Search

By influencing fetal brain development pregnancy may be prolonged beyond term for an unknown time period. In late gestation the mother animal (host) is nephrectomized. The urine of the fetus (transplant) is guided to the outside so that the fetal kidneys excrete the host's urinary secretory substances and eventually hypertrophy. The literature on hypertrophy of the (fetal) kidney, placental passage of urinary secretory substances, endocrine function of the (fetal) kidney and extrarenal tissue, prolongation of gestation, and some aspects of the immunological protection of the fetus is critically reviewed. Conclusions as to the eventual realisation of this hypothetic model of organ allotransplantation without rejection are set forth.

Operations, in which a physician removes vital organs of a foetus in order to sustain other organs of the foetus (e. g. the kidneys) in the uterus for an indefinite period and let them work for the gravida, are in accordance with Austrian law if such surgical interventions are carried out within the first three months of pregnancy with the consent of the expectant mother and after previous consultation with a physician; also, if a termination of pregnancy is justified by one of the indications stipulated in Article 97 Paragraph 1 Item 2 of the Austrian Penal Code.

Zwischen 1976 and 1986 haben wir an Ratten, Hunden, Katzen, Kaninchen, Schafen und Affen 204 Operationen an 83 Tieren in 98 Narkosen durchgefuhrt. Von der anfanglichen weiten Laparotomie, weiten Hysterotomie, ausgedehnten Uterusmobilisierung and geringen fetalen Mobilisierung haben wir die Technik verbessert zur minimalen Laparotomie, minimalen Hysterotomie, ausgedehnten Fetusmobilisierung and geringen Uterusmobilisierung. Die Uberlebensraten des Fetus betrugen zuletzt etwa 80%, beim Muttertier 100°/x. Operationen am Fetus: Aorta-, Cava-, Allantoisund Amnionhohlenkatheter, EEG-Elektroden, Hypophysenausschaltung, Pyelo-Amnio-Stomien im Hinblick auf Nephropathie-Korrekturen, Heilung von Muskel, Haut and Knorpel.