12 results on '"Walden, Charlotte M."'
Search Results
2. β-Glucosidase 2 (GBA2) Activity and Imino Sugar Pharmacology
- Author
-
Ridley, Christina M., Thur, Karen E., Shanahan, Jessica, Thillaiappan, Nagendra Babu, Shen, Ann, Uhl, Karly, Walden, Charlotte M., Rahim, Ahad A., Waddington, Simon N., Platt, Frances M., and van der Spoel, Aarnoud C.
- Published
- 2013
- Full Text
- View/download PDF
3. A sequential two meal challenge reveals abnormalities in postprandial TAG but not glucose in men with increasing numbers of metabolic syndrome components
- Author
-
Jackson, Kim G., Walden, Charlotte M., Murray, Peter, Smith, Adrian M., Lovegrove, Julie A., Minihane, Anne M., and Williams, Christine M.
- Published
- 2012
- Full Text
- View/download PDF
4. Accumulation of Glucosylceramide in Murine Testis, Caused by Inhibition of β-Glucosidase 2: IMPLICATIONS FOR SPERMATOGENESIS
- Author
-
Walden, Charlotte M., Sandhoff, Roger, Chuang, Chia-Chen, Yildiz, Yildiz, Butters, Terry D., Dwek, Raymond A., Platt, Frances M., and van der Spoel, Aarnoud C.
- Published
- 2007
- Full Text
- View/download PDF
5. Contributors
- Author
-
Abbas, Sami, primary, AbouLaila, Mahmoud, additional, Acquas, Elio, additional, Adhikary, Biplab, additional, Afzal, M., additional, Agrogiannis, George, additional, Ahmed, Selena, additional, Alao, John P., additional, Almeida, Cristina M.M., additional, Amin, A.R.M. Ruhul, additional, Andrade, J.P., additional, Aruoma, Okezie I., additional, Asaumi, Hiroshi, additional, Assunção, Marco, additional, Augustyniak, Agnieszka, additional, Babcock, George F., additional, Babich, Harvey, additional, Bahorun, Theeshan, additional, Bajerska, Joanna, additional, Baldermann, Susanne, additional, Bandyopadhyay, Sandip Kumar, additional, Banerjee, Shuvojit, additional, Basu, Arpita, additional, Bettuzzi, Saverio, additional, Bhattacharya, Udayan, additional, Bhattacharyya, Anjan, additional, Bhattacharyya, Jharna, additional, Pathy, Nirmala Bhoo, additional, Bigelow, Rebecca L., additional, Bouglé, Dominique, additional, Brighenti, Furio, additional, Bun, Sok-Siya, additional, Byun, Eui-Hong, additional, Calani, Luca, additional, Cardelli, James A., additional, Chalo, R., additional, Chan, Laura, additional, Chan B.sc., Ruth, additional, Chan, Tak Hang, additional, Chang, Hsin-Huei, additional, Chang, Kuang-Hua, additional, Chuen-Chung Chang, Raymond, additional, Charalampos, Proestos, additional, Chatterjee, Indu Bhushan, additional, Chattopadhyay, Subrata, additional, Chen, Chung-Yu, additional, Chen, Di, additional, Chen, Haixia, additional, Hong-Duo, Chen, additional, Chen, Junping, additional, Chen, Po-Chung, additional, Chen, Richie L.C., additional, Chen, Xiaoqiang, additional, Cheng, Tzong-Jih, additional, Chu, Kai On, additional, Chyu, Ming-Chien, additional, Cimpoiu, Claudia, additional, Cuzzocrea, Salvatore, additional, Das, Asankur Sekhar, additional, Das, Dolan, additional, Das, Kaushik, additional, Bruin, Eveline A. de, additional, De Mejia, Elvira, additional, Dejaegher, Bieke, additional, Delaney, Sarah, additional, Dou, Jianpeng, additional, Dou, Q. Ping, additional, Dworakowska, Dorota, additional, Eckhoff, Rachel, additional, Egawa, Tatsuro, additional, Einother, Suzanne, additional, Elango, Ramesh, additional, Elias, Riad, additional, El-Sayed, Nesrine Salah EL-Dine, additional, Feng, Lei, additional, Feng, Wan Yong, additional, Fenu, Sandro, additional, Ferreres, Federico, additional, Figueira, Maria E., additional, Fix, Lindsey N., additional, Frazier, Richard A., additional, Frezza, Michael, additional, Gao, Xing-Hua, additional, García-Viguera, Cristina, additional, Gehrke, Sarah A., additional, Geraldine, Pitchairaj, additional, Ghosh, Arunava, additional, Giesbrecht, Timo, additional, Giunta, Brian, additional, Gil, José Ignacio, additional, Gil-Izquierdo, Angel, additional, Giri, Ashok K., additional, Gleichenhagen, Maike, additional, Grant, Paul S., additional, Gyamfi, Daniel, additional, Hamada, Taku, additional, Haque, Md Abdul, additional, Hara, Yukihiro, additional, Hashimoto, Michio, additional, Hayashi, Nobuyuki, additional, Hayashi, Tstauya, additional, He, Rong-Rong, additional, Heber, David, additional, Henning, Susanne M., additional, Hirata, Yasunobu, additional, Yuen-Shan Ho, Ku, additional, Hosu, Anamaria, additional, Houghton, Jean Marie, additional, Hsiao, Hsien-Yi, additional, Hsieh, Bo-Chuan, additional, Huang, Chun-Hsiung, additional, Huang, Dejian, additional, Hiu-Ling Hung, Clara, additional, Hung, Yueh-Tzu, additional, Hwang, Daniel H., additional, Hyun-Gyun, Yuk, additional, Igarashi, Ikuo, additional, Isobe, Mitsuaki, additional, Jasienska, Grazyna, additional, Jeszka, Jan, additional, Ji, Seon Kim, additional, Jianrong, Li, additional, Jin, Heiying, additional, Jing, Yali, additional, Jinz, Heiying, additional, Jordan, Susan, additional, Jundoria, Arvin, additional, Kalinovsky, Tatiana, additional, Kamunya, S., additional, Kanno, Yoshihiko, additional, Kanrar, Bappaditya, additional, Kao, Yung-Hsi, additional, Kapetanovic, Izet M., additional, Kapiszewska, Maria, additional, Kapsokefalou, Maria, additional, Kavantzas, Nikolaos, additional, Keller, Bradley B., additional, Kerio, Lilian C., additional, Khan, Sara Anees, additional, Kim, Jong-Min, additional, Kojima-Yuasa, Akiko, additional, Kokotkiewicz, Adam, additional, Komaitis, Michael, additional, Kottur, Govindasamy, additional, Koutelidakis, Antonios E., additional, Ku, Hui-Chen, additional, Kua, Ee-Heok, additional, Kuhnert, Nikolai, additional, Kuo, Yow-Chii, additional, Kurihara, Hiroshi, additional, Kuriyama, Shinichi, additional, Lanzett, Manuella, additional, Le, Anh D., additional, Lee, Andy H., additional, Lee, Joo Young, additional, Lee, Maw-Rong, additional, Lee, Ren-Jye, additional, Lee, Seung-Cheol, additional, Lee, Viola S.Y., additional, Li, Na-Na, additional, Li, Wei, additional, Li, Yuan-Hong, additional, Liang, Yue-Rong, additional, Lin, Chih-Ming, additional, Lin, Ching-Ling, additional, Liu, Chi-Wei, additional, Liu, Hang-Seng, additional, Liu, Pengxin, additional, Longoni, Rosanna, additional, Lorenz, Mario, additional, Lu, Jian-Liang, additional, Lu, Ya-Ning, additional, Lucas, Edralin A., additional, Łuczaj, Wojciech, additional, Luczkiewicz, Maria, additional, Luximon-Ramma, Amitabye, additional, Lynch, Paul, additional, Lyons, Timothy J., additional, Ma, Xiao, additional, Maeda-Yamamoto, Mari, additional, Mahungu, Symon M., additional, Makabe, Hidefumi, additional, Mao, Jenny T., additional, Mariga, Irvine K., additional, Maritim, T., additional, Martin, Colin R., additional, Masuda, Shuichi, additional, Matsui-Yuasa, Isao, additional, Mbuthia, Stephen Karori, additional, Medina, Sonia, additional, Mehra, Aradhana, additional, Melzig, Matthias F., additional, Merklinger-Gruchala, Anna, additional, Meydani, Mohsen, additional, Miclaus, Vasile, additional, Mitra, Chandan, additional, Miyamoto, Yohei, additional, Momoi, Nobuo, additional, Mousa, S.A., additional, Mudau, Fhatuwani Nixwell, additional, Mujtaba, Taskeen, additional, Mumy, Karen L., additional, Murakami, Akira, additional, Murase, Takatoshi, additional, Murugan, Ramalingam Senthil, additional, Murugesan, Subramanian, additional, Nagai, Ryozo, additional, Nagini, Siddavaram, additional, Nagle, Christina, additional, Nakajima, Kei, additional, Neergheen-Bhujun, Vidushi, additional, Ng, Tze-Pin, additional, Ngure, Francis Muigai, additional, Niedzwiecki, Aleksandra, additional, Niu, Kaijun, additional, Nomani, M., additional, O'Brien, Peter, additional, Ogawa, Masahito, additional, Oh, Eung Seok, additional, Okamoto, Kazushi, additional, Ollivier, Evelyne, additional, Osterburg, Andrew R., additional, Otsuki, Makoto, additional, Pang, Chi Pui, additional, Pasalich, Maria, additional, Paterniti, Irene, additional, Patsouris, Efstratios, additional, Persson, Ingrid A.-L., additional, Piljac, Ante, additional, Piljac-Zegarac, Jasenka, additional, Porto, Luís Cristóvão, additional, Prendergast, Mark A., additional, Pripdeevech, Patcharee, additional, Priyamvada, Shubha, additional, Puangpraphant, Sirima, additional, Senthil Kumar, Ramasamy Shanmugasundaram, additional, M., Gregory Raner, additional, Rath, Matthias, additional, Del Rio, Daniele, additional, Rizk, Sherine M., additional, Rizzi, Federica, additional, Robinson, Randy J., additional, Rodrigues, Jorge, additional, Roomi, M. Waheed, additional, Ross, Colleen Margaret, additional, Safer, Abdel-Majeed A., additional, Saikat, Sohel, additional, Sama, Andrew E., additional, Šamec, Dunja, additional, Sameshima, Yoichi, additional, Schuck, Alyssa G., additional, Seong, Baik-Lin, additional, Sharma, Anubha, additional, Shen, Chwan-Li, additional, Sheu, Joen-Rong, additional, Shih, Li-Jane, additional, Shimamura, Yuko, additional, Shin, Dong Moon, additional, Shitandi, Anakalo A., additional, Skrzydlewska, Elżbieta, additional, Smith, Thomas J., additional, Somanah, Jhoti, additional, Song, Jae-Min, additional, Spina, Liliana, additional, Stepp, John Richard, additional, Stoicov, Calin, additional, Sun, Guang-Huan, additional, Suzuki, Jun-ichi, additional, Tachibana, Hirofumi, additional, Tan, Jun, additional, Tang, Nelson L.S., additional, Tang, Xudong, additional, Theodore, Joseph, additional, Thomas, Philip A., additional, Tobita, Kimimasa, additional, Toolsee, Naushad A., additional, Tzen, Jason T.C., additional, Uiterwaal, Cuno S.P.M., additional, Valenca, Samuel Santos, additional, van Buren, Leo, additional, Butler, Tracy R., additional, van der Pijl, Pieter C., additional, Heyden, Yvan Vander, additional, Vignes, Michel, additional, Vinci, Stefania, additional, Wachira, Francis, additional, Walden, Charlotte M., additional, Wan, Luke, additional, Wang, Chi Chiu, additional, Wang, Haichao, additional, Wang, Piwen, additional, Wanyoko, J.K., additional, Watanabe, Naoharu, additional, Weisburg, Jeffrey H., additional, Weiss, David J., additional, Weng, Jueng-Tsueng, additional, Wink, Michael, additional, Chian Wong, Adeline Ik, additional, Wongpornchai, Sugunya, additional, Woo, Jean, additional, Wozniewicz, Malgorzata, additional, Wu, Bo-Tsung, additional, Wu, Yan, additional, Xiaoqiang, Chen, additional, Yadav, Sudhir Kumar, additional, Yamada, Hiroshi, additional, Yang, Ya Ping, additional, Yang, Ziyin, additional, Chien-Chih, Yeh, additional, Yu, Hyun-Gyun, additional, Yusufi, Ahad N.K., additional, Zahreldin, Ahmad A., additional, Zhang, Hongzheng, additional, Zhang, Liang, additional, Zhang, Baohong, additional, Zhang, Bei, additional, Zhang, Chunxia, additional, Zhang, Jing-Song, additional, Zhang, Lan, additional, Zhang, Li, additional, Zhang, Qunzhou, additional, Zhang, Zheng-Zhu, additional, Zhao, Ling, additional, Zhou, Keyuan, additional, Zhou, Limin, additional, Zhu, Dalong, additional, Zhu, Shu, additional, Zimmermann, Benno F., additional, Zingg, Jean-Marc, additional, Zuckerbraun, Harriet L., additional, and Zuo, Zhong, additional
- Published
- 2013
- Full Text
- View/download PDF
6. Attention Benefits of Tea and Tea Ingredients
- Author
-
Einöther, Suzanne J.L., primary, Giesbrecht, Timo, additional, Walden, Charlotte M., additional, van Buren, Leo, additional, van der Pijl, Pieter C., additional, and de Bruin, Eveline A., additional
- Published
- 2013
- Full Text
- View/download PDF
7. Long-term non-hormonal male contraception in mice using N-butyldeoxynojirimycin
- Author
-
Walden, Charlotte M., Butters, Terry D., Dwek, Raymond A., Platt, Frances M., and van der Spoel, Aarnoud C.
- Published
- 2006
8. The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study
- Author
-
Boomkamp Stephanie, Gottwald Ulrich, Leifke Eckhard, Fritsch Martin, Voigtmann Ulrike, Walden Charlotte M, Bone Wilhelm, Platt Frances M, and van der Spoel Aarnoud C
- Subjects
Gynecology and obstetrics ,RG1-991 ,Reproduction ,QH471-489 - Abstract
Abstract Background A major event in the post-meiotic development of male germ cells is the formation of the acrosome. This process can be perturbed in C57BL/6 mice by administration of the small molecule miglustat (N-butyldeoxynojirimycin, NB-DNJ). The miglustat-treated mice produce morphologically abnormal spermatozoa that lack acrosomes and are poorly motile. In C57BL/6 mice, miglustat can be used to maintain long-term reversible infertility. In contrast, when miglustat was evaluated in normal men, it did not affect spermatogenesis. To gain more insight into this species difference we have now evaluated the reproductive effects of miglustat in rabbits, in multiple mouse strains and in interstrain hybrid mice. Methods Male mice of 18 inbred strains were administered miglustat orally or via miniosmotic pumps. Rabbits were given the compound in their food. Fourth-generation interstrain hybrid mice, bred from C57BL/6 and FVB/N mice (which differ in their response to miglustat), also received the drug. Data on fertility (natural mating), sperm motility and morphology, acrosome status, and serum drug levels were collected. Results In rabbits the drug did not induce aberrations of sperm shape or motility, although the serum level of miglustat in rabbits far exceeded the level in C57BL/6 mice (8.4 μM and 0.5 μM, respectively). In some strains of the Swiss and Castle lineages of inbred mice miglustat did not cause infertility, severe morphological sperm aberrations or reduced sperm motility. In these strains miglustat only had milder effects. However, miglustat strongly disturbed acrosome and sperm nucleus development in AKR/J and BALB/c mice and in a number of C57BL/6-related strains. The consequences of drug administration in the interstrain hybrid mice were highly variable. Judging by the number of grossly abnormal spermatozoa, these genetically heterogeneous mice displayed a continuous range of intermediate responses, distinct from either of their parental strains. Conclusion The effects of miglustat on spermatogenesis in mice are strain-dependent, while in rabbits the drug is ineffective. Evaluation of interstrain hybrid mice indicated that the sensitivity of spermatogenesis to miglustat is a quantitative trait. These studies pave the way for identifying the genetic factors underlying the strain/species differences in the effect of miglustat.
- Published
- 2007
- Full Text
- View/download PDF
9. Greater impairment of postprandial triacylglycerol than glucose response in metabolic syndrome subjects with fasting hyperglycaemia
- Author
-
Jackson, Kim G., Walden, Charlotte M., Murray, Peter, Smith, Adrian M., Minihane, Anne M., Lovegrove, Julie A., and Williams, Christine M.
- Published
- 2013
- Full Text
- View/download PDF
10. Chapter 115 - Attention Benefits of Tea and Tea Ingredients: A Review of the Research to Date
- Author
-
Einöther, Suzanne J.L., Giesbrecht, Timo, Walden, Charlotte M., van Buren, Leo, van der Pijl, Pieter C., and de Bruin, Eveline A.
- Published
- 2013
- Full Text
- View/download PDF
11. The sensitivity of murine spermiogenesis to miglustat is a quantitative trait: a pharmacogenetic study
- Author
-
Bone, Wilhelm, primary, Walden, Charlotte M, additional, Fritsch, Martin, additional, Voigtmann, Ulrike, additional, Leifke, Eckhard, additional, Gottwald, Ulrich, additional, Boomkamp, Stephanie, additional, Platt, Frances M, additional, and van der Spoel, Aarnoud C, additional
- Published
- 2007
- Full Text
- View/download PDF
12. Alkylated Imino Sugars, Reversible Male Infertility-Inducing Agents, Do Not Affect the Genetic Integrity of Male Mouse Germ Cells During Short-Term Treatment Despite Induction of Sperm Deformities1
- Author
-
Suganuma, Ryota, primary, Walden, Charlotte M., additional, Butters, Terry D., additional, Platt, Frances M., additional, Dwek, Raymond A., additional, Yanagimachi, Ryuzo, additional, and van der Spoel, Aarnoud C., additional
- Published
- 2005
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.