202 results on '"Walker, John K."'
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2. Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney
3. Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function
4. Development and pharmacological evaluation of a new chemical series of potent pan-ERR agonists, identification of SLU-PP-915
5. Development of a Fragment-Based Machine Learning Algorithm for Designing Hybrid Drugs Optimized for Permeating Gram-Negative Bacteria
6. AdeIJK Pump-Specific Inhibitors Effective against Multidrug Resistant Acinetobacter baumannii
7. Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB
8. Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs
9. Novel Pan-ERR Agonists Ameliorate Heart Failure Through Enhancing Cardiac Fatty Acid Metabolism and Mitochondrial Function
10. Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain
11. International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily—Update 2023
12. An Unusual Base-Sensitive Beta-Elimination Reaction to Synthesize Cinnamamides Starting From Common intermediate of Preparing Phthalides
13. Identification and structure-activity relationships for a series of N, N-disubstituted 2-aminobenzothiazoles as potent inhibitors of S. aureus
14. The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB
15. A Synthetic ERRα Agonist Induces an Acute Aerobic Exercise Response and Enhances Exercise Capacity
16. Analysis of Orthogonal Efflux and Permeation Properties of Compounds Leads to the Discovery of New Efflux Pump Inhibitors
17. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
18. Novel ERR pan-agonists ameliorate heart failure through boosting cardiac fatty acid metabolism and mitochondrial function
19. Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides
20. A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2
21. Bacterial Efflux Pumps and Their Inhibitors
22. Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa
23. Multidrug Efflux Pumps and the Two-Faced Janus of Substrates and Inhibitors
24. GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain
25. A Selective ERRα/γ Inverse Agonist, SLU-PP-1072, Inhibits the Warburg Effect and Induces Apoptosis in Prostate Cancer Cells
26. Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold
27. Machine Learning Algorithm Identifies an Antibiotic Vocabulary for Permeating Gram-Negative Bacteria
28. Acute Lymphoid and Gastrointestinal Toxicity Induced by Selective p38α Map Kinase and Map Kinase-Activated Protein Kinase-2 (MK2) Inhibitors in the Dog
29. Literature and Religion in Germany 1770-1830
30. Estrogen-related receptor agonism reverses mitochondrial dysfunction and inflammation in the aging kidney
31. Small Molecule Condensin Inhibitors
32. Molecular Properties That Define the Activities of Antibiotics in Escherichia coli and Pseudomonas aeruginosa
33. New fluorobutenolide templates for synthesis
34. MORS Designates the Barchi Award Honoring Best Working Group Papers
35. MORS WORKING GROUP INITIATIVE
36. TANDING MANAGEMENT COMMITTEE
37. MORS PRESIDENT'S NOTE
38. Structural bioinformatics-based prediction of exceptional selectivity of p38 MAP kinase inhibitor PH-797804
39. Identification and Structure–Activity Relationships of Novel Compounds that Potentiate the Activities of Antibiotics in Escherichia coli
40. The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein
41. Identification of C3b-Binding Small-Molecule Complement Inhibitors Using Cheminformatics
42. Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump
43. Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain.
44. Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism
45. PRESIDENTS NOTE
46. Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase
47. Design, synthesis and activity of a potent, selective series of N-aryl pyridinone inhibitors of p38 kinase
48. Investigation of the pyrazinones as PDE5 inhibitors: Evaluation of regioisomeric projections into the solvent region
49. 1-(2-(2,2,2-Trifluoroethoxy)ethyl-1 H-pyrazolo[4,3- d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors
50. 1-(2-Ethoxyethyl)-1 H-pyrazolo[4,3- d]pyrimidines as potent phosphodiesterase 5 (PDE5) inhibitors
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