195 results on '"Vosberg, Sebastian"'
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2. In vivo PDX CRISPR/Cas9 screens reveal mutual therapeutic targets to overcome heterogeneous acquired chemo-resistance
3. Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes
4. Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer
5. A clinically applicable gene expression–based score predicts resistance to induction treatment in acute myeloid leukemia
6. The clinical mutatome of core binding factor leukemia
7. Loss of KDM6A confers drug resistance in acute myeloid leukemia
8. PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
9. In-depth mutational analyses of colorectal neuroendocrine carcinomas with adenoma or adenocarcinoma components
10. Supplementary Figures from Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
11. Table S4 from Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
12. Elevated RIPK3 correlates with disease burden in myelofibrosis
13. Acute Myeloid Leukemia with Isolated Trisomy 4 Is Characterized By Frequent Mutations of TET2 and a Distinct DNA Methylation Signature
14. Prevalence, Clinical and Molecular Features, and Prognostic Value of Tetraploidy/Near-Tetraploidy in Patients with Acute Myeloid Leukemia
15. An Inducible Leukemia-Associated Transcription Factor Facilitates Large-Scale Ex Vivo Generation of Functional Human Macrophages
16. Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism
17. Fusion gene detection by RNA-sequencing complements diagnostics of acute myeloid leukemia and identifies recurring NRIP1-MIR99AHG rearrangements
18. Mutations inHID1Cause Syndromic Infantile Encephalopathy and Hypopituitarism
19. DNA methylation epitypes highlight underlying developmental and disease pathways in acute myeloid leukemia
20. Molecular Subgroups of T Cell Acute Lymphoblastic Leukemia in Adults Treated According to GMALL Protocols
21. Gene Fusion Detection By RNA-Seq in Acute Myeloid Leukemia (AML)
22. DNA Methylation Profiling of AML Reveals Epigenetic Subgroups with Distinct Clinical Outcome
23. Clonal evolution of acute myeloid leukemia from diagnosis to relapse
24. Loss of KDM6A confers drug resistance in acute myeloid leukemia
25. Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)
26. Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia
27. Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load
28. Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients
29. Evolutionary Patterns of Cytogenetically Normal Acute Myeloid Leukemia Correlate with Time to Relapse
30. Clones with and without Sensitivity Towards Treatment In Vivo Co-Exist within the Tumor Cells of a Single Patient with ALL
31. Comparison of FLT3-ITD Detection By High-Throughput Amplicon Sequencing to Routine Diagnostics - a Retrospective Analysis of AMLCG Study Patients
32. Acute myeloid leukemia with del(9q) is characterized by frequent mutations ofNPM1,DNMT3A, WT1and low expression ofTLE4
33. DDX41-Low Expression Mimics Germline DDX41-Phenotype in Acute Myeloid Leukemia
34. Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations
35. ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
36. Close correlation of copy number aberrations detected by next-generation sequencing with results from routine cytogenetics in acute myeloid leukemia
37. Genomic Profiling Reveals Gain of Mutations in Histone Methylation Regulators in Relapsed Adult B Cell Precursor ALL
38. Molecular Alterations in Refractory Acute Myeloid Leukemia and Persistent Preleukemic Lesions Are Disclosed Using Mesenchymal Stromal Cells As Germline Control
39. Detection of Chromosomal Aberrations in Acute Myeloid Leukemia By Copy Number Alteration Analysis of Exome Sequencing Data
40. Functional Diversity of Single Stem Cell Clones in Patients' Acute Lymphoblastic Leukemia Growing in Mice: An Adverse Subclone with Distinct DNA-Methylation Pattern, Slow Growth In Vivo and Drug Resistance
41. Acute Myeloid Leukemia in the Elderly Is Characterized By a Distinct Genetic Landscape
42. Mutations of Genes Linked to Epigenetic Regulation Are Frequently Gained in Relapsed Cytogenetically Normal Acute Myeloid Leukemia
43. PAX5biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
44. Characterization of the immune microenvironment in matched primary and metastatic breast cancer lesions from the AURORA study: BIG 14-01.
45. Multi-Omics of Adult T Cell Acute Lymphoblastic Leukemia
46. Homocygous PAX5Sequence Mutations Define a Novel Subtype of B Cell Precursor Acute Lymphoblastic Leukemia
47. Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation
48. The Mutatome of CBFB/MYH11-rearranged Acute Myeloid Leukemia (AML)
49. Analysis of the Tissue-Specific Expression Requirements and Identification of Cooperating Mutations for Leukemogenesis in an Inducible CALM/AF10 Knock-in Mouse Model
50. Copy Number Alteration (CNA) Analysis in Targeted Sequencing Data from Acute Myeloid Leukemia (AML) Patients with Chromosome 9q Deletion
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