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19. A novel approach to the quantification of aortic root in vivo structural mechanics

Author

Votta, E, Presicce, M., Dellegrottaglie, S., Bancone, C., Sturla, F., Redaelli, A., DELLA CORTE, Alessandro, Votta, E, Presicce, M., DELLA CORTE, Alessandro, Dellegrottaglie, S., Bancone, C., Sturla, F., and Redaelli, A.

Subjects
Adult, Male, Applied Mathematics, Finite Element Analysis, In vivo biomechanics, Models, Cardiovascular, Biomedical Engineering, Biomechanical Phenomena, Magnetic resonance imaging, Computational Theory and Mathematics, In vivo biomechanic, Computational Theory and Mathematic, Aortic root, Aortic valve, Finite element modeling, Software, Modeling and Simulation, Molecular Biology, cardiovascular system, Humans, Female, Aorta
Abstract

Understanding aortic root in vivo biomechanics can help in elucidating key mechanisms involved in aortic root pathologies and in the outcome of their surgical treatment. Numerical models can provide useful quantitative information. For this to be reliable, detailed aortic root anatomy should be captured. Also, since the aortic root is never unloaded throughout the cardiac cycle, the modeled geometry should be consistent with the in vivo loads acting on it. Achieving such consistency is still a challenge, which was tackled only by few numerical studies. Here we propose and describe in detail a new approach to the finite element modeling of aortic root in vivo structural mechanics. Our approach exploits the anatomical information yielded by magnetic resonance imaging by reconstructing the 3-dimensional end-diastolic geometry of the aortic root and makes the reconstructed geometry consistent with end-diastolic loading conditions through the estimation of the corresponding prestresses field. We implemented our approach through a semiautomated modeling pipeline, and we applied it to quantify aortic root biomechanics in 4 healthy participants. Computed results highlighted that including prestresses into the model allowed for pressurizing the aortic root to the end-diastolic pressure while matching the image-based ground truth data. Aortic root dynamics, tissues strains, and stresses computed at relevant time points through the cardiac cycle were consistent with a broad set of data from previous computational and in vivo studies, strongly suggesting the potential of the method. Also, results highlighted the major role played by the anatomy in driving aortic root biomechanics.

Published
2017

20. Thrombogenic Potential Of Altered Hemodynamics At The Left Ventricular Apex-LVAD Cannula Interface: A Numerical Study

Author

Apostoli, A., Bianchi, V., Selmi, M., Votta, E., Melisurgo, G., Slepian, M. J., Redaelli, A., PAPPALARDO, FEDERICO, CONSOLO, FILIPPO, Apostoli, A., Bianchi, V., Selmi, M., Votta, E., Melisurgo, G., Pappalardo, Federico, Slepian, M. J., Redaelli, A., and Consolo, Filippo

Abstract

Study: Left Ventricular Assist Device (LVAD) support, despite affording increased survival for patients with advanced systolic heart failure (HF), remains limited by post-implant pump thrombosis. Thrombus formation has been observed to occur at the Left Ventricle (LV) apex-LVAD inflow cannula interface, where altered hemodynamics is characterized by low Wall Shear Stress (WSS), which may trigger an activated prothrombotic phenotype of endothelial cells (ECs) with associated platelet activation, adherence and progressive thrombosis. We present a computational method to compute LV hemodynamics and WSS distribution over consecutive cardiac cycles for both healthy and failing LVs, to evaluate the associated thrombogenic potential. Methods: Patient specific LV geometrical models were reconstructed from 3D TT-ECHO as follows: a) healthy, with ejection volume (EV) of 70 ml; b) failing HF with residual 50% EV (35 ml); c) failing HF with no residual EV + LVAD inflow cannula. Dynamics of the cardiac cycle were simulated in ANSYS Fluent. The LV wall motion was set through mesh motion User Defined Functions, allowing to model contraction and twist during systole, expansion and untwist during diastole (Fig1A) Results: WSS in the apical region was one order of magnitude greater for the healthy LV compared to that of the HF LVs (with/without LVAD, Fig1B), demonstrating that reducing the LV contractility results in reduced WSS. The HF LV + LVAD model revealed a further decrease in WSS (Fig1B). In addition, the presence of the cannula largely altered the LV apex hemodynamics: the velocity magnitude was < 0.1 m/s, revealing the presence of a region of stagnation - i.e. a critical prothrombotic condition. Hemodynamics in the LVAD-implanted LV showed the highest thrombogenic potential, consistent with clinical observations. Our model provides mechanistic insights into the thrombogenic risk of LVAD patients and the significance of the LV apex-LVAD interface as a nidus of thrombosis

Published
2017

27. Insights on the echocardiographically normally functioning bicuspid aortic valve and root from a morphofunctional magnetic resonance imaging study. Valves in the Heart of the Big Apple VI: evaluation and management of valvular heart diseases 2010

Author

DELLA CORTE, Alessandro, DEL VISCOVO, Luca, Bancone C, Conti CA, Votta E, Mastroianni C, Citarella A, DE FEO, Marisa, Redaelli A, NAPPI, Gianantonio, DELLA CORTE, Alessandro, DEL VISCOVO, Luca, Bancone, C, Conti, Ca, Votta, E, Mastroianni, C, Citarella, A, DE FEO, Marisa, Redaelli, A, and Nappi, Gianantonio

Published
2010

35. Multiscale Mechanical Model of Microtubule

Author

Marco Agostino Deriu, Enemark, S., Votta, E., Soncini, Monica, Redaelli, Alberto Cesare Luigi, and Montevecchi, Franco Maria

Subjects
Multiscale, Tubulin, Mechanics
Published
2008

39. A novel approach to the quantification of aortic root in vivo structural mechanics.

Author

Votta, E., Presicce, M., Della Corte, A., Dellegrottaglie, S., Bancone, C., Sturla, F., and Redaelli, A.

Subjects
*AORTIC valve, *BIOMECHANICS, *DIASTOLE (Cardiac cycle), *FINITE element method, *IN vivo studies
Abstract

Understanding aortic root in vivo biomechanics can help in elucidating key mechanisms involved in aortic root pathologies and in the outcome of their surgical treatment. Numerical models can provide useful quantitative information. For this to be reliable, detailed aortic root anatomy should be captured. Also, since the aortic root is never unloaded throughout the cardiac cycle, the modeled geometry should be consistent with the in vivo loads acting on it. Achieving such consistency is still a challenge, which was tackled only by few numerical studies. Here we propose and describe in detail a new approach to the finite element modeling of aortic root in vivo structural mechanics. Our approach exploits the anatomical information yielded by magnetic resonance imaging by reconstructing the 3-dimensional end-diastolic geometry of the aortic root and makes the reconstructed geometry consistent with end-diastolic loading conditions through the estimation of the corresponding prestresses field. We implemented our approach through a semiautomated modeling pipeline, and we applied it to quantify aortic root biomechanics in 4 healthy participants. Computed results highlighted that including prestresses into the model allowed for pressurizing the aortic root to the end-diastolic pressure while matching the image-based ground truth data. Aortic root dynamics, tissues strains, and stresses computed at relevant time points through the cardiac cycle were consistent with a broad set of data from previous computational and in vivo studies, strongly suggesting the potential of the method. Also, results highlighted the major role played by the anatomy in driving aortic root biomechanics. [ABSTRACT FROM AUTHOR]

Published
2017
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40. QUANTIFICATION OF ANATOMICAL AND FLUID-DYNAMIC ANOMALIES IN FONTAN PATIENTS BASED ON MAGNETIC RESONANCE IMAGING.

Author

Signorini, G., Tirelli, S., Piatti, F., Pluchinotta, F., Siryk, S., Votta, E., Lombardi, M., and Redaelli, A.

Abstract

Copyright of Naukovi visti NTUU - KPI is the property of National Technical University of Ukraine KPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017
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43. A web of connections

Author

Lee, B, Braitman, S, Campbell, B, Chirop, A, Edwards, Nancy, Eldred, S, Hamel, N, Holdway, K, Kothari, Anita, Mill, J, Sheppard-Lemoine, D, and Votta, E

Subjects
Health Policy, Community Health and Preventive Medicine, Public Health, Health Services Administration
Published
2004

45. These abstracts have been selected for VIEWING only as ePosters and in print. ePosters will be available on Screen A & B throughout the meeting, Print Posters at the times indicated below. Please refer to the PROGRAM for more details.

Author

Secchi, F., primary, Cannao, P., additional, Pluchinotta, F., additional, Butera, G., additional, Carminati, M., additional, Sardanelli, F., additional, Lombardi, M., additional, Monney, P., additional, Piccini, D., additional, Rutz, T., additional, Vincenti, G., additional, Coppo, S., additional, Koestner, S., additional, Stuber, M., additional, Schwitter, J., additional, Romana, P., additional, Francesco, S., additional, Gianfranco, B., additional, Mario, C., additional, Massimo, L., additional, Alizadeh Sani, Z., additional, Vojdan-Parast, M., additional, Alimohammadi, M., additional, Sarafan-Sadeghi, S., additional, Seifi, A., additional, Fallahabadi, H., additional, Karami Tanha, F., additional, Jamshidi, M., additional, Hesamy, M., additional, Bonello, B., additional, Sorensen, C., additional, Fouilloux, V., additional, Gorincour, G., additional, Mace, L., additional, Fraisse, A., additional, Jacquier, A., additional, de Meester, C., additional, Amzulescu, M., additional, Bouzin, C., additional, Boileau, L., additional, Melchior, J., additional, Boulif, J., additional, Lazam, S., additional, Pasquet, A., additional, Vancrayenest, D., additional, Vanoverschelde, J., additional, Gerber, B., additional, Loudon, M., additional, Bull, S., additional, Bissell, M., additional, Joseph, J., additional, Neubauer, S., additional, Myerson, S., additional, Dorniak, K., additional, Hellmann, M., additional, Rawicz-Zegrzda, D., additional, W sierska, M., additional, Sabisz, A., additional, Szurowska, E., additional, Heiberg, E., additional, Dudziak, M., additional, Kwok, T., additional, Chin, C., additional, Dweck, M., additional, Hadamitzky, M., additional, Nadjiri, J., additional, Hendrich, E., additional, Pankalla, C., additional, Will, A., additional, Schunkert, H., additional, Martinoff, S., additional, Sonne, C., additional, Pepe, A., additional, Meloni, A., additional, Terrazzino, F., additional, Spasiano, A., additional, Filosa, A., additional, Bitti, P., additional, Tangari, C., additional, Restaino, G., additional, Resta, M., additional, Ricchi, P., additional, Tudisca, C., additional, Grassedonio, E., additional, Positano, V., additional, Piraino, B., additional, Romano, N., additional, Keilberg, P., additional, Midiri, M., additional, Macchi, S., additional, Ambrosio, D., additional, De Marchi, D., additional, Chiodi, E., additional, Salvatori, C., additional, Artang, R., additional, Bogachkov, A., additional, Botelho, M., additional, Bou-Ayache, J., additional, Vazquez, M., additional, Carr, J., additional, Collins, J., additional, Maret, E., additional, Ahlander, B., additional, Bjorklund, P., additional, Engvall, J., additional, Cimermancic, R., additional, Inage, A., additional, Mizuno, N., additional, Santarelli, M., additional, Izzi, G., additional, Maddaloni, D., additional, Landini, L., additional, Carulli, G., additional, Oliva, E., additional, Arcioni, F., additional, Fraticelli, V., additional, Toia, P., additional, Renne, S., additional, Rizzo, M., additional, Reinstadler, S., additional, Klug, G., additional, Feistritzer, H., additional, Aschauer, A., additional, Schocke, M., additional, Franz, W., additional, Metzler, B., additional, Melonil, A., additional, Positanol, V., additional, Roccamo, G., additional, Argento, C., additional, Benni, M., additional, De Marchil, D., additional, Missere, M., additional, Prezios, P., additional, Salvatoril, C., additional, Pepel, A., additional, Rossi, G., additional, Cirotto, C., additional, Filati, G., additional, Preziosi, P., additional, Mongeon, F., additional, Fischer, K., additional, Teixeira, T., additional, Friedrich, M., additional, Marcotte, F., additional, Zenge, M., additional, Schmidt, M., additional, Nadar, M., additional, Chevre, P., additional, Rohner, C., additional, Mouratoglou, S., additional, Kallifatidis, A., additional, Giannakoulas, G., additional, Grapsa, J., additional, Kamperidis, V., additional, Pitsiou, G., additional, Stanopoulos, I., additional, Hadjimiltiades, S., additional, Karvounis, H., additional, Ahmed, N., additional, Lawton, C., additional, Ghosh Dastidar, A., additional, Frontera, A., additional, Jackson, A., additional, Cripps, T., additional, Diab, I., additional, Duncan, E., additional, Thomas, G., additional, Bucciarelli-Ducci, C., additional, Kannoly, S., additional, Gosling, O., additional, Ninan, T., additional, Fulford, J., additional, Dalrymple-Haym, M., additional, Shore, A., additional, Bellenger, N., additional, Alegret, J., additional, Beltran, R., additional, Martin, M., additional, Mendoza, M., additional, Elisabetta, C., additional, Teresa, C., additional, Zairo, F., additional, Marcello, N., additional, Clorinda, M., additional, Bruna, M., additional, Vincenzo, P., additional, Alessia, P., additional, Giorgio, B., additional, Mair, J., additional, Kremser, C., additional, Aschauer, S., additional, Tufaro, C., additional, Kammerlander, A., additional, Pfaffenberger, S., additional, Marzluf, B., additional, Bonderman, D., additional, Mascherbauer, J., additional, Kliegel, A., additional, Sailer, A., additional, Brustbauer, R., additional, Sedivy, R., additional, Mayr, H., additional, Manessi, M., additional, Castelvecchio, S., additional, Votta, E., additional, Stevanella, M., additional, Menicanti, L., additional, Secchi, F., additional, Redaelli, A., additional, Reiter, U., additional, Reiter, G., additional, Kovacs, G., additional, Greiser, A., additional, Olschewski, H., additional, Fuchsjager, M., additional, Babayev, J., additional, Mlynarski, R., additional, Mlynarska, A., additional, Sosnowski, M., additional, Pontone, G., additional, Bertella, E., additional, Petulla, M., additional, Russo, E., additional, Innocenti, E., additional, Baggiano, A., additional, Mushtaq, S., additional, Gripari, P., additional, Andreini, D., additional, Tondo, C., additional, Nyktari, E., additional, Izgi, C., additional, Haidar, S., additional, Wage, R., additional, Keegan, J., additional, Wong, T., additional, Mohiaddin, R., additional, Durante, A., additional, Rimoldi, O., additional, Laforgia, P., additional, Gianni, U., additional, Benedetti, G., additional, Cava, M., additional, Damascelli, A., additional, Laricchia, A., additional, Ancona, M., additional, Aurelio, A., additional, Pizzetti, G., additional, Esposito, A., additional, Margonato, A., additional, Colombo, A., additional, De Cobelli, F., additional, Camici, P., additional, Zvaigzne, L., additional, Sergejenko, S., additional, Kal js, O., additional, Ripley, D., additional, Swarbrick, D., additional, Hossain, E., additional, Chawner, R., additional, Moore, J., additional, Aquaro, G., additional, Barison, A., additional, Masci, P., additional, Todiere, G., additional, Strata, E., additional, Di Bella, G., additional, Monasterio, F., additional, Levelt, E., additional, Mahmod, M., additional, Ntusi, N., additional, Ariga, R., additional, Upton, R., additional, Piechnick, S., additional, Francis, J., additional, Schneider, J., additional, Stoll, V., additional, Davis, A., additional, Karamitsos, T., additional, Leeson, P., additional, Holloway, C., additional, Clarke, K., additional, Karwat, K., additional, Tomala, M., additional, Miszalski-Jamka, K., additional, Mrozi ska, S., additional, Kowalczyk, M., additional, Mazur, W., additional, Kereiakes, D., additional, Nessler, J., additional, Zmudka, K., additional, Ja wiec, P., additional, Miszalski-Jamka, T., additional, Ben Yaacoub-Kzadri, I., additional, Harguem, S., additional, Bennaceur, R., additional, Ganzoui, I., additional, Ben Miled, A., additional, Mnif, N., additional, Rodriguez Palomares, J., additional, Ortiz, J., additional, Tejedor, P., additional, Lee, D., additional, Wu, E., additional, Bonow, R., additional, Khanji, M., additional, Castiello, T., additional, Westwood, M., additional, Petersen, S., additional, Storti, S., additional, Quota, A., additional, Smacchia, M., additional, Paci, C., additional, Vallone, A., additional, Valeri, G., additional, keilberg, P., additional, Gargani, L., additional, Guiducci, S., additional, Pugliese, N., additional, Pingitore, A., additional, Cole, B., additional, Douglas, H., additional, Rodden, S., additional, Horan, P., additional, Harbinson, M., additional, Johnston, N., additional, Dixon, L., additional, Choudhary, P., additional, Hsu, C., additional, Grieve, S., additional, Semsarian, C., additional, Richmond, D., additional, Celermajer, D., additional, Puranik, R., additional, Hinojar Baydes, R., additional, Varma, N., additional, Goodman, B., additional, Khan, S., additional, Arroyo Ucar, E., additional, Dabir, D., additional, Schaeffter, T., additional, Nagel, E., additional, Puntmann, V., additional, Hinojar, R., additional, Ucar, E., additional, Ngah, N., additional, Kuo, N., additional, D'Cruz, D., additional, Gaddum, N., additional, Foote, L., additional, Schnackenburg, B., additional, Higgins, D., additional, Nucifora, G., additional, Muser, D., additional, Morocutti, G., additional, Gianfagna, P., additional, Zanuttini, D., additional, Piccoli, G., additional, Proclemer, A., additional, Prati, G., additional, Vitrella, G., additional, Allocca, G., additional, Buttignoni, S., additional, Delise, P., additional, Sinagra, G., additional, Silva, G., additional, Almeida, A., additional, David, C., additional, Francisco, A., additional, Magalhaes, A., additional, Placido, R., additional, Menezes, M., additional, Guimaraes, T., additional, Mendes, A., additional, Nunes Diogo, A., additional, Aneq, M., additional, Papavassiliu, T., additional, Sandberg, R., additional, Schimpf, R., additional, Schoenberg, S., additional, Borggrefe, M., additional, Doesch, C., additional, Tamin, S., additional, Tan, L., additional, Joshi, S., additional, Memon, S., additional, Tangcharoen, T., additional, Prasertkulchai, W., additional, Yamwong, S., additional, Sritara, P., additional, Binti Ngah, N., additional, Cruz, D., additional, Rebellato, L., additional, Daleffe, E., additional, Facchin, D., additional, Melao, F., additional, Paiva, M., additional, Pinho, T., additional, Martins, E., additional, Vasconcelos, M., additional, Madureira, A., additional, Macedo, F., additional, Ramos, I., additional, Maciel, M., additional, Agoston-Coldea, L., additional, Marjanovic, Z., additional, Hadj Khelifa, S., additional, Kachenoura, N., additional, Lupu, S., additional, Soulat, G., additional, Farge-Bancel, D., additional, Mousseaux, E., additional, Dastidar, A., additional, Augustine, D., additional, McAlindon, E., additional, Leite, S., additional, Sousa, C., additional, Rangel, I., additional, El ghannudi, S., additional, Lefoulon, A., additional, Noel, E., additional, Germain, P., additional, Doutreleau, S., additional, Jeung, M., additional, Gangi, A., additional, Roy, C., additional, Pisciella, L., additional, Zachara, E., additional, Federica, R., additional, Emdin, M., additional, Baydes, R., additional, Mahmoud, I., additional, and Jackson, T., additional

Published
2014
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46. Lung stress and strain during mechanical ventilation : any difference between statics and dynamics?

Author

Protti, A, Andreis, D, Monti, M, Santini, A, Sparacino, C, Langer, T, Votta, E, Gatti, S, Lombardi, L, Leopardi, O, Masson, S, Cressoni, M, Gattinoni, L, Andreis, DT, Sparacino, CC, Protti, A, Andreis, D, Monti, M, Santini, A, Sparacino, C, Langer, T, Votta, E, Gatti, S, Lombardi, L, Leopardi, O, Masson, S, Cressoni, M, Gattinoni, L, Andreis, DT, and Sparacino, CC

Abstract

OBJECTIVE: Tidal volume (VT) and volume of gas caused by positive end-expiratory pressure (VPEEP) generate dynamic and static lung strains, respectively. Our aim was to clarify whether different combinations of dynamic and static strains, resulting in the same large global strain, constantly produce lung edema. DESIGN:: Laboratory investigation. SETTING: Animal unit. SUBJECTS:: Twenty-eight healthy pigs. INTERVENTIONS: After lung computed tomography, 20 animals were ventilated for 54 hrs at a global strain of 2.5, either entirely dynamic (VT 100% and VPEEP 0%), partly dynamic and partly static (VT 75-50%and VPEEP 25-50%), or mainly static (VT 25% and VPEEP 75%) and then killed. In eight other pigs (VT 25% and VPEEP 75%), VPEEP was abruptly zeroed after 36-54 hrs and ventilation continued for 3 hrs. MEASUREMENTS AND MAIN RESULTS: Edema was diagnosed when final lung weight (balance) exceeded the initial weight (computed tomography). Mortality, lung mechanics, gas exchange, pulmonary histology, and inflammation were evaluated. All animals ventilated with entirely dynamic strain (VT 825 ± 424 mL) developed pulmonary edema (lung weight from 334 ± 38 to 658 ± 99 g, p < 0.01), whereas none of those ventilated with mainly static strain (VT 237 ± 21 mL and VPEEP 906 ± 114 mL, corresponding to 19 ± 1 cm H2O of positive end-expiratory pressure) did (from 314 ± 55 to 277 ± 46 g, p = 0.65). Animals ventilated with intermediate combinations finally had normal or largely increased lung weight. Smaller dynamic and larger static strains lowered mortality (p < 0.01), derangement of lung mechanics (p < 0.01), and arterial oxygenation (p < 0.01), histological injury score (p = 0.03), and bronchoalveolar interleukin-6 concentration (p < 0.01). Removal of positive end-expiratory pressure did not result in abrupt increase in lung weight (from 336 ± 36 to 351 ± 77 g, p = 0.51). CONCLUSIONS Lung edema forms (possibly as an all-or-none response) depending not only on global st

Published
2013

48. Poster Session 1: Thursday 8 December 2011, 08:30-12:30 * Location: Poster Area

Author

Vijayan, S., primary, Khanji, M., additional, Ionescu, A., additional, Vijayan, S., additional, Podoleanu, C., additional, Frigy, A., additional, Ugri, A., additional, Varga, A., additional, Podoleanu, D., additional, Incze, A., additional, Carasca, E., additional, Dobreanu, D., additional, Mjolstad, O., additional, Dalen, H., additional, Graven, T., additional, Kleinau, J., additional, Hagen, B., additional, Fu, H., additional, Liu, T., additional, Li, J., additional, Liu, C., additional, Zhou, C., additional, Li, G., additional, Bordese, R., additional, Capriolo, M., additional, Brero, D., additional, Salvetti, I., additional, Cannillo, M., additional, Antolini, M., additional, Grosso Marra, W., additional, Frea, S., additional, Morello, M., additional, Gaita, F., additional, Maffessanti, F., additional, Caiani, E., additional, Muraru, D., additional, Tuveri, F., additional, Dal Bianco, L., additional, Badano, L., additional, Majid, A., additional, Soesanto, A., additional, Ario Suryo Kuncoro, B., additional, Sukmawan, R., additional, Ganesja, M. H., additional, Benedek, T., additional, Chitu, M., additional, Beata, J., additional, Suciu, Z., additional, Kovacs, I., additional, Bucur, O., additional, Benedek, I., additional, Hrynkiewicz-Szymanska, A., additional, Szymanski, F., additional, Karpinski, G., additional, Filipiak, K., additional, Radunovic, Z., additional, Lande Wekre, L., additional, Steine, K., additional, Bech-Hanssen, O., additional, Rundqvist, B., additional, Lindgren, F., additional, Selimovic, N., additional, Jedrzychowska-Baraniak, J., additional, Jozwa, R., additional, Larysz, B., additional, Kasprzak, J., additional, Ripp, T., additional, Mordovin, V., additional, Ripp, E., additional, Ciobanu, A., additional, Dulgheru, R., additional, Dragoi, R., additional, Magda, S., additional, Florescu, M., additional, Mihaila, S., additional, Rimbas, R., additional, Cinteza, M., additional, Vinereanu, D., additional, Benavides-Vallve, C., additional, Pelacho, B., additional, Iglesias, O., additional, Castano, S., additional, Munoz-Barrutia, A., additional, Prosper, F., additional, Ortiz De Solorzano, C., additional, Manouras, A., additional, Sahlen, A., additional, Winter, R., additional, Vardas, P., additional, Brodin, L., additional, Sarvari, S. I., additional, Haugaa, K. H., additional, Zahid, W., additional, Bendz, B., additional, Aaberge, L., additional, Edvardsen, T., additional, Di Bella, G., additional, Pedri, S., additional, Donato, R., additional, Madaffari, A., additional, Zito, C., additional, Stapf, D., additional, Schreckenberg, M., additional, Carerj, S., additional, Yoshikawa, H., additional, Suzuki, M., additional, Kusunose, Y., additional, Hashimoto, G., additional, Otsuka, T., additional, Nakamura, M., additional, Sugi, K., additional, Grapsa, J., additional, Dawson, D., additional, Gin-Sing, W., additional, Howard, L., additional, Gibbs, J., additional, Nihoyannopoulos, P., additional, Smith, B., additional, Coulter, T., additional, Rendon, A., additional, Gorissen, W., additional, Shiran, A., additional, Asmer, I., additional, Adawi, S., additional, Ganaeem, M., additional, Shehadeh, J., additional, Cameli, M., additional, Lisi, M., additional, Righini, F., additional, Maccherini, M., additional, Sani, G., additional, Galderisi, M., additional, Mondillo, S., additional, Kalimanovska-Ostric, D., additional, Nastasovic, T., additional, Jovanovic, I., additional, Milakovic, B., additional, Dostanic, M., additional, Stosic, M., additional, Sasic, I., additional, Sveen, K., additional, Nerdrum, T., additional, Hanssen, K., additional, Dahl-Jorgensen, K., additional, Holte, E., additional, Vegsundvaag, J., additional, Hole, T., additional, Hegbom, K., additional, Wiseth, R., additional, Ikonomidis, I., additional, Lekakis, J., additional, Tritakis, V., additional, Papadakis, I., additional, Kadoglou, N., additional, Tzortzis, S., additional, Trivilou, P., additional, Koukoulis, C., additional, Paraskevaidis, I., additional, Anastasiou-Nana, M., additional, Smedsrud, M. 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J., additional, Vis, J., additional, Van Dijk, A., additional, Van Melle, J., additional, Pieper, P., additional, Vliegen, H., additional, Sieswerda, G., additional, Foukarakis, E., additional, Pitarokilis, A., additional, Kafarakis, P., additional, Kiritsi, A., additional, Klironomos, E., additional, Manousakis, A., additional, Fragiadaki, X., additional, Papadakis, E., additional, and Dermitzakis, A., additional

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2011
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