643 results on '"Wambaugh, John"'
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2. Characterizing surface water concentrations of hundreds of organic chemicals in United States for environmental risk prioritization
3. In vitro to in vivo extrapolation and high-content imaging for simultaneous characterization of chemically induced liver steatosis and markers of hepatotoxicity
4. Reproducibility of organ-level effects in repeat dose animal studies
5. Characterizing Chemical Exposure Trends from NHANES Urinary Biomonitoring Data
6. Cutting-edge computational chemical exposure research at the U.S. Environmental Protection Agency
7. Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment
8. Bayesian inference of chemical exposures from NHANES urine biomonitoring data
9. Exposure forecasting – ExpoCast – for data-poor chemicals in commerce and the environment
10. Simulating toxicokinetic variability to identify susceptible and highly exposed populations
11. The chemical landscape of high-throughput new approach methodologies for exposure
12. Consensus Modeling of Median Chemical Intake for the U.S. Population Based on Predictions of Exposure Pathways
13. Evaluation of a rapid, generic human gestational dose model
14. In Vitro Hepatic Clearance Evaluations of Per- and Polyfluoroalkyl Substances (PFAS) across Multiple Structural Categories.
15. Predicting compound amenability with liquid chromatography-mass spectrometry to improve non-targeted analysis
16. Opportunities and challenges related to saturation of toxicokinetic processes: Implications for risk assessment
17. Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies
18. Repeat-dose toxicity prediction with Generalized Read-Across (GenRA) using targeted transcriptomic data: A proof-of-concept case study
19. GRADE Guidelines 30: the GRADE approach to assessing the certainty of modeled evidence—An overview in the context of health decision-making
20. Using chemical structure information to develop predictive models for in vitro toxicokinetic parameters to inform high-throughput risk-assessment
21. Pharmacokinetic profile of Perfluorobutane Sulfonate and activation of hepatic nuclear receptor target genes in mice
22. PBPK model reporting template for chemical risk assessment applications
23. High-throughput toxicogenomic screening of chemicals in the environment using metabolically competent hepatic cell cultures
24. Development and evaluation of a high throughput inhalation model for organic chemicals
25. New approach methodologies for exposure science
26. Estimating uncertainty in the context of new approach methodologies for potential use in chemical safety evaluation
27. A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS).
28. Force networks and elasticity in granular silos
29. Response to perturbations for granular flow in a hopper
30. Simple models for granular force networks
31. In vitro to in vivo extrapolation for high throughput prioritization and decision making
32. Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments
33. Database of pharmacokinetic time-series data and parameters for 144 environmental chemicals
34. Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments
35. Screening for drinking water contaminants of concern using an automated exposure-focused workflow
36. Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) Using Gas Chromatography Coupled with Mass Spectrometry
37. Plasma Protein Binding Evaluations of Per- and Polyfluoroalkyl Substances for Category-Based Toxicokinetic Assessment
38. Suspect Screening Analysis of Pooled Human Serum Samples Using GC × GC/TOF-MS.
39. Dosimetric Anchoring of Toxicological Studies
40. Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA
41. A Data-Driven Approach to Estimating Occupational Inhalation Exposure Using Workplace Compliance Data
42. Characterization and prediction of chemical functions and weight fractions in consumer products
43. Integrating tools for non-targeted analysis research and chemical safety evaluations at the US EPA
44. A Machine Learning Model to Estimate Toxicokinetic Half-Lives of Per- and Polyfluoro-Alkyl Substances (PFAS) in Multiple Species
45. Identifying xenobiotic metabolites with in silico prediction tools and LCMS suspect screening analysis
46. A regression analysis using simple descriptors for multiple dermal datasets: Going from individual membranes to the full skin
47. A geospatial modeling approach to quantifying the risk of exposure to environmental chemical mixtures via a common molecular target
48. Exploring consumer exposure pathways and patterns of use for chemicals in the environment
49. Characterizing surface water concentrations of hundreds of organic chemicals in United States for environmental risk prioritization
50. Characterizing pathways of exposure for risk-based chemical prioritization
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