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203 results on '"Wang, Chuanmin"'

1. Piezoelectric thin films and their applications in MEMS: A review.

Author

Liu, Jinpeng, Tan, Hua, Zhou, Xinyi, Ma, Weigang, Wang, Chuanmin, Tran, Nguyen-Minh-An, Lu, Wenlong, Chen, Feng, Wang, Junya, and Zhang, Haibo

Subjects
PIEZOELECTRIC thin films, PIEZOELECTRICITY, PIEZOELECTRIC materials, THIN films, MICROELECTROMECHANICAL systems
Abstract

With the increasing demand for devices in miniaturization, accuracy, and low power consumption, developing microdevices in the form of piezoelectric thin films is significant for microelectromechanical systems (MEMS) applications. Piezoelectric thin films offer advantages of miniaturization and low power consumption, holding immense potential in MEMS, especially with advancements in micro-nanomanufacturing technologies. In this review, we highlighted the compelling piezoelectric properties and summarized the latest research progress of thin films, with an emphasis on recent advances in piezoelectric MEMS. We mainly introduced the recent developments on different types of piezoelectric MEMS (piezo-MEMS), along with the descriptions of piezoelectric effects, film preparation, film properties, and device indicators. We have emphasized the comparison of MEMS with different piezoelectric materials and methods for improving devices. The recent achievements of piezoelectric thin films in MEMS applications and the future development of MEMS applications are also reviewed. [ABSTRACT FROM AUTHOR]

Published
2025
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14. 212.7: Factors Determining the Ex-vivo Survival of Human Livers More Than 1 Week Under Normothermic Conditions: Understanding the Requirements for Long-term Survival of Organs

Author

Lau, Ngee-Soon, Ly, Mark, Dennis, Claude, Huang, Joanna Lou, Huang, Joanna, Jacques, Andrew, Cabanes-Creus, Marti, Toomath, Shamus, Mestrovic, Nicole, Yousif, Paul, Chanda, Sumon, Wang, Chuanmin, Lisowski, Leszek, Liu, Ken, Kench, James, McCaughan, Geoffrey, Crawford, Michael, and Pulitano, Carlo

Published
2022
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20. Long-term ex-vivo normothermic perfusion of human split livers: a unique model to study new therapeutics and increase the number of available organs

Author

Lau, Ngee-Soon, primary, Ly, Mark, additional, Dennis, Claude, additional, Jacques, Andrew, additional, Cabanes-Creus, Marti, additional, Toomath, Shamus, additional, Huang, Joanna, additional, Mestrovic, Nicole, additional, Yousif, Paul, additional, Chanda, Sumon, additional, Wang, Chuanmin, additional, Lisowski, Leszek, additional, Liu, Ken, additional, Kench, James, additional, McCaughan, Geoffrey, additional, Crawford, Michael, additional, and Pulitano, Carlo, additional

Published
2023
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23. Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs

Author

Keane, Fiona M., Yao, Tsun-Wen, Seelk, Stefanie, Gall, Margaret G., Chowdhury, Sumaiya, Poplawski, Sarah E., Lai, Jack H., Li, Youhua, Wu, Wengen, Farrell, Penny, Vieira de Ribeiro, Ana Julia, Osborne, Brenna, Yu, Denise M.T., Seth, Devanshi, Rahman, Khairunnessa, Haber, Paul, Topaloglu, A. Kemal, Wang, Chuanmin, Thomson, Sally, Hennessy, Annemarie, Prins, John, Twigg, Stephen M., McLennan, Susan V., McCaughan, Geoffrey W., Bachovchin, William W., and Gorrell, Mark D.

Published
2014
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24. Research Status and Development Trend of Piezoelectric Accelerometer.

Author

Wu, Tianqiong, You, Di, Gao, Huayun, Lian, Pinghua, Ma, Weigang, Zhou, Xinyi, Wang, Chuanmin, Luo, Jianghai, Zhang, Haibo, and Tan, Hua

Subjects
PIEZOELECTRIC materials, RESEARCH & development, PIEZOELECTRIC detectors
Abstract

Piezoelectric accelerometers have been widely used because of their large range, simple structure, stable performance, and other advantages. With the improvement of science and technology, the application field is expanding, but there are still some problems in high-temperature environments and low-frequency vibration conditions. Under high-temperature environments, the piezoelectric material will undergo depolarization or resistance change, resulting in sensor failure. Aerospace instruments, water conservancy platforms, and other fields require high-precision instruments with vibration amplitudes of the order of a few microns in the range of 0.01–1 Hz, which require low-frequency and ultra-low-frequency sensors for the measurements. Therefore, how to increase the operating temperature and reduce the noise of piezoelectric accelerometers has become a problem that needs to be solved. This paper reviews the structure, principle, application range, and material selection of piezoelectric components of different types of piezoelectric accelerometers and summarizes the current problems and future research priorities. [ABSTRACT FROM AUTHOR]

Published
2023
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29. Theoretical and Experimental Flow Characteristics of a Large-Scale Annular Channel in Terms of Deformation Gradient, Eccentricity, and Water Compressibility.

Author

Zhao, Shendan, Liu, Yinshui, Wu, Defa, Wang, Chuanmin, and Wang, Zhenyao

Subjects
COMPRESSIBILITY, DEFORMATIONS (Mechanics), LAMINAR flow, TURBULENT flow, ANNULAR flow, SALINE water conversion
Abstract

Hydraulic water plunger pumps have come to be widely used in coal mining, seawater desalination, and oil exploitation due to their high output pressure and large flow characteristics. In a high-pressure large-flow plunger pump, the leakage of the annular channel of the plunger pair is an essential factor affecting volume efficiency. The axial pressure gradient exists in the fluid inside the annular channel, resulting in the plunger and plunger sleeve forming similar funnel-like shapes. Moreover, the characteristics of large diameter, high working pressure, and low fluid viscosity of the plunger pump will lead to the complicated flow of the annular channel. The influence of eccentricity and structural deformation on leakage is difficult to evaluate. Therefore, considering the deformation gradient and eccentricity of the plunger pair and the compressibility of the water, the deformation equations and leakage equations of the annular channel under the laminar and turbulent flow state are derived in this study. The eccentricity and leakage of the annular channel under different pressure conditions are measured using a built sealing test bench. It is proved that the discrepancy between the calculated model and the experimental results is less than 6% under different pressures, which effectively predicts the sealing performance of plunger pumps. The results show that under the laminar flow condition, the effects of eccentricity, structural deformation, and medium compressibility on leakage are 148%, 4.92%, and 0.92%, respectively. In turbulent conditions, they were 31%, 2.84%, and 1.19%, respectively. Besides, the reasonable material pairing of the plunger friction pair can reduce the variation of leakage due to structural deformation. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4+CD25+ Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor

Author

Hall, Bruce M., primary, Hall, Rachael M., additional, Tran, Giang T., additional, Robinson, Catherine M., additional, Wilcox, Paul L., additional, Rakesh, Prateek K., additional, Wang, Chuanmin, additional, Sharland, Alexandra F., additional, Verma, Nirupama D., additional, and Hodgkinson, Suzanne J., additional

Published
2021
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33. Comparison of Single-Event Transients in an Epitaxial Silicon Diode Resulting From Heavy-Ion-, Focused X-Ray-, and Pulsed Laser-Induced Charge Generation

Author

Ryder, Kaitlyn L., primary, Ryder, Landen D., additional, Sternberg, Andrew L., additional, Kozub, John A., additional, Zhang, En Xia, additional, LaLumondiere, Stephen D., additional, Monahan, Daniele M., additional, Bonsall, Jeremy P., additional, Khachatrian, Ani, additional, Buchner, Stephen P., additional, McMorrow, Dale, additional, Hales, Joel M., additional, Zhao, Yuanfu, additional, Wang, Liang, additional, Wang, Chuanmin, additional, Weller, Robert A., additional, Schrimpf, Ronald D., additional, Weiss, Sharon M., additional, and Reed, Robert A., additional

Published
2021
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35. Simulation of Pulsed Laser-Induced Testing in Microelectronic Devices

Author

Ryder, Landen D., primary, Ryder, Kaitlyn L., additional, Sternberg, Andrew L., additional, Kozub, John A., additional, Khachatrian, Ani, additional, Buchner, Steven P., additional, McMorrow, Dale, additional, Hales, Joel M., additional, Zhao, Yuanfu, additional, Wang, Liang, additional, Wang, Chuanmin, additional, Weller, Robert A., additional, Schrimpf, Ronald D., additional, Weiss, Sharon M., additional, and Reed, Robert A., additional

Published
2021
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36. Scalable Synthesis, In Vitro cccDNA Reduction, and In Vivo Antihepatitis B Virus Activity of a Phosphonomethoxydeoxythreosyl Adenine Prodrug

Author

Luo, Min, primary, Wu, Shuo, additional, Kalkeri, Raj, additional, Ptak, Roger G., additional, Zhou, Tianlun, additional, Van Mellaert, Lieve, additional, Wang, Chuanmin, additional, Dumbre, Shrinivas G., additional, Block, Timothy, additional, Groaz, Elisabetta, additional, De Jonghe, Steven, additional, Li, Yuhuan, additional, and Herdewijn, Piet, additional

Published
2020
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37. Gut Microbial Metabolites Induce Donor-Specific Tolerance of Kidney Allografts through Induction of T Regulatory Cells by Short-Chain Fatty Acids

Author

Wu, Huiling, primary, Singer, Julian, additional, Kwan, Tony K., additional, Loh, Yik Wen, additional, Wang, Chuanmin, additional, Tan, Jian, additional, Li, Yan J., additional, Lai, Sum Wing Christina, additional, Macia, Laurence, additional, Alexander, Stephen I., additional, and Chadban, Steven J., additional

Published
2020
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38. Value of serum PCT in early diagnosis of bacterial infection in patients with liver failure

Author

WANG Chuanmin, MENG Zhongji, and CHEN Yue

Subjects
lcsh:Diseases of the digestive system. Gastroenterology, lcsh:RC799-869
Abstract

ObjectiveTo investigate the value of serum procalcitonin (PCT) in early diagnosis of bacterial infection in patients with liver failure. MethodsA total of 463 patients with hepatitis B were selected from January to December, 2014, in the Department of Infectious Diseases, Taihe Hospital. According to the degree of liver injury, the patients were divided into four groups: mild liver injury group (n=120), moderate liver injury group (n=222), sever liver injury group (n=53), and liver failure group (n=68). Serum PCT was measured for all patients, and the white blood cell count (WBC) and high-sensitivity C-reactive protein (hsCRP) were measured for patients with liver failure. The clinical manifestations were observed and recorded. The t test was used for comparison of normally distributed continuous data, while the Kruskal-Wallis H test was used for non-normally distributed continuous data; the Mann-Whitney U test was used for pairwise comparison of continuous data. The chi-square test was used for comparison of categorical data. The receiver operating characteristic (ROC) curve was used for the analysis of predictive value. ResultsThe liver failure group had a significantly higher PCT level than the severe liver injury group, moderate liver injury group, and mild liver injury group (0.81［0.34-2.15］ vs 0.53［0.21-1.59］, 0.35［010-1.18］, and 0.17［0.10-0.60］, χ2=25.091, P＜0.05). The liver failure patients with PCT levels of ＜0.25 ng/ml (n=10), 0.25-0.5 ng/ml (n=10), and ＞0.5 ng/ml (n=48) had infection rates of 20%, 30%, and 66.7%, respectively, with a significant difference between the patients with a PCT level of ＞0.5 ng/ml and those with PCT levels of ＜0.25 ng/ml and 0.25-0.5 ng/ml (χ2=5631,4650,P=0018,0031). Among the liver failure patients, the infection cases had significantly higher PCT, WBC, and hsCRP than the non-infection cases (PCT: 3.72±1.33 ng/ml vs 0.34±0.12 ng/ml, t=-2.547, P=0.015; hsCRP: 16.70±7.03 mg/L vs 11.00±6.52 mg/L, t=-3.458, P=0.001); the hsCRP level in both infection and non-infection cases was higher than the normal value, and the WBC in both infection and non-infection cases was lower than the normal value. In the 37 liver failure patients with infection, 13 (35.14%) had no symptoms and signs associated with infection, but had significantly increased serum PCT. As for the predictive value of PCT for bacterial infection, the area under the ROC curve was 0.691, with a sensitivity of 0.737 and a specificity of 0.700. ConclusionThe patients with liver failure are susceptible to bacterial infection. Serum PCT measurement has great significance for early diagnosis of bacterial infection in patients with liver failure.

Published
2017

46. Interleukin-5 (IL-5) Therapy Prevents Allograft Rejection by Promoting CD4+CD25+ Ts2 Regulatory Cells That Are Antigen-Specific and Express IL-5 Receptor.

Author

Hall, Bruce M., Hall, Rachael M., Tran, Giang T., Robinson, Catherine M., Wilcox, Paul L., Rakesh, Prateek K., Wang, Chuanmin, Sharland, Alexandra F., Verma, Nirupama D., and Hodgkinson, Suzanne J.

Subjects
GRAFT rejection, REGULATORY T cells, INTERLEUKIN-5, GRAFT survival, T cells, REJECTION (Psychology)
Abstract

CD4+CD25+Foxp3+T cell population is heterogenous and contains three major sub-groups. First, thymus derived T regulatory cells (tTreg) that are naïve/resting. Second, activated/memory Treg that are produced by activation of tTreg by antigen and cytokines. Third, effector lineage CD4+CD25+T cells generated from CD4+CD25- T cells' activation by antigen to transiently express CD25 and Foxp3. We have shown that freshly isolated CD4+CD25+T cells are activated by specific alloantigen and IL-4, not IL-2, to Ts2 cells that express the IL-5 receptor alpha. Ts2 cells are more potent than naïve/resting tTreg in suppressing specific alloimmunity. Here, we showed rIL-5 promoted further activation of Ts2 cells to Th2-like Treg, that expressed foxp3, irf4, gata3 and il5. In vivo , we studied the effects of rIL-5 treatment on Lewis heart allograft survival in F344 rats. Host CD4+CD25+T cells were assessed by FACS, in mixed lymphocyte culture and by RT-PCR to examine mRNA of Ts2 or Th2-like Treg markers. rIL-5 treatment given 7 days after transplantation reduced the severity of rejection and all grafts survived ≥60d whereas sham treated rats fully rejected by day 31 (p<0.01). Treatment with anti-CD25 or anti-IL-4 monoclonal antibody abolished the benefits of treatment with rIL-5 and accelerated rejection. After 10d treatment with rIL-5, hosts' CD4+CD25+ cells expressed more Il5ra and responded to specific donor Lewis but not self. Enriched CD4+CD25+ cells from rIL-5 treated rats with allografts surviving >60 days proliferated to specific donor only when rIL-5 was present and did not proliferate to self or third party. These cells had more mRNA for molecules expressed by Th2-like Treg includin g Irf4, gata3 and Il5. These findings were consistent with IL-5 treatment preventing rejection by activation of Ts2 cells and Th2-like Treg. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Early Prognostic Utility of Gp210 Antibody-Positive Rate in Primary Biliary Cholangitis: A Meta-Analysis

Author

Huang, Chunyang, Han, Weijia, Wang, Chuanmin, Liu, Yanmin, Chen, Yue, and Duan, Zhongping

Subjects
Article Subject, digestive system, digestive system diseases
Abstract

Background. The prevalence of primary biliary cholangitis (PBC), which is an autoimmune liver disease, has increased over time. PBC often leads to severe consequences, such as liver failure and death. Stratification tools using biochemical liver tests are needed to assess and predict the progression of this disease at the time of PBC diagnosis. Methods. We searched PubMed, Cochrane Library, Web of Science, and Embase for studies focused on the relationship between positive rates of Gp210 antibodies and poor prognosis of PBC. The primary end point was the number of PBC patients with poor outcome in the Gp210 antibody (+) and Gp210 antibody (−) groups. The secondary end point was the basic serum level of alanine aminotransferase (ALT), alkaline phosphatase (ALP), total bilirubin (TBIL), and IgM in the two groups. The age and number of female patients were also measured. Results. A total of 5 studies, comprising 737 patients, were included in this analysis. A positive rate of Gp210 antibodies was positively correlated with poor outcomes and with many types of progression in PBC, especially liver failure. Mortality was also higher in the Gp210 antibody (+) group. Furthermore, the serum levels of ALP and IgM were associated with the positive rate of Gp210 antibodies, while the serum levels of ALT and TBIL were not. The age and number of female patients were also not associated with the positive rate of Gp210 antibodies. Conclusion. PBC-specific Gp120 antibodies are optimal predictors of PBC prognosis at the time of diagnosis. Some other liver function indicators, such as ALP and IgM, can be used as predictors to complement Gp210 antibodies to establish a stratification tool to predict the prognosis of PBC at the time of diagnosis.

Published
2019
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48. Comparison of Sensitive Volumes Associated With Ion- and Laser-Induced Charge Collection in an Epitaxial Silicon Diode

Author

Ryder, Kaitlyn L., primary, Zhao, Yuanfu, additional, Wang, Liang, additional, Wang, Chuanmin, additional, Weller, Robert A., additional, Schrimpf, Ronald D., additional, Weiss, Sharon M., additional, Reed, Robert A., additional, Ryder, Landen D., additional, Sternberg, Andrew L., additional, Kozub, John A., additional, Zhang, En Xia, additional, Khachatrian, Ani, additional, Buchner, Steven P., additional, Mcmorrow, Dale P., additional, and Hales, Joel M., additional

Published
2020
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