith, A, additional, Smith, J, additional, Smith, L, additional, Smith, S, additional, Soares, M, additional, Solano, T S, additional, Solly, R, additional, Solstice, AR, additional, Soulsby, T, additional, Southern, D, additional, Sowter, D, additional, Spears, M, additional, Spencer, L G, additional, Speranza, F, additional, Stadon, L, additional, Stanel, S, additional, Steeds, R, additional, Steele, N, additional, Steiner, M, additional, Stensel, D, additional, Stephens, G, additional, Stephenson, L, additional, Stern, M, additional, Stewart, I, additional, Stimpson, R, additional, Stockdale, S, additional, Stockley, J, additional, Stoker, W, additional, Stone, R, additional, Storrar, W, additional, Storrie, A, additional, Storton, K, additional, Stringer, E, additional, Strong-Sheldrake, S, additional, Stroud, N, additional, Subbe, C, additional, Sudlow, C L, additional, Suleiman, Z, additional, Summers, C, additional, Summersgill, C, additional, Sutherland, D, additional, Sykes, D L, additional, Sykes, R, additional, Talbot, N, additional, Tan, A L, additional, Tarusan, L, additional, Tavoukjian, V, additional, Taylor, J, additional, Taylor, A, additional, Taylor, C, additional, Taylor, J P, additional, Te, A, additional, Tedd, H, additional, Tee, CJ, additional, Teixeira, J, additional, Tench, H, additional, Terry, S, additional, Thackray-Nocera, S, additional, Thaivalappil, F, additional, Thamu, B, additional, Thickett, D, additional, Thomas, D C, additional, Thomas, S, additional, Thomas, C, additional, Thomas, A K, additional, Thomas-Woods, T, additional, Thompson, A A R, additional, Thompson, T, additional, Thornton, T, additional, Thorpe, M, additional, Thwaites, R S, additional, Tilley, J, additional, Tinker, N, additional, Tiongson, G F, additional, Tobin, M, additional, Tomlinson, J, additional, Tong, C, additional, Toshner, M, additional, Touyz, R, additional, Treibel, T, additional, Tripp, K A, additional, Tunnicliffe, E M, additional, Turnbull, A, additional, Turner, K, additional, Turner, S, additional, Turner, V, additional, Turner, E, additional, Turney, S, additional, Turton, H, additional, Ugoji, J, additional, Ugwuoke, R, additional, Upthegrove, R, additional, Valabhji, J, additional, Ventura, M, additional, Vere, J, additional, Vickers, C, additional, Vinson, B, additional, Vogiatzis, I, additional, Wade, E, additional, Wade, P, additional, Wainwright, T, additional, Wajero, L O, additional, Walder, S, additional, Wall, E, additional, Wallis, T, additional, Walmsley, S, additional, Walsh, S, additional, Walsh, J A, additional, Warburton, L, additional, Ward, T J C, additional, Warwick, K, additional, Wassall, H, additional, Waterson, S, additional, Watson, L, additional, Watson, E, additional, Watson, J, additional, Webster, M, additional, Weir McCall, J, additional, Welch, H, additional, Welch, C, additional, Welsh, B, additional, Wessely, S, additional, West, S, additional, Weston, H, additional, Wheeler, H, additional, White, S, additional, Whitehead, V, additional, Whitney, J, additional, Whittaker, S, additional, Whittam, B, additional, Whitworth, V, additional, Wight, A, additional, Wild, J M, additional, Wilkins, M, additional, Wilkinson, D, additional, Williams, N, additional, Williams, B, additional, Williams, J, additional, Williams-Howard, S A, additional, Willicombe, M, additional, Willis, G, additional, Willoughby, J, additional, Wilson, A, additional, Wilson, I, additional, Wilson, D, additional, Window, N, additional, Witham, M, additional, Wolf-Roberts, R, additional, Wood, C, additional, Woodhead, F, additional, Woods, J, additional, Wootton, D G, additional, Wormleighton, J, additional, Worsley, J, additional, Wraith, D, additional, Wrey Brown, C, additional, Wright, C, additional, Wright, S, additional, Wright, L, additional, Wyles, J, additional, Wynter, I, additional, Xie, C, additional, Xu, M, additional, Yasmin, N, additional, Yasmin, S, additional, Yates, T, additional, Yip, K P, additional, Young, S, additional, Young, B, additional, Young, A, additional, Yousuf, A J, additional, Zawia, A, additional, Zeidan, L, additional, Zhao, B, additional, Zheng, B, additional, and Zongo, O, additional

Published
2023
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8. Progression of physical inactivity in COPD patients: the effect of time and climate conditions – a multicenter prospective cohort study

Author

Boutou AK, Raste Y, Demeyer H, Troosters T, Polkey MI, Vogiatzis I, Louvaris Z, Rabinovich RA, van der Molen T, Garcia-Aymerich J, and Hopkinson NS

Subjects
physical activity, chronic obstructive pulmonary disease, elapsed time, climate, Diseases of the respiratory system, RC705-779
Abstract

Afroditi K Boutou,1,2,* Yogini Raste,1,* Heleen Demeyer,3 Thierry Troosters,3 Michael I Polkey,1 Ioannis Vogiatzis,4,5 Zafeiris Louvaris,4 Roberto A Rabinovich,6 Thys van der Molen,7 Judith Garcia-Aymerich,8–10 Nicholas S Hopkinson1 On behalf of the PROactive consortium1National Institute for Health Research Respiratory Biomedical Research Unit, Royal Brompton and Harefield NHS Foundation Trust and Imperial College, London, UK; 2Department of Respiratory Medicine, “G. Papanikolaou” Hospital, Thessaloniki, Greece; 3Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences and Respiratory Division, University Hospital Leuven, Leuven, Belgium; 4First Department of Respiratory Medicine, National & Kapodistrian University of Athens, Athens, Greece; 5Department of Sport, Exercise and Rehabilitation, Northumbria University, Newcastle, UK; 6ELEGI Colt Laboratory, Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK; 7Department of General Practice, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; 8ISGlobal, Barcelona, Spain; 9Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain; 10Universitat Pompeu Fabra (UPF), Barcelona, SpainCorrespondence: Afroditi K BoutouDepartment of Respiratory Medicine, “G. Papanikolaou” Hospital, Exohi, Thessaloniki 57010, GreeceTel +30 231 330 7277Email afboutou@yahoo.com*These authors contributed equally to this workPurpose: Longitudinal data on the effect of time and environmental conditions on physical activity (PA) among COPD patients are currently scarce, but this is an important factor in the design of trials to test interventions that might impact on it. Thus, we aimed to assess the effect of time and climate conditions (temperature, day length and rainfall) on progression of PA in a cohort of COPD patients.Patients and methods: This is a prospective, multicenter, cohort study undertaken as part of the EU/IMI PROactive project, in which we assessed 236 COPD patients simultaneously wearing two activity monitors (Dynaport MiniMod and Actigraph GT3X). A multivariable generalized linear model analysis was conducted to describe the effect of the explanatory variables on PA measures, over three time points (baseline, 6 and 12 months).Results: At 12 months (n=157; FEV1% predicted=57.7±21.9) there was a significant reduction in all PA measures (Actigraph step count (4284±3533 vs 3533±293)), Actigraph moderate- to vigorous-intensity PA ratio (8.8 (18.8) vs 6.1 (15.7)), Actigraph vector magnitude units (374,902.4 (265,269) vs 336,240 (214,432)), MiniMod walking time (59.1 (34.9) vs 56.9 (38.7) mins) and MiniMod PA intensity (0.183 (0) vs 0.181 (0)). Time had a significant, negative effect on most PA measures in multivariable analysis, after correcting for climate factors, study center, age, FEV1% predicted, 6MWD and other disease severity measures. Rainfall was the only climate factor with a negative effect on most PA parameters.Conclusion: COPD patients demonstrate a significant decrease in PA over 1 year follow-up, which is further affected by hours of rainfall, but not by other climate considerations.Keywords: physical activity, chronic obstructive pulmonary disease, elapsed time, climate

Published
2019

9. The likelihood of improving physical activity after pulmonary rehabilitation is increased in patients with COPD who have better exercise tolerance

Author

Osadnik CR, Loeckx M, Louvaris Z, Demeyer H, Langer D, Rodrigues FM, Janssens W, Vogiatzis I, and Troosters T

Subjects
Exercise and Pulmonary Rehabilitation, COPD, Physical activity, Clinical Respiratory Medicine, Diseases of the respiratory system, RC705-779
Abstract

Christian R Osadnik,1–4,* Matthias Loeckx,1,5,6,* Zafeiris Louvaris,1,7 Heleen Demeyer,1,6 Daniel Langer,1,6 Fernanda M Rodrigues,1,6 Wim Janssens,6,8 Ioannis Vogiatzis,7,9 Thierry Troosters1,6 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; 2Department of Physiotherapy, Monash University, Melbourne, Victoria, Australia; 3Monash Lung and Sleep, Monash Health, Melbourne, Victoria, Australia; 4Institute for Breathing and Sleep, Melbourne, Victoria, Australia; 5Department of Physiotherapy, LUNEX International University of Health, Exercise and Sports, Differdange, Luxembourg; 6Respiratory Division, University Hospitals, KU Leuven, Leuven, Belgium; 7Faculty of Physical Education and Sports Sciences, National and Kapodistrian University of Athens, Athens, Greece; 8Department of Chronic Disease, Metabolism and Aging, KU Leuven, Leuven, Belgium; 9Department of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK *These authors contributed equally to this work Purpose: Pulmonary rehabilitation (PR) enhances exercise tolerance in patients with COPD; however, improvements in physical activity (PA) are not guaranteed. This study explored the relationship between baseline exercise tolerance and changes in PA after PR.Materials and methods: Patient data from prospective clinical trials in the PR settings of Athens and Leuven (2008–2016) were analyzed. Validated PA monitors were worn for 1 week before and after a 12-week program. The proportion of patients who improved PA levels ≥1,000 steps/day (“PA responders”) after PR was compared between those with initial 6-minute walk distance [6MWDi]

Published
2018

22. Rehabilitation facilitates the natural recovery of symptoms, mental health and quality of life outcomes post COVID-19.

Author

Asimakos, A, primary, Spetsioti, S, additional, Vogiatzis, I, additional, Mavronasou, A, additional, Gounopoulos, P, additional, Siousioura, D, additional, Dima, E, additional, Gianiou, N, additional, Sigala, I, additional, Pappa, S, additional, Zakynthinos, S, additional, Kotanidou, A, additional, and Katsaounou, P, additional

Published
2022
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29. Epidemiology, reperfusion management, and outcomes of patients with myocardial infarction in Greece: The ILIAKTIS study

Author

Kanakakis, Ioannis, primary, Stafylas, Panagiotis, additional, Tsigkas, Grigorios, additional, Nikas, Dimitris, additional, Synetos, Andreas, additional, Avramidis, Dimitrios, additional, Tsiafoutis, Ioannis, additional, Dagre, Anna, additional, Tzikas, Stergios, additional, Latsios, Giorgos, additional, Patsourakos, Nikos, additional, Sanidas, Ilias, additional, Skalidis, Emmanouil, additional, Pipilis, Athanasios, additional, Bamidis, Panagiotis, additional, Davlouros, Periklis, additional, Kanakakis, I., additional, Tselegkidi, M.E., additional, Sertedaki, E., additional, Mamarelis, I., additional, Fraggos, E., additional, Mantzouranis, E., additional, Karvounis, C., additional, Manolis, A.J., additional, Chatzilymperis, G., additional, Chiotelis, I., additional, Gryllis, D., additional, Poulimenos, L.E., additional, Triantafyllis, A., additional, Alexopoulos, D., additional, Varlamos, C., additional, Almpanis, G., additional, Aggeli, A., additional, Sakkas, A., additional, Trikas, A., additional, Tsiamis, S., additional, Triantafylloy, K., additional, Mpenia, D., additional, Oikonomou, D., additional, Papadopoulou, E., additional, Avramidis, D., additional, Kousta, M., additional, Moulianitaki, E., additional, Poulianitis, G., additional, Mavrou, G., additional, Latsios, G., additional, Synetos, A., additional, Tousoulis, D., additional, Kafkas, N., additional, Godwin, S., additional, Mertzanos, G., additional, Koytouzis, M., additional, Tsiafoutis, I., additional, Papadopoulos, A., additional, Tsoumeleas, A., additional, Barbetseas, I., additional, Sanidas, I., additional, Athanasiou, A., additional, Paizis, I., additional, Kakkavas, A., additional, Papafanis, T., additional, Mantas, I., additional, Neroutsos, G., additional, Gkoliopoulou, A., additional, Tafrali, V., additional, Diakakis, G., additional, Grammatikopoulos, K., additional, Sinanis, T., additional, Kartalis, A., additional, Afendoulis, D., additional, Voutas, P., additional, Kardamis, C., additional, Doulis, A., additional, Kalantzis, N., additional, Vergis, K., additional, Chasikidis, C., additional, Armatas, G., additional, Damelou, A., additional, Ntogka, M., additional, Serafetinidis, I., additional, Zagkas, K., additional, Tselempis, T., additional, Makridis, P., additional, Karantoumanis, I., additional, Karapatsoudi, E., additional, Oikonomou, K., additional, Foukarakis, E., additional, Kafarakis, P., additional, Pitarokoilis, M., additional, Rogdakis, E., additional, Stavrakis, S., additional, Koudounis, G., additional, Karampetsos, V., additional, Lionakis, N., additional, Panotopoulos, C., additional, Svoronos, D., additional, Tsorlalis, I., additional, Tsatiris, K., additional, Beneki, E., additional, Papadopoulos, N., additional, Sawafta, A., additional, Kozatsani, D., additional, Spyromitros, G., additional, Bostanitis, I., additional, Dimitriadis, G., additional, Nikoloulis, N., additional, Kampouridis, N., additional, Giampatzis, V., additional, Patsilinakos, S., additional, Andrikou, E., additional, Katsiadas, N., additional, Papanagnou, G., additional, Kotsakis, A., additional, Ioannidis, E., additional, Platogiannis, N., additional, Psychari, S., additional, Pissimissis, E., additional, Gavrielatos, G., additional, Maritsa, D., additional, Papakonstantinou, N., additional, Patsourakos, N., additional, Oikonomou, G., additional, Katsanou, K., additional, Lazaris, E., additional, Moschos, N., additional, Giakoumakis, T., additional, Papagiannis, N., additional, Goudis, C., additional, Daios, S., additional, Devliotis, K., additional, Dimitriadis, F., additional, Giannadaki, M., additional, Savvidis, M., additional, Tsinopoulos, G., additional, Zarifis, I., additional, Askalidou, T., additional, Vasileiadis, I., additional, Kleitsiotou, P., additional, Sidiropoulos, S., additional, Tsaousidis, A., additional, Tzikas, S., additional, Vassilikos, V., additional, Papadopoulos, C., additional, Zarvalis, Ε., additional, Gogos, C., additional, Moschovidis, V., additional, Styliadis, I., additional, Laschos, V., additional, Spathoulas, K., additional, Vogiatzis, I., additional, Kasmeridis, C., additional, Pittas, S., additional, Sdogkos, E., additional, Dagre, A., additional, Mpounas, P., additional, Rodis, I., additional, Pipilis, A., additional, Konstantinidis, S., additional, Makrygiannis, S., additional, Masdrakis, A., additional, Magginas, A., additional, Sevastos, G., additional, Katsimagklis, G., additional, Skalidis, E., additional, Petousis, S., additional, Davlouros, P., additional, Tsigkas, G., additional, Hahalis, G., additional, Koufou, E., additional, Tziakas, D., additional, Chalikias, G., additional, Thomaidi, A., additional, Stakos, D., additional, Chotidis, A., additional, Nikas, D., additional, Sakellariou, X., additional, Skoularigkis, I., additional, Dimos, A., additional, Iakovis, N., additional, Mpourazana, A., additional, Zagouras, A., additional, Lygkouri, G., additional, Bamidis, P., additional, Lagakis, P., additional, Spachos, D., additional, Stafylas, P., additional, Chalitsios, C.V., additional, Karaiskou, M., additional, and Tychala, C., additional

Published
2022
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31. Α Respiratory Sound Database for the Development of Automated Classification

Author

Rocha, B. M., primary, Filos, D., additional, Mendes, L., additional, Vogiatzis, I., additional, Perantoni, E., additional, Kaimakamis, E., additional, Natsiavas, P., additional, Oliveira, A., additional, Jácome, C., additional, Marques, A., additional, Paiva, R. P., additional, Chouvarda, I., additional, Carvalho, P., additional, and Maglaveras, N., additional

Published
2017
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35. Reperfusion therapies and in-hospital outcomes for ST-elevation myocardial infarction in europe. the ACVC-EAPCI EORP STEMI registry of the european society of cardiology

Author

Zeymer, U., Ludman, P., Danchin, N., Kala, P., Laroche, C., Sadeghi, M., Caporale, R., Shaheen, S. M., Legutko, J., Iakobsishvili, Z., Alhabib, K. F., Motovska, Z., Studencan, M., Mimoso, J., Becker, D., Alexopoulos, D., Kereseselidze, Z., Stojkovic, S., Zelveian, P., Goda, A., Mirrakhimov, E., Bajraktari, G., Al-Farhan, H., Serpytis, P., Raungaard, B., Marandi, T., Moore, A. M., Quinn, M., Karjalainen, P. P., Tatu-Chitolu, G., Gale, C. P., Maggioni, A. P., Weidinger, F., Sinnaeve, P., Ferrari, R., Karamfilov, K., Lidon, R. -M., Kereselidze, Z., Iakobishvili, Z., Erglis, A., Kedev, S., Dudek, D., Tatu-Chitoiu, G., Shlyakhto, E., Bunc, M., Mourali, M. S., Konte, M., Larras, F., Lefrancq, E. F., Mekhaldi, S., Shuka, N., Pavli, E., Tafaj, E., Gishto, T., Dibra, A., Duka, A., Gjana, A., Kristo, A., Knuti, G., Demiraj, A., Dado, E., Hasimi, E., Simoni, L., Siqeca, M., Sisakian, H., Hayrapetyan, H., Markosyan, S., Galustyan, L., Arustamyan, N., Kzhdryan, H., Pepoyan, S., Zirkik, A., Von Lewinski, D., Paetzold, S., Kienzl, I., Matyas, K., Neunteufl, T., Nikfardjam, M., Neuhold, U., Mihalcz, A., Glaser, F., Steinwender, C., Reiter, C., Grund, M., Hrncic, D., Hoppe, U., Hammerer, M., Hinterbuchner, L., Hengstenberg, C., Delle Karth, G., Lang, I., Winkler, W., Hasun, M., Kastner, J., Havel, C., Derntl, M., Oberegger, G., Hajos, J., Adlbrecht, C., Publig, T., Leitgeb, M. -C., Wilfing, R., Jirak, P., C. -Y., Ho, Puskas, L., Schrutka, L., Spinar, J., Parenica, J., Hlinomaz, O., Fendrychova, V., Semenka, J., Sikora, J., Sitar, J., Groch, L., Rezek, M., Novak, M., Kramarikova, P., Stasek, J., Dusek, J., Zdrahal, P., Polasek, R., Karasek, J., Seiner, J., Sukova, N., Varvarovsky, I., Lazarak, T., Novotny, V., Matejka, J., Rokyta, R., Volovar, S., Belohlavek, J., Siranec, M., Kamenik, M., Kralik, R., Ravkilde, J., Jensen, S. E., Villadsen, A., Villefrance, K., Schmidt Skov, C., Maeng, M., Moeller, K., Hasan-Ali, H., Ahmed, T. A., Hassan, M., Elguindy, A., Farouk Ismail, M., Ibrahim Abd El-Aal, A., El-Sayed Gaafar, A., Magdy Hassan, H., Ahmed Shafie, M., Nabil El-Khouly, M., Bendary, A., Darwish, M., Ahmed, Y., Amin, O. A., Abdelhakim, A., Abosaif, K., Kandil, H., Galal, M. A. G., El Hefny, E. E., El Sayed, M., Aly, K., Mokarrab, M., Osman, M., Abdelhamid, M., Mantawy, S., Ali, M. R., Kaky, S. D., Khalil, V. A., Saraya, M. E. A., Talaat, A., Nabil, M., Mounir, W. M., Mahmoud, K., Aransa, A., Kazamel, G., Anwar, S., Al-Habbaa, A., Abd El Monem, M., Ismael, A., Amin Abu-Sheaishaa, M., Abd Rabou, M. M., Hammouda, T. M. A., Moaaz, M., Elkhashab, K., Ragab, T., Rashwan, A., Rmdan, A., Abdelrazek, G., Ebeid, H., Soliman Ghareeb, H., Farag, N., Zaki, M., Seleem, M., Torki, A., Youssef, M., Allah Nasser, N. A., Rafaat, A., Selim, H., Makram, M. M., Khayyal, M., Malasi, K., Madkour, A., Kolib, M., Alkady, H., Nagah, H., Yossef, M., Wafa, A., Mahfouz, E., Faheem, G., Magdy Moris, M., Ragab, A., Ghazal, M., Mabrouk, A., El-Masry, M., Naseem, M., Samir, S., Reinmets, J., Allvee, M., Saar, A., Ainla, T., Vaide, A., Kisseljova, M., Pakosta, U., Eha, J., Lotamois, K., Sia, J., Myllymaki, J., Pinola, T., Paana, T., Mikkelsson, J., Ampio, M., Tsivilasvili, J., Zurab, P., Agladze, R., Melia, A., Gogoberidze, D., Khubua, N., Totladze, L., Metreveli, I., Chikovani, A., Eitel, I., Poss, J., Werner, M., Constantz, A., Ahrens, C., Tolksdorf, H., Klinger, S., Sack, S., Heer, T., Lekakis, J., Kanakakis, I., Xenogiannis, I., Ermidou, K., Makris, N., Ntalianis, A., Katsaros, F., Revi, E., Kafkala, K., Mihelakis, E., Diakakis, G., Grammatikopoulos, K., Voutsinos, D., Xanthopoulou, I., Mplani, V., Foussas, S., Papakonstantinou, N., Patsourakos, N., Dimopoulos, A., Derventzis, A., Athanasiou, K., Vassilikos, V. P., Papadopoulos, C., Tzikas, S., Vogiatzis, I., Datsios, A., Galitsianos, I., Koutsampasopoulos, K., Grigoriadis, S., Douras, A., Baka, N., Spathis, S., Kyrlidis, T., Hatzinikolaou, H., Kiss, R. G., Nowotta, F., Toth, K., Szabo, S., Lakatos, C., Jambrik, Z., Ruzsa, J., Ruzsa, Z., Rona, S., Toth, J., Vargane Kosik, A., Toth, K. S. B., Nagy, G. G., Ondrejko, Z., Koromi, Z., Botos, B., Pourmoghadas, M., Salehi, A., Massoumi, G., Soleimani, A., Sarrafzadegan, N., Roohafza, H., Azarm, M., Mirmohammadsadeghi, A., Rajabi, D., Rahmani, Y., Siabani, S., Najafi, F., Hamzeh, B., Karim, H., Siabani, H., Saleh, N., Charehjoo, H., Zamzam, L., Al-Temimi, G., Al-Yassin, A., Mohammad, A., Ridha, A., Al-Saedi, G., Atabi, N., Sabbar, O., Mahmood, S., Dakhil, Z., Yaseen, I. F., Almyahi, M., Alkenzawi, H., Alkinani, T., Alyacopy, A., Kearney, P., Twomey, K., Shlomo, N., Beigel, R., Caldarola, P., Rutigliano, D., Sublimi Saponetti, L., Locuratolo, N., Palumbo, V., Scherillo, M., Formigli, D., Canova, P., Musumeci, G., Roncali, F., Metra, M., Lombardi, C., Visco, E., Rossi, L., Meloni, L., Montisci, R., Pippia, V., Marchetti, M. F., Congia, M., Cacace, C., Luca, G., Boscarelli, G., Indolfi, C., Ambrosio, G., Mongiardo, A., Spaccarotella, C., De Rosa, S., Canino, G., Critelli, C., Chiappetta, D., Battista, F., Gabrielli, D., Marziali, A., Bernabo, P., Navazio, A., Guerri, E., Manca, F., Gobbi, M., Oreto, Giuseppe, Andò, Giuseppe, Carerj, Scipione, Saporito, Francesco, Cimmino, Michele, Rigo, F., Zuin, G., Tuccillo, B., Scotto DI Uccio, F., Irace, L., Lorenzoni, G., Meloni, I., Merella, P., Polizzi, G. M., Pino, R., Marzilli, M., Morrone, D., Caravelli, P., Orsini, E., Mosa, S., Piovaccari, G., Santarelli, A., Cavazza, C., Romeo, F., Fedele, F., Mancone, M., Straito, M., Salvi, N., Scarparo, P., Severino, P., Razzini, C., Massaro, G., Cinque, A., Gaudio, C., Barilla, F., Torromeo, C., Porco, L., Mei, M., Iorio, R., Nassiacos, D., Barco, B., Sinagra, G., Falco, L., Priolo, L., Perkan, A., Strana, M., Percuku, L., Berisha, G., Mziu, B., Beishenkulov, M., Abdurashidova, T., Toktosunova, A., Kaliev, K., Serpytis, R., Butkute, E., Lizaitis, M., Broslavskyte, M., Xuereb, R. G., Mercieca Balbi, M., Paris, E., Buttigieg, L., Musial, W., Dobrzycki, S., Dubicki, A., Kazimierczyk, E., Tycinska, A., Wojakowski, W., Kalanska-Lukasik, B., Ochala, A., Wanha, W., Dworowy, S., Sielski, J., Janion, M., Janion-Sadowska, A., Wojtasik-Bakalarz, J., Bryniarski, L., Peruga, J. Z., Jonczyk, M., Jankowski, L., Klecha, A., Michalowska, J., Brzezinski, M., Kozmik, T., Kowalczyk, T., Adamczuk, J., Maliszewski, M., Kuziemka, P., Plaza, P., Jaros, A., Pawelec, A., Sledz, J., Bartus, S., Zmuda, W., Bogusz, M., Wisnicki, M., Szastak, G., Adamczyk, M., Suska, M., Czunko, P., Opolski, G., Kochman, J., Tomaniak, M., Miernik, S., Paczwa, K., Witkowski, A., Opolski, M. P., Staruch, A. D., Kalarus, Z., Honisz, G., Mencel, G., Swierad, M., Podolecki, T., Marques, J., Azevedo, P., Pereira, M. A., Gaspar, A., Monteiro, S., Goncalves, F., Leite, L., Manuel Lopes Dos Santos, W., Amado, J., Pereira, D., Silva, B., Caires, G., Neto, M., Rodrigues, R., Correia, A., Freitas, D., Lourenco, A., Ferreira, F., Sousa, F., Portugues, J., Calvo, L., Almeida, F., Alves, M., Silva, A., Caria, R., Seixo, F., Militaru, C., Ionica, E., Istratoaie, O., Florescu, M., Lipnitckaia, E., Osipova, O., Konstantinov, S., Bukatov, V., Vinokur, T., Egorova, E., Nefedova, E., Levashov, S., Gorbunova, A., Redkina, M., Karaulovskaya, N., Bijieva, F., Babich, N., Smirnova, O., Filyanin, R., Eseva, S., Kutluev, A., Chlopenova, A., Shtanko, A., Kuppar, E., Shaekhmurzina, E., Ibragimova, M., Mullahmetova, M., Chepisova, M., Kuzminykh, M., Betkaraeva, M., Namitokov, A., Khasanov, N., Baleeva, L., Galeeva, Z., Magamedkerimova, F., Ivantsov, E., Tavlueva, E., Kochergina, A., Sedykh, D., Kosmachova, E., Skibitskiy, V., Porodenko, N., Litovka, K., Ulbasheva, E., Niculina, S., Petrova, M., Harkov, E., Tsybulskaya, N., Lobanova, A., Chernova, A., Kuskaeva, A., Kuskaev, A., Ruda, M., Zateyshchikov, D., Gilarov, M., Konstantinova, E., Koroleva, O., Averkova, A., Zhukova, N., Kalimullin, D., Borovkova, N., Tokareva, A., Buyanova, M., Khaisheva, L., Pirozhenko, A., Novikova, T., Yakovlev, A., Tyurina, T., Lapshin, K., Moroshkina, N., Kiseleva, M., Fedorova, S., Krylova, L., Duplyakov, D., Semenova, Y., Rusina, A., Ryabov, V., Syrkina, A., Demianov, S., Reitblat, O., Artemchuk, A., Efremova, E., Makeeva, E., Menzorov, M., Shutov, A., Klimova, N., Shevchenko, I., Elistratova, O., Kostyuckova, O., Islamov, R., Budyak, V., Ponomareva, E., Ullah Jan, U., Alshehri, A. M., Sedky, E., Alsihati, Z., Mimish, L., Selem, A., Malik, A., Majeed, O., Altnji, I., Alshehri, M., Aref, A., Alhabib, K., Aldosary, M., Tayel, S., Abd Alrahman, M., Asfina, K. N., Abdin Hussein, G., Butt, M., Markovic Nikolic, N., Obradovic, S., Djenic, N., Brajovic, M., Davidovic, A., Romanovic, R., Novakovic, V., Dekleva, M., Spasic, M., Dzudovic, B., Jovic, Z., Cvijanovic, D., Veljkovic, S., Ivanov, I., Cankovic, M., Jarakovic, M., Kovacevic, M., Trajkovic, M., Mitov, V., Jovic, A., Hudec, M., Gombasky, M., Sumbal, J., Bohm, A., Baranova, E., Kovar, F., Samos, M., Podoba, J., Kurray, P., Obona, T., Remenarikova, A., Kollarik, B., Verebova, D., Kardosova, G., Alusik, D., Macakova, J., Kozlej, M., Bayes-Genis, A., Sionis, A., Garcia Garcia, C., Duran Cambra, A., Labata Salvador, C., Rueda Sobella, F., Sans Rosello, J., Vila Perales, M., Oliveras Vila, T., Ferrer Massot, M., Baneras, J., Lekuona, I., Zugazabeitia, G., Fernandez-Ortiz, A., Viana Tejedor, A., Ferrera, C., Alvarez, V., DIaz-Castro, O., Agra-Bermejo, R. M., Gonzalez-Cambeiro, C., Gonzalez-Babarro, E., Domingo-Del Valle, J., Royuela, N., Burgos, V., Canteli, A., Castrillo, C., Cobo, M., Ruiz, M., Abu-Assi, E., Garcia Acuna, J., Zeymer, U., Ludman, P., Danchin, N., Kala, P., Laroche, C., Sadeghi, M., Caporale, R., Shaheen, S. M., Legutko, J., Iakobsishvili, Z., Alhabib, K. F., Motovska, Z., Studencan, M., Mimoso, J., Becker, D., Alexopoulos, D., Kereseselidze, Z., Stojkovic, S., Zelveian, P., Goda, A., Mirrakhimov, E., Bajraktari, G., Al-Farhan, H., Serpytis, P., Raungaard, B., Marandi, T., Moore, A. M., Quinn, M., Karjalainen, P. P., Tatu-Chitolu, G., Gale, C. P., Maggioni, A. P., Weidinger, F., Sinnaeve, P., Ferrari, R., Karamfilov, K., Lidon, R. -M., Kereselidze, Z., Iakobishvili, Z., Erglis, A., Kedev, S., Dudek, D., Tatu-Chitoiu, G., Shlyakhto, E., Bunc, M., Mourali, M. S., Konte, M., Larras, F., Lefrancq, E. F., Mekhaldi, S., Shuka, N., Pavli, E., Tafaj, E., Gishto, T., Dibra, A., Duka, A., Gjana, A., Kristo, A., Knuti, G., Demiraj, A., Dado, E., Hasimi, E., Simoni, L., Siqeca, M., Sisakian, H., Hayrapetyan, H., Markosyan, S., Galustyan, L., Arustamyan, N., Kzhdryan, H., Pepoyan, S., Zirkik, A., Von Lewinski, D., Paetzold, S., Kienzl, I., Matyas, K., Neunteufl, T., Nikfardjam, M., Neuhold, U., Mihalcz, A., Glaser, F., Steinwender, C., Reiter, C., Grund, M., Hrncic, D., Hoppe, U., Hammerer, M., Hinterbuchner, L., Hengstenberg, C., Delle Karth, G., Lang, I., Winkler, W., Hasun, M., Kastner, J., Havel, C., Derntl, M., Oberegger, G., Hajos, J., Adlbrecht, C., Publig, T., Leitgeb, M. -C., Wilfing, R., Jirak, P., Ho, C. -Y., Puskas, L., Schrutka, L., Spinar, J., Parenica, J., Hlinomaz, O., Fendrychova, V., Semenka, J., Sikora, J., Sitar, J., Groch, L., Rezek, M., Novak, M., Kramarikova, P., Stasek, J., Dusek, J., Zdrahal, P., Polasek, R., Karasek, J., Seiner, J., Sukova, N., Varvarovsky, I., Lazarak, T., Novotny, V., Matejka, J., Rokyta, R., Volovar, S., Belohlavek, J., Siranec, M., Kamenik, M., Kralik, R., Ravkilde, J., Jensen, S. E., Villadsen, A., Villefrance, K., Schmidt Skov, C., Maeng, M., Moeller, K., Hasan-Ali, H., Ahmed, T. A., Hassan, M., Elguindy, A., Farouk Ismail, M., Ibrahim Abd El-Aal, A., El-Sayed Gaafar, A., Magdy Hassan, H., Ahmed Shafie, M., Nabil El-Khouly, M., Bendary, A., Darwish, M., Ahmed, Y., Amin, O. A., Abdelhakim, A., Abosaif, K., Kandil, H., Galal, M. A. G., El Hefny, E. E., El Sayed, M., Aly, K., Mokarrab, M., Osman, M., Abdelhamid, M., Mantawy, S., Ali, M. R., Kaky, S. D., Khalil, V. A., Saraya, M. E. A., Talaat, A., Nabil, M., Mounir, W. M., Mahmoud, K., Aransa, A., Kazamel, G., Anwar, S., Al-Habbaa, A., Abd El Monem, M., Ismael, A., Amin Abu-Sheaishaa, M., Abd Rabou, M. M., Hammouda, T. M. A., Moaaz, M., Elkhashab, K., Ragab, T., Rashwan, A., Rmdan, A., Abdelrazek, G., Ebeid, H., Soliman Ghareeb, H., Farag, N., Zaki, M., Seleem, M., Torki, A., Youssef, M., Allah Nasser, N. A., Rafaat, A., Selim, H., Makram, M. M., Khayyal, M., Malasi, K., Madkour, A., Kolib, M., Alkady, H., Nagah, H., Yossef, M., Wafa, A., Mahfouz, E., Faheem, G., Magdy Moris, M., Ragab, A., Ghazal, M., Mabrouk, A., El-Masry, M., Naseem, M., Samir, S., Reinmets, J., Allvee, M., Saar, A., Ainla, T., Vaide, A., Kisseljova, M., Pakosta, U., Eha, J., Lotamois, K., Sia, J., Myllymaki, J., Pinola, T., Paana, T., Mikkelsson, J., Ampio, M., Tsivilasvili, J., Zurab, P., Agladze, R., Melia, A., Gogoberidze, D., Khubua, N., Totladze, L., Metreveli, I., Chikovani, A., Eitel, I., Poss, J., Werner, M., Constantz, A., Ahrens, C., Tolksdorf, H., Klinger, S., Sack, S., Heer, T., Lekakis, J., Kanakakis, I., Xenogiannis, I., Ermidou, K., Makris, N., Ntalianis, A., Katsaros, F., Revi, E., Kafkala, K., Mihelakis, E., Diakakis, G., Grammatikopoulos, K., Voutsinos, D., Xanthopoulou, I., Mplani, V., Foussas, S., Papakonstantinou, N., Patsourakos, N., Dimopoulos, A., Derventzis, A., Athanasiou, K., Vassilikos, V. P., Papadopoulos, C., Tzikas, S., Vogiatzis, I., Datsios, A., Galitsianos, I., Koutsampasopoulos, K., Grigoriadis, S., Douras, A., Baka, N., Spathis, S., Kyrlidis, T., Hatzinikolaou, H., Kiss, R. G., Nowotta, F., Toth, K., Szabo, S., Lakatos, C., Jambrik, Z., Ruzsa, J., Ruzsa, Z., Rona, S., Toth, J., Vargane Kosik, A., Toth, K. S. B., Nagy, G. G., Ondrejko, Z., Koromi, Z., Botos, B., Pourmoghadas, M., Salehi, A., Massoumi, G., Soleimani, A., Sarrafzadegan, N., Roohafza, H., Azarm, M., Mirmohammadsadeghi, A., Rajabi, D., Rahmani, Y., Siabani, S., Najafi, F., Hamzeh, B., Karim, H., Siabani, H., Saleh, N., Charehjoo, H., Zamzam, L., Al-Temimi, G., Al-Yassin, A., Mohammad, A., Ridha, A., Al-Saedi, G., Atabi, N., Sabbar, O., Mahmood, S., Dakhil, Z., Yaseen, I. F., Almyahi, M., Alkenzawi, H., Alkinani, T., Alyacopy, A., Kearney, P., Twomey, K., Shlomo, N., Beigel, R., Caldarola, P., Rutigliano, D., Sublimi Saponetti, L., Locuratolo, N., Palumbo, V., Scherillo, M., Formigli, D., Canova, P., Musumeci, G., Roncali, F., Metra, M., Lombardi, C., Visco, E., Rossi, L., Meloni, L., Montisci, R., Pippia, V., Marchetti, M. F., Congia, M., Cacace, C., Luca, G., Boscarelli, G., Indolfi, C., Ambrosio, G., Mongiardo, A., Spaccarotella, C., De Rosa, S., Canino, G., Critelli, C., Chiappetta, D., Battista, F., Gabrielli, D., Marziali, A., Bernabo, P., Navazio, A., Guerri, E., Manca, F., Gobbi, M., Oreto, G., Ando, G., Carerj, S., Saporito, F., Cimmino, M., Rigo, F., Zuin, G., Tuccillo, B., Scotto DI Uccio, F., Irace, L., Lorenzoni, G., Meloni, I., Merella, P., Polizzi, G. M., Pino, R., Marzilli, M., Morrone, D., Caravelli, P., Orsini, E., Mosa, S., Piovaccari, G., Santarelli, A., Cavazza, C., Romeo, F., Fedele, F., Mancone, M., Straito, M., Salvi, N., Scarparo, P., Severino, P., Razzini, C., Massaro, G., Cinque, A., Gaudio, C., Barilla, F., Torromeo, C., Porco, L., Mei, M., Iorio, R., Nassiacos, D., Barco, B., Sinagra, G., Falco, L., Priolo, L., Perkan, A., Strana, M., Percuku, L., Berisha, G., Mziu, B., Beishenkulov, M., Abdurashidova, T., Toktosunova, A., Kaliev, K., Serpytis, R., Butkute, E., Lizaitis, M., Broslavskyte, M., Xuereb, R. G., Mercieca Balbi, M., Paris, E., Buttigieg, L., Musial, W., Dobrzycki, S., Dubicki, A., Kazimierczyk, E., Tycinska, A., Wojakowski, W., Kalanska-Lukasik, B., Ochala, A., Wanha, W., Dworowy, S., Sielski, J., Janion, M., Janion-Sadowska, A., Wojtasik-Bakalarz, J., Bryniarski, L., Peruga, J. Z., Jonczyk, M., Jankowski, L., Klecha, A., Michalowska, J., Brzezinski, M., Kozmik, T., Kowalczyk, T., Adamczuk, J., Maliszewski, M., Kuziemka, P., Plaza, P., Jaros, A., Pawelec, A., Sledz, J., Bartus, S., Zmuda, W., Bogusz, M., Wisnicki, M., Szastak, G., Adamczyk, M., Suska, M., Czunko, P., Opolski, G., Kochman, J., Tomaniak, M., Miernik, S., Paczwa, K., Witkowski, A., Opolski, M. P., Staruch, A. D., Kalarus, Z., Honisz, G., Mencel, G., Swierad, M., Podolecki, T., Marques, J., Azevedo, P., Pereira, M. A., Gaspar, A., Monteiro, S., Goncalves, F., Leite, L., Manuel Lopes Dos Santos, W., Amado, J., Pereira, D., Silva, B., Caires, G., Neto, M., Rodrigues, R., Correia, A., Freitas, D., Lourenco, A., Ferreira, F., Sousa, F., Portugues, J., Calvo, L., Almeida, F., Alves, M., Silva, A., Caria, R., Seixo, F., Militaru, C., Ionica, E., Istratoaie, O., Florescu, M., Lipnitckaia, E., Osipova, O., Konstantinov, S., Bukatov, V., Vinokur, T., Egorova, E., Nefedova, E., Levashov, S., Gorbunova, A., Redkina, M., Karaulovskaya, N., Bijieva, F., Babich, N., Smirnova, O., Filyanin, R., Eseva, S., Kutluev, A., Chlopenova, A., Shtanko, A., Kuppar, E., Shaekhmurzina, E., Ibragimova, M., Mullahmetova, M., Chepisova, M., Kuzminykh, M., Betkaraeva, M., Namitokov, A., Khasanov, N., Baleeva, L., Galeeva, Z., Magamedkerimova, F., Ivantsov, E., Tavlueva, E., Kochergina, A., Sedykh, D., Kosmachova, E., Skibitskiy, V., Porodenko, N., Litovka, K., Ulbasheva, E., Niculina, S., Petrova, M., Harkov, E., Tsybulskaya, N., Lobanova, A., Chernova, A., Kuskaeva, A., Kuskaev, A., Ruda, M., Zateyshchikov, D., Gilarov, M., Konstantinova, E., Koroleva, O., Averkova, A., Zhukova, N., Kalimullin, D., Borovkova, N., Tokareva, A., Buyanova, M., Khaisheva, L., Pirozhenko, A., Novikova, T., Yakovlev, A., Tyurina, T., Lapshin, K., Moroshkina, N., Kiseleva, M., Fedorova, S., Krylova, L., Duplyakov, D., Semenova, Y., Rusina, A., Ryabov, V., Syrkina, A., Demianov, S., Reitblat, O., Artemchuk, A., Efremova, E., Makeeva, E., Menzorov, M., Shutov, A., Klimova, N., Shevchenko, I., Elistratova, O., Kostyuckova, O., Islamov, R., Budyak, V., Ponomareva, E., Ullah Jan, U., Alshehri, A. M., Sedky, E., Alsihati, Z., Mimish, L., Selem, A., Malik, A., Majeed, O., Altnji, I., Alshehri, M., Aref, A., Alhabib, K., Aldosary, M., Tayel, S., Abd Alrahman, M., Asfina, K. N., Abdin Hussein, G., Butt, M., Markovic Nikolic, N., Obradovic, S., Djenic, N., Brajovic, M., Davidovic, A., Romanovic, R., Novakovic, V., Dekleva, M., Spasic, M., Dzudovic, B., Jovic, Z., Cvijanovic, D., Veljkovic, S., Ivanov, I., Cankovic, M., Jarakovic, M., Kovacevic, M., Trajkovic, M., Mitov, V., Jovic, A., Hudec, M., Gombasky, M., Sumbal, J., Bohm, A., Baranova, E., Kovar, F., Samos, M., Podoba, J., Kurray, P., Obona, T., Remenarikova, A., Kollarik, B., Verebova, D., Kardosova, G., Alusik, D., Macakova, J., Kozlej, M., Bayes-Genis, A., Sionis, A., Garcia Garcia, C., Duran Cambra, A., Labata Salvador, C., Rueda Sobella, F., Sans Rosello, J., Vila Perales, M., Oliveras Vila, T., Ferrer Massot, M., Baneras, J., Lekuona, I., Zugazabeitia, G., Fernandez-Ortiz, A., Viana Tejedor, A., Ferrera, C., Alvarez, V., DIaz-Castro, O., Agra-Bermejo, R. M., Gonzalez-Cambeiro, C., Gonzalez-Babarro, E., Domingo-Del Valle, J., Royuela, N., Burgos, V., Canteli, A., Castrillo, C., Cobo, M., Ruiz, M., Abu-Assi, E., and Garcia Acuna, J.

Subjects
Registrie, medicine.medical_specialty, medicine.medical_treatment, Cardiology, Myocardial Reperfusion, 030204 cardiovascular system & hematology, 03 medical and health sciences, Hospital, 0302 clinical medicine, Reperfusion therapy, Percutaneous Coronary Intervention, Internal medicine, Fibrinolysis, medicine, Humans, 030212 general & internal medicine, Myocardial infarction, Registries, Prospective Studies, Prospective cohort study, Observational studies, observational studies, reperfusion therapy, business.industry, Mortality rate, Primary percutaneous coronary intervention, ST-elevation myocardial infarction, Europe, Hospitals, Treatment Outcome, ST Elevation Myocardial Infarction, Percutaneous coronary intervention, medicine.disease, primary percutaneous coronary intervention, Observational studie, 3. Good health, Prospective Studie, Cohort, Conventional PCI, Cardiology and Cardiovascular Medicine, business, Human
Abstract

Aims The aim of this study was to determine the contemporary use of reperfusion therapy in the European Society of Cardiology (ESC) member and affiliated countries and adherence to ESC clinical practice guidelines in patients with ST-elevation myocardial infarction (STEMI). Methods and results Prospective cohort (EURObservational Research Programme STEMI Registry) of hospitalized STEMI patients with symptom onset Conclusions The use of reperfusion therapy for STEMI in the ESC member and affiliated countries was high. Primary PCI was the most frequently used treatment and associated total in-hospital mortality was below 5%. However, there was geographic variation in the use of primary PCI, which was associated with differences in in-hospital mortality.

Published
2021

38. Patrones de progresión de la actividad física en pacientes con EPOC

Author

Koreny, M, Demeyer, H, Benet, M, Arbillaga-Etxarri, A, Balcells, E, Barberan-Garcia, A, Gimeno-Santos, E, Hopkinson, NS, De Jong, C, Karlsson, N, Louvaris, Z, Polkey, MI, Puhan, MA, Rabinovich, RA, Rodríguez-Roisin, R, Vall-Casas, P, Vogiatzis, I, Troosters, T, Garcia-Aymerich, J, Urban Training Study Group and PROactive Consortium members, Urban Training Study Group, Delgado, A, Torrent-Pallicer, J, Vilaró, J, Chiaradía, DAR, Marín, A, Ortega, P, Celorrio, N, Teagudo, MM, Montellà, N, Muñoz, L, Toran, P, Simonet, P, Jané, C, Martín-Cantera, C, Borrell, E, PROactive Consortium members, Ivanoff, N, Corriol-Rohou, S, Jarrod, I, Erzen, D, Brindicci, C, Higenbottam, T, Scuri, M, McBride, P, Kamel, N, Tabberer, M, Dobbels, F, De Boer, P, Kulich, K, Glendenning, A, Rudell, K, Wilson, FJ, Nikai, E, Van der Molen, T, MacNee, B, Frei, A, Groningen Research Institute for Asthma and COPD (GRIAC), and EU/IMI Joint Undertaking

Subjects
Male, PROactive Consortium members, Respiratory System, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Medicine and Health Sciences, Pooled data, Determinants, COPD, biology, Patrones de progresión, General Medicine, Lama, Análisis de conglomerados, Respiratory Function Tests, MPOC, Female, EPOC, Determinantes, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Patrons de progressió, Physical activity, 616.2, 03 medical and health sciences, FEV1/FVC ratio, Cluster analysis, Multinomial logistic regression model, Internal medicine, Urban Training Study Group, medicine, Humans, Anàlisi de clústers, In patient, Exercise, Patterns of progression, business.industry, 1103 Clinical Sciences, medicine.disease, biology.organism_classification, C600, Urban Training Study Group and PROactive Consortium members, B900, Dyspnea, 030228 respiratory system, Usual care, Actividad física, Sedentary Behavior, Activitat física, business
Abstract

Introduction: Although mean physical activity in COPD patients declines by 400–500 steps/day annually, it is unknown whether the natural progression is the same for all patients. We aimed to identify distinct physical activity progression patterns using a hypothesis-free approach and to assess their determinants. Methods: We pooled data from two cohorts (usual care arm of Urban Training [NCT01897298] and PROactive initial validation [NCT01388218] studies) measuring physical activity at baseline and 12 months (Dynaport MoveMonitor). We identified clusters (patterns) of physical activity progression (based on levels and changes of steps/day) using k-means, and compared baseline sociodemographic, interpersonal, environmental, clinical and psychological characteristics across patterns. Results: In 291 COPD patients (mean ± SD 68 ± 8 years, 81% male, FEV1 59 ± 19%pred) we identified three distinct physical activity progression patterns: Inactive (n = 173 [59%], baseline: 4621 ± 1757 steps/day, 12-month change (Δ): −487 ± 1201 steps/day), Active Improvers (n = 49 [17%], baseline: 7727 ± 3275 steps/day, Δ: + 3378 ± 2203 steps/day) and Active Decliners (n = 69 [24%], baseline: 11 267 ± 3009 steps/day, Δ: −2217 ± 2085 steps/day). After adjustment in a mixed multinomial logistic regression model using Active Decliners as reference pattern, a lower 6-min walking distance (RRR [95% CI] 0.94 [0.90–0.98] per 10 m, P = .001) and a higher mMRC dyspnea score (1.71 [1.12–2.60] per 1 point, P = .012) were independently related with being Inactive. No baseline variable was independently associated with being an Active Improver. Conclusions: The natural progression in physical activity over time in COPD patients is heterogeneous. While Inactive patients relate to worse scores for clinical COPD characteristics, Active Improvers and Decliners cannot be predicted at baseline. Introducción: Aunque la actividad física en pacientes con EPOC declina una media anual de 400-500 pasos/día, se desconoce si esta progresión es igual en todos los pacientes. Este estudio pretendió identificar los patrones de progresión de la actividad física mediante métodos libres de hipótesis y evaluar sus determinantes. Métodos: Se estudiaron 291 pacientes con EPOC estable (media ± DE: 68 ± 8 años, 81% hombres, VEMS 59 ± 19%pred) de dos cohortes europeas con actividad física basal y a 12 meses (acelerómetro Dynaport MoveMonitor). Se identificaron conglomerados (patrones) de progresión de actividad física basados en los niveles y cambios de pasos/día usando k-means, y se compararon entre patrones las características sociodemográficas, interpersonales, ambientales, clínicas y psicosociales basales. Resultados: Se identificaron tres patrones: inactivo (n = 173 [59%], basal: 4.621 ± 1.757 pasos/día, cambio en 12 meses (Δ): −487 ± 1.201 pasos/día), activo que aumenta (n = 49 [17%], basal: 7.727 ± 3.275 pasos/día, Δ: +3.378 ± 2.203 pasos/día) y activo que reduce (n = 69 [24%], basal: 11.267 ± 3.009 pasos/día, Δ: −2.217 ± 2.085 pasos/día). La distancia en la prueba de la marcha de 6 minutos (6MWD) y la disnea se asociaron independientemente con ser inactivo: RRR [IC 95%] 0,94 [0,90-0,98] por cada 10 m de 6MWD (p = 0,001) y 1,71 [1,12-2,60] por cada punto en la escala mMRC (p = 0,012), respectivamente, en comparación con el patrón activo que reduce. No se encontraron variables basales independientemente asociadas con ser activo que aumenta. Conclusiones: La progresión natural de la actividad física en pacientes con EPOC es heterogénea. Mientras que el patrón de pacientes inactivo se relaciona con peores características clínicas de EPOC, no se pudo predecir la evolución de los activos a aumentar o reducir. info:eu-repo/semantics/acceptedVersion

Published
2021

41. Patterns of Physical Activity Progression in Patients With COPD [Patrones de progresión de la actividad física en pacientes con EPOC]

Author

Koreny, M. Demeyer, H. Benet, M. Arbillaga-Etxarri, A. Balcells, E. Barberan-Garcia, A. Gimeno-Santos, E. Hopkinson, N.S. De Jong, C. Karlsson, N. Louvaris, Z. Polkey, M.I. Puhan, M.A. Rabinovich, R.A. Rodríguez-Roisin, R. Vall-Casas, P. Vogiatzis, I. Troosters, T. Garcia-Aymerich, J. Delgado, A. Torrent-Pallicer, J. Vilaró, J. Rodriguez-Roisín, R. Chiaradía, D.A.R. Marín, A. Ortega, P. Celorrio, N. Monteagudo, M. Montellà, N. Muñoz, L. Toran, P. Simonet, P. Jané, C. Martín-Cantera, C. Borrell, E. Ivanoff, N. Corriol-Rohou, S. Jarrod, I. Erzen, D. Brindicci, C. Higenbottam, T. Scuri, M. McBride, P. Kamel, N. Tabberer, M. Dobbels, F. de Boer, P. Kulich, K. Glendenning, A. Rudell, K. Wilson, F.J. Hopkinson, N.S. Nikai, E. van der Molen, T. MacNee, B. Frei, A. The Urban Training Study Group PROactive Consortium members The Urban Training Study Group The PROactive Consortium members

Abstract

Introduction: Although mean physical activity in COPD patients declines by 400–500 steps/day annually, it is unknown whether the natural progression is the same for all patients. We aimed to identify distinct physical activity progression patterns using a hypothesis-free approach and to assess their determinants. Methods: We pooled data from two cohorts (usual care arm of Urban Training [NCT01897298] and PROactive initial validation [NCT01388218] studies) measuring physical activity at baseline and 12 months (Dynaport MoveMonitor). We identified clusters (patterns) of physical activity progression (based on levels and changes of steps/day) using k-means, and compared baseline sociodemographic, interpersonal, environmental, clinical and psychological characteristics across patterns. Results: In 291 COPD patients (mean ± SD 68 ± 8 years, 81% male, FEV1 59 ± 19%pred) we identified three distinct physical activity progression patterns: Inactive (n = 173 [59%], baseline: 4621 ± 1757 steps/day, 12-month change (Δ): −487 ± 1201 steps/day), Active Improvers (n = 49 [17%], baseline: 7727 ± 3275 steps/day, Δ: + 3378 ± 2203 steps/day) and Active Decliners (n = 69 [24%], baseline: 11 267 ± 3009 steps/day, Δ: −2217 ± 2085 steps/day). After adjustment in a mixed multinomial logistic regression model using Active Decliners as reference pattern, a lower 6-min walking distance (RRR [95% CI] 0.94 [0.90–0.98] per 10 m, P =.001) and a higher mMRC dyspnea score (1.71 [1.12–2.60] per 1 point, P =.012) were independently related with being Inactive. No baseline variable was independently associated with being an Active Improver. Conclusions: The natural progression in physical activity over time in COPD patients is heterogeneous. While Inactive patients relate to worse scores for clinical COPD characteristics, Active Improvers and Decliners cannot be predicted at baseline. © 2020 SEPAR

Published
2021

42. Validity and responsiveness of the Daily-and Clinical visit-PROactive Physical Activity in COPD (D-PPAC and C-PPAC) instruments

Author

Garcia-Aymerich, J. Puhan, M.A. Corriol-Rohou, S. De Jong, C. Demeyer, H. Dobbels, F. Erzen, D. Frei, A. Gimeno-Santos, E. Hopkinson, N.S. Ivanoff, N. Karlsson, N. Louvaris, Z. Polkey, M.I. Rabinovich, R.A. Scuri, M. Tabberer, M. Vogiatzis, I. Troosters, T.

Abstract

Background The Daily-PROactive and Clinical visit-PROactive Physical Activity (D-PPAC and C-PPAC) instruments in chronic obstructive pulmonary disease (COPD) combines questionnaire with activity monitor data to measure patients' experience of physical activity. Their amount, difficulty and total scores range from 0 (worst) to 100 (best) but require further psychometric evaluation. Objective To test reliability, validity and responsiveness, and to define minimal important difference (MID), of the D-PPAC and C-PPAC instruments, in a large population of patients with stable COPD from diverse severities, settings and countries. Methods We used data from seven randomised controlled trials to evaluate D-PPAC and C-PPAC internal consistency and construct validity by sex, age groups, COPD severity, country and language as well as responsiveness to interventions, ability to detect change and MID. Results We included 1324 patients (mean (SD) age 66 (8) years, forced expiratory volume in 1 s 55 (17)% predicted). Scores covered almost the full range from 0 to 100, showed strong internal consistency after stratification and correlated as a priori hypothesised with dyspnoea, health-related quality of life and exercise capacity. Difficulty scores improved after pharmacological treatment and pulmonary rehabilitation, while amount scores improved after behavioural physical activity interventions. All scores were responsive to changes in self-reported physical activity experience (both worsening and improvement) and to the occurrence of COPD exacerbations during follow-up. The MID was estimated to 6 for amount and difficulty scores and 4 for total score. Conclusions The D-PPAC and C-PPAC instruments are reliable and valid across diverse COPD populations and responsive to pharmacological and non-pharmacological interventions and changes in clinically relevant variables. © Author(s) (or their employer(s)) 2021.

Published
2021

44. Interval versus constant-load exercise training in adults with Cystic Fibrosis

Author

Kaltsakas, G. Chynkiamis, N. Anastasopoulos, N. Zeliou, P. Karapatoucha, V. Kotsifas, K. Diamantea, F. Inglezos, I. Koulouris, N.G. Vogiatzis, I.

Subjects
fungi
Abstract

Background: The efficacy of interval exercise (IE) compared to constant-load exercise (CLE) training remains unsettled in adults with Cystic Fibrosis (CF). Methods: Twenty-four adults with CF were randomised to 30-min IE (100 % peak work capacity (WRpeak) for 30-s alternated with 40 % WRpeak for 30-s; n = 12) or 30-min CLE (70 % WRpeak; n = 12) training, 3 times weekly, for 12 weeks. Isometric quadriceps muscle strength was assessed using a strain gauge Myometer. Results: The magnitude of improvement in quadriceps muscle strength was greater (p = 0.037) in the IE (by 32 ± 13 Nm) compared to the CLE (by 23 ± 12 Nm) groups. Maximum inspiratory and expiratory mouth pressures were significantly improved only in the IE group (by 30 ± 10 cmH2O; p = 0.009 and 13 ± 4 cmH2O; p = 0.007, respectively). Arterial oxygen saturation during training was higher (p = 0.002) for IE (94 ± 1%) compared to CLE (91 ± 1%), whereas dyspnoea scores were lower (p = 0.001) for IE (3.8 ± 0.7) compared to CLE (5.9 ± 0.8) Conclusions: IE is superior to CLE in improving peripheral and respiratory muscle strength and preferable to CLE because it is associated with lower exercise-induced arterial oxygen desaturation and breathlessness. © 2021 Elsevier B.V.

Published
2021

46. Electronic medical registry of acute coronary syndromes in Greece. (ILIAKTIS study): Rationale and study design

Author

Kanakakis, Ioannis, primary, Stafylas, Panagiotis, additional, Avramidis, Dimitrios, additional, Dagre, Anna, additional, Latsios, George, additional, Nikas, Dimitris, additional, Patsourakos, Nikos, additional, Pipilis, Athanasios, additional, Sanidas, Ilias, additional, Skalidis, Emmanouil, additional, Synetos, Andreas, additional, Tziakas, Dimitrios, additional, Tzikas, Stergios, additional, Tsiafoutis, Ioannis, additional, Tsigkas, Grigoris, additional, Bamidis, Panagiotis, additional, Kanakakis, I., additional, Tselegkidi, M.E., additional, Sertedaki, E., additional, marelis, I., additional, Fragkos, E., additional, Mantzouranis, E., additional, Karvounis, C., additional, Zafeiropoulos, S., additional, Manolis, A.J., additional, Chatzilymperis, G., additional, Chiotelis, I., additional, Gryllis, D., additional, Poulimenos, L.E., additional, Triantafyllis, A., additional, Alexopoulos, D., additional, Varlamos, C., additional, Almpanis, G., additional, Aggeli, A., additional, Sakkas, A., additional, Trikas, A., additional, Tsiamis, S., additional, Triantafylloy, K., additional, Mpenia, D., additional, Oikonomou, D., additional, Papadopoulou, E., additional, Avramidis, D., additional, Kousta, M., additional, Moulianitaki, E., additional, Poulianitis, G., additional, Mavrou, G., additional, Latsios, G., additional, Synetos, A., additional, Tousoulis, D., additional, Kafkas, N., additional, Godwin, S., additional, Mertzanos, G., additional, Koytouzis, M., additional, Tsiafoutis, I., additional, Papadopoulos, A., additional, Tsoumeleas, A., additional, Barbetseas, I., additional, Sanidas, I., additional, Athanasiou, A., additional, Paizis, I., additional, Kakkavas, A., additional, Papafanis, T., additional, Mantas, I., additional, Neroutsos, G., additional, Gkoliopoulou, A., additional, Tafrali, V., additional, Florou, N., additional, Diakakis, G., additional, Grammatikopoulos, K., additional, Sinanis, T., additional, Kartalis, A., additional, Afendoulis, D., additional, Voutas, P., additional, Kardamis, C., additional, Doulis, A., additional, Kalantzis, N., additional, Vergis, K., additional, Chasikidis, C., additional, Armatas, G., additional, Damelou, A., additional, Ntogka, M., additional, Serafetinidis, I., additional, Zagkas, K., additional, Tselempis, T., additional, Makridis, P., additional, Karantoumanis, I., additional, Karapatsoudi, E., additional, Oikonomou, K., additional, Foukarakis, E., additional, Kafarakis, P., additional, Pitarokoilis, M., additional, Rogdakis, E., additional, Stavrakis, S., additional, Koudounis, G., additional, Karampetsos, V., additional, Lionakis, N., additional, Panotopoulos, C., additional, Svoronos, D., additional, Tsorlalis, I., additional, Tsatiris, K., additional, Beneki, E., additional, Papadopoulos, N., additional, Sawafta, A., additional, Kozatsani, D., additional, Spyromitros, G., additional, Bostanitis, I., additional, Dimitriadis, G., additional, Nikoloulis, N., additional, Kampouridis, N., additional, Giampatzis, V., additional, Patsilinakos, S., additional, Andrikou, E., additional, Katsiadas, N., additional, Papanagnou, G., additional, Kotsakis, A., additional, Ioannidis, E., additional, Platogiannis, N., additional, Psychari, S., additional, Pissimissis, E., additional, Patsourakos, N., additional, Gavrielatos, G., additional, Maritsa, D., additional, Papakonstantinou, N., additional, Oikonomou, G., additional, Katsanou, K., additional, Lazaris, E., additional, Moschos, N., additional, Giakoumakis, T., additional, Papagiannis, N., additional, Goudis, C., additional, Daios, S., additional, Devliotis, K., additional, Dimitriadis, F., additional, Giannadaki, M., additional, Savvidis, M., additional, Tsinopoulos, G., additional, Zarifis, I., additional, Askalidou, T., additional, Vasileiadis, I., additional, Kleitsiotou, P., additional, Sidiropoulos, S., additional, Tsaousidis, A., additional, Tzikas, S., additional, Vassilikos, V., additional, Papadopoulos, C., additional, Zarvalis, E., additional, Gogos, C., additional, Moschovidis, V., additional, Styliadis, I., additional, Laschos, V., additional, Spathoulas, K., additional, Vogiatzis, I., additional, Kasmeridis, C., additional, Pittas, S., additional, Sdogkos, E., additional, Dagre, A., additional, Mpounas, P., additional, Rodis, I., additional, Pipilis, A., additional, Konstantinidis, S., additional, Makrygiannis, S., additional, Masdrakis, A., additional, Magginas, A., additional, Sevastos, G., additional, Katsimagklis, G., additional, Mastrokostopoulos, A., additional, Papaioannou, S., additional, Skalidis, E., additional, Petousis, S., additional, Davlouros, P., additional, Tsigkas, G., additional, Hahalis, G., additional, Koufou, E., additional, Tziakas, D., additional, Chalikias, G., additional, Thomaidi, A., additional, Stakos, D., additional, Chotidis, A., additional, Nikas, D., additional, Sakellariou, X., additional, Skoularigkis, I., additional, Dimos, A., additional, Iakovis, N., additional, Mpourazana, A., additional, Zagouras, A., additional, Ntalas, I., additional, Theodoridou, S., additional, Papagoras, G., additional, Tsoumis, C., additional, Pappa, E., additional, Kotsia, A., additional, Toli, E., additional, Mantzoukis, S., additional, Revi, E., additional, Stafylas, P., additional, Karaiskou, M., additional, Bamidis, P., additional, Lagakis, P., additional, Spachos, D., additional, and Lygkouri, G., additional

Published
2021
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48. Greater exercise tolerance in COPD during acute interval, compared to equivalent constant-load, cycle exercise: physiological mechanisms

Author

Louvaris, Z. Chynkiamis, N. Spetsioti, S. Asimakos, A. Zakynthinos, S. Wagner, P.D. Vogiatzis, I.

Abstract

Key points: Exercise intolerance is common in chronic obstructive pulmonary disease (COPD) patients. In patients with COPD, we compared an interval exercise (IE) protocol (alternating 30 s at 100% peak work rate (WRpeak) with 30 s at 50% WRpeak) with moderate-intensity constant-load exercise (CLE) at 75% WRpeak, which yielded the same work rate. Exercise endurance time and total work output were almost twice as high for IE than CLE. At exercise isotime (when work completed was the same between IE and CLE), IE was associated with less dynamic hyperinflation, lower blood lactate concentration, and greater respiratory and locomotor muscle oxygenation, but there were no differences in ventilation or cardiac output. However, at the limit of tolerance for each modality, dynamic hyperinflation was not different between IE and CLE, while blood lactate remained lower and muscle oxygenation higher with IE. Taken together, these findings suggest that dynamic hyperinflation and not muscle-based factors dictate the limits of tolerance in these COPD patients. Abstract: The relative importance of ventilatory, circulatory and peripheral muscle factors in determining tolerance to exercise in patients with chronic obstructive pulmonary disease (COPD) is not known. In 12 COPD patients (forced expiratory volume in one second: 58 ± 17%pred.) we measured ventilation, cardiac output, dynamic hyperinflation, local muscle oxygenation, blood lactate and time to exhaustion during (a) interval exercise (IE) consisting of 30 s at 100% peak work rate alternating with 30 s at 50%, and (b) constant-load exercise (CLE) at 75% peak work rate, designed to produce the same average work rate. Exercise time was substantially longer during IE than CLE (19.5 ± 4.8 versus 11.4 ± 2.1 min, p = 0.0001). Total work output was therefore greater during IE than CLE (81.3 ± 27.7 versus 48.9 ± 23.8 kJ, p = 0.0001). Dynamic hyperinflation (assessed by changes from baseline in inspiratory capacity, ΔIC) was less during IE than CLE at CLE exhaustion time (isotime, p = 0.009), but was similar at exhaustion (ΔICCLE: -0.38 ± 0.10 versus ΔICIE: -0.33 ± 0.12 l, p = 0.102). In contrast, at isotime, minute ventilation, cardiac output and systemic oxygen delivery did not differ between protocols (P > 0.05). At exhaustion in both protocols, the vastus lateralis and intercostal muscle oxygen saturation were higher in IE than CLE (p = 0.014 and p = 0.0002, respectively) and blood lactate concentrations were lower (4.9 ± 2.4 mmol l-1 versus 6.4 ± 2.2 mmol l-1, p = 0.039). These results suggest that (1) exercise tolerance with COPD is limited by dynamic hyperinflation; and (2) cyclically lower (50%) effort intervals in IE help to preserve muscle oxygenation and reduce metabolic acidosis compared with CLE at the same average work rate; but these factors do not appear to determine time to exhaustion. © 2020 The Authors. The Journal of Physiology © 2020 The Physiological Society

Published
2020

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