1. Diffuse Neonatal Hemangiomatosis: report of 5 cases.
- Author
-
Wananukul S, Voramethkul W, Nuchprayoon I, and Seksarn P
- Subjects
- Angiomatosis complications, Female, Hemangioma complications, Humans, Infant, Infant, Newborn, Liver Neoplasms complications, Male, Skin Neoplasms complications, Angiomatosis diagnosis, Angiomatosis drug therapy, Antineoplastic Agents, Hormonal therapeutic use, Antineoplastic Agents, Phytogenic therapeutic use, Hemangioma diagnosis, Hemangioma drug therapy, Liver Neoplasms diagnosis, Liver Neoplasms drug therapy, Prednisolone therapeutic use, Skin Neoplasms diagnosis, Skin Neoplasms drug therapy, Vinblastine therapeutic use
- Abstract
Diffuse Neonatal Hemangiomatosis (DNH) is a rare, life-threatening condition associated with a few to hundreds of small, cutaneous and visceral hemangiomas. The authors reported 5 cases of DNH in which hepatic hemangioma were the most common visceral involvement. Response to prednisolone in these cases was not good, one died and four required second line therapy. Of these four cases, one case with embolisation; one with interferon and two with vinblastine. Response to vinblastine was good, but long-term follow-up of the side effects are needed.
- Published
- 2006