24 results on '"Wan‐Yin, Shi"'
Search Results
2. Investigation of the molecular mechanism underlying the inhibitory activities of ethanol extract of Bombyx mori pupa-incubated Cordyceps militaris fruiting bodies toward allergic rhinitis
- Author
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Ting-Feng Wu, Wan-Yin Shi, Yi-Chen Chiu, and Yu-Yi Chan
- Subjects
Cordyceps militaris ,Allergic rhinitis ,CM-EE ,Ca2+ ion mobilization ,PKC ,Syk ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Cordyceps militaris has been widely studied for its various pharmacological activities such as antitumor, anti-inflammation, and immune regulation. The binding of an allergen to IgE-sensitized mast cells in nasal mucosa triggers allergic rhinitis. We found that oral administration of 300 mg/kg of the ethanol extract prepared from silkworm pupa-cultivated Cordyceps militaris fruiting bodies significantly alleviated the symptoms of ovalbumin-induced allergic rhinitis in mice, including sneeze/scratch, mast cell activation, eosinophil infiltration, and Syk activation. The treatment of ethanol extract significantly suppressed the release of β-hexosaminidase (a degranulation marker) and mRNA expression levels of various cytokines, including IL-3, IL-10, and IL-13 in activated RBL2H3 cells. The ethanol extract and β-sitostenone, which was purified from the extract, could respectively reduce the Ca2+ ion mobilization in activated RBL-2H3 cells. Furthermore, results collected from western immunoblotting demonstrated that ethanol extract significantly retarded Ca2+ ion mobilization-initiated signaling cascade, which provoked the expression of various allergic cytokines. Also, the extract incubation interfered with P38 as well as NF-kB activation and Nrf-2 translocation. Our study suggested that ethanol extract possessed some natural constituents which could inhibit immediate degranulation and de novo synthesis of allergic cytokines via inhibition of Ca2+ ion mobilization in mast cells in the nasal mucosa of allergic rhinitis mice.
- Published
- 2021
- Full Text
- View/download PDF
3. Preresection Stained Glue Injection to Localize Pulmonary Small Nodules and Ground-glass Opacities
- Author
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Jian Wang, Li-Bin Gao, Hong Zhang, Liang Liu, and Wan-Yin Shi
- Subjects
Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung Neoplasms ,030204 cardiovascular system & hematology ,Palpation ,localization ,030218 nuclear medicine & medical imaging ,law.invention ,Resection ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,law ,Preoperative Care ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Pulmonary hematoma ,Cyanoacrylates ,GLUE ,Retrospective Studies ,Blue dye ,medicine.diagnostic_test ,Thoracic Surgery, Video-Assisted ,business.industry ,Solitary Pulmonary Nodule ,pulmonary nodule ,computed tomography ,Original Articles ,Middle Aged ,ground-glass opacity ,medicine.disease ,video-assisted thoracoscopic surgery ,Methylene Blue ,Pneumothorax ,Cyanoacrylate ,Multiple Pulmonary Nodules ,Female ,Radiology ,medicine.symptom ,business - Abstract
Objective We sought to introduce a localization procedure (methylene blue-stained N-butyl cyanoacrylate and N-octyl cyanoacrylate glue) in localizing pulmonary small nodules and ground-glass opacities before thoracoscopic resection, and to evaluate its efficacy. Methods A total of 20 patients with pulmonary small nodules and/or ground-glass opacities, who underwent video-assisted thoracoscopic surgery from August 1, 2017 to March 1 2018, were included in the study. Results A total of 24 lesions in 20 patients underwent blue-stained glue localization. The success rate of localization was 100%, with a mean dose of 0.04±0.01 mL blue dye and 1 mL glue used for each lesion. The average time for the whole localization procedure was 15.4±6.3 minutes. All lesions were intraoperatively localized by visual inspection in combination with palpation. The complications related to the localization procedure included mild pneumothorax occurring in 9 patients and minor pulmonary hematoma in 4 patients. No pain or distress was reported. Conclusions Blue-stained glue injection is technically feasible and safe to localize pulmonary small nodules and ground-glass opacities before thoracoscopic resection.
- Published
- 2020
4. Non-enhanced multimodal magnetic resonance imaging in assessment of iliac vein obstruction with or without thrombosis
- Author
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Jianping Gu, Hai-Lin Xue, Liang Chen, and Wan-Yin Shi
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medicine.medical_specialty ,Magnetic Resonance Spectroscopy ,Urology ,Iliac Vein ,Fluid-attenuated inversion recovery ,Sensitivity and Specificity ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Thrombus ,Vein ,Isovolumetric contraction ,Venous Thrombosis ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Gastroenterology ,Magnetic resonance imaging ,Digital subtraction angiography ,medicine.disease ,Magnetic Resonance Imaging ,Thrombosis ,Venous thrombosis ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Radiology ,business ,Magnetic Resonance Angiography - Abstract
To evaluate the diagnostic accuracy of a contrast-free multimodal magnetic resonance (MR) protocol (including M2DIPEAR, THRIVE, BTFE-SPAIR, and FLAIR sequences) in the detection of iliac vein obstruction with or without thrombosis. From May 1st, 2015, to May 1st, 2016, a total of 73 patients (aged 51.33 ± 4.21 years) who received both digital subtraction angiography (DSA) and the multimodal MR imaging were included. The protocol of the multimodal MR included M2DIPEAR and BTFE-SPAIR for presenting iliac vein obstruction, and THRIVE and FLAIR for revealing the co-existed thrombosis. Three observers who were blinded to clinical and DSA results independently analyzed all multimodal MR datasets. Per-patient evaluations on presence or absence of iliac vein obstruction were performed to calculate the diagnostic performance of MR imaging (DSA regarded as gold reference) in terms of overall accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). Capability to display the co-existing venous thrombus was also evaluated per-MR sequence using a 3-point scale system. Iliac vein obstruction was depicted with DSA in 64 patients. In per-patient evaluation, the multimodal MR imaging yielded accuracy of 95.9% (70/73), sensitivity of 96.9% (62/64), specificity of 88.9% (8/9), positive predictive value of 98.4% (62/63), and negative predictive value of 80% (8/10), respectively. In the multimodal MR sequences, balanced turbo field echo—spectral attenuated inversion recovery (BTFE-SPAIR) sequence was superior to other sequences in depicting the iliac vein configuration, but fluid attenuated inversion recovery (FLAIR) and T1 high-resolution isovolumetric examination (THRIVE) seemed superior in detecting co-existing venous thrombosis. M2DIPEAR and BTFE-SPAIR sequence can reveal iliac vein obstruction while THRIVE and FLAIR can detect the co-existed thrombosis. The proposed multimodal MR protocol can accurately depict the iliac vein obstruction and accurately detect the co-existing venous thrombosis comparable with that of DSA.
- Published
- 2021
5. Azygous Anterior Cerebral Artery and Associated Aneurysms: Detection and Identification Using 3-Dimensional Time-of-Flight Magnetic Resonance Angiography
- Author
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Wan-Yin, Shi, Ming-Hua, Li, Bin-Xian, Gu, Yong-Dong, Li, and Hua-Qiao, Tan
- Published
- 2014
- Full Text
- View/download PDF
6. Investigation of the molecular mechanism underlying the inhibitory activities of ethanol extract of Bombyx mori pupa-incubated Cordyceps militaris fruiting bodies toward allergic rhinitis
- Author
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Yi-Chen Chiu, Wan-Yin Shi, Yu-Yi Chan, and Ting-Feng Wu
- Subjects
0301 basic medicine ,Male ,Syk ,Mucous membrane of nose ,Pharmacology ,medicine.disease_cause ,Allergic rhinitis ,Cell Degranulation ,chemistry.chemical_compound ,0302 clinical medicine ,Allergen ,Anti-Allergic Agents ,Mast Cells ,PKC ,Mice, Inbred BALB C ,biology ,Chemistry ,Degranulation ,General Medicine ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Larva ,CM-EE ,Cytokines ,Ovalbumin ,p38 mitogen-activated protein kinases ,RM1-950 ,03 medical and health sciences ,Cell Line, Tumor ,Cordyceps militaris ,medicine ,Ca2+ ion mobilization ,Animals ,Calcium Signaling ,Fruiting Bodies, Fungal ,Ethanol ,Eosinophil ,biology.organism_classification ,Bombyx ,Rhinitis, Allergic ,Rats ,Disease Models, Animal ,Nasal Mucosa ,030104 developmental biology ,Cordyceps ,Solvents ,Therapeutics. Pharmacology - Abstract
Cordyceps militaris has been widely studied for its various pharmacological activities such as antitumor, anti-inflammation, and immune regulation. The binding of an allergen to IgE-sensitized mast cells in nasal mucosa triggers allergic rhinitis. We found that oral administration of 300 mg/kg of the ethanol extract prepared from silkworm pupa-cultivated Cordyceps militaris fruiting bodies significantly alleviated the symptoms of ovalbumin-induced allergic rhinitis in mice, including sneeze/scratch, mast cell activation, eosinophil infiltration, and Syk activation. The treatment of ethanol extract significantly suppressed the release of β-hexosaminidase (a degranulation marker) and mRNA expression levels of various cytokines, including IL-3, IL-10, and IL-13 in activated RBL2H3 cells. The ethanol extract and β-sitostenone, which was purified from the extract, could respectively reduce the Ca2+ ion mobilization in activated RBL-2H3 cells. Furthermore, results collected from western immunoblotting demonstrated that ethanol extract significantly retarded Ca2+ ion mobilization-initiated signaling cascade, which provoked the expression of various allergic cytokines. Also, the extract incubation interfered with P38 as well as NF-kB activation and Nrf-2 translocation. Our study suggested that ethanol extract possessed some natural constituents which could inhibit immediate degranulation and de novo synthesis of allergic cytokines via inhibition of Ca2+ ion mobilization in mast cells in the nasal mucosa of allergic rhinitis mice.
- Published
- 2020
7. Endovascular treatment for iliac vein compression syndrome with or without lower extremity deep vein thrombosis: A retrospective study on mid-term in-stent patency from a single center
- Author
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Jianping Gu, Wensheng Lou, Xu He, Wan-Yin Shi, and Chang-Jian Liu
- Subjects
Male ,medicine.medical_specialty ,Percutaneous ,Deep vein ,medicine.medical_treatment ,Iliac Vein ,030204 cardiovascular system & hematology ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Angioplasty ,May-Thurner Syndrome ,Humans ,Medicine ,Vascular Patency ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Vein ,Aged ,Retrospective Studies ,Venous Thrombosis ,business.industry ,Anticoagulants ,General Medicine ,Middle Aged ,medicine.disease ,May–Thurner syndrome ,Thrombosis ,Surgery ,Venous thrombosis ,Treatment Outcome ,medicine.anatomical_structure ,Lower Extremity ,cardiovascular system ,Female ,Stents ,Radiology ,business ,Follow-Up Studies - Abstract
Purpose The purpose of this study was to evaluate mid-term patency of iliac vein following endovascular treatment for iliac vein compression syndrome (IVCS) with or without deep venous thrombosis (DVT). Materials and methods The authors’ institutional review board approved the study. Two hundred and thirty-three consecutive patients with IVCS were treated with endovascular treatment and followed up. The therapeutic strategies and complications were recorded. Cumulative patency was assessed with Kaplan–Meier curves. Independent predictors of in-stent obstruction were calculated with the Cox regression model. Results Endovascular treatment was technically successful in 225 of the 233 patients (96.6%). All of 225 patients were treated with percutaneous transluminal angioplasty and stent placement. No severe procedure-related complications occurred. The cumulative 1-, 3- and 5-year primary patency rates over a median follow-up time of 34 months (range, 0.3–82 months) were 93.2%, 84.3% and 74.5%, respectively. Independent predictors for in-stent obstruction included use of multiple stents and irregular stocking wearing. The cumulative 1-, 3-, 5-year secondary patency rates were 100%, 93.3% and 92%, respectively. Conclusions Endovascular treatment could achieve favorable mid-term patency in patients with IVCS with or without DVT.
- Published
- 2016
8. Uncovering the Molecular Mechanism of Anti-Allergic Activity of Silkworm Pupa-Grown Cordyceps militaris Fruit Body
- Author
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Wan-Yin Shi, Yu-Yi Chan, Meng-Ting Jhong, and Ting-Feng Wu
- Subjects
0301 basic medicine ,Cell Degranulation ,Pharmacology ,Immunoglobulin E ,Cell Line ,03 medical and health sciences ,0302 clinical medicine ,Cordyceps militaris ,Anti-Allergic Agents ,Animals ,Mast Cells ,Interleukin 4 ,Cordyceps ,biology ,Tumor Necrosis Factor-alpha ,Degranulation ,General Medicine ,biology.organism_classification ,Bombyx ,beta-N-Acetylhexosaminidases ,Rats ,030104 developmental biology ,Complementary and alternative medicine ,Biochemistry ,Cell culture ,030220 oncology & carcinogenesis ,Larva ,biology.protein ,Cytokines ,Tumor necrosis factor alpha ,Calcium ,Interleukin-4 - Abstract
Cordyceps militaris has been widely used as an herbal drug and tonic food in East Asia and has also been recently studied in the West because of its various pharmacological activities such as antitumoral, anti-inflammatory and immunomodulatory effects. In this study, we examined the molecular mechanism underlying the anti-allergic activity of ethanol extract prepared from silkworm pupa-cultivated Cordyceps militaris fruit bodies in activated mast cells. Our results showed that ethanol extract treatment significantly inhibited the release of [Formula: see text]-hexosaminidase (a degranulation marker) and mRNA levels of tumor necrosis factor-[Formula: see text] as well as interleukin-4 in RBL-2H3 cells. The cells were sensitized with 2,4-dinitrophenol specific IgE and then stimulated with human serum albumin conjugated with 2,4-dinitrophenol. Oral administration of 300[Formula: see text]mg/kg ethanol extract significantly ameliorated IgE-induced allergic reaction in mice with passive cutaneous anaphylaxis. Western immunoblotting results demonstrated that ethanol extract incubation significantly inhibited Syk/PI3K/MEKK4/JNK/c-jun biochemical cascade in activated RBL-2H3 cells, which activated the expression of various allergic cytokines. In addition, it suppressed Erk activation and PLC[Formula: see text] evocation, which would respectively evoke the synthesis of lipid mediators and Ca[Formula: see text] mobilization to induce degranulation in stimulated RBL-2H3 cells. A compound, identified as [Formula: see text]-sitostenone, was shown to inhibit [Formula: see text]–hexosaminidase secretion from activated mast cells. Our study demonstrated that ethanol extract contained the ingredients, which could inhibit immediate degranulation and de novo synthesis of allergic lipid mediators and cytokines in activated mast cells.
- Published
- 2017
9. Dual compression is not an uncommon type of iliac vein compression syndrome
- Author
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Changjian Liu, Wensheng Lou, Wan-Yin Shi, Jianping Gu, and Xu He
- Subjects
Adult ,Male ,medicine.medical_specialty ,Computed Tomography Angiography ,Venography ,Right Common Iliac Artery ,Constriction, Pathologic ,030204 cardiovascular system & hematology ,Iliac Vein ,Prosthesis Design ,Iliac Artery ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Predictive Value of Tests ,medicine ,Left common iliac vein ,May-Thurner Syndrome ,Humans ,Radiology, Nuclear Medicine and imaging ,External iliac vein ,Cardiac imaging ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Vein compression ,Endovascular Procedures ,Angiography, Digital Subtraction ,Phlebography ,Middle Aged ,medicine.disease ,Compression (physics) ,Stenosis ,Radiographic Image Interpretation, Computer-Assisted ,Female ,Stents ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
Typical iliac vein compression syndrome (IVCS) is characterized by compression of left common iliac vein (LCIV) by the overlying right common iliac artery (RCIA). We described an underestimated type of IVCS with dual compression by right and left common iliac arteries (LCIA) simultaneously. Thirty-one patients with IVCS were retrospectively included. All patients received trans-catheter venography and computed tomography (CT) examinations for diagnosing and evaluating IVCS. Late venography and reconstructed CT were used for evaluating the anatomical relationship among LCIV, RCIA and LCIA. Imaging manifestations as well as demographic data were collected and evaluated by two experienced radiologists. Sole and dual compression were found in 32.3% (n = 10) and 67.7% (n = 21) of 31 patients respectively. No statistical differences existed between them in terms of age, gender, LCIV diameter at the maximum compression point, pressure gradient across stenosis, and the percentage of compression level. On CT and venography, sole compression was commonly presented with a longitudinal compression at the orifice of LCIV while dual compression was usually presented as two types: one had a lengthy stenosis along the upper side of LCIV and the other was manifested by a longitudinal compression near to the orifice of external iliac vein. The presence of dual compression seemed significantly correlated with the tortuous LCIA (p = 0.006). Left common iliac vein can be presented by dual compression. This type of compression has typical manifestations on late venography and CT.
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- 2016
10. Creation of Carotid Fusiform Aneurysm in a Canine Model
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Ming-Hua Li, Wan-Yin Shi, Yue-Qi Zhu, and Lei Yan
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medicine.medical_specialty ,business.industry ,Elastase ,medicine ,Surgery ,Fusiform Aneurysm ,Neurology (clinical) ,Radiology ,Balloon ,business ,Canine model ,Venous graft - Published
- 2012
11. Swine Model of Thrombotic Caval Occlusion Created by Autologous Thrombus Injection with Assistance of Intra-caval Net Knitting
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Jianping Gu, Wan-Yin Shi, Shuang Wu, Lan-Yue Hu, and Changjian Liu
- Subjects
Male ,medicine.medical_specialty ,CD3 Complex ,Swine ,Venography ,Antigens, Differentiation, Myelomonocytic ,Receptors, Cell Surface ,Vena Cava, Inferior ,030204 cardiovascular system & hematology ,Inferior vena cava ,Transplantation, Autologous ,Article ,03 medical and health sciences ,0302 clinical medicine ,Thrombotic occlusion ,Antigens, CD ,Complete occlusion ,Occlusion ,medicine ,Animals ,030212 general & internal medicine ,cardiovascular diseases ,Thrombus ,Multidisciplinary ,medicine.diagnostic_test ,business.industry ,Interleukin-6 ,Macrophages ,Thrombosis ,Phlebography ,medicine.disease ,Venous wall ,Surgery ,Disease Models, Animal ,C-Reactive Protein ,medicine.vein ,cardiovascular system ,Feasibility Studies ,Female ,Thickening ,business ,Biomarkers - Abstract
To evaluate the feasibility of a swine model of thrombotic inferior vena cava (IVC) occlusion (IVCO) created by autologous thrombus injection with assistance of intra-caval net knitting. Sixteen pigs were included and divided into two groups: Group A (n = 10), IVCO model created by knitting a caval net followed by autologous thrombus injection; Group B (n = 6), control model created by knitting a net and normal saline injection. Venography was performed to assess each model and the associated thrombotic occlusion. The vessels were examined histologically to analyse the pathological changes postoperatively. IVCO model was successfully created in 10 animals in Group A (100%). Immediate venography showed extensive clot burden in the IVC. Postoperative venography revealed partial caval occlusion at 7 days and complete occlusion coupled with collateral vessels at 14 days. Histologically, Group A animals had significantly greater venous wall thickening, with CD163-positive and CD3-positive cell infiltration. Recanalization channels were observed at the margins of the thrombus. By contrast, no thrombotic occlusion of the IVC was observed in Group B. The thrombotic IVCO model can be reliably established in swine. The inflammatory reaction may contribute to the caval thrombus propagation following occlusion.
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- 2015
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12. Infundibular dilation: an anatomical variant or a pre-aneurysm? Advantages of assessment with three-dimensional rotational angiography
- Author
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Yong-Dong Li, Min Li, Bei-Lei Zhang, Wu Wang, Bin-Xian Gu, Ming-Hua Li, and Wan-Yin Shi
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Pathology and Forensic Medicine ,Young Adult ,Aneurysm ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Angiography, Digital Subtraction ,Intracranial Aneurysm ,Three dimensional rotational angiography ,Digital subtraction angiography ,Middle Aged ,medicine.disease ,Rotational angiography ,Anatomical relationship ,cardiovascular system ,Dilation (morphology) ,Female ,Surgery ,Radiology ,Anatomy ,business ,Carotid Artery, Internal - Abstract
Whether an infundibular dilation (ID) is an anatomical variant or a pre-aneurysm has not been clearly determined. The aim of the present study was to evaluate the anatomical change of IDs by use of three-dimensional rotational angiography (3DRA) with volume rendering (VR). One-hundred thirty-eight patients with known or suspected aneurysms, treated consecutively, underwent both two-dimensional digital subtraction angiography (2DDSA) and 3DRA with VR. Two readers evaluated the IDs or aneurysms blindly, using 2DDSA and 3DRA, according to the same diagnostic criteria. A 5-point scale of observer confidence was used to determine the presence of IDs or aneurysms. For 3DRA with VR, the relationship between IDs and aneurysms was classified as one of the three types: type I, protrusion or bulge from side wall of IDs; type II, aneurysms involving or enclosing IDs; or type III, aneurysms and IDs coexisting near each other but with some distance between them. The number of IDs found by 2DDSA and 3DRA with VR was 41 and 48, respectively. Five anterior choroidal arteries and two posterior communicating arteries IDs were missed by 2DDSA. According to 3DRA with VR, there were five IDs of type I, nine of type II, and 22 of type III. The 3DRA with VR appears superior to 2DRA for both diagnosing IDs and displaying the anatomical relationship between IDs and aneurysms. The findings also suggest that some IDs might progress to aneurysms or become a part of them, which should be carefully evaluated prior to operation.
- Published
- 2010
13. Two swine models of iliac vein occlusion: Which form most contributes to venous thrombosis?
- Author
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Lan-Yue Hu, Chang-Jian Liu, Wan-Yin Shi, Shuang Wu, and Jianping Gu
- Subjects
Male ,medicine.medical_specialty ,Swine ,Venography ,Blood Pressure ,Constriction, Pathologic ,Iliac Vein ,Occlusion ,medicine ,Animals ,External iliac vein ,Peripheral Vascular Diseases ,Venous Thrombosis ,medicine.diagnostic_test ,business.industry ,Angiography ,Hematology ,Venous blood ,Phlebography ,medicine.disease ,Thrombosis ,Vein occlusion ,Venous thrombosis ,Disease Models, Animal ,Female ,Radiology ,business ,Common iliac vein - Abstract
Objectives In the present study, we establish two swine models of iliac vein occlusion (IVO) with spontaneous thrombosis to understand the mechanisms linking IVO and thrombosis. Methods Two IVO models were established in 12 swine either by ligating the common iliac vein (CIVO) or both the common and external iliac veins (CEIVO). Venography was performed to assess each model and the associated thrombosis. Invasive blood pressure was also measured, and the vessels were examined histologically to analyse the pathological changes after ligation. Results On venography, the CIVO model showed common iliac vein (CIV) occlusion and reflux in the collateral veins whereas the CEIVO model showed occlusion in the CIV and external iliac vein (EIV), stasis in the EIV, and decreased collateral vasculature on venography. Thrombosis was only observed in the CEIVO model, which was with significantly higher venous blood pressure in the EIV and with significantly more thickened venous wall with lymphocytic infiltration histologically. Conclusions Two IVO models can be feasibly and reliably established in swine. The CEIVO model had a higher prevalence of thrombosis than the CIVO model. This CEIVO model produces comparatively less collateral drainage and greater inflammation that can contribute to the thrombosis prone to this type of model.
- Published
- 2015
14. Left ovarian vein dilation or pelvic congestion syndrome secondary to abdominal aortic dissection: incidental findings on CT angiography
- Author
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Guoping Chen, Jian-Ping Gu, Wensheng Lou, and Wan-Yin Shi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Pelvic Pain ,Left ovarian vein ,Pelvis ,Veins ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Aged ,Retrospective Studies ,Aortic dissection ,Aged, 80 and over ,Incidental Findings ,medicine.diagnostic_test ,business.industry ,Ovary ,Reflux ,Angiography ,Syndrome ,Middle Aged ,Pelvic congestion syndrome ,medicine.disease ,Stenosis ,Aortic Dissection ,Dilation (morphology) ,Female ,Radiology ,Complication ,business ,Tomography, X-Ray Computed ,Aortic Aneurysm, Abdominal ,Dilatation, Pathologic - Abstract
Background In the study, we describe eight cases in which pelvic congestion syndrome (PCS) was a direct complication of abdominal aortic dissection (AD). Methods We recorded computed tomographic (CT) details of the AD and PCS. The patterns of pelvic varices and reflux were identified as well. Results All eight had abdominal AD (diameter, 23.44–33.98 mm). The compressed left renal vein revealed stenosis in situ (diameter, 1.17–2.69 mm). CT also revealed dilation of left ovarian vein with left pelvic varices in all cases. Conclusions Some cases of PCS and dilation of the left ovarian vein can be directly correlated with abdominal AD.
- Published
- 2014
15. Combined Direct and Indirect CT Venography (Combined CTV) in Detecting Lower Extremity Deep Vein Thrombosis
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Jianping Gu, Xindao Yin, Wan-Yin Shi, Shao-Juan Wang, and Liwei Wang
- Subjects
Adult ,Male ,Comparative Effectiveness Research ,Duplex ultrasonography ,medicine.medical_specialty ,Deep vein ,030204 cardiovascular system & hematology ,Diagnostic Accuracy Study ,Veins ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,medicine ,Humans ,Venous Thrombosis ,Ultrasonography, Doppler, Duplex ,medicine.diagnostic_test ,business.industry ,Angiography, Digital Subtraction ,Phlebography ,General Medicine ,Digital subtraction angiography ,Middle Aged ,medicine.disease ,Thrombosis ,body regions ,Venous thrombosis ,medicine.anatomical_structure ,Lower Extremity ,Dimensional Measurement Accuracy ,Predictive value of tests ,Angiography ,Female ,Tomography ,Radiology ,Tomography, X-Ray Computed ,business ,Research Article - Abstract
This study aimed to evaluate the diagnostic accuracy of combined direct and indirect CT venography (combined CTV) in the detection of lower extremity deep vein thrombosis (LEDVT). The institutional review board approved the study protocol, and patients or qualifying family members provided informed consent. A total of 96 consecutive patients undergoing combined CTV were prospectively enrolled. A combined examination with digital subtraction angiography (DSA) plus duplex ultrasonography (US) was used as the criterion standard. Three observers were blinded to clinical, DSA, and US results, and they independently analyzed all combined CTV datasets. Interobserver agreement was expressed in terms of the Cohen k value for categorical variables. Accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of combined CTV in the detection of LEDVT were determined by using patient- and location-based evaluations. Of the 96 patients, DSA plus US revealed LEDVT in 125 segmental veins in 63 patients. Patient-based evaluation with combined CTV yielded an accuracy of 96.9% to 97.9%, a sensitivity of 95.2% to 96.8%, a specificity of 100% to 100%, a PPV of 100% to 100%, and an NPV of 91.7% to 94.3% in the detection of LEDVT. Location-based evaluation yielded similar results. Through combined direct and indirect CTV, patients obtained a combined CT angiogram on the diseased limb and an indirect CT angiogram on the opposite side. The image quality of combined CTV was superior to an indirect venogram. Combined CTV shows promising diagnostic accuracy in the detection of LEDVT with 3-dimensional modeling of the lower limb venous system.
- Published
- 2016
16. 3D rotational angiography with volume rendering: the utility in the detection of intracranial aneurysms
- Author
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Ming-Hua Li, Wu Wang, Shi-Wen Chen, Yong-Dong Li, Bin-Xian Gu, Bei-Lei Zhang, Wan-Yin Shi, and Min Li
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Posterior cerebral artery ,Young Adult ,Aneurysm ,Imaging, Three-Dimensional ,medicine.artery ,medicine ,Anterior cerebral artery ,Humans ,cardiovascular diseases ,Aged ,Retrospective Studies ,Aged, 80 and over ,Brain Mapping ,medicine.diagnostic_test ,business.industry ,Angiography, Digital Subtraction ,Intracranial Aneurysm ,Digital subtraction angiography ,Middle Aged ,medicine.disease ,Cerebral Angiography ,body regions ,Neurology ,Rotational angiography ,Middle cerebral artery ,Angiography ,cardiovascular system ,Female ,Neurology (clinical) ,Radiology ,Internal carotid artery ,business - Abstract
Aims: The advent of three-dimensional (3D) rotational angiography (3D DSA) challenged the role of digital subtraction angiography (DSA) as a gold standard in the diagnosis of intracranial aneurysms. In this study, we report our experiences in diagnosing intracranial aneurysms by using 3D DSA with volume rendering (VR) technique, particularly focusing on its role in depicting additional aneurysms missed by 2D DSA. Materials and Methods: One hundred and thirty-eight consecutive patients with known or suspected aneurysms (54 men, 84 women; median age, 55 years; age range, 18-83 years) underwent both conventional DSA and 3D DSA with VR examination simultaneously. The images of 2D DSA or 3D DSA with VR were evaluated by two observers independently for the presence of aneurysms. Then additional aneurysms were decided and depicted. Results: 3D DSA with VR showed 146 aneurysms in 123 (89.1%) of 138 patients and no aneurysms in 15 patients. 2D DSA showed 115 aneurysms in 110 of 137 patients, with one aneurysm in 106 patients each, 2 in 3 patients each and 3 in 1 patient. After reaching a consensus, there were 31 additional aneurysms detected by 3D DSA with VR. 30 aneurysms were
- Published
- 2010
17. Application of dual Willis covered stents in the management of large fusiform carotid aneurysms in a canine model
- Author
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Wan-Yin, Shi, primary, Ming-Hua, Li, additional, Lei, Yan, additional, Yue-Qi, Zhu, additional, and Jian-Ping, Gu, additional
- Published
- 2014
- Full Text
- View/download PDF
18. Combined Direct and Indirect CT Venography (Combined CTV) in Detecting Lower Extremity Deep Vein Thrombosis.
- Author
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Wan-Yin Shi, Li-Wei Wang, Shao-Juan Wang, Xin-Dao Yin, and Jian-Ping Gu
- Published
- 2016
- Full Text
- View/download PDF
19. Azygous Anterior Cerebral Artery and Associated Aneurysms: Detection and Identification Using 3-Dimensional Time-of-Flight Magnetic Resonance Angiography
- Author
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Wan-Yin, Shi, primary, Ming-Hua, Li, additional, Bin-Xian, Gu, additional, Yong-Dong, Li, additional, and Hua-Qiao, Tan, additional
- Published
- 2012
- Full Text
- View/download PDF
20. Left ovarian vein dilation or pelvic congestion syndrome secondary to abdominal aortic dissection: incidental findings on CT angiography.
- Author
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Wan-Yin Shi, Jian-Ping Gu, Wen-Sheng Lou, and Guo-Ping Chen
- Subjects
- *
ABDOMINAL aortic aneurysms , *DISSECTION , *TREATMENT of abdominal aneurysms , *ABDOMINAL surgery , *COMPUTED tomography , *MEDICAL imaging systems - Abstract
Background: In the study, we describe eight cases in which pelvic congestion syndrome (PCS) was a direct complication of abdominal aortic dissection (AD). Methods: Werecorded computed tomographic (CT) details of the AD and PCS. The patterns of pelvic varices and reflux were identified as well. Results: All eight had abdominal AD (diameter, 23.44-33.98 mm). The compressed left renal vein revealed stenosis in situ (diameter, 1.17-2.69 mm). CT also revealed dilation of left ovarian vein with left pelvic varices in all cases. Conclusions: Some cases of PCS and dilation of the left ovarian vein can be directly correlated with abdominal AD. [ABSTRACT FROM AUTHOR]
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- 2015
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21. Correlation Between Angiographic Features and Subtypes of Fusiform Aneurysm of Vertebral and Basilar Artery: Based On a Single-Institution Experience.
- Author
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Wan-Yin Shi, Ming-Hua Li, Jian-Ping Gu, Bin-Xian Gu, and Wu Wang
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- 2015
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22. Application of the Willis covered stent using the telescopic technique for the treatment of fusiform aneurysm in a canine model.
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Lei Yan, Wan-Yin Shi, Dan Wang, Yue-Qi Zhu, Hua-Qiao Tan, Ming-Hua Li, Yan, Lei, Shi, Wan-Yin, Wang, Dan, Zhu, Yue-Qi, Tan, Hua-Qiao, and Li, Ming-Hua
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SURGICAL stents , *ANIMAL models in research , *CORONARY arterial radiography , *HISTOLOGY , *INTRACRANIAL aneurysm surgery , *ANGIOGRAPHY , *ANIMAL experimentation , *DOGS , *TREATMENT effectiveness ,ANEURYSM treatment ,CAROTID artery radiography - Abstract
Background: The covered stent is one of the most promising tools for the treatment of intracranial fusiform aneurysms. We developed an in vivo model of fusiform aneurysms and evaluated the effectiveness of double telescoping Willis covered stents for their treatment.Materials and Methods: An external jugular vein graft was anastomosed with the common carotid artery (CCA) to construct the fusiform aneurysm model. After at least 4 weeks, two Willis covered stents were implanted in a telescopic fashion. Angiography follow-up was performed at 2 weeks and 1 and 3 months to examine the grafts. The animals were sacrificed at 1 or 3 months of the follow-up period, and the stents were examined histologically.Results: A total of eight fusiform aneurysms in four canines were created and 16 covered stents were implanted successfully. No technical or device-related difficulties occurred. The angiographic follow-up results showed that six fusiform aneurysms were completely occluded, and a minimal endoleak occurred in two fusiform aneurysms. Histological examination revealed endothelial progress and all aneurysm sacs were filled with thrombi.Conclusion: Vein graft anastomosis with CCA to construct a model of fusiform aneurysm may reproduce the clinical conditions. This study demonstrated that the implantation of two Willis covered stents in a telescoping fashion is an effective way to treat an experimental model of fusiform aneurysm. [ABSTRACT FROM AUTHOR]- Published
- 2013
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23. Infundibular dilation: an anatomical variant or a pre-aneurysm? Advantages of assessment with three-dimensional rotational angiography.
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Wan-Yin Shi, Yong-Dong Li, Ming-Hua Li, Bin-Xian Gu, Wu Wang, Bei-Lei Zhang, and Min Li
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ANEURYSMS , *ANGIOGRAPHY , *ARTERIAL dilatation , *VASCULAR diseases - Abstract
Purpose: Whether an infundibular dilation (ID) is an anatomical variant or a pre-aneurysm has not been clearly determined. The aim of the present study was to evaluate the anatomical change of IDs by use of three-dimensional rotational angiography (3DRA) with volume rendering (VR). Methods: One-hundred thirty-eight patients with known or suspected aneurysms, treated consecutively, underwent both two-dimensional digital subtraction angiography (2DDSA) and 3DRA with VR. Two readers evaluated the IDs or aneurysms blindly, using 2DDSA and 3DRA, according to the same diagnostic criteria. A 5-point scale of observer confidence was used to determine the presence of IDs or aneurysms. For 3DRA with VR, the relationship between IDs and aneurysms was classified as one of the three types: type I, protrusion or bulge from side wall of IDs; type II, aneurysms involving or enclosing IDs; or type III, aneurysms and IDs coexisting near each other but with some distance between them. Results: The number of IDs found by 2DDSA and 3DRA with VR was 41 and 48, respectively. Five anterior choroidal arteries and two posterior communicating arteries IDs were missed by 2DDSA. According to 3DRA with VR, there were five IDs of type I, nine of type II, and 22 of type III. Conclusions: The 3DRA with VR appears superior to 2DRA for both diagnosing IDs and displaying the anatomical relationship between IDs and aneurysms. The findings also suggest that some IDs might progress to aneurysms or become a part of them, which should be carefully evaluated prior to operation. [ABSTRACT FROM AUTHOR]
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- 2011
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24. 3D rotational angiography with volume rendering: The utility in the detection of intracranial aneurysms.
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Wan-Yin Shi, Yong-Dong Li, Ming-Hua Li, Bin-Xian Gu, Shi-Wen Chen, Wu Wang, Bei-Lei Zhang, and Min Li
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DIGITAL subtraction angiography , *INTRACRANIAL aneurysm diagnosis , *BRAIN blood-vessels , *DIGITAL angiography , *DIGITAL diagnostic imaging , *DIAGNOSIS of brain diseases - Abstract
Aims: The advent of three-dimensional (3D) rotational angiography (3D DSA) challenged the role of digital subtraction angiography (DSA) as a "gold standard" in the diagnosis of intracranial aneurysms. In this study, we report our experiences in diagnosing intracranial aneurysms by using 3D DSA with volume rendering (VR) technique, particularly focusing on its role in depicting additional aneurysms missed by 2D DSA. Materials and Methods: One hundred and thirty-eight consecutive patients with known or suspected aneurysms (54 men, 84 women; median age, 55 years; age range, 18-83 years) underwent both conventional DSA and 3D DSA with VR examination simultaneously. The images of 2D DSA or 3D DSA with VR were evaluated by two observers independently for the presence of aneurysms. Then additional aneurysms were decided and depicted. Results: 3D DSA with VR showed 146 aneurysms in 123 (89.1%) of 138 patients and no aneurysms in 15 patients. 2D DSA showed 115 aneurysms in 110 of 137 patients, with one aneurysm in 106 patients each, 2 in 3 patients each and 3 in 1 patient. After reaching a consensus, there were 31 additional aneurysms detected by 3D DSA with VR. 30 aneurysms were <3 mm in maximum diameter with 3 aneurysms ruptured. These additional aneurysms were located in internal carotid artery (ICA, n = 28, 90.32%), anterior cerebral artery (ACA, n = 3, 9.68%). No additional aneurysms were found in either middle cerebral artery (MCA) or vertebrobasilar and posterior cerebral artery (PCA) systems. Conclusions: 3D DSA, especially VR images, not only clearly reveals aneurysms and aneurysmal morphology, but also detects additional aneurysms missed by 2D DSA, especially small aneurysms less than 3 mm. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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