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Objective: To investigate drug knowledge of middle school students in HIV prone areas in Liangshan of Sichuan Province., Methods: Students were randomly selected from the middle schools located in the HIV prone areas in Liangshan. A questionnaire survey was conducted. Drug knowledge of the respondents and associated factors were analyzed., Results: Of the 10 749 respondents,10.1% had wrong knowledge about drugs. The respondents of male gender and minority ethnicity in the region and those who were in a lower grade,had poor academic records,more sisters,and a schoolmate taking drugs,and lived in a family with HIV infected member were more likely to had poor drug knowledge. By contrast,the respondents who had a peasant father,lived with both parents,resided in a city or township,self-rated in the middle and low 1/3 of wealth,lived in a community with >50% school attendance,and had a family member taking drugs were less likely to have wrong drug knowledge., Conclusion: Middle school students in the HIV prone areas in Liangshan have poor drug knowledge. Socioeconomic factors influence the drug knowledge of students,which require systematic interventions., (Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).)

A facile aqueous chemical approach is developed for one-pot synthesis of the nanocomposites of heavily doped semiconductor nanoparticles (Cu 2-x Se NPs) and reduced graphene oxide (rGO) at room temperature, wherein the reduction of GO and the in situ growth of Cu 2-x Se NPs on rGO sheets occur simultaneously. The as-prepared Cu 2-x Se/rGO nanocomposites exhibit a well-defined near-infrared (NIR) localized surface plasmon resonance (LSPR), which arises from free carriers (holes) and could be tuned from 1360 to 1050 nm by varying the reaction time, owing to the increase of the free carrier density in the valence band of Cu 2-x Se NPs. This approach not only offers an efficient strategy to synthesize the self-doped Cu 2-x Se/rGO nanocomposites with strong and tunable NIR absorption, but also develops new light scattering nanoprobes with good biocompatibility as well as unique optical properties for in vitro cellular dark-field microscopic imaging (iDFM).